664 results match your criteria Dizziness Vertigo and Imbalance

Symptoms and clinical features in patients affected by endolymphatic sac tumor: a systematic review and meta-analysis.

Eur Arch Otorhinolaryngol 2022 Jun 15. Epub 2022 Jun 15.

Department of Clinical and Molecular Sciences, ENT Unit, Polytechnic University of Marche, Ancona, Italy.

Purpose: Most ELST data in the literature are case studies or limited to small cohorts (< 16 patients). We evaluated the main clinical signs observed at endolymphatic sac tumor (ELST) diagnosis in patients with or without Von Hippel-Lindau disease.

Methods: We conducted a comprehensive literature search in PubMed, Scopus, and Web of Science. Read More

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Characterization of Thyroid Hormones Antivertigo Effects in a Rat Model of Excitotoxically-Induced Vestibulopathy.

Front Neurol 2022 25;13:877319. Epub 2022 May 25.

Aix Marseille Université-CNRS, Laboratoire de Neurosciences Cognitives, LNC UMR 7291, Marseille, France.

Impaired vestibular function induces disabling symptoms such as postural imbalance, impaired locomotion, vestibulo-ocular reflex alteration, impaired cognitive functions such as spatial disorientation, and vegetative deficits. These symptoms show up in sudden attacks in patients with Ménière or neuritis and may lead to emergency hospitalizations. To date, however, there is no curative solution to these pathologies and the effectiveness of treatments used to reduce symptoms in the management of patients is discussed. Read More

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Clinical and cVEMP Evaluation Predict Short-Term Residual Dizziness After Successful Repositioning in Benign Paroxysmal Positional Vertigo.

Front Med (Lausanne) 2022 24;9:881307. Epub 2022 May 24.

Department of Neurology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Objective: Residual dizziness (RD) is a frequent symptom with unknown pathogenesis, often complained about by the patients with benign paroxysmal positional vertigo (BPPV), even after a successful canalith repositioning procedure (CRP). This study aims to quantitatively evaluate the short-term RD severity and its risk factors in patients with BPPV after successful CRPs.

Methods: In total two hundred and twenty patients with BPPV after successful CRPs (W0) were prospectively followed up for 1 week (W1). Read More

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Significance of Vertigo, Imbalance, and Other Minor Symptoms in Hyperacute Treatment of Posterior Circulation Stroke.

Front Neurol 2022 16;13:845707. Epub 2022 May 16.

Department of Neurology, Ajou University Medical Center, Ajou University School of Medicine, Suwon, South Korea.

Background: This study aimed to determine the clinical significance of acute vestibular syndrome (AVS)/acute imbalance syndrome (AIS) in posterior circulation stroke (PCS) and how it should be addressed in the thrombolysis code.

Methods: Our institution has recently changed its thrombolysis code from one that is generous to AVS/AIS to one that is exclusive. The subjects in this study were patients with PCS who presented before this transition (May 2016 to April 2018, period 1) and those who presented after (January 2019 to December 2020, period 2) with an onset-to-door time of 4. Read More

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Effects of Low-Intensity Vestibular Noise Stimulation on Postural Instability in Patients with Parkinson's Disease.

J Parkinsons Dis 2022 Apr 28. Epub 2022 Apr 28.

German Center for Vertigo and Balance Disorders (DSGZ), Ludwig-Maximilians-University of Munich, Munich, Germany.

Background: Postural instability is a major disabling factor in patients with advanced Parkinson's disease (PD) and often resistant to treatment. Previous studies indicated that imbalance in PD may be reduced by low-intensity noisy galvanic vestibular stimulation (nGVS).

Objective: To investigate the potential mode of action of this therapeutic effect. Read More

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Evaluation of VHIT values compared to other diagnostic tests that can be performed in a patient with dizziness and balance disorders.

Otolaryngol Pol 2021 Dec;76(2):24-33

Department of Otolaryngology, Laryngological Oncology, Audiology and Phoniatrics Second Department of Otolaryngology, Medical University of Lodz, Poland.

