10,147 results match your criteria Disseminate and Recurrent Infundibular Folliculitis

Shorter versus longer durations of antibiotic treatment for patients with community-acquired pneumonia: a protocol for a systematic review and meta-analysis.

BMJ Open 2022 Jun 24;12(6):e062428. Epub 2022 Jun 24.

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada

Introduction: Community-acquired pneumonia (CAP), frequently encountered in both outpatient and inpatient settings, is the leading cause of infectious disease-related mortality. While equipoise regarding the optimal duration of antimicrobial therapy to treat CAP remains, recent studies suggest shorter durations of therapy may achieve optimal outcomes. We have therefore planned a systematic review and meta-analysis evaluating the impact of shorter versus longer durations of antibiotic therapy for patients with CAP. Read More

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A comic-based body image intervention for adolescents in semi-rural Indian schools: Study protocol for a randomized controlled trial.

Body Image 2022 Jun 21;42:183-196. Epub 2022 Jun 21.

Centre for Appearance Research, University of the West of England, UK.

Adolescents in India experience body dissatisfaction, however, empirically supported interventions are lacking. This paper describes the protocol for the development, acceptability testing, and cluster randomized controlled trial (RCT) of a six-session comic-based intervention, which aims to improve body image and related outcomes among adolescents in semi-rural Indian schools. If found to be acceptable and effective, UNICEF will disseminate the intervention across schools in eight states of India. Read More

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Involving Caregivers of Autistic Toddlers in Early Intervention: Common Practice or Exception to the Norm?

Am J Speech Lang Pathol 2022 Jun 24:1-16. Epub 2022 Jun 24.

Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.

Purpose: Family-centered practice (FCP) is a core component of early intervention (EI) associated with improved child and family outcomes, but little is known about community-based speech-language pathologists' (SLPs') inclusion of families in EI. Many caregivers of autistic children experience caregiving-related stress, making these intervention principles especially critical to the provision of optimal services. This study aimed to characterize EI SLPs' use of FCP coaching strategies and the quality of caregiver-SLP relationships. Read More

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Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction.

Proc Natl Acad Sci U S A 2022 Jul 24;119(28):e2202370119. Epub 2022 Jun 24.

UMR 5234, Microbiologie Fondamentale et Pathogénicité, CNRS, Université de Bordeaux, 33076 Bordeaux, France.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections initiate in the bronchi of the upper respiratory tract and are able to disseminate to the lower respiratory tract, where infections can cause an acute respiratory distress syndrome with a high degree of mortality in elderly patients. We used reconstituted primary bronchial epithelia from adult and child donors to follow the SARS-CoV-2 infection dynamics. We show that, in epithelia from adult donors, infections initiate in multiciliated cells and spread within 24 to 48 h throughout the whole epithelia. Read More

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Mentoring Undergraduate Research in Mathematical Modeling.

Glenn Ledder

Bull Math Biol 2022 Jun 24;84(8):77. Epub 2022 Jun 24.

Department of Mathematics, University of Nebraska-Lincoln, Lincoln, NE, 68588-0130, USA.

In writing about undergraduate research in mathematical modeling, I draw on my 31 years as a mathematics professor at the University of Nebraska-Lincoln, where I mentored students in honors' theses, REU groups, and research done in a classroom setting, as well as my prior experience. I share my views on the differences between research at the undergraduate and professional levels, offer advice for undergraduate mentoring, provide suggestions for a variety of ways that students can disseminate their research, offer some thoughts on mathematical modeling and how to explain it to undergraduates, and discuss the challenges involved in broadening research participation to include early career students and mid-tier students and how to deliver a research experience in a classroom setting. While different situations pose different challenges, different problems require different approaches, and different experiences lead to different conclusions, it is my hope that my experiences will be of broad value to a wide audience. Read More

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The effectiveness of ERAS guidelines in reducing postoperative pain.

Worldviews Evid Based Nurs 2022 Jun 23. Epub 2022 Jun 23.

