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Medicine (Baltimore) 2019 Mar;98(10):e14754

Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.

Pierre Robin sequence (PRS) is a congenital malformation characterized by micrognathia, glossocoma, and mechanical obstruction of the upper respiratory tract. These deformities impair respiration, sleep, feeding, and swallowing, and can lead to malnutrition, stunted development, and death. Bilateral mandibular distraction osteogenesis, whereby the mandible and tongue root are extended outward, is the standard treatment to relieve upper airway obstruction in severe PRS. Read More

Clin Plast Surg 2019 Apr;46(2):207-221

Craniofacial Pediatrics, Seattle Children's Hospital, 4800 Sand Point Way, M/S OB.9.528, PO Box 5371, Seattle, WA 98105, USA.

Clinicians use different diagnostic terms for patients with underdevelopment of facial features arising from the embryonic first and second pharyngeal arches, including first and second branchial arch syndrome, otomandibular dysostosis, oculoauriculovertebral syndrome, and hemifacial microsomia. Craniofacial microsomia has become the preferred term. Although no diagnostic criteria for craniofacial microsomia exist, most patients have a degree of underdevelopment of the mandible, maxilla, ear, orbit, facial soft tissue, and/or facial nerve. Read More

Plast Reconstr Surg 2019 Feb;143(2):654

J Craniofac Surg 2019 Jan 19. Epub 2019 Jan 19.

Division of Plastic Surgery, Baylor College of Medicine; Houston, TX.

Multiple or large distance mandibular distraction osteogenesis (MDO) in the older child is often complicated by iatrogenic temporomandibular joint (TMJ) pathology. The transmission of significant force to the TMJ in these particular patients is due to the greater distance of distraction required and the relative inelasticity of the soft tissue envelope. The authors present a clinical report of a successful asymmetrically vectored large distance MDO in a 13-year-old female with bilateral craniofacial microsomia with Goldenhar syndrome. Read More

J Craniomaxillofac Surg 2019 Feb 7;47(2):219-227. Epub 2018 Dec 7.

Stomatology Department, São José Hospital, R. José António Serrano, Lisbon Portugal.

Background: Transport distraction osteogenesis is challenged as a potential alternative to free-flap reconstruction of segmental jaw defects due to its longer treatment time, vector control difficulties, need for additional bone-grafting, and problems creating a curvilinear shape. We propose a new technique of acute open callus manipulation and fixation (AOCMF), which addresses these challenges.

Methods: A retrospective analysis of all patients with jaw defects who underwent DO and AOCMF between 2006 and 2015 was performed. Read More

J Craniomaxillofac Surg 2019 Feb 6;47(2):204-218. Epub 2018 Dec 6.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, China; Medical Device College, Shanghai University of Medicine and Health Sciences, No. 257, Zhouzhu Highway, Pudong District, Shanghai, China; Department of Plastic and Reconstructive Surgery, Maternal and Child Health Care Hospital of Hainan Province, Haikou 570206, China. Electronic address:

Background: Distraction osteogenesis can be used to treat hemifacial microsomia in patients of any age group. Application of three-dimensional (3D) technology in the surgical planning of distraction osteogenesis allows the placement of an intraoral distractor to define the cutting line and help predict the outcome of surgery.

Aim: This study compared the results of distraction osteogenesis performed, using computer-assisted surgery, on OMENS-plus-classified M2A, M2B, and M3 type patients. Read More

J Craniofac Surg 2019 Jan;30(1):39-46

Department of Plastic, Reconstructive and Aesthetic Surgery, Tokyo Metropolitan Police Hospital.

Severe facial asymmetry in adults with hemifacial microsomia or other types of mandibular hypoplasia is challenging to treat with simultaneous maxillomandibular distraction osteogenesis using an external distractor combined with intermaxillary fixation (IMF). Using an external distractor also produces significant distress for patients for at least 8 weeks. Furthermore, mandibular-driven distraction tends to elongate the midface, with difficulty positioning of the center of the maxilla in the center of the face and horizontalization of the occlusal plane. Read More

J Craniofac Surg 2019 Jan;30(1):e80-e85

Department of Pathology, Faculty of Medicine, University of Necmettin Erbakan, Konya, Turkey.

