7,460 results match your criteria Drug and Alcohol Dependence[Journal]


Veterans with PTSD and comorbid substance use disorders: Does single versus poly-substance use disorder affect treatment outcomes?

Drug Alcohol Depend 2019 Apr 9;199:70-75. Epub 2019 Apr 9.

Department of Behavioral Sciences and Psychiatry, Division of Addiction Sciences, Medical University of South Carolina, 5 Charleston Center Dr., Suite 151, Charleston, SC, 29401 USA; Ralph H. Johnson VA Medical Center, 109 Bee St., Charleston, SC, 29401 USA.

Introduction: Substance use disorders (SUD) frequently co-occur with posttraumatic stress disorder (PTSD). Little is known, however, about how individuals with a single SUD diagnosis (relating to only one substance) compare to individuals with poly-SUD diagnoses (relating to more than one substance) on substance use and PTSD treatment outcomes. To address this gap in the literature, we utilized data from a larger study investigating a 12-week integrated, exposure-based treatment (i. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.04.001DOI Listing

Corrigendum to "The moderating effect of perceived social support on the relation between heaviness of smoking and quit attempts among adult homeless smokers" [Drug and Alcohol Depend. 190 (2018) 128-132].

Drug Alcohol Depend 2019 Apr 19;199:69. Epub 2019 Apr 19.

The University of Oklahoma Health Sciences Center, Oklahoma Tobacco Research Center, 655 Research Parkway, Suite 400, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.04.003DOI Listing

Corrigendum to "Concurrent nicotine and tobacco product use among homeless smokers and associations with cigarette dependence and other factors related to quitting" [Drug Alcohol Depend. 185 (2018) 133-140].

Drug Alcohol Depend 2019 Apr 19;199:68. Epub 2019 Apr 19.

Oklahoma Tobacco Research Center, The University of Oklahoma Health Sciences Center, 655 Research Parkway, Suite 400, Oklahoma City, OK, 73104, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.04.002DOI Listing
April 2019
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Parental views on state cannabis laws and marijuana use for their medically vulnerable children.

Drug Alcohol Depend 2019 Feb 14;199:59-67. Epub 2019 Feb 14.

Division of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, MA, United States; Department of Pediatrics, Harvard Medical School, Boston, MA, United States.

Background: Given a rapidly changing policy landscape, we sought to characterize the effects of state marijuana laws on parents' views of marijuana use by their teenage children.

Methods: Data are from 595 respondents to a nationally administered, web-based survey of parents of adolescents (ages 13-18 years) with any of three chronic conditions (type 1 diabetes, rheumatic disease, attention-deficit/hyperactivity disorder). Multivariate ordinal logistic regression was used to model the effects of parents' reports of state cannabis laws on their views toward marijuana use by their child. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716183050
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http://dx.doi.org/10.1016/j.drugalcdep.2018.12.027DOI Listing
February 2019
2 Reads

Retraction notice to Confirmed Marijuana Use and Lymphocyte Count in Black People Living with HIV [DAD 180 (2017) 22 - 25].

Drug Alcohol Depend 2019 May;198:199

University of Florida Center for AIDS/HIV Research, Service, and Education University of Florida, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.03.001DOI Listing
May 2019
1 Read

Locomotor activity and discriminative stimulus effects of five novel synthetic cathinone analogs in mice and rats.

Drug Alcohol Depend 2019 Apr 6;199:50-58. Epub 2019 Apr 6.

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.

Background: The development of novel synthetic psychoactive substances continues to accelerate. There are little or no data on the pharmacological mechanisms, behavioral effects, or abuse liability of many of the newer compounds, despite increasing reports of severe adverse effects in recreational users.

Methods: The current study investigated the discriminative stimulus and locomotor stimulant effects of a group of synthetic cathinone analogs: N-ethylpentylone, dimethylone, dibutylone, clephedrone, 3',4'-tetramethylene-α-pyrrolidinovalerophenone (TH-PVP). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193009
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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.016DOI Listing
April 2019
4 Reads

Resiliency factors that protect against post-deployment drug use among male US Army Reserve and National Guard soldiers.

Drug Alcohol Depend 2019 Apr 6;199:42-49. Epub 2019 Apr 6.

Department of Community Health and Health Behavior, University at Buffalo, The State University of New York, Buffalo, NY, USA.

Background: Service members who have been deployed are at risk for substance use, especially Reserve/Guard troops. However, it is unclear what modifiable factors protect against substance use in this at-risk population. Our objective was to examine the effects of pre-, peri-, and post-deployment resiliency factors on post-deployment drug use. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.017DOI Listing
April 2019
8 Reads

Prospective associations between insomnia symptoms and alcohol use problems among former and current military service personnel.

