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Otolaryngol Head Neck Surg 2019 Apr 23:194599819844961. Epub 2019 Apr 23.

1 Norwegian National Advisory Unit on Vestibular Disorders, Haukeland University Hospital, Bergen, Norway.

Objective: To evaluate the association between hearing and postural balance.

Study Design: Retrospective cross-sectional study.

Setting: Tertiary care otolaryngology clinic. Read More

Adv Otorhinolaryngol 2019 15;82:143-149. Epub 2019 Jan 15.

Aging in vestibular structures with loss of hair cells in the inner ear starts early in life, but vestibular function usually remains relatively unimpaired up to advanced ages. However, dizziness and imbalance are common in the elderly and have substantial impact on the quality of life. Dizziness interferes with the everyday activities of 30% of persons over age 70. Read More

Adv Otorhinolaryngol 2019 15;82:127-133. Epub 2019 Jan 15.

Head motion recorded by the vestibular labyrinths is conveyed to specific brainstem and cerebellar structures that relay velocity information to eye muscles to stabilize vision, and to the axial and limb muscles necessary to stabilize balance. Neural networks enhance and extend the primary vestibular signal, and create adaptation to movement when appropriate. Pathological lesions to one or more of these structures may cause central vertigo and imbalance, and may be localized by specific forms of nystagmus and other abnormal neurological signs. Read More

Adv Otorhinolaryngol 2019 15;82:56-66. Epub 2019 Jan 15.

The bedside head impulse, first described nearly 20 years ago, is the single most useful clinical test of the human vestibulo-ocular reflex (VOR). The video head impulse test (vHIT), its laboratory counterpart, now enables the objective assessment of the VOR. We examine how the vHIT can be utilized in three common clinical scenarios: the acute vestibular syndrome, recurrent spontaneous vertigo, and chronic imbalance. Read More

Adv Otorhinolaryngol 2019 15;82:164-169. Epub 2019 Jan 15.

Vestibular rehabilitation is an exercise-based program that has been in existence for over 70 years. A growing body of evidence supports the use of vestibular rehabilitation in patients with vestibular disorders, and evolving research has led to more efficacious interventions. Through central compensation, vestibular rehabilitation is able to improve symptoms of imbalance, falls, fear of falling, oscillopsia, dizziness, vertigo, motion sensitivity and secondary symptoms such as nausea and anxiety. Read More

J Stroke Cerebrovasc Dis 2019 Mar 28. Epub 2019 Mar 28.

Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address:

Background: Dizziness is the most common posterior circulation symptom; however, diagnosing a posterior circulation infarction is difficult due to a lack of typical symptoms. We aimed to investigate the frequency of misdiagnosis of a posterior circulation infarction in patients who presented with dizziness and to develop a new stroke scale that increased the diagnostic accuracy for stroke among these subjects.

Methods: We retrospectively analyzed consecutive data from subjects hospitalized with ischemic stroke who presented with dizziness (the developmental phase). Read More

World Neurosurg 2019 Mar 21. Epub 2019 Mar 21.

The Ohio State University Wexner Medical Center, Department of Neurological Surgery, Columbus, OH. 43210. USA. Electronic address:

Background: Dysplastic gangliocytoma (Lhermitte-Duclos disease, LDD) typically presents as a PTEN-positive, insidious unilateral mass of the cerebellar cortex. Patients may present with symptoms of increased intracranial pressure. MRI reveals a characteristic laminar/tigroid appearance. Read More

Subcell Biochem 2019;91:195-225

Department of Neurology and German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Munich, Germany.

The world's population is ageing due to increased hygiene and improved medical care. Dizziness and imbalance frequently affect the elderly and is most common among individuals over the age of 60. In this age group approximately 30% of the population experience these debilitating symptoms at some point. Read More

Curr Neurol Neurosci Rep 2019 Mar 16;19(5):19. Epub 2019 Mar 16.