Introduction: Mandibular distraction osteogenesis (DO) is frequently used in the management of bone defects and craniofacial deformities, with analgesics commonly administered to relieve acute postoperative pain. This experimental animal study investigated the effects of 2 analgesics, acetaminophen and acemetacin, on bone regeneration after DO.

Materials And Methods: This study was conducted with 14 mature male New Zealand rabbits (2. Read More

Maxillofac Plast Reconstr Surg 2018 Dec 15;40(1):32. Epub 2018 Nov 15.

1Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Tissue Regeneration and Reconstruction, Course for Oral Life Science, Niigata University Graduate School of Medical and Dental Sciences, 2-5274, Gakkocho-Dori, Chuo-Ku, Niigata, 951-8514 Japan.

Background: The free vascularized fibula flap presents many advantages such as sufficient length of the bony segment, good vascularization, better quality of the bone, and a long vascular pedicle, but it is also associated with some disadvantages with regard to prosthetic rehabilitation because of its limited height. Improvement in bone height is necessary for ideal dental implant treatment of reconstructed mandibles.

Case Presentation: For two squamous cell carcinoma patients, mandibular bone reconstruction was performed secondarily with the peroneal flap after tumor resection. Read More

J Stomatol Oral Maxillofac Surg 2018 Dec 1. Epub 2018 Dec 1.

Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Center, Moradabad, UP, India. Electronic address:

Objectives: The purpose of this study is to evaluate the role of primary osteo-distraction prior to ankylosis release in patients, diagnosed with sleep apnoea, facial asymmetry, and reduced quality of life secondary to temporomandibular joint (TMJ) ankylosis.

Methods: Ten patients in the age group of 13-40 years with TMJ ankylosis underwent primary osteo-distraction for mandibular advancement. They were evaluated pre- and post-operatively using radiographs, various questionnaires, and subjective evaluation of facial asymmetry, sleep apnoea, and quality of life (QOL). Read More

Plast Reconstr Surg 2018 11;142(5):1294-1298

New Haven, Conn. From Plastic and Reconstructive Surgery, Craniomaxillofacial Surgery, Yale School of Medicine.

Plast Reconstr Surg 2018 11;142(5):1285-1293

Philadelphia, Pa. From the Division of Plastic Surgery, Children's Hospital of Philadelphia.

Background: Controversy exists regarding the treatment of mandibular hypoplasia in craniofacial microsomia patients, notably the role of mandibular distraction osteogenesis. The authors compared the need for orthognathic surgery in skeletally mature craniofacial microsomia subjects who either did (study group) or did not (control group) undergo early mandibular distraction osteogenesis.

Methods: A retrospective review was conducted of all craniofacial microsomia patients evaluated between January of 1993 and March of 2017. Read More

J Oral Maxillofac Res 2018 Jul-Sep;9(3):e1. Epub 2018 Sep 30.

Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, AalborgDenmark.

Objectives: The objective of the present systematic review was to assess the transverse skeletal and dental arch expansion and relapse after mandibular midline distraction osteogenesis with a bone-borne, tooth-borne or hybrid distraction appliance.

Material And Methods: A MEDLINE (PubMed), Embase and Cochrane library search in combination with a hand-search of relevant journals was conducted. Human studies published in English until the 3 of July, 2018 were included. Read More

J Stomatol Oral Maxillofac Surg 2018 Nov 2. Epub 2018 Nov 2.

Service d'O.R.L, chirurgie orale et maxillo-faciale, Pr J. Santini and Pr L. Castillo, institut universitaire de la face et du cou (IUFC), CHU de Pasteur, 31, avenue de Valombrose, 06100 Nice. France.

Orthognathic surgical technique of segmental osteogenesis distraction of the anterior mandible alveolar process (front-block) was introduced by Triaca and al. in 2001 [2] including lower incisors. The technical note describes distraction process used both, dental-borne distractor and bone-borne distractor. Read More

Medicine (Baltimore) 2018 Oct;97(42):e12853

Department of Plastic Surgery, Children's Hospital Colorado, Aurora, CO.

