1,685 results match your criteria Domestic animal endocrinology[Journal]


Responsiveness of swine divergently selected for feed efficiency to exogenous adrenocorticotropic hormone and glucose challenges.

Domest Anim Endocrinol 2018 Dec 28;68:32-38. Epub 2018 Dec 28.

Department of Animal Science, Iowa State University, Ames, IA 50011, USA.

Increasing the feed efficiency of lean tissue gains is an important goal for improving sustainable pork production and profitability for swine producers. To study feed efficiency, genetic selection based on residual feed intake (RFI) was used to create two divergent lines. Low-RFI pigs consume less feed for equal weight gain compared with their less-efficient, high-RFI counterparts. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.007DOI Listing
December 2018

Resveratrol addition to in vitro maturation and in vitro culture media enhances developmental competence of sheep embryos.

Domest Anim Endocrinol 2019 Jan 5;68:25-31. Epub 2019 Jan 5.

Department of Animal Science, IVF Laboratory, Faculty of Agricultural and Engineering Science, Razi University, Kermanshah, Iran.

The present study aimed to examine the effects of adding different concentrations of resveratrol during in vitro culture (IVC) alone and during both in vitro maturation (IVM) and IVC on ovine blastocyst yield and quality. Therefore, this study was conducted in two separate experiments. The first experiment was carried out to test the effect of different concentrations of resveratrol (0, 0. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.010DOI Listing
January 2019

The effect of estrone and estradiol on the expression of the orexin/hypocretin system in the porcine uterus during early pregnancy.

Domest Anim Endocrinol 2019 Jan 4;68:11-24. Epub 2019 Jan 4.

Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-719 Olsztyn, Poland. Electronic address:

Orexin A and B (OXA, OXB) are hypothalamic neuropeptides acting via two receptors, type 1 (OX1R) and 2 (OX2R). Orexins, also known as hypocretins, take part in a common endocrine system regulating metabolism and reproductive functions. Changes in the orexin system expression during the estrous cycle and pregnancy suggest dependence on the local hormonal milieu. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.008DOI Listing
January 2019

Supplementation with long-acting progesterone in early diestrus in beef cattle: II. Relationships between follicle growth dynamics and luteolysis.

Domest Anim Endocrinol 2018 Dec 19;68:1-10. Epub 2018 Dec 19.

Department of Animal Sciences, University of Florida, Gainesville, FL, USA. Electronic address:

The aims were to characterize follicular dynamics in response to supplemental progesterone (P4) and to investigate the relationships between follicular growth and onset of luteolysis in P4-treated cows, submitted or not to artificial insemination (AI). Nonsuckled beef cows detected in estrus were assigned to receive AI or to remain non-AI. Three days after ovulation (ie, D3), AI cows were injected with 150 mg of long-acting P4 (AI + injectable P4 formulation [iP4]; n = 22), and the non-AI cows were assigned to receive 150 mg iP4 (n = 19) or saline (control, n = 19). Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.004DOI Listing
December 2018
1 Read

In vitro survival, growth, and maturation of sheep oocytes from secondary follicles cultured in serum-free conditions: impact of a constant or a sequential medium containing recombinant human FSH.

Domest Anim Endocrinol 2018 Dec 18. Epub 2018 Dec 18.

Nucleus of Biotechnology Applied to Ovarian Follicle Development, Federal University of São Francisco Valley, Petrolina, PE 56300-990, Brazil. Electronic address:

This study evaluated the in vitro development and maturation of ovine oocytes from secondary follicles cultured in serum-free medium containing fixed or sequential concentrations of recombinant human FSH (rhFSH). Follicles were cultured in α-MEM alone or with constant (500, 750, or 1,000 ng/mL) or sequential concentrations of rhFSH (seq. 1: day 6 = 500; day 12 = 750; day 18 = 1,000 ng/mL and seq. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.003DOI Listing
December 2018

Supplementation with long-acting progesterone in early diestrus in beef cattle: I. effect of artificial insemination on onset of luteolysis.

Domest Anim Endocrinol 2018 Dec 18. Epub 2018 Dec 18.

Department of Animal Sciences, University of Florida, Gainesville, FL, USA. Electronic address:

Progesterone (P4) supplementation in early diestrus advances changes in the endometrial transcriptome, stimulating embryonic development. However, it also induces early onset of luteolysis. Occurrence of luteolysis before D16 postmating can be detrimental to fertility. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.002DOI Listing
December 2018

Assessment of ovulation synchronization protocols in goats and use of pregnancy specific protein B (PSPB) enzyme linked immunsorbent assay (ELISA) to determine kid number at birth.

Domest Anim Endocrinol 2018 Nov 30;67:54-62. Epub 2018 Nov 30.