Department of Neurology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

Purpose Of Review: Disorders of posture and balance cause significant patient morbidity, with reduction of quality of life as patients refrain from critical activities of daily living such as walking outside the home and driving. This review describes recent efforts to characterize visual disorders that interact with the neural integrators of positional maintenance and emerging therapies for these disorders.

Recent Findings: Abnormalities of gait and body position sense may be unrecognized by patients but are correlated with focal neurological injury (stroke). Read More

Ear Nose Throat J 2019 Jan 30;98(1):37-43. Epub 2019 Jan 30.

3 Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Imbalance is a major health problem affecting 90 million Americans and is the primary risk factor in falls, which consume $50 billion annually in medical costs (US). A person is often unaware of their balance challenge and its potential impact on fall risk and subsequent injury. Even when balance deficits and fall risk are realized, older patients may not pursue intervention for their disorder due to a fatalistic view of their advanced age. Read More

J Head Trauma Rehabil 2019 Feb 27. Epub 2019 Feb 27.

School of Psychology, University of Kent, Canterbury, United Kingdom (Ms Denby and Dr Wilkinson); Combat Stress, Tyrwhitt House, Leatherhead, United Kingdom (Dr Murphy and Mr Busuttil); King's Centre for Military Health Research, King's College, London, United Kingdom (Dr Murphy); and East Kent Neuro-Rehabilitation Service, East Kent Hospitals University, NHS Foundation Trust Canterbury, United Kingdom (Mr Sakel).

Objective: To estimate the frequency of vestibular dysfunction following blunt, blast, and combined blunt and blast mild traumatic brain injury (mTBI) and thereon assess the long-term impact of vestibular dysfunction on neurobehavioral function and disability independently of comorbid psychiatric symptoms.

Setting: Combat Stress residential and Veterans' Outreach drop-in centers for psychological support.

Participants: One hundred sixty-two help-seeking UK military veterans. Read More

Neurosurgery 2019 Mar 4. Epub 2019 Mar 4.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.

Background: Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis. Up to 50% of patients develop central nervous system involvement, and a subset of these patients can present with isolated tumor-like masses.

Objective: To describe the skull base manifestations of ECD with an emphasis on aspects most pertinent to surgeons who may be referred such patients for primary evaluation. Read More

Med Clin North Am 2019 Mar 3;103(2):191-201. Epub 2018 Dec 3.

Department of Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Massachusetts Eye and Ear Balance and Vestibular Center, 250 Pond Street, Braintree, MA 02184, USA. Electronic address:

Dizziness and imbalance are common and challenging chief complaints carrying high morbidity, due to their association with falls, injuries, and loss of quality of life. The physical examination represents an opportunity to collect objective clinical data that facilitate an understanding of symptoms that might otherwise be enigmatic and ineffable. This review focuses on the examination techniques used routinely by physicians who provide specialized care for patients with dizziness and imbalance. Read More

Acta Otolaryngol 2019 Jan 21;139(1):6-10. Epub 2019 Jan 21.

a Department of Otolaryngology , University of Medicine , Sao Paulo , Brazil.

Background: Cochlear implantation (CI) is the gold standard therapy for profound or severe sensorineural hearing loss. It is a safe surgical procedure but, because of the proximity of the cochlea and vestibule, postoperative vestibular disorder may occur. Our hypothesis is that the video head impulse test (vHIT) may be a good tool to achieve a topographic diagnosis of dizziness in the early postoperative period after CI. Read More

Neurochirurgie 2019 Feb 16;65(1):20-26. Epub 2019 Jan 16.

Service de neurochirurgie, CHU de Limoges, 87000 Limoges, France. Electronic address:

Introduction: Vestibular neurotomy is a functional surgery for Meniere's disease in the event of medical treatment failure. The aim of the study was to assess the efficacy and complications of vestibular neurotomy, and to address the question of postoperative compensation.

Material And Method: All patients included in this retrospective study underwent a vestibular neurotomy at our center between 2009 and 2016. Read More

Neurosurg Rev 2019 Jan 9. Epub 2019 Jan 9.