Drug Alcohol Depend 2019 Apr 6;199:35-41. Epub 2019 Apr 6.

College of Nursing, Medical University of South Carolina, 99 Jonathan Lucas St, Charleston, SC, 29425, USA.

Background: Despite evidence that insomnia symptoms exacerbate alcohol use disorder symptoms, there is a dearth of prospective research testing bidirectional associations between these variables. Furthermore, no studies have prospectively examined these associations among military personnel, a vulnerable population for sleep- and alcohol-related problems. Thus, the current study examined whether insomnia symptoms prospectively predicted increased alcohol use disorder symptoms among a sample of military service members and veterans over a 6-month follow-up period, as well as whether alcohol use disorder symptoms led to increases in insomnia. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.018DOI Listing

Leisure activities and alcohol consumption among adolescents from Peru and El Salvador.

Drug Alcohol Depend 2019 Apr 6;199:27-34. Epub 2019 Apr 6.

Institute for Culture and Society, Universidad de Navarra, Campus Universitario, 31080, Pamplona, Spain; Preventive Medicine and Public Health, School of Medicine, Universidad de Navarra, Campus Universitario, 31080, Pamplona, Spain; IdiSNA, Navarra Institute for Health Research, Calle Irunlarrea 3, 31008, Pamplona, Navarra, Spain.

Introduction: Structured and unstructured leisure are known protective and risk factors, respectively, for alcohol consumption during adolescence. However, little is known about the interaction between the two leisure types and alcohol consumption.

Method: A cross-sectional study was performed among high-school students in El Salvador and Peru. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.03.002DOI Listing
April 2019
3 Reads

Outcome evaluation of a "common factors" approach to develop culturally tailored HIV prevention interventions for people who inject drugs.

Drug Alcohol Depend 2019 Apr 6;199:18-26. Epub 2019 Apr 6.

Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research, Medical College of Wisconsin, 2071 North Summit Ave, Milwaukee, WI, 53202, USA. Electronic address:

Background: Current models of HIV prevention intervention dissemination involve packaging interventions developed in one context and training providers to implement that specific intervention with fidelity. Providers rarely implement these programs with fidelity due to perceived incompatibility, resource constraints, and preference for locally-generated solutions. Moreover, such interventions may not reflect local drug markets and drug use practices that contribute to HIV risk. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.015DOI Listing

Association of electronic cigarette vaping and subsequent smoking relapse among former smokers.

Drug Alcohol Depend 2019 Mar 15;199:10-17. Epub 2019 Mar 15.

Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, United States; Department of Psychology, University of Southern California, Los Angeles, United States; USC Norris Comprehensive Cancer Center, Los Angeles, United States. Electronic address:

Background: Former combustible cigarette smokers who vape e-cigarettes after quitting smoking may experience health benefits if post-quit vaping prevents smoking relapse.

Methods: Former combustible cigarette smokers aged >18 that were recent (quit ≤ 12 months) or long-term (quit > 12 months) quitters at baseline were re-surveyed at 1-year follow-up in the Population Assessment of Tobacco and Health (PATH) U.S. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193007
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.043DOI Listing
March 2019
8 Reads

Effects of mandatory prescription drug monitoring program (PDMP) use laws on prescriber registration and use and on risky prescribing.

Drug Alcohol Depend 2019 Mar 22;199:1-9. Epub 2019 Mar 22.

Institute for Behavioral Health, Brandeis University, Waltham, MA, USA.

Background: Comprehensive mandatory use laws for prescription drug monitoring programs (PDMPs) have been implemented in a number of states to help address the opioid overdose epidemic. These laws may reduce opioid-related overdose deaths by increasing prescribers' use of PDMPs and reducing high-risk prescribing behaviors.

Methods: We used state PDMP data to examine the effect of these mandates on prescriber registration, use of the PDMP, and on prescription-based measures of patient risk in three states-Kentucky, Ohio, and West Virginia-that implemented mandates between 2010 and 2015. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.010DOI Listing

Recreational ART use among individuals living with HIV/AIDS in South Africa: Examining longitudinal ART initiation and viral suppression.

Drug Alcohol Depend 2019 May 22;198:192-198. Epub 2019 Mar 22.

Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Massachusetts General Hospital Center for Global Health, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

Background: South Africa has the highest number of people living with HIV (PLWH) and one of the largest antiretroviral therapy (ART) programs globally. High rates of substance use comorbidity exist, including speculation of recreational ART use (i.e. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.009DOI Listing
May 2019
2 Reads

Klotho levels and ethanol consumption.

Drug Alcohol Depend 2019 May 29;198:190-191. Epub 2019 Mar 29.

Servicio de Medicina Interna, Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Canary Islands 38320, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.013DOI Listing
May 2019
2 Reads

Neural reward response to substance-free activity images in opiate use disorder patients with depressive symptoms.

Drug Alcohol Depend 2019 May 20;198:180-189. Epub 2019 Mar 20.

Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, 235 E. Cameron Ave., Chapel Hill, NC, 27599, USA. Electronic address:

Background: Deficits in the ability to experience reward from natural, substance-free activities and stimuli is a common mechanism contributing to both opiate use disorder and depressive symptoms, and is a target of behavioral-focused treatments for substance use and depression. Although the neural response to monetary, positive affect-eliciting and social images has been investigated, the neural response to images representing substance-free activity engagement remains untested. The current study tested the neural response to anticipation and receipt of substance-free activity engagement images and monetary reward in opiate use disorder patients with elevated depressive symptoms compared to healthy controls. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.047DOI Listing
May 2019
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Screen of drug use: Diagnostic accuracy for opioid use disorder.

Drug Alcohol Depend 2019 May 18;198:176-179. Epub 2019 Mar 18.

VA Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, CA 94304, USA; Department of Psychiatry and Behavioral Sciences, Center for Health Care Evaluation, Stanford University School of Medicine, 152MPD, 795 Willow Road, Menlo Park, CA 94025, USA.

Aims: Opioid related deaths have more than tripled in recent years. Identifying and referring individuals with opioid use disorder (OUD) to treatment is one of the promising approaches to reduce opioid related deaths. However, using urine toxicology to identify opioid misuse is not reliable. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193007
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.044DOI Listing
May 2019
10 Reads

The interaction of sociodemographic risk factors and measures of nicotine dependence in predicting maternal smoking during pregnancy.

Drug Alcohol Depend 2019 May 26;198:168-175. Epub 2019 Mar 26.

Department of Psychiatry, Washington University School of Medicine in St. Louis, 660 S Euclid, CB 8134, St. Louis, MO 63110, USA. Electronic address:

Background: Understanding differences in nicotine dependence assessments' ability to predict smoking cessation is complicated by variation in quit attempt contexts. Pregnancy reduces this variation, as each pregnant smoker receives the same strong cessation incentive. Cigarette smoking during pregnancy (SDP) provides a powerful paradigm for analyzing the interplay between nicotine dependence measures and sociodemographics in predicting cessation failure. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467711PMC
May 2019
2 Reads

Is marijuana use associated with lower inflammation? Results from waves III and IV of the national longitudinal study of adolescent to adult health.

Drug Alcohol Depend 2019 May 27;198:162-167. Epub 2019 Feb 27.

Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, P.O. Box 100165, 1225 Center Drive, Room 3146 Gainesville, FL, 32610-0165, United States. Electronic address:

Background: Some research suggests that marijuana use facilitates an anti-inflammatory response, yet the relationship between marijuana use and inflammation, as measured by C-reactive protein (CRP), remains poorly understood. The present study examined the association between recency of marijuana use and serum C-reactive protein levels in a nationally representative sample of adults.

Methods: Data from Waves III and IV (N = 13,166) of the National Longitudinal Study of Adolescent to Adult Health was utilized. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.021DOI Listing
May 2019
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Trends in and correlates of tranquilizer misuse among adults who misuse opioids in the United States, 2002-2014.

Drug Alcohol Depend 2019 May 16;198:158-161. Epub 2019 Feb 16.

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

Purpose: Almost a third of opioid overdose deaths also involve benzodiazepines, but few representative studies have examined misuse of benzodiazepines and other tranquilizers by adults who misuse opioids. This study estimated the prevalence and frequency of tranquilizer misuse among adults who misuse opioids and examined characteristics associated with tranquilizer misuse.

Methods: A sample of adults who misused opioids in the past year (n = 36,043) were identified in the National Surveys on Drug Use and Health 2002-2014. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.014DOI Listing
May 2019
3 Reads

The polymorphism of dopamine D2 receptor TaqIA gene is associated with brain response to drug cues in male heroin-dependent individuals during methadone maintenance treatment.

Drug Alcohol Depend 2019 May 28;198:150-157. Epub 2019 Feb 28.