Department of Animal Science, North Carolina State University, Raleigh, NC. Electronic address:

The efficacy of several protocols for ovulation synchronization and timed artificial insemination (TAI) in goats was examined. In addition, the relationship between levels of pregnancy specific protein B (PSPB) during gestation assessed with a commercially available ELISA and the number of offspring at birth was determined. In Experiment 1, 70 does were randomized into four treatments: (1) breed by estrus [BBE], (2) 6-d treatment with a new [C6N], (3) once-used [C61], or (4) twice-used Controled Internal Drug Release (CIDR) device [C62)]. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.11.002DOI Listing
November 2018

Expression and role of peroxisome proliferator-activated receptors in the porcine early placenta trophoblast.

Domest Anim Endocrinol 2018 Dec 11;67:42-53. Epub 2018 Dec 11.

Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland.

Peroxisome proliferator-activated receptors (PPARs) are members of a nuclear receptor family of ligand-dependent transcription factors. Three isoforms of PPAR named PPARα, PPARβ/δ, and PPARγ have been described, each encoded by a separate gene: PPARA, PPARD, and PPARG, respectively. In the present study, we examined the profiles of PPAR and retinoid X receptor (RXR; PPAR heterodimer partner) mRNA expression and PPAR DNA binding activity in porcine trophoblast tissue collected on days 15, 20, 25, and 30 of pregnancy and in day-20 embryos. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.001DOI Listing
December 2018

Correlation between estrogen plasma level and miRNAs in muscle of Piedmontese cattle.

Domest Anim Endocrinol 2018 Dec 19;67:37-41. Epub 2018 Dec 19.

Department of Veterinary Science, University of Torino, Largo Braccini 2, 10095 Grugliasco, TO, Italy.

A loss-of-function mutation of the myostatin gene has a very high prevalence in the Piedmontese cattle breed. The effect of such mutation is a double-muscle phenotype because of hypertrophy. However, differences in muscle mass development can still be detected in individuals of this breed. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.005DOI Listing
December 2018
1 Read

Effects of arachidonic acid and its major prostaglandin derivatives on bovine myoblast proliferation, differentiation, and fusion.

Authors:
X Leng H Jiang

Domest Anim Endocrinol 2018 Dec 19;67:28-36. Epub 2018 Dec 19.

Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

Many studies have shown positive effects of prostaglandins (PGs) on various steps of skeletal muscle formation such as myoblast proliferation and myotube hypertrophy. In animals, PGs are synthesized through the action of the rate-limiting enzymes cyclooxygenase (COX) -1 and COX-2 from arachidonic acid (AA), a conditionally essential fatty acid. As a step toward exploring the possibility of using dietary supplementation of AA to improve skeletal muscle growth in cattle, which are major meat-producing animals, we determined the effects of AA and its major PG derivatives PGE, PGF, and PGI on proliferation, differentiation, and fusion of primary bovine myoblasts in vitro. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.006DOI Listing
December 2018
5 Reads

Development of a sandwich ELISA for determining plasma prolactin concentration in domestic birds.

Domest Anim Endocrinol 2018 Nov 24;67:21-27. Epub 2018 Nov 24.

Jiangsu Key Laboratory for Food Quality and Safety, State Key Laboratory Cultivation Base of Ministry of Science and Technology, Institute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, Jiangsu, China. Electronic address:

The present study was conducted to establish a sandwich ELISA for the determination of prolactin (PRL) concentrations in the plasma of domestic fowls. The assay uses a recombinant goose PRL as the reference standard, expressed in a eukaryotic system, and as the antigen for raising a polyclonal antibody in rabbit. This rabbit anti-goose PRL polyclonal antibody was used for coating the wells of the ELISA plate, and its biotinylated form served as the detection antibody. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.11.001DOI Listing
November 2018
1 Read

Central injection of oxytocin reduces food intake and affects hypothalamic and adipose tissue gene expression in chickens.

Domest Anim Endocrinol 2018 Nov 3;67:11-20. Epub 2018 Nov 3.

Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

Oxytocin (OT) is a well-characterized neurotransmitter that participates in a wide range of physiological processes including the inhibition of food intake. The avian ortholog, mesotocin (MT), differs from OT by a single amino acid. Little is known regarding the function of OT in regulating energy balance in birds; thus, this study was designed to determine the effects of central OT injection on food intake and adipose tissue physiology in chicks. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.10.005DOI Listing
November 2018
1 Read

Impairment of the antifibrotic prostaglandin E pathway may influence neutrophil extracellular traps-induced fibrosis in the mare endometrium.

Domest Anim Endocrinol 2018 Nov 3;67:1-10. Epub 2018 Nov 3.

Department of Morphology and Function, CIISA- Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.

Prostaglandin E (PGE) has contradictory effects in many organs. It may have proinflammatory, anti-inflammatory, or anti-fibrotic roles, depending on the type of receptors to which it binds. By signaling through its receptors EP2 and EP4, PGE mediates anti-inflammatory and anti-fibrotic actions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183007
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http://dx.doi.org/10.1016/j.domaniend.2018.10.004DOI Listing
November 2018
23 Reads

Effect of stage of lactation and gestation on milking-induced hormone release in lactating dairy cows.

