945 results match your criteria Distraction Osteogenesis of the Maxilla


Does the Rigid External Distraction Device Alter Maxillary Pitch in Cleft Maxillary Distraction?

Cleft Palate Craniofac J 2022 Jun 22:10556656221109413. Epub 2022 Jun 22.

83488University of Alabama at Birmingham School of Dentistry, Birmingham, AL, USA.

The rigid external distraction (RED) device is reported to have the ability to three-dimensionally reposition the maxilla. The purpose of this study is to assess the ability of RED to intentionally alter the maxillary pitch.

Retrospective cohort study. Read More

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Collagen membrane and distraction osteogenesis for correcting alveolar bone defects: An animal pilot study.

J World Fed Orthod 2022 Jun 7. Epub 2022 Jun 7.

Department of Orthodontics, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Background: The objective of this study was to evaluate the applicability of distraction osteogenesis with or without collagen membrane coverage to approximate the bone surfaces surrounding alveolar defects in pigs.

Methods: The sample comprised six pigs. One animal was control, and in the other five, alveolar bone defects were created and distraction osteogenesis was carried out to approximate adjacent bone surfaces in the defect site. Read More

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Influence of Bone-Borne Trans-Sutural Distraction Osteogenesis Therapy on the Hard Palate of Growing Children With Cleft Lip and Palate.

J Craniofac Surg 2022 Mar-Apr 01;33(2):390-394

Department of Plastic and Reconstructive Surgery, Peking University Third Hospital, Haidian District.

Abstract: The efficacy of trans-sutural distraction osteogenesis therapy (TSDO) in treating midfacial hypoplasia in children with cleft lip and palate has been confirmed. However, few studies have reported that changes occur in the palate after TSDO treatment. To study the effect of TSDO on palatal morphology and its relative position in the craniofacial region, we retrospectively collected and measured the computed tomography images of 29 growing children with cleft lip and palate and midfacial hypoplasia, before and after TSDO. Read More

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Commentary on "A Minimally Invasive Nasal Endoscopic Approach to Distraction Osteogenesis Maxillary Expansion to Restore Nasal Breathing for Adults with Narrow Maxilla" by Liu et al.

Facial Plast Surg Aesthet Med 2022 Feb 17. Epub 2022 Feb 17.

Otolaryngology, Medical School, Federal University of Uberlandia, Uberlandia, Brazil.

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February 2022

A Minimally Invasive Nasal Endoscopic Approach to Distraction Osteogenesis Maxillary Expansion to Restore Nasal Breathing for Adults with Narrow Maxilla.

Facial Plast Surg Aesthet Med 2022 Feb 17. Epub 2022 Feb 17.

Division of Sleep Medicine, Department of Psychiatry, Stanford University School of Medicine, Stanford, California, USA.

Patients with narrow high-arch palate present with limited response to standard septal, turbinate, and valve procedures for nasal obstruction. To measure the effectiveness of minimally invasive nasal endoscopic (MINE) Lefort I osteotomy among subjects with narrow high-arched palate in managing nasal obstruction. Prospective cohort study was performed where subjects with narrow high-arched palate underwent MINE distraction osteogenesis maxillary expansion (DOME) from August 2019 to January 2021. Read More

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February 2022

[Factors associated with the outcome of maxillary distraction osteogenesis in cleft lip and palate patients].

Authors:
J P Si L Lyu X Y Chen

Zhonghua Kou Qiang Yi Xue Za Zhi 2021 Dec;56(12):1271-1276

Department of Orthodontic, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine & Zhejiang Provincial Clinical Research Center for Oral Diseases & Key Laboratory of Oral Biomedical Research of Zhejiang Province & Cancer Center of Zhejiang University, Hangzhou 310006, China.

Since distraction osteogenesis had been used in maxillofacial surgery in the 1990s,it has become an important option for treating maxillary hypoplasia in cleft lip and palate (CLP) patients. Numerous domestic and international studies reported that the prognosis of distraction osteogenesis might be affected by various factors, including the design of osteotomy line, type of distractor, advancement of maxillary bone and the age of patients, etc. Therefore, the present article reviewed possible impact factors that affect the effectiveness and outcomes of maxillary distraction osteogenesis of CLP from three aspects: treatment methods, type of patients and adjuvant therapy, which hopefully might benefit the formulation of treatment strategies in clinical work and improve the prognosis of distraction osteogenesis. Read More

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December 2021

Sutural fibroblasts exhibit the function of vascular endothelial cells upon mechanical strain.