Department of Radiology, The Second Affiliated Hospital of Air Force Medical University, Xi'an, 569 Xinsi Road, Baqiao District, China. Electronic address:

Background: Polymorphism of the dopamine D2 receptor TaqIA gene is related to reward response, relapse risks and effect of therapy for drug addiction. Whether the cue-induced craving and brain response was related to dopamine D2 receptor TaqIA gene is unknown.

Methods: Forty-nine male heroin-dependent individuals [31 with A1 allele of the TaqIA (A1+), 18 A2 allele carriers (A1-)] under methadone maintenance treatment and 20 healthy control subjects performed a heroin cue-reactivity task during functional magnetic resonance imaging. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.028DOI Listing
May 2019
4 Reads
3.423 Impact Factor

Longitudinal effects of interoceptive awareness training through mindful awareness in body-oriented therapy (MABT) as an adjunct to women's substance use disorder treatment: A randomized controlled trial.

Drug Alcohol Depend 2019 May 23;198:140-149. Epub 2019 Mar 23.

Department of Psychosocial and Community Health Nursing, University of Washington, Seattle, WA 98195, USA.

Background: Training in interoceptive awareness is a promising behavioral approach for improving substance use disorder (SUD) treatment. This study examined the longitudinal effects of Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to women's SUD treatment. MABT teaches interoceptive awareness skills to promote self-care and emotion regulation. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467707PMC
May 2019
1 Read

Detection of heroin intake in patients in substitution treatment using oral fluid as specimen for drug testing.

Drug Alcohol Depend 2019 May 23;198:136-139. Epub 2019 Mar 23.

MVZ Labor Dessau GmbH, Bauhüttenstraße 6, 06847, Dessau-Roßlau, Germany.

Background: Detection of heroin use is among the major tasks for drug testing and can be best performed by using 6-acetylmorphine as the target analyte. This study was performed to document analytical findings in oral fluid after OF heroin intake.

Methods: The samples were from routine drug testing of patients in substitution treatment. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.011DOI Listing
May 2019
1 Read

Opioid agonist treatment and the process of injection drug use initiation.

Drug Alcohol Depend 2019 Apr 22;197:354-360. Epub 2019 Jan 22.

Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA, USA. Electronic address:

Background: Opioid agonist treatment (OAT) is an effective biomedical intervention to manage opioid use disorder among persons who inject drugs (PWID). Preliminary evidence suggests that OAT may also disrupt the social communicability of injection drug use (IDU) practices by established PWID. We therefore aim to investigate the association between OAT enrollment and initiating others into IDU among PWID in Vancouver, Canada. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2018.12.018DOI Listing
April 2019
1 Read

Treatment cascade for hepatitis C virus in young adult people who inject drugs in San Francisco: Low number treated.

Drug Alcohol Depend 2019 May 27;198:133-135. Epub 2019 Feb 27.

Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.

Objective: To understand the number of young adult people who inject drugs (PWID) with hepatitis C virus (HCV) infection accessing direct-acting antiviral (DAA) treatment and their barriers and facilitators to treatment uptake.

Methods: Using prospective cohort data from young adult PWID in San Francisco with newly identified HCV infection, we calculated the number who: (i) accepted referral to DAA therapy, (ii) initiated DAA therapy, (iii) completed DAA therapy, and (iv) achieved sustained virologic response (SVR) or cure. Behavioral survey data identified possible barriers and facilitators to DAA therapy. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.008DOI Listing

Short and long-term improvements in psychiatric symptomatology to validate clinically meaningful treatment outcomes for cocaine use disorders.

Drug Alcohol Depend 2019 May 20;198:126-132. Epub 2019 Mar 20.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.

Background: Substantial efforts have been made to identify clinically meaningful non-abstinence cocaine use outcomes by establishing associations between targeted drug use outcomes and long-term functional improvements. Psychiatric symptomatology is prevalent among those seeking treatment for cocaine use disorder (CUD). Establishing an association between cocaine use outcomes and improvements in psychiatric symptomatology would support clinical validity to these outcome measures. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.046DOI Listing
May 2019
3 Reads

Unintentional drug overdose deaths involving cocaine among middle-aged and older adults in New York City.

Drug Alcohol Depend 2019 May 14;198:121-125. Epub 2019 Mar 14.

New York City Department of Health and Mental Hygiene, United States.

Background: Cocaine is commonly involved in unintentional drug poisoning (overdose) deaths, accounting for 46% of overdose deaths in New York City (NYC) in 2016. However, little research exists regarding cocaine use by middle-aged and older adults, who are more likely than younger individuals to have underlying cardiovascular disease (CVD) and therefore, may be at increased risk for the adverse health consequences of cocaine.

