7,743 results match your criteria Dissection Syndromes


Assessment and management of low anterior resection syndrome after sphincter preserving surgery for rectal cancer.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Division of Colorectal Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.

Many patients develop a variety of bowel dysfunction after sphincter preserving surgeries (SPS) for rectal cancer. The bowel dysfunction usually manifests in the form of low anterior resection syndrome (LARS), which has a negative impact on the patients' quality of life. This study reviewed the LARS after SPS, its mechanism, risk factors, diagnosis, prevention, and treatment based on previously published studies. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000852DOI Listing

Acute Coronary Syndrome in Women: An Overview.

Tex Heart Inst J 2020 Apr;47(2):128-129

Department of Cardiology, Texas Heart Institute, Houston, Texas 77030.

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http://dx.doi.org/10.14503/THIJ-19-7077DOI Listing

Combined cataract surgery and lamellar endothelial keratoplasty in iridocorneal endothelial syndrome.

Arch Soc Esp Oftalmol 2020 Jun 25. Epub 2020 Jun 25.

Departamento de Oftalmología, Hospital Clínico San Carlos, Madrid, España.

The case is reported of a 59-year-old woman, who reported decreased visual acuity (VA) in the left eye (LE). On examination, a corrected VA of finger count/ 30cm was observed in LE. Corneal oedema and folds in the Descemet's membrane were observed using the slit lamp. Read More

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http://dx.doi.org/10.1016/j.oftal.2020.05.022DOI Listing

Tarsal tunnel syndrome caused by posterior facet talocalcaneal coalition: A case report.

Medicine (Baltimore) 2020 Jun;99(26):e20893

Department of Orthopaedic Surgery, Soonchunhyang University Hospital Cheonan, Dongam-gu, Cheonan.

Rationale: Tarsal tunnel syndrome (TTS) is a compressive neuropathy of the posterior tibial nerve and its branches. Tarsal coalition is defined as a fibrous, cartilaginous, or osseous bridging of 2 or more tarsal bones. TTS with tarsal coalition is uncommon. Read More

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http://dx.doi.org/10.1097/MD.0000000000020893DOI Listing

"Step-by-step" principles of safe laparoscopic approach with technical details in "median arcuate ligament syndrome".

Authors:
Selçuk Gülmez

Ulus Travma Acil Cerrahi Derg 2020 Jun;26(4):642-646

Department of Gastroenterological Surgery, University of Health Sciences, Kartal Koşuyolu High Specialized Training and Research Hospital, İstanbul-Turkey.

The median arcuate ligament syndrome (MALS) is a rare cause of postprandial pain and weight loss. The median arcuate ligament (MAL) is a fibrous band of the diaphragmatic crura. Abnormally downward located MAL or high take off of the celiac artery result in external compression the celiac trunk. Read More

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http://dx.doi.org/10.14744/tjtes.2019.61559DOI Listing

Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.

J Pediatr 2020 Jul;222:213-220.e5

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; Departments of Pharmacology and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN.

Objective: To test whether variants in ADRB1 and CYP2C9 genes identify subgroups of individuals with differential response to treatment for Marfan syndrome through analysis of data from a large, randomized trial.

Study Design: In a subset of 250 white, non-Hispanic participants with Marfan syndrome in a prior randomized trial of atenolol vs losartan, the common variants rs1801252 and rs1801253 in ADRB1 and rs1799853 and rs1057910 in CYP2C9 were analyzed. The primary outcome was baseline-adjusted annual rate of change in the maximum aortic root diameter z-score over 3 years, assessed using mixed effects models. Read More

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http://dx.doi.org/10.1016/j.jpeds.2020.03.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323908PMC

Intracranial vessel wall MR imaging of an intradural vertebral artery dissection.

Clin Imaging 2020 Jun 17;68:108-110. Epub 2020 Jun 17.

University of Pennsylvania Health Systems (UPHS), 3400 Spruce Street, Philadelphia, PA 19104, USA.

Diagnosis of intracranial arterial dissections can be challenging due to the wide spectrum of imaging presentations. High-resolution vessel wall MR imaging can be a useful adjunct to conventional lumen-based imaging techniques for diagnosing arterial dissections. We present a case of a 37-year-old male with a history of a Wolff-Parkinson-White syndrome presenting with acute onset of nausea, vertigo, and left body hemisensory loss of pain and temperature. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.06.024DOI Listing

A 'parachute effect' mockingly sealing a spontaneous coronary artery dissection: what we have learnt from intravascular imaging.

