2,434 results match your criteria Dumping Syndrome


Functional outcome after laparoscopic assisted gastric transposition including pyloric dilatation in long-gap esophageal atresia.

J Pediatr Surg 2020 Jun 13. Epub 2020 Jun 13.

Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital, Tübingen, Germany.

Background/purpose: Among the options for esophageal replacement in long-gap esophageal atresia (LGEA), gastric transposition (GT) is accessible for an endoscopic approach. Here we report a novel technique and functional results after laparoscopic-assisted gastric transposition (LAGT), including pyloric dilatation in patients with LGEA.

Methods: Retrospective analysis of 14 children undergoing LAGT. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.06.004DOI Listing

A comparison between pylorus-preserving and distal gastrectomy in surgical safety and functional benefit with gastric cancer: a systematic review and meta-analysis.

World J Surg Oncol 2020 Jul 8;18(1):160. Epub 2020 Jul 8.

Department of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan Road, Nanjing, 210011, Jiangsu, China.

Background: Due to better functional outcomes, pylorus-preserving gastrectomy (PPG) has been widely applied for early gastric cancer (EGC) patients as an alternative to distal gastrectomy (DG). However, controversies still persist regarding the surgical efficacy and oncological safety of PPG.

Methods: Original studies comparing PPG and DG for EGC were searched in PubMed, Embase, and the Cochrane Register of Controlled Trials up to December 2019. Read More

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http://dx.doi.org/10.1186/s12957-020-01910-yDOI Listing

Isoperistaltic Jejunal Loop Interposition after Total Gastrectomy for Gastric Cancer in Patients with Familial Adenomatous Polyposis.

J Gastric Cancer 2020 Jun 13;20(2):225-231. Epub 2020 Apr 13.

Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Clinica Chirurgica I, Azienda Ospedaliera di Padova, Università di Padova, Padova, Italy.

Gastric cancer is a rare condition affecting patients with familial adenomatous polyposis (FAP). The mainstay of treatment is total gastrectomy. Since duodenal cancer is the most common cause of death after total colectomy in FAP, endoscopic surveillance for duodenal cancer is mandatory. Read More

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http://dx.doi.org/10.5230/jgc.2020.20.e16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311215PMC

[Post-meningitis Dumping Syndrome: A Case Report and Literature Review].

Korean J Gastroenterol 2020 Jun;75(6):347-350

Department of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Dumping syndrome has long been associated with gastric surgery. The authors experienced an adult patient presenting with dumping syndrome after meningitis without any previous surgical procedures on the stomach and small bowel. Dysfunction of the autonomic nervous system after infective meningitis may originate from postinfectious sequelae or an immunologic mechanism. Read More

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http://dx.doi.org/10.4166/kjg.2020.75.6.347DOI Listing

Early experience with a nutrition and survivorship clinic in esophageal cancer.

Dis Esophagus 2020 Jun 22. Epub 2020 Jun 22.

National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.

Improved cure rates in esophageal cancer care have increased focus on health-related quality of life (HRQL) in survivorship. To optimize recovery after esophagectomy, particularly nutritional well-being, a personalized multidisciplinary survivorship clinic was established at this center. Assessments at 6 and 12 months postoperatively include validated European Organization for the Research and Treatment of Cancer (EORTC) symptom and health-related quality of life (HRQL) questionnaires, functional status review, anthropometry, and biochemical screening for micronutrient deficiencies. Read More

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http://dx.doi.org/10.1093/dote/doaa061DOI Listing

Follow-up after bariatric surgery: A review.

Nutrition 2020 Apr 21;78:110831. Epub 2020 Apr 21.

Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania; 1st Surgery Department, Constanta County Emergency Hospital, Constanta, Romania.

Bariatric surgery is becoming increasingly popular in the treatment of severely obese patients who failed to lose weight with the help of non-surgical interventions. Such patients are at increased risk for premature death, type 2 diabetes, high blood pressure, gallstones, coronary heart disease, dyslipidemia, some cancers, anxiety, depression, and degenerative joint disorders. Although bariatric surgery appears to be the most effective and durable treatment option for obesity, it is associated with a number of surgical and medical complications. Read More

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http://dx.doi.org/10.1016/j.nut.2020.110831DOI Listing
April 2020
2.926 Impact Factor

Endoscopic toxin as a treatment for delayed gastric emptying following oesophagogastrectomy.

Ann R Coll Surg Engl 2020 Jun 15:1-4. Epub 2020 Jun 15.

Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK.

