2,102 results match your criteria Drooling


[Medicaments and oral healthcare. Systematic review of the -literature assessing the effect of drugs on the salivary glands].

Ned Tijdschr Tandheelkd 2018 Nov;125(11):593-601

Evidence-based reviews of drugs causing medication-induced salivary gland dysfunction, such as xerostomia (sensation of oral dryness) and subjective sialorrhea are lacking. To compile a list of medicaments that influence salivary gland function, electronic databases were searched for relevant articles published up to June 2013. A total of 269 papers out of 3,867 records located satisfied the inclusion criteria (relevance, quality of methodology, strength of evidence). Read More

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November 2018

Onabotulinum Toxin A Injections Into the Salivary Glands for Spinal Muscle Atrophy Type I: A Prospective Case Series of 4 Patients.

Am J Phys Med Rehabil 2018 Dec;97(12):873-878

From the Children's Specialized Hospital, Clifton, New Jersey (HAS); Touro College, Executive Office, New York, New York (EA); Cornell University Joan and Sanford I Weill Medical College, New York, New York (AH); New York-Presbyterian Hospital, New York, New York (XW, PT, RA, HK); and Blythedale Children's Hospital, New York, New York (XW, PT, RA, HK).

Objective: The aim of the study was to investigate the safety and efficacy of onabotulinum toxin A injection to the salivary glands under ultrasound guidance for the treatment of sialorrhea in patients with spinal muscular atrophy type I.

Design: Prospective case series with four patients with spinal muscular atrophy type I who received onabotulinum toxin A injection to parotid and submandibular glands for sialorrhea as part of clinical care. All four patients received validated surveys for measuring drooling, including objective measures of number of bib changes, and number of mouth wipes before injection and 4-6 wks after injection. Read More

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December 2018

Aesthetic and Functional Evaluation of Large Full-Thickness Vermilion and Lower Lip Defects Reconstruction.

J Craniofac Surg 2018 Oct 29. Epub 2018 Oct 29.

Department of Stomatology, Sichuan Provincial Academy of Medical Sciences, Affiliated Hospital to School of Medicine, University of Electronic Science and Technology of China (UESTC), Sichuan Provincial People's Hospital.

Background: It is hardly to reconstruct a huge defect of lower lip by using of partial flap which brings no mouth closing functional problem. In this study, we would like to introduce our experience in large full-thickness vermilion and lower lip/chin defects reconstruction, and also focus on the evaluation of the surgery effects.

Methods: The large lower lip and chin (include vermilion) reconstruction were performed in Sichuan Provincial People's Hospital (2012-2015). Read More

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October 2018
1 Read
0.680 Impact Factor

Pediatric Sialorrhea: Submandibular Duct Rerouting and Intraparotid Botulinum Toxin A Injection With Literature Review.

Ann Otol Rhinol Laryngol 2018 Oct 29:3489418808305. Epub 2018 Oct 29.

1 Faculty of Medicine, Department of Otolaryngology, Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey.

Objectives:: The aim of this study was to assess the effectiveness of bilateral submandibular duct relocation and bilateral sublingual gland excision in combination with botulinum toxin A injection into the parotid glands in children with sialorrhea. Previously in the literature, either surgery or botulinum toxin injection but not their combination has been reported.

Methods:: Preoperative and at least 6-month postoperative assessments using the Drooling Severity Scale and Drooling Frequency Scale (Thomas-Stonell and Greenberg classification) and the Teacher Drooling Scale and by interviewing parents and caregivers face to face or via telephone were performed. Read More

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October 2018

A Retrospective Multicenter Evaluation of Clozapine Use in Pediatric Patients Admitted for Acute Psychiatric Hospitalization.

J Child Adolesc Psychopharmacol 2018 Nov 24;28(9):615-619. Epub 2018 Oct 24.

10 Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.

Objectives: Clozapine is the drug of choice for treatment-resistant schizophrenia. While pediatric clozapine use is not contraindicated, the literature describing its clinical application is limited. The primary objective of this study was to assess the use of clozapine in a child and adolescent population by characterizing the documented safety and clinical benefits of the medication. Read More

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November 2018
4 Reads
2.930 Impact Factor

A Lot to Choke on: Case of Adult Epiglottitis with Concurrent Peritonsillar Abscess in a Patient with a Sore Throat.

J Emerg Med 2018 Oct 17. Epub 2018 Oct 17.

University of California San Diego, San Diego, California.

