2,869 results match your criteria Diskitis

[Spondylodiscitis and epidural abscesses].

Radiologe 2021 Mar 11;61(3):275-282. Epub 2021 Feb 11.

Abteilung Neuroradiologie, Zentrum für Bildgebung, Kantonsspital Baden AG, Im Ergel 1, 5404, Baden, Schweiz.

Clinical/methodological Problem: Spondylodiscitis is an inflammation of the intervertebral disc, which in adults is generally associated with spondylitis of the adjacent vertebrae. It often presents clinically with nonspecific symptoms such as back or neck pain. It may be caused by various pathogens, especially bacteria. Read More

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Management of post-operative discitis following discectomy in a tertiary-level hospital.

J Orthop Surg (Hong Kong) 2021 Jan-Apr;29(1):2309499020988213

Department of Orthopaedic surgery, 468778Dhaka Community Medical College and Hospital, Dhaka, Bangladesh.

Purpose: To perform retrospective analysis of 75 post-operative disc space infections after open lumbar discectomy (OLD) and to assess the outcome of their medical and surgical management in a tertiary-level hospital.

Methods: Records of 50 men and 25 women aged 26-65 (mean, 42.53) years who underwent treatment for post-operative discitis (POD) after single level OLD at L3-4 (n = 8), L4-5 (n = 42), L5-S1 (n = 25) level. Read More

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February 2021

Fatal epidural abscess from diabetic foot disease.

Endocrinol Diabetes Metab Case Rep 2021 Feb 9;2021. Epub 2021 Feb 9.

Department of Endocrinology and Diabetes, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

Summary: Infection is a common complication of advanced diabetic foot disease, increasing the risk of acute admission and amputation. It is less well-known that foot ulceration and osteomyelitis may cause bacteraemia-associated hematogenous seeding and subsequent epidural abscess formation. Here we describe the case of a 57-year-old woman with known diabetic foot ulcer with underlying osteomyelitis admitted with backpain in the absence of trauma. Read More

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February 2021

Severe Group C Streptococcus infection in a veterinarian.

IDCases 2021 22;23:e01036. Epub 2021 Jan 22.

Medical College of Wisconsin, Infectious Disease Department, 8701 W Watertown Plank Rd, Wauwatosa, WI, 53226, United States.

Group C Streptococcus (GCS) is part of the normal commensal flora of the upper airway, as well as frequently colonizes the skin, gastrointestinal tract, and female genital tract. It can also be implicated in mono- and polymicrobial infections of the skin and soft tissue, pharyngitis, bacteremia, endocarditis, septic arthritis, osteomyelitis, and meningitis. Our case study features a previously healthy 65-year-old male, who retired as a veterinarian one month prior, with Group C Streptococcus bacteremia complicated by septic polyarthritis, native mitral valve endocarditis, and lumbar discitis/osteomyelitis. Read More

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January 2021

Infected native aortic aneurysm with spondylodiscitis in an elderly septic man with back pain.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Tan Tock Seng Hospital, Singapore.

Infected aortic aneurysm is a rare disease and is often overlooked as a source of infection in septic elderly patients. We present a case of a septic elderly man with a ruptured infected aortic aneurysm caused by This condition was treated non-surgically with percutaneous endovascular aneurysm repair and antibiotics. The postoperative recovery was complicated a month later by spondylodiscitis and psoas abscess. Read More

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February 2021

Incidence of Sacral Osteomyelitis and Discitis After Minimally Invasive Sacrocolpopexy.

Female Pelvic Med Reconstr Surg 2021 Jan 29. Epub 2021 Jan 29.

From the Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh Medical Center Division of Urogynecology and Reconstructive Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences of the University of Pittsburgh Department of Obstetrics, Gynecology and Reproductive Sciences of the University of Pittsburgh, Magee-Womens Research Institute, Pittsburgh, PA.

Objective: The incidence and associated risk factors for sacral osteomyelitis and sacral discitis after sacrocolpopexy remain unknown. The aim of this study was to determine the incidence of sacral osteomyelitis and discitis after minimally invasive sacrocolpopexy and their association with the method of sacral mesh fixation.

