7,144 results match your criteria Disseminate and Recurrent Infundibular Folliculitis


Women's Health Curricula in Internal Medicine Residency Programs: A Scoping Review.

J Womens Health (Larchmt) 2019 Feb 22. Epub 2019 Feb 22.

1 Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: Despite national efforts to expand women's health education, internal medicine (IM) residents remain unprepared to provide comprehensive care to women. The objectives of this scoping review are to provide an overview of published women's health curricula in IM residency programs and to identify potential areas for improvement.

Methods: Studies were identified using PubMed, Embase, Cochrane Library, Scopus, Education Resources Information Center (ERIC), Web of Science, and MedEdPORTAL. Read More

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http://dx.doi.org/10.1089/jwh.2018.7317DOI Listing
February 2019

Evaluating a childhood obesity program with the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework.

Prev Med Rep 2019 Mar 24;13:321-326. Epub 2019 Jan 24.

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.

Primary care providers can use behavioral lifestyle interventions to effectively treat children with overweight and obesity, but implementing these interventions is challenging. Most childhood obesity intervention evaluation studies focus on effectiveness. Few studies describe implementation. Read More

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http://dx.doi.org/10.1016/j.pmedr.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369326PMC

Global Epidemiology of Bat Coronaviruses.

Viruses 2019 Feb 20;11(2). Epub 2019 Feb 20.

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.

Bats are a unique group of mammals of the order . They are highly diversified and are the group of mammals with the second largest number of species. Such highly diversified cell types and receptors facilitate them to be potential hosts of a large variety of viruses. Read More

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http://dx.doi.org/10.3390/v11020174DOI Listing
February 2019

Evidence for a de novo, dominant germ-line mutation causative of osteogenesis imperfecta in two Red Angus calves.

Mamm Genome 2019 Feb 20. Epub 2019 Feb 20.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68583-0905, USA.

A genetic disorder, osteogenesis imperfecta (OI) is broadly characterized by connective tissue abnormalities and bone fragility most commonly attributed to alterations in Type I collagen. Two Red Angus calves by the same sire presented with severe bone and dental fragility, blue sclera, and evidence of in utero fractures consistent with OI congenita. Comparative analyses with human cases suggested the OI in these calves most closely resembled that classified as OI Type II. Read More

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http://dx.doi.org/10.1007/s00335-019-09794-4DOI Listing
February 2019

Knowledge, Attitude, and Practice of Mothers towards Infant Oral Healthcare.

Int J Clin Pediatr Dent 2018 Sep-Oct;11(5):435-439. Epub 2018 Oct 1.

Senior Lecturer, Department of Pedodontics and Preventive Dentistry, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Odisha, India.

Background: Among all the oral diseases, dental caries is the most common chronic disease affecting the children. Early childhood caries is one of the most severe forms of dental caries affecting the children less than 3 years. Though dental caries is preventable, not much importance has been given to the preventive aspect of dental caries. Read More

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http://dx.doi.org/10.5005/jp-journals-10005-1553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379533PMC
October 2018

The Antibiotic Neomycin Enhances Coxsackievirus Plaque Formation.

mSphere 2019 Feb 20;4(1). Epub 2019 Feb 20.

Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

Coxsackievirus typically infects humans via the gastrointestinal tract, which has a large number of microorganisms collectively referred to as the microbiota. To study how the intestinal microbiota influences enteric virus infection, several groups have used an antibiotic regimen in mice to deplete bacteria. These studies have shown that bacteria promote infection with several enteric viruses. Read More

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http://dx.doi.org/10.1128/mSphere.00632-18DOI Listing
February 2019

Outcomes of a Gratitude Practice in an Online Community of Caring.

J Altern Complement Med 2019 Feb 20. Epub 2019 Feb 20.

1 Earl E. Bakken Center for Spirituality & Healing, The University of Minnesota, Minneapolis, MN.

Objectives: CaringBridge (CB) is a web-based social network where people share information, enlist support, and access resources following a difficult diagnosis; it can also be used to disseminate supportive self-care tools, such as a gratitude practice, for its users. Gratitude practices are shown to reduce stress and fear, improve sleep, and increase positive emotions and overall well-being. The purpose of this article was to report the findings of a brief gratitude intervention delivered to CB users. Read More

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http://dx.doi.org/10.1089/acm.2018.0460DOI Listing
February 2019

Cochrane Eyes and Vision: a perspective introducing Cochrane Corner in Eye.

Eye (Lond) 2019 Feb 19. Epub 2019 Feb 19.

Moorfields Eye Hospital NHS Foundation Trust, City Road, London, EC1V 2PD, UK.