Future Cardiol 2020 Jun 25. Epub 2020 Jun 25.

Interventional cardiology, S Antonio Abate Hospital, Erice, TP, Italy.

Spontaneous coronary artery dissection is often underdiagnosed. It accounts for a certain amount of acute coronary syndromes. Intravascular imaging, either intravascular ultrasound or optical coherence tomography, represents a relevant ally for interventional cardiologist. Read More

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http://dx.doi.org/10.2217/fca-2019-0068DOI Listing

Familial Clustering of Aortic Size, Aneurysms, and Dissections in the Community.

Circulation 2020 Jun 25. Epub 2020 Jun 25.

Boston University's and National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA; Department of Medicine, Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA; Department of Cardiology, Herlev and Gentofte Hospital, Gentofte, Denmark.

Ruptured aortic aneurysm and aortic dissections are potentially preventable disorders associated with high mortality. Screening of individuals at risk may translate into elective surgical interventions and lowered mortality. It is uncertain if the risk of aortic dilation of varying degrees aggregates within families. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045990DOI Listing

Incidental intrathorcic schwannoma post upper respiratory tract infection associated with Horner's syndrome: A case report.

Respir Med Case Rep 2020 10;30:101126. Epub 2020 Jun 10.

Guthrie Robert Packer Hospital, USA.

Background: Schwannomas may remain asymptomatic, and may be discovered incidentally.

Case Presentation: Here we describe a case of a young female complaining of upper respiratory tract symptoms who was incidentally found to have an intrathoracic neurogenic tumor consistent with schwannoma associated with Horner's syndrome. Biopsy of the tumor revealed S100, BCL-2 and CD 99+ compatible with schwannoma. Read More

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http://dx.doi.org/10.1016/j.rmcr.2020.101126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303989PMC

Managing Malperfusion Syndrome in Acute Type A Aortic Dissection with Previous Cardiac Surgery.

Ann Thorac Surg 2020 Jun 19. Epub 2020 Jun 19.

Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. Electronic address:

Background: Patients with acute type A aortic dissection (ATAAD) with a previous cardiac surgery (PCS) and malperfusion syndrome (MPS) are extremely difficult to manage and have poor outcomes.

Methods: From 1996-2018, 668 patients underwent emergent open aortic repair or endovascular fenestration/stenting for MPS for an ATAAD, including those with PCS (PCS, n=64) and those without PCS (No-PCS, n=604). The groups were further divided into PCS+MPS, PCS+No-MPS, No-PCS+MPS, and No-PCS+No-MPS groups. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.132DOI Listing

Complete atrioventricular block as an initial manifestation of aortic dissection: A case report.

Cir Cir 2020 ;88(4):511-513

Unidad Coronaria, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México.

The right coronary artery involvement occurs in 1-2% of aortic dissection and may cause atrioventricular (AV) block due to obstruction of blood supply to the AV node. A 59-year-old man with a history of hypertension presented to the emergency department with chest pain and complete AV block. After the diagnostic approach, aortic dissection Stanford A was diagnosed. Read More

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http://dx.doi.org/10.24875/CIRU.19001232DOI Listing
January 2020

First Bite Syndrome Following Rhytidectomy: A Case Report.

Ann Otol Rhinol Laryngol 2020 Jun 21:3489420936713. Epub 2020 Jun 21.

Otolaryngology-Head and Neck Surgery, Madigan Army Medical Center, Tacoma, WA.

Background: First bite syndrome (FBS) is a known complication of parotid gland resection, parapharyngeal space dissection, and cervical sympathetic chain injury. It can be described as severe cramping or spasms in the parotid region triggered by the first bite of a meal, with the pain lessening during each subsequent bite. Although dissection for a rhytidectomy is in the vicinity of the parotid parenchyma, face-lift is not typically characterized as a procedure that can lead to FBS. Read More

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http://dx.doi.org/10.1177/0003489420936713DOI Listing

Implementation of an aortic dissection CT protocol with clinical decision support aimed at decreasing radiation exposure by reducing routine abdominopelvic imaging.

Clin Imaging 2020 Jun 8;67:108-112. Epub 2020 Jun 8.

Department of Radiology, Montefiore Medical Center, Bronx, NY 10467, United States; Albert Einstein College of Medicine, Bronx, NY 10467, United States; Department of Medicine, Montefiore Medical Center, Bronx, NY 10467, United States.

