5,557 results match your criteria Dissociative Disorders


Psychogenic Non-epileptic Seizures and Pseudo-Refractory Epilepsy, a Management Challenge.

Front Neurol 2020 2;11:461. Epub 2020 Jun 2.

Department of Neuroscience, Imaging and Clinical Science, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Psychogenic nonepileptic seizures (PNES) are neurobehavioral conditions positioned in a gray zone, not infrequently a no-man land, that lies in the intersection between Neurology and Psychiatry. According to the DSM 5, PNES are a subgroup of conversion disorders (CD), while the ICD 10 classifies PNES as dissociative disorders. The incidence of PNES is estimated to be in the range of 1. Read More

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http://dx.doi.org/10.3389/fneur.2020.00461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280483PMC

Proof of Concept of an Eclectic, Integrative Therapeutic Approach to Mental Health and Well-Being Through Virtual Reality Technology.

Front Psychol 2020 5;11:858. Epub 2020 Jun 5.

Canadian Armed Forces, Ottawa, ON, Canada.

Across three studies, we provide a proof-of-concept evaluation of an integrative psychotherapeutic application of virtual reality (VR) technology. Study 1 ( = 36) evaluated an unguided "safe-place" imagery task, where participants were instructed "to create a safe space… [such as] a scene, item, design, or any visual representation that makes you feel safe" using either the Google Tilt Brush application (VR condition), the standard Microsoft Paint application (2-D condition), or via eyes-closed mental imagery alone (IMG condition). Study 2 ( = 48) evaluated a narrative episodic recall task, where participants viewed their childhood and adult homes and places of schooling either using either the Google Earth VR application (VR condition) or the standard Google Earth application (2-D condition) or recalled these places with their eyes closed via mental imagery alone (IMG condition). Read More

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http://dx.doi.org/10.3389/fpsyg.2020.00858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290015PMC

[Background and psychological impact of organised and ritual child sexual abuse: Reports to the Independent Inquiry into Child Sexual Abuse in Germany].

Fortschr Neurol Psychiatr 2020 Jun 18;88(6):374-378. Epub 2020 Jun 18.

Institut für Sexualforschung, Sexualmedizin und Forensische Psychiatrie, Universitätsklinikum Hamburg-Eppendorf.

Objective: Organised child sexual abuse is characterised by commercial exploitation of children and adolescents by networking perpetrator groups. Ritual abuse is further characterised by ideological frameworks (e.g. Read More

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http://dx.doi.org/10.1055/a-1149-2103DOI Listing

Use of Mixed Amphetamine Salts in a Patient with Depersonalization/Derealization Disorder.

Authors:
Samuel R Weber

Innov Clin Neurosci 2020 Jan;17(1-3):45-48

Dr. Weber is with Intermountain Healthcare in Logan, Utah.

Depersonalization and derealization symptoms are common and often transient. Recurrent, persistent symptoms can result in a diagnosis of depersonalization/derealization disorder (DDD). This is a diagnosis with little evidence available regarding effective interventions, and there are currently no pharmacological treatments for DDD approved by the United States Food and Drug Administration (FDA). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239558PMC
January 2020

[Childhood adverse traumatic experiences and schizophrenia].

Psychiatriki 2020 Jan-Mar;31(1):23-35

1st Psychiatric Department, University of Athens, Eginition Hospital, Athens, Greece.

Εpidemiological research during last decades has demonstrated the association of certain environmental variables with psychosis. Ιn parallel with understanding environmental contributors to schizophrenia, identification of those at high risk of psychosis has become a priority. These risk factors include adverse traumatic experiences, such as discrimination, social environment adversities, bullying, emigration and childhood trauma. Read More

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http://dx.doi.org/10.22365/jpsych.2020.311.23DOI Listing

Sudden Complex Hallucinations in a 14-Year-Old Girl: Schizophrenia Spectrum Disorders Versus Dissociative Disorders-The Influence of Early Life Experiences on Future Mental Health.

J Dev Behav Pediatr 2020 Jun 10. Epub 2020 Jun 10.

INCLIVA Biomedical Research Group, Valencia, Spain.

Case: A 14-year-old girl is taken to the pediatric emergency department (ED) by her parents because of sudden complex hallucinations.She shows moderate intellectual disability without a peculiar phenotype already evaluated by neuropediatrics (normal comparative genomic hybridization array and brain magnetic resonance imaging) and most likely related to affective deprivation at the orphanage. Adopted at 20 months from China, her parents reported that on arrival she had scars, allegedly from being tied to a chair for a long time, and that although she was able to stand, she could not walk. Read More

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http://dx.doi.org/10.1097/DBP.0000000000000829DOI Listing

Safety and tolerability of IV ketamine in adults with major depressive or bipolar disorder: results from the Canadian rapid treatment center of excellence.