Domest Anim Endocrinol 2019 01 5;66:72-85. Epub 2018 Nov 5.

Sherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, Sherbrooke, Quebec J1M 0C8, Canada.

Three experiments were conducted to better understand why milking-induced prolactin (PRL) release decreases as lactation advances. Experiment 1 compared the effects of milking, 2-min manual stimulation of the mammary gland (without milking), or injection of 1 IU of oxytocin (without milking) on hormonal release in early lactation cows, late-lactation and nongestating cows, and late-lactation and gestating cows (n = 6 per physiological status). Blood samples were collected from 20 min before the start of the treatments to 60 min after. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.10.003DOI Listing
January 2019
2 Reads

Compound 48/80 reduces the crop-emptying rate, likely through a histamine-associated pathway in chicks.

Domest Anim Endocrinol 2019 01 23;66:57-63. Epub 2018 Oct 23.

Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

Infectious conditions are associated with reduced food passage through the digestive tract in both mammals and chicks; however, the precise mechanism mediating this response in chicks remains unclear. The purpose of the present study was to determine if mast cells, a blood cell type which plays an important role in the immune system, might affect food passage through the digestive tract in chicks. Specifically, we performed intraperitoneal (IP) injections of compound 48/80, an inducer of mast cell degranulation, and measured crop emptying. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183006
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http://dx.doi.org/10.1016/j.domaniend.2018.10.001DOI Listing
January 2019
9 Reads

Glucose, fructosamine, and insulin measurements in saliva of dogs: variations after an experimental glucose administration.

Domest Anim Endocrinol 2019 01 25;66:64-71. Epub 2018 Oct 25.

Interdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, Espinardo, Murcia, Spain.

The aim of this study was to evaluate if glucose, fructosamine, and insulin levels can be measured in saliva of dogs and assess the changes in these compounds after an experimental glucose administration. Automated spectrophotometric assays for glucose and fructosamine and an ELISA assay for insulin measurements were validated in saliva of dogs, by evaluating precision, accuracy, and limits of detection. In addition, an intravenous glucose bolus was administrated to 10 beagles and fasting serum and saliva samples were obtained immediately before and 5, 10, 20, 30, and 45 min after glucose infusion. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.10.002DOI Listing
January 2019
6 Reads

Bisphenol S, a Bisphenol A alternative, impairs swine ovarian and adipose cell functions.

Domest Anim Endocrinol 2019 01 23;66:48-56. Epub 2018 Aug 23.

Dipartimento di Scienze Medico-Veterinarie, Università di Parma, Via del Taglio 10, Parma 43126, Italy. Electronic address:

The high-volume-produced plastic monomer Bisphenol A (BPA) has been in the spotlight in the last years because of its endocrine disruptor (ED) behavior, leading to disclosure of the association between the widespread human and wildlife exposure to BPA and reproductive, metabolic, and developmental disorders and hormone-dependent cancer onset. These evidences caused restrictions and prohibitions of BPA industrial uses and prompted investigation of harmless alternative compounds. Above all, several countries have substituted the parental analogue with Bisphenol S (BPS) in baby care product manufacturing, even if its structural homology to BPA suggests similar ED properties not yet completely ruled out. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.08.001DOI Listing
January 2019
1 Read

Effect of artificial shade on saliva cortisol concentrations of heat-stressed dairy calves.

Domest Anim Endocrinol 2019 01 21;66:43-47. Epub 2018 Sep 21.

Department of Animal Hygiene, Herd Health and Veterinary Ethology, University of Veterinary Medicine, István utca 2, Budapest H-1078, Hungary.

Responses to heat stress have not been evaluated in dairy cattle by noninvasive techniques such as analysis of saliva cortisol concentrations. The aim of the present study was the assessment of saliva cortisol levels in Holstein bull calves with (n = 8) or without supplemental shade (n = 8) in response to acute heat stress. Measurements were carried out during a 5-d period [temperature, average/max (°C); day 1 (control, all calves shaded): 22. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.09.001DOI Listing
January 2019
2 Reads

In-depth characterization of the pituitary transcriptome in Simmental and Chinese native cattle.

Domest Anim Endocrinol 2019 01 26;66:35-42. Epub 2018 Sep 26.

Key Laboratory of Animal Genetics, Breeding and Molecular Design of Jiangsu province, Yangzhou University, Yangzhou 225002, China; Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou 225002, China. Electronic address:

The pituitary gland is a key endocrine organ responsible for growth and development. To get closer to understanding important molecular mechanisms at work in the bovine pituitary and identifying the core genes controlling growth, in the present study we have analyzed the transcriptome profiling of the pituitary glands of two cattle breeds (Wenshan and Simmental cattle) with extreme growth differences using high-throughput RNA sequencing. Our study revealed that the overall gene expression levels are quite similar between the two breeds. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183006
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http://dx.doi.org/10.1016/j.domaniend.2018.09.003DOI Listing
January 2019
11 Reads

Placental development during early pregnancy in sheep: nuclear estrogen and progesterone receptor mRNA expression in the utero-placental compartments.