Patients suspected of having an acute aortic syndrome in the ED typically undergo CT of the chest/abdomen/pelvis. However, the overwhelming majority of these exams are negative. With the help of clinical decision support, we implemented a new radiologist monitored 'aortic dissection screening protocol' that forgoes routine abdominopelvic imaging in order to reduce radiation dose without compromising diagnostic accuracy. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.06.005DOI Listing

[Late occurrence of pulmonary embolsim in SARS-CoV-2 pneumonia: a case series].

G Ital Cardiol (Rome) 2020 Jul;21(7):523-525

Dipartimento di Anestesiologia e Terapia Intensiva, Ospedale Guglielmo da Saliceto, Piacenza.

Several studies suggested that the acute phase of SARS-CoV-2 infection may be associated with a hypercoagulable state and increased risk for venous thromboembolism but the incidence of thrombotic complications in the late phase of the disease is currently unknown. The present article describes three cases of patients with SARS-CoV-2 pneumonia and late occurrence of pulmonary embolism. Case 1: a 57-year-old man diagnosed with pulmonary embolism and type B aortic dissection after 12 days from SARS-CoV-2 pneumonia. Read More

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http://dx.doi.org/10.1714/3386.33638DOI Listing

Spontaneous Coronary Artery Dissection in a Patient With COVID-19.

JACC Cardiovasc Interv 2020 06 8;13(12):e107-e108. Epub 2020 Apr 8.

University of Lyon, CREATIS UMR5220, INSERM U1044, INSA-15, Lyon, France; Cardiology Department, Hôpital Croix-Rousse, Hospices Civils de Lyon, Lyon, France; Cardiology Department, Hôpital Lyon Sud, Hospices Civils de Lyon, Lyon, France.

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http://dx.doi.org/10.1016/j.jcin.2020.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142671PMC

Early and mid-term results of endovascular treatment of thoracic aorta diseases: a single-center experience.

Semin Vasc Surg 2020 Mar 3;32(3-4):111-116. Epub 2020 Apr 3.

Unit of Vascular and Endovascular Surgery, Grande Ospedale Metropolitano, Bianchi-Melacrino-Morelli, Via Giuseppe Melacrino 21-89124, Reggio Calabria, Italy.

We conducted an analysis to assess early and mid-term outcomes of patients after thoracic endovascular aortic repair (TEVAR) for type B thoracic aorta dissection, descending thoracic aneurysm, or traumatic aortic transection. From January 2016 through December 2018, twenty-seven patients (23 male, 4 female, mean age of 57 years) affected by type B dissection (n = 13 [48.2%]), thoracic aneurysm (n = 9 [33. Read More

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http://dx.doi.org/10.1053/j.semvascsurg.2020.03.002DOI Listing
March 2020
1.583 Impact Factor

Spontaneous coronary artery dissection in young female acute coronary syndrome patients: a single-centre retrospective cohort study.

Acta Cardiol 2020 Jun 19:1-5. Epub 2020 Jun 19.

Cardiology Department, ZNA Hartcentrum - ZNA Middelheim, Antwerp, Belgium.

Spontaneous coronary artery dissection (SCAD) is an unusual cause of acute coronary syndrome (ACS), rapidly gaining recognition over the last decade. SCAD occurs predominantly in young, otherwise healthy women and coronary angiogram often lacks typical (atherosclerotic) features. Therefore, SCAD remains notably underdiagnosed. Read More

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http://dx.doi.org/10.1080/00015385.2020.1778373DOI Listing

Laparoscopic Enucleation of Hepatic Cysts Reduces the Recurrence of Nonparasitic Hepatic Cysts.

J Laparoendosc Adv Surg Tech A 2020 Jun 18. Epub 2020 Jun 18.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Standard treatments for nonparasitic hepatic cysts (NPHCs) include laparoscopic deroofing (LD), percutaneous aspiration, and alcohol sclerotherapy. However, these treatments have limitations. LD and alcohol sclerotherapy, for example, fail to prevent NPHC recurrences, although alcohol sclerotherapy is satisfactorily effective in treating small cysts (diameter <5 cm), which do not usually need treatment. Read More

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http://dx.doi.org/10.1089/lap.2019.0829DOI Listing

Is the frozen elephant trunk technique justified for chronic type A aortic dissection in Marfan syndrome?

Ann Cardiothorac Surg 2020 May;9(3):197-208

Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.