In 1972, Archie Cochrane wrote "It is surely a great criticism of our profession that we have not organised a critical summary, by specialty or subspecialty, adapted periodically, of all relevant randomised controlled trials". The Cochrane Collaboration arose in response to Archie Cochrane's challenge. Cochrane Eyes and Vision aims to prepare and promote access to systematic reviews of interventions for preventing or treating eye conditions and/or visual impairment, and helping people adjust to visual impairment or blindness. Read More

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http://www.nature.com/articles/s41433-019-0357-7
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http://dx.doi.org/10.1038/s41433-019-0357-7DOI Listing
February 2019
1 Read

Frailty in patients undergoing transcatheter aortic valve implantation: a protocol for a systematic review.

BMJ Open 2019 Feb 19;9(2):e024163. Epub 2019 Feb 19.

Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.

Introduction: Aortic stenosis is a significant cause of morbidity and mortality in older patients. The advent of transcatheter aortic valve implantation (TAVI) offers an alternative to surgical aortic valve replacement for patients with severe symptomatic aortic stenosis who are at high or intermediate risk of adverse events. Existing evidence highlights the importance of frailty as a predictor of poor outcomes post-TAVI. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024163DOI Listing
February 2019

Evaluating the impact of a community-based social prescribing intervention on people with type 2 diabetes in North East England: mixed-methods study protocol.

BMJ Open 2019 Jan 15;9(1):e026826. Epub 2019 Jan 15.

Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.

Introduction: Social prescribing enables healthcare professionals to use voluntary and community sector resources to improve support for people with long-term conditions. It is widely promoted in the UK as a way to address complex health, psychological and social issues presented in primary care, yet there is insufficient evidence of effectiveness or value for money. This study aims to evaluate the impact and costs of a link-worker social prescribing intervention on the health and healthcare use of adults aged 40-74 with type 2 diabetes, living in a multi-ethnic area of high socioeconomic deprivation. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340458PMC
January 2019

Children with Hemiparesis Arm and Movement Project (CHAMP): protocol for a multisite comparative efficacy trial of paediatric constraint-induced movement therapy (CIMT) testing effects of dosage and type of constraint for children with hemiparetic cerebral palsy.

BMJ Open 2019 Jan 15;9(1):e023285. Epub 2019 Jan 15.

University of Virginia, Charlottesville, Virginia, USA.

Introduction: The Children with Hemiparesis Arm and Movement Project (CHAMP) addresses two pressing issues concerning paediatric constraint-induced movement therapy (CIMT): effects of two dosages and two types of constraint on functional outcomes. Systematic reviews conclude that CIMT is one of the most efficacious treatments, but wide variations in treatment protocols, outcome measures and patient characteristics have prevented conclusions about potential effects of dosage levels and constraint methods.

Methods And Analysis: CHAMP is a multisite comparative efficacy randomised controlled trial of 135 children (2-8 years) with hemiparetic cerebral palsy. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340418PMC
January 2019

Effects of Tillage Practices on Dissemination and Spatial Patterns of Heterodera glycines and Soybean Yield.

Plant Dis 2007 Aug;91(8):973-978

Department of Plant Pathology, Iowa State University, Ames 50011-1020.

Two field experiments were conducted in central Iowa to assess the effects of tillage on Heterodera glycines dissemination and reproduction and soybean (Glycine max) yield. Plots in both experiments were artificially infested with equivalent numbers of H. glycines cysts. Read More

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http://dx.doi.org/10.1094/PDIS-91-8-0973DOI Listing

Health Information Engagement Factors in Malaysia: A Content Analysis of Facebook Use by the Ministry of Health in 2016 and 2017.

Int J Environ Res Public Health 2019 Feb 18;16(4). Epub 2019 Feb 18.

Director General's Office, Ministry of Health, Putrajaya 62590, Malaysia.

Health organizations have widely adopted social media for health promotion, public health communication conveyance, and organizational promotion activities. However, little published data exists on the factors that facilitate health information diffusion in South East Asia, especially Malaysia compared with Western countries. This study aimed to investigate factors associated with good engagement rates among internet users on the Facebook (FB) page of Ministry of Health Malaysia. Read More

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http://dx.doi.org/10.3390/ijerph16040591DOI Listing
February 2019

Role of persistent cascades in diffusion.

Phys Rev E 2019 Jan;99(1-1):012323

The Charles Stark Draper Laboratory, Cambridge, Massachusetts 02139, USA.

We define a structural property of real-world large-scale communication networks consisting of the recurring patterns of communication among individuals, which we term persistent cascades. Using methods of inexact tree matching and agglomerative clustering, we group these patterns into classes which we claim represent some underlying way in which individuals tend to disseminate information. We extend methods from epidemic modeling to offer a way to analytically model this recurring structure in a random network, and comparing to the data, we find that the real cascading structure is significantly larger and more recurrent than the random model. Read More

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http://dx.doi.org/10.1103/PhysRevE.99.012323DOI Listing
January 2019

everyBody-Tailored online health promotion and eating disorder prevention for women: Study protocol of a dissemination trial.

