2,381 results match your criteria Dumping Syndrome


[Postprandial Abdominal Fullness after Pylorus-Preserving Gastrectomy for Early Gastric Cancer].

Gan To Kagaku Ryoho 2018 Dec;45(13):2138-2140

Dept. of Surgery, The Nippon Dental University, School of Life Dentistry.

To clarify the basis for postprandial abdominal fullness(PAF)in patients after pylorus-preserving gastrectomy(PPG), the authors investigated the relationship of PAF with postgastrectomy disorder(PGD)and gastric emptying function(GEF)in PPG patients. A total of 22 patients(14 men and 8 women, average age 64.8 years)were divided into 2 groups[Group A, PAF-positive(n=12); Group B, PAF-negative(n=10)]at 1 year after PPG for early gastric cancer. Read More

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December 2018
9 Reads

Fertility, Pregnancy and Lactation After Bariatric Surgery - a Consensus Statement from the OEGGG.

Geburtshilfe Frauenheilkd 2018 Dec 14;78(12):1207-1211. Epub 2018 Dec 14.

Universitätsklinik für Frauenheilkunde, Klinische Abteilung für Geburtshilfe und feto-maternale Medizin, Medizinische Universität, Wien, Austria.

Bariatric surgery is recommended when other weight loss interventions, such as lifestyle modification or medications, have failed. A considerable number of women undergoing bariatric surgery are of childbearing age; hence, it is necessary to be aware of the effects of bariatric surgery on pregnancy for managing these patients. Although bariatric surgery is associated with positive effects on cardiovascular and metabolic parameters, side effects such as anaemia, the risk of developing internal hernia, altered glucose metabolism and the risk of small for gestational age offspring have to be considered. Read More

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http://dx.doi.org/10.1055/a-0706-7578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294640PMC
December 2018
2 Reads

Prevalence of Dumping Syndrome After Laparoscopic Sleeve Gastrectomy and Comparison with Laparoscopic Roux-en-Y Gastric Bypass.

Obes Surg 2019 Jan 11. Epub 2019 Jan 11.

Mather Hospital Northwell Health, 625 Belle Terre Road, Port Jefferson, NY, 11777, USA.

Background: Dumping syndrome is a well-known side effect of laparoscopic gastric bypass (LRYGB), and it is commonly believed that dumping syndrome is less likely to occur after laparoscopic sleeve gastrectomy (LSG), due to the preservation of the pyloric sphincter. However, it is not uncommon for patients undergoing LSG at our center to report symptoms suggestive of dumping syndrome.

Objective: To assess the prevalence of symptoms of dumping syndrome after LSG compared with LRYGB. Read More

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http://dx.doi.org/10.1007/s11695-018-03699-yDOI Listing
January 2019
1 Read

Short-Term Outcomes of Sleeve Gastrectomy plus Jejunojejunal Bypass: a Retrospective Comparative Study with Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in Chinese Patients with BMI ≥ 35 kg/m.

Obes Surg 2019 Jan 11. Epub 2019 Jan 11.

Department of General surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.

Background: Bariatric surgery represents the most effective treatment for obesity and its related comorbidities. The present study aims to evaluate the efficacy and safety of sleeve gastrectomy plus jejunojejunal bypass (SG + JJB).

Methods: This retrospective study included 244 obese patients with BMI ≥ 35 kg/m undergoing SG + JJB (n = 83), SG (n = 82), and Roux-en-Y gastric bypass (RYGB) (n = 79). Read More

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http://link.springer.com/10.1007/s11695-018-03688-1
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http://dx.doi.org/10.1007/s11695-018-03688-1DOI Listing
January 2019
4 Reads

Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome.

BMC Pregnancy Childbirth 2018 Dec 27;18(1):507. Epub 2018 Dec 27.

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Bariatric surgery (BS) is regarded to be the most effective treatment of obesity with long lasting beneficial effects including weight loss and improvement of metabolic disorders. A considerable number of women undergoing BS are at childbearing age.Although the surgery mediated weight loss has a positive effect on pregnancy outcome, the procedures might be associated with adverse outcomes as well, for example micronutrient deficiencies, iron or B12 deficiency anemia, dumping syndrome, surgical complications such as internal hernias, and small for gestational age (SGA) offspring, possibly due to maternal undernutrition. Read More

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http://dx.doi.org/10.1186/s12884-018-2124-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307154PMC
December 2018
2 Reads

Pouch Versus No Pouch Following Total gastrectomy: Meta-analysis of Randomized and Non-randomized Studies.