Background: Chronic type A aortic dissection (cTAAD) in Marfan syndrome (MFS) is rare. Surgical experience is limited and the role of frozen elephant trunk (FET) technique remains undefined. We seek to evaluate the safety and efficacy of the total arch replacement (TAR) and FET technique for cTAAD in MFS. Read More

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http://dx.doi.org/10.21037/acs.2020.03.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298250PMC

Laparoscopic repair of Morgagni hernia in children.

Ann Med Surg (Lond) 2020 Aug 30;56:7-10. Epub 2020 May 30.

Harran University, Clinic of Pediatric Surgery, Şanlıurfa, Turkey.

Aim: We aimed to present our laparoscopic treatment experience in Morgagni hernia repair.

Methods: The patients who underwent laparoscopic surgery with diagnosis of Morgagni hernia between 2016 and 2019 were evaluated retrospectively.

Results: Their mean age at diagnosis was 4,1 ± 2,6 years (1 year-13 years). Read More

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http://dx.doi.org/10.1016/j.amsu.2020.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292882PMC

Ruptured Aortic Aneurysm and Dissection Related Death: an Autopsy Database Analysis.

Pathol Oncol Res 2020 Jun 16. Epub 2020 Jun 16.

Heart and Vascular Center, Department of Vascular and Endovascular Surgery, Semmelweis University, Városmajor u. 68, Budapest, 1122, Hungary.

Acute aortic catastrophes (AAC), mainly ruptured aneurysms and dissections, lead all other vascular conditions in morbidity and mortality, even if intervention occurs. The aim of our study was to give a descriptive overview of the demographic and pathological characteristics of AAC. Between 1994 and 2013, 80,469 autopsies were performed at Semmelweis University hospitals in Budapest. Read More

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http://dx.doi.org/10.1007/s12253-020-00835-xDOI Listing

Long-term clinical outcomes of losartan in patients with Marfan syndrome: follow-up of the multicentre randomized controlled COMPARE trial.

Eur Heart J 2020 Jun 15. Epub 2020 Jun 15.

Department of Cardiology, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Aims: The COMPARE trial showed a small but significant beneficial effect of 3-year losartan treatment on aortic root dilatation rate in adults with Marfan syndrome (MFS). However, no significant effect was found on clinical endpoints, possibly due to a short follow-up period. The aim of the current study was therefore to investigate the long-term clinical outcomes after losartan treatment. Read More

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http://dx.doi.org/10.1093/eurheartj/ehaa377DOI Listing

Postpartum aortic dissection diagnosed by point-of-care ultrasound in the emergency department: A case study.

Australas Emerg Care 2020 Jun 13. Epub 2020 Jun 13.

Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA.

Aortic dissection is a rare but clinically significant cause of chest pain in the emergency department (ED). While classic risk factors include advanced age, male sex, and tobacco use, pregnancy is also an independent and easily overlooked risk factor. Aortic dissection carries both high maternal and fetal morbidity and mortality. Read More

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http://dx.doi.org/10.1016/j.auec.2020.04.003DOI Listing

Devices for thoracic endovascular aortic repair of type B aortic dissection: is there any chance for Marfan syndrome?

Expert Rev Med Devices 2020 Jun 16. Epub 2020 Jun 16.

Marfan Center; Lancisi Cardiovascular Center, Polytechnic University of Marche , Ancona, Italy.

Introduction: Type B aortic dissection (TBAD) is a threatening event that may lead to death for aortic rupture or multivisceral malperfusion in the acute phase and offers a poor prognosis for long term survivors. Thoracic endovascular aortic repair (TEVAR) has become the preferential therapy in acute and chronic complicated cases for its less invasivity compared to open surgery. However TEVAR is still encumbered by a significant number of reinterventions, caused by aortic neck aneurysmal degeneration, endoleaks and stent-graft induced new entry (SINE). Read More

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http://dx.doi.org/10.1080/17434440.2020.1782735DOI Listing

[A Case of Acute Aortic Dissection Following Intrapartum in a Patient with Marfan ' s Syndrome].

Sichuan Da Xue Xue Bao Yi Xue Ban 2020 May;51(3):438-440

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

A 33-year-old woman was admitted at 34 weeks after embryo transfer and over 5 d of cutaneous pruritus. Over 2 years ago, the patient had a third-generation test tube baby due to Marfan's syndrome and gave birth to a live baby girl at full term. This time, the glucose tolerance test during the prenatal examination indicated that the patient was with gestational diabetes, and the blood glucose fluctuated within the normal range after the medical nutrition management and exercise control. Read More

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http://dx.doi.org/10.12182/20200560603DOI Listing

Effect of prophylactic closure on adverse events after colorectal endoscopic submucosal dissection: A meta-analysis.