Internet Interv 2019 Apr 26;16:20-25. Epub 2018 Feb 26.

Technische Universität Dresden, Institut für Klinische Psychologie & Psychotherapie, Chemnitzer Str. 46, 01187 Dresden, Germany.

Background: Although there is extensive evidence for the efficacy of online eating disorder (ED) prevention programs in clinical trials, these programs have rarely been adopted beyond the trial phase and offered to a wider audience. As risk factors for eating disorders are partly associated with overweight and overweight in turn is correlated to disordered eating, this study will offer a combined eating disorder prevention program which also promotes a balanced lifestyle to normal weight and overweight individuals alike. The efficacy of the program has been proven in previous trials. Read More

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http://dx.doi.org/10.1016/j.invent.2018.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364518PMC

Facilitators and barriers to enrolling in falls prevention programming among community dwelling older adults.

Arch Gerontol Geriatr 2019 Jan 28;82:106-113. Epub 2019 Jan 28.

Simmons College, Physical Therapy Department, 300 The Fenway, Boston, MA, 02115, United States. Electronic address:

The purpose of this cross-sectional survey study was to identify factors that increase the likelihood of enrolling in falls prevention programming among community dwelling older adults. A convenience sample of 369 participants completed a written, selfadministered questionnaire on history and beliefs related to falls, and facilitators and barriers associated with enrollment. History of falling, fear of falling, self-efficacy, and recognition of program benefits were all associated with a greatly likelihood to enroll in falls prevention programming. Read More

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http://dx.doi.org/10.1016/j.archger.2019.01.006DOI Listing
January 2019
1 Read

Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder.

Eur Psychiatry 2019 Feb 11;58:19-26. Epub 2019 Feb 11.

Rita Levi Montalcini Department of Neuroscience, University of Turin, Italy and San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.

Background: The duration of untreated illness (DUI) is a potentially modifiable parameter associated with worst prognosis in several psychiatric disorders, but poorly investigated in Obsessive-Compulsive Disorder (OCD). Our aims were to estimate the mean DUI in a large sample of individuals with OCD and its impact on response to the first ever adequate SRI treatment.

Methods: We retrospectively examined records of 251 patients with OCD (SCID-I, DSM-IV) who referred to our Department and were prospectively and naturalistically treated according to International Guidelines. Read More

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http://dx.doi.org/10.1016/j.eurpsy.2019.01.017DOI Listing
February 2019
1 Read

Patient stakeholder engagement in research: A narrative review to describe foundational principles and best practice activities.

Health Expect 2019 Feb 13. Epub 2019 Feb 13.

Division of Hospital Medicine, University of California San Francisco, San Francisco, California.

Background: Health research is evolving to include patient stakeholders (patients, families and caregivers) as active members of research teams. Frameworks describing the conceptual foundations underlying this engagement and strategies detailing best practice activities to facilitate engagement have been published to guide these efforts.

Objective: The aims of this narrative review are to identify, quantify and summarize (a) the conceptual foundational principles of patient stakeholder engagement in research and (b) best practice activities to support these efforts. Read More

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http://dx.doi.org/10.1111/hex.12873DOI Listing
February 2019
3.410 Impact Factor

Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration.

Front Immunol 2019 29;10:80. Epub 2019 Jan 29.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.

Innate immune activation and chronic neuroinflammation are characteristic features of many neurodegenerative diseases including Parkinson's disease (PD) and may contribute to the pathophysiology of the disease. The discovery of misfolded alpha-synuclein (αSYN) protein aggregates, which amplify in a "prion-like" fashion, has led us to consider that pathogenic αSYN might be hijacking the activation and mobilization mechanism of the peripheral immune system to reach and disseminate within the CNS. Furthermore, our lab and other groups have recently shown that αSYN can adopt distinct fibril conformations or "strains" with varying levels of pathogenic impact. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361759PMC
January 2019
1 Read

Persistence and Diffusion of C-Positive CC130 MRSA Isolates in Dairy Farms in Meurthe-et-Moselle County (France).

Front Microbiol 2019 30;10:47. Epub 2019 Jan 30.

Pathogénie des Infections à Staphylocoque, Centre International de Recherche en Infectiologie, Lyon, France.

Methicillin resistance in (MRSA) is classically conferred by the acquisition of the A gene encoding an additional penicillin binding protein with low affinity for beta-lactams. A A variant, named C, was described in 2011. MRSA isolates harboring C of both animal and human origin have since been collected in different European countries. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2019.00047
Publisher Site
http://dx.doi.org/10.3389/fmicb.2019.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363682PMC
January 2019
3 Reads

Head Injury in Soccer: From Science to the Field; summary of the head injury summit held in April 2017 in New York City, New York.