Expert Opin Drug Saf 2020 Jun 15:1-10. Epub 2020 Jun 15.

Mood Disorders Psychopharmacology Unit, University Health Network; University of Toronto , Toronto, ON, Canada.

Objectives: Rigorous clinical trials suggest ketamine is safe and well-tolerated in patients with treatment-resistant depression (TRD). There is a paucity of data on the safety and tolerability of ketamine in community-based clinics treating patients with TRD.

Methods: Retrospective data was analyzed from 203 patients with TRD who received repeat-dose IV ketamine. Read More

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http://dx.doi.org/10.1080/14740338.2020.1776699DOI Listing
June 2020
2.911 Impact Factor

Pediatric Psychiatric Emergencies at a Tertiary Care Center in India.

Indian Pediatr 2020 Jun 12. Epub 2020 Jun 12.

Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India. Correspondence to: Dr Raman Deep, Additional Professor, Department of Psychiatry, All India Institute of Medical Sciences, New Delhi 110 029, India.

Objectives: To describe the clinical profile and pattern of pediatric psychiatry emergency referrals at a tertiary-care center in India.

Methods: Retrospective chart review of emergency psychiatry records over a 13-month period (January 2015 - January 2016).

Results: Pediatric psychiatric emergencies (n=65) (mean (SD) age, 14. Read More

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Charcot in the ICU: functional tetraplegia after surgery.

Pract Neurol 2020 Jun 12. Epub 2020 Jun 12.

Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Functional neurological disorder is a condition in which a patient has physical findings that are not compatible with anatomical boundaries, have no structural substrate and are not representable of an established disease. General anaesthesia and surgery have been previously reported as precipitating factors for functional disorders and mostly involve dissociative (non-epileptic) seizures. We report a patient with no psychiatric history or prior abnormal examination who developed sudden-onset functional tetraplegia and sensory disturbances immediately after elective surgery, and who was subsequently discharged home several days later after nearly complete resolution of neurologic deficits. Read More

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http://dx.doi.org/10.1136/practneurol-2020-002601DOI Listing

"Seat of the soul"? The structure and function of the pineal gland in women with alleged spirit possession-Results of two experimental studies.

Brain Behav 2020 Jun 7:e01693. Epub 2020 Jun 7.

School of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil.

Background: Cultural traditions attribute to pineal gland an important role for spiritual experiences. Mediumship and spirit possession are cultural phenomena found worldwide which have been described as having dissociative and psychotic-like characteristics, but with nonpathological aspects. A sympathetic activation pattern in response to spirit possession has been reported in some studies, but empirical data on pineal gland is scarce in this context. Read More

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http://dx.doi.org/10.1002/brb3.1693DOI Listing

The course of (comorbid) trauma-related, dissociative and personality disorders: two year follow up of the Friesland study cohort.

Eur J Psychotraumatol 2020 4;11(1):1750171. Epub 2020 May 4.

Amsterdam UMC, Vrije Universiteit, Psychiatry, Amsterdam Public Health, Amsterdam, The Netherlands.

: There is substantial comorbidity between trauma-related disorders (TRDs), dissociative disorders (DDs) and personality disorders (PDs), especially in patients who report childhood trauma and emotional neglect. However, little is known about the course of these comorbid disorders, despite the fact that this could be of great clinical importance in guiding treatment. : This study describes the two-year course of a cohort of patients with (comorbid) TRDs, DDs and PDs and aims to identify possible predictors of course. Read More

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http://dx.doi.org/10.1080/20008198.2020.1750171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241467PMC

Ketamine as a mental health treatment: Are acute psychoactive effects associated with outcomes? A systematic review.

Behav Brain Res 2020 May 30;392:112629. Epub 2020 May 30.

Clinical Psychopharmacology Unit, University College London, 1-19 Torrington Place, London WC1E 7HB, UK.

Esketamine was recently licensed by the US Food and Drug Administration (FDA) and European Drug Agency (EDA) for use in treatment resistant depression (TRD), and further research indicates ketamine as a possible treatment in other mental health conditions. While the underlying mechanisms remain unclear, it has been hypothesised that ketamine's acute psychoactive effects may be associated with psychiatric treatment efficacy. We systematically reviewed the evidence for this association. Read More

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http://dx.doi.org/10.1016/j.bbr.2020.112629DOI Listing

Dissociative Amnesia and Dissociative Fugue in a 20-Year-Old Woman With Schizoaffective Disorder and Post-Traumatic Stress Disorder.

Cureus 2020 May 26;12(5):e8289. Epub 2020 May 26.

Psychiatry, Riverview Medical Center, Red Bank, USA.