Methods: This is a retrospective cohort study of consecutive minimally invasive sacrocolpopexies performed by 11 female pelvic medicine and reconstructive surgery board-certified surgeons from January 2009 to August 2019 within a single health system. Read More

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January 2021

Full endoscopic surgery for thoracic pathology: an assessment of supportive evidence.

EFORT Open Rev 2021 Jan 4;6(1):50-60. Epub 2021 Jan 4.

The Royal College of Surgeons of Edinburgh, Edinburgh, UK.

In the last five years, surgeons have applied endoscopic transforaminal surgical techniques mastered in the lumbar spine to the treatment of thoracic pathology.The aim of this systematic review was to collate the available literature to determine the place and efficacy of full endoscopic approaches used in the treatment of thoracic disc prolapse and stenosis.An electronic literature search of PubMed, Embase, the Cochrane database and Google Scholar was performed as suggested by the Preferred Reporting Items for Systematic Review and Meta-analysis statements. Read More

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January 2021

Rare case of osteomyelitis caused by and in a postmenopausal woman.

BMJ Case Rep 2021 Feb 1;14(2). Epub 2021 Feb 1.

Department of Biomedical Sciences, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, USA

Vertebral osteomyelitis is an infection of the vertebrae that can lead to spinal degeneration, most commonly caused by Here, we report an unusual case of pyogenic osteomyelitis caused by and in a 61-year-old postmenopausal woman. The patient presented with a 2-week history of worsening lower back pain and fever and a recent episode of cystitis following re-engagement of sexual activity. Imaging revealed a deterioration of vertebrae discs and spinal canal stenosis at the L3-L4 levels with a formation of abscess in the right psoas muscle. Read More

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February 2021

Rifampin-Associated Flu-Like Syndrome in a Patient Undergoing Treatment for a Device-Related Infection.

Cureus 2020 Dec 28;12(12):e12336. Epub 2020 Dec 28.

Internal Medicine, San Antonio Military Medical Center, San Antonio, USA.

Rifampin (or rifampicin) has found extensive use for the treatment of a variety of infectious illnesses, particularly tuberculosis and device-related infections. We describe the development of a flu-like syndrome in a patient undergoing extended antimicrobial therapy with rifampin for discitis and an associated device-related infection, which promptly resolved with discontinuation of rifampin. While the flu-like syndrome has been documented in prior literature covering the treatment of tuberculosis (where the dose regimen tends to be intermittent) there is less evidence for its occurrence in the treatment of device-related infections (which tend to be dosed daily). Read More

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December 2020

Minimally invasive debridement and drainage using intraoperative CT-Guide in multilevel spondylodiscitis: a long-term follow-up study.

BMC Musculoskelet Disord 2021 Jan 29;22(1):120. Epub 2021 Jan 29.

Department of Orthopaedics, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

Background: Spondylodiscitis is an unusual infectious disease, which usually originates as a pathogenic infection of intervertebral discs and then spreads to neighboring vertebral bodies. The objective of this study is to evaluate percutaneous debridement and drainage using intraoperative CT-Guide in multilevel spondylodiscitis.

Methods: From January 2002 to May 2017, 23 patients with multilevel spondylodiscitis were treated with minimally invasive debridement and drainage procedures in our department. Read More

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January 2021

A 64-Year-Old Man with Low Back Pain Due to Clostridium perfringens Lumbar Discitis.

Am J Case Rep 2021 Jan 22;22:e928014. Epub 2021 Jan 22.

Department of Medicine, Indiana University School of Medicine, South Bend, IN, USA.

BACKGROUND Lumbar discitis caused by Clostridium perfringens is extremely rare. There have only been 7 published cases of confirmed discitis caused by Clostridium perfringens. We write this report to underscore this unusual relationship by discussing an additional case and providing a review of the previously published cases so clinicians can adequately evaluate and treat patients presenting with discitis. Read More

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January 2021

Lumbar Disc Herniation and Preoperative Modic Changes: A Prospective Analysis of the Clinical Outcomes After Microdiscectomy.

Global Spine J 2021 Jan 19:2192568220976089. Epub 2021 Jan 19.