Rationale: There is a high prevalence of obstructive sleep apnea (OSA) in patients with Pierre Robin sequence (PRS), and treatment approaches are highly variable. One approach is a temporary tongue-lip adhesion (TLA) that acts as a temporizing measure while the mandible continues to grow and is usually taken down at 1 year of age.

Patient Concerns: Side effects of prolonged tongue-lip adhesion and optimal workup and treatment of persistent OSA in the setting of a tongue-lip adhesion. Read More

Br J Oral Maxillofac Surg 2018 11 4;56(9):814-819. Epub 2018 Oct 4.

Department of Oral and Craniomaxillofacial Surgery, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai, China. Electronic address:

We have assessed the accuracy and clinical validation of virtual planning using a surgical template in 16 patients with hemifacial microsomia being treated by mandibular distraction osteogenesis. Virtual planning and simulation were first done on three-dimensional models. Distraction was simulated on the virtual model and the new morphology of the mandible was previewed. Read More

Braz Oral Res 2018 Sep 21;32:e85. Epub 2018 Sep 21.

Firat University, Faculty of Dentistry, Department of Periodontology, Elazig, Turkey.

This study aimed to investigate the effects of different doses of systemic melatonin application on new bone formation during mandibular distraction osteogenesis (DO) in rats. Mandibular DO was performed on 30 adult female Sprague-Dawley rats, which were randomly divided into three groups: control group (CNT), melatonin dose 1 (MLT-D1), and melatonin dose 2 (MLT-D2). A five-day latent waiting period and a ten-day distraction phase followed the surgery. Read More

Orthod Fr 2018 09 26;89(3):279-288. Epub 2018 Sep 26.

Faculté d'Odontologie,rue Guillaume Paradin 69372 Lyon cedex 08, France.

Introduction: The aim of this systematic literature review is to propose a clinical protocol in 2018 by comparing therapeutic efficacy and undesirable effects of the technique.

Materials And Methods: Searches were made on Pubmed/Medline and Cochrane for randomized clinical trials and case series involving mandibular symphyseal distraction over the past 20 years with a patient sample greater than or equal to 10.

Results: Of the 92 articles, 25 met the inclusion criteria. Read More

Orthod Fr 2018 09 26;89(3):259-277. Epub 2018 Sep 26.

Faculté d'Odontologie, rue Guillaume Paradin, 69372 Lyon cedex 08, France.

Introduction: The purpose of this systematic literature review is to evaluate the benefit / risk ratio of mandibular symphyseal distraction osteogenesis.

Materials And Methods: Searches were made on Pubmed/Medline and Cochrane for randomized clinical trials and case series involving mandibular symphyseal distraction over the past 20 years with a patient sample greater than or equal to 10.

Results: Of the 92 articles, 25 met the inclusion criteria. Read More

Oral Maxillofac Surg 2018 Dec 25;22(4):409-418. Epub 2018 Sep 25.

Department of Oral and Maxillofacial Surgery, Nair Hospital Dental College, Room no 107, A L Nair Road, Mumbai, Maharashtra, 400008, India.

Introduction: In severe TMJ ankylosis cases, the lack of growth of the mandible creates an anatomically narrow airway with a reduced pharyngeal airway space [PAS] which predisposes these patients towards obstructive apnoea [OSA]. There is evidence in the literature that such patients experience severe discomfort during physiotherapy if such airway abnormalities are not corrected prior to ankylosis release. This eventually leads to non-compliance towards physiotherapy and increases the risk of re-ankylosis. Read More

Plast Reconstr Surg 2018 10;142(4):1009-1010

Houston, Texas From the Division of Plastic Surgery, Texas Children's Hospital and Baylor College of Medicine.

J Craniomaxillofac Surg 2018 Nov 31;46(11):1883-1892. Epub 2018 Aug 31.

Department of Oral and Maxillofacial Surgery, (Head: Eppo B. Wolvius, DMD, MD, PhD), Erasmus MC, University Medical Center Rotterdam, the Netherlands.

Objective: To provide a literature overview on mandibular midline distraction (MMD) using three-dimensional (3D) imaging analysis techniques. Regarding different distractor types, the focus was on changes in position and/or morphology of the mandibular condyle and temporomandibular joint (TMJ), skeletal effects, dental effects, soft tissue effects, and biomechanical and masticatory effects, specifically on the mandible and TMJ.