Dissociative amnesia is memory loss that cannot be explained by a neurological abnormality or typical forgetfulness. It belongs to the rare class of psychiatric ailments known as dissociative disorders. It can be accompanied with dissociative fugue where the individual travels or wanders away from home. Read More

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http://dx.doi.org/10.7759/cureus.8289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255065PMC

Structural and functional brain alterations in psychiatric patients with dissociative experiences: A systematic review of magnetic resonance imaging studies.

J Psychiatr Res 2020 May 13;128:5-15. Epub 2020 May 13.

Department of Clinical Psychology, University of Groningen, the Netherlands. Electronic address:

Introduction: There is currently no general agreement on how to best conceptualize dissociative symptoms and whether they share similar neural underpinnings across dissociative disorders. Neuroimaging data could help elucidate these questions.

Objectives: The objective of this review is to summarize empirical evidence for neural aberrations observed in patients suffering from dissociative symptoms. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2020.05.006DOI Listing

Stress, the brain, and trauma spectrum disorders.

Int Rev Neurobiol 2020 19;152:1-22. Epub 2020 Feb 19.

Emory University School of Medicine, Atlanta, GA, United States.

This chapter reviews the relationship between stress and brain function in patients with neuropsychiatric disorders, with an emphasis on disorders that have most clearly been linked to traumatic stress exposure. These disorders, which have been described as trauma spectrum disorders, include posttraumatic stress disorder (PTSD), a subgroup of major depression, borderline personality disorder (BPD) and dissociative disorders; they share in common a neurobiological footprint, including smaller hippocampal volume, and are distinguished from other disorders that may share symptom similarities, like some of the anxiety disorders, but are not as clearly linked to stress. The relationship between environmental events such as stressors, especially in early childhood, and their effects on brain and neurobiology is important to understand in approaching these disorders as well as the development of therapeutic interventions. Read More

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http://dx.doi.org/10.1016/bs.irn.2020.01.004DOI Listing
February 2020

Uptrend in distress and psychiatric symptomatology in pregnant women during the coronavirus disease 2019 pandemic.

Acta Obstet Gynecol Scand 2020 07 3;99(7):848-855. Epub 2020 Jun 3.

CERVO Brain Research Center, Quebec City, QC, Canada.

Introduction: Prenatal maternal distress has a negative impact on the course of pregnancy, fetal development, offspring development, and later psychopathologies. The study aimed to determine the extent to which the coronavirus disease 2019 (COVID-19) pandemic may aggravate the prenatal distress and psychiatric symptomatology of pregnant women.

Material And Methods: Two cohorts of pregnant volunteer women were evaluated, one that was recruited before the COVID-19 pandemic (n = 496) through advertisements in prenatal clinics in Quebec, Canada, from April 2018 to March 2020; the other (n = 1258) was recruited online during the pandemic from 2 April to 13 April 2020. Read More

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http://dx.doi.org/10.1111/aogs.13925DOI Listing

Classifying heterogeneous presentations of PTSD via the default mode, central executive, and salience networks with machine learning.

Neuroimage Clin 2020 Apr 22;27:102262. Epub 2020 Apr 22.

Department of Psychiatry, Western University, London, ON, Canada; Department of Neuroscience, Western University, London, ON, Canada; Imaging Division, Lawson Health Research Institute, London, ON, Canada.

Intrinsic connectivity networks (ICNs), including the default mode network (DMN), the central executive network (CEN), and the salience network (SN) have been shown to be aberrant in patients with posttraumatic stress disorder (PTSD). The purpose of the current study was to a) compare ICN functional connectivity between PTSD, dissociative subtype PTSD (PTSD+DS) and healthy individuals; and b) to examine the use of multivariate machine learning algorithms in classifying PTSD, PTSD+DS, and healthy individuals based on ICN functional activation. Our neuroimaging dataset consisted of resting-state fMRI scans from 186 participants [PTSD (n = 81); PTSD + DS (n = 49); and healthy controls (n = 56)]. Read More

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http://dx.doi.org/10.1016/j.nicl.2020.102262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240193PMC

Cognitive behavioural therapy for adults with dissociative seizures (CODES): a pragmatic, multicentre, randomised controlled trial.

Lancet Psychiatry 2020 06 20;7(6):491-505. Epub 2020 May 20.

Department of Psychological Medicine, King's College London, London, UK.

Background: Dissociative seizures are paroxysmal events resembling epilepsy or syncope with characteristic features that allow them to be distinguished from other medical conditions. We aimed to compare the effectiveness of cognitive behavioural therapy (CBT) plus standardised medical care with standardised medical care alone for the reduction of dissociative seizure frequency.