<b>Introduction:</b> Dizziness and imbalance occur in 20-30% of adults, which is a significant health problem.</br></br> <b>Aim:</b> The aim of the study was to assess the value of the VHIT test against the background of other diagnostic tests, including videonystagmographic (VNG) examination, Dix-Hallpike maneuver, VHIT test, posturographic examination, which are possible to perform in a patient with dizziness. </br></br> <b>Material and methods:</b> The study was performed in 200 patients aged 18-78 years, who were divided into two groups: I study - 100 patients with mixed dizziness, aged 18-78 years, II (reference group) - 100 healthy patients (students of the Faculty of Mili-tary and Medical University of Lodz and patients of the Clinic, without anamnesis of body imbalances (preventive examination), aged 20-60 years. Read More

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December 2021

Vestibular Migraine: Clinical Aspects and Pathophysiology.

Otolaryngol Clin North Am 2022 Jun 25;55(3):531-547. Epub 2022 Apr 25.

Department of Otolaryngology-Head & Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD 21287, USA. Electronic address:

VM is a common yet debilitating migraine variant that has taken many monikers in the past. As a relatively new diagnostic entity, public and provider awareness of this disorder can be improved. Symptoms include vertigo episodes in addition to photophobia, phonophobia, nausea, and headache. Read More

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Toward a Digital Health Intervention for Vestibular Rehabilitation: Usability and Subjective Outcomes of a Novel Platform.

Front Neurol 2022 29;13:836796. Epub 2022 Mar 29.

Academic Unit of Neurology, School of Medicine, Trinity College Dublin, Dublin, Ireland.

Digital technologies are increasingly available and are reducing in cost. There is an opportunity to move to a digital health approach in vestibular rehabilitation (VR), but there is a paucity of suitable systems available and a consequent lack of evidence to support their use. This study aimed to investigate a novel digital platform developed specifically for VR (comprising clinician software, a wearable sensor, and a patient-facing app). Read More

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Downbeat nystagmus becomes attenuated during walking compared to standing.

J Neurol 2022 Apr 12. Epub 2022 Apr 12.

German Center for Vertigo and Balance Disorders, University Hospital, LMU, Munich, Germany.

Downbeat nystagmus (DBN) is a common form of acquired fixation nystagmus related to vestibulo-cerebellar impairments and associated with impaired vision and postural imbalance. DBN intensity becomes modulated by various factors such as gaze direction, head position, daytime, and resting conditions. Further evidence suggests that locomotion attenuates postural symptoms in DBN. Read More

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The perception of family members regarding patient's vertigo and imbalance.

Acta Otorrinolaringol Esp (Engl Ed) 2022 Mar-Apr;73(2):89-95

Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction And Objectives: Family members play a major role in the assessment and final result of the treatments of patients. The goal of the present study was to evaluate how much the perception of patients' family members could be trusted regarding the vertigo and imbalance which they experienced.

Materials And Methods: A cross-sectional study was conducted on 110 patients and their family members who were referred to the Central Vestibular Clinic in Mashhad from April 2018 to September 2019. Read More

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Nystagmus only with fixation in the light: a rare central sign due to cerebellar malfunction.

J Neurol 2022 Jul 9;269(7):3879-3890. Epub 2022 Apr 9.

Department of Neurology, Dizziness Center, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, South Korea.

Fixation nystagmus refers to the nystagmus that appears or markedly increases with fixation. While relatively common in infantile (congenital) nystagmus, acquired fixation nystagmus is unusual and has been ascribed to lesions involving the cerebellar nuclei or the fibers projecting from the cerebellum to the brainstem. We aimed to report the clinical features of patients with acquired fixation nystagmus and discuss possible mechanisms using a model simulation and diagnostic significance. Read More

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Development and Content Validity of the Bilateral Vestibulopathy Questionnaire.

Front Neurol 2022 17;13:852048. Epub 2022 Mar 17.

Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, Netherlands.

Background: To date, the burden and severity of the full spectrum of bilateral vestibulopathy (BVP) symptoms has not yet been measured in a standardized manner. Since therapeutic interventions aiming to improve BVP symptoms are emerging, the need for a new standardized assessment tool that encompasses the specific aspects of BVP arises. Therefore, the aim of this study was to develop a multi-item Patient Reported Outcome Measure (PROM) that captures the clinically important symptoms of BVP and assesses its impact on daily life. Read More

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Vascular vertigo and dizziness: Diagnostic criteria.

J Vestib Res 2022 ;32(3):205-222

Department of Neurology and German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Germany.