Medical University of South Carolina, Charleston, SC, USA.

A great deal of literature has drawn attention to the "complex Chiari," wherein the presence of instability or ventral brainstem compression prompts consideration for addressing both concerns at the time of surgery. This report addresses the clinical and radiological features and surgical outcomes in a consecutive series of subjects with hereditary connective tissue disorders (HCTD) and Chiari malformation. In 2011 and 2012, 22 consecutive patients with cervical medullary syndrome and geneticist-confirmed hereditary connective tissue disorder (HCTD), with Chiari malformation (type 1 or 0) and kyphotic clivo-axial angle (CXA) enrolled in the IRB-approved study (IRB# 10-036-06: GBMC). Read More

BMJ Case Rep 2019 Jan 7;12(1). Epub 2019 Jan 7.

Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

A 26-year-old patient of limited cutaneous sclerosis presented to us with insidious-onset posterior fossa symptoms of headache, vomiting, vertigo and gait imbalance, progressing over a period of 3 weeks. A diagnosis of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids was made by combining the clinical features with radiological evidence showing punctate infiltration of the pons, brainstem and cerebellum. Relevant differentials in the form of neurosarcoid, infections, central nervous system (CNS) lymphoma and Neuro-Behcet's disease were ruled out by history and investigations. Read More

Semin Speech Lang 2019 Feb 7;40(1):36-47. Epub 2019 Jan 7.

Physical Therapy Program, Mary Baldwin University, Staunton, Virginia.

Rehabilitation for individuals after mild traumatic brain injury (mTBI) or concussion requires emphasis on both cognitive and physical rest, with a gradual return to activity including sports. As the client becomes more active, the rehabilitation professional should pay close attention to symptoms associated with mTBI, such as headache, dizziness, nausea, and difficulty concentrating. The systematic approach to return to play provided by the Berlin Consensus Statement on Concussion in Sport can apply to adults with mTBI. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):950-953

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Center for Vertigo and Imbalance, 200233 Shanghai, China.

Persistent geotropic direction-changing positional nystagmus (DCPN) has been described in recent years as no latency or fatigability but a null plane when head is turned toward the affected side. Different from the canalolithiasis of horizontal semicircular canal, it is similar with cupulolithiasis, but the direction of nystagmus are opposite. Light cupula theory has been used to explain the characteristics of this unique nystagmus. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;53(12):899-903

National Center for Children's Health of China, Department of Otorhinolaryngology Head and Neck Surgery, Beijing Children' s Hospital, Capital Medical University, Beijing Key Laboratory for Pediatric Diseases of Otolaryngology-Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing 100045, China.

To investigate the clinical characteristics, prognosis and affected branches of vestibular neuritis in children. Twenty-five patients with vestibular neuritis in ENT department, Beijing Children's Hospital, from October 2015 to October 2016, were collected. All patients were 4-14 (mean 9. Read More

Handb Clin Neurol 2018 ;158:163-178

Department of Neurology, Boston University School of Medicine, Boston, MA, United States. Electronic address:

Postconcussion syndrome (PCS) is a heterogeneous condition comprised of a set of signs and symptoms in somatic, cognitive, and emotional domains. PCS is a controversial concept because of differing consensus criteria, variability in presentation, and lack of specificity to concussion. Whereas symptoms of concussion resolve in most individuals over days to weeks, a minority of individuals experience symptoms persisting months to years. Read More

Handb Clin Neurol 2018 ;159:385-401

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Read More

F1000Res 2018 15;7. Epub 2018 Aug 15.

Clinique du Vertige, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg.

Ménière's disease (MD) represents a heterogeneous group of relatively rare disorders with three core symptoms: episodic vertigo, tinnitus, and sensorineural hearing loss involving 125 to 2,000 Hz frequencies. The majority of cases are considered sporadic, although familial aggregation has been recognized in European and Korean populations, and the search for familial MD genes has been elusive until the last few years. Detailed phenotyping and cluster analyses have found several clinical predictors for different subgroups of patients, which may indicate different mechanisms, including genetic and immune factors. Read More

J Neurosci 2019 Jan 9;39(3):420-433. Epub 2018 Nov 9.