Methods: In this pragmatic, parallel-arm, multicentre randomised controlled trial, we initially recruited participants at 27 neurology or epilepsy services in England, Scotland, and Wales. Read More

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http://dx.doi.org/10.1016/S2215-0366(20)30128-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242906PMC

The CODES trial for dissociative seizures: a landmark study and inflection point.

Authors:
David L Perez

Lancet Psychiatry 2020 06 20;7(6):464-465. Epub 2020 May 20.

Departments of Neurology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(20)30143-7DOI Listing

Exploring the relationship between auditory hallucinations, trauma and dissociation.

BJPsych Open 2020 May 20;6(3):e54. Epub 2020 May 20.

School of Psychological Sciences, University of Western Australia, Perth; and Clinical Research Centre, Graylands Campus, North Metropolitan Health Service, Mental Health, Perth, Australia.

Background: It is clinically imperative to better understand the relationship between trauma, auditory hallucinations and dissociation. The personal narrative of trauma has enormous significance for each individual and is also important for the clinician, who must use this information to decide on a diagnosis and treatment approach.

Aims: To better understand whether dissociation contributes in a significant way to hallucinations in individuals with and without trauma histories. Read More

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http://dx.doi.org/10.1192/bjo.2020.31DOI Listing

Impact of dissociation on the effectiveness of psychotherapy for post-traumatic stress disorder: meta-analysis.

BJPsych Open 2020 May 19;6(3):e53. Epub 2020 May 19.

PSYTREC, Bilthoven; and Radboud University, Behavioural Science Institute, the Netherlands.

Background: Many patients with post-traumatic stress disorder (PTSD) experience dissociative symptoms. The question of whether these dissociative symptoms negatively influence the effectiveness of psychotherapy for PTSD is unresolved.

Aims: To determine the influence of dissociative symptoms on psychotherapy outcome in PTSD. Read More

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http://dx.doi.org/10.1192/bjo.2020.30DOI Listing

A Web-based Psychoeducation Program for People with Pathological Dissociation: Development and Pilot Testing.

J Evid Based Soc Work (2019) 2020 Apr 29:1-16. Epub 2020 Apr 29.

The Colin A. Ross Institute for Psychological Trauma, Richardson, Texas, USA.

: Although people with pathological dissociation (PD) can benefit from specific interventions, there are challenges in providing suitable interventions for them in the field (e.g., high cost, lack of specialized services, stigma). Read More

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http://dx.doi.org/10.1080/26408066.2020.1760990DOI Listing

Outcomes of a 5-week individualised MDT outpatient (day-patient) treatment programme for functional neurological symptom disorder (FNSD).

J Neurol 2020 May 14. Epub 2020 May 14.

Department of Clinical and Movement Neurosciences, National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, Queen Square, Box 95, London, WC1N 3BG, UK.

Aim: We report results from a 5-week MDT treatment programme, with individualised sessions, for a selected group of patients with FNSD, delivered in a neuropsychiatric outpatient setting. Primary aims were to (1) reduce symptoms, (2) improve functional performance and (3) improve health status.

Methods: Treatment involved individual sessions of neuropsychiatry, cognitive behavioural therapy, physiotherapy, occupational-therapy, education and family meetings. Read More

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http://dx.doi.org/10.1007/s00415-020-09874-5DOI Listing

Dissociative Symptoms In Posttraumatic Stress Disorder: A Systematic Review.

J Trauma Dissociation 2020 May 13:1-20. Epub 2020 May 13.

Department of Psychology, Florida State University, Tallahassee, FL, USA.

: Research on dissociative symptomatology in the context of Posttraumatic Stress Disorder (PTSD) has been gaining traction, with dissociation being studied as a set of complex symptoms following trauma exposure and as a specific subtype of PTSD. The aims of this review are to summarize the literature as it stands, examine the efficacy of existing interventions in treating dissociative symptomatology within the context of PTSD, and offer potential suggestions for future research.: A systematic approach was taken to locate empirical studies on PTSD that included dissociation as an outcome in the PubMed, Scopus, and PsycINFO databases. Read More

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http://dx.doi.org/10.1080/15299732.2020.1760410DOI Listing

A Preliminary Investigation of Depression in People with Pathological Dissociation.

J Trauma Dissociation 2020 May 13:1-15. Epub 2020 May 13.

Department of Psychology, The Chinese University of Hong Kong , Hong Kong.

Depression is a common and challenging comorbid condition in people with pathological dissociation. To our knowledge, this preliminary study is the first study that has looked at the clinical correlates of depression in a sample of people with pathological dissociation (N = 72). We found that severe depression is common in this sample and that depression is associated with dissociative symptoms, post-traumatic stress disorder (PTSD) symptoms, borderline personality disorder symptoms and clinical recovery; the level of depression is also associated with both childhood and adulthood betrayal trauma but not with childhood and adulthood trauma with less betrayal. Read More

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http://dx.doi.org/10.1080/15299732.2020.1760168DOI Listing

[Cannabis: Similarities and differences with tobacco].