This paper presents diagnostic criteria for vascular vertigo and dizziness as formulated by the Committee for the Classification of Vestibular Disorders of the Bárány Society. The classification includes vertigo/dizziness due to stroke or transient ischemic attack as well as isolated labyrinthine infarction/hemorrhage, and vertebral artery compression syndrome. Vertigo and dizziness are among the most common symptoms of posterior circulation strokes. Read More

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Factors determining the response to treatment in patients with vestibular migraine.

Neurol Res 2022 Mar 29:1-8. Epub 2022 Mar 29.

Department of Neurology, University of Health Sciences Izmir Tepecik Education and Research Hospital, Izmir, Turkey.

Purpose: To find out clinical features associated with poor response to treatment in vestibular migraine (VM).

Methods: VM patients treated with drugs recommended in migraine prophylaxis were included in this multicenter study. Migraine features including type, age of onset of headache and vertigo attacks, attack frequency, intensity, associated symptoms, triggering factors, presence of interictal dizziness/imbalance, anxiety, depression, history of motion sickness, and family history of migraine were noted. Read More

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In vivo neuroplasticity in vestibular animal models.

Mol Cell Neurosci 2022 05 22;120:103721. Epub 2022 Mar 22.

Department of Neurology, University Hospital, LMU Munich, Germany; German Center for Vertigo and Balance Disorders, DSGZ, LMU Munich, Germany; Munich Cluster of Systems Neurology, SyNergy, Munich, Germany.

An acute unilateral vestibulopathy leads to symptoms of vestibular tone imbalance, which gradually decrease over days to weeks due to central vestibular compensation. Animal models of acute peripheral vestibular lesions are optimally suited to investigate the mechanisms underlying this lesion-induced adaptive neuroplasticity. Previous studies applied ex vivo histochemical techniques or local in vivo electrophysiological recordings mostly in the vestibular nucleus complex to delineate the mechanisms involved. Read More

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Identification of Stroke and TIA in Patients With Acute Dizziness, Vertigo or Imbalance in Emergency Departments of Primary Care Hospitals: Early Experiences With a Network-Based Telemedical Approach.

Front Neurol 2022 2;13:766685. Epub 2022 Mar 2.

Department of Neurology, TEMPiS Telestroke Center, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Munich, Germany.

Background: Acute dizziness, vertigo, and imbalance are frequent and difficult to interpret symptoms in the emergency department (ED). Primary care hospitals often lack the expertise to identify stroke or TIA as underlying causes. A telemedical approach based on telestroke networks may offer adequate diagnostics and treatment. Read More

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Agreement Between Caloric and Horizontal Video Head Impulse Testing in School-Aged Children Presenting With Dizziness.

Am J Audiol 2022 Jun 14;31(2):299-304. Epub 2022 Mar 14.

Division of Vestibular Sciences, Vanderbilt University Medical Center, Nashville, TN.

Objective: The purpose of this investigation was to determine the relationship between the horizontal semicircular canal video head impulse test (hvHIT) and the caloric test in a sample of school-age children evaluated due to complaints of dizziness or imbalance. In adults, these two tests provide different but complementary information regarding vestibular function and/or pathology. However, the most common causes of vestibular loss in children are different than those in adults, and it is not clear how these two tests of horizontal semicircular canal function are related in a pediatric population. Read More

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A Dynamic Nomogram to Predict the Risk of Stroke in Emergency Department Patients With Acute Dizziness.

Ying Bi Fei Cao

Front Neurol 2022 18;13:839042. Epub 2022 Feb 18.

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: To develop a risk prediction tool for acute ischemic stroke (AIS) for patients presenting to the emergency department (ED) with acute dizziness/vertigo or imbalance.

Method: A prospective, multicenter cohort study was designed, and adult patients presenting with dizziness/vertigo or imbalance within 14 days were consecutively enrolled from the EDs of 4 tertiary hospitals between August 10, 2020, and June 10, 2021. Stroke was diagnosed by CT or MRI performed within 14 days of symptom onset. Read More

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February 2022

Feasibility of Telemedical HINTS (Head Impulse-Nystagmus-Test of Skew) Evaluation in Patients With Acute Dizziness or Vertigo in the Emergency Department of Primary Care Hospitals.

Front Neurol 2021 11;12:768460. Epub 2022 Feb 11.

Department of Neurology, TEMPiS Telestroke Center, Academic Teaching Hospital of the Ludwig-Maximilians-University, München Klinik, Munich, Germany.