Background: In the winter months, one often sees a large increase in the volume of patients presenting to emergency departments with acute pharyngitis. While most cases of acute pharyngitis are benign, a rare minority can be life threatening.

Case Report: We report a case of epiglottis with a concomitant peritonsillar abscess (PTA) in an adult who presented to the emergency department with a sore throat. Read More

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October 2018
9 Reads

Salivary lead concentration in dental caries among normal and children with cerebral palsy.

J Indian Soc Pedod Prev Dent 2018 Oct-Dec;36(4):381-385

Department of ENT, Al Ameen Medical College and Hospital, Vijayapur, Karnataka, India.

Introduction: Cerebral palsy (CP) is a neurological disability the exact cause of which is not known. Exposure to toxic elements, environmental pollutants, and various teratogens such as lead, either prenatal or postnatal, can be a risk factor for this neurologic disability. CP children have poor neuromuscular coordination, exposing them to increased risk of oral diseases such as drooling of saliva, periodontal diseases, dental caries, and malocclusion. Read More

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October 2018
7 Reads

[Salivary management in amyotrophic lateral sclerosis].

Rev Med Suisse 2018 Oct;14(621):1758-1762

Unité de phoniatrie, Service d'ORL et de chirurgie cervico-faciale, CHUV, 1011 Lausanne.

80 % of patients suffering from amyotrophic lateral sclerosis present bulbar involvement and 50 % have salivary symptoms, which are often poorly managed. They present either with drooling or thick secretions. This elevates the risk of bronchoaspiration leading to pneumonia, second cause of death in this population. Read More

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October 2018
4 Reads

Oral Sensory-Motor Intervention for Children and Adolescents (3-18 Years) With Dysphagia or Impaired Saliva Control Secondary to Congenital or Early-Acquired Disabilities: A Review of the Literature, 2000 to 2016.

Ann Otol Rhinol Laryngol 2018 Dec 8;127(12):978-985. Epub 2018 Oct 8.

7 Division of Speech and Language Pathology, CLINTEC, Karolinska Institutet, Functional Area Speech and Language Pathology, Karolinska University Hospital, Stockholm, Sweden.

Objectives:: Dysphagia and impaired saliva control are common in children and adolescents with congenital and developmental disabilities. The aim of the present review was to investigate the evidence base for oral sensory-motor interventions in children and adolescents with dysphagia or impaired saliva control secondary to congenital or early-acquired disabilities and to make recommendations regarding methods for intervention.

Methods:: A review of the literature from 2000 to 2016, including oral sensory-motor intervention studies for children and adolescents (3-18 years of age) with dysphagia or impaired saliva control secondary to congenital or early-acquired disabilities, was performed. Read More

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December 2018
1 Read

Staged lower lip reconstruction following gangrenous stomatitis in an immunosuppressed patient.

Arch Craniofac Surg 2018 Sep 20;19(3):222-226. Epub 2018 Sep 20.

Department of Plastic and Reconstructive Surgery, Myongji Hospital, Goyang, Korea.

A 70-year-old male with a history of diabetes mellitus, hypertension, and coronary stent insertion visited our hospital 7 days after biting his lower lip. Swelling and inflammation had worsened despite debridement and antibiotic treatment. On the 8th hospital day, fungal infection with Candida albicans and superimposed bacterial infection with Klebsiella pneumoniae were found on tissue culture. Read More

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September 2018
1 Read

Behavioural interventions to treat drooling in children with neurodisability: a systematic review.

Dev Med Child Neurol 2018 Oct 1. Epub 2018 Oct 1.

School of Allied Health and Centre for Disability and Development Research at the Australian Catholic University, Melbourne, Victoria, Australia.

Aim: To review the evidence for behavioural interventions to reduce drooling in children with neurodisability.

Method: A detailed search in eight databases sought studies that: (1) included participants aged 0 to 18 years with neurodisability and drooling; (2) provided behavioural interventions targeting drooling or a drooling-related behaviour; and (3) used experimental designs. Two reviewers extracted data from full-text papers independently. Read More

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October 2018
9 Reads

Reconstruction of a subtotal upper lip defect with a facial artery musculomucosal flap, kite flap, and radial forearm free flap: a case report.

World J Surg Oncol 2018 Sep 28;16(1):194. Epub 2018 Sep 28.

Department of Oromaxillofacial-Head and Neck Surgery, No. 117, Nanjing North Street, Heping District, Shenyang, Liaoning, 110002, People's Republic of China.