Rev Mal Respir 2020 Jun 4;37(6):479-487. Epub 2020 May 4.

Service de toxicologie et pharmacocinétique, CHU de La-Milétrie, BP 577, 86021 Poitiers, France.

Nicotine is the specific psychoactive substance of tobacco while tetrahydrocannabinol (THC) is the specific component of cannabis. The inhalation technique of cannabis is different from that of tobacco smoking: the volume of puffs is larger, inhalation is deeper, and pulmonary retention time is longer. Cannabis addiction is difficult to evaluate, both products often being smoked concomitantly. Read More

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http://dx.doi.org/10.1016/j.rmr.2020.04.002DOI Listing

[Pilot Data from the Evaluation of an Integrative Body Psychotherapy Program for Patients with Psychogenic Non-Epileptic Seizures].

Psychother Psychosom Med Psychol 2020 Apr 30. Epub 2020 Apr 30.

Medizinische Klinik mit Schwerpunkt Psychosomatik, Charité Universitätsmedizin Berlin.

Psychogenic non-epileptic seizures (PNES) occur in the context of various diseases. Therefore, PNES patients represent a heterogeneous group with different causative disorders. The etiology is still poorly understood. Read More

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http://dx.doi.org/10.1055/a-1146-3208DOI Listing

Shame, dissociative seizures and their correlation among traumatised female Yazidi with experience of sexual violence.

Br J Psychiatry 2020 Mar;216(3):138-143

Researcher and Lecturer, Clinic for Psychiatry and Psychotherapy, Division of Psychosomatic Medicine and Psychotherapy, Universitaetskliniken des Saarlandes; and Head, Division of Psychosomatic Medicine and Psychotherapy, Universitaetskliniken des Saarlandes, Germany.

Background: Survivors of Islamic State of Iraq and Syria (ISIS) captivity are at high risk of developing mental disorders such as post-traumatic stress disorder (PTSD).

Aims: This study looks at the correlation between sexual abuse, shame, somatoform or bodily distress disorders, and dissociative seizures (psychogenic non-epileptic seizures).

Method: The psychological effects of traumatic events and dissociative seizure were assessed in Yazidi women who were held captive by ISIS in Northern Iraq between 2014 and 2018. Read More

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http://dx.doi.org/10.1192/bjp.2020.2DOI Listing
March 2020
7.991 Impact Factor

From brooding to detachment: Rumination longitudinally predicts an increase in depersonalization and derealisation.

Psychol Psychother 2020 Apr 25. Epub 2020 Apr 25.

Ben-Gurion University of the Negev, Be'er-Sheva, Israel.

Objectives: Depersonalization-derealization (DEP-DER) is a dissociative experience which is related to psychopathology and distress. Yet, the aetiological factors leading to DEP-DER are not sufficiently clear. In this study, we suggest rumination as one possible antecedent. Read More

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http://dx.doi.org/10.1111/papt.12279DOI Listing
April 2020
1.817 Impact Factor

Prevalence of Dissociative Convulsions in Patients with Dissociative Disorder in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.

JNMA J Nepal Med Assoc 2019 Sep-Oct;57(219):320-322

Department of Psychiatry, Narayani Hospital, Birgunj, Nepal.

Introduction: Dissociative disorder is one of the common psychiatric problems encountered very frequently in the hospital setting. The aim of the study is to find out the prevalence of dissociative convulsions type in patients suffering from dissociative disorder attending Psychiatry outpatient department of a tertiary care hospital.

Methods: The descriptive cross-sectional study was carried out in a tertiary care hospital from February 2019 to July 2019 after taking ethical approval (MEMG/IRC/210/GA). Read More

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Sensory Processing Difficulties in Functional Neurological Disorder: A Possible Predisposing Vulnerability?

Psychosomatics 2020 Jul - Aug;61(4):343-352. Epub 2020 Feb 22.

Functional Neurology Research Group, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Neuropsychiatry Unit, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address:

Background: Functional neurological disorder (FND) is a prevalent neuropsychiatric condition characterized by sensorimotor difficulties. Patients with FND at times report that sensory experiences trigger and/or exacerbate their symptoms. Sensory processing difficulties are also commonly reported in other psychiatric disorders frequently comorbid in FND, suggesting that contextualizing sensory profiles in FND within a biopsychosocial model may be clinically relevant. Read More

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http://dx.doi.org/10.1016/j.psym.2020.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329616PMC
February 2020

What urologists need to know about ketamine-induced uropathy: A systematic review.