J Gastroenterol Hepatol 2020 Jun 15. Epub 2020 Jun 15.

Department of Gastroenterology, First Hospital of Jilin University, ChangChun, China.

Background And Aim: Endoscopic submucosal dissection (ESD) has a high en bloc resection rate and is widely performed for large colorectal lesions. However, colorectal ESD is associated with a high frequency of adverse events (AEs), and the efficacy of prophylactic endoscopic closure after ESD for preventing AEs is still controversial. This meta-analysis was conducted to assess the efficacy of closure on AEs following colorectal ESD. Read More

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http://dx.doi.org/10.1111/jgh.15148DOI Listing

Dissection of Clinical and Gene Expression Signatures of Familial versus Multifactorial Chylomicronemia.

J Endocr Soc 2020 Jun 15;4(6):bvaa056. Epub 2020 May 15.

Lipidology Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal and ECOGENE-21 Clinical and Translational Research Center, Chicoutimi, Quebec, Canada.

Familial chylomicronemia syndrome (FCS) is a rare disorder associated with chylomicronemia (CM) and an increased risk of pancreatitis. Most individuals with CM do not have FCS but exhibit multifactorial CM (MCM), which differs from FCS in terms of risk and disease management. This study aimed to investigate clinical and gene expression profiles of FCS and MCM patients. Read More

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http://dx.doi.org/10.1210/jendso/bvaa056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278277PMC

Identification of a Pathogenic Variant in a Patient With Loeys-Dietz Syndrome.

Front Genet 2020 27;11:479. Epub 2020 May 27.

Department of Cardiology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Loeys-Dietz syndrome (LDS) is a rare connective tissue genetic disorder that is caused by a pathogenic variant in genes of transforming growth factor (TGF) beta receptor 1 (), , mothers against decapentaplegic homolog 2 (), , , or . It is characterized by aggressive vascular pathology, aneurysms, arterial tortuosity, bifid uvula, hypertelorism, and cleft palate. Here we present a 42-year-old female patient with LDS. Read More

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http://dx.doi.org/10.3389/fgene.2020.00479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266969PMC

Anti-Ri-associated paraneoplastic ophthalmoplegia-ataxia syndrome in a woman with breast cancer: a case report and review of the literature.

J Med Case Rep 2020 Jun 12;14(1):67. Epub 2020 Jun 12.

Department of Medical and Surgical Sciences, U.O. of General Surgery, University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.

Background: Breast cancer is the most common cancer in women. However, in the management of breast cancer, paraneoplastic neurological syndromes represent a diagnostic and therapeutic challenge. The diagnosis of paraneoplastic neurological syndromes is difficult due to the heterogeneity of symptoms, the timing of presentation, and the absence of antibodies, and it generally occurs before the diagnosis of breast cancer in 80% of patients who develop paraneoplastic neurological syndromes. Read More

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http://dx.doi.org/10.1186/s13256-020-02410-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291432PMC

Autologous fat grafting efficacy in treating PostMastectomy pain syndrome: A prospective multicenter trial of two Senonetwork Italia breast centers.

Breast J 2020 Jun 10. Epub 2020 Jun 10.

Plastic Surgery Unit, Department of Medical Biotechnology and Translational Medicine BIOMETRA, Humanitas Clinical and Research Hospital, Reconstructive and Aesthetic Plastic Surgery School, University of Milan, Milan, Italy.

Postmastectomy pain syndrome (PMPS) represents a common complication following breast surgery defined as a chronic neuropathic pain located in the front of the chest, in the axilla and in the upper arm that for more than 3 months after surgery. Several medications prove to be ineffective while autologous fat grafting revealed to be an innovative solution in the treatment of neuropathic pain syndromes based on retrospective studies. For this reason, we performed a prospective multicenter trial to reduce the memory bias and further increase the evidence of the results. Read More

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http://dx.doi.org/10.1111/tbj.13923DOI Listing

[Surgical treatment of carpal tunnel syndrome: open release of the flexor retinaculum and hypothenar fat flap for revision surgery].