Methods: Studies up to March 27 2017 were included, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines, using Embase, Medline OvidSP, Web-of-science, Scopus, Cochrane, and Google Scholar. Read More

Plast Reconstr Surg 2018 12;142(6):1501-1509

Haifa and Tel-Aviv, Israel From the Departments of Oral and Maxillofacial Surgery and Orthodontics and Craniofacial Anomalies, Rambam Health Care Campus; the Ruth & Bruce Rappaport Faculty of Medicine at the Technion-Israel Institute of Technology; and the Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel-Aviv University.

Background: Distraction osteogenesis has widespread clinical use in the treatment of congenital and acquired craniofacial deformities. Nonetheless, during the prolonged consolidation period, the newly regenerated bone carries the risk of complications. A known method for enhancing bone healing is extracorporeal shock wave therapy, which has been shown to induce neovascularization and promote tissue regeneration. Read More

Am J Orthod Dentofacial Orthop 2018 Sep;154(3):421-432

Department of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China. Electronic address:

This case report describes the nonsurgical treatment of an adolescent patient with a severe transverse discrepancy presented as a Brodie bite and retrognathic mandible. Distraction osteogenesis has been often used for similar cases in the literature. However, in this patient, a fixed appliance with 1 maxillary extraction combined with a functional appliance was used to resolve the transverse discrepancy with natural growth. Read More

J Coll Physicians Surg Pak 2018 Sep;28(9):S184-S186

Department of Oral and Maxillofacial Surgery, Army Medical College, Rawalpindi, Pakistan.

Obstructive sleep apnea syndrome (OSAS), commonly associated with mandibular micrognathia, is a serious condition that can lead to various devastating cardiovascular and neurocognitive consequences. Patients of OSAS with micrognathia present with many functional and esthetic problems. Therefore, comprehensive management of these patients requires multiple surgeries and frequent follow-up. Read More

J Oral Maxillofac Surg 2018 Nov 7;76(11):2422.e1-2422.e20. Epub 2018 Aug 7.

Professor, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan, China. Electronic address:

Purpose: This study evaluated the accuracy of virtual surgical planning and 3-dimensional (3D) printed templates to guide osteotomy and distraction osteogenesis (DO) in the treatment of temporomandibular joint (TMJ) ankylosis and secondary mandibular deformity.

Patients And Methods: Seven consecutive patients diagnosed with TMJ ankylosis and mandibular deformities were included. A composite skull model was obtained with data from spiral computed tomography (CT) and laser scanning of the dental arch. Read More

Plast Reconstr Surg 2018 08;142(2):458-462

New Haven, Conn. From Plastic and Reconstructive Surgery, Craniomaxillofacial Surgery, Yale School of Medicine.

Plast Reconstr Surg 2018 10;142(4):1002-1008

Beijing, People's Republic of China From the Department of Maxillofacial Surgery, Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences, Peking Union Medical College.

Background: This study focused mainly on the safety and unexpected incidents of mandibular distraction osteogenesis in treating patients with hemifacial microsomia.

Methods: Records of 71 patients with hemifacial microsomia treated by mandibular distraction osteogenesis from February of 2010 to March of 2015 were examined in this retrospective study. The modified mandibular osteotomy was conducted under the assistance of three-dimensional reconstruction, computer-aided design, and rapid prototyping technique. Read More

J Craniomaxillofac Surg 2018 Sep 24;46(9):1436-1440. Epub 2018 May 24.

The Dutch Craniofacial Centre, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Center (Head of Department: Professor Eppo B. Wolvius), Sophia's Children's Hospital, Rotterdam, The Netherlands; Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, USA; Craniofacial Unit, Great Ormond Street Hospital, London, United Kingdom.

Introduction: Patients with Craniofacial Microsomia (CFM) mandibles Types I/IIa benefit from combined LeFort 1 osteotomy and Mandibular Distraction Osteogenesis (LeFort + MDO); Type IIb from LeFort + MDO or Bimaxillary osteotomy (BiMax); and Type III from BiMax (with 50% of cases having preceding mandibular procedures, including patient-fitted prosthesis); as seen in Part 1. This leads to the question how maxillary and mandibular hypoplasia are correlated and influence the types of maxillary correction.