Br J Sports Med 2019 Feb 13. Epub 2019 Feb 13.

Duke Sport Sciences Institute, Duke University Health System, Durham, North Carolina, USA.

There has been an increased focus and awareness of head injury and sport-related concussion (SRC) across all sports from the medical and scientific communities, sports organisations, legislators, the media and the general population. Soccer, in particular, has been a focus of attention due to the popularity of the game, the frequency of SRC and the hypothesised effects of repetitive heading of the ball. Major League Soccer, US Soccer and the National Women's Soccer League jointly hosted a conference entitled, 'Head Injury in Soccer: From Science to the Field', on 21-22 April 2017 in New York City, New York. Read More

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http://dx.doi.org/10.1136/bjsports-2018-100232DOI Listing
February 2019
1 Read

Implementing Shared, Standardized Imaging Protocols to Improve Cross-Enterprise Workflow and Quality.

J Digit Imaging 2019 Feb 12. Epub 2019 Feb 12.

Department of Radiology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX, USA.

Value-based imaging requires appropriate utilization and the delivery of consistently high-quality imaging at an acceptable cost. Challenges include developing standardized imaging protocols, ensuring consistent application by technologists, and monitoring quality. These challenges increase as enterprises grow in geographical extent and complexity through mergers or partnerships. Read More

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http://dx.doi.org/10.1007/s10278-019-00185-4DOI Listing
February 2019

Cdk8 and Ssn801 Regulate Oxidative Stress Resistance and Virulence in Cryptococcus neoformans.

MBio 2019 Feb 12;10(1). Epub 2019 Feb 12.

Department of Molecular Microbiology, Washington University School of Medicine, Washington University, St. Louis, Missouri, USA

kills 200,000 people worldwide each year. After inhalation, this environmental yeast proliferates either extracellularly or within host macrophages. Under conditions of immunocompromise, cryptococci disseminate from the lungs to the brain, causing a deadly meningoencephalitis that is difficult and expensive to treat. Read More

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http://dx.doi.org/10.1128/mBio.02818-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372802PMC
February 2019

Using social media to disseminate education about Alzheimer's prevention & treatment: a pilot study on Alzheimer's universe (www.AlzU.org).

J Commun Healthc 2018 5;11(2):106-113. Epub 2018 May 5.

Department of Neurology, Weill Cornell Medicine, New York, NY, USA.

Background: The use of social media may be a valuable tool for dissemination of patient education interventions. However, in Alzheimer's disease (AD), little data exists about the effectiveness, associated cost, or conditions for utilization.

Methods: Alzheimer's Universe (www. Read More

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http://dx.doi.org/10.1080/17538068.2018.1467068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364853PMC
May 2018
1 Read

Development of a targeted educational intervention to increase pre-exposure prophylaxis uptake among cisgender men and transgender individuals who have sex with men and use methamphetamine in Seattle (WA, USA).

Sex Health 2019 Feb 11. Epub 2019 Feb 11.

Cisgender men and transgender individuals who have sex with men (MSM/TG) and use methamphetamine are at elevated risk for HIV and have had limited pre-exposure prophylaxis (PrEP) uptake. The aim of this study was to quantify the knowledge and use of PrEP, identify barriers to PrEP use, and develop a targeted educational campaign to promote PrEP among MSM/TG who use methamphetamine. We conducted three consultations with peer educators of Project Needle and Sex Education Outreach Network (NEON) to develop and disseminate educational materials. Read More

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http://dx.doi.org/10.1071/SH18060DOI Listing
February 2019

Escherichia coli on the internet: The power of YouTube to educate and influence consumer behavior regarding pathogenic bacteria.

Infect Dis Health 2019 Feb 6. Epub 2019 Feb 6.

William Paterson University, Department of Public Health, 366 University Hall, Wayne, NJ, 07470, USA.

Background: Proper education about food safety and hand hygiene helps to reduce the risk of exposure to Escherichia coli associated disease. The purpose of this study was to describe the 100 most widely viewed YouTube videos on the subject of E. coli to determine what consumers are viewing related to the hazards of, and reducing risk of exposure to, bacteria such as E. Read More

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http://dx.doi.org/10.1016/j.idh.2019.01.001DOI Listing
February 2019
2 Reads

Evidence review conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery: focus on anesthesiology for gynecologic surgery.

Reg Anesth Pain Med 2019 Feb 7. Epub 2019 Feb 7.

Anesthesiology, Hospital for Special Surgery, New York City, New York, USA.