Domest Anim Endocrinol 2019 01 26;66:27-34. Epub 2018 Sep 26.

Department of Animal Sciences, North Dakota State University, Fargo, ND 58108, USA.

Sex steroid hormones are major regulators of uterine and placental growth and functions, as well as many other biological processes. To examine the mRNA expression of nuclear estrogen (ESR1 and 2) and progesterone (PGRAB and B) receptors in different compartments of the uterus and placenta, tissues were collected in experiment 1 on days 16, 20, and 28 after natural mating (NAT) and on day 10 after estrus (nonpregnant controls [NP]); and in experiment 2 on day 22 of NAT, and pregnancies established after transfer of embryos generated through mating of FSH-treated ewes (NAT-ET), in vitro fertilization (IVF), or in vitro activation (parthenotes). In experiment 1, ESR1 expression in endometrial stroma (ES), endometrial glands (EGs), and myometrial blood vessels (MBVs), ESR2 in endometrial blood vessels (EBV), PGRAB in ES, and PGRB in ES, EG, and MBV was greater in pregnant than NP ewes depending on the day of pregnancy. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281792PMC
January 2019
1 Read
2.171 Impact Factor

Characterization of insulin and IGF-1 receptor binding in equine liver and lamellar tissue: implications for endocrinopathic laminitis.

Domest Anim Endocrinol 2019 01 7;66:21-26. Epub 2018 Jun 7.

Earth, Environmental and Biological Sciences School, Queensland University of Technology, Brisbane, Queensland, Australia. Electronic address:

Although it is well established that equine laminitis can be triggered by extreme hyperinsulinemia, the mechanism of insulin action is not known. High concentrations of insulin lead to separation of the weight-bearing apparatus from the hoof wall and are associated with an increased cycle of cell death and proliferation in the lamellae. Gene expression and immunohistochemistry studies have indicated that the lamellae are sparsely populated with insulin receptors, whereas IGF-1 receptors (IGF-1R) are abundant, suggesting that the action of insulin may be mediated by insulin binding to the IGF-1R. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.008DOI Listing
January 2019
2 Reads

Using domperidone to induce and sustain hyperprolactinemia in late-pregnant gilts.

Domest Anim Endocrinol 2019 01 17;66:14-20. Epub 2018 May 17.

Department of Animal Science, University of California Davis, Davis, CA, USA.

Prolactin controls mammary development as well as the lactogenic and galactopoietic processes in sows and increasing prolactin during gestation can augment milk yield. The dopamine receptor antagonist domperidone can increase circulating prolactin concentrations in pigs, but the ideal dose to achieve sustained hyperprolactinemia remains unknown. An experiment was performed to develop a protocol for using domperidone in studies of rapid and sustained hyperprolactinemia in late-pregnant gilts. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.004DOI Listing
January 2019
2 Reads

Oxytocin is involved in steroid hormone-stimulated bovine satellite cell proliferation and differentiation in vitro.

Domest Anim Endocrinol 2019 01 3;66:1-13. Epub 2018 Aug 3.

Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, USA. Electronic address:

Sex steroid hormones are used in the meat industry due to their ability to regulate muscle hypertrophy. However, the mechanisms underlying their action are not fully elucidated. Recent reports demonstrate that steroid hormones increase oxytocin (OXT) expression in skeletal muscle, indicating that OXT may play a role in satellite cell activity. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.07.003DOI Listing
January 2019
3 Reads

Gene expression profile associated with thymus regeneration in dexamethasone-treated beef cattle.

Domest Anim Endocrinol 2018 10 12;65:101-108. Epub 2018 Jul 12.

Dipartimento di Scienze Veterinarie, University of Turin, Largo Paolo Braccini 2, Grugliasco (TO) 10095, Italy.

Glucocorticoids (GCs) are illegally used as growth promoters in cattle, and the analytical methods officially applied most likely underestimate the precise frequency of the abuse. As a side effect, the administration of GCs causes fat infiltration, apoptosis, and atrophy of the thymus. However, gross and histological observations carried out previously showed that the thymus preserves an intrinsic ability to regenerate. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.07.002DOI Listing
October 2018
1 Read

Resistin regulates reproductive hormone secretion from the ovine adenohypophysis depending on season.

Domest Anim Endocrinol 2018 10 9;65:95-100. Epub 2018 Jul 9.