Neurourol Urodyn 2020 04 25;39(4):1049-1062. Epub 2020 Mar 25.

Department of Urology, IRCCS INRCA, Ancona, Italy.

Aims: Ketamine is a general anesthetic. Dissociative effects and low cost led ketamine becoming an illegal recreational drug in young adults. Ketamine-induced uropathy (KIU) is one of the complications observed in abusers. Read More

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http://dx.doi.org/10.1002/nau.24341DOI Listing

Acute amnestic syndromes.

J Neurol Sci 2020 Jun 18;413:116781. Epub 2020 Mar 18.

Department of Cognitive Neurology, Neuropsychiatry and Neuropsychology, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina.

Acute amnestic syndromes are usually rare clinical events occurring in emergency situations. Etiological diagnosis can be challenging and underlying causes diverse. They can be transient and totally reversible, or accompanied by other neurological symptoms resulting in serious and irreversible brain damage. Read More

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http://dx.doi.org/10.1016/j.jns.2020.116781DOI Listing

The contributions of emotion regulation difficulties and dissociative symptoms to functional impairment among civilian inpatients with posttraumatic stress symptoms.

Psychol Trauma 2020 Mar 23. Epub 2020 Mar 23.

Department of Psychology, Neuroscience, and Behaviour, McMaster University.

Background: Functional impairment among individuals with posttraumatic stress disorder (PTSD) represents a significant factor in recovery. Critically, functional impairment appears to persist following remission of PTSD symptoms. To date, work investigating functional impairment among individuals with PTSD has focused on PTSD symptom clusters, excluding other relevant symptoms, including emotion regulation difficulties and dissociative symptoms. Read More

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http://dx.doi.org/10.1037/tra0000576DOI Listing

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.

Authors:
Paul M Thompson Neda Jahanshad Christopher R K Ching Lauren E Salminen Sophia I Thomopoulos Joanna Bright Bernhard T Baune Sara Bertolín Janita Bralten Willem B Bruin Robin Bülow Jian Chen Yann Chye Udo Dannlowski Carolien G F de Kovel Gary Donohoe Lisa T Eyler Stephen V Faraone Pauline Favre Courtney A Filippi Thomas Frodl Daniel Garijo Yolanda Gil Hans J Grabe Katrina L Grasby Tomas Hajek Laura K M Han Sean N Hatton Kevin Hilbert Tiffany C Ho Laurena Holleran Georg Homuth Norbert Hosten Josselin Houenou Iliyan Ivanov Tianye Jia Sinead Kelly Marieke Klein Jun Soo Kwon Max A Laansma Jeanne Leerssen Ulrike Lueken Abraham Nunes Joseph O' Neill Nils Opel Fabrizio Piras Federica Piras Merel C Postema Elena Pozzi Natalia Shatokhina Carles Soriano-Mas Gianfranco Spalletta Daqiang Sun Alexander Teumer Amanda K Tilot Leonardo Tozzi Celia van der Merwe Eus J W Van Someren Guido A van Wingen Henry Völzke Esther Walton Lei Wang Anderson M Winkler Katharina Wittfeld Margaret J Wright Je-Yeon Yun Guohao Zhang Yanli Zhang-James Bhim M Adhikari Ingrid Agartz Moji Aghajani André Aleman Robert R Althoff Andre Altmann Ole A Andreassen David A Baron Brenda L Bartnik-Olson Janna Marie Bas-Hoogendam Arielle R Baskin-Sommers Carrie E Bearden Laura A Berner Premika S W Boedhoe Rachel M Brouwer Jan K Buitelaar Karen Caeyenberghs Charlotte A M Cecil Ronald A Cohen James H Cole Patricia J Conrod Stephane A De Brito Sonja M C de Zwarte Emily L Dennis Sylvane Desrivieres Danai Dima Stefan Ehrlich Carrie Esopenko Graeme Fairchild Simon E Fisher Jean-Paul Fouche Clyde Francks Sophia Frangou Barbara Franke Hugh P Garavan David C Glahn Nynke A Groenewold Tiril P Gurholt Boris A Gutman Tim Hahn Ian H Harding Dennis Hernaus Derrek P Hibar Frank G Hillary Martine Hoogman Hilleke E Hulshoff Pol Maria Jalbrzikowski George A Karkashadze Eduard T Klapwijk Rebecca C Knickmeyer Peter Kochunov Inga K Koerte Xiang-Zhen Kong Sook-Lei Liew Alexander P Lin Mark W Logue Eileen Luders Fabio Macciardi Scott Mackey Andrew R Mayer Carrie R McDonald Agnes B McMahon Sarah E Medland Gemma Modinos Rajendra A Morey Sven C Mueller Pratik Mukherjee Leyla Namazova-Baranova Talia M Nir Alexander Olsen Peristera Paschou Daniel S Pine Fabrizio Pizzagalli Miguel E Rentería Jonathan D Rohrer Philipp G Sämann Lianne Schmaal Gunter Schumann Mark S Shiroishi Sanjay M Sisodiya Dirk J A Smit Ida E Sønderby Dan J Stein Jason L Stein Masoud Tahmasian David F Tate Jessica A Turner Odile A van den Heuvel Nic J A van der Wee Ysbrand D van der Werf Theo G M van Erp Neeltje E M van Haren Daan van Rooij Laura S van Velzen Ilya M Veer Dick J Veltman Julio E Villalon-Reina Henrik Walter Christopher D Whelan Elisabeth A Wilde Mojtaba Zarei Vladimir Zelman

