7,379 results match your criteria Drug and Alcohol Dependence[Journal]


Corrigendum to "Fentanyl and heroin contained in seized illicit drugs and overdose-related deaths in British Columbia, Canada: An observational analysis" [Drug Alcohol Depend. 185 (2018) 322-327].

Drug Alcohol Depend 2019 Feb 14;197:48. Epub 2019 Feb 14.

Department of Family Practice, University of British Columbia, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2019.02.001DOI Listing
February 2019

Prenatal alcohol exposure and facial morphology in a UK cohort.

Drug Alcohol Depend 2019 Feb 5;197:42-47. Epub 2019 Feb 5.

MRC Integrative Epidemiology Unit, Population Health Sciences, Oakfield House, Oakfield Grove, University of Bristol, BS8 2BN, UK; Bristol Dental School, University of Bristol, UK. Electronic address:

Background: High levels of prenatal alcohol exposure are known to cause an array of adverse outcomes including fetal alcohol syndrome (FAS); however, the effects of low to moderate exposure are less-well characterized. Previous findings suggest that differences in normal-range facial morphology may be a marker for alcohol exposure and related adverse effects.

Methods: In the Avon Longitudinal Study of Parents and Children, we tested for an association between maternal alcohol consumption and six FAS-related facial phenotypes in their offspring, using both self-report questionnaires and the maternal genotype at rs1229984 in ADH1B as measures of maternal alcohol consumption. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.031DOI Listing
February 2019

Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment.

Drug Alcohol Depend 2019 Jan 17;197:37-41. Epub 2019 Jan 17.

Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Child Study Center, Yale School of Medicine, New Haven, CT, USA; APT Foundation, New Haven, CT, USA.

Background: Although smoking is prevalent among populations with opioid use disorder (OUD), few studies have examined electronic cigarette (EC) use in individuals seeking opioid agonist therapy (OAT). The aim of this study was to evaluate the prevalence and correlates of EC use among individuals seeking OAT.

Methods: 782 patients seeking OAT for OUD completed surveys assessing current and past EC use, reasons for use, current and past cigarette smoking, nicotine dependence, psychiatric distress, trauma, and pain. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.012DOI Listing
January 2019

Integrated cognitive behavioral therapy for ADHD in adult substance use disorder patients: Results of a randomized clinical trial.

Drug Alcohol Depend 2019 Feb 5;197:28-36. Epub 2019 Feb 5.

Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background: Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occurs with Substance Use Disorders (SUDs). Standard ADHD pharmacotherapies are not effective in patients with this comorbidity and cognitive behavioral therapy (CBT) has not been tested in this population. This RCT aimed to compare the efficacy of Integrated CBT (CBT/Integrated) directed at adult ADHD and SUD with CBT directed at SUD only (CBT/SUD) in patients with SUD and ADHD (SUD + ADHD). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.023DOI Listing
February 2019

Flavored cigar smoking among African American young adult dual users: An ecological momentary assessment.

Drug Alcohol Depend 2019 Mar 31;196:79-85. Epub 2019 Jan 31.

University of Connecticut, School of Medicine, CT, USA. Electronic address:

Background: Flavored cigar sales have increased in recent years in the U.S. African American young adults (AAYAs) have high prevalence of smoking flavored cigars and dual use with cigarettes, but the predictors of use are unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377319PMC

Synthetic cathinone MDPV enhances reward function through purinergic P2X7 receptor-dependent pathway and increases P2X7 gene expression in nucleus accumbens.

Drug Alcohol Depend 2019 Jan 31;197:22-27. Epub 2019 Jan 31.

Center for Substance Abuse Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA; Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. Electronic address:

Background And Purpose: Purinergic P2X7 receptors are present on neurons, astrocytes and microglia and activated by extracellular ATP. Since P2X7 receptor activation releases endogenous substrates (e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.022DOI Listing
January 2019

Smoking related outcomes before and after implementation of tobacco-free grounds in residential substance use disorder treatment programs.

Drug Alcohol Depend 2019 Feb 5;197:8-14. Epub 2019 Feb 5.

Philip R. Lee Institute for Health Policy Studies, University of California San Francisco, CA, USA; Department of Psychiatry and Weill Institute for Neuroscience, University of California San Francisco, CA, USA.

Background: This study examined the impact of a tobacco-free grounds (TFG) policy and the California $2.00/pack tobacco tax increase on tobacco use among individuals in residential substance use disorder (SUD) treatment.