Introduction: The incidence of delayed gastric emptying (DGE) following oesophagogastrectomy with gastric conduit reconstruction is reported to be between 1.7% and 50%. This variation is due to differing practices of intraoperative pylorus drainage procedures, which increase the risk of postoperative biliary reflux and dumping syndrome, resulting in significant morbidity. Read More

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http://dx.doi.org/10.1308/rcsann.2020.0136DOI Listing

International consensus on the diagnosis and management of dumping syndrome.

Nat Rev Endocrinol 2020 Aug 26;16(8):448-466. Epub 2020 May 26.

Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (ChroMetA), Catholic University of Leuven, Leuven, Belgium.

Dumping syndrome is a common but underdiagnosed complication of gastric and oesophageal surgery. We initiated a Delphi consensus process with international multidisciplinary experts. We defined the scope, proposed statements and searched electronic databases to survey the literature. Read More

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http://dx.doi.org/10.1038/s41574-020-0357-5DOI Listing

Outcome of revisional bariatric surgery for insufficient weight loss after laparoscopic Roux-en-Y gastric bypass: an observational study.

Surg Obes Relat Dis 2020 Apr 18. Epub 2020 Apr 18.

University Center for Gastrointestinal and Liver Diseases, St. Claraspital and University Hospital Basel, Basel, Switzerland. Electronic address:

Background: Insufficient weight loss or secondary weight regain with or without recurrence of comorbidity can occur years after laparoscopic Roux en Y gastric bypass (LRYGB). In selected patients, increasing restriction or adding malabsorption may be a surgical option after conservative measures failed.

Objectives: Evaluation of short and long term results of revisional surgery for insufficient weight loss or weight regain after LRYGB. Read More

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http://dx.doi.org/10.1016/j.soard.2020.04.009DOI Listing

Alcohol and gastric motility: pathophysiological and therapeutic implications.

J Investig Med 2020 Jun 23;68(5):965-971. Epub 2020 May 23.

Gastroenterology, Texas Tech University Health Sciences Center El Paso, El Paso, Texas, USA.

Alcohol has been associated with alterations in gastric motility. The literature identifies that various factors play a role in alcohol's effect on gastric emptying including differences in alcohol concentration, osmolarity, caloric content, amino acids as well as different processing techniques (fermentation vs distillation). Additionally, chronic alcohol consumption has been shown to alter the myenteric nitrergic system resulting in impaired gastrointestinal motor function, and it also has an inhibitory effect on the release of several neurotransmitters that play a key role in gastrointestinal motility, including acetylcholine. Read More

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http://dx.doi.org/10.1136/jim-2020-001327DOI Listing

Frequency of Abnormal Glucose Tolerance Test Suggestive of Dumping Syndrome Following Oesophageal Atresia Repair.

J Pediatr Gastroenterol Nutr 2020 Jun;70(6):820-824

This work is dedicated in memoriam of Dr Laurent Michaud.

Objectives: Dumping syndrome (DS) is mostly described as a complication of antireflux surgery in oesophageal atresia (OA) but we previously reported 2 cases of DS before any other surgery in infants operated at birth for OA. The objectives of the present study were to assess the prevalence of abnormal oral glucose tolerance test (OGTT) at 3 months of age in infants operated at birth with type C OA, to describe symptoms and clinical features, and to assess risk factors in infants presenting with abnormal OGTT suggestive of DS.

Methods: A prospective case series study including infants with type C OA without fundoplication, born between 2013 and 2016 in 8 centres was conducted. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002651DOI Listing

Gastric pull-up by the retrosternal route for esophageal replacement: Feasibility in a limited-resource scenario.

J Pediatr Surg 2020 Apr 28. Epub 2020 Apr 28.

All India Institute of Medical Sciences, New Delhi, India, PIN 110029. Electronic address:

Objectives: The authors herein report the results of esophageal replacement by gastric pull-up technique through the retrosternal route as an option for esophageal replacement in a resource-constrained setup.

Method: Prospectively collected data upon twenty-two consecutive patients (male:female = 17:5) with mean age 24.9 months (7 months-12 years) and mean weight 7. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.04.017DOI Listing

Effectiveness of a comprehensive post-operative health education program in improving quality of life after gastric cancer surgery.

Ann Palliat Med 2020 May 21;9(3):921-926. Epub 2020 Apr 21.

Second Ward, Department of Colorectal Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.