Ann Surg 2018 Dec 6. Epub 2018 Dec 6.

Department of Surgery, University Surgical Cluster, National University Health System, Singapore.

Objective: The aim of the study was to assess the impact of pouch reconstruction on perioperative outcomes, postprandial symptoms, nutritional and anthropometric parameters, and overall quality of life after total gastrectomy for gastric malignancy.

Summary Background Data: The short-term perioperative risks and longer term functional value of creating a small-bowel reservoir after total gastrectomy are contended.

Methods: A search for randomized and non-randomized studies comparing reconstruction with or without a pouch was conducted. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003082DOI Listing
December 2018
3 Reads
8.327 Impact Factor

Diagnosis and treatment of chronic abdominal pain 5 years after Roux-en-Y gastric bypass.

Surg Obes Relat Dis 2018 Oct 14;14(10):1544-1551. Epub 2018 Jun 14.

Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway; Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway.

Background: Knowledge of optimal diagnostic workup, etiology, and response to treatment of chronic abdominal pain after Roux-en-Y gastric bypass (RYGB) is limited.

Objective: To define the etiology of chronic abdominal pain presenting at the 5-year follow-up after RYGB and to evaluate response to treatment.

Setting: Oslo University Hospital (tertiary referral center for obesity surgery). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15507289183030
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http://dx.doi.org/10.1016/j.soard.2018.06.004DOI Listing
October 2018
10 Reads

Dysregulated glucose homeostasis in congenital central hypoventilation syndrome.

J Pediatr Endocrinol Metab 2018 Dec;31(12):1325-1333

Department of Endocrinology and Diabetes, Lady Cilento Children's Hospital, South Brisbane, Queensland, Australia.

Background Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic control. A hypoglycaemic seizure in a 4-year-old girl with CCHS led to a more detailed examination of glycaemic control in a cohort of children with CCHS. Methods We conducted an observational cohort study of glucose homeostasis in seven children (3 months to 12 years) with genetically confirmed CCHS using a combination of continuous glucose monitoring (CGM), fasting studies and oral glucose tolerance test (OGTT). Read More

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http://www.degruyter.com/view/j/jpem.ahead-of-print/jpem-201
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http://dx.doi.org/10.1515/jpem-2018-0086DOI Listing
December 2018
8 Reads

Prevalence and pathophysiology of early dumping in patients after primary Roux-en-Y gastric bypass during a mixed-meal tolerance test.

Surg Obes Relat Dis 2018 Oct 12. Epub 2018 Oct 12.

Department of Bariatric and Metabolic Surgery, Heelkunde Friesland Groep, Medical Center Leeuwarden, Leewarden, the Netherlands; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background: Early dumping is a poorly defined and incompletely understood complication after Roux-en-Y gastric (RYGB).

Objective: We performed a mixed-meal tolerance test in patients after RYGB to address the prevalence of early dumping and to gain further insight into its pathophysiology.

Setting: The study was conducted in a regional hospital in the northern part of the Netherlands. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15507289183039
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http://dx.doi.org/10.1016/j.soard.2018.10.004DOI Listing
October 2018
8 Reads

Applications of peptide hormone ligands for the treatment of dumping and short bowel syndrome.

Curr Opin Pharmacol 2018 Dec 28;43:118-123. Epub 2018 Sep 28.

Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Herestraat 49, 3000 Leuven, Belgium; Leuven Intestinal Failure and Transplantation Center (LIFT), University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

Dumping syndrome is a common and debilitating complication of upper gastrointestinal surgery. Accelerated gastric emptying and dysregulated secretion of gastrointestinal (GI) hormones are involved in its pathophysiology. Pasireotide, a novel somatostatin analogue, improved dumping in a phase-2 study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14714892183007
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http://dx.doi.org/10.1016/j.coph.2018.09.005DOI Listing
December 2018
5 Reads

Endoscopic Gastrojejunal Revisions Following Gastric Bypass: Lessons Learned in More Than 100 Consecutive Patients.

J Gastrointest Surg 2019 Jan 13;23(1):58-66. Epub 2018 Sep 13.

Department of Visceral Surgery, Hirslanden Clinic Beau-Site, Schaenzlihalde 1, CH-3013, Berne, Switzerland.