Methods: We conducted three cross-sectional surveys of clients enrolled in three residential SUD treatment programs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2019.01.001DOI Listing
February 2019
1 Read

Associations between drug use patterns and viral load suppression among HIV-positive individuals who use support services in New York City.

Drug Alcohol Depend 2019 Jan 15;197:15-21. Epub 2019 Jan 15.

New York City Department of Health and Mental Hygiene, Bureau of HIV/AIDS Prevention and Control, 42-09 28th Street, Queens, NY, 11101-4132, USA.

Background: Drug use (DU) represents a significant barrier to maintaining physical health among people living with HIV (PLWH). Few studies, however, have examined the relationship between DU over time and HIV treatment outcomes. Such studies are needed because an individual's risk of poor health outcomes may vary with their DU behaviors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.015DOI Listing
January 2019

Very-low-nicotine-content cigarettes and dependence among non-daily smokers.

Drug Alcohol Depend 2019 Jan 31;197:1-7. Epub 2019 Jan 31.

University of Pittsburgh, Department of Biostatistics, Pittsburgh, PA, USA.

Background: The US Food and Drug Administration is considering reductions in the nicotine content of cigarettes to reduce smoking and tobacco dependence. A randomized study showed that even non-daily, intermittent smokers (ITS) reduced their cigarette consumption when switched to very-low-nicotine-content cigarettes (VLNCCs). This paper assesses whether switching ITS to VLNCCs results in decreased dependence and whether subsequent cigarette consumption is mediated by decreased dependence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.021DOI Listing
January 2019

Attitudes, beliefs, and knowledge of substance use amongst youth in the Eastern Mediterranean region: A systematic review.

Drug Alcohol Depend 2019 Mar 22;196:71-78. Epub 2019 Jan 22.

Department of Psychiatry, American University of Beirut, Beirut, Lebanon. Electronic address:

Background: Substance use has a tremendous impact on the burden of disease. This is particularly true in the Eastern Mediterranean region (EMR), where many countries serve as suppliers of drugs. As risk perception and frequency of use are inversely correlated, targeting perception during adolescence becomes essential for prevention. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716193002
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.019DOI Listing
March 2019
7 Reads

Trends in marijuana use among pregnant women with and without nausea and vomiting in pregnancy, 2009-2016.

Drug Alcohol Depend 2019 Mar 18;196:66-70. Epub 2019 Jan 18.

Regional Offices, Kaiser Permanente Northern California, 1950 Franklin, Oakland CA 94612, USA.

Background: Cross-sectional studies indicate an elevated prevalence of prenatal marijuana use in women with nausea and vomiting in pregnancy (NVP). However, it is unknown whether differences in marijuana use by NVP status have persisted over time as marijuana becomes more acceptable and accessible and prenatal use increases overall. We compared trends in prenatal marijuana use by NVP status in the first trimester of pregnancy using data from Kaiser Permanente Northern California's (KPNC) large healthcare system. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716193000
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.009DOI Listing
March 2019
4 Reads

"Flakka" use among high school seniors in the United States.

Drug Alcohol Depend 2019 Mar 29;196:86-90. Epub 2019 Jan 29.

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States; Center for Research on Society and Health,Universidad Mayor, Santiago, Chile.

Background: Use of synthetic cathinones, commonly referred to as "bath salts", has been associated with tens of thousands of emergency department visits in the US; however, few national studies have estimated prevalence of use and we know very little about use among adolescents. In this study we estimate prevalence and correlates of use of "Flakka" (alpha-PVP), a highly-potent "bath salt" associated with at least 80 deaths in the US.

Methods: We analyzed data from the 2016/2017 Monitoring the Future study, which surveyed a nationally representative sample of high school seniors in the US (n = 3786). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377311PMC

Prescribing diamorphine in the United States: Insights from a nationally representative survey.

Drug Alcohol Depend 2019 Mar 4;196:62-65. Epub 2019 Jan 4.

Carnegie Mellon University Heinz College, 5000 Forbes Ave., Pittsburgh PA 1521, United States.

Background: Some countries allow physicians to prescribe pharmaceutical-grade diamorphine to dependent users who have previously undergone treatment but are still using street-sourced heroin; this is not allowed in the US. This study provides the first nationally representative US data concerning public support for prescribing diamorphine to dependent users. We also test the hypothesis that calling it "diamorphine" instead of "heroin" increases support for this approach. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716193000
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.007DOI Listing
March 2019
3 Reads

Prevalence of binge drinking and relationships between masculine role discrepancy and binge drinking via discrepancy stress among Chinese men.