Background: Acute dizziness, vertigo and imbalance are common symptoms in emergency departments. Stroke needs to be distinguished from vestibular diseases. A battery of three clinical bedside tests (HINTS: Head Impulse Test, Nystagmus, Test of Skew) has been shown to detect stroke as underlying cause with high reliability, but implementation is challenging in primary care hospitals. Read More

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February 2022

Prevalence and distribution of musculoskeletal pain in patients with dizziness-A systematic review.

Physiother Res Int 2022 Apr 21;27(2):e1941. Epub 2022 Feb 21.

Western Norway University of Applied Sciences, Bergen, Norway.

Background And Purpose: Musculoskeletal disorders are among the leading causes of disability globally, but their role in patients with dizziness and imbalance is not well understood or explored. Such knowledge may be important as musculoskeletal pain and dizziness can mutually influence each other, leading to a complex condition requiring more comprehensive approaches to promote successful recovery. We conducted a systematic review to examine the extent and characteristic of reported musculoskeletal pain in patients with dizziness. Read More

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Visual fixations and visually induced dizziness: An exploratory study.

Gait Posture 2022 03 9;93:153-159. Epub 2022 Feb 9.

Rehabilitation Innovation Centre, Health and Rehabilitation Research Institute, Auckland University of Technology, Auckland 0627, New Zealand. Electronic address:

Background: Visually induced dizziness can develop as a sequala of a vestibular disorder and is characterized by symptoms of nausea, dizziness, and imbalance in rich visual environments such as supermarkets and shopping malls. To date the mechanisms underlying visually induced dizziness are poorly understood.

Research Question: What are the characteristics of visual fixations and postural sway in adults with visually induced dizziness compared to healthy adults when exposed to increasingly complex visual environments?

Methods: We recruited 20 adults with visually induced dizziness and 20 healthy adults to this cross-sectional exploratory study. Read More

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"Positional" upbeat nystagmus in medullary lesions.

Acta Neurol Belg 2022 06 3;122(3):837-839. Epub 2022 Feb 3.

Department of Clinical Laboratory, Yokohama Brain and Spine Center, Yokohama, Japan.

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A Portrait of Menière's Disease Using Contemporary Hearing and Balance Tests.

Otol Neurotol 2022 04;43(4):e489-e496

Central Clinical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.

Objective: Menière's disease (MD) is characterized by recurrent vertigo and fluctuating aural symptoms. Diagnosis is straightforward in typical presentations, but a proportion of patients present with atypical symptoms. Our aim is to profile the array of symptoms patients may initially present with and to analyze the vestibular and audiological test results of patients with a diagnosis of MD. Read More

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In Search of a Neurotologic Profile in COVID-19 - A Study in Health Care Workers.

Cureus 2022 Jan 7;14(1):e21015. Epub 2022 Jan 7.

Statistics, Universidad Autonoma de Sinaloa, Culiacan, MEX.

Introduction COVID-19 is an emerging disease and the neurotologic symptoms are still not well understood. Furthermore, the development of a neurotological profile and its associated factors can help the clinician in the diagnosis and treatment of this disease. The objective is to determine the neurotologic manifestations experienced by COVID-19 positive health care workers and their associated factors. Read More

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January 2022

Vestibular function testing in the 21st century: video head impulse test, vestibular evoked myogenic potential, video nystagmography; which tests will provide answers?

Curr Opin Neurol 2022 02;35(1):64-74

Central Clinical School, Faculty of Medicine and Health, University of Sydney.

Purpose Of Review: To most neurologists, assessing the patient with vertigo is an unpleasant and worrisome task. A structured history and focused examination can be complemented by carefully selected laboratory tests, to reach an early and accurate diagnosis. We provide evidence-based recommendations for vestibular test selection. Read More

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February 2022

Vestibular Rehabilitation for Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From the Academy of Neurologic Physical Therapy of the American Physical Therapy Association.