University of North Florida, Brooks College of Health, School of Nursing, Nurse Anesthesiology Program, Jacksonville, Florida, USA.

Background: Poorly controlled acute postsurgical pain can promote chronic opioid use and misuse long after the initial surgical procedure. Enhanced recovery after surgery (ERAS) guidelines have shown promise in reducing opioid exposure and minimizing opioid-related side effects.

Aims: The aims of this evidence-based practice (EBP) project were to assess the ERAS literature to guide postoperative pain management practice change at an adult colorectal surgical unit, evaluate the practice change outcomes, and disseminate the findings. Read More

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Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in Midges.

Viruses 2022 Jun 3;14(6). Epub 2022 Jun 3.

Arthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health, Agricultural Research Service, United States Department of Agriculture, Manhattan, KS 66502, USA.

Vesicular stomatitis virus (VSV) primarily infects livestock and is transmitted by direct contact and vectored by midges (Diptera: Ceratopogonidae). Endemic to Central and South America, specific VSV lineages spread northward out of endemic regions of Mexico and into the U.S. Read More

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Prevalence and Molecular Characterisation of Extended-Spectrum Beta-Lactamase-Producing Shiga Toxin-Producing , from Cattle Farm to Aquatic Environments.

Pathogens 2022 Jun 10;11(6). Epub 2022 Jun 10.

Department of Environmental, Water and Earth Sciences, Tshwane University of Technology, Pretoria 0001, South Africa.

Extended-spectrum beta-lactamase (ESBL)-producing bacteria are a major problem for public health worldwide because of limited treatment options. Currently, only limited information is available on ESBL-producing Shiga toxin-producing (STEC) in cattle farms and the surrounding aquatic environment. This study sought to track and characterise ESBL-producing STEC disseminating from a cattle farm into the water environment. Read More

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Lineage Replacement Associated with Fitness Gain in Mammalian Cells and : A Catalyst for Dengue Virus Type 2 Transmission.

Microorganisms 2022 May 26;10(6). Epub 2022 May 26.

Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #06-05-08, Singapore 138667, Singapore.

Shifting of virus serotypes and clade replacement events are known to drive dengue epidemics. However, only a few studies have attempted to elucidate the virus attributes that contribute to such epidemics. In 2007, Singapore experienced a dengue outbreak affecting more than 8000 individuals. Read More

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Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges.

Biomolecules 2022 Jun 4;12(6). Epub 2022 Jun 4.

Grup d'Oncologia Ginecològica i Peritoneal, Institut d'Investigacions Biomédiques Sant Pau, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.

Cancer is one of the main causes of death worldwide. To date, and despite the advances in conventional treatment options, therapy in cancer is still far from optimal due to the non-specific systemic biodistribution of antitumor agents. The inadequate drug concentrations at the tumor site led to an increased incidence of multiple drug resistance and the appearance of many severe undesirable side effects. Read More

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Health Information Orientation Profiles and Their Association with Knowledge of Antibiotic Use in a Population with Good Internet Access: A Cross-Sectional Study.

Antibiotics (Basel) 2022 Jun 4;11(6). Epub 2022 Jun 4.

Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.

Background: Poor knowledge of antibiotic use drives poor antibiotic practices, but little is known about the influence of health information orientation (HIO) on knowledge of antibiotic use in the general public.

Methods: We conducted a nationally-representative population-wide cross-sectional study (November 2020-January 2021), on a proportionately stratified random sample of 2004 Singapore residents aged ≥21 years. Multivariable logistic regression analysis was performed to assess the association between HIO and knowledge of antibiotic use. Read More

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Myths and misconception of COVID-19 among hospital sanitary workers in Pakistan: Efficacy of a training program intervention.

BMC Health Serv Res 2022 Jun 24;22(1):818. Epub 2022 Jun 24.

Department of Environmental Sciences, Quaid-i-Azam University, Faculty of Biological Sciences, Islamabad, 45320, Pakistan.