Transl Psychiatry 2020 Mar 20;10(1):100. Epub 2020 Mar 20.

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i. Read More

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http://dx.doi.org/10.1038/s41398-020-0705-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083923PMC
March 2020
4.360 Impact Factor

Peri-ictal responsiveness to the social environment is greater in psychogenic nonepileptic than epileptic seizures.

Epilepsia 2020 Apr 10;61(4):758-765. Epub 2020 Mar 10.

Sheffield Teaching Hospitals National Health Service Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.

Objective: To look for evidence of peri-ictal social interaction in psychogenic nonepileptic seizures (PNES) and epileptic seizures exploring the notion of PNES as a form of nonverbal communication.

Methods: Video recordings of typical seizures experienced by patients with epilepsy and PNES were obtained in a naturalistic social setting (residential epilepsy monitoring unit). Video analysis by three nonexpert clinicians identified 18 predefined semiological and interactional features indicative of apparent impairment of consciousness or of peri-ictal responsiveness to the social environment with assessment of interrater reliability using Fleiss κ. Read More

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http://dx.doi.org/10.1111/epi.16471DOI Listing
April 2020
4.571 Impact Factor

Assessing Voice Hearing in Trauma Spectrum Disorders: A Comparison of Two Measures and a Review of the Literature.

Front Psychiatry 2019 24;10:1011. Epub 2020 Feb 24.

Department of Psychiatry, Harvard Medical School, Boston, MA, United States.

Voice hearing (VH) can occur in trauma spectrum disorders (TSD) such as posttraumatic stress disorder (PTSD) and dissociative disorders. However, previous estimates of VH among individuals with TSD vary widely. In this study, we sought to better characterize the rate and phenomenology of VH in a sample of 70 women with TSD related to childhood abuse who were receiving care in a specialized trauma program. Read More

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http://dx.doi.org/10.3389/fpsyt.2019.01011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050446PMC
February 2020

Dissociation between reduced diaphragm inspiratory motion and normal diaphragm thickening in acute chronic pulmonary obstructive disease exacerbation: a case report.

Medicine (Baltimore) 2020 Mar;99(10):e19390

Institut de Myologie, CHU Pitié Salpetrière, APHP, Paris, France.

Introduction: Patients with chronic pulmonary obstructive disease (COPD) are at risk of acute exacerbation. Diaphragm muscle is classically highly solicited in COPD exacerbation.

Patient Concerns: A COPD patient was admitted because of acute dyspnea with wheezing. Read More

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http://dx.doi.org/10.1097/MD.0000000000019390DOI Listing
March 2020
5.723 Impact Factor

Severity of panic disorder, adverse events in childhood, dissociation, self-stigma and comorbid personality disorders Part 1: Relationships between clinical, psychosocial and demographic factors in pharmacoresistant panic disorder patients.

Neuro Endocrinol Lett 2019 Dec;40(5):233-246

Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital, 77520 Olomouc, Czech Republic.

Objectives: Little is known about the relation between severity of panic disorder, adverse events in childhood, dissociation, self-stigma and comorbid personality disorders. The aim of this study is to look for the intercorrelations between these factors.

Method: The study explores the relation between clinical, demographic and social factors in panic disorder using cross sectional design. Read More

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December 2019

[Age identity disorders (infantilism/ puerilism) in the psychopathological space of endogenous diseases].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(1):7-19

Kazan State Medical Academy - Branch of 'Russian Medical Academy of Continuous Professional Education', Kazan, Russia.

Aim: A comparative psychopathological and psychometric analysis of age identity disorders (AID) - infantilism and puerilism - on the model of schizophrenia proceeding with hysterical symptoms.