Oper Orthop Traumatol 2020 Jun 10;32(3):219-235. Epub 2020 Jun 10.

Handchirurgie, Vulpius Klinik, Vulpiusstr. 29, 74906, Bad Rappenau, Deutschland.

Objective: Decompression of the median nerve by complete release of the flexor retinaculum and the distal antebrachial fascia. In the case of revision surgery providing of a scar-free covering of the median nerve, if necessary.

Indications: Carpal tunnel release is indicated for symptomatic patients with painful paraesthesia or neurological deficits after adequate diagnostic evaluation. Read More

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http://dx.doi.org/10.1007/s00064-020-00662-yDOI Listing

Myocardial infarction with non-obstructive coronary arteries: what is the prognosis?

Eur Heart J Suppl 2020 Jun 30;22(Suppl E):E40-E45. Epub 2020 Mar 30.

Universita' Vita-Salute e Ospedale San Raffaele, IRCCS Milano, Italy.

Myocardial infarction in the absence of obstructive coronary stenosis (MINOCA) is a syndrome with several causes, characterized by clinical evidence of myocardial infarction and coronary angiographically normal or almost normal (stenosis ≤50%). MINOCAs represent about 10% of acute coronary syndromes. The causes of MINOCA are manifold and can be classified on the basis of the mechanism in epicardial (unstable plaque not manifested by angiography, epicardial spasm and coronary dissection) or microvascular. Read More

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http://dx.doi.org/10.1093/eurheartj/suaa057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270909PMC

Bow hunter syndrome: A rare yet important etiology of posterior circulation stroke.

J Clin Neurosci 2020 Jun 7. Epub 2020 Jun 7.

Division of Neurology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

A6-year-oldgirl presented with acute-onset headache andfluctuating right-sided weakness.HerPedNIHSSwas13. Brain MRI/MRA showed acute pontine arterial ischemic stroke(AIS)and remote right cerebellar and thalamic infarcts. Read More

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http://dx.doi.org/10.1016/j.jocn.2020.04.110DOI Listing

Male-female differences in quality of life and coping style in patients with Marfan syndrome and hereditary thoracic aortic diseases.

J Genet Couns 2020 Jun 10. Epub 2020 Jun 10.

Department of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.

Hereditary thoracic aortic diseases (HTAD) such as Marfan syndrome (MFS) affect multiple organ systems and provide a risk of acute aortic dissection, which causes lifelong uncertainties. Although health-related quality of life (HRQOL) was found to be reduced in HTAD patients, no studies have evaluated male-female-specific aspects of HRQOL and coping in this population. This study aims to evaluate HRQOL in HTAD patients compared to the general population; assess male-female differences in HRQOL and factors associated with HRQOL; evaluate coping styles in male and female HTAD patients and identify factors associated with acceptance. Read More

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http://dx.doi.org/10.1002/jgc4.1288DOI Listing

Germline TET2 Loss-Of-Function Causes Childhood Immunodeficiency And Lymphoma.

Blood 2020 Jun 9. Epub 2020 Jun 9.

Department of Clinical Immunology and Allergy, St James's University Hospital, United Kingdom.

Molecular dissection of inborn errors of immunity can help to elucidate the nonredundant functions of individual genes. We studied three children with an immunodysregulatory syndrome of susceptibility to infection, lymphadenopathy, hepatosplenomegaly, developmental delay, autoimmunity and lymphoma of either B- (n=2) or T-cell (n=1) origin. All three showed early autologous T-cell reconstitution following allogeneic hematopoietic stem cell transplantation. Read More

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http://dx.doi.org/10.1182/blood.2020005844DOI Listing

Pregnancy and cardiovascular disease.

Nat Rev Cardiol 2020 Jun 9. Epub 2020 Jun 9.

Department of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands.

Cardiovascular disease complicates 1-4% of pregnancies - with a higher prevalence when including hypertensive disorders - and is the leading cause of maternal death. In women with known cardiovascular pathology, such as congenital heart disease, timely counselling is possible and the outcome is fairly good. By contrast, maternal mortality is high in women with acquired heart disease that presents during pregnancy (such as acute coronary syndrome or aortic dissection). Read More

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http://dx.doi.org/10.1038/s41569-020-0390-zDOI Listing

Viscodelamination of Localized Retrolental Plaques During Lens-Sparing Vitrectomy in Eyes With Pediatric Tractional Vitreoretinopathy.

Retina 2020 Jun 8. Epub 2020 Jun 8.

