[Research progression of the relationship between integrin α2β1 and drug-induced gingival overgrowth].
Hua Xi Kou Qiang Yi Xue Za Zhi 2017 Feb;35(1):99-103
State Key Laboratory of Oral Diseases, Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Drug-induced gingival overgrowth (DIGO) is characterized by fibrous gingival hyperplasia and increased gingival volume. DIGO is histologically associated with proliferation of cells and deposition of extracellular matrices, particularly collagen. Integrin α2β1 is related to collagen phagocytosis and involved in the occurrence and progression of DIGO. Read More