Background: Weight regain and dumping after Roux-en-Y gastric bypass (RYGB) are long-term challenges thought to be due to dilation of the gastrojejunal anastomosis. The aim of this study was to analyze the feasibility, safety, and outcomes of endoscopic gastrojejunal revisions (EGRs) after its introduction in a tertiary bariatric surgery center.

Methods: From January 2016 to March 2018, we reviewed the electronic records of all patients undergoing EGR with the OverStitch suturing device. Read More

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http://link.springer.com/10.1007/s11605-018-3961-0
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http://dx.doi.org/10.1007/s11605-018-3961-0DOI Listing
January 2019
7 Reads

Transient severe distributive shock due to early dumping syndrome: a case report.

J Med Case Rep 2018 Sep 13;12(1):259. Epub 2018 Sep 13.

Department of Emergency and Critical Care Medicine, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Background: Early dumping syndrome characterized by palpitation, dizziness, cold sweat, feebleness, and abdominal symptoms, occurs within 30 minutes after meals in patients who have undergone gastrectomy. This case report describes the case of a patient who presented with severe distributive shock due to early dumping syndrome; he recovered within a few hours after massive fluid infusion and vasopressor administration.

Case Presentation: Our patient was a 68-year-old Japanese man who underwent total gastrectomy for gastric cancer and was diagnosed as having late dumping syndrome. Read More

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http://dx.doi.org/10.1186/s13256-018-1800-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136219PMC
September 2018
2 Reads

Mentorship Programs in Bariatric Surgery Reduce Perioperative Complication Rate at Equal Short-Term Outcome-Results from the OPTIMIZE Trial.

Obes Surg 2019 Jan;29(1):127-136

Department of General-, Visceral- and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Objectives: The aim of this study was to determine the efficacy of coaching on outcome in low volume centers of excellence and to evaluate the influence of mentorship programs on the center development.

Background: The number of bariatric procedures has increased steadily in the last years. Providing nationwide bariatric care on a high professional level needs structures to train and guide upcoming centers and ensure high quality in patient care. Read More

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http://dx.doi.org/10.1007/s11695-018-3495-2DOI Listing
January 2019
4 Reads

Evaluation of resection of the gastroesophageal junction and jejunal interposition (Merendino procedure) as a rescue procedure in patients with a failed redo antireflux procedure. A single-center experience.

BMC Surg 2018 Aug 30;18(1):70. Epub 2018 Aug 30.

Centre for Digestive Diseases, Karolinska University Hospital and Division of Surgery, Department of Clinical Intervention and Technology (CLINTEC), Karolinska Institutet, Stockhom, Sweden.

Background: Primary antireflux surgery has high success rates but 5 to 20% of patients undergoing antireflux operations can experience recurrent reflux and dysphagia, requiring reoperation. Different surgical approaches after failed fundoplication have been described in the literature. The aim of this study was to evaluate resection of the gastroesophageal junction with jejunal interposition (Merendino procedure) as a rescue procedure after failed fundoplication. Read More

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https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-01
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http://dx.doi.org/10.1186/s12893-018-0401-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117955PMC
August 2018
7 Reads

Jejunal pouch reconstruction after total gastrectomy is associated with better short-term absorption capacity and quality of life in early-stage gastric cancer patients.

BMC Surg 2018 Aug 20;18(1):63. Epub 2018 Aug 20.

Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Wuhan, 430014, People's Republic of China.

Background: No consensus exists regarding the best reconstruction style after total gastrectomy (TG). Roux-en-Y oesophagojejunostomy is a simple option for gastrointestinal tract reconstruction. Recently, jejunal pouch reconstruction has been suggested as an appropriate approach. Read More

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http://dx.doi.org/10.1186/s12893-018-0397-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102876PMC
August 2018
2 Reads

Post-Prandial Hyperinsulinaemic Hypoglycaemia after Oesophageal Surgery in Children.

Horm Res Paediatr 2018 Aug 9:1-5. Epub 2018 Aug 9.

Endocrinology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.

Introduction: Post-prandial hyperinsulinaemic hypoglycaemia (PPHH) is a recognized complication of various gastric surgeries in children, but rarely reported after oesophageal atresia repair. We report 2 children diagnosed with PPHH after oesophageal surgery and the challenges of their management. Case 1: A 2-year-old boy diagnosed with oesophageal atresia at birth was surgically repaired requiring 6 oesophageal dilatations in the first year of life. Read More

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http://dx.doi.org/10.1159/000491647DOI Listing
August 2018
4 Reads

Long-term self-reported symptom prevalence of early and late dumping in a patient population after sleeve gastrectomy, primary, and revisional gastric bypass surgery.