Material And Methods: Results of the psychopathological study of 42 patients with schizophrenia and schizophrenia spectrum disorders (SSD), with well-marked signs of AID in the course of the disease (22 sub. - infantilism; 20 sub. Read More

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http://dx.doi.org/10.17116/jnevro20201200117DOI Listing

Sleep, trauma, fantasy and cognition in dissociative identity disorder, post-traumatic stress disorder and healthy controls: a replication and extension study.

Eur J Psychotraumatol 2020 13;11(1):1705599. Epub 2020 Jan 13.

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

: Two aetiology models for dissociative identity disorder (DID) have been proposed, namely a childhood Trauma Model and an iatrogenic or Fantasy model. A recent study indicated that sleep disturbances underlie dissociative symptomatology. : Our current study aims to test whether this finding can be replicated in an independent sample and to investigate if this finding still holds after correcting for childhood and adult traumatization. Read More

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http://dx.doi.org/10.1080/20008198.2019.1705599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006753PMC
January 2020

Describing the indescribable: A qualitative study of dissociative experiences in psychosis.

PLoS One 2020 19;15(2):e0229091. Epub 2020 Feb 19.

Department of Experimental Psychology, Oxford Centre for Anxiety Disorders and Trauma, University of Oxford, Oxford, United Kingdom.

Background: Despite its long history, dissociation remains under-recognised clinically, partly due to difficulties identifying dissociative symptoms. Qualitative research may support its recognition by providing a lived experience perspective. In non-affective psychosis, identification of dissociation may be particularly important given that such experiences have been implicated its development and maintenance. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229091PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029850PMC

The Association between General and Pathological Dissociation and Disaster-Related Psychopathology in Directly Exposed Survivors.

Psychiatry 2020 Feb 18:1-14. Epub 2020 Feb 18.

: Dissociation and trauma have a well-documented relationship, and dissociation is assumed to result from trauma exposure. If trauma generates dissociative psychopathology, it should be observed after exposure to disaster and be associated with disaster-related psychopathology. Few studies have focused specifically on dissociation as an outcome of disaster trauma. Read More

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http://dx.doi.org/10.1080/00332747.2020.1716440DOI Listing
February 2020

Psychological Interventions for Dissociative disorders.

Indian J Psychiatry 2020 Jan 17;62(Suppl 2):S280-S289. Epub 2020 Jan 17.

Department of Psychiatry , MGM New Bombay Hospital, Vashi, Navi Mumbai, Maharashtra, India.

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http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_777_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001344PMC
January 2020

Stress- and trauma-related blockade of episodic-autobiographical memory processing.

Neuropsychologia 2020 03 29;139:107364. Epub 2020 Jan 29.

University of Bielefeld, Germany. Electronic address:

Memory disorders without a direct neural substrate still belong to the riddles in neuroscience. Although they were for a while dissociated from research and clinical arenas, risking becoming forgotten diseases, they sparked novel interests, paralleling the refinements in functional neuroimaging and neuropsychology. Although Endel Tulving has not fully embarked himself on exploring this field, he had published at least one article on functional amnesia (Schacter et al. Read More

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http://dx.doi.org/10.1016/j.neuropsychologia.2020.107364DOI Listing

Spontaneous Resolution of Dorsal Midbrain Syndrome Caused by a Pineal Cyst.

World Neurosurg 2020 Apr 27;136:289-292. Epub 2020 Jan 27.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Centre, Toronto, Ontario, Canada. Electronic address:

Background: Pineal lesions are common causes of dorsal midbrain syndrome and typically require surgical intervention in symptomatic patients. We describe a unique case of spontaneous resolution of dorsal midbrain syndrome resulting from a pineal gland cyst.

Case Description: A 23-year-old woman developed a supranuclear upgaze palsy, convergence-retraction nystagmus, and light-near dissociation from a pineal gland cyst (1. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.01.144DOI Listing

Sublingual Ketamine: An Option for Increasing Accessibility of Ketamine Treatments for Depression?

J Clin Psychiatry 2020 Jan 28;81(1). Epub 2020 Jan 28.

Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.4088/JCP.19lr13146DOI Listing
January 2020

Terminology for psychogenic nonepileptic seizures: Making the case for "functional seizures".

Epilepsy Behav 2020 Mar 24;104(Pt A):106895. Epub 2020 Jan 24.

Section of Cognitive Neuropsychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Electronic address:

Purpose: The purpose of the study was to review the literature on the terminologies for psychogenic nonepileptic seizures (PNES) and make a proposal on the terminology of this condition. This proposal reflects the authors' own opinions.

Methods: We systematically searched MEDLINE (accessed from PubMed) and EMBASE from inception to October 10, 2019 for articles written in English with a main focus on PNES (with or without discussion of other functional neurological disorders) and which either proposed or discussed the accuracy or appropriateness of PNES terminologies. Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.106895DOI Listing