Methods: We conducted a retrospective analysis of unintentional drug overdose deaths of middle-aged and older NYC residents age 45-84 from 2000 to 2016 using two linked sources, NYC death certificates and toxicology results from the Office of the Chief Medical Examiner. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193007
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467745PMC
May 2019
5 Reads

Trends in fentanyl and fentanyl analogue-related overdose deaths - Montgomery County, Ohio, 2015-2017.

Drug Alcohol Depend 2019 May 18;198:116-120. Epub 2019 Mar 18.

Department of Population and Public Health Sciences, Center for Interventions, Treatment, and Addictions Research, Boonshoft School of Medicine, Wright State University, 3171 Research Blvd, Kettering, OH, 45420, USA.

Introduction: There is a lack of information on illicitly manufactured fentanyl and fentanyl analogue-related (IMF) unintentional overdose death trends over time. The study analyzes IMF-related unintentional overdose fatalities that occurred between July 2015 and June 2017 in Montgomery County, Ohio, an area with the highest rates of unintentional overdose mortality in Ohio.

Methods: LC-MS/MS-based method was used to identify fentanyl analogs and metabolites in 724 unintentional overdose death cases. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.045DOI Listing
May 2019
1 Read

Confirmed marijuana use and lymphocyte count in black people living with HIV.

Drug Alcohol Depend 2019 May 18;198:112-115. Epub 2019 Mar 18.

University of Florida Center for AIDS/HIV Research, Service, and Education University of Florida, United States.

Background: Marijuana is a commonly used recreational substance with purported analgesic and mood enhancing properties. Many people living with HIV identify marijuana as a palliative substance. However, through its main psychoactive component, tetrahydrocannabinol (THC), is known to influence the immune system. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716183082
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http://dx.doi.org/10.1016/j.drugalcdep.2018.11.018DOI Listing
May 2019
3 Reads

Blunts versus joints: Cannabis use characteristics and consequences among treatment-seeking adults.

Drug Alcohol Depend 2019 May 14;198:105-111. Epub 2019 Mar 14.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC861, Charleston, SC, 29425, USA.

Background: Despite the high prevalence of blunt smoking among cannabis users, very few studies examine the clinical profile of blunt smokers relative to those using more common methods of cannabis use, such as joints.

Methods: The current study uses baseline data from the ACCENT (Achieving Cannabis Cessation-Evaluating N-acetylcysteine Treatment) study, a multi-site randomized pharmacotherapy clinical trial within the National Drug Abuse Treatment Clinical Trials Network, to predict the association between blunt and joint use frequency and cannabis use characteristics (e.g. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467739PMC
May 2019
2 Reads

Menstrual cycle phase modulates responses to smoking cues in the putamen: Preliminary evidence for a novel target.

Drug Alcohol Depend 2019 May 15;198:100-104. Epub 2019 Mar 15.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Background: The preclinical literature identifies the ventral striatum (VS) as a key player in drug-conditioned responses, guiding hypotheses examining neural substrates involved in human drug cue reactivity, including the study of sex differences. Men show a replicable response that includes the VS, while women's responses have been weaker and variable. New evidence suggests that the hormonal milieu modulates women's responses to drug cues in the dorsal striatum (DS), specifically, in the putamen. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467805PMC
May 2019
2 Reads

Childhood language development and later alcohol use behaviors.

Drug Alcohol Depend 2019 May 14;198:95-99. Epub 2019 Mar 14.

Department of Psychology and Neuroscience, University of Colorado, Muenzinger D244, 345 UCB, Boulder, Colorado, 80309, United States; Institute for Behavioral Genetics, University of Colorado, 1480 30th Street, Boulder, Colorado, 80303, United States.

Background: Studies have shown a correlation between language abilities and alcohol use; however, results are inconsistent. A recent study using a discordant twin design showed an association between early child language development and later alcohol use behaviors; i.e. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467720PMC
May 2019
2 Reads

Independent or synergistic? Effects of varying size and using pictorial images in tobacco health warning labels.

Drug Alcohol Depend 2019 May 1;198:87-94. Epub 2019 Mar 1.

Department of Communication, Cornell University, 450B Mann Library Building, Ithaca, NY, 14853, USA.

Introduction: Legal challenges have blocked the implementation of large, pictorial health warning labels (HWLs) in the U.S. In light of future legal questions the U. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193006
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.034DOI Listing
May 2019
4 Reads

Strategies used by people who inject drugs to avoid stigma in healthcare settings.