Background: Patients with gastric cancer often experience postoperative problems such as dumping syndrome, abdominal cramps, and nausea, which have profound effects on their mental health and quality of life. Earlier studies have shown that comprehensive health education can dramatically improve the quality of life of cancer patients after surgery. Thus, in this study, we conducted a health education intervention program in patients who had undergone surgical treatment for gastric cancer and evaluated the effectiveness of this program in improving the postoperative quality of life, with an attempt to offer evidence for better postoperative management of gastric cancer patients. Read More

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http://dx.doi.org/10.21037/apm.2020.04.14DOI Listing

[Which management of pregnancy after bariatric surgery?]

Gynecol Obstet Fertil Senol 2020 May 6. Epub 2020 May 6.

Service de gynécologie-obstétrique, centre hospitalier intercommunal de Poissy Saint-Germain, Poissy, France; UVSQ, INRAE, BREED, université Paris-Saclay, 78350 Jouy-en-Josas, France; BREED, école nationale vétérinaire d'Alfort, 94700 Maisons-Alfort, France. Electronic address:

Obesity represents a major public health issue and a potential threat for people health. Moreover, the incidence of obesity has been increasing and therefore, the incidence of women with an history of bariatric surgery with a pregnancy desire has been also increased. Although the weight loss after bariatric surgery has positive effects on pregnancy outcomes, these surgical procedures may be associated with adverse outcomes as well, for example micronutrient deficiencies, dumping syndrome, surgical complications such as internal hernias, and obstetrical complications such as small for gestational age as instance. Read More

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http://dx.doi.org/10.1016/j.gofs.2020.04.015DOI Listing

All People.

Authors:
Greg Kaebnick

Hastings Cent Rep 2020 03;50(2)

In early March 2020, the March-April Hastings Center Report was very nearly assembled and contained nothing about Covid-19, which was still just beginning to make itself publicly known in the United States. Two weeks later, the editorial line-up was undergoing a remix, and essays that lay out sweeping agendas for the response to the worldwide crisis were in preparation. The central theme in the agenda that Lawrence O. Read More

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http://dx.doi.org/10.1002/hast.1092DOI Listing

Functional and nutritional outcomes after gastric cancer surgery.

Transl Gastroenterol Hepatol 2020 5;5:29. Epub 2020 Apr 5.

Department of Surgery, Saiseikai Shiga Hospital, Ritto City, Japan.

Recent improvements in diagnostic techniques and national screening programs have resulted in increasing number of patients diagnosed with early gastric cancer (EGC). The low incidence rate of lymph node metastasis and excellent survival rates after surgical treatment for EGC enabled the reduction in the extent of lymphadenectomy and the range of gastric resection for function-preserving gastrectomy. Thus, the quality of life (QOL) of patients with gastric cancer (GC) in the curative stage can be maintained. Read More

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http://dx.doi.org/10.21037/tgh.2019.11.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063493PMC

14 Years' experience of esophageal replacement surgeries.

Pediatr Surg Int 2020 Jul 31;36(7):835-841. Epub 2020 Mar 31.

The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.

Background: Esophageal replacement is a challenge to the therapeutic skills of surgeons and a technically demanding operation in the pediatric age group. Various conduits and routes have been described in the literature, each with their specific advantages and disadvantages. We carried out this retrospective study to share our experience of esophageal replacement. Read More

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http://dx.doi.org/10.1007/s00383-020-04649-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223057PMC
July 2020
1.061 Impact Factor

A Case Report of Hypoglycemia Due to Late Dumping Syndrome After Jejunostomy Tube Insertion.

Cureus 2020 Feb 6;12(2):e6897. Epub 2020 Feb 6.

Internal Medicine, Alfaisal University, Riyadh, SAU.

Dumping syndrome occurs when food moves to the small bowel faster than usual. Patients can report a variety of symptoms such as abdominal cramps, weakness, flushing, shakiness, and decreased consciousness. Dumping syndrome can be divided into early and late based on the onset of the symptoms after the ingestion of a meal. Read More

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http://dx.doi.org/10.7759/cureus.6897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059873PMC
February 2020

In Search of the Optimal Reconstruction Method after Total Gastrectomy. Is Roux-en-Y the Best? A Review of the Randomized Clinical Trials.

Chirurgia (Bucur) 2020 Jan-Feb;115(1):12-22

Numerous procedures for reconstruction after total gastrectomy have been proposed in order to achieve the lowest postoperative morbidity. Roux-en-Y esojejunostomy is widely accepted as a standard reconstruction technique due to its simplicity and its satisfactory nutritional outcomes. The construction of a gastric pouch and the maintenance of the duodenal transit have been proposed to ameliorate the quality of life of patients with gastric cancer. Read More

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http://dx.doi.org/10.21614/chirurgia.115.1.12DOI Listing

Surgical management of gastric adenocarcinoma. Official expert recommendations delivered under the aegis of the French Association of Surgery (AFC).