Department of Animal Biotechnology, Agricultural University of Krakow, Laboratory of Biotechnology and Genomics, Krakow, Poland. Electronic address:

Work in cattle and rodents has shown that resistin, in addition to its roles in insulin resistance and inflammation, is involved in the regulation of gonadal steroidogenesis. However, the role of resistin in the regulation of reproductive processes in other species, such as seasonally breeding sheep, is completely unknown. Herein, we tested the hypothesis that resistin can influence the secretion of anterior pituitary hormones and that its effect in ewes is dependent on the day length. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.07.001DOI Listing
October 2018
2 Reads

An FSH booster surge for resurgence of the preovulatory follicle in heifers.

Authors:
O J Ginther

Domest Anim Endocrinol 2018 10 28;65:90-94. Epub 2018 Jun 28.

Eutheria Foundation, Cross Plains, WI 53528, USA; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

Emergence of wave 1 during an interovulatory interval (IOI) in heifers is stimulated by FSH surge 1. A minor FSH surge with absence of a dominant follicle in the associated follicular wave occurs immediately before FSH surge 1. This minor surge is termed an FSH booster surge owing to its occurrence temporally during a resurgence of a preovulatory follicle that has been decreasing or lagging in growth rate for several days. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.06.002DOI Listing
October 2018
3 Reads

Safety and efficacy assessment of a GLP-1 mimetic: insulin glargine combination for treatment of feline diabetes mellitus.

Domest Anim Endocrinol 2018 10 9;65:80-89. Epub 2018 May 9.

Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Dr, Saskatoon, Canada. Electronic address:

A commonly used therapeutic strategy for type 2 diabetes mellitus (DM) in humans involves the use of synthetic incretin hormone-based therapies including exenatide, a glucagon-like pepetide-1 hormone agonist. Glucagon-like pepetide-1 agonists can be used alone or as an ancillary therapy with other agents, including insulin and oral antihyperglycemics. Little is known about the role of these therapies for DM in cats. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.003DOI Listing
October 2018
2 Reads

Influences of maternal nutrient restriction and arginine supplementation on visceral metabolism and hypothalamic circuitry of offspring.

Domest Anim Endocrinol 2018 10 20;65:71-79. Epub 2018 Jun 20.

Department of Animal Sciences, North Dakota State University, Hultz Hall 166, Dept. 7630, PO Box 6050, Fargo 58108, USA. Electronic address:

Maternal nutrient restriction during gestation can exert long-term negative effects on offspring health and performance. Arginine supplementation may rescue some of the negative effects elicited by maternal nutrient restriction. We tested the hypothesis that maternal arginine supplementation during gestation would rescue deleterious effects of nutrient restriction on in vitro O consumption in the liver and jejunum and hypothalamic protein expression of proopiomelanocortin (POMC), neuropeptide Y (NPY), agouti-related peptide (AgRP), and neuronal nitric oxide synthase (nNOS), and the colocalization of nNOS and active phosphor-signal transducer and activator of transcription 3 (pSTAT3) in female offspring. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.06.001DOI Listing
October 2018
2 Reads

Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs.

Domest Anim Endocrinol 2018 10 4;65:67-70. Epub 2018 Jun 4.

South Australian Research and Development Institute, Urrbrae, South Australia, SA 5371, Australia.

Environment enrichment is a rising topic for animal welfare but measures to identify effective enrichment interventions are lacking. In humans and rodent species, environmental enrichment increases brain-derived neurotrophic factor (BDNF), the most abundant neurotrophin in the brain. Higher BDNF concentration is ultimately linked to higher stress resilience, and BDNF in the hippocampus enhances learning and memory. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.007DOI Listing
October 2018
1 Read

Tissue-specific expression and circulating concentrations of nesfatin-1 in domestic animals.

Domest Anim Endocrinol 2018 10 9;65:56-66. Epub 2018 May 9.

Department of Veterinary Biomedical Sciences, Laboratory of Integrative Neuroendocrinology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada. Electronic address:

Nesfatin-1 is a naturally occurring 82-amino acid protein encoded in the precursor nucleobindin-2 (NUCB2) and has been implicated in multiple physiological functions, including food intake and blood glucose regulation. This study aimed to characterize nesfatin-1 in domestic species, especially cats (Felis catus), dogs (Canis lupus familiaris), and pigs (Sus scrofa). Our in silico analysis demonstrated that the NUCB2/nesfatin-1 amino acid sequence, especially the bioactive core region of the peptide, is very highly conserved (more than 90% identity) in domestic animals. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.006DOI Listing
October 2018
1 Read

Excess deposition of collagen in mammary glands of tamoxifen-treated Holstein heifers is associated with impaired mammary growth.

Domest Anim Endocrinol 2018 10 18;65:49-55. Epub 2018 May 18.

Department of Dairy Science, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

It is established that the ovary and estrogen are essential to bovine mammary development with the onset of puberty. Recent studies have shown that ovariectomy in the very early prepubertal period, well before onset of puberty, also dramatically impairs mammary growth. Similarly, prepubertal heifers treated with the antiestrogen tamoxifen (TAM) also exhibit markedly impaired mammary growth in correspondence with reduced estrogen receptor α (ESR1) expression. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.006DOI Listing
October 2018
1 Read

Supplementation with CTGF, SDF1, NGF, and HGF promotes ovine in vitro oocyte maturation and early embryo development.