Department of Radiology, Ganga Hospital, Coimbatore, India.

Study Design: Prospective comparative cohort study.

Objectives: The study aims to elucidate the relationship between Modic endplate changes and clinical outcomes after a lumbar microdiscectomy.

Methods: Consecutive patients undergoing microdiscectomy for lumbar disc herniation (LDH) were prospectively studied. Read More

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January 2021

Total spine magnetic resonance imaging for detection of multifocal infection in pyogenic spondylodiscitis: a retrospective observational study.

BMC Musculoskelet Disord 2021 Jan 14;22(1):78. Epub 2021 Jan 14.

Department for Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Background: Due to the unspecific symptoms of spondylodiscitis (SpD), an early radiological examination is necessary. However, controversially discussed is the need for magnetic resonance imaging of the entire spine to exclude multisegmental infections and to determine the required surgical interventions. The aims of this study were to assess the incidence of multilevel non-contiguous pyogenic SpD and compare comorbidities, pain symptoms, and subsequent surgical strategies between unifocal (uSpD) and multifocal (mSpD) SpD. Read More

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January 2021

Characteristics, Management and Outcomes of Spondylodiscitis in Children: A Systematic Review.

Antibiotics (Basel) 2020 Dec 31;10(1). Epub 2020 Dec 31.

Paediatric Infectious Disease Unit, Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50139 Florence, Italy.

Spondylodiscitis (SD) is the concurrent infection of the intervertebral disc and the adjacent vertebral bodies. Currently, there is a substantial lack of structured reviews about this topic. The aim of this study was to systematically review the available literature in order to determine the main features of pediatric SD. Read More

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December 2020

Radiographic and clinical features of thoracic disk disease associated with myelopathy: a retrospective analysis of 257 cases.

Eur Spine J 2021 Jan 3. Epub 2021 Jan 3.

Department of Radiology, Peking University Third Hospital, 49 North Garden Road, Beijing, 100191, China.

Purpose: To analyze the clinical and radiographic characteristics of thoracic disk disease associated with myelopathy (TDM).

Methods: This is a retrospective clinical review of prospectively collected imaging data based at a single institute. Based on preoperative CT and MRI, we classified TDM as thoracic disk herniation (TDH), THD with ossification (THDO), TDH with posterior bony avulsions of the vertebrae (TDH with PBA), TDH with posterior vertebral osteophytes (TDH with PVO), giant thoracic osteophyte and calcific discitis with herniation (CDH). Read More

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January 2021

Video-assisted thoracoscopic image-guided spine surgery: evolution of 19 years of experience, from endoscopy to fully integrated 3D navigation.

Neurosurg Focus 2021 01;50(1):E8

Departments of1Neurological Surgery and.

Objective: The purpose of this study was to describe the evolution of thoracoscopic spine surgery from basic endoscopic procedures using fluoroscopy and anatomical localization through developmental iterations to the current technology use in which endoscopy and image-guided surgery are merged with intraoperative CT scanning.

Methods: The authors provided detailed explanations of their thoracoscopic spine surgery techniques, beginning with their early-generation endoscopy with fluoroscopic localization, which was followed with point surface matching techniques and early image guidance. The authors supplanted this with the modern era of image guidance, thoracoscopic spine surgery, and seamless integration that has reached its current level of refinement. Read More

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January 2021

Lumbosacral spondylodiscitis complicated by sepsis, osteomyelitis, epidural abscess formation and deep vein thrombosis.

BMJ Case Rep 2020 Dec 28;13(12). Epub 2020 Dec 28.

Rheumatology, Mater Dei Hospital, L-Imsida, Malta.

A 71-year-old man presented with a 3-month history of low back pain radiating to his right hip and thigh associated with lower limb weakness and constitutional symptoms. Imaging confirmed a lumbosacral spondylodiscitis at L2-3 and L5-S1 as well as a right-side psoas abscess which was treated with urgent CT-guided drainage and intravenous antibiotics. His admission was complicated by a number of issues, including the development of osteomyelitis with vertebral body destruction at multiple sites, epidural abscess formation and deep vein thrombosis. Read More

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December 2020

Limited Clinical Utility of Follow-up Blood Cultures in Patients With Streptococcal Bacteremia: An Opportunity for Blood Culture Stewardship.