J Visc Surg 2020 Apr 6;157(2):117-126. Epub 2020 Mar 6.

Digestive surgery Department, Medico-chirurgical Center Magellan, avenue de Magellan, 33604 Pessac, France. Electronic address:

Gastric adenocarcinoma (GA) is the 5 most common cancer in the world; in France, however, its incidence has been steadily decreasing. Twenty-five experts brought together under the aegis of the French Association of Surgery collaborated in the drafting of a series of recommendations for surgical management of GA. As concerns preoperative evaluation and work-up, echo-endoscopy aimed at clarifying lymph node status should be performed in all candidates for surgical resection and exploratory laparoscopy in cases of GA cT3/T4 and/or N+ for peritoneal carcinomatosis. Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2020.02.006DOI Listing

Somatostatin Analogs in Clinical Practice: a Review.

Int J Mol Sci 2020 Feb 29;21(5). Epub 2020 Feb 29.

Department of Endocrinology, "La Paz" University Hospital. Paseo de la Castellana, 261, 28046 Madrid, Spain.

Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of somatotropinomas, thyrotropinomas, and functioning and non-functioning gastroenteropancreatic neuroendocrine tumors. They should also be considered an effective and safe therapeutic alternative to corticotropinomas, gonadotropinomas, and prolactinomas resistant to dopamine agonists. Somatostatin analogs have also shown to be useful in the treatment of other endocrine diseases (congenital hyperinsulinism, Graves' orbitopathy, diabetic retinopathy, diabetic macular edema), non-endocrine tumors (breast, colon, prostate, lung, and hepatocellular), and digestive diseases (chronic refractory diarrhea, hepatorenal polycystosis, gastrointestinal hemorrhage, dumping syndrome, and intestinal fistula). Read More

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http://dx.doi.org/10.3390/ijms21051682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084228PMC
February 2020

Endoscopic management of dumping syndrome after Roux-en-Y gastric bypass: a large international series and proposed management strategy.

Gastrointest Endosc 2020 Jul 26;92(1):91-96. Epub 2020 Feb 26.

Department of Endocrinology, University Hospital, Würzburg, Germany.

Background And Aims: Roux-en-Y gastric bypass (RYGB) is refractory to lifestyle and pharmacotherapy measures, requiring reversal of the patient's bariatric surgery. Reversal can lead to weight regain and recrudescence of their comorbidities. Our aim was to report a multicenter experience on the endoscopic management of refractory dumping syndrome with endoscopic transoral outlet reduction (TORe). Read More

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http://dx.doi.org/10.1016/j.gie.2020.02.029DOI Listing
July 2020
5.369 Impact Factor

Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome.

Pediatr Neurol 2020 04 26;105:65-66. Epub 2019 Dec 26.

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2019.12.002DOI Listing

Utility of continuous glucose monitoring following gastrectomy.

Gastric Cancer 2020 Jul 8;23(4):699-706. Epub 2020 Jan 8.

Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

Background: Glucose fluctuation after gastrectomy represented by dumping syndrome is a well-known post-gastrectomy syndrome that negatively impacts patient quality of life. However, the current methods of post-gastrectomy glucose monitoring do not comprehensively capture the postoperative blood glucose fluctuations that characterize this.

Methods: We used a continuous glucose monitoring (CGM) system to document the glycemic profiles of patients undergoing gastrectomy and compared these between patients undergoing distal gastrectomy (DG) and total gastrectomy (TG). Read More

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http://dx.doi.org/10.1007/s10120-019-01036-5DOI Listing

Review of the management of diarrhea syndrome after a bariatric surgery.

Endocrinol Diabetes Nutr 2020 Jun - Jul;67(6):401-407. Epub 2019 Dec 13.

Unidad de Gastroenterología, Servicio de Aparato Digestivo, Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Barcelona, España.

Obesity is a prevalent health problem in our population. Bariatric surgery is the indicated treatment for severe cases. It is very effective (together with an adequate lifestyle modification) but it is also associated with frequent adverse events. Read More

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http://dx.doi.org/10.1016/j.endinu.2019.09.013DOI Listing
December 2019

Gastrointestinal Motility Issues in Cancer Patients.

Authors:
Mehnaz A Shafi

Curr Gastroenterol Rep 2019 Dec 10;21(12):69. Epub 2019 Dec 10.

University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1466, Houston, TX, 77030, USA.