Objective: Hospital sanitary workers are among the prime source to disseminate information at a massive level, however they received least attention during the pandemic COVID-19. The study was designed to investigate the prevailing myths and misconceptions of the coronavirus pandemic among the sanitary workers of health care system. Further, a systematic training program is devised and tested to demystify the false myths with discerning truth and awareness-raising in hospital sanitary workers. Read More

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Juveniles after Exposure to the Toxic Dinoflagellate : Effects on Fish Viability, Tissue Contamination and Microalgae Survival after Gut Passage.

Toxins (Basel) 2022 Jun 10;14(6). Epub 2022 Jun 10.

MARBEC, Université de Montpellier, CNRS, Ifremer, IRD, 87 Avenue Jean Monnet, 34200 Sète, France.

Pinnatoxins (PnTX) and Portimines (Prtn), two toxins produced by the benthic dinoflagellate , are known to be lethal to mice after intraperitoneal or oral administration. They are also known to accumulate in shellfish such as mussels and clams, but their effect on fish and the upper food chain remains unknown. In this work, juveniles of the fish (Mullet) were exposed to a strain of producing PnTX G and Prtn A. Read More

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Cross-Talk Between the Intestinal Epithelium and Typhimurium.

Front Microbiol 2022 6;13:906238. Epub 2022 Jun 6.

IRSD - Institut de Recherche en Santé Digestive, Université́ de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France.

serovars are invasive gram-negative bacteria, causing a wide range of diseases from gastroenteritis to typhoid fever, representing a public health threat around the world. gains access to the intestinal lumen after oral ingestion of contaminated food or water. The crucial initial step to establish infection is the interaction with the intestinal epithelium. Read More

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The importance of workplace exercise.

Rev Bras Med Trab 2021 Oct-Dec;19(4):523-528. Epub 2021 Dec 30.

Programa de Pós-Graduação em Psicologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.

This narrative review demonstrates the importance of workplace exercise for workers' quality of life and productivity and the reduced number of sick leaves due to repetitive strain injuries/work-related musculoskeletal disorders. To this end, PubMed, SciELO, and CAPES databases were searched, as well as books on the topic. The general objective of this article is to elucidate and disseminate the importance of workplace exercise programs for workers' health and work performance. Read More

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December 2021

A study to investigate the prevalence of headache disorders and migraine among people registered in a health insurance association in Japan.

J Headache Pain 2022 Jun 23;23(1):70. Epub 2022 Jun 23.

Medical Affairs, Otsuka Pharmaceutical Co., Ltd., 463-10 Kagasuno, Kawauchi-cho, Tokushima, 771-0192, Japan.

Background: Migraine is a chronic disease characterized by episodic headache attacks. No recent studies have, however been conducted on the epidemiology of migraine or the treatment landscape in Japan. This study was conducted as a fact-finding survey using medical claims data and an online survey on migraine and headaches, conducted among members of health insurance associations with the objective of gaining an understanding of migraine prevalence and the treatment status in Japan. Read More

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Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors.

J Clin Oncol 2022 Jun 22:JCO2102543. Epub 2022 Jun 22.

Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

JCO Anaplastic oligodendroglial tumors (AOTs) are chemotherapy-sensitive brain tumors. We report the final very long-term survival results from European Organization for the Research and Treatment of Cancer 26951 and Radiation Therapy Oncology Group 9402 phase III trials initiated in 1990s, which both studied radiotherapy with/without neo/adjuvant procarbazine, lomustine, and vincristine (PCV) for newly diagnosed anaplastic oligodendroglial tumors. The median follow-up duration in both was 18-19 years. Read More

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Impact of COVID-19 vaccine misinformation on virality on social media: Content analysis of message themes and writing strategies.

J Med Internet Res 2022 Jun 21. Epub 2022 Jun 21.

Hong Kong Polytechnic University, Kowloon, HK.