Drug Alcohol Depend 2019 Mar 15;196:57-61. Epub 2019 Jan 15.

Centre for Health Behaviours Research, J.C. School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

Background: Binge drinking is prevalent among male populations. Few studies have investigated masculine role discrepancy (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.013DOI Listing
March 2019
3 Reads

Pregnant women with opioid use disorder and their infants in three state Medicaid programs in 2013-2016.

Drug Alcohol Depend 2019 Feb 3;195:156-163. Epub 2019 Jan 3.

Research and Rapid-cycle Evaluation Group, Center for Medicare and Medicaid Innovation, Centers for Medicare and Medicaid Services, Mail Stop: WB-19-72, 7500 Security Boulevard, Baltimore, MD, 21244, USA.

Background: Maternal opioid use disorder (OUD) has serious consequences for maternal and infant health. Analysis of Medicaid enrollee data is critical, since Medicaid bears a disproportionate share of costs.

Methods: This study analyzes linked maternal and infant Medicaid claims data and infant birth records in three states in the year before and after a delivery in 2014-2015 (2013-2016) examining health, health care use, treatment, and neonatal outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.005DOI Listing
February 2019
3 Reads

Making a bridge between general hospital and specialised community-based treatment for alcohol use disorder-A pragmatic randomised controlled trial.

Drug Alcohol Depend 2019 Mar 17;196:51-56. Epub 2019 Jan 17.

Unit of Clinical Alcohol Research, Clinical Institute, University of Southern Denmark, J.B. Winsløws Vej 20, Indgang 220B, 5000 Odense, Denmark; Psychiatric Department, University Function, Region of Southern Denmark, Denmark.

Aim: To investigate if more patients in the intervention group attended specialized alcohol treatment compared with a treatment-as-usual group (TAU).

Methods: Pragmatic randomized controlled trial where consecutive patients, admitted to somatic hospitals, filled out a lifestyle questionnaire with the Alcohol Use Disorder Identification Test (AUDIT) embedded. Patients scoring 8+ on AUDIT were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.017DOI Listing
March 2019
2 Reads

Changing risk and presentation of overdose associated with consumption of street drugs at a supervised injection site in Vancouver, Canada.

Drug Alcohol Depend 2019 Mar 15;196:46-50. Epub 2019 Jan 15.

Vancouver Coastal Health, Vancouver, British Columbia, Canada; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

Background: British Columbia is experiencing a public health emergency due to overdoses resulting from consumption of street drugs contaminated with fentanyl. While the risk of overdoses appears to be increasing, the overdose rate and severity of overdose presentations have yet to be quantified.

Methods: Insite is a supervised injection site in Vancouver. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.016DOI Listing
March 2019
1 Read

Social integration and alcohol consumption among older people: A four-year follow-up of a Swedish national sample.

Drug Alcohol Depend 2019 Mar 15;196:40-45. Epub 2019 Jan 15.

Aging Research Center, Karolinska Institutet/Stockholm University, Tomtebodavägen 18A, 171 65, Solna, Sweden. Electronic address:

Background: Today's older people drink more alcohol than earlier cohorts of older people. Social integration has been identified as an important factor for older people's drinking, but the association is complex. This study investigates both high and low levels of social integration and their associations with longitudinal patterns of alcohol consumption among older women and men. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.011DOI Listing
March 2019
2 Reads

Sex-specific association of depressive disorder and transient emotional states with alcohol consumption in male and female alcoholics.

Drug Alcohol Depend 2019 Mar 11;196:31-39. Epub 2019 Jan 11.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

Background: We assessed the impact of comorbid depression and anxiety disorders as well as positive and negative emotional states on alcohol consumption in alcohol dependent men and women.

Methods: Per day alcohol consumption during 90 days before enrolment was assessed by the Time Line Follow Back (TLFB) in 287 men and 156 women meeting DSM-IV-TR criteria for alcohol dependence. Propensity to drink in negative/positive emotional states was assessed using the Inventory of Drug Taking Situations (IDTS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.010DOI Listing
March 2019
2 Reads

Cluster randomized stepped-wedge trial of a multi-level HIV prevention intervention to decrease amphetamine-type stimulants and sexual risk in Cambodian female entertainment and sex workers.

Drug Alcohol Depend 2019 Mar 11;196:21-30. Epub 2019 Jan 11.