Arch Biochem Biophys 2021 11 29;712:109046. Epub 2021 Sep 29.

Peking University Third Hospital, Beijing, China. Electronic address:

Midfacial hypoplasia is a type of facial dysplasia. The technique of trans-sutural distraction osteogenesis promotes midface growth so as to ameliorate this symptom. In the process of distraction osteogenesis, the fiber matrix in the suture acts as a mechanical sensor. Read More

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November 2021

Relapse-related factors of Le Fort I osteotomy in cleft lip and palate patients: A systematic review and meta-analysis.

J Craniomaxillofac Surg 2021 Oct 10;49(10):879-890. Epub 2021 Sep 10.

Institute of Maxillofacial Surgery, Teknon Medical Center Barcelona, Barcelona, Spain; Department of Oral and Maxillofacial Surgery, Universitat Internacional de Catalunya, Sant Cugat Del Vallès, Barcelona, Spain.

A systematic review search was based on the PICOS approach, as follows: population: cleft lip and palate patients; intervention: Le Fort I osteotomy; comparator: different surgical protocols; outcome: stability, recurrence or surgical complications; study designs: only case reports were excluded from the review. No restrictions were placed on language or year of publication. Risk of bias was analyzed, heterogeneity was assessed, and subgroup analysis was performed using a level of significance of 1% (p = 0. Read More

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October 2021

Accuracy of Virtually Planned Maxillary Distraction in Cleft Patients - An Evaluative Study.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):49-57. Epub 2021 Feb 18.

Department of Oral Medicine, Universitat Internacional de Catalunya, Spain.

Introduction: Maxillary distraction may be used to treat severe maxillary hypoplasia in cleft lip and palate (CLP) patients. Three-dimensional (3D) planning has been shown to increase the accuracy of distraction and reduce operative time and complications. The aim of the study was to measure the accuracy of internal maxillary distraction after 3D planning in CLP patients, to add evidence to validate the virtual osteotomy and distraction procedure. Read More

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February 2021

Bone formation after surgically assisted rapid maxillary expansion: comparison of 2 distraction osteogenesis protocols.

Oral Surg Oral Med Oral Pathol Oral Radiol 2022 03 26;133(3):271-276. Epub 2021 Jun 26.

Department of Diagnosis and Surgery, Dental School of Araraquara, São Paulo State University.

Objective: The aim of this study was to compare bone formation between 2 distraction osteogenesis protocols by analyzing cone beam computed tomography (CBCT) scan data.

Study Design: In this retrospective study, the efficacy of 2 different surgically assisted rapid maxillary expansion protocols (group 1 [G1], 3 × 0.25 mm/d; group 2 [G2], 1 mm start followed by 2 × 0. Read More

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Pre-bent Buccal Distractor Made from a 3D Model for Maxillary Anterior Segmental Distraction Osteogenesis for Precious Fit and Decreasing Surgical Time.

J Maxillofac Oral Surg 2021 Sep 29;20(3):507-509. Epub 2020 Oct 29.

Department of Oral and Maxillofacial Surgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 Japan.

Maxillary anterior segmental distraction osteogenesis surgery involves a distraction segment that is made at the anterior part of the maxilla. Although bending and fitting the distractor during surgery is a complex procedure, we present here a usefulness of the pre-bent distractor made with a 3D model for precise fixing and reducing the operative time. Read More

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September 2021

Cleft Lip and Palate Midfacial Hypoplasia: Criteria to Choose the Treatment.

J Craniofac Surg 2022 Mar-Apr 01;33(2):496-501

Oral and Maxillofacial Surgery Unit, Hospital Clínico Metropolitano el Carmen.

Abstract: A series of skeletal and dentoalveolar/occlusal criteria were proposed for choosing the treatment modality for the management of midface hypoplasia in cleft lip/palate patients, focusing on functional improvement, aesthetics, and minimizing the risk of recurrence and secondary alterations. For which, 42 patients with nonsyndromic cleft lip/palate, all with previous primary lip/palate surgeries and without previous osteotomies, were analyzed. Orthognathic surgery (OS) (n = 24) and maxillary distraction osteogenesis (n = 18) with anterior segmental osteotomies (segmental distraction osteogenesis [SD]), alveolar transport disc (TD), and midface total distraction osteogenesis (TDO) by modified Le Fort III osteotomy was done. Read More

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Local Soft Tissue and Bone Displacements Following Midfacial Bipartition Distraction in Apert Syndrome - Quantification Using a Semi-Automated Method.