Background: Vaccines serve an integral role in containing pandemics, yet vaccine hesitancy is prevalent globally. One key reason for this is the pervasiveness of misinformation on social media. While considerable research attention has been drawn to how exposure to misinformation is closely associated with vaccine hesitancy, little scholarly attention has been given to the investigation or robust theorizing of the various content themes pertaining to antivaccine misinformation about COVID-19 and the writing strategies in which these content themes are manifested. Read More

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Analyzing COVID-19 disinformation on Twitter using the hashtags #scamdemic and #plandemic: Retrospective study.

PLoS One 2022 22;17(6):e0268409. Epub 2022 Jun 22.

Clinical Informatics Center, UT Southwestern Medical Center, Dallas, Texas, United States of America.

Introduction: The use of social media during the COVID-19 pandemic has led to an "infodemic" of mis- and disinformation with potentially grave consequences. To explore means of counteracting disinformation, we analyzed tweets containing the hashtags #Scamdemic and #Plandemic.

Methods: Using a Twitter scraping tool called twint, we collected 419,269 English-language tweets that contained "#Scamdemic" or "#Plandemic" posted in 2020. Read More

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An implementation research programme to support an intravenous iron intervention for pregnant women with moderate and severe anaemia in Malawi: study protocol.

Implement Sci Commun 2022 Jun 21;3(1):68. Epub 2022 Jun 21.

Kamuzu University of Health Sciences, Blantyre, Malawi.

Background: Antenatal iron supplementation is critical to maternal and child health; however, access and adherence to oral iron are inconsistent in many low- and middle-income countries (LMICs). Modern intravenous (IV) iron products have become available in high-income clinical settings and provide an opportunity to deliver high doses of iron in a single-short infusion during pregnancy. However, there is limited knowledge of the drivers and barriers for such an intervention to be effectively delivered and upscaled in LMICs. Read More

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GENESISS 1-Generating Standards for In-Situ Simulation project: a scoping review and conceptual model.

BMC Med Educ 2022 Jun 20;22(1):479. Epub 2022 Jun 20.

Institute of Care Excellence, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Background: In-Situ Simulation (ISS) enables teams to rehearse and review practice in the clinical environment to facilitate knowledge transition, reflection and safe learning. There is increasing use of ISS in healthcare organisations for which patient safety and quality improvement are key drivers. However, the effectiveness of ISS interventions has not yet been fully demonstrated and requires further study to maximise impact. Read More

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Optimizing knowledge and behavioral intention of women and their partners in the perinatal period in South Africa: a randomized control trial study protocol in the Tshwane district, Gauteng province, South Africa.

BMC Public Health 2022 Jun 20;22(1):1224. Epub 2022 Jun 20.

Clinton Health Access Initiative South Africa, 1166 Francis Baard St, Hatfield, Pretoria, 0028, South Africa.

Background: Maternal knowledge that motivates improvements in critical perinatal health behaviors has the potential to significantly reduce maternal and neonatal mortality. However, evidence-based health information often fails to reach mothers and their partners. mHealth video micro-messages, which disseminate evidence-based perinatal health messages, have the potential to address this gap. Read More

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Perceptions of COVID-19 self-testing and recommendations for implementation and scale-up among Black/African Americans: implications for the COVID-19 STEP project.

BMC Public Health 2022 Jun 20;22(1):1220. Epub 2022 Jun 20.

The George Washington University, Milken Institute School of Public Health, 950 New Hampshire Ave, NW, Washington, DC, 20052, USA.

Background: COVID-19 self-testing (ST) is an innovative strategy with the potential to increase the access and uptake of testing and ultimately to limit the spread of the virus. To maximize the uptake and reach of this promising strategy and inform intervention development and scale up, research is needed to understand the acceptability of and willingness to use this tool. This is vital to ensure that Black/African Americans are reached by the Biden-Harris Administration's free national COVID-19 ST program. Read More

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Mapping Chilean clinical research: a protocol for a scoping review and multiple evidence gap maps.

BMJ Open 2022 Jun 20;12(6):e057555. Epub 2022 Jun 20.

Interdisciplinary Centre for Health Studies (CIESAL), Universidad de Valparaíso, Valparaiso, Chile.