State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology, School of Life Sciences, and

Vestibular compensation is responsible for the spontaneous recovery of postural, locomotor, and oculomotor dysfunctions in patients with peripheral vestibular lesion or posterior circulation stroke. Mechanism investigation of vestibular compensation is of great importance in both facilitating recovery of vestibular function and understanding the postlesion functional plasticity in the adult CNS. Here, we report that postsynaptic histamine H1 receptor contributes greatly to facilitating vestibular compensation. Read More

Korean J Neurotrauma 2018 Oct 31;14(2):159-163. Epub 2018 Oct 31.

Department of Neurosurgery, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.

We describe the case of a patient who had infarction of the posterior inferior cerebellar artery (PICA) after a chiropractic cervical manipulation. A 39-year-old man visited the emergency room with signs of cerebellar dysfunction, presenting with a 6-hour history of vertigo and imbalance. Two weeks ago, he was treated by a chiropractor for intermittent neck pain. Read More

J Neurol 2018 Dec 19;265(12):2993-3000. Epub 2018 Oct 19.

Department of Neurology, College of Medicine, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, 179, Gudeok-ro, Seo-gu, 602-739, Busan, South Korea.

The aim of this study was to determine the frequency, clinical and radiological features, and efficacy of clinical evaluation and perfusion-weighted imaging (PWI) for the prediction of final stroke in patients with DWI/MRI-negative posterior circulation stroke (PCS) presenting acute dizziness/vertigo. From our comprehensive prospective stroke registry of acute ischemic stroke during a 7-year period, we identified 1846 consecutive patients with PCS, 850 of whom presented with acute dizziness/vertigo. Of these 850 patients, initial DWI-MRI was negative in 35 (4. Read More

Physiother Theory Pract 2018 Oct 17:1-8. Epub 2018 Oct 17.

a Department of Physiotherapy, Western Health , Sunshine Hospital , St Albans , Victoria , Australia.

Aim: To determine whether patients presenting to the emergency department (ED) with possible benign paroxysmal positional vertigo (BPPV) are managed in accordance with best practice guidelines, and whether physiotherapists are involved in their care.

Design: Retrospective observational study.

Participants: Ninety-six consecutive patients presenting to one of three EDs with vertigo, dizziness or imbalance symptoms documented at triage. Read More

Eur Arch Otorhinolaryngol 2018 Nov 9;275(11):2705-2711. Epub 2018 Oct 9.

King Abdulaziz University, Jeddah, Saudi Arabia.

Background And Objective: Benign paroxysmal positional vertigo (BPPV) is an idiopathic recurrent inner ear illness that is caused most often by an imbalance in the metabolism of calcium carbonate crystals (otoconia) inside the semicircular canals, in which the otoconia begin to circulate freely after being dislodged from the basic structure. The underlying etiology of this imbalance has not yet been well established; however, a few recent articles have revealed that vitamin D level abnormality in these patients might play a role. Therefore, we conducted the current systematic review analysis to explore potential associations of vitamin D level with the occurrence as well as the recurrence of BPPV disease. Read More

Ear Nose Throat J 2018 Sep;97(9):278-282

Department of Emergency, Izmir Medicalpark Hospital, Izmir, Turkey.

We aim to demonstrate possible autonomic dysfunction based on salivary α-amylase measurements during and after the vertigo attacks associated with Ménière disease (MD) and benign paroxysmal positional vertigo (BPPV). Patients admitted to the emergency room with a diagnosis of vertigo attacks caused by either MD (n = 15) or BPPV (n = 9) constituted the study groups. The control group (n = 10) consisted of volunteer patients admitted to the emergency department with minor soft-tissue trauma. Read More

J Int Adv Otol 2018 Aug;14(2):299-303

Department of Medical Biochemistry, Dışkapı Yıldırım Beyazıt Training and Resarch Hospital, Ankara, Turkey.