Enhanced recovery after surgery (ERAS) protocols for gynecologic (GYN) surgery are increasingly being reported and may be associated with superior outcomes, reduced length of hospital stay, and cost savings. The Agency for Healthcare Research and Quality, in partnership with the American College of Surgeons and the Johns Hopkins Medicine Armstrong Institute for Patient Safety and Quality, has developed the Safety Program for Improving Surgical Care and Recovery, which is a nationwide initiative to disseminate best practices in perioperative care to more than 750 hospitals across five major surgical service lines in a 5-year period. The program is designed to identify evidence-based process measures shown to prevent healthcare-associated conditions and hasten recovery after surgery, integrate those into a comprehensive service line-based pathway, and assist hospitals in program implementation. Read More

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http://dx.doi.org/10.1136/rapm-2018-100071DOI Listing
February 2019
1 Read

[Analysis of over-the-counter medicines’ information and strategies oriented to the community for improving its access and quality.]

Rev Fac Cien Med Univ Nac Cordoba 2018 12 5;75(4):248-254. Epub 2018 Dec 5.

Departamento de Farmacología Facultad de Ciencias Químicas Universidad Nacional de Córdoba Haya de la Torre y Medina Allende s/n Ciudad Universitaria (5000) Córdoba..

Introduction: The Disposición ANMAT 753/2012 states definitions and guidelines about the information that inserts and labels must include in nonprescription drugs (also known as over-the-counter or OTC drugs).

Aim: Aims: to analyze the adequacy to the norm in a sample of OTC drugs; promote and disseminate strategic viable actions for being developed by pharmacists to improve the patient’s information. formulated. Read More

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http://dx.doi.org/10.31053/1853.0605.v75.n4.21599DOI Listing
December 2018

Cross-sectional Evaluation of Home Enteral Nutrition Practice in the United States in the Context of the New Enteral Connectors.

JPEN J Parenter Enteral Nutr 2019 Feb 7. Epub 2019 Feb 7.

Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA.

Purpose: The increased prevalence of home enteral nutrition (HEN), reemergence of blenderized tube feeding (BTF), and conversion of enteral connectors to the ISO 80369-3 standard are creating a significant need to better understand the practices of the HEN population. A cross-sectional survey of current HEN consumers was conducted to evaluate the demographics of HEN consumers, including formulas and feeding tubes being used.

Methods: In order to disseminate the survey to a wide range of HEN consumers, we partnered with private infusion companies (Coram and Pediatric Home Services) along with the Oley and Tube Feeding Awareness Foundations. Read More

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http://dx.doi.org/10.1002/jpen.1510DOI Listing
February 2019

Nutritional and Health Benefits of Jackfruit ( Lam.): A Review.

Int J Food Sci 2019 6;2019:4327183. Epub 2019 Jan 6.

Department of Food Science and Technology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

Lam., which is commonly known as jackfruit is a tropical climacteric fruit, belonging to Moraceae family, is native to Western Ghats of India and common in Asia, Africa, and some regions in South America. It is known to be the largest edible fruit in the world. Read More

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http://dx.doi.org/10.1155/2019/4327183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339770PMC
January 2019

Walk This Way: Our Perspective on Challenges and Opportunities for Extension Statewide Walking Promotion Programs.

J Nutr Educ Behav 2019 Feb 2. Epub 2019 Feb 2.

Department of Health Promotion, College of Public Health, University of Nebraska Medical Center, Omaha, NE.

Evidence-based walking programs exist and some have been tailored specifically for the national Cooperative Extension System; however, program outcomes and translational challenges and successes are underreported. This has presented a challenge to scaling the best-fit intervention for walking promotion within this national system. Here, we describe existing open-access walking programs as well as implications for improving the fit and sustainability of this intervention type within the system. Read More

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http://dx.doi.org/10.1016/j.jneb.2018.12.010DOI Listing
February 2019

The Diagnostic Challenge of an Infrequent Spectrum of Infection.

Case Rep Radiol 2019 2;2019:5970648. Epub 2019 Jan 2.

MD, Radiologist, Department of Radiology of the Medical School of the University of São Paulo, São Paulo, SP, Brazil.

Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Read More

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http://dx.doi.org/10.1155/2019/5970648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334315PMC
January 2019

Does lack of deeper understanding of shared decision making explains the suboptimal performance on crucial parts of it? An example from breast cancer care.

Eur J Oncol Nurs 2019 Feb 15;38:92-97. Epub 2018 Dec 15.

School CAPHRI, Care and Public Health Research Institute, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, the Netherlands; Department of Family Medicine, Maastricht University, Debeyeplein 1, 6229 ER, Maastricht, the Netherlands. Electronic address:

Purpose: Although most of the clinicians in breast cancer care seem to approve of shared decision making (SDM), actual implementation is limited. The aim of this study was to explore the experiences, issues and concerns of early-adopter professionals with regards to shared decision making.