Purpose Of Review: This paper seeks to highlight GI motility disorders that are frequently present in patients with a malignancy. GI dysmotility can occur due to the cancer itself or as a consequence of medical and surgical treatments. Often, symptoms are nonspecific and the diagnosis requires a high index of suspicion. Read More

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http://dx.doi.org/10.1007/s11894-019-0738-xDOI Listing
December 2019

Comparison of three digestive tract reconstruction methods for the treatment of Siewert II and III adenocarcinoma of esophagogastric junction: a prospective, randomized controlled study.

World J Surg Oncol 2019 Dec 6;17(1):209. Epub 2019 Dec 6.

Department of Minimal Invasive Digestive Surgery, Shanxi Tumor Hospital, Shanxi Medical University, Taiyuan, 030013, China.

Background: The incidence of adenocarcinoma of esophagogastric junction (AEG) has recently risen worldwide, including in Eastern Asia. The aim of the study was to explore the short-term and long-term clinical efficacy of piggyback jejunal interposition reconstruction single-tract reconstruction (PJIRSTR), piggyback jejunal interposition reconstruction double-tract reconstruction (PJIRDTR), and total gastrectomy esophageal jejunal Roux-en-Y anastomosis (TGRY) for the treatment of Siewert II and III AEG patients.

Methods: A total of 300 Siewert II and III AEG patients admitted to Shanxi Tumor Hospital from June 2015 to December 2017 were prospectively selected. Read More

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http://dx.doi.org/10.1186/s12957-019-1762-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898954PMC
December 2019

One Anastomosis Gastric Bypass-Mini-Gastric Bypass (OAGB-MGB) Versus Roux-en-Y Gastric Bypass (RYGB)-a Mid-Term Cohort Study with 612 Patients.

Obes Surg 2020 Apr;30(4):1230-1240

Department of General, Visceral and Transplant Surgery, RWTH Aachen University, Aachen, Germany.

Background: OAGB-MGB emerged as a standard procedure, albeit RYGB remains the most frequently performed gastric bypass. Comparative studies are scarce.

Methods: Prospectively collected data (July 2006 to November 2017) from a large sample size and adequate follow-up were analyzed using logistic regression and linear mixed models. Read More

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http://dx.doi.org/10.1007/s11695-019-04250-3DOI Listing

Efficacy and safety of lanreotide in postoperative dumping syndrome: A Phase II randomised and placebo-controlled study.

United European Gastroenterol J 2019 10 27;7(8):1064-1072. Epub 2019 Jun 27.

Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.

Background: Data on the efficacy and safety of the long-acting somatostatin analogue lanreotide (LAN) for postoperative dumping syndrome are lacking.

Objective: We performed a double-blind, randomised and placebo-controlled crossover study of LAN Autogel® 90 mg in postoperative dumping.

Methods: Adults with a positive prolonged oral glucose tolerance test or spontaneous hypoglycaemia and total dumping score (DS) ≥ 10 despite dietary measures were treated with three monthly injections of LAN or placebo in a randomised crossover fashion with an eight-week wash-out period. Read More

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http://dx.doi.org/10.1177/2050640619862166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794701PMC
October 2019

Bariatric Surgery and Its Complications in Inflammatory Bowel Disease Patients.

Inflamm Bowel Dis 2019 Oct 18. Epub 2019 Oct 18.

Department of Gastroenterology, Hepatology & Nutrition, Center for Human Nutrition, Center for Gut Rehabilitation and Intestinal Transplantation, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Recent data have suggested that bariatric procedures, especially laparoscopic sleeve gastrectomy (SG), are safe and effective weight loss measures in patients with inflammatory bowel disease (IBD). But most of the studies have looked at short-term outcomes, and there is a general lack of awareness of underlying disease processes and baseline comorbidities in IBD patients undergoing bariatric procedures. Postbariatric issues in IBD patients including diarrhea from dumping syndrome, choleretic diarrhea, a high prevalence of small intestinal bacterial overgrowth, gastroesophageal reflux disease, Barrett's esophagus, stomal ulcerations, stenosis, and renal and gallstones can complicate the natural history of IBD. Read More

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https://academic.oup.com/ibdjournal/advance-article/doi/10.1
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http://dx.doi.org/10.1093/ibd/izz246DOI Listing
October 2019
5 Reads

Short-term outcomes of endoscopic gastro-jejunal revisions for treatment of dumping syndrome after Roux-En-Y gastric bypass.

Surg Endosc 2020 Aug 24;34(8):3626-3632. Epub 2019 Sep 24.

Department of Visceral Surgery, Hirslanden Clinic Beau-Site, Schaenzlihalde 1, 3013, Berne, Switzerland.