Material And Methods: A retrospective chart study was conducted including patients diagnosed with CFM from 2 large craniofacial units. Read More

Ann Plast Surg 2018 Sep;81(3):305-310

From the Hansjörg Wyss Department of Plastic Surgery, NYU Langone Medical Center, New York, NY.

Introduction: Treacher Collins syndrome (TC) and Pierre Robin sequence (RS) are associated with hypoplastic mandible, glossoptosis, and consequent airway obstruction. Although TC and RS are often grouped together, airway outcomes of bilateral mandibular distraction osteogenesis (MDO) have not been specifically studied in TC. The purpose of this study is to report on the clinical outcomes of MDO in the TC patient population. Read More

Plast Reconstr Surg 2018 08;142(2):480-509

Philadelphia, Pa. From the Division of Plastic Surgery, Children's Hospital of Philadelphia.

There is a paucity of literature directly comparing tongue-lip adhesion versus mandibular distraction osteogenesis in surgical treatment of patients with Pierre Robin sequence. This study comprehensively reviews the literature for evaluating airway and feeding outcomes following mandibular distraction osteogenesis and tongue-lip adhesion. A search was performed using the MEDLINE and Embase databases for publications between 1960 and June of 2017. Read More

Plast Reconstr Surg 2018 08;142(2):447-457

Seattle, Wash. From the Division of Plastic Surgery and the Department of Otolaryngology, University of Washington; and the Craniofacial Center, Seattle Children's Hospital.

Background: The craniofacial rotation deformity in Treacher Collins syndrome results in airway compression that is not addressed by isolated mandibular distraction osteogenesis. Our purpose is to present a surgical technique-counterclockwise craniofacial distraction osteogenesis-that improves airway morphology and occlusal rotation in tracheostomy-dependent patients with this condition.

Methods: All patients underwent subcranial Le Fort II osteotomies with simultaneous mandibular osteotomies, followed by coordinated maxillomandibular distraction with counterclockwise rotation. Read More

J Craniofac Surg 2018 Oct;29(7):1851-1854

Guangzhou Women and Children's Medical Center, Guangzhou City, China.

Mandibular distraction osteogenesis (MDO) effectively improves airway obstruction in Pierre Robin syndrome (PRS) patients. However, whether or not early MDO is beneficial to the development of children is still controversial. To observe the influence of PRS patient age at the time of MDO on their development, the authors retrospectively analyzed preoperative and postoperative body weight in 41 children with PRS who underwent MDO treatment from 2014 to 2016. Read More

J Craniomaxillofac Surg 2018 Aug 18;46(8):1343-1347. Epub 2018 May 18.

Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2400, 90035-003, Porto Alegre, RS, Brazil; Pediatric Pulmonology Unit, HCPA, Rua Ramiro Barcelos, 2350, 90035-903, Porto Alegre, RS, Brazil. Electronic address:

Introduction: The optimal surgical technique for the management of patients with Robin Sequence (RS) has not been established. One of the most commonly used surgical techniques, mandibular distraction osteogenesis (MDO), is still controversial because of its potential risks and the lack of clear evidence of its efficacy.

Objectives: To assess variations in airway patency, clinical symptoms, and polysomnographic parameters in children with RS who underwent MDO. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 May;32(5):558-567

Department of Orthopedics, Changzheng Hospital, the Second Military Medical University, Shanghai, 200003,

Objective: To investigate the effect, right timing, and mechanism of "accordion" technique on bone regeneration in rat distraction osteogenesis model.

Methods: Fifty-four 12-week-old male Sprague Dawley rats underwent right tibial distraction osteogenesis procedure. After a 5-day latency, the distraction was performed for 7 days followed by 6-week consolidation. Read More

J Craniofac Surg 2018 Sep;29(6):1629-1632

Department of Oral and Maxillofacial Surgery, Daejeon Dental Hospital, College of Dentistry, Wonkwang University, Daejeon.