Methods: This qualitative descriptive study was part of a pilot study aimed at implementing SDM in breast cancer teams. Read More

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http://dx.doi.org/10.1016/j.ejon.2018.12.004DOI Listing
February 2019

Mycoplasma bovis delay in apoptosis of macrophages is accompanied by increased expression of anti-apoptotic genes, reduced cytochrome C translocation and inhibition of DNA fragmentation.

Vet Immunol Immunopathol 2019 Feb 18;208:16-24. Epub 2018 Dec 18.

Vaccine and Infectious Disease Organization, International Vaccine Centre, University of Saskatchewan, 120 Veterinary Rd., Saskatoon, SK, S7N 5E3, Canada; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive. Saskatoon, SK, S7N 5B4, Canada. Electronic address:

Bacterial pathogens have evolved to manipulate host cell death and survival pathways for their intracellular persistence. Understanding the ability of a bacterium to induce or inhibit cell death is essential for elucidating the disease pathogenesis and suggesting potential therapeutic options to manage the infection. In recent years, apoptosis inhibition by different bacteria has been suggested as a mechanism of survival by allowing the pathogen to replicate and disseminate in the host. Read More

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http://dx.doi.org/10.1016/j.vetimm.2018.12.004DOI Listing
February 2019
1 Read

Patient recommendations for PrEP information dissemination at family planning clinics in Atlanta, Georgia.

Contraception 2019 Jan 31. Epub 2019 Jan 31.

Department of Medicine, Emory University School of Medicine.

Objective: Family planning (FP) clinics are an ideal setting to disseminate information about pre-exposure prophylaxis (PrEP), but little is known about women's preferences for learning about PrEP in this setting.

Study Design: We surveyed 500 women seeking care at 4 FP clinics in Atlanta. Before their provider visit, participants completed an HIV-risk screener. Read More

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http://dx.doi.org/10.1016/j.contraception.2018.12.008DOI Listing
January 2019
1 Read

Metastatic breast cancer incidence, site and survival in Australia, 2001-2016: a population-based health record linkage study protocol.

BMJ Open 2019 Feb 1;9(2):e026414. Epub 2019 Feb 1.

Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales, Australia.

Introduction: Advances in systemic therapy for early and metastatic breast cancer (BC) over the last two decades have improved patients' survival, but their impact on metastatic disease outcomes at a population level is not well described. The aim of this study is to investigate changes in the incidence, site and survival of metastatic disease for women with a first diagnosis of BC in 2001-2002 vs 2006-2007.

Methods And Analysis: Population-based retrospective cohort study of women with first primary invasive BC registered in the New South Wales (NSW) Cancer Registry in 2001-2002 and 2006-2007. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02641
Publisher Site
http://dx.doi.org/10.1136/bmjopen-2018-026414DOI Listing
February 2019
5 Reads

Problem in the profession: How and why writing skills in nursing must be improved.

J Prof Nurs 2019 Jan - Feb;35(1):57-64. Epub 2018 May 19.

The Catholic University of America, School of Nursing, 201 Gowan Hall, Michigan Avenue, NE Washington, DC 20064, United States.; The Catholic University of America, 219 Mullen Library, Michigan Avenue, NE Washington, DC 20064, United States.. Electronic address:

As a profession, nursing is obligated to disseminate knowledge by publishing research in the professional literature. Beyond producing scholarly work for publication, nurses need writing skills to complete doctoral dissertations and scholarly projects, and to succeed in obtaining funds for new nurse-directed business ventures. Ultimately, good writing skills are essential for the future of the nursing profession. Read More

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http://dx.doi.org/10.1016/j.profnurs.2018.05.005DOI Listing

Comparison of rapid vs in-depth qualitative analytic methods from a process evaluation of academic detailing in the Veterans Health Administration.

Implement Sci 2019 Feb 1;14(1):11. Epub 2019 Feb 1.

Center for Innovation to Implementation (Ci2i), VA Palo Alto Health Care System, Stanford University, 795 Willow Rd, Menlo Park, CA, 94025, USA.

Background: It is challenging to conduct and quickly disseminate findings from in-depth qualitative analyses, which can impede timely implementation of interventions because of its time-consuming methods. To better understand tradeoffs between the need for actionable results and scientific rigor, we present our method for conducting a framework-guided rapid analysis (RA) and a comparison of these findings to an in-depth analysis of interview transcripts.