Domest Anim Endocrinol 2018 10 17;65:38-48. Epub 2018 May 17.

State Key Laboratory of Reproductive Regulation & Breeding of Grassland Livestock, The Research Center for Laboratory Animal Science, College of Life Science, Inner Mongolia University, Hohhot, Inner Mongolia, People's Republic of China. Electronic address:

The strategies for improving the in vitro maturation (IVM) of domestic animal oocytes focus on promoting nuclear and cytoplasmic maturation. The identification of paracrine factors and their supplementation in the culture medium represent effective approaches for oocyte maturation and embryo development. This study investigated the effects of paracrine factor supplementation including connective tissue growth factor (CTGF), nerve growth factor (NGF), hepatocyte growth factor (HGF), and stromal derived factor 1 (SDF1) on ovine oocytes and early parthenogenetic embryos using an in vitro culture system. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.003DOI Listing
October 2018
1 Read

Influence of postweaning feeding management of beef heifers on performance and physiological profiles through rearing and first lactation.

Domest Anim Endocrinol 2018 10 9;65:24-37. Epub 2018 May 9.

Centro de Investigación y Tecnología Agroalimentaria (CITA) de Aragón, Instituto Agroalimentario de Aragón (IA2, CITA-Universidad de Zaragoza), Avenida, Montañana, 930, 50059 Zaragoza, Spain.

The aim of this study was to examine the effects of 2 postweaning feeding management approaches (FEED: 0.8 [HIGH] vs 0.6 [MOD] kg/d target ADG) on the performance of heifers of 2 beef breeds (BREED: Parda de Montaña [PA] vs Pirenaica) calving at 2 yr. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.001DOI Listing
October 2018
6 Reads

MiRNA-seq reveals that miR-124-3p inhibits adipogenic differentiation of the stromal vascular fraction in sheep via targeting C/EBPα.

Domest Anim Endocrinol 2018 10 9;65:17-23. Epub 2018 May 9.

College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China. Electronic address:

MicroRNAs (miRNAs) are small noncoding 20-25 nt RNA molecules that regulate gene expression by posttranscriptional repression of messenger RNA. There have been few investigations on the profiles and functions of miRNAs in ovine subcutaneous fat; their roles in the metabolism and deposition of subcutaneous fat also remain unclear. In this study, small RNA libraries were constructed for 2 important Chinese local sheep breeds, Small-tailed Han Sheep, and Shanxi Meat Sheep Dam Line, and used for high-throughput sequencing. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.002DOI Listing
October 2018
2 Reads

Effects of chronic dexamethasone exposure on bile acid metabolism and cecal epithelia function in goats.

Domest Anim Endocrinol 2018 10 17;65:9-16. Epub 2018 May 17.

Key Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing, P.R. China.

Bile acids (BAs) are synthesized in the liver via the oxidation of cholesterol and further metabolized by microbiota in the gut, where they simultaneously impact gut function. In the present study, 10 goats were randomly divided into 2 groups; 1 group was injected with dexamethasone (Dex; 0.2 mg/kg), and the other group was injected with saline as the control (Con) for 21 d. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.05.005DOI Listing
October 2018
2 Reads

Congenital dyshormonogenic hypothyroidism with goiter caused by a sodium/iodide symporter (SLC5A5) mutation in a family of Shih-Tzu dogs.

Domest Anim Endocrinol 2018 10 24;65:1-8. Epub 2018 Apr 24.

Laboratory of Comparative Medical Genetics and Department of Microbiology and Molecular Genetics, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.

An iodide transport defect (ITD) in the thyroid gland was determined to cause congenital dyshormonogenic hypothyroidism with goiter (CDHG) in 2 members of a family of Shih-Tzu dogs. Strikingly, both dogs were also diagnosed with dilated cardiomyopathy at 24 and 1.5 mo of age. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.005DOI Listing
October 2018
19 Reads

Lactation-related changes in tissue expression of PEDF in dairy cows.

Domest Anim Endocrinol 2018 07 17;64:93-101. Epub 2018 Apr 17.

Institute of Animal Science, Physiology & Hygiene Unit, University of Bonn, Bonn 53111, Germany. Electronic address:

Pigment epithelium-derived factor (PEDF) is evolving as metabolic regulatory protein. Albeit mostly considered in only pathological conditions related to excess energy intake resulting in obesity and insulin resistance, PEDF is likely to be involved in other physiological processes such as the homeorhetic adaptation of metabolism to lactation. We aimed to characterize the expression of PEDF and its association to the concomitant mobilization of body reserves during lactation in nonobese subjects. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.004DOI Listing
July 2018
6 Reads

Prolonged exposure of dietary phytoestrogens on semen characteristics and reproductive performance of rabbit bucks.