Drug Alcohol Depend 2019 May 8;198:80-86. Epub 2019 Mar 8.

Department of Community Health Sciences, Boston University School of Public Health, Boston, MA, United States. Electronic address:

Background: People who inject drugs (PWID) have limited engagement in healthcare services and report frequent experiences of stigma and mistreatment when accessing services. This paper explores the impact of stigma against injection drug use on healthcare utilization among PWID in the U.S. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.037DOI Listing
May 2019
1 Read

UPPS-P impulsive personality traits and adolescent cigarette smoking: A meta-analysis.

Drug Alcohol Depend 2019 Apr 19;197:335-343. Epub 2019 Feb 19.

School of Psychology, Deakin University, 225 Burwood Highway, Burwood, Victoria, 3125, Australia. Electronic address:

Background: Adolescence is a critical developmental period in the trajectory of nicotine dependence, highlighting the need for a greater understanding of the modifiable risk factors. An extensive body of research has found that trait impulsivity is associated with higher levels of adolescent smoking; however, findings have been mixed. The present study aimed to synthesise existing literature to determine the strength and nature of the relationship between the UPPS-P impulsive traits and both adolescent cigarette consumption and nicotine dependence. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.018DOI Listing

Alcohol and parenthood: An integrative analysis of the effects of transition to parenthood in three Australasian cohorts.

Drug Alcohol Depend 2019 Apr 13;197:326-334. Epub 2019 Feb 13.

Centre for Adolescent Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.

Aims: To determine the extent to which the transition to parenthood protects against heavy and problematic alcohol consumption in young men and women.

Design: Integrated participant-level data analysis from three population-based prospective Australasian cohort studies.

Setting: General community; participants from the Australian Temperament Study, the Christchurch Health and Development Study, and the Victorian Adolescent Health Cohort Study. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.004DOI Listing

Adverse childhood experiences and MSM marijuana use.

Drug Alcohol Depend 2019 May 27;198:76-79. Epub 2019 Feb 27.

Center for Health Sciences, Center for Rural Health, Oklahoma State University, 1111 W 17(th)St., Tulsa, OK, 74107, United States.

Background: Past research identified individuals who experienced adverse childhood experiences (ACEs) are at a higher risk of drug use. There is evidence to suggest that identifying as a man who has sex with other men (MSM) may increase the likelihood of drug use when adverse childhood experiences are prevalent. However, research has not addressed if this association is present in both rural and urban MSM, as other studies found that rurality/urbanity is a key determinant in detrimental outcomes for MSM. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.024DOI Listing

Predictors of timely opioid agonist treatment initiation among veterans with and without HIV.

Drug Alcohol Depend 2019 May 9;198:70-75. Epub 2019 Mar 9.

Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, UPMC Montefiore Hospital, Suite 933W, Pittsburgh, PA, 15213, USA; VA Pittsburgh Healthcare System, 4100 Allequippa St, Pittsburgh, PA, 15213, USA.

Background: Opioid use disorder (OUD) is prevalent among people with HIV (PWH). Opioid agonist therapy (OAT) is the most effective treatment for OUD and is associated with improved health outcomes, but is often not initiated. To inform clinical practice, we identified factors predictive of OAT initiation among patients with and without HIV. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193007
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.038DOI Listing
May 2019
3 Reads
3.423 Impact Factor

Everyday discrimination indirectly influences smoking cessation through post-quit self-efficacy.

Drug Alcohol Depend 2019 May 28;198:63-69. Epub 2019 Feb 28.

Oklahoma Tobacco Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Department of Family and Preventive Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Background: Although studies have shown an association between discrimination and current smoking, the influence of discrimination on smoking cessation is an understudied area in tobacco research. The current study evaluated the influence of everyday discrimination on smoking cessation and examined self-efficacy as a potential mediator of this association.

Methods: Participants (N = 146), who were recruited from a safety-net hospital in Dallas County, Texas, from 2011 to 2013, completed a self-report measure of perceived discrimination one week before the scheduled quit attempt and self-efficacy for quitting was assessed one day after the scheduled quit date. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193006
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.033DOI Listing
May 2019
5 Reads

Effects of nicotine and THC vapor inhalation administered by an electronic nicotine delivery system (ENDS) in male rats.

Drug Alcohol Depend 2019 May 27;198:54-62. Epub 2019 Feb 27.