Surg Obes Relat Dis 2018 Aug 24;14(8):1173-1181. Epub 2018 Apr 24.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background: Early and late dumping are side effects of bariatric surgery. Almost no data are available on the prevalence of dumping after different surgical procedures.

Objectives: Comparison of the relative risks of dumping in a large population of patients having undergone primary Roux-en-Y gastric bypass (pRYGB), sleeve gastrectomy (SG), or revisional RYGB (rRYGB; after removal of band). Read More

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http://dx.doi.org/10.1016/j.soard.2018.04.011DOI Listing
August 2018
2 Reads

Does pregnancy interval after laparoscopic sleeve gastrectomy affect maternal and perinatal outcomes?

J Matern Fetal Neonatal Med 2018 May 17:1-7. Epub 2018 May 17.

c Department of Obstetrics and Gynecology , SB Istanbul Medeniyet University Goztepe Education and Research Hospital , Istanbul , Turkey.

Background: Obesity is a global health epidemic and is associated with many maternal and neonatal complications. Laparoscopic sleeve gastrectomy (LSG) is among the surgical treatments for obesity. The appropriate timing of pregnancy following LSG remains controversial and few studies have evaluated this public health issue. Read More

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http://dx.doi.org/10.1080/14767058.2018.1471678DOI Listing
May 2018
3 Reads

Safety and efficacy of pasireotide in dumping syndrome-results from a phase 2, multicentre study.

Aliment Pharmacol Ther 2018 Jun 25;47(12):1661-1672. Epub 2018 Apr 25.

Groningen, The Netherlands.

Background: Dumping syndrome is a prevalent complication of oesophageal and gastric surgery characterised by early (postprandial tachycardia) and late (hypoglycaemia) postprandial symptoms.

Aim: To evaluate efficacy and safety of the somatostatin analogue, pasireotide in patients with dumping syndrome after bariatric or upper gastrointestinal cancer surgery.

Methods: A single-arm, open-label, multicentre, intrapatient dose-escalation, phase 2 study with 4 phases: screening, 3-month SC (subcutaneous), 3-month IM (intramuscular) and 6-month optional extension IM phase. Read More

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http://doi.wiley.com/10.1111/apt.14664
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http://dx.doi.org/10.1111/apt.14664DOI Listing
June 2018
23 Reads

An Extremely Rare Bile Leakage: Aberrant Bile Duct in Left Triangular Ligament (Appendix Fibrosa Hepatis).

Case Rep Surg 2018 31;2018:1259561. Epub 2018 Jan 31.

Department of General Surgery, Suleyman Demirel University Medical School, Isparta, Turkey.

Background: The anatomical variability of bile ducts can leave surgeons in very difficult conditions.Ultrasonography, computed tomography, magnetic resonance imaging (MRCP) and endoscopic imaging methods are used in diagnosis. In addition to conservative approaches, endoscopic procedures and laparoscopic or open surgical interventions may be necessary for treatment. Read More

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http://dx.doi.org/10.1155/2018/1259561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831808PMC
January 2018
9 Reads

Flushing Disorders Associated with Gastrointestinal Symptoms: Part 2, Systemic Miscellaneous Conditions.

Clin Med Res 2018 Jun 12;16(1-2):29-36. Epub 2018 Apr 12.

University of Central Florida College of Medicine/HCA, Consortium Graduate Medical Education, North Florida, Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605.

Flushing disorders with involvement of the gastrointestinal tract represent a heterogeneous group of conditions. In part 1 of this review series, neuroendocrine tumors (NET), mast cell activation disorders (MCAD), and hyperbasophilia were discussed. In this section we discuss the remaining flushing disorders which primarily or secondarily involve the gastrointestinal tract. Read More

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http://dx.doi.org/10.3121/cmr.2017.1379bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108508PMC
June 2018
5 Reads

Flushing Disorders Associated with Gastrointestinal Symptoms: Part 1, Neuroendocrine Tumors, Mast Cell Disorders and Hyperbasophila.

Clin Med Res 2018 Jun 12;16(1-2):16-28. Epub 2018 Apr 12.

University of Central Florida College of Medicine/HCA Consortium Graduate Medical Education, North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605.

Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands. Read More

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http://dx.doi.org/10.3121/cmr.2017.1379aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108509PMC
June 2018
7 Reads

Metabolic and nutritional complications of bariatric surgery : a review.