Domest Anim Endocrinol 2018 Jul 28;64:84-92. Epub 2018 Mar 28.

Department of Animal and Fish Production, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria, Egypt.

The effects of inclusion of different sources of dietary phytoestrogens on antioxidant capacity, hormonal balance, libido, semen quality, and fertility of rabbit bucks were studied. Twenty-one, adult, fertile, V-line bucks were randomly allocated into 3 homogenous groups (n = 7/treatment) and received control diet (phytoestrogens-free diet, CON) or soybean meal isoflavones-containing diet (SMI) or linseed meal lignans-containing diet (LML) for 12 wk. The diets were formulated to be isocaloric and isonitrogenous. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183001
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http://dx.doi.org/10.1016/j.domaniend.2018.03.003DOI Listing
July 2018
8 Reads

Influence of brain plasmalogen changes on gonadotropin secretion from the cultured bovine anterior pituitary cells.

Domest Anim Endocrinol 2018 07 10;64:77-83. Epub 2018 Apr 10.

Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi-shi, Yamaguchi-ken, 1677-1, Japan. Electronic address:

We recently discovered that the orphan G-protein-coupled receptor (GPR) 61 colocalized with GnRH receptors (GnRHRs) on the surface of most of bovine gonadotrophs. A recent study suggested that ethanolamine plasmalogen (PI) is a ligand for GPR61 in mouse neuroblastoma. Therefore, this study evaluated the hypothesis that PI alters LH and FSH secretion from cultured bovine anterior pituitary (AP) cells. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.002DOI Listing
July 2018
5 Reads

Dietary nitrogen and calcium modulate CYP27B1 expression in young goats.

Domest Anim Endocrinol 2018 07 3;64:70-76. Epub 2018 Apr 3.

Department of Physiology, University of Veterinary Medicine Hannover, Bischofsholer Damm 15/102, D-30173 Hannover, Germany. Electronic address:

In livestock, feeding a reduced nitrogen (N) diet is favored for economic and ecological reasons. Ruminants cope more easily with a reduced N diet than monogastric species. However, changes in mineral homeostasis such as a reduction in 1,25-dihydroxyvitamin D (1,25-(OH)D) concentrations, calcium (Ca), and IGF1 levels were observed in goats kept on a reduced N diet. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.03.005DOI Listing
July 2018
2 Reads

Impact of an auditory stimulus on baseline cortisol concentrations in clinically normal dogs.

Domest Anim Endocrinol 2018 07 19;64:66-69. Epub 2018 Mar 19.

Veterinary Medical Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 408 Raymond Stotzer Pkwy, College Station, TX 77845, USA. Electronic address:

Baseline cortisol concentrations are routinely used to screen dogs for hypoadrenocorticism (HOC); this diagnosis must then be confirmed with an ACTH stimulation test. A baseline cortisol concentration less than 55 nmol/L (2 μg/dL) is highly sensitive for HOC but lacks specificity, with a false positive rate >20%. Many dogs with nonadrenal disease are therefore subjected to unnecessary additional testing. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183001
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http://dx.doi.org/10.1016/j.domaniend.2018.03.002DOI Listing
July 2018
3 Reads

Effect of l-tryptophan and its metabolites on food passage from the crop in chicks.

Domest Anim Endocrinol 2018 07 16;64:59-65. Epub 2018 Mar 16.

Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

l-tryptophan (l-Trp), an essential amino acid, is well known as a precursor of 5-hydroxytryptamine (5-HT) and melatonin. In mammals, l-Trp itself has been reported to suppress gastric emptying in mammals. In addition, 5-HT and melatonin are found in the gastrointestinal tract and affect food passage from the digestive tract in mammals. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.03.001DOI Listing
July 2018
20 Reads

Evaluation of glucose and insulin response to haylage diets with different content of nonstructural carbohydrates in 2 breeds of horses.

Domest Anim Endocrinol 2018 07 9;64:49-58. Epub 2018 Apr 9.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Box 7054, SE-750 07 Uppsala, Sweden.

Information about the effect of nonstructural carbohydrates (NSCs) in forage on the postprandial glucose and insulin response in horses is scarce. This is of interest as postprandial hyperinsulinemia in horses is a risk factor for laminitis. In addition, insulin sensitivity (IS) differs between breeds. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.03.006DOI Listing
July 2018
1 Read

Orexin A in swine corpus luteum.

Domest Anim Endocrinol 2018 07 9;64:38-48. Epub 2018 Apr 9.

Dipartimento di Scienze Medico-Veterinarie, Università di Parma, Via del Taglio 10, 43126, Parma, Italy.

Orexin A (OXA) is a hypothalamic neuropeptide which acts on 2 known G-protein-coupled receptors. It has been demonstrated that OXA is a central molecular link between food intake and reproduction. More recently, its peripheral role has been investigated, and we demonstrated its involvement in regulating ovarian follicle function. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.04.001DOI Listing
July 2018
3 Reads

Association of body weight gain with muscle, fat, and liver expression levels of growth hormone receptor, insulin-like growth factor I, and beta-adrenergic receptor mRNAs in steers.