Department of Neuroscience, The Scripps Research Institute, La Jolla, CA, USA. Electronic address:

Background: Electronic nicotine delivery systems (ENDS, e-cigarettes) are increasingly used for the self-administration of nicotine by various human populations, including previously nonsmoking adolescents. Studies in preclinical models are necessary to evaluate health impacts of ENDS including the development of nicotine addiction, effects of ENDS vehicles, flavorants and co-administered psychoactive substances such as Δ-tetrahydrocannabinol (THC). This study was conducted to validate a rat model useful for the study of nicotine effects delivered by inhalation of vapor created by ENDS. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467722PMC
May 2019
5 Reads

Prenatal drug exposure from infancy through emerging adulthood: Results from neuroimaging.

Drug Alcohol Depend 2019 May 28;198:39-53. Epub 2019 Feb 28.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06510, USA; Connecticut Mental Health Center, New Haven, CT, 06519, USA; Connecticut Council on Problem Gambling, Wethersfield, CT, 06109, USA.

Prenatal drug exposure may have important repercussions across the lifespan for cognition and behavior. While alcohol is a recognized teratogen, the influences of other substances may also be substantial. The neural underpinnings of the influences of prenatal drug exposure have been examined using longitudinal approaches and multiple imaging techniques. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.032DOI Listing

Interoceptive accuracy and interoceptive sensibility in individuals with alcohol use disorder-Different phenomena with different clinical correlations?

Drug Alcohol Depend 2019 May 8;198:34-38. Epub 2019 Mar 8.

Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland. Electronic address:

Background: Interoception may contribute to substance use disorder as it relates to the body's experience of substance use or withdrawal. However, only a few studies have directly investigated associations between interoception and alcohol use. The objective of this study was to compare individuals with alcohol use disorder (AUD) and healthy controls on interoceptive sensibility and accuracy. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467704PMC
May 2019
4 Reads

Polydrug use disorders in individuals with opioid use disorder.

Drug Alcohol Depend 2019 May 28;198:28-33. Epub 2019 Feb 28.

Addictions Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Departments of Family and Community Medicine, Pharmacology and Toxicology, and Psychiatry, Institute of Medical Sciences, University of Toronto, Toronto, Canada; Campbell Family Mental Health Research Institute, CAMH, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

Background: Understanding the association of polydrug use disorders (PUD) with psychosocial and clinical factors is essential for the treatment of individuals with opioid use disorder (OUD). The aim of this study is to examine whether there is an association between childhood maltreatment, mood disorders, anxiety disorders, personality disorders, or posttraumatic stress disorder (PTSD) and PUD in individuals with OUD.

Methods: We used data from 356 individuals with OUD in the past 12 months from a nationally representative database in the United States. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193006
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.031DOI Listing
May 2019
10 Reads

Influence of experimental alcoholism on the repair process of bone defects filled with beta-tricalcium phosphate.

Drug Alcohol Depend 2019 Apr 16;197:315-325. Epub 2019 Feb 16.

Department of Biological Sciences (Anatomy), Bauru School of Dentistry, University of São Paulo (USP), Bauru, Brazil; Medical School, University of Marilia (UNIMAR), Marília, Brazil. Electronic address:

This study evaluated the effect of ethanol on the repair in calvaria treated with beta-tricalcium phosphate (β-TCP). Forty rats were distributed into 2 groups: Water group (CG, n = 20) and Alcohol Group (AG, n = 20), which received 25% ethanol ad libitum after an adaptation period of 3 weeks. After 90 days of liquid diet, the rats were submitted to a 5. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2018.12.031DOI Listing
April 2019
1 Read

A systematic review of stakeholder perceptions of supervised injection facilities.

Drug Alcohol Depend 2019 Apr 14;197:299-314. Epub 2019 Feb 14.

University of Oxford, Department of Social Policy and Intervention, Barnett House, 32 Wellington Square, Oxford, UK.

Introduction: Supervised injection facilities (SIFs) have been developed to address the public health burden associated with substance use. While these facilities have been associated with a number of positive outcomes, stakeholder opinion (the opinions of those potentially affected by these facilities) is likely to influence their future development. This systematic review aims to answer the question, "how do stakeholders perceive SIFs?"

Materials And Methods: Articles were located through nine academic databases, by searching for grey literature, by contacting health departments in countries where SIFs have been implemented, by searching articles that cited included articles, and by searching the reference lists of included articles. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.006DOI Listing

Substance abuse and white matter: Findings, limitations, and future of diffusion tensor imaging research.

Drug Alcohol Depend 2019 Apr 13;197:288-298. Epub 2019 Feb 13.