Open Forum Infect Dis 2020 Dec 7;7(12):ofaa541. Epub 2020 Nov 7.

Pharmacy, Maine Medical Center, Portland, Maine, USA.

Background: The value of positive follow-up blood cultures (FUBCs) in streptococcal bacteremia has not been well defined. Therefore, we explored the frequency of and risk factors for positive FUBC in a retrospective cohort of patients with streptococcal bacteremia.

Methods: Adults ≥18 years of age, admitted with at least 1 positive blood culture for spp between 2013 and 2018 followed by at least 1 FUBC, were potentially eligible. Read More

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December 2020

Best Practices: CT-Guided Percutaneous Sampling of Vertebral Discitis-Osteomyelitis and Technical Factors Maximizing Biopsy Yield.

AJR Am J Roentgenol 2020 Dec 18. Epub 2020 Dec 18.

Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital.

Vertebral discitis-osteomyelitis is an infection of the intervertebral disc and vertebral bodies that may extend to adjacent paraspinal and epidural soft tissues. Its incidence is increasing, likely from improved treatments for predisposing chronic disease and increased rates of IV drug use and intravascular intervention. Because blood cultures are frequently negative in patients with vertebral discitis-osteomyelitis, biopsy is often indicated to identify a causative microorganism for targeted antimicrobial therapy. Read More

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December 2020

[Coexistent septic arthritis and spondylodiscitis as important differential diagnosis in immunosuppressed patients].

Z Rheumatol 2021 Mar 17;80(2):184-188. Epub 2020 Dec 17.

Medizinische Klinik III, Onkologie, Hämatologie, Rheumatologie und klinische Immunologie, Universitätsklinikum Bonn, Venusberg Campus 1, 53127, Bonn, Deutschland.

Septic arthritis and spondylodiscitis, especially in immunocompromised patients, constitute a major differential diagnosis of joint or back pain. This results in the invasion of a joint or spinal disc and its adjacent vertebral body by a pathogen. In most cases this is manifested as unspecific symptoms, such as local joint or back pain, fever and malaise. Read More

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Discitis following urinary tract infection manifesting as recurrent autonomic dysreflexia related to truncal movements in a person with tetraplegia.

BMJ Case Rep 2020 Dec 17;13(12). Epub 2020 Dec 17.

Spinal Injuries, Southport and Ormskirk Hospital NHS Trust, Southport, UK.

A 44-year-old male person with tetraplegia (C-5 AIS-A (American Spinal Cord Injury Association Standard Neurological Classification of Spinal Cord Injury Impairment Scale)) developed urinary tract infection and received appropriate antibiotic. Subsequently, he started sweating and shivering when he was sitting up; these symptoms resolved while lying on his back. Autonomic dysreflexia triggered by truncal movements continued to occur for 3 months. Read More

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December 2020

Obesity in spontaneous spondylodiscitis: a relevant risk factor for severe disease courses.

Sci Rep 2020 12 14;10(1):21919. Epub 2020 Dec 14.

Division of Spine Surgery, Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Spondylodiscitis is a serious and potentially life-threatening disease. Obesity is a risk factor for many infections, and its prevalence is increasing worldwide. Thus, the aim of this study was to describe characteristics of obese patients with spondylodiscitis and identify risk factors for a severe disease course in obese patients. Read More

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December 2020

Spinal pathologies and management strategies associated with cervical angina (pseudoangina): a systematic review.

J Neurosurg Spine 2020 Dec 4:1-8. Epub 2020 Dec 4.

1School of Medicine, University of California, Irvine, California.

Objective: Cervical angina, or pseudoangina pectoris, is a noncardiac syndrome of chest pain that often mimics angina pectoris but is a disease of the spine. Diagnosis of cervical angina can be difficult and is often overlooked, although once identified, it can be successfully managed through conservative therapies and/or a variety of surgical interventions. Ultimately, cervical angina is an important component of the list of