Domest Anim Endocrinol 2018 07 9;64:31-37. Epub 2018 Apr 9.

Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, USA. Electronic address:

The physiological basis of feed efficiency is unclear. Administration of GH or beta-adrenergic agonists improves feed efficiency in various animals. The objective of this study was to test the hypothesis that more efficient cattle have greater expression of GH receptor (GHR) or beta-adrenergic receptor (ADRB) mRNA in skeletal muscle, fat, and liver, the major target tissues of GH and beta-adrenergic agonists. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.03.008DOI Listing
July 2018
1 Read

Pharmacodynamics and pharmacokinetics of insulin detemir and insulin glargine 300 U/mL in healthy dogs.

Domest Anim Endocrinol 2018 Jul 10;64:17-30. Epub 2018 Apr 10.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA. Electronic address:

Insulin glargine 300 U/mL and insulin detemir are synthetic long-acting insulin analogs associated with minimal day-to-day variability or episodes of hypoglycemia in people. Here, 8 healthy purpose-bred dogs each received 2.4 nmol/kg subcutaneous injections of insulin detemir (0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07397240183001
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http://dx.doi.org/10.1016/j.domaniend.2018.03.007DOI Listing
July 2018
4 Reads

The expression of autophagy-related proteins within the corpus luteum lifespan in pigs.

Domest Anim Endocrinol 2018 07 3;64:9-16. Epub 2018 Apr 3.

Department of Animal Physiology and Endocrinology, University of Agriculture in Krakow, Al. Mickiewicza 24/28, 30-059 Krakow, Poland.

Autophagy is a cellular process that involves the degradation of intracellular components. Recent studies suggested a role for autophagy in corpus luteum (CL) regression; however, a complete understanding of its contribution to CL function remains unclear. The present research using porcine CLs obtained from gilts at the early (CL1, n = 5), middle (CL2, n = 5), and late (CL3, n = 5) luteal phase of the estrous cycle aimed to assess the incidence of autophagy during CL development. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.03.004DOI Listing
July 2018
1 Read

Hair cortisol and progesterone detection in dairy cattle: interrelation with physiological status and milk production.

Domest Anim Endocrinol 2018 Jul 19;64:1-8. Epub 2018 Feb 19.

Department of Animal Health and Anatomy, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. Electronic address:

Hair cortisol concentrations (HCCs) and hair progesterone concentrations (HPCs) allow monitoring long-term retrospective steroid levels. However, there are still gaps in the knowledge of the mechanisms of steroid deposition in hair and its potential application in dairy cattle research. This study aimed to evaluate the potential uses of hair steroid determinations by studying the interrelations between HCC, HPC, physiological data from cows, and their milk production and quality. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.02.001DOI Listing
July 2018
2 Reads

Expression of membrane progestin receptors (mPRs) in the bovine corpus luteum during the estrous cycle and first trimester of pregnancy.

Domest Anim Endocrinol 2018 04 11;63:69-76. Epub 2018 Jan 11.

Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland.

Progesterone (P4) affects luteal cell function through nuclear P4 receptors and via nongenomic mechanisms, presumably involving membrane P4 receptors. There are 2 types of these receptors: progesterone receptor membrane component (PGRMC) and membrane progestin receptor (mPR), including mPR alpha (mPRα), beta (mPRβ), and gamma (mPRγ), which belong to the progestin and adipoQ receptor family (PAQR 7, 8, and 5, respectively). The aim of this study was to evaluate mRNA expression, protein expression, and localization of mPRα, mPRβ, and mPRγ in the bovine corpus luteum (CL) on days 2-5, 6-10, 11-16, and 17-20 of the estrous cycle as well as on weeks 3-5, 6-8, and 9-12 of pregnancy (n = 5/each period). Read More

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http://dx.doi.org/10.1016/j.domaniend.2017.12.004DOI Listing
April 2018
3 Reads

Orexin A but not orexin B regulates lipid metabolism and leptin secretion in isolated porcine adipocytes.

Domest Anim Endocrinol 2018 04 4;63:59-68. Epub 2018 Jan 4.

Department of Animal Physiology and Biochemistry, Poznan University of Life Sciences, Wołynska Street 35, 60-637 Poznan, Poland.

It is well known that orexins are involved in the metabolism and endocrine function of rodent adipocytes, but there are no data on other animal species, including pigs. Therefore, in this study, we tested the hypothesis that orexin A (OxA) and orexin B (OxB) modulate the metabolism and endocrine functions of isolated porcine adipocytes and adipose tissue explants. Moreover, we characterized the possible mechanism of OxA action in porcine adipocytes. Read More

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http://dx.doi.org/10.1016/j.domaniend.2017.12.003DOI Listing
April 2018
2 Reads