Background: For reconstructive surgeons, massive midface defects, including large, full-thickness wounds on the upper lip, can be very challenging. Although there are many methods for reconstruction of upper lip defects, it is difficult to obtain satisfactory restoration of oral functions and good cosmetic results.

Case Presentation: This case report presents a man with massive midface defects, including upper lip, left nose, and cheek defects. Read More

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September 2018
10 Reads

[Endoscopic management of gastric volvulus in a 8-years old girl].

Cir Pediatr 2018 Aug 3;31(3):153-157. Epub 2018 Aug 3.

Hospital Guillermo Grant Benavente. Facultad de Medicina, Universidad de Concepción. Chile.

Introduction: Gastric volvulus is a rare cause of acute abdomen in childhood, and it is usually a casual finding. We present the case of a girl with mesenteroaxial gastric volvulus, which was initially treated by endoscopic approach.

Clinical Case: 8 year-old patient, diagnosed of Down syndrome, who presented sudden and diffuse colic pain, associated with vomiting, sialorrhea and progressive compromise. Read More

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August 2018
1 Read

Misconceptions and traditional practices towards infant teething symptoms among mothers in Southwest Ethiopia.

BMC Oral Health 2018 Sep 21;18(1):159. Epub 2018 Sep 21.

Department of Public Health, St. Paul Hospital's Millennium Medical College, Addis Ababa, Ethiopia.

Background: The assumption of a link between common symptoms such as febrile illness, diarrhea and the eruption of primary teeth has been established over many centuries. According to traditional beliefs in Ethiopia, diarrhea and fever at the time of milk teeth eruption may be due to a worm in the child's gums. Current medical observations show little more than restlessness, drooling, and finger sucking resulting from teething. Read More

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September 2018
3 Reads

Treatment of drooling with scopolamine in pediatric ICU: A case series report.

Spec Care Dentist 2018 Nov 20;38(6):362-366. Epub 2018 Sep 20.

Division of Dentistry, Hospital das Clinicas, Medical School, University of São Paulo, São Paulo, Brazil.

Drooling is a condition that affects patients with difficulties in swallowing, being common in patients with mental, neurological or dysphagic deficiency. This condition is difficult to diagnose, as it is often confused with sialorrhea, and in many cases we have a hyposalivation scenario. Its diagnosis is subjective, which is why scales should be used for the standardization of the evaluation of the degree of drooling before and after the proposed treatment, as the Thomas-Stonell and Greenberg scale. Read More

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November 2018
4 Reads

Honey can help in herpes simplex gingivostomatitis in children: Prospective randomized double blind placebo controlled clinical trial.

Am J Otolaryngol 2018 Nov - Dec;39(6):759-763. Epub 2018 Sep 12.

Otolaryngology, Head and Neck Department, Minia University Hospital, Minia, Egypt.

Purpose: Herpes simplex gingivostomatitis (HSGS) in children is a common painful infectious disease. This study aims to examine the combined efficacy of honey with acyclovir suspension compared to acyclovir alone for treating HSGS in young children.

Material And Methods: This Randomized double blind placebo controlled study was conducted from June 2015 to September 2017 in a tertiary referral hospital. Read More

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September 2018
11 Reads

Bell's palsy treated with photobiomodulation in an adolescent: Rare case report and review of the published literature.

Int J Paediatr Dent 2018 Nov 14;28(6):658-662. Epub 2018 Sep 14.

Department of Clinic and Surgery, School of Dentistry, Federal University of Alfenas, Alfenas, MG, Brazil.

Background: Bell's palsy represents a peripheral unilateral facial nerve paralysis, being an acute, idiopathic disorder, which can affect children and adolescents. Some therapeutic approaches have been proposed including facial exercises, biofeedback, photobiomodulation, electrotherapy, massage, and thermotherapy. The present report documents a rare case of Bell's palsy in an adolescent successfully treated with a new protocol of photobiomodulation, consisting of a short-term treatment. Read More

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November 2018
12 Reads

Unsuspected Cause of Respiratory Distress: Unrecognized Esophageal Foreign Body.

Case Rep Pediatr 2018 19;2018:6283053. Epub 2018 Aug 19.

Department of Emergency Unit, Mother and Child Hospital, Mohammed VI University Hospital, Faculty of Medicine, Cadi Ayyad University, Marrakech, Morocco.