Acta Gastroenterol Belg 2017 Oct-Dec;80(4):515-525

Department of Gastroenterology Erasme University Hospital ULB Brussels, Belgium.

Bariatric surgery is considered as the only effective durable weight-loss therapy and may be curative for obesity-related comorbidities such as diabetes. Nevertheless this surgery is not devoid of potential long-term complications such as dumping syndrome, gastroesophageal reflux disease and nutrient deficiencies. For this reason, preoperative nutritional assessment and rigorous postoperative follow-up with administration of multi-vitamins supplements and assessment of serum levels is recommended for each patient who is undergoing a bariatric surgery. Read More

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May 2018
33 Reads

Indications for total esophagogastric dissociation in children with gastroesophageal reflux disease.

Surg Today 2018 Nov 12;48(11):971-977. Epub 2018 Feb 12.

Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Total esophagogastric dissociation (TED) is used to treat gastroesophageal reflux (GER) after failed fundoplication in neurologically impaired patients. It is now performed for some otherwise healthy patients with severe GER. In this procedure, the gastrointestinal tract is reconstructed in a non-physiological way with a Roux-en-Y esophagojejunal anastomosis and jejuno-jejunostomy. Read More

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http://dx.doi.org/10.1007/s00595-018-1636-9DOI Listing
November 2018
1 Read

Basics of Compounding: Providing Pharmacy Services to Bariatric Surgery Patients.

Int J Pharm Compd 2018 Jan-Feb;22(1):30-39

Indiana University Health, Indianapolis, Indiana.

With the rise in obesity, more individuals are choosing bariatric surgery as a means to successfully lose weight and resolve co-morbidities. These patients need lifelong support from friends, family, and healthcare providers. Pharmacists need to be knowledgeable of the unique needs of these patients in order to provide information and recommendations on drug therapies and supplements. Read More

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May 2018
2 Reads

Post-Fundoplication Dumping Syndrome: A Frequent "Rare" Complication.

ACG Case Rep J 2018 3;5:e1. Epub 2018 Jan 3.

Section of Gastroenterology, Department of Internal Medicine, Temple University Hospital, Philadelphia, PA.

Gastroparesis, caused by delayed emptying of the stomach, has been shown to be associated with Nissen fundoplication. However, symptomatic rapid emptying of the stomach is rare after Nissen fundoplication, and its treatment is often challenging. We report 2 patients with dumping-like syndrome post-fundoplication with marked improvement of symptoms after dietary management and medical treatment. Read More

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http://dx.doi.org/10.14309/crj.2018.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758717PMC
January 2018
6 Reads

Insulinoma presenting with post-prandial hypoglycaemia following fundoplication.

Endocrinol Diabetes Metab Case Rep 2018 18;2018. Epub 2018 Jan 18.

Department of Endocrinology and DiabetesThe Alfred Hospital, Melbourne, Australia.

Insulinomas are rare neuroendocrine tumours that classically present with fasting hypoglycaemia. This case report discusses an uncommon and challenging case of insulinoma soon after upper gastrointestinal surgery. A 63-year-old man presented with 6 months of post-prandial hypoglycaemia beginning after a laparoscopic revision of Toupet fundoplication. Read More

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https://edm.bioscientifica.com/view/journals/edm/2018/1/EDM1
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http://dx.doi.org/10.1530/EDM-17-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777165PMC
January 2018
5 Reads

Experience with FreeStyle Libre Flash glucose monitoring system in management of refractory dumping syndrome in pregnancy shortly after bariatric surgery.

Endocrinol Diabetes Metab Case Rep 2017 12;2017. Epub 2017 Dec 12.

Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Bariatric surgery is an effective therapy for obesity but is associated with long-term complications such as dumping syndromes and nutritional deficiencies. We report a case of a 26-year-old caucasian female, with history of morbid obesity and gestational diabetes (GDM), who became pregnant 4 months after Roux-en-Y bypass surgery. She developed GDM during subsequent pregnancy, which was initially managed with metformin and insulin. Read More

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http://dx.doi.org/10.1530/EDM-17-0128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744619PMC
December 2017
10 Reads

Case 4: Hypoglycemia after Nissen Fundoplication in a 7-month-old Girl.

Pediatr Rev 2018 Jan;39(1):40

Section of Pediatric Endocrinology, Brody School of Medicine, Greenville, NC.