Background: Dumping syndrome is a known long-term complication of Roux-en-Y gastric bypass (RYGB). Most cases can be avoided with dietary and lifestyle changes. Severe dumping is characterized by multiple daily episodes with significant impact on quality-of-life. Read More

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http://dx.doi.org/10.1007/s00464-019-07137-7DOI Listing
August 2020
1 Read

Herbal Medicine for Dumping Syndrome: A Systematic Review and Meta-Analysis.

Integr Cancer Ther 2019 Jan-Dec;18:1534735419873404

Dongguk University, Seoul, Republic of Korea.

Dumping syndrome is a common complication of surgical treatment of gastric cancer, but conventional therapy has limitations related to symptom care due to its structural cause and the decreased quality of life. The objective of this review was to assess the clinical evidence for the effectiveness of herbal medicine as a treatment for dumping syndrome. A literature review was conducted using 16 databases from their inceptions to March 2018. Read More

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http://dx.doi.org/10.1177/1534735419873404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759702PMC
March 2020
1 Read

[Long-term management after bariatric surgery].

Rev Med Suisse 2019 Aug;15(659):1458-1460

Service de diabétologie, maladies métaboliques et nutrition, CHU Liège, 4000 Liège, Belgique.

The number of bariatric surgery interventions has increased over the past 10 years. The effectiveness of bariatric surgery is currently well demonstrated. However, the need to organize a careful medical follow-up of these patients is essential to ensure a positive evolution over the long term. Read More

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August 2019
3 Reads

Prevalence and risk factors for symptoms suggestive of hypoglycemia and early dumping syndrome after sleeve gastrectomy.

Surg Obes Relat Dis 2019 Sep 29;15(9):1439-1446. Epub 2019 Jun 29.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

Background: Postprandial hypoglycemia and early dumping syndrome are common complications after bariatric surgery. Although sleeve gastrectomy (SG) has become a primary option for many bariatric surgeons, limited information was available for the prevalence and risk factors of the complications.

Objective: To assess the prevalence and possible risk factors for postprandial hypoglycemia and early dumping syndrome based on self-reported symptoms of SG patients. Read More

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http://dx.doi.org/10.1016/j.soard.2019.06.026DOI Listing
September 2019
6 Reads

Dumping Syndrome: A Rare Complication Following Nissen Fundoplication.

Eur J Case Rep Intern Med 2019 10;6(7):001177. Epub 2019 Jul 10.

Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Dumping syndrome (DS) is a debilitating entity with gastrointestinal and vasomotor symptoms due to rapid gastric emptying. It is a rare complication of Nissen fundoplication in adults. We report the case of a patient with oesophageal compressive symptoms (dysphagia, oesophageal food impaction and regurgitation) and frequent episodes of sweating and hypoglycaemia after a Nissen fundoplication to treat gastroesophageal reflux disease. Read More

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https://www.ejcrim.com/index.php/EJCRIM/article/view/1177
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http://dx.doi.org/10.12890/2019_001177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663054PMC
July 2019
4 Reads

Gastroparesis and Dumping Syndrome: Current Concepts and Management.

J Clin Med 2019 Jul 29;8(8). Epub 2019 Jul 29.

Department of Gastroenterology and Hepatology, University Hospital Zurich, CH-8091 Zurich, Switzerland.

Gastroparesis and dumping syndrome both evolve from a disturbed gastric emptying mechanism. Although gastroparesis results from delayed gastric emptying and dumping syndrome from accelerated emptying of the stomach, the two entities share several similarities among which are an underestimated prevalence, considerable impairment of quality of life, the need for a multidisciplinary team setting, and a step-up treatment approach. In the following review, we will present an overview of the most important clinical aspects of gastroparesis and dumping syndrome including epidemiology, pathophysiology, presentation, and diagnostics. Read More

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http://dx.doi.org/10.3390/jcm8081127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723467PMC
July 2019
3 Reads

Endoscopic Gastrojejunal Revision (Transoral Outlet Reduction) for Persistent Hypoglycemia After Gastric Bypass.

Obes Surg 2019 11;29(11):3773-3775

Department of Surgery, NorthShore University HealthSystem, Evanston, IL, 60201, USA.

Background: The patient presented with symptomatic postprandial biweekly hypoglycemic seizures. Her hypoglycemic episodes were aggravated by stress and also occurred during sleep. She managed these hypoglycemic episodes with an endocrinologist, trying both nutritional and medical management without successful control of her symptoms. Read More

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http://dx.doi.org/10.1007/s11695-019-04113-xDOI Listing
November 2019
3 Reads

Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A.