Summary: Foreign bodies in esophagus are avoidable accidents that occur most often in children younger than 3 years. The most common presenting symptoms are dysphagia, drooling, and vomiting. Revelation by respiratory distress is a rare and unusual condition. Read More

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August 2018
4 Reads

The Effectiveness of Botulinum Toxin Type A Injections in the Management of Sialorrhea.

Turk Arch Otorhinolaryngol 2018 Jun 1;56(2):111-113. Epub 2018 Jun 1.

Department of Otorhinolaryngology, Çukurova University School of Medicine, Adana, Turkey.

Objective: The aim of this study was to evaluate the effect of Botulinum toxin type A by injecting in the submandibular and parotid glands on the frequency and severity of sialorrhea.

Methods: Pediatric patients who were referred to our department with sialorrhea were evaluated using their parents' frequency and severity scores of sialorrhea with visual analog scales before and after 3 months of botulinum toxin type A injections. Bilateral submandibular and parotid glands were injected with Botulinum toxin type A. Read More

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June 2018
6 Reads

Management of common adverse effects of antipsychotic medications.

World Psychiatry 2018 Oct;17(3):341-356

Department of Psychiatry, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.

The benefits of antipsychotic medications are sometimes obscured by their adverse effects. These effects range from relatively minor tolerability issues (e.g. Read More

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October 2018
1 Read

Dihydroergotoxine mesylate for the treatment of sialorrhea in Parkinson's disease.

Parkinsonism Relat Disord 2018 Aug 30. Epub 2018 Aug 30.

Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China. Electronic address:

Background: Many patients with Parkinson's disease (PD) suffer from sialorrhea. Sialorrhea is often treated with anticholinergics and botulinum toxin, but some adverse effects have limited the use of these treatments. Dihydroergotoxine mesylate is an α-adrenergic blocking agents as well as some affinities to the dopaminergic and serotonin (5-HT) receptors. Read More

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August 2018
5 Reads

Submandibular duct transposition for drooling in children: A Casuistic review and evaluation of grade of satisfaction.

Int J Pediatr Otorhinolaryngol 2018 Oct 17;113:58-61. Epub 2018 Jul 17.

ENT Department, Centro Hospitalar Tondela Viseu, Portugal. Electronic address:

Introduction: Drooling of saliva is the unintentional loss of saliva from the mouth resulting in excess pooling of saliva in the anterior portion of the oral cavity. It is considered normal in infants and usually resolves itself by 15-18 months of age. It is a common problem in pediatric patients with cerebral palsy or other neurological disorders. Read More

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October 2018
2 Reads

The phenotype of developmental and epileptic encephalopathy.

Neurology 2018 Sep 31;91(12):e1112-e1124. Epub 2018 Aug 31.

From the Department of Clinical Neurophysiology (E.G., S.B.), Danish Epilepsy Centre, Dianalund; Institute for Regional Health Services (E.G., K.M.J., R.S.M.), University of Southern Denmark, Odense, Denmark; Neuroscience Department (C.M., R.G., M.M.), Children's Hospital A. Meyer, University of Florence; Department of Neuroscience (M.T., N.S., F.V.), Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Division of Neurology (M.P.F., I.H.), The Children's Hospital of Philadelphia; Departments of Pediatrics and Neurology (M.P.F., I.H.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Universitätskinderklinik Tübingen (M.A., M.W.), Germany; Department of Neurology (K.H.), Royal Children's Hospital Melbourne; Department of Paediatrics (K.H.), University of Melbourne; Australia Neurosciences Group (K.H.), Murdoch Children's Research Institute, Melbourne, Australia; Servizio di Neuropsichiatria Infantile (F.D., E.F.), Policlinico G.B. Rossi, Universita Degli Studi di Verona; Department of Child Neurology (S.S., G.A.), Ospedale Pediatrico G. Salesi-Ospedali Riuniti, Ancona, Italy; Division of Clinical Neurophysiology (B.B.), Children's Research Center, University Children's Hospital Zurich, Switzerland; Brain and Behaviour Department (S.M.), University of Pavia; Department of Pediatric Neuroradiology (A.P.), IRCCS "C. Mondino" National Neurological Institute, Pavia, Italy; Department of Epilepsy Genetics (K.J., R.S.M.), Danish Epilepsy Centre Dianalund; Department of Child Neurology (B.J.), Danish Epilepsy Centre, Dianalund, Denmark; Cytogenetic and Molecular Genetic Laboratory (S.R., F.C.), Istituto Auxologico Italiano, IRCCS, Milano, Italy; Department of Adult Neurology (G.R.), Danish Epilepsy Centre, Dianalund; University of Copenhagen (G.R.), Denmark; Struttura Complessa di Neurologia Pediatrica Ospedale Vittore Buzzi (P.V.), Milano; Dipartimento di Scienze Biomediche e Cliniche L. Sacco (P.V.), Università di Milano, Italy; Århus University (S.B.), Denmark; Department of Child Neurology (I.E.S.), University of Melbourne, Austin Health, Florey Institute; and Department of Child Neurology (I.E.S.), The Royal Children's Hospital, Melbourne, Australia.