Objective: Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vestibular disorder and is particularly seen among older patients suffering from vertigo. The brief vertigo attacks in and imbalance symptoms of BPPV are caused by freely floating otoconia within the semicircular canals. The aim of this prospective study was to evaluate the role of oxidative stress, using native thiol/disulfide (SH/SS) homeostasis as a novel indicator, in the etiology of BPPV. Read More

Indian J Otolaryngol Head Neck Surg 2018 Sep 13;70(3):428-433. Epub 2018 Jul 13.

2Department of ENT, MGM Medical College and MY Hospital, Indore, M.P. India.

Elderly population is frequently affected by vertigo which affects their mobility and makes them vulnerable to fall and other morbidities. Often these patient visit neurologist and are often subjected to CT scan, MRI brain etc. to rule out a central cause of vertigo; whereas majority of these patients suffer from vestibular cause of vertigo. Read More

J Stroke Cerebrovasc Dis 2018 Dec 8;27(12):3419-3424. Epub 2018 Sep 8.

SUNY Downstate Medical Center, The Stroke Center and Department of Neurology and Kings County Hospital Center, Department of Neurology, Brooklyn, New York.

Objects: To identify predictors of acute ischemic stroke (AIS) among patients presenting to the Emergency Department (ED) with dizziness, imbalance, or vertigo (DIV) based on demographic and clinical characteristics.

Methods: We identified patients admitted to the hospital after presenting to the ED with DIV from the Statewide Planning and Research Cooperative System database of New York from 2010 to 2014. Demographic and clinical characteristics were systematically collected. Read More

Otol Neurotol 2018 Oct;39(9):1153-1162

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary.

Objective: Evaluate the relationship between objective audiometric and vestibular tests and patient symptoms in superior canal dehiscence (SCD) syndrome.

Study Design: Retrospective chart review.

Setting: Tertiary care center. Read More

Ideggyogy Sz 2018 Jul;71(7-08):221-235

Petz Aladár Megyei Oktató Kórház, Fül-Orr-Gégészeti és Fej-, Nyaksebészeti Osztály, Gyôr.

Dizziness is one of the most common causes of medical visits. Management of the dizzy patient may be challenging both for the general practitioner, in emergency departments, and special clinics, as behind a seemingly homogeneous clinical presentation several very different etiologies may occur. Research of the last two century enriched our knowledge about physiology and pathophysiology of the vestibular system. Read More

J Neurol 2018 Oct 6;265(Suppl 1):40-43. Epub 2018 Aug 6.

Department of Neurology and German Center for Vertigo and Balance Disorders, Campus Grosshadern, Ludwig Maximilians University, Munich, Marchioninistr. 15, 81377, Munich, Germany.

Otol Neurotol 2018 Sep;39(8):e699-e703

Department of Otolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University.

Objective: To evaluate the objective and subjective effects of intratympanic gentamicin treatment in patients with small vestibular schwannomas who exhibit intractable vertigo.

Patients: Individuals diagnosed with small vestibular schwannomas who exhibited intractable vertigo were retrospectively reviewed.

Interventions: Intratympanic gentamicin injection. Read More

Int Tinnitus J 2018 Jun 1;22(1):30-34. Epub 2018 Jun 1.

Department of Biological Sciences and Health, Tuiuti University of Paraná.

Background: Patients with any type of temporomandibular disorder (TMD) may have several symptoms in their temporomandibular joints, masticatory muscles and associated structures, and may have otological symptoms such as tinnitus, ear fullness, ear pain, hearing loss, hyperacusis, and vertigo, which may be due to the anatomical proximity between the temporomandibular joint, muscles innervated by the trigeminal nerve, and ear structures. Objective: This study found a prevalence of ear complaints described in the medical records of patients (n = 485) at the Center for Diagnosis and Treatment of the Temporomandibular Joint and Dental-Facial Functional Alterations at Tuiuti University of Paraná (CDATM/UTP), with TMD evaluated by the Research Diagnostic Criteria/Temporomandibular Disorders (RDC/ TMD).