Department of Ophthalmology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Purpose: To report viscodelamination of localized retrolental plaques during lens-sparing vitrectomy in eyes with pediatric tractional vitreoretinopathy.

Methods: Viscodelamination of retrolental plaques was performed during 23-gauge lens-sparing vitrectomy in 11 eyes from 11 children with a median age (range) of 12 (4-58) months. There were five eyes with Stage 4 familial exudative vitreoretinopathy, one eye with Stage 4B retinopathy of prematurity, and five eyes with anterior-posterior persistent fetal vasculature syndrome. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002834DOI Listing
June 2020
3.243 Impact Factor

A Surgical View of Anatomy: Perspectives from Students and Instructors.

Anat Sci Educ 2020 Jun 8. Epub 2020 Jun 8.

Harvard Medical School, Harvard University, Boston, Massachusetts, United States.

As curricular emphasis on anatomy in undergraduate medical education continues to evolve, new approaches to anatomical education are urgently needed to prepare medical students for residency. A surgical anatomy class was designed for third- and fourth-year medical students to explore important anatomical relationships by performing realistic surgical procedures on anatomical donors. Under the guidance of both surgeons and anatomists, students in this month-long elective course explored key anatomical relationships through performing surgical approaches, with the secondary benefit of practicing basic surgical techniques. Read More

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http://dx.doi.org/10.1002/ase.1988DOI Listing

IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation.

Case Rep Oncol 2020 Jan-Apr;13(1):462-467. Epub 2020 Apr 30.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17. Read More

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http://dx.doi.org/10.1159/000506975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250377PMC

Imaging Cardiovascular Emergencies: Real World Clinical Cases.

Heart Fail Clin 2020 Jul;16(3):331-346

Division of Cardiac Rehabilitation - Echo Lab, A Cardarelli Hospital, Naples, Italy. Electronic address:

Cardiovascular emergencies represent life-threatening conditions requiring a high index of clinical suspicion. In an emergency scenario, a simple stepwise biomarker/imaging diagnostic algorithm may help prompt diagnosis and timely treatment along with related improved outcomes. This article describes several clinical cases of cardiovascular emergencies, such as coronary stent thrombosis-restenosis, takotsubo syndrome, acute myocarditis, massive pulmonary embolism, type A acute aortic dissection, cardiac tamponade, and endocarditis. Read More

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http://dx.doi.org/10.1016/j.hfc.2020.03.003DOI Listing

Acute Aortic Syndromes: Diagnostic and Therapeutic Pathways.

Heart Fail Clin 2020 Jul;16(3):305-315

Department of Cardiovascular Surgery, Faculty of Medicine, University Heart Center Freiburg, Albert-Ludwigs-University of Freiburg, Breisacher Str. 86, Freiburg 79110, Germany.

Acute aortic syndromes are life-threatening medical conditions that include classic acute aortic dissection (AAD), aortic intramural hematoma, penetrating aortic ulcer, and even aortic pseudoaneurysm and traumatic aortic injury. The European Society of Cardiology has designed a multiparametric diagnostic algorithm to provide stepwise diagnosis. All patients with AAD should receive aggressive medical therapy to control blood pressure and heart rate. Read More

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http://dx.doi.org/10.1016/j.hfc.2020.03.002DOI Listing

Endocrine surgery during COVID-19 pandemic: do we need an update of indications in Italy?

Endocrine 2020 06 4;68(3):485-488. Epub 2020 Jun 4.

Division of Endocrine Surgery, "Agostino Gemelli" School of Medicine, University Foundation Polyclinic, Catholic University of the Sacred Heart, Rome, Italy.

The ongoing spread of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a significant threat to global health. As the coronavirus outbreak began spreading, hospitals were forced to relocate resources to treat the growing number of COVID-19 patients. As a consequence, doctors across the country canceled tens of thousands of nonurgent surgeries. Read More

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http://dx.doi.org/10.1007/s12020-020-02357-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270156PMC
June 2020
3.527 Impact Factor

Psychological and clinical characteristics of female patients with spontaneous coronary artery dissection.

Neth Heart J 2020 Jun 4. Epub 2020 Jun 4.

Department of Cardiology, Radboud University Medical Centre, Nijmegen, The Netherlands.