Methods: Set within the context of an evaluation of a successful academic detailing (AD) program for opioid prescribing in the Veterans Health Administration, we developed interview guides informed by the Consolidated Framework for Implementation Research (CFIR) and interviewed 10 academic detailers (clinical pharmacists) and 20 primary care providers to elicit detail about successful features of the program. Read More

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http://dx.doi.org/10.1186/s13012-019-0853-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359833PMC
February 2019

Testing MD-Link, a Low-Cost Mobile Electrocardiography Monitoring Device, in Patients With Irregular Heartbeat: Protocol for a Cross-Sectional Study.

JMIR Res Protoc 2019 Jan 31;8(1):e2. Epub 2019 Jan 31.

Institute of Population, Health and Development, Hanoi, Viet Nam.

Background: Having mobile devices that provide patients with the ability to record and monitor the electrical activity of their heart enhances patient self-care and the early detection of irregular heartbeat (cardiac arrhythmia), yet few such devices exist in Vietnam. Challenges exist for introducing mobile electrocardiography (ECG) monitoring devices in Vietnam, including patient accessibility and affordability. A low-cost mobile ECG monitoring device designed and developed in Vietnam, which allows patients to easily measure their heart's electrical activity and navigate recordings, may be a solution. Read More

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http://dx.doi.org/10.2196/resprot.8762DOI Listing
January 2019

Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE) guidelines: a development protocol.

Int Endod J 2019 Jan 31. Epub 2019 Jan 31.

School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.

Randomized clinical trials are acknowledged as the most appropriate methodology for demonstrating the efficacy or effectiveness of one intervention as opposed to another and thus play a major role in clinical decision making. However, it is recognized that despite the existence of various guidelines, for example, the Consolidated Standards for Reporting Trials (CONSORT) statement, the quality of manuscripts describing randomised trials is often suboptimal. The current project aims to develop and disseminate new guidelines, Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE), to improve the planning and reporting quality of randomized trials in the field of Endodontics. Read More

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http://dx.doi.org/10.1111/iej.13087DOI Listing
January 2019

Borrelia burgdorferi infection in biglycan knock-out mice.

J Infect Dis 2019 Jan 29. Epub 2019 Jan 29.

Institute of Biomedicine, University of Turku, Turku, Finland.

Background: Borrelia burgdorferi sensu lato spirochetes (Borrelia) causing Lyme borreliosis are able to disseminate from the initial entry site to distant organs in the host. Outer surface adhesins are crucial in the bacterial dissemination and adhesion to various tissues. Two well-characterized Borrelia adhesins, Decorin binding proteins A and B, have been shown to bind to two host receptors, decorin and biglycan. Read More

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http://dx.doi.org/10.1093/infdis/jiz050DOI Listing
January 2019
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Talking across generations: Family communication about BRCA1 and BRCA2 genetic cancer risk.

J Genet Couns 2019 Jan 29. Epub 2019 Jan 29.

Behavioral Sciences Unit Proudly Supported by the Kids with Cancer Foundation, Kids Cancer Centre, Sydney Children's Hospital, Randwick, Australia.

While family communication about a BRCA1 or BRCA2 (BRCA1/2) pathogenic variant can be a catalyst for the uptake of risk-reducing measures in young adults, disseminating information within families and across generations is complex. This study aimed to explore how young adults and their families communicate about a BRCA1/2 pathogenic variant, from a family systems perspective. In-depth family interviews and questionnaires (N = 67 individuals; 21 families) were completed at four metropolitan and regional genetic clinics in Australia. Read More

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http://dx.doi.org/10.1002/jgc4.1055DOI Listing
January 2019
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The Role of Mucosal Immunity in Pertussis.

Front Immunol 2018 14;9:3068. Epub 2019 Jan 14.

Center of Infection and Immunity of Lille, Institut Pasteur de Lille, Lille, France.

Pertussis or whooping cough, mainly caused by , is a severe respiratory disease that can affect all age groups but is most severe and can be life-threatening in young children. Vaccines against this disease are widely available since the 1950s. Despite high global vaccination coverage, the disease is not under control in any country, and its incidence is even increasing in several parts of the world. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.03068
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http://dx.doi.org/10.3389/fimmu.2018.03068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339907PMC
January 2019
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A review of innate and adaptive immunity to coccidioidomycosis.

Med Mycol 2019 Feb;57(Supplement_1):S85-S92

Infectious Diseases Section, VA Healthcare San Diego, California, USA.

Coccidioidomycosis is a human fungal disease cause by inhalation of aerosol spores produced by Coccidioides posadasii or Coccidioides immitis. This disease is a common cause of community-acquired pneumonia in the endemic areas of the Southwestern United States. It also can present as a life-threatening disease as the fungal cells disseminate to skin, bone, and central nervous system. Read More

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http://dx.doi.org/10.1093/mmy/myy146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347076PMC
February 2019
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A Positive Deviance Approach to Improve Familial Authorization for Organ Donation.