Introduction: Clinical research broadly aims to influence decision-making in order to promote appropriate healthcare. Funding agencies should prioritise research projects according to needed research topics, methodological and cost-effectiveness considerations, and expected social value. In Chile, there is no local diagnosis regarding recent clinical research that might inform prioritisation for future research funding. Read More

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Reducing the neurotrauma burden in India- a national mobilization.

World Neurosurg 2022 Jun 17. Epub 2022 Jun 17.

University of Central Florida College of Medicine, Orlando, Florida, USA.

India has one of the highest TBI burdens due to RTA, with 60% of head injuries being attributable to RTA and more than 150000 lives being lost annually due to TBI. These numbers have prompted institutions and organizations at international, national and local levels to mobilize and address this burden through prevention, pre-hospital care and in hospital care. Academic institutions such as the AMC have run local campaigns promoting the wearing of helmets when riding two-wheelers. Read More

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Exploring Whether Addictions Counselors Recommend That Their Patients Use Websites, Smartphone Apps, or Other Digital Health Tools to Help Them in Their Recovery: Web-Based Survey.

Tyler B Wray

JMIR Form Res 2022 Jun 20;6(6):e37008. Epub 2022 Jun 20.

Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, United States.

Background: Hundreds of smartphone apps or websites claiming to help those with addictions are available, but few have been tested for efficacy in changing clinically relevant addictions outcomes. Although most of these products are designed for self-facilitation by users struggling with addictions, counselors and other addictions treatment providers will likely play a critical role in facilitating adoption by integrating their use into counseling or recommending them to their patients. Yet, few studies have explored the practices of addictions counselors in using or recommending addictions-focused digital health tools in their work. Read More

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The Role of Visual Abstracts in the Dissemination of Medical Research.

Ulster Med J 2022 May 15;91(2):67-78. Epub 2022 Jun 15.

James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.

Medical research within the UK has continued to grow, most notably during the COVID-19 pandemic over the last two years, which highlights the importance of disseminating relevant research findings. For all researchers involved in clinical trials and scientific research, the end goal of success is not completed following the publication of the research findings, but ultimately true impact and significance is achieved when such research has a role in developing clinical practice. Each year between 2. Read More

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Innovations in education: A prospective study of storytelling narratives to enhance hepatitis C virus knowledge among substance users.

World J Hepatol 2022 May;14(5):972-983

Department of Biostatistics, University at Buffalo, State University of New York, Buffalo, NY 14214, United States.

Background: Even though substance users have the highest hepatitis C virus (HCV) burden, many lack knowledge about the infection. Lack of knowledge is an important obstacle to pursuing HCV care. Although printed materials are conventionally utilized to disseminate HCV-related knowledge, narrative story-telling videos may be an alternative. Read More

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Perceptions and Attitudes Toward Telemedicine by Clinicians and Patients in Japan During the COVID-19 Pandemic.

Telemed Rep 2021 19;2(1):197-204. Epub 2021 Jul 19.

Tetsuyu Institute Medical Corporation, Tokyo, Japan.

Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide. In Japan, the spread of COVID-19 was recognized and a state of emergency declared in April 2020. In response, public health interventions, such as discouraging people from leaving their homes unnecessarily, were enacted across the country. Read More

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Recognition of esophagitis in endoscopic images using transfer learning.

World J Gastrointest Endosc 2022 May;14(5):311-319

Multidisciplinary Institute of Health, Federal University of Bahia, Vitória da Conquista 45029-094, Bahia, Brazil.

Background: Esophagitis is an inflammatory and damaging process of the esophageal mucosa, which is confirmed by endoscopic visualization and may, in extreme cases, result in stenosis, fistulization and esophageal perforation. The use of deep learning (a field of artificial intelligence) techniques can be considered to determine the presence of esophageal lesions compatible with esophagitis.

Aim: To develop, using transfer learning, a deep neural network model to recognize the presence of esophagitis in endoscopic images. Read More

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