Method: After approval by the ethics committee were examined 485 medical records of patients of the CDATM/UTP, of both sexes a period of 2 years. Read More

Front Neurol 2018 6;9:422. Epub 2018 Jun 6.

Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

Superficial siderosis (SS) is a rare condition in which hemosiderin, an iron storage complex, is deposited in neural tissues because of recurrent subarachnoid bleeding. Hemosiderin deposition in the vestibulocochlear nerve (CN VIII), brain, spinal cord and peripheral nerve can cause sensorineural hearing loss (SNHL) and postural imbalance, but much remains unknown about the vestibular manifestations of SS. To report the clinical course, cochleovestibular status, and patterns of vestibulopathy during follow-up of a relatively large case series, and to discuss the possible pathophysiological mechanism of vestibular deterioration. Read More

Front Neurol 2018 4;9:352. Epub 2018 Jun 4.

Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, Netherlands.

Objective: To systematically review the symptoms reported by patients with bilateral vestibulopathy (BV) in clinical studies and case reports. This would serve as the first step in establishing a validated patient-reported outcome measures (PROM) for BV.

Methods: A search on symptoms reported by patients with BV was performed in PubMed, and all publications covering these symptoms were included. Read More

Otol Neurotol 2018 Oct;39(9):1191-1194

Department of Otolaryngology-Head and Neck Surgery.

Objective: To describe the incidence of intralabyrinthine schwannoma (ILS) utilizing the Rochester Epidemiology Project (REP), a unique medical consortium in the United States that covers a complete population of all ages in a well-defined geographic area over the past half-century.

Patients: All patients with ILS diagnosed between January 1, 1966 and December 31, 2016 in Olmsted County, Minnesota, identified using the REP medical records-linkage system.

Main Outcome Measures: Incidence of ILS. Read More

Front Neurol 2018 14;9:297. Epub 2018 May 14.

Department of Neuroscience, Baylor College of Medicine, Houston, TX, United States.

The increased use of close range explosives has led to a higher incidence of exposure to blast-related head trauma. Exposure to primary blast waves is a significant cause of morbidity and mortality. Active service members and civilians who have experienced blast waves report high rates of vestibular dysfunction, such as vertigo, oscillopsia, imbalance, and dizziness. Read More

F1000Res 2018 5;7:276. Epub 2018 Mar 5.

Physiotherapy Department, Faculty of Applied Medical Sciences, Umm-Al-Qura University, Mecca, 21421, Saudi Arabia.

Dizziness is a non-specific term used by patients to describe several symptoms ranging from true vertigo, light headedness, disorientation or sense of imbalance. Vestibular rehabilitation (VR) is a specific form of exercise-based therapy programme aimed at alleviating the primary and secondary problems of a vestibular pathology. The aim of this study was to investigate the effectiveness of exercise-based vestibular rehabilitation in adult patients with chronic dizziness. Read More

J Int Adv Otol 2018 Apr;14(1):106-111

Department of Neurosciences, Institute of Otolaryngology, Padova University School of Medicine, Padova, Italy.

The goal of the present study was to describe a case of perilymphatic fistula (PLF) of the round window (RW) that occurred after sneezing, along with a review of the literature. We report a case of PLF of RW, which was provoked by sneezing, and its consequent medical and surgical treatments. With respect to the review of the literature, articles were initially selected based on their titles or abstracts, followed by methodological evaluation. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jan;32(2):99-102

Department of Otolaryngology,the General Hospital of Tianjin Medical University Tianjin,300052,China Department of Otolaryngology,Tianjin Medical University General Hospital Airport Hospitial.