J Craniofac Surg 2021 Nov-Dec 01;32(8):2646-2650

UCL Great Ormond Street Institute of Child Health; Craniofacial Unit, Great Ormond Street Hospital for Children.

Abstract: Patients with Apert syndrome experience midfacial hypoplasia, hypertelorism, and downslanting palpebral fissures which can be corrected by midfacial bipartition distraction with rigid external distraction device. Quantitative studies typically focus on quantifying rigid advancement and rotation postdistraction, but intrinsic shape changes of bone and soft tissue remain unknown. This study presents a method to quantify these changes. Read More

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November 2021

Outcomes of alveolar segmental 'sandwich' osteotomy with interpositional particulate allograft for severe vertical defects in the anterior maxilla and mandible.

Int J Oral Maxillofac Surg 2021 Dec 3;50(12):1617-1627. Epub 2021 Jul 3.

Division of Oral and Maxillofacial Surgery, University of Southern California, Los Angeles, CA, USA.

The purpose of this study was to report the outcomes of interpositional osteotomy with mineralized allograft in the treatment of alveolar vertical defects in preparation for implant placement. Thirteen defects (11 maxillary and two mandibular) were treated with osteotomy segments ranging in length from two to five missing teeth. The segments were positioned 5-7 mm coronally, with the gap space filled with allograft and then fixated with titanium hardware. Read More

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December 2021

Two-Stage Treatment of a Large Premaxillary Defect.

J Craniofac Surg 2021 Nov-Dec 01;32(8):2827-2829

Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine.

Abstract: Bilateral cleft lip and palate (CLP) patients commonly require surgical management to treat maxillary hypoplasia following the primary repair. Rarer is the CLP patient who also presents with a missing premaxillary segment. Here the authors present the case of a 19-year-old female with a history of bilateral CLP who demonstrated significant maxillary hypoplasia in addition to a large premaxillary defect. Read More

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November 2021

Interdisciplinary Approach for the Treatment of Complex Bilateral Cleft Lip and Palate With Missing Premaxilla.

Cleft Palate Craniofac J 2022 05 23;59(5):680-687. Epub 2021 Jun 23.

Children's Health Children's Medical Center Dallas, TX, USA.

Complex craniofacial deformities such as complete bilateral cleft lip and palate require interdisciplinary approach for proper diagnosis and treatment. A severe skeletal discrepancy caused by bilateral cleft lip and palate and missing premaxilla was successfully managed with orthodontic preparation and distraction osteogenesis. Conventional prosthodontic treatment combined with orthodontic preparation was proven to be a viable option to manage multiple missing teeth in cleft lip and palate. Read More

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Comprehensive management of Crouzon syndrome: A case report with three-year follow-up.

J Orthod 2022 Mar 8;49(1):71-78. Epub 2021 Jun 8.

Department of Orthodontics and Dentofacial Orthopedics, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Crouzon syndrome is one of the most common craniosynostosis facial syndromes caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Less commonly, there is a mutation of the FGFR3 gene which results in Crouzon syndrome syndrome with acanthosis nigricans. It involves the premature fusion of sutures of the cranial vault, base, orbital and maxillary region. Read More

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Craniofacial Distraction: Orthodontic Considerations.

Clin Plast Surg 2021 Jul 8;48(3):531-541. Epub 2021 May 8.

Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY 10017, USA. Electronic address:

A combined surgical and orthodontic approach to midface and mandibular distraction optimizes stability and outcomes. Orthodontic considerations include proper planning of the distraction vector, appropriate device use, and thorough follow-up through the consolidation and postoperative period. The dental occlusion must be managed throughout treatment in order to achieve ideal results. Read More

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Le Fort II Distraction with Simultaneous Zygomatic Repositioning.

Clin Plast Surg 2021 Jul 8;48(3):487-496. Epub 2021 May 8.

The Craniofacial Center, Seattle Children's Hospital, 4800 Sand Point Way Northeast, Seattle, WA 98105, USA.