Distraction osteogenesis a surgical procedure conducted to improve craniofacial deformities. Compared with conventional operations, this technique has advantages such as the ability to lengthen the soft tissue and hard tissue. Therefore, this method is used to treat severe craniofacial abnormalities. Read More

J Craniofac Surg 2018 Sep;29(6):1666-1670

Department of Orthodontics, Faculty of Dentistry, Ondokuz Mayis University, Samsun, Turkey.

Objective: Distraction osteogenesis (DO) is widely used treatment for the bone deformities. In addition extracorporeal shock wave therapy (ESWT) is a new perspective on noninvasive modalities of management of the bone regeneration. We examined the effects of 2 different single doses of ESWT on the consolidation period of DO of the rabbit mandible using stereological, radiological and immunohistochemical methods in the present study. Read More

Aust Dent J 2018 Mar;63 Suppl 1:S100-S107

Melbourne Oral & Maxillofacial Surgeon, Melbourne, Victoria, Australia.

The atrophic and edentulous jaw can pose a number of challenges for the implant clinician. In simple terms, the amount of bone that remains is insufficient for the conventional placement of a dental implant. A variety of treatment strategies can be employed to enable implants to be placed despite the paucity of bone stock in either the mandible or the maxilla. Read More

Neural Regen Res 2018 Feb;13(2):360-365

Department of Oral & Maxillofacial-Head & Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology; National Clinical Research Center of Stomatology, Shanghai; Department of Oral Surgery, State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi Province, China.

Distraction osteogenesis is an important technique for the treatment of maxillofacial abnormities and defects. However, distraction osteogenesis may cause the injury of the inferior alveolar nerve. The relationship between distraction rate and nerve degeneration-regeneration shift remains poorly understood. Read More

J Craniofac Surg 2018 Jul;29(5):1187-1192

Department of Otolaryngology - Head and Neck Surgery, Northwestern University Feinberg School of Medicine.

Purpose: Airway management in neonates with Pierre Robin sequence (PRS) can be challenging. The goal was to describe the algorithm developed by the authors over the past 8 years.

Methods: A retrospective case series analyzing airway management in neonates with PRS admitted to the neonatal intensive care unit at a tertiary care pediatric hospital was performed. Read More

J Craniofac Surg 2018 May;29(3):676-682

Section of Plastic Surgery, Yale University School of Medicine, New Haven, CT.

Mandibular distraction osteogenesis (MDO) is an effective treatment modality for children suffering from upper airway obstruction from Robin Sequence (RS). Mandibular distraction osteogenesis has been shown to have positive effects on oral feeding and for relieving respiratory obstruction, but its effects on postoperative weight gain are poorly understood. This study quantitatively analyzes weight gain following MDO. Read More

J Craniofac Surg 2018 Mar;29(2):427-431

Department of Oral and Maxillofacial Surgery, Universidad de la Frontera, Temuco, Chile.

: Temporomandibular joint ankylosis, according to age of onset, causes severe functional and morphological disorders, as well as stunted craniofacial growth and development.The primary goal of treatment is to resolve the functional and morphological disorders.

Method: Pre- and posttreatment clinical and cephalometric registries were conducted in 15 patients with temporomandibular joint ankylosis over a 10-year period (2002-2012). Read More

J Oral Maxillofac Surg 2018 Jul 31;76(7):1512-1523. Epub 2018 Jan 31.

Walter C. Guralnick Distinguished Professor and Chief, Emeritus, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA.

Purpose: 1) To assess the fate of the permanent teeth in and adjacent to the regenerate in pediatric patients who underwent mandibular distraction osteogenesis (DO) and 2) to compare the postoperative growth of the distracted mandible with age- and gender-matched controls.

Patients And Methods: This was a retrospective cohort study of children who underwent mandibular DO during the primary or mixed dentition period and before completion of somatic growth (boys aged ≤14 years and girls aged ≤12 years) at Massachusetts General Hospital from 1996 to 2014. From the DO registry, patients were selected who had complete clinical and radiographic records and at least 1 year of follow-up. Read More

J Craniofac Surg 2018 Jun;29(4):970-972

Department of Orthodontics, Vita Salute, San Raffaele University.