To investigate the changes of vedionystamography(VNG)in patients with posterior circulation ischemia vertigo(PCIV).Fifty patients who complained of vertigo and imbalance with PCI were selected as experimental group for testing of visual nystamography(VNG).Thirty normal subjects were chosen as control group. Read More

Int J Immunopathol Pharmacol 2018 Jan-Dec;32:2058738418773833

3 UOSD Audiovestibology G. Rummo Hospital, Benevento, Italy.

It is a well-known fact that inner ear diseases are often caused by microcirculatory disorders, and the recent literature is oriented towards investigations into the relationship between the cardiovascular system and cochleovestibular illness with related classical symptoms: tinnitus, hearing loss, and vertigo or instability. These symptoms, and particularly the vertigo, may be the alarm signal of microcirculatory disorders of the labyrinth or vertebrobasilar circulation so as to represent a possible symptom of posterior circulation stroke. The treatment aimed at correcting the haemodynamic and metabolic imbalance, generated by the cochleovestibular microcirculatory disorders, with drugs that act on the vessel wall being very useful, both alone and in combination with other treatment protocols. Read More

Acta Neurol Scand 2018 Oct 16;138(4):270-277. Epub 2018 Apr 16.

Department of Medicine, Neurologic Clinic, Headache Centre, University of Perugia, Perugia, Italy.

Objectives: This observational study aimed to investigate the presence of potential vestibular system subclinical dysfunction among migraineurs without a history of vertigo and dizziness compared with healthy controls.

Methods: Patients diagnosed with episodic migraine with and without aura were enrolled. All patients and healthy controls underwent vestibular examination using the following conventional tests: sitting position, Pagnini-McClure's, Dix-Hallpike's, head hanging, video head impulse, subjective visual vertical, Romberg, Fukuda, and caloric vestibular stimulation by Fitzgerald-Hallpike's tests. Read More

Orv Hetil 2018 Mar;159(12):470-477

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Szigony u. 36., 1083.

Introduction: Physicians are found to have a great and increasing amount of patients suffering of vertigo in their everyday practice. For the treatment of the balance disorders, a vestibular training was introduced which played an influential role based on our study.

Aim: Our aim was to create an easy and comprehensible training program which can be performed even with a family member. Read More

Clin Neurophysiol 2018 May 5;129(5):934-945. Epub 2018 Mar 5.

Department of Neurology, University Hospital Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland. Electronic address:

Objective: Gait imbalance in patients with bilateral-vestibular-deficiency (BVD) was linked to increased variability in perceived direction of gravity while upright. We hypothesized this to be true also when roll-tilted. Moreover, as utricular input is essential for spatial orientation, we predicted the variability of perceived vertical to correlate inversely with utricular function. Read More

J Neurol 2018 May 16;265(5):1184-1198. Epub 2018 Mar 16.

German Center for Vertigo and Balance Disorders, Ludwig-Maximilians Universität, Munich, Germany.

A retrospective clinical study focused on the frequency of rotational vertigo in 63 patients with acute unilateral midbrain strokes involving the vestibular and ocular motor systems. In contrast to unilateral pontomedullary brainstem lesions, rotational vertigo in midbrain lesions occurred with a low frequency (14%) and transient (< 1 day) course. Swaying vertigo or unspecific dizziness (22%) and postural imbalance (31%) were more frequent. Read More

Front Immunol 2017 13;8:1739. Epub 2017 Dec 13.

Otology and Neurotology Group CTS495, Department of Genomic Medicine - Centre for Genomics and Oncological Research - Pfizer/Universidad de Granada/Junta de Andalucía (GENYO), Granada, Spain.

Meniere's disease (MD) is a rare disorder characterized by episodic vertigo, sensorineural hearing loss, tinnitus, and aural fullness. It is associated with a fluid imbalance between the secretion of endolymph in the cochlear duct and its reabsorption into the subarachnoid space, leading to an accumulation of endolymph in the inner ear. Epidemiological evidence, including familial aggregation, indicates a genetic contribution and a consistent association with autoimmune diseases (AD). Read More