Ministry of Health, Department of Mental Health and Substance Abuse, Phnom Penh, Cambodia; Kirby Institute for Infection and Immunity, UNSW Sydney, Sydney, Australia. Electronic address:

Background: HIV prevention for female entertainment and sex workers (FESW) may be optimized by addressing individual and structural risks. We examined the impact of a sequentially delivered intervention to decrease sexual risk, amphetamine-type stimulant (ATS) use, and improve economic well-being in Cambodian FESW.

Methods: A cluster randomized stepped-wedge trial was conducted in 10 Cambodian provinces to test multi-level intervention in high risk FESW. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.029DOI Listing
March 2019
3 Reads

Adverse symptoms users attribute to e-cigarettes: Results from a national survey of US adults.

Drug Alcohol Depend 2019 Mar 11;196:9-13. Epub 2019 Jan 11.

Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157, USA.

Background: Little is known about the prevalence of adverse symptoms electronic cigarette (e-cigarette) users report experiencing.

Methods: Between August 2016 and May 2017, we conducted a nationally representative cross-sectional telephone survey of 4964 US adults age 18 and over. Respondents who reported ever trying e-cigarettes were asked whether they ever experienced six symptoms they thought were caused by e-cigarette use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377331PMC
March 2019
1 Read

Beliefs and attitudes regarding prenatal marijuana use: Perspectives of pregnant women who report use.

Drug Alcohol Depend 2019 Mar 11;196:14-20. Epub 2019 Jan 11.

Department of Medicine, University of Pittsburgh School of Medicine, 1218 Scaife Hall, Pittsburgh, PA, 15260, USA; Center for Research in Healthcare, University of Pittsburgh, 4200 Fifth Avenue, Pittsburgh, PA, 15260, USA; Section of Palliative Care and Medical Ethics, Institute to Enhance Palliative Care, 230 McKee Place, Pittsburgh, PA, 15213, USA.

Objective: With the increasingly permissive legal and social environments regarding marijuana, it is important to understand prenatal marijuana use from the perspective of women who use marijuana. Our objective was to qualitatively describe the marijuana use experiences, beliefs, and attitudes of women who used marijuana during pregnancy.

Methods: We conducted semi-structured interviews with pregnant women who had either reported current marijuana use or had urine testing positive for marijuana. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.028DOI Listing
March 2019
2 Reads
3.423 Impact Factor

Fentanyl and fentanyl-analog involvement in drug-related deaths.

Drug Alcohol Depend 2019 Mar 9;196:1-8. Epub 2019 Jan 9.

West Virginia Office of the Chief Medical Examiner, West Virginia Department of Health and Human Resources, 619 Virginia Street West, Charleston, WV 25302, United States. Electronic address:

Background: To describe and analyze the involvement of fentanyl and fentanyl analogs (FAs) in drug-related deaths in West Virginia (WV), United States.

Methods: Retrospective analyses of all WV drug-related deaths from 2005 to 2017 were performed, including comparisons of demographic and toxicological characteristics among total deaths, deaths in which fentanyl/FAs were present, deaths in which they were absent, heroin-related deaths, and prescription opioid-related deaths.

Results: Most of the 8813 drug-related deaths were overdoses, with about 11% resulting from transportation/other injuries in which drugs were contributors. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716193000
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.004DOI Listing
March 2019
3 Reads

PrEP awareness, eligibility, and interest among people who inject drugs in Baltimore, Maryland.

Drug Alcohol Depend 2019 Feb 22;195:148-155. Epub 2018 Oct 22.

Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA. Electronic address:

Background: Limited research has examined pre-exposure prophylaxis (PrEP) interest among people who inject drugs (PWID). To date, few studies have examined the relationship between PrEP eligibility and PrEP interest among PWID.

Methods: Data were from an anonymous, cross-sectional survey of Baltimore Syringe Services Program (SSP) clients and non-client peers, restricted to HIV-uninfected participants (N = 265). Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183064
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.08.014DOI Listing
February 2019
4 Reads

Driving under the influence of cannabis among medical cannabis patients with chronic pain.

Drug Alcohol Depend 2019 Feb 9;195:193-197. Epub 2019 Jan 9.

University of Michigan Addiction Center, Department of Psychiatry, University of Michigan School of Medicine, 4250 Plymouth Road, Ann Arbor, MI, 48109, United States; VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105, United States.

Background: Driving under the influence of cannabis (DUIC) is a public health concern among those using medical cannabis. Understanding behaviors contributing to DUIC can inform prevention efforts. We evaluated three past 6-month DUIC behaviors among medical cannabis users with chronic pain. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183082
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359955PMC
February 2019
4 Reads

Cardiovascular effects of 3,4-methylenedioxypyrovalerone (MDPV) in male and female Sprague-Dawley rats.