Clin Transplant 2019 Jan 28:e13488. Epub 2019 Jan 28.

Department of Communication, University at Buffalo - State University of New York.

The current study evaluates the Positive Deviance Donation Collaborative, a communication training program designed to identify and disseminate behaviors of requesters with above-average rates of familial authorization to organ donation. The program initiated with a cohort of 99 requesters from 11 OPOs. Requesters' quarterly authorization rates were monitored for 33 months and their pre-/post-intervention skills in active empathic listening and self-efficacy to request donation were assessed. Read More

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http://dx.doi.org/10.1111/ctr.13488DOI Listing
January 2019

Linking Podcasts With Social Media to Promote Community Health and Medical Research: Feasibility Study.

JMIR Form Res 2018 Oct 24;2(2):e10025. Epub 2018 Oct 24.

Center for Clinical and Translational Science, Mayo Clinic, Rochester, MN, United States.

Background: Linking podcasts with social media is a strategy to promote and disseminate health and health research information to the community without constraints of time, weather, and geography.

Objective: To describe the process of creating a podcast library and promoting it on social media as a strategy for disseminating health and biomedical research topics to the community.

Methods: We used a community and patient engagement in research approach for developing a process to use podcasts for dissemination of health and health research information. Read More

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http://dx.doi.org/10.2196/10025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334680PMC
October 2018
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From Modules to MOOCs: Application of the Six-Step Approach to Online Curriculum Development for Medical Education.

Acad Med 2019 Jan 22. Epub 2019 Jan 22.

B.Y. Chen is director, Faculty Development Programs in Curriculum Development, Johns Hopkins University School of Medicine; and assistant professor, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland. ORCID: http://orcid.org/0000-0002-9905-6180. D.E. Kern is emeritus professor of medicine, past director, Faculty Development Programs in Curriculum Development, Johns Hopkins University School of Medicine, and past director, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland. ORCID: http://orcid.org/0000-0002-9327-6190. R.M. Kearns is director, Online Education, Johns Hopkins University School of Medicine. Baltimore, Maryland. P. Thomas is professor of medicine and vice dean for medical education, Case Western Reserve University School of Medicine, Cleveland, Ohio. M.T. Hughes is assistant professor of medicine, Division of General Internal Medicine; and co-editor, Johns Hopkins Internal Medicine Ambulatory Care Curriculum on PEAC: Physician Education and Assessment Center, Johns Hopkins School of Medicine, Baltimore, Maryland. S. Tackett is assistant professor of medicine, and international medical education director, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland. ORCID: http://orcid.org/0000-0001-5369-7225.

Online curricula can make high-quality health professions education accessible in virtually any setting. They can enhance teaching and learning by both standardizing curricular resources and individualizing curricular experiences. Despite growing demand for and institutional interest in online curricula for medical education, many medical educators lack a framework for online curriculum development. Read More

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http://dx.doi.org/10.1097/ACM.0000000000002580DOI Listing
January 2019

Disarming to disseminate.

Authors:
Ashley York

Nat Rev Microbiol 2019 Mar;17(3):126-127

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-019-0151-3DOI Listing

Quality Improvement Toolkits: Recommendations for Development.

Am J Med Qual 2019 Jan 24:1062860618822102. Epub 2019 Jan 24.

2 VA Greater Los Angeles Healthcare System, Los Angeles, CA.

A burgeoning number of toolkits dedicated to improving health care exist but development guidance is lacking. The authors convened a panel of health care stakeholders, including developers, purchasers, users, funders, and disseminators of toolkits. The panel was informed by a literature review that analyzed 44 publications and 27 toolkits. Read More

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http://dx.doi.org/10.1177/1062860618822102DOI Listing
January 2019
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Silencing Leukocyte Immunoglobulin-Like Receptor A1 in Monocytes Inhibits Inflammation in Mice with Multiple Sclerosis.

Neuroimmunomodulation 2019 Jan 23:1-9. Epub 2019 Jan 23.

Department of Neurology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin,

Objective: Multiple sclerosis (MS), also called disseminated sclerosis or encephalomyelitis disseminate, is an inflammatory disorder in which the insulating covers of brain nerve cells and the spinal cord are impaired. Emerging evidence has highlighted leukocyte immunoglobulin-like receptor A1 (LILRA1) and its ability to suppress the secretion of various inflammatory factors.

Method: During this study, we explored cell viability, apoptosis, and levels of certain inflammatory factors when silencing LILRA1 in cultured spinal cord cells obtained from mice with MS. Read More

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https://www.karger.com/Article/FullText/495625
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http://dx.doi.org/10.1159/000495625DOI Listing
January 2019
4 Reads