J Neurol Phys Ther 2022 Apr;46(2):118-177

Hearing and Balance Research Program, James H. Quillen VAMC, Mountain Home, and Physical Therapy Program, Department of Rehabilitative Sciences, East Tennessee State University, Johnson City, Tennessee (C.D.H.); Department of Physical Medicine and Rehabilitation, School of Medicine (Emerita), Emory University, Atlanta, Georgia (S.J.H.); Department of Physical Therapy, School of Health and Rehabilitation Science, University of Pittsburgh, Pittsburgh, Pennsylvania (S.L.W., J.M.F.); Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania (S.L.W., J.M.F.); Department of Otolaryngology, University of Rochester, Rochester, New York (E.R.A.); Department of Otolaryngology, Michigan Medicine, University of Michigan, Ann Arbor (W.J.C.); Army-Baylor University Doctoral Program in Physical Therapy, Fort Sam Houston, Texas (C.W.H.); Otolaryngology, University of Colorado School of Medicine, Denver (S.P.C.); Department of Physical Therapy, The University of Alabama at Birmingham, Birmingham (J.B.C.); Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas (H.S.C.); Balance Disorders and Vestibular Neurology, Barrow Neurological Institute, Phoenix, and Department of Neurology, University of Arizona College of Medicine, Phoenix, Arizona (T.D.F.); Otorhinolaryngology, Mayo College of Medicine, Rochester, Minnesota (N.T.S.); Department of Orthopaedics, Doctor of Physical Therapy Division and Department of Head and Neck Surgery & Communication Sciences, Duke University Medical Center, Durham, North Carolina (R.A.C.); College of Chiropractic, Parker University, Dallas, Texas (J.D.D.); Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, Saint Louis, Missouri (J.A.G.); Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland (D.M.); Vestibular Disorders Association (VeDA), Portland, Oregon (C.R.); and Quillen College of Medicine Library, East Tennessee State University, Johnson City (N.J.W., R.L.W.).

Background: Uncompensated vestibular hypofunction can result in symptoms of dizziness, imbalance, and/or oscillopsia, gaze and gait instability, and impaired navigation and spatial orientation; thus, may negatively impact an individual's quality of life, ability to perform activities of daily living, drive, and work. It is estimated that one-third of adults in the United States have vestibular dysfunction and the incidence increases with age. There is strong evidence supporting vestibular physical therapy for reducing symptoms, improving gaze and postural stability, and improving function in individuals with vestibular hypofunction. Read More

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Outcomes of Stapedotomy in Patients With Concomitant Otosclerosis and Superior Semicircular Canal Dehiscence: Should a Radiographic Third-Window Be a Contraindication to Stapes Surgery?

Otol Neurotol 2022 02;43(2):165-169

Department of Neurotology, Michigan Ear Institute, Farmington Hills, Michigan.

Objective: Review surgical outcomes of stapedotomy in patients with concomitant otosclerosis and superior semicircular canal dehiscence.

Study Design: Retrospective case review.

Setting: Tertiary referral center. Read More

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February 2022

Vestibular compensation of otolith graviceptive dysfunction in stroke patients.

Eur J Neurol 2022 03 1;29(3):905-909. Epub 2021 Dec 1.

Department of Neurology, University Hospital, Ludwig-Maximilians-University, Munich, Germany.

Background And Purpose: A sensitive and frequent clinical sign of a vestibular tone imbalance is the tilt of the perceived subjective visual vertical (SVV). There are no data yet focusing on lesion location at the cortical level as a factor for predicting compensation from the tilt of the SVV.

Methods: With modern voxelwise lesion behavior mapping analysis, the present study determines whether lesion location in 23 right-hemispheric cortical stroke patients with an otolith dysfunction could predict the compensation of a vestibular tone imbalance in the chronic stage. Read More

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Nystagmus: Diagnosis, Topographic Anatomical Localization and Therapy.

Klin Monbl Augenheilkd 2021 Nov 16;238(11):1186-1195. Epub 2021 Nov 16.

Neurologische Klinik der Universität zu Lübeck, Deutschland.

Nystagmus is defined as rhythmic, most often involuntary eye movements. It normally consists of a slow (pathological) drift of the eyes, followed by a fast central compensatory movement back to the primary position (refixation saccade). The direction, however, is reported according to the fast phase. Read More

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November 2021

Effects of Antihypertensive Deprescribing Strategies on Blood Pressure, Adverse Events, and Orthostatic Symptoms in Older Adults: Results From TONE.

Am J Hypertens 2022 04;35(4):337-346

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

Background: The Trial of Nonpharmacologic Interventions in the Elderly (TONE) demonstrated the efficacy of weight loss and sodium reduction to reduce hypertension medication use in older adults. However, the longer-term effects of drug withdrawal (DW) on blood pressure (BP), adverse events, and orthostatic symptoms were not reported.

Methods: TONE enrolled adults, ages 60-80 years, receiving treatment with a single antihypertensive and systolic BP (SBP)/diastolic BP <145/<85 mm Hg. Read More

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