Drug Alcohol Depend 2019 Feb 4;195:140-147. Epub 2019 Jan 4.

Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. Electronic address:

Background: 3,4-methylenedioxypyrovalerone (MDPV) toxicity includes intense neurological and cardiovascular events. We examined MDPV-induced cardiovascular, temperature, and locomotor effects following escalating and repeated MDPV administration in adult male and female Sprague-Dawley rats and compared these effects to cocaine in male rats.

Methods: Telemetry devices were surgically implanted to allow continuous measurement of cardiovascular, temperature, and locomotor activity over a 22 h period after dosing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.006DOI Listing
February 2019
2 Reads

The role of emotion dysregulation in the relation of childhood trauma to heroin craving in individuals with heroin dependence.

Drug Alcohol Depend 2019 Feb 4;195:132-139. Epub 2019 Jan 4.

Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Objectives: Difficulties in emotion regulation (DER) may be important in heroin craving in individuals with heroin dependence who have experienced childhood trauma (CT). However, no research has been performed on DER in the context of heroin dependence. The aim of this study was to evaluate direct and indirect relations of CT to the subscales of heroin craving (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.008DOI Listing
February 2019
1 Read

Prenatal cocaine exposure: Direct and indirect associations with 21-year-old offspring substance use and behavior problems.

Drug Alcohol Depend 2019 Feb 24;195:121-131. Epub 2018 Nov 24.

University of Pittsburgh School of Medicine, Department of Psychiatry, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.

Background: Prenatal cocaine exposure (PCE) has been linked to child/adolescent behavior problems and substance use in several longitudinal cohort studies. It is unclear whether these effects extend into adulthood and influence young adult behavior problems and substance use and, if so, whether they are mediated by childhood and adolescent experiences.

Methods: These data are from an ongoing longitudinal study of individuals born to women who were recruited early in pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.10.033DOI Listing
February 2019
1 Read

Hepatitis C continuum of care and utilization of healthcare and harm reduction services among persons who inject drugs in Seattle.

Drug Alcohol Depend 2019 Feb 26;195:114-120. Epub 2018 Dec 26.

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Background: To describe the "continuum of care" for hepatitis C virus (HCV) and related health service utilization among persons who inject drugs (PWID) in the Seattle metropolitan area.

Methods: The study analyzed data from the 2015 National HIV Behavioral Surveillance system focused on PWID, which included local questions on HCV treatment and testing. We calculated respondent driven sampling (RDS)-adjusted percentages of participants who had completed each step of the care continuum and compared healthcare harm reduction services among participants who were HCV + vs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.026DOI Listing
February 2019
1 Read

Toxicological oral fluid results among Spanish drivers testing positive on on-site drug controls from 2013 to 2015.

Drug Alcohol Depend 2019 Feb 29;195:106-113. Epub 2018 Dec 29.

Servicio de Toxicología, Instituto de Ciencias Forenses, Universidad de Santiago de Compostela, C/San Francisco, s/n, Santiago de Compostela, Spain. Electronic address:

Background: Driving under the influence of drugs (DUID) increases the risk of serious injury or death in traffic accidents. The aim of this study was to provide information about DUID in Spanish drivers.

Methods: 10,064 oral fluid samples were collected from Spanish drivers that tested positive on the roadside using the Dräger DrugTest 5000 (DDT5000) between 2013 and 2015. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183084
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.003DOI Listing
February 2019
2 Reads

Smartphone application for unhealthy alcohol use: Pilot randomized controlled trial in the general population.

Drug Alcohol Depend 2019 Feb 22;195:101-105. Epub 2018 Dec 22.

Centre for Addiction and Mental Health, Toronto, Canada. Electronic address:

Background: There is limited evidence of the efficacy of smartphone applications to reduce unhealthy alcohol use. We tested the efficacy of providing access to a smartphone-based brief intervention for unhealthy alcohol use.

Methods: We conducted a two parallel-group randomized controlled trial with follow-up at 6 months, among 977 individuals with an Alcohol Use Disorder Identification Test ≥8 and drinking 15 or more drinks/week. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183050
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.002DOI Listing
February 2019
5 Reads

Geographic patterns of prescription opioids and opioid overdose deaths in New York State, 2013-2015.

Drug Alcohol Depend 2019 Feb 30;195:94-100. Epub 2018 Dec 30.

Program in Public Health, Department of Family, Population, and Preventive Medicine, Stony Brook University, Stony Brook, NY 11794, USA.