Objective: To delineate the electroclinical features of infantile developmental and epileptic encephalopathy (EIEE13, OMIM #614558).

Methods: Twenty-two patients, aged 19 months to 22 years, underwent electroclinical assessment.

Results: Sixteen of 22 patients had mildly delayed development since birth. Read More

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September 2018
5 Reads

Worster-Drought Syndrome Associated With Mutations.

Child Neurol Open 2018 2;5:2329048X18791083. Epub 2018 Aug 2.

Department of Genetics, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

Worster-Drought syndrome is a congenital, pseudobulbar paresis. There is no identified molecular etiology despite familial cases reported. The authors report a boy who was diagnosed with Worster-Drought syndrome due to longstanding drooling, dysphagia, and impaired tongue movement. Read More

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August 2018
9 Reads

Validation of a drooling questionnaire in Indian children with cerebral palsy.

Int J Pediatr Otorhinolaryngol 2018 Sep 19;112:55-60. Epub 2018 Jun 19.

-Department of ENT, Christian Medical College, Vellore, 632004, India.

Background: Drooling of saliva is a common problem in children with cerebral palsy. In addition to causing impairment in articulation, drooling also affects socialization, interpersonal relationships and integration into society for these children. There are various methods to assess drooling which measure directly the amount of saliva drooled. Read More

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September 2018
11 Reads

Circadian rhythms and influencing factors of xerostomia among Parkinson's disease patients.

Oral Dis 2018 Jul 20. Epub 2018 Jul 20.

Department of Operative Dentistry and Periodontology, Centre of Dental Medicine, University of Cologne, Köln, Germany.

Objectives: Parkinson's disease (PD) patients suffer from xerostomia, but limited information exists regarding associations with dysphagia, drooling, daily habits, PD characteristics, or possible circadian rhythms.

Subjects And Methods: A questionnaire was administered, including (a) clinical characteristics (comorbidities, prescribed medications, levodopa equivalent daily dose [LEDD], disease duration); (b) self-assessment of dysphagia, xerostomia, drooling (10-cm visual analogue scale [VAS]); (c) 24-hr diary of motor impairment, dyskinesia, xerostomia, dysphagia, drooling, daily habits.

Results: Of 75 PD patients who completed the study, 67% reported dysphagia (mean ± standard deviation VAS 4 ± 2), 76% drooling (5 ± 2), 77% xerostomia (5 ± 2). Read More

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July 2018
5 Reads

Effectiveness of submandibular duct relocation in 91 children with excessive drooling: A prospective cohort study.

Clin Otolaryngol 2018 Dec 9;43(6):1471-1477. Epub 2018 Aug 9.

Department of Otolaryngology-Head and Neck Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

Objective: To evaluate the effectiveness of submandibular duct relocation (SMDR) in drooling children with neurological disorders.

Design: Prospective cohort study.

Setting: Academic Outpatient Saliva Control Clinic. Read More

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December 2018
17 Reads

Outcomes in Head and Neck Resections That Require Multiple-Flap Reconstructions: A Systematic Review.

JAMA Otolaryngol Head Neck Surg 2018 Aug;144(8):746-752

Department of Otolaryngology-Head and Neck Surgery, Stanford University, Stanford, California.

Importance: Complex head and neck cancer defects that require multiflap reconstructions are technically feasible, but the morbidity and patient outcomes of such large-scale head and neck operations have yet to be systematically reviewed.

Objective: To systematically review existing literature to characterize the outcomes of large-scale head and neck resections that require multiple-flap reconstructions (defined as defects that require >1 flap [free, pedicled, or combinations thereof]).

Evidence Review: Two authors independently searched PubMed, Embase, and the Cochrane Review databases for English-only texts published on any date. Read More

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August 2018
10 Reads

Pediatric food impaction detected through point-of-care ultrasonography.