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http://dx.doi.org/10.1542/pir.2015-0144DOI Listing
January 2018
8 Reads

Long-Term Nutritional Outcome and Health Related Quality of Life of Patients Following Esophageal Cancer Surgery: A Meta-Analysis.

Nutr Cancer 2018 Feb-Mar;70(2):192-203. Epub 2017 Dec 27.

c School of Biomedical Sciences , Charles Sturt University , Wagga Wagga , New South Wales , Australia.

Long term health related quality of life (HRQL) and nutritional outcome of patients following esophagectomy for cancer has become increasingly significant as the 5-year survival rate in this patient group is increasing. This meta-analysis aims to investigate the HRQOL, nutritional impact symptoms and nutritional outcomes of patients following an esophagectomy at greater than 12 months after surgery. In studies reporting on HRQL as an outcome, global QOL score at 6-month compare to greater than 12-month showed no statistically significant difference (65. Read More

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http://dx.doi.org/10.1080/01635581.2018.1412471DOI Listing
December 2017
8 Reads

Effectiveness of sitagliptin in a patient with late dumping syndrome after total gastrectomy.

Diabetes Metab Syndr 2018 Apr - Jun;12(2):203-206. Epub 2017 Nov 29.

Department of Diabetes, Osaka City General Hospital, 2-13-22 Miyakojima-hondoori Miyakojima-ku, Osaka City, Osaka, 534-0021, Japan.

An 83-year-old man developed hypoglycemia after undergoing total gastrectomy for gastric cancer in 200X-4. The patient was admitted to our hospital in May 200X and placed on continuous glucose monitoring (CGM). Glycemic excursions were examined while on 3-meal/day (1700kcal) and 6-meal/day (1800kcal) diets. Read More

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http://dx.doi.org/10.1016/j.dsx.2017.11.001DOI Listing
September 2018
2 Reads

Late Dumping Syndrome in a 17-Year-Old Female With Charge Syndrome.

J Paediatr Child Health 2017 Dec;53(12):1244-1245

Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1111/jpc.13724DOI Listing
December 2017
3 Reads

Hyperinsulinemic hypoglycemia after gastric bypass surgery: what's up and what's down?

Int J Obes (Lond) 2017 Oct 13. Epub 2017 Oct 13.

Division of Endocrinology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Obesity is a global public health problem and attempts to treat this condition using life style with and without pharmacological interventions have not been successful in majority of obese individuals. To date, the most effective treatment for obesity is weight loss surgery. One of the most widely used procedures to treat obesity worldwide, Roux-en-Y gastric bypass surgery (RYGB), has shown to induce diabetes remission in addition to significant and sustainable weight loss. Read More

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http://dx.doi.org/10.1038/ijo.2017.257DOI Listing
October 2017
2 Reads

Pasireotide and octreotide in the treatment of severe late dumping syndrome.

Clin Case Rep 2017 10 22;5(10):1608-1611. Epub 2017 Aug 22.

Oxford Centre for Diabetes, Endocrinology and Metabolism Churchill Hospital University of Oxford Oxford UK.

Hypoglycemia due to late dumping is a significant problem postoesophagectomy but may not always be diagnosed sufficiently early. It can be difficult to treat and may severely compromise quality of life. The combination of diazoxide and octreotide or more probably pasireotide may transform the patient's life and should be considered in all problematic cases. Read More

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http://dx.doi.org/10.1002/ccr3.1025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628213PMC
October 2017
11 Reads

Focal Hepatic Glycogenosis in a Patient With Uncontrolled Diabetes Mellitus Type 1.

J Comput Assist Tomogr 2018 Mar/Apr;42(2):230-235

Hepatomegaly and elevated liver enzymes in patients with diabetes are commonly associated with fatty liver disease. However, physicians often forget about another intrinsic substance that can cause a similar clinical picture-glycogen. Liver stores approximately one third of the total body glycogen and is responsible for blood glucose homeostasis. Read More

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http://dx.doi.org/10.1097/RCT.0000000000000673DOI Listing
April 2018
24 Reads

The Effect of Dumping on Weight Loss in Conversion of Failed Restrictive Surgery: a Cross-Sectional Pilot Study.

Obes Surg 2018 03;28(3):665-670

Department of Abdominal Surgery, AZ Delta ziekenhuis, 8800, Roeselare, Belgium.