Objectives: To examine the relationship between prescription opioid rates and prescription opioid overdose deaths using spatial cluster and regression analyses.

Methods: Publicly available county-level data were obtained from the New York State Health Department and the Centers for Disease Control and Prevention, 2013-2015. Kulldorff's spatial scan statistic was used to investigate spatial clustering of New York State opioid prescription overdose death rates, as well as opioid prescription rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.027DOI Listing
February 2019
1 Read

Being old fashioned in a modern world: Gender role attitudes moderate the relation between role conflicts and alcohol use of parents.

Drug Alcohol Depend 2019 Feb 21;195:90-93. Epub 2018 Dec 21.

Centre for Alcohol Policy Research (CAPR), School of Psychology and Public Health, La Trobe University, Melbourne, Australia; Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands.

Background: Balancing contradictory demands of different social roles such as work and family can lead to role conflicts. However, whether such conflicts lead to detrimental alcohol use may depend on the individual's gender role attitudes (GRA). For example, considering family care taking as a female task, and breadwinning as a male task. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.025DOI Listing
February 2019
1 Read

Assessing tobacco use in an African population: Serum and urine cotinine cut-offs from South Africa.

Drug Alcohol Depend 2019 Feb 21;195:82-89. Epub 2018 Dec 21.

Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa; MRC Research Unit for Hypertension and Cardiovascular Disease, North-West University, South Africa. Electronic address:

Background: Cotinine, a nicotine metabolite, is used to measure tobacco use and exposure, but recommended cut-offs to differentiate tobacco users from those exposed through the environment range from 3 to 58 ng/ml in serum, and 2.5 to 550 ng/ml in urine. Cut-offs may differ by ethnicity, sex and age. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.022DOI Listing
February 2019
1 Read
3.423 Impact Factor

Explaining continuity in substance use: The role of criminal justice system involvement over the life course of an urban African American prospective cohort.

Drug Alcohol Depend 2019 Feb 8;195:74-81. Epub 2018 Dec 8.

Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA. Electronic address:

Background: African Americans are disproportionately burdened by substance use consequences and criminal justice system involvement, yet their interrelationship over the life course is not well understood. This study aimed to assess how substance use, crime, and justice system involvement may influence one another from adolescence to midlife.

Methods: Data come from a community cohort of urban African Americans first assessed in childhood and followed up into midlife (n = 1242, 606 males, 636 females). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.09.033DOI Listing
February 2019
1 Read

Urban-rural variation in the socioeconomic determinants of opioid overdose.

Drug Alcohol Depend 2019 Feb 21;195:66-73. Epub 2018 Dec 21.

Violence Prevention Research Program, Department of Emergency Medicine, University of California Davis School of Medicine, 2315 Stockton Blvd., Sacramento, CA 95817, USA; Division of Epidemiology, Department of Population Health, New York University School of Medicine, 650 First Ave., New York, NY 10016, USA.

Background: Prescription opioid overdose (POD) and heroin overdose (HOD) rates have quadrupled since 1999. Community-level socioeconomic characteristics are associated with opioid overdoses, but whether this varies by urbanicity is unknown.

Methods: In this serial cross-sectional study of zip codes in 17 states, 2002-2014 (n = 145,241 space-time units), we used hierarchical Bayesian Poisson space-time models to analyze the association between zip code-level socioeconomic features (poverty, unemployment, educational attainment, and income) and counts of POD or HOD hospital discharges. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375680PMC
February 2019
1 Read
3.423 Impact Factor

Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity.

Drug Alcohol Depend 2019 Feb 21;195:59-65. Epub 2018 Dec 21.

McLean Imaging Center, McLean Hospital, 115 Mill St., Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA, 02215, USA.

Background: Women experience greater difficulty quitting smoking than men, which may be explained by sex differences in brain circuitry underlying cognitive control. Prior work has linked reduced interhemispheric executive control network (ECN) coupling with poor executive function, shorter time to relapse, and greater substance use. Lower structural connectivity between a key ECN hub, the dorsolateral prefrontal cortex (DLPFC), and the dorsal striatum (DS) also contributes to less efficient cognitive control recruitment, and reduced intrahemispheric connectivity between these regions has been associated with smoking relapse. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.023DOI Listing
February 2019
1 Read

Screening for adult attention-deficit/hyperactivity disorder in alcohol dependent patients: Underreporting of ADHD symptoms in self-report scales.

Drug Alcohol Depend 2019 Feb 10;195:52-58. Epub 2018 Dec 10.

MEDIAN Klinik Wilhelmsheim, Oppenweiler, Germany.