Clin Exp Emerg Med 2018 Jun 29;5(2):135-137. Epub 2018 Jun 29.

Division of Pediatric Emergency Medicine, Department of Pediatric Emergency and Critical Care Medicine, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

A previously healthy 1-year-old boy suddenly began coughing while eating a dried sweet potato. Because he continued gagging after vomiting a piece of the dried sweet potato, his mother brought him to our emergency room. Upon arrival, despite normal pulmonary findings, he was drooling and gagging. Read More

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June 2018
3 Reads

Laparoscopic Greater Curvature Plication and Laparoscopic Sleeve Gastrectomy Treatments for Obesity: Systematic Review and Meta-Analysis of Short- and Mid-Term Results.

Obes Surg 2018 Oct;28(10):3199-3212

Gastrointestinal Endoscopy Unit, Gastroenterology Department, University of São Paulo, CEP, São Paulo, SP, 05403-900, Brazil.

Background: Laparoscopic greater curvature plication (LGP) has recently emerged as a new bariatric procedure. This surgery provides gastric restriction without resection, which could potentially provide a lower risk alternative, with fewer complications. The real benefit of this technique in the short and long term is unknown. Read More

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October 2018
16 Reads

Paraneoplastic cerebellar degeneration with bilateral facial palsy: a rare primary presentation of breast cancer.

BMJ Case Rep 2018 Jun 21;2018. Epub 2018 Jun 21.

Department of Neurology, G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

Paraneoplastic cerebellar degeneration is a rare dysfunction of the cerebellum associated with malignancy. Nevertheless, it is the most common paraneoplastic syndrome affecting the brain. A 50-year-old woman presented to the neurology outpatient department (OPD) with symptoms of cerebellar dysfunction since 4 months and complaints of a painless lump in the right breast and drooling from mouth since 1 month. Read More

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June 2018
17 Reads

Onabotulinumtoxin-A injections into the salivary glands for spinal muscle atrophy type I: A prospective case series of four patients.

Am J Phys Med Rehabil 2018 Jun 18. Epub 2018 Jun 18.

New York-Presbyterian Hospital, 180 Fort Washington Ave, Harkness Pavilion, St 1-165, New York, NY 10032, Fax 212-342-1470.

Objective: To investigate the safety and efficacy of Onabotulinum Toxin-A (BTX-A) injection to the salivary glands under ultrasound guidance for the treatment of sialorrhea in patients with spinal muscular atrophy type I (SMA I).

Design: Prospective case series with four patients with SMA I who received BTX-A injection to parotid and submandibular glands for sialorrhea as part of clinical care. All four patients received validated surveys for measuring drooling, including objective measures of number of bib changes, and number of mouth wipes before injection and 4-6 weeks after injection. Read More

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June 2018
15 Reads

MANDIBULAR SQUAMOUS CELL CARCINOMA IN A ROCK HYRAX ( PROCAVIA CAPENSIS).

J Zoo Wildl Med 2018 Jun;49(2):489-492

  A 9-yr-old, entire female captive rock hyrax ( Procavia capensis) was presented with a 1-wk history of sialorrhea. On clinical examination, a mass was identified, encompassing the rostral mandible and intermandibular area, with associated mucosal ulceration, marked gingival recession, and loosening or loss of adjacent teeth. Skull radiography and cytology of fine-needle aspirates of the mass were suggestive of squamous cell carcinoma. Read More

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June 2018
22 Reads

[Side Effects of Smoking Cessation].

Praxis (Bern 1994) 2018 Jun;107(12):655-657

1 Psychiatrische Klinik, Regionalspital Emmental, Langnau im Emmental.

Side Effects of Smoking Cessation Abstract. We present the case of a clozapine intoxication associated with aspiration pneumonia due to smoking cessation. Clozapine is mainly metabolized by CYP1A2. Read More

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June 2018
2 Reads

Health-Related Quality of Life for Patients With Genetically Determined Leukoencephalopathy.

Pediatr Neurol 2018 Jul 9;84:21-26. Epub 2018 Apr 9.

Department of Medical Genetics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada; Department of Pediatrics, McGill University, Montreal, Quebec, Canada; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

Background: We attempted to characterize the health-related quality of life in patients with genetically determined leukoencephalopathies as it relates to the severity of clinical features and the presence or absence of a precise molecular diagnosis.