Distraction osteogenesis (DO) is a technique that allows the generation of new bone in a gap between 2 vascularized bone surfaces in response to the application of graduated tensile stress across the bone gap.Distraction osteogenesis has become a routine treatment of choice to correct skeletal deformities and severe bone defects in the craniofacial complex over the past decade. Distraction osteogenesis has been successfully chosen in lengthening the maxilla and the mandible; in the maxilla and recently in the mandible, the jawbones have been distracted and widened transversely to relieve severe anterior dental crowding and transverse discrepancies between the dental arches. Read More

J Craniofac Surg 2018 Mar;29(2):e184-e190

The Craniofacial Center One, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Interpositional arthroplasty (IPA) with temporalis fascia flap has been one of the most frequently performed procedures to treat temporomandibular joint (TMJ) ankylosis. However, recurrence often occurs when the flap lacks bulk or atrophies. Whether to perform IPA or distraction osteogenesis (DO) first has long been a controversial issue when patients presented mandibular dysplasia (MD). Read More

J Oral Maxillofac Surg 2018 Apr 29;76(4):752-760. Epub 2017 Nov 29.

Nobel Biocare Endowed Chair, School of Dentistry, University of California-Los Angeles, Los Angeles, CA.

Purpose: The aim of this study was to assess the clinical effectiveness of alveolar distraction osteogenesis (ADO) versus recombinant human bone morphogenetic protein-2 (rh-BMP-2) for vertical ridge augmentation. Few data have been published on vertical bone regeneration using rh-BMP-2.

Materials And Methods: The authors implemented a retrospective cohort study and enrolled a sample composed of patients with deficient alveolar vertical bone height. Read More

Plast Reconstr Surg 2018 04;141(4):1003-1009

Chicago, Ill.; and Fort Lauderdale, Fla. From the Department of Surgery, Section of Plastic Surgery, the Department of Radiology, and the Department of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago Medical Center; the University of Chicago Pritzker School of Medicine; and the Atlantic Center of Aesthetic and Reconstructive Surgery.

Background: The authors investigated the accuracy of virtual surgical planning in predicting airway volume changes after mandibular distraction in patients with Pierre Robin sequence and associated tongue-based airway obstruction.

Methods: The authors completed a single-institution retrospective review of patients for whom virtual surgical planning was used during mandibular distraction osteogenesis for treatment of tongue-based airway obstruction. Preoperative airway volume, virtual surgical planning-predicted airway volume, and postoperative airway volume were calculated from three-dimensional computed tomographic scans using industry software. Read More

J Craniofac Surg 2018 Mar;29(2):e111-e116

Government Dental Center, Pune.

Distraction osteogenesis has been a paradigm shift in the field of orthognathic surgery. Majority of the published cases are those of syndromic patients that have been managed using varying treatment protocols. This communication describes a patient of 18-year-old male diagnosed with skeletal Class II malocclusion due to mandibular retognathism. Read More

Int J Oral Maxillofac Surg 2018 Mar 14;47(3):357-365. Epub 2017 Nov 14.

Department of Oral and Maxillofacial Surgery, Dentistry and Orthodontics, University of Tokyo Hospital, Tokyo, Japan.

Maxillary distraction is increasingly used for the correction of severe maxillary retrusion in patients with cleft lip and palate. However, control of the maxillary movement is difficult, and the need to wear visible distractors for a long period of time causes psychosocial problems. A two-stage surgical approach consisting of maxillary distraction and mandibular setback was developed to overcome these problems. Read More

Head Face Med 2017 Nov 10;13(1):20. Epub 2017 Nov 10.

Department of Orthodontics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Background: We describe the case of a 16-year-old female patient with micrognathia, temporomandibular joint (TMJ) ankylosis, and obstructive sleep apnea, who was treated with mandibular distraction osteogenesis (DO) combined with sliding genioplasty, using skeletal anchorage.

Case Presentation: We first performed interpositional arthroplasty, in which an interposition of fascia temporalis and surrounding fat tissue was inserted into the defect after bilateral condylectomy, increasing the maximum mouth opening from 5.0 to 32. Read More