Department of Psychology, College of Liberal Arts, Temple University, United States. Electronic address:

Individuals who abuse substances often differ from nonusers in their brain structure. Substance abuse and addiction is often associated with atrophy and pathology of grey matter, but much less is known about the role of white matter, which constitutes over half of human brain volume. Diffusion tensor imaging (DTI), a method for non-invasively estimating white matter, is increasingly being used to study addiction and substance abuse. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440853PMC
April 2019
1 Read

Perceived harmfulness of various alcohol- and cannabis use modes: Secular trends, differences, and associations with actual substance use behaviors among Norwegian adolescents, 2007-2015.

Drug Alcohol Depend 2019 Apr 13;197:280-287. Epub 2019 Feb 13.

Norwegian Institute of Public Health, Department of Alcohol, Tobacco, and Drugs, Postboks 222, Skøyen, 0213 Oslo, Norway. Electronic address:

Background: How youth perceive harmfulness of risk behaviors such as substance use relates to their engagement in those behaviors. Yet, little is known about how different substance use modes (i.e. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.003DOI Listing
April 2019
1 Read

Association between polygenic risk for tobacco or alcohol consumption and liability to licit and illicit substance use in young Australian adults.

Drug Alcohol Depend 2019 Apr 16;197:271-279. Epub 2019 Feb 16.

Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia; Department of Psychology, Michigan State University, East Lansing, MI, USA.

Background: Co-morbid substance use is very common. Despite a historical focus using genetic epidemiology to investigate comorbid substance use and misuse, few studies have examined substance-substance associations using polygenic risk score (PRS) methods.

Methods: Using summary statistics from the largest substance use GWAS to date (258,797- 632,802 subjects), GWAS and Sequencing Consortium of Alcohol and Nicotine use (GSCAN), we constructed PRSs for smoking initiation (PRS-SI), age of initiation of regular smoking (PRS-AI), cigarettes per day (PRS-CPD), smoking cessation (PRS-SC), and drinks per week (PRS-DPW). Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.015DOI Listing
April 2019
1 Read

Non drug-related and opioid-specific causes of 3262 deaths in Scotland's methadone-prescription clients, 2009-2015.

Drug Alcohol Depend 2019 Apr 19;197:262-270. Epub 2019 Feb 19.

MRC Biostatistics Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0SR, United Kingdom; University of Edinburgh Centre for Medical Informatics, Edinburgh EH16 4UX, United Kingdom. Electronic address:

Background: Opioid drug use is a major cause of premature mortality, with opioid substitution therapy the leading intervention. As methadone-clients age, non-drug-related deaths (non-DRDs) predominate and DRD-risks increase differentially, quadrupling at 45+ years for methadone-specific DRDs.

Methods: 36,606 methadone-prescription-clients in Scotland during 2009-2015 were linked to mortality records to end-2015 by their Community Health Index (CHI). Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445802PMC
April 2019
1 Read

The role of neurocognitive functioning, substance use variables and the DSM-5 severity scale in cocaine relapse: A prospective study.

Drug Alcohol Depend 2019 Apr 16;197:255-261. Epub 2019 Feb 16.

Grupo Interdisciplinar de Estudos de Álcool e Drogas GREA, Instituto de Psiquiatria IPq, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, R. Dr. Ovídio Pires de Campos, 785, Cerqueira César, 01060-970, Sao Paulo, SP, Brazil; Laboratorio de Neuroimagem em Psiquiatria (LIM 21), Instituto de Psiquiatria IPq, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, R. Dr. Ovídio Pires de Campos, 785, Cerqueira César, 01060-970, Sao Paulo, SP, Brazil.

Background: The severity of substance use disorder (SUD) is currently defined by the sum of DSM-5 criteria. However, little is known about the validity of this framework or the role of additional severity indicators in relapse prediction. This study aimed to investigate the relationship between DSM-5 criteria, neurocognitive functioning, substance use variables and cocaine relapse among inpatients with cocaine use disorder (CUD). Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.013DOI Listing
April 2019
2 Reads

Identifying opioid prescribing patterns for high-volume prescribers via cluster analysis.

Drug Alcohol Depend 2019 Apr 16;197:250-254. Epub 2019 Feb 16.

Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, United States.

Objective: Despite recent decreases in opioid prescribing rates, evidence suggests there is substantial variation in the way opioids are prescribed by providers. This study aims to identify patterns in high-volume opioid prescribing.

Methods: We conducted partitioning-around-medoids cluster analysis using the IQVIA Prescriber Profile dataset, including the number of opioid prescriptions filled at US retail pharmacies aggregated at the prescriber-level from July 2016 through June 2017. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476423PMC