Methods: Health-related quality of life was assessed using the Pediatric Quality of Life Inventory model (Pediatric Quality of Life Inventory 4.0 Self- and Proxy-reports) on 59 patients diagnosed with genetically determined leukoencephalopathies. Read More

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July 2018
6 Reads

Incobotulinumtoxin A for Sialorrhea in Neurological Disorders: A Real-Life Experience.

Toxins (Basel) 2018 May 28;10(6). Epub 2018 May 28.

Department of Neurology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.

Botulinum toxin type A is one of the most useful treatments of sialorrhea in neurological disorders. Evidence for the use of incobotulinumtoxin A (inco-A) in the treatment of sialorrhea is limited. Thirty-six patients with sialorrhea were treated with infiltrations of inco-A into both parotid glands. Read More

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May 2018
13 Reads
2.480 Impact Factor

Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine.

Ther Adv Drug Saf 2018 May 6;9(5):237-256. Epub 2018 Feb 6.

Department of Neuroscience, Imaging and Clinical Science, Chair of Psychiatry, University 'G. D'Annunzio', Chieti, Italy.

Clozapine, a dibenzodiazepine developed in 1961, is a multireceptorial atypical antipsychotic approved for the treatment of resistant schizophrenia. Since its introduction, it has remained the drug of choice in treatment-resistant schizophrenia, despite a wide range of adverse effects, as it is a very effective drug in everyday clinical practice. However, clozapine is not considered as a top-of-the-line treatment because it may often be difficult for some patients to tolerate as some adverse effects can be particularly bothersome (i. Read More

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May 2018
41 Reads
1 Citation

A food bolus obstructing the oesophagus in a patient with infantile cerebral palsy.

Malays Fam Physician 2018 30;13(1):34-36. Epub 2018 Apr 30.

MD, M.Med (ORL-HNS), Department of Otorhinolaryngology-Head & Neck Surgery, Universiti Sains Malaysia Health Campus Kota Bharu, Kelantan, Malaysia.

Introduction: A foreign body (FB) in the upper aerodigestive tract is a fairly common encounter. Fish bones are the commonest FB seen in adults. The commonest presentation is odynophagia. Read More

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April 2018
3 Reads

An oesophageal spring.

J Int Med Res 2018 Jul 22;46(7):2938-2943. Epub 2018 May 22.

3 Pediatric Emergency Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Oesophageal foreign bodies (OFBs) are a relatively common emergency in young children. OFBs are complicated by significant morbidity and mortality because their ingestion often occurs without witnesses, leading to a delay in diagnosis and treatment. We report an occult OFB in an 11-month-old infant who initially presented without any specific respiratory symptoms, mimicking a respiratory infection. Read More

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July 2018
11 Reads

Drooling in Parkinson's Disease: Evidence of a Role for Divided Attention.

Dysphagia 2018 Dec 21;33(6):809-817. Epub 2018 May 21.

Northumbria Health NHS Foundation Trust, North Tyneside District Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK.

Drooling is a frequently reported symptom in Parkinson's Disease (PD) with significant psychosocial impact and negative health consequences including silent aspiration of saliva with the associated risk of respiratory infections. It is suggested that in PD drooling is associated with inefficient oropharyngeal swallowing which reduces the effective clearance of saliva rather than hyper-salivation. This is compounded by unintended mouth opening and flexed posture increasing anterior loss of saliva. Read More

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December 2018
7 Reads

Ocular involvement in neurolymphomatosis.

Am J Ophthalmol Case Rep 2018 Jun 2;10:148-151. Epub 2018 Mar 2.

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

Purpose: To describe the ophthalmic symptoms and histopathological findings in a case of primary neurolymphomatosis (NL).

Observations: A man in his 60s with a prior diagnosis of chronic inflammatory demyelinating polyneuropathy developed facial numbness, diplopia, drooling, and difficulty swallowing. Over a 3-month period, he developed total ptosis and ophthalmoplegia of the right eye with a dilated, non-reactive pupil considered secondary to cranial nerve III and VI palsies. Read More

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Swallowing and Secretion Management in Neuromuscular Disease.

Clin Chest Med 2018 Jun;39(2):449-457

Department of Otolaryngology-Head & Neck Surgery, Oregon Health & Science University (OHSU), Northwest Clinic for Voice and Swallowing, Physician's Pavilion 250/PV01, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

Neuromuscular disease frequently leads to dysphagia and difficulty managing secretions. Dysphagia may lead to medical complications, such as malnutrition, dehydration, aspiration pneumonia, and other pulmonary complications, as well as social isolation and reduced overall quality of life. This review provides an overview of dysphagia associated with neuromuscular disease in adults, along with a concise review of swallowing assessment and intervention options. Read More

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June 2018
3 Reads

Exposures to Single-Use Detergent Sacs Reported to a Statewide Poison Control System, 2013-2015.