FASEB J 2019 10 12;33(10):11247-11257. Epub 2019 Jul 12.

Department of Medicine and Physiology, University of California, San Francisco, San Francisco, California, USA.

Interstitial cells of Cajal, which express the calcium-activated chloride channel transmembrane member 16A (TMEM16A), are an important determinant of gastrointestinal (GI) motility. We previously identified the acylaminocycloalkylthiophene class of TMEM16A inhibitors, which, following medicinal chemistry, gave analog 2-bromodifluoroacetylamino-5,6,7,8-tetrahydro-4-cyclohepta[]thiophene-3-carboxylic acid -tolylamide (TM-23) with 30 nM half-maximal inhibitory concentration. Here, we tested the efficacy of TM-23 for inhibition of GI motility in mice. Read More

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http://dx.doi.org/10.1096/fj.201900858RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766656PMC
October 2019
4 Reads

Gastrostomy Placement and Management in Children: A Single-Center Experience.

Nutrients 2019 Jul 10;11(7). Epub 2019 Jul 10.

Department of Paediatric Surgery, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, via dell'Istria 65/1, 34137 Trieste, Italy.

Background: To prevent malnutrition and food aspiration in children with chronic neuromuscular problems, enteral nutrition provided by gastrostomy is recommended. Long-term follow-up data about surgical and medical complications of PEG are available, but few papers have addressed all of the issues in the same series.

Methods: This retrospective study enrolled patients under 18 years who had a gastrostomy tube placed at our institution between 2003 and 2017. Read More

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http://dx.doi.org/10.3390/nu11071555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683077PMC
July 2019
9 Reads

Pregnancy after 24 Postoperative Months of Roux-En-Y Gastric Bypass Presents Risk of Pregnancy Complications Similar to Pregnancy within the First Postoperative Year.

Ann Nutr Metab 2019 9;75(1):24-30. Epub 2019 Jul 9.

Doctor of Science from ENSP/FIOCRUZ, Full Professor of the Department of Social and Applied Nutrition of the Institute of Nutrition at UFRJ, Coordinator of the Center for Research on Micronutrients (NPqM) of the Institute of Nutrition Josué de Castro of UFRJ, Rio de Janeiro, Brazil.

Background: To assess the influence of the time interval between pregnancy and the Roux-en-Y gastric bypass (RYGB) on maternal-infant complications.

Methods: This is an analytical, longitudinal and retrospective study comprising 42 pregnant women who had previously undergone RYGB, subdivided according to the time interval between pregnancy and bariatric surgery: ≤12 months (G1), >12 and <24 months (G2) and ≥24 months (G3). Anthropometric variables of mothers, newborns and information on pregnancy complications were collected. Read More

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http://dx.doi.org/10.1159/000501423DOI Listing
June 2020
5 Reads

Diazoxide for the Treatment of Hypoglycemia Resulting From Dumping Syndrome in a Child.

J Endocr Soc 2019 Jul 5;3(7):1357-1360. Epub 2019 Jun 5.

Division of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.

Dumping syndrome-associated hypoglycemia is caused by an exaggerated hyperinsulinemic response to glucose absorption in the small intestine. Diazoxide acts on the ATP-sensitive potassium channels and prevents insulin secretion and, thus, should be beneficial for the treatment of hypoglycemia secondary to dumping syndrome. We report on the efficacy of diazoxide in a pediatric patient with dumping syndrome. Read More

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http://dx.doi.org/10.1210/js.2019-00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608547PMC
July 2019
5 Reads

Crohn's Disease of the Esophagus, Duodenum, and Stomach.

Clin Colon Rectal Surg 2019 Jul 17;32(4):231-242. Epub 2019 Jun 17.

Division of Colon and Rectal Surgery, New York University Langone Medical Center, New York, New York.

Upper gastrointestinal Crohn's is an under-reported, under-recognized phenotype of Crohn's disease. Routine screening in the pediatric population has shown a higher prevalence compared with adults; however, most adult patients remain asymptomatic with respect to upper gastrointestinal Crohn's disease. For the patients who are symptomatic, medical treatment is the first line of management, except for cases of obstruction, perforation, or bleeding. Read More

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http://dx.doi.org/10.1055/s-0039-1683850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606321PMC
July 2019
7 Reads

Time to Dump Late Dumping Syndrome Terminology.

