Int J Mol Sci 2016 Dec 18;17(12). Epub 2016 Dec 18.
Dermatology Department, Royal North Shore Hospital, 2065 Sydney, Australia.
Toxic epidermal necrolysis (TEN) is a rare but life threatening mucocutaneous reaction to drugs or their metabolites. It is characterised by widespread keratinocyte apoptosis and sloughing of the skin, erosions of the mucous membranes, painful blistering, and severe systemic disturbance. The pathophysiology of TEN is incompletely understood. Read More