Aims: Spontaneous coronary artery dissection (SCAD) is increasingly recognised as a cause of myocardial infarction, but psychological characteristics of patients with SCAD have not yet been extensively investigated. We assessed the prevalence of a broad range of psychological and clinical factors, and their inter-relationships in patients with a history of SCAD. Furthermore, we investigated whether specific clusters of patients with SCAD can be identified. Read More

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http://dx.doi.org/10.1007/s12471-020-01437-7DOI Listing

Changes in the diagnosis and management of acute aortic syndrome and associated mortality in the last 20 years.

Rev Esp Cardiol (Engl Ed) 2020 Jun 1. Epub 2020 Jun 1.

Servicio de Cardiología, Hospital Universitari Vall d'Hebron, Institut de Recerca Vall d'Hebron (VHIR), Barcelona, CIBER-CV, Spain.

Introduction And Objectives: Mortality is high in acute aortic syndrome (AAS), which therefore requires early treatment. This study aimed to analyze changes in the diagnosis and treatment of AAS over 20 years at our center.

Methods: From 1999 to 2018, 451 patients diagnosed with AAS (336 men; mean age, 60. Read More

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http://dx.doi.org/10.1016/j.rec.2020.02.015DOI Listing

Acute complicated type B aortic dissection during the New York City COVID-19 surge.

J Card Surg 2020 Jun 4. Epub 2020 Jun 4.

Department of Surgery, Maimonides Medical Center, Brooklyn, New York.

The impact of the coronavirus disease 2019 (COVID-19) pandemic in New York City (NYC) is dramatic. COVID-19 cases surged, hospitals expanded to meet capacity, and NYC remains the global epicenter of this pandemic. During this unprecedented time, a young woman with known Marfan syndrome presented with an acute complicated type B aortic dissection to our Aortic Center. Read More

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http://dx.doi.org/10.1111/jocs.14678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300946PMC

Patients who report cording after breast cancer surgery are at higher risk of lymphedema: Results from a large prospective screening cohort.

J Surg Oncol 2020 Jun 4. Epub 2020 Jun 4.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.

Objectives: To identify the association between cording and breast cancer-related lymphedema (BCRL); describe time course, location, symptoms and functional impairments.

Methods: A total of 1181 patients were prospectively screened for BCRL after breast cancer (BC) surgery, including patient-reported outcome measures (4193) and perometric arm volume measurements (BCRL defined as relative or weight-adjusted volume change [RVC or WAC] ≥10% ≥3 months postoperatively).

Results: A total of 374/1181 patients (31. Read More

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http://dx.doi.org/10.1002/jso.25944DOI Listing

[Spontaneous coronary artery dissection : primum nihil nocere].

Rev Med Suisse 2020 Jun;16(696):1153-1158

Service de cardiologie, HUG, 1211 Genève 14.

Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome, myocardial infarction and sudden cardiac death, among young patient with little/no traditional cardiovascular risk factors. Historically SCAD was considered as a rare pathology, associated primarily with pregnancy and the peripartum period. In recent years, SCAD diagnosis improved thanks to data derived from large registries, thanks to the increased use of diagnostic coronary angiography and the availability of intracoronary imaging. Read More

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Manual deep anterior lamellar keratoplasty after partial unintentional full-thickness trephination.

Eur J Ophthalmol 2020 Jun 3:1120672120932108. Epub 2020 Jun 3.

Clinica degli Occhi Sarnicola, Grosseto, Italy.

Purpose: The aim of this study was to describe a surgical technique to perform deep anterior lamellar keratoplasty (DALK) despite inadvertent full thickness trephination in one quadrant.

Methods: Case report of a 19-year-old boy who underwent DALK for visually significant post-infectious stromal scar in his left eye. An unintentional full thickness trephination occurred in the upper-nasal quadrant at the beginning of the surgery. Read More

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http://dx.doi.org/10.1177/1120672120932108DOI Listing

Fluoroquinolone-Associated Type A Aortic Dissection in Alpha-1 Anti-Trypsin Deficiency.

Ann Thorac Surg 2020 May 31. Epub 2020 May 31.

Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary.

Fluroquinolone (FQ) antibiotics have come under increased scrutiny given their recent association with aortic events. While judicious use has been urged in select patient populations such as those with Marfan and Ehlers-Danlos syndromes that have a known predisposition for aortopathy, other at-risk patient populations may remain. Here we describe the atypical delayed-presentation of a type A aortic dissection in a patient with alpha-1 anti-trypsin (A1AT) deficiency and longstanding FQ exposure. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.044DOI Listing