Purpose: Dumping is currently seen as a negative side effect of Roux-en-Y gastric bypass (RYGB). However, it may help patients to comply with their prescribed diet. In this study, we assess the role of dumping on weight loss in patients who have undergone conversion of failed restrictive surgery into RYGB. Read More

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http://dx.doi.org/10.1007/s11695-017-2906-0DOI Listing
March 2018
3 Reads

Medium-Term Outcomes after Reversal of Roux-en-Y Gastric Bypass.

Obes Surg 2018 03;28(3):781-790

Division of Bariatric Surgery, AZ Sint-Blasius, Kroonveldlaan 50, 9200, Dendermonde, Belgium.

Background: Roux-en-Y gastric bypass (RYGB) can be reversed into normal anatomy (NA) or into sleeve gastrectomy (NASG) to address undesired side effects. Concomitant hiatal hernia repair (HHR) may be required. Before reversal, some patients benefit from placement of a gastrostomy, mostly to predict the result of recreating the native anatomy. Read More

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http://dx.doi.org/10.1007/s11695-017-2928-7DOI Listing
March 2018
1 Read

Incretin Kinetics Before and After Miglitol in Japanese Patients With Late Dumping Syndrome.

J Clin Med Res 2017 Oct 1;9(10):879-885. Epub 2017 Sep 1.

Department of Endocrinology and Metabolism, Yokohama City University School of Medicine, Yokohama, Japan.

Background: In patients with late dumping syndrome following gastrectomy, it has been reported that hypoglycemia occurs due to inhibition of glucagon secretion as a result of excessive insulin production facilitated by an increase in glucagon-like peptide-1 (GLP-1).

Methods: To determine the kinetics of incretins in Japanese patients with late dumping syndrome, an oral glucose tolerance test was carried out before and after miglitol administration, and the kinetics of insulin and incretins were analyzed.

Results: After miglitol administration, there was improvement of hypoglycemia and early phase insulin secretion, with persistent excessive insulin secretion being minimized. Read More

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http://dx.doi.org/10.14740/jocmr3135wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593436PMC
October 2017
12 Reads

Long-term functional outcomes after replacement of the esophagus with gastric, colonic, or jejunal conduits: a systematic literature review.

Dis Esophagus 2017 Dec;30(12):1-11

Department of Upper Abdominal Surgery, Centre for Digestive Diseases, Karolinska University Hospital.

It is generally recognized that in patients with an intact stomach diagnosed with esophageal cancer, gastric tubulization and pull-up shall always be the preferred technique for reconstruction after an esophageal resection. However, in cases with extensive gastroesophageal junction (GEJ) cancer with aboral spread and after previous gastric surgery, alternative methods for reconstruction have to be pursued. Moreover, in benign cases as well as in those with early neoplastic lesions of the esophagus and the GEJ that are associated with long survival, it is basically unclear which conduit should be recommended. Read More

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http://dx.doi.org/10.1093/dote/dox083DOI Listing
December 2017
3 Reads

Etiologies and management of cutaneous flushing: Nonmalignant causes.

J Am Acad Dermatol 2017 Sep;77(3):391-402

Department of Dermatology, Tulane University, New Orleans, Louisiana.

The flushing phenomenon may represent a physiologic or a pathologic reaction. Although flushing is usually benign, it is prudent that the physician remains aware of potentially life-threatening conditions associated with cutaneous flushing. A thorough investigation should be performed if the flushing is atypical or not clearly associated with a benign underlying process. Read More

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http://dx.doi.org/10.1016/j.jaad.2016.12.031DOI Listing
September 2017
11 Reads

[About reduodenization of digestive tract in gastrectomy].

Khirurgiia (Mosk) 2017(8):95-100

Oncology Department, Georgievsky Medical Academy, Simferopol.

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http://dx.doi.org/10.17116/hirurgia2017895-100DOI Listing
December 2017
2 Reads

Oesophageal replacement with stomach: A personal series and review of published experience.

J Paediatr Child Health 2017 Dec 11;53(12):1159-1166. Epub 2017 Aug 11.

Department of Paediatric Surgery, The Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.

Aim: To describe the outcomes of oesophageal replacement using stomach in children.

Methods: All children undergoing oesophageal replacement in a regional centre were prospectively recorded in a customised database and subjected to continual follow up. Complications within 30 days were classified as early, and all other complications were classified as late. Read More

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http://dx.doi.org/10.1111/jpc.13653DOI Listing
December 2017
5 Reads

Diarrhea after bariatric procedures: Diagnosis and therapy.

World J Gastroenterol 2017 Jul;23(26):4689-4700

Yves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.