Obes Surg 2019 09;29(9):2985-2986

University of Colorado, Division of Endocrinology, Metabolism, and Diabetes, 12801 E. 17th Ave., MS 8106, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s11695-019-04033-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008495PMC
September 2019
18 Reads

Gastric Emptying Improved Significantly After PRG Compared to Billroth-I Reconstruction: Assessment of Gastric Emptying With a C-Breath Test.

Anticancer Res 2019 Jun;39(6):3227-3230

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Background: We advocated the usefulness of pylorus-reconstruction gastrectomy (PRG) to improve quality of life following surgery for gastric cancer. The current study assessed gastric emptying following PRG in comparison with those who underwent conventional Billroth-I (B-I) reconstruction and in healthy controls using a C breath test.

Patients And Methods: The study group consisted of 24 patients who underwent PRG from September 20, 2007 to July 26, 2012 at the Department of Surgery at Daisan Hospital (affiliated with The Jikei University School of Medicine). Read More

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http://dx.doi.org/10.21873/anticanres.13463DOI Listing
June 2019
17 Reads

Late dumping syndrome in an infant on feeding jejunostomy.

BMJ Case Rep 2019 May 21;12(5). Epub 2019 May 21.

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

This article presents the case of a 3-month-old male child, who while on bolus jejunostomy tube feeds, developed recurrent episodes of hypoglycaemia. This infant had presented with failure to thrive with moderate gastroesophageal reflux necessitating a feeding jejunostomy. The infant was started on bolus feeds through the jejunostomy tube but developed recurrent episodes of hypoglycaemia. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22847
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http://dx.doi.org/10.1136/bcr-2018-228471DOI Listing
May 2019
16 Reads

Pouch Versus No Pouch Following Total Gastrectomy: Meta-analysis of Randomized and Non-randomized Studies.

Ann Surg 2019 06;269(6):1041-1053

Department of Surgery, University Surgical Cluster, National University Health System, Singapore.

Objective: The aim of the study was to assess the impact of pouch reconstruction on perioperative outcomes, postprandial symptoms, nutritional and anthropometric parameters, and overall quality of life after total gastrectomy for gastric malignancy.

Summary Background Data: The short-term perioperative risks and longer term functional value of creating a small-bowel reservoir after total gastrectomy are contended.

Methods: A search for randomized and non-randomized studies comparing reconstruction with or without a pouch was conducted. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003082DOI Listing
June 2019
12 Reads
8.327 Impact Factor

Comparison of the dietary intake amongst women in the late postoperative period after Roux-en-Y gastric bypass with the bariatric food pyramidof dietary intake with reference values among women in late postoperative of y-en-roux gastric bypass.

Nutr Hosp 2019 Jul;36(3):599-603

Universidade Federal do Paraná.

Introduction: Introduction: the Roux-en-Y gastric bypass (RYGB) is considered to be an efficient treatment of obesity. There is an improvement in the dietary intake in the immediate postoperative period, but after the first year there is a tendency to return to the old pre-surgery habits. The objective of the present study was to compare the dietary intake of women in the late postoperative period after RYGB with the recommendations of the specific bariatric food pyramid. Read More

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http://dx.doi.org/10.20960/nh.2340DOI Listing
July 2019
8 Reads

Heterogeneity in the Definition and Clinical Characteristics of Dumping Syndrome: a Review of the Literature.

Obes Surg 2019 06;29(6):1984-1989

Department of Abdominal Surgery, University Hospital Antwerp, Edegem, Belgium.

Background: No real consensus regarding the definition of dumping syndrome (DS) seems to exist and few subtyping is used in clinical practice. Knowledge is needed for correct design of trials and establishment of uniform treatment strategies. The aim of this study is to explore the distribution of clinical characteristics related to the subtypes of DS. Read More

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http://link.springer.com/10.1007/s11695-019-03818-3
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http://dx.doi.org/10.1007/s11695-019-03818-3DOI Listing
June 2019
27 Reads

A Real-World, Insurance-Based Algorithm Using the Two-Fold Running Suture Technique for Transoral Outlet Reduction for Weight Regain and Dumping Syndrome After Roux-En-Y Gastric Bypass.

Obes Surg 2019 07;29(7):2225-2232

Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Background And Aims: Transoral outlet reduction (TORe) by devitalization and/or endoscopic suturing (ES) has been implemented in the management of weight regain post-RYGB. This study aims to assess the efficacy and safety of TORe following an insurance-based algorithm.

Methods: A prospectively maintained database of patients who underwent TORe between September 2015 and January 2018 at a single academic center was reviewed. Read More

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http://dx.doi.org/10.1007/s11695-019-03828-1DOI Listing
July 2019
12 Reads