Severe midface hypoplasia is often managed by Le Fort III distraction. Le Fort II distraction with zygomatic repositioning is a modification of the Le Fort III distraction operation aimed to correct abnormal facial ratios of patients with greater central than lateral midface deficiency. The operation starts with Le Fort III osteotomies and is followed by separation and fixation of bilateral zygomas. Read More

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Cleft Lip and Palate: Le Fort I Distraction Using an Internal Device.

Clin Plast Surg 2021 Jul 8;48(3):407-417. Epub 2021 May 8.

Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, 4650 West Sunset Boulevard, Mailstop 96, Los Angeles, CA 90033, USA; Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA; Division of Dentistry and Orthodontics, Children's Hospital Los Angeles, Los Angeles, CA, USA; Division of Oral and Maxillofacial Surgery, University of Southern California, Los Angeles, CA, USA. Electronic address:

Maxillary hypoplasia is a commonly seen dentofacial anomaly in patients with cleft lip and palate after surgical repair of the cleft anomaly. To facilitate large horizontal movements of the maxilla, distraction osteogenesis is used to slowly stretch the soft tissue envelope with the skeletal advancement preventing tissue recoil and skeletal relapse. Internal distraction devices have the advantage of reducing the amount of physical and psychological stress placed on patients, families, and caregivers. Read More

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Cleft Lip and Palate: LeFort I Distraction with Halo and Hybrid Internal Maxillary Distractors.

Clin Plast Surg 2021 Jul 8;48(3):391-405. Epub 2021 May 8.

Division of Plastic Surgery, Department of Surgery, Rush Craniofacial Center, Rush University Medical Center, 1725 West Harrison Street, Suite 425 POB 1, Chicago, IL 60612, USA.

Distraction osteogenesis is a viable treatment option for patients with a cleft associated with severe maxillary retrusion. A rigid external distraction device and a hybrid internal maxillary distractor have been used to advance the maxilla allowing for predictable and stable results. These techniques can be applied by itself or as an adjunct to traditional orthognathic procedures. Read More

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Lefort II distraction with zygomatic repositioning versus Lefort III distraction: A comparison of surgical outcomes and complications.

J Craniomaxillofac Surg 2021 Oct 28;49(10):905-913. Epub 2021 Apr 28.

Craniofacial Center, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA. Electronic address:

The aim of the study was to determine if the additional surgical complexity of Lefort II distraction with zygomatic repositioning (LF2ZR) results in increased complications compared to Lefort III distraction (LF3). A retrospective review was performed of all LF3 and LF2ZR advancements performed by the senior author over 15 years. Demographic, operative, postoperative, and cephalometric data were collected from initial procedure through greater than 1 year postoperatively. Read More

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October 2021

Distraction Osteogenesis: Mandible and Maxilla.

Facial Plast Surg 2021 Dec 3;37(6):751-758. Epub 2021 May 3.

Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.

Mandibular and maxillary deformities commonly require surgical intervention. Prior to distraction osteogenesis, traditional modalities involving single-staged translocation and rigid fixation were used to correct these craniofacial anomalies. Distraction osteogenesis has evolved as a compelling alternative for treating aesthetic and functional dentofacial defects. Read More

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December 2021

Virtual planning and CAD/CAM-assisted distraction for maxillary hypoplasia in cleft lip and palate patients: Accuracy evaluation and clinical outcome.

J Craniomaxillofac Surg 2021 Sep 21;49(9):799-808. Epub 2021 Apr 21.

Division of Maxillofacial Surgery, Città della Salute e della Scienza Hospital, University of Torino, Italy.

The aim of this prospective study was to report the experience with a specific guided distraction protocol for the treatment of CLP patients with severe midface hypoplasia. From January 2016 to April 2019, six consecutive, non-growing, CLP patients with maxillary hypoplasia underwent a specific distraction protocol based on the use of VSP, CAD/CAM-generated surgical splints, cutting guides, prebent internal maxillary distractors, early removal of distractors, and acute callus manipulation and fixation. STL files for VSP, using multislice CT scans taken preoperatively (T0) and 3 months after distractor removal (T1) were superimposed using the free software 3D Slicer and Geomagic Wrap to evaluate the accuracy of maxillary repositioning and assess 3D bone changes. Read More

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September 2021

One-Year Treatment Outcome of Profile Changes After Transcutaneous Maxillary Distraction Osteogenesis in Growing Children With Cleft Lip and Palate.