Diarrhea after bariatric procedures, mainly those with malabsorptive elements including Roux-Y Gastric Bypass and Biliopancreatic Diversion, is common and an essential determinant of quality of life and micro- and macronutrient deficiencies. Bariatric surgery is the only sustainably successful method to address morbid obesity and its comorbidities, particularly gaining more and more importance in the specific treatment of diabetic patients. Approximately half a million procedures are annually performed around the world, with numbers expected to rise drastically in the near future. Read More

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http://dx.doi.org/10.3748/wjg.v23.i26.4689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514634PMC
July 2017
9 Reads

[Multidisciplinary management of dumping syndromes after bariatric surgery].

Rev Med Suisse 2017 Mar;13(555):655-658

Service d'endocrinologie, diabétologie et métabolisme, Consultation de prévention et traitement de l'obésité, CHUV, 1011 Lausanne.

Dumping syndromes are a frequent complication of gastric or bariatric surgery and include early and late dumping. Early dumping is a consequence of rapid delivery of hyperosmolar nutrients into the bowel. Late dumping is the result of a reactive hypoglycemia induced by a hyperinsulinemic response. Read More

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March 2017
3 Reads

Postprandial Hypoglycemia: Complication of Peptic Ulcer Surgery.

Am J Med 2017 12 12;130(12):e527-e529. Epub 2017 Jul 12.

Texas Tech University Health Science Center, Odessa.

Objective: Billroth II procedures (gastrojejunostomy with vagotomy) are seldom performed now but were popular before the advent of histamine 2 receptor blockers and proton pump inhibitors. Such procedures can be a cause of late postprandial hypoglycemia.

Methods: We performed a formal evaluation and discussion of postprandial hypoglycemia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029343173068
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http://dx.doi.org/10.1016/j.amjmed.2017.06.010DOI Listing
December 2017
14 Reads

Roux-en-Y Gastric Bypass Aggravates Vitamin A Deficiency in the Mother-Child Group.

Obes Surg 2018 01;28(1):114-121

Center for Research on Micronutrients (NPqM), Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Objective: The objectives of this study are to compare the nutritional status of vitamin A in women who previously underwent Roux-en-Y gastric bypass (RYGB) who became pregnant or did not, in the same period after surgery, and to assess its effects on mother and child health.

Methodology: A retrospective longitudinal study conducted with women who previously underwent RYGB, paired by age and BMI measured before surgery, divided into group 1 (G1) comprising 77 women who did not become pregnant and group 2 (G2) with 39 women in their third gestational trimester. Both groups were assessed before surgery (T0) and in the same interval after surgery: less than or equal to 1 year (T1) or over 1 year (T2), during a maximum of 2 years. Read More

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http://dx.doi.org/10.1007/s11695-017-2791-6DOI Listing
January 2018
20 Reads

Postprandial hyperinsulinemic hypoglycemia in a child as a late complication of esophageal reconstruction.

J Pediatr Endocrinol Metab 2017 Jul;30(7):791-795

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Background: Postprandial hyperinsulinemic hypoglycemia (PHH) is an increasingly recognized complication of gastric bypass surgery in obese adults, distinct from the "dumping syndrome".

Case Presentation: Upon birth, primary repair of esophageal atresia was performed, and at the age of 14 months definite esophageal reconstruction was performed. At the age of 3 years, recurrent brief episodes of symptomatic hypoglycemia started. Read More

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http://www.degruyter.com/view/j/jpem.2017.30.issue-7/jpem-20
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http://dx.doi.org/10.1515/jpem-2017-0139DOI Listing
July 2017
42 Reads

Nutrient Deficiencies Are Common Prior to Bariatric Surgery.

Nutr Clin Pract 2017 Aug 21;32(4):463-469. Epub 2017 Jun 21.

1 The Johns Hopkins Center for Bariatric Surgery, Baltimore, Maryland, USA.

Obesity, defined as a body mass index >30 kg/m, is a growing worldwide epidemic currently effecting 1 in 10 adults, with rates as high as 40% in the United States. The only proven long-term treatment of severe obesity on a population level is surgical modification of the gastrointestinal anatomy to induce weight loss, termed bariatric surgery. With adequate physician guidance and appropriate candidate criteria, bariatric surgery is an option for effective long-term treatment of obesity and its related comorbidities. Read More

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http://dx.doi.org/10.1177/0884533617712701DOI Listing
August 2017
22 Reads