Pediatr Emerg Care 2018 May 2. Epub 2018 May 2.

UCSF School of Pharmacy, San Francisco, CA.

Background: Single-use detergent sacs (SUDSs) represent a relatively new household hazard to children. Brand differences and packaging changes may contribute to differential risks with accidental exposure. We sought to identify high-risk features from SUDS exposures in children and to assess whether product packaging changed trends in SUDS exposures reported to poison centers. Read More

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Measuring lip force by oral screens. Part 1: Importance of screen size and individual variability.

Clin Exp Dent Res 2017 Jun 27;3(3):87-92. Epub 2017 Apr 27.

Department of Signals and Systems Chalmers University of Technology Sweden.

To reduce drooling and facilitate food transport in rehabilitation of patients with oral motor dysfunction, lip force can be trained using an oral screen. Longitudinal studies evaluating the effect of training require objective methods. The aim of this study was to evaluate a method for measuring lip strength, to investigate normal values and fluctuation of lip force in healthy adults on 1 occasion and over time, to study how the size of the screen affects the force, to evaluate the most appropriate measure of reliability, and to identify force performed in relation to gender. Read More

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Effectiveness of Manual Treatment on Pregnancy Symptoms: Usefulness of Manual Treatment in Treating Pregnancy Symptoms.

Authors:
Boris Skarica

Med Arch 2018 Apr;72(2):131-135

Objectives: To determine the usefulness of manual treatment in reducing or eliminating pregnancy symptoms during first and second trimester.

Methods: Manual treatment of the cervical and thoracic spine was performed in a group of 115 pregnant women who developed pregnancy symptoms during normal pregnancy. A rotational traction of the cervical spine was applied. Read More

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A Mixed Presentation of Serotonin Syndrome vs Neuroleptic Malignant Syndrome in a 12-Year-Old Boy.

Pediatr Emerg Care 2018 Apr 24. Epub 2018 Apr 24.

Department of Child and Adolescent Psychiatry, University of California San Diego, San Diego, CA.

Background: Neuroleptic malignant syndrome (NMS) and serotonin syndrome (SS) are serious medical conditions associated with commonly prescribed psychiatric medications. Although the mechanisms differ, they can be clinically difficult to distinguish. We report a case of a pediatric patient with complicated psychiatric history that developed features of both syndromes in the setting of polypharmacy. Read More

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April 2018
3 Reads

Respiratory Care in Neuromuscular Diseases.

Respir Care 2018 May 24;63(5):601-608. Epub 2018 Apr 24.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine.

Caring for patients with neuromuscular disease (NMD) is challenging. Respiratory care is of the utmost importance because it is a major determinant of quality of life and survival. Noninvasive ventilation (NIV) is one of the few modalities that has shown survival benefit in the NMD patient population. Read More

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Caustic Ingestion in Children in South of Iran: A Two-Year Single Center Study.

Middle East J Dig Dis 2018 Jan 3;10(1):31-34. Epub 2018 Jan 3.

Research Center for Infectious Diseases of Digestive System [Alimentary Tract Research Center], Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

BACKGROUND Caustic ingestion is one of the most important injuries during childhood, which leads to serious sequel. In this study, we evaluated the clinical manifestations, endoscopic appearance, complications, and treatment results in patients with caustic ingestion in our hospital. METHODS Hospital chart of patients with caustic ingestion who admitted to Nemazee Teaching Hospital affiliated to Shiraz University of Medical Sciences during a 2-year period (2015-2016) were reviewed retrospectively. Read More

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January 2018
19 Reads

Surgical Management of the Drooling Child.

Curr Otorhinolaryngol Rep 2018 20;6(1):99-106. Epub 2018 Mar 20.

2Paediatric ENT, Royal Manchester Children's Hospital, Oxford Road, Manchester, M13 9WL UK.

Purpose Of Review: Our goal is to present the most up-to-date options in the surgical management of drooling in the paediatric population. While the clinical assessment of the drooling child and conservative management options are discussed, this review focuses on the most recent evidence for surgical interventions to treat drooling in children.

Recent Findings: In terms of advances in the management of drooling, further experience and outcomes with the use of botulinum toxin injections is discussed. Read More

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March 2018
3 Reads