Cleft Palate Craniofac J 2022 Mar 5;59(3):299-306. Epub 2021 Apr 5.

Department of Craniofacial Orthodontics, Department of Dentistry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung.

Objective: To evaluate the long-term stability of LeFort I osteotomy followed by distraction osteogenesis with a transcutaneous rigid external device for the treatment of severe maxillary hypoplasia in patients with cleft lip and palate.

Patients And Methods: Nine patients with cleft lip and palate underwent rigid external distraction after a LeFort I osteotomy for maxillary advancement. Lateral cephalometric films were analyzed for assessment of treatment outcome and stability in 1 month, 6 months, and 1 year after distraction. Read More

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Maxillary Changes Following Facial Bipartition - A Three-Dimensional Quantification.

J Craniofac Surg 2021 Sep;32(6):2053-2057

UCL Institute of Child Health and Department of Craniofacial Surgery, Great Ormond Street Hospital for Children.

Introduction: Children with Apert syndrome have hypertelorism and midfacial hypoplasia, which can be treated with facial bipartition (FB), often aided by rigid external distraction. The technique involves a midline osteotomy that lateralizes the maxillary segments, resulting in posterior cross-bites and midline diastema. Varying degrees of spontaneous realignment of the dental arches occurs postoperatively. Read More

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September 2021

Patient experience and satisfaction of surgically assisted rapid maxillary expansion and mandibular midline distraction.

J Craniomaxillofac Surg 2021 Aug 6;49(8):649-654. Epub 2021 Feb 6.

Consultant at the Department of Oral and Maxillofacial Surgery, Erasmus MC, University Medical Center Rotterdam, the Netherlands.

Little is known regarding patient experience and satisfaction with surgically assisted rapid maxillary expansion (SARME) and mandibular midline distraction (MMD). This study therefore aimed to assess patient experience and satisfaction with these techniques in two different groups. The first group answered the post-surgical patient satisfaction questionnaire on a 7-point Likert scale during a long-term follow-up recall. Read More

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Skeletal and Dental Correction and Stability Following LeFort I Advancement in Patients With Cleft Lip and Palate With Mild, Moderate, and Severe Maxillary Hypoplasia.

Cleft Palate Craniofac J 2022 01 15;59(1):98-109. Epub 2021 Mar 15.

Hansjörg Wyss Department of Plastic Surgery, 12297NYU Langone Health, New York, NY, the United States.

Objective: This study evaluates skeletal and dental outcomes of LeFort I advancement surgery in patients with cleft lip and palate (CLP) with varying degrees of maxillary skeletal hypoplasia.

Design: Retrospective study.

Method: Lateral cephalograms were digitized at preoperative (T1), immediately postoperative (T2), and 1-year follow-up (T3) and compared to untreated unaffected controls. Read More

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January 2022

Revascularized Fibula Free Flap Reconstruction and Curvilinear Transport Distraction Osteogenesis in Closure of Large Postmaxillectomy Defects: A New Gold Standard?

Ann Maxillofac Surg 2020 Jul-Dec;10(2):304-311. Epub 2020 Jul 2.

Department of Mechanical Engineering, University of Cape Town, Rondebosch, Cape Town, South Africa.

Introduction: The revascularized fibula free flap (RFFF) is the most popular method of postmaxillectomy reconstruction. This article proves that the use of curvilinear transport distraction osteogenesis (CTDO) is an efficacious way in closing large defects in the maxilla and a superior alternative to the RFFF.

Methods And Materials: In a prospective cohort study of six postmaxillectomy patients, CTDO was applied and the new bone (regenerate) was compared with the parent bone from which it had been regenerated. Read More

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Skeletal Stability and Airway Changes After Maxillary Advancement Using a Rigid External Distraction System in Non-Growing Cleft Patients.

J Craniofac Surg 2021 Mar-Apr 01;32(2):e195-e198

Craniofacial Center, Rush University Medical Center, KLS Martin, Jacksonville, FL.

Abstract: Distraction osteogenesis (DO) is a highly effective technique for correction of severe maxillary hypoplasia, especially in patients with orofacial clefts and craniofacial syndromes. The purpose of this retrospective, longitudinal study was to assess long-term airway alterations after maxillary advancement using a rigid external distraction system (RED) in non growing cleft patients. Fifteen cleft patients (8 males and 7 females) aged from 14 to 25 years were included in this study. Read More

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