Background: Attention-deficit/hyperactivity disorder (ADHD) is a common comorbid disorder that is frequently overlooked in adults with alcohol use disorder (AUD). Moreover, identifying ADHD in AUD patients is time-consuming and difficult. The aim of this study was to assess the clinical utility of two self-report screening instruments for adult ADHD in AUD patients. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183083
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.020DOI Listing
February 2019
4 Reads

A randomized controlled trial of a manual-only treatment for reduction and cessation of problematic caffeine use.

Drug Alcohol Depend 2019 Feb 24;195:45-51. Epub 2018 Nov 24.

Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD, 21224, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD, 21224, USA.

Background: Caffeine Use Disorder was added to DSM-5 as a diagnosis for further research, but few studies have been conducted to identify effective treatments. This randomized, controlled clinical trial examined the efficacy of a manual-only treatment program for caffeine cessation and reduction among individuals seeking treatment for problematic caffeine use.

Methods: Individuals meeting at least two proposed DSM-5 diagnostic criteria for Caffeine Use Disorder were randomly assigned to receive either immediate treatment or treatment delayed by 7 weeks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.10.034DOI Listing
February 2019
1 Read

Secondary distribution of injecting equipment obtained from needle and syringe programmes by people injecting image and performance enhancing drugs: England and Wales, 2012-15.

Drug Alcohol Depend 2019 Feb 14;195:40-44. Epub 2018 Dec 14.

National Infection Service, Public Health England, London, UK.

Background: People who inject image and performance enhancing drugs (IPEDs) are often the largest group using needle and syringe programmes (NSPs) in the UK. NSP providers report these clients repeatedly collecting large amounts of equipment for others. The extent of secondary distribution of injecting equipment is unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.021DOI Listing
February 2019
2 Reads

Higher average potency across the United States is associated with progression to first cannabis use disorder symptom.

Drug Alcohol Depend 2019 Feb 17;195:186-192. Epub 2018 Dec 17.

Department of Psychiatry, University of Michigan Addiction Center, 4250 Plymouth Road, Ann Arbor, MI 48109 USA. Electronic address:

Objective: To determine if higher potency cannabis is associated with earlier progression to regular cannabis use, daily cannabis use, and cannabis use disorder symptom onset.

Methods: Data sources were the Michigan Longitudinal Study, an ongoing prospective, high-risk family study investigating the course and predictors for substance use disorders among youth beginning prior to school entry and time-parallel national average trends in delta-9-tetrahydrocannabinol (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376862PMC
February 2019
2 Reads

An ecological momentary assessment study examining posttraumatic stress disorder symptoms, prenatal bonding, and substance use among pregnant women.

Drug Alcohol Depend 2019 Feb 8;195:33-39. Epub 2018 Dec 8.

Departments of Family and Community Medicine, Obstetrics and Gynecology, University of New Mexico School of Medicine, Albuquerque, NM 87131 USA.

Background: Substance use disorder (SUD) during pregnancy requires efficacious interventions based on understanding the ebb and flow of risk and protective factors for substance use across time. To assess how these fluctuations are associated temporally with substance use, we used ecological momentary assessment (EMA) to evaluate substance use risk (posttraumatic stress disorder [PTSD] symptoms) and protective (prenatal fetal bonding) factors and their associations with prenatal substance use recorded in real time.

Methods: Pregnant women in SUD treatment (N = 33) with prior trauma exposure received smartphones with an EMA application that queried them thrice daily for 28 days about PTSD symptoms, prenatal bonding, and substance use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359965PMC
February 2019
8 Reads

Withdrawal symptoms predict prescription opioid dependence in chronic pain patients.

Drug Alcohol Depend 2019 Feb 3;195:27-32. Epub 2018 Dec 3.

University General Hospital of Elche, Camino de la Almazara, 11, 03203, Elche, Spain. Electronic address:

Background: The last version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes substantial changes for prescription opioid-use disorder (POUD). After its removal as a criterion, the goal of this study was to estimate the prevalence of withdrawal symptoms in long-term users of prescription opioids and its association with the new DSM-5 POUD classification.

Methods: Data were collected from 215 long-term consumers of opioid medication who were chronic non-cancer pain patients. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03768716183082
Publisher Site
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.013DOI Listing
February 2019
10 Reads

Addressing the nexus of risk: Biobehavioral outcomes from a cluster randomized trial of the Women's Health CoOp Plus in Pretoria, South Africa.

Drug Alcohol Depend 2019 Feb 3;195:16-26. Epub 2018 Dec 3.

Research Computing Division, RTI International, 3040 E. Cornwallis Road, Research Triangle Park, NC, USA.

Background: HIV prevalence has increased among South African women who use alcohol and other drugs (AOD). However, HIV prevention and treatment efforts have not focused on this population. This study presents the efficacy of the Women's Health CoOp Plus (WHC+) in a cluster-randomized trial to reduce AOD use, gender-based violence, and sexual risk and to increase linkage to HIV care among women who use AODs, compared with HIV counseling and testing alone. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.10.036DOI Listing
February 2019
1 Read

Smoking cessation in the context of recovery from drug and alcohol problems: Prevalence, predictors, and cohort effects in a national U.S. sample.

Drug Alcohol Depend 2019 Feb 8;195:6-12. Epub 2018 Dec 8.

Recovery Research Institute, Massachusetts General Hospital and Harvard Medical School, 151 Merrimac Street, Boston, MA, 02114, USA.

Background: Tobacco and alcohol and other drug (AOD) use remain prominent risk factors for morbidity, mortality, and health care utilization. Moreover, these often cluster together within persons, exponentiating health risks. Little is known regarding if and when people resolving AOD problems stop smoking, who stops, and whether recent general population trends toward smoking cessation are evident also among persons more recently entering recovery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359967PMC
February 2019
2 Reads

Use of marijuana exclusively for medical purposes.

Drug Alcohol Depend 2019 Feb 4;195:13-15. Epub 2018 Dec 4.

Department of Psychiatry, Columbia University, 1051 Riverside Drive, New York, NY 10032, United States; New York State Psychiatric Institute, New York, NY, United States.

Objectives: To characterize the socio-demographic characteristics, medical conditions, and psychiatric comorbidities of users of marijuana for medical and non-medical purposes.

Methods: Data were from the National Epidemiological Survey on Alcohol and Related Conditions III, a US nationally representative in-person interview of 36,309 adults age ≥18 years in 2012-2013.

Results: In relation to non-medical only users (n = 3339), combined (n = 362) and medical only (n = 82) users had higher prevalence of every medical condition examined. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.009DOI Listing
February 2019
5 Reads
3.423 Impact Factor

Shifting characteristics of nonmedical prescription tranquilizer users in the United States, 2005-2014.

Drug Alcohol Depend 2019 Feb 8;195:1-5. Epub 2018 Dec 8.

Columbia University, Department of Epidemiology, Mailman School of Public Health, New York, NY, USA.

Background: Benzodiazepine overdose rates have increased in the US, largely from concomitant use of other drugs such as opioids. Studies are needed to examine trends in prescription tranquilizer (e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359959PMC
February 2019
1 Read

Stakeholder perspectives on implementing fentanyl drug checking: Results from a multi-site study.

Drug Alcohol Depend 2019 Jan 13;194:527-532. Epub 2018 Nov 13.

Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Hampton House 163, Baltimore, MD, USA.

Background: The opioid epidemic is one of the greatest public health crises of our times, driven increasingly by synthetic opioids such as fentanyl in the heroin supply. The implementation of drug checking in community settings has the potential to reduce the burden of fatal overdose, provide harm reduction education around safer drug consumption, and increase health access among people who use drugs (PWUD). To inform program development, we explored stakeholder opinions on drug checking technologies and implementation considerations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.10.017DOI Listing
January 2019
10 Reads

Erratum to "When DAWN went dark: Can the Nationwide Emergency Department Sample (NEDS) fill the surveillance gap left by the discontinued Drug Abuse Warning Network (DAWN)?" [Drug Alcohol Depend. (2018) 201-207].

Drug Alcohol Depend 2019 Jan 11;194:526. Epub 2018 Dec 11.

Office of National Drug Control Policy, Executive Office of the President, Washington DC, 20503, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.12.001DOI Listing
January 2019
1 Read

Examining the link between reward and response inhibition in individuals with substance abuse tendencies.

Drug Alcohol Depend 2019 Jan 3;194:518-525. Epub 2018 Dec 3.

Department of Psychological and Brain Sciences, Texas A and M University, 400 Bizzell St., College Station, TX, 77843, USA.

Background: Substance use problems are often characterized by dysregulation in reward sensitivity and inhibitory control. In line with this representation, the goal of this investigation was to determine how substance abuse tendencies among university students affect incentivized response inhibition. Additionally, this study examined whether striatal dopamine moderates the impact of substance use on response inhibition performance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2018.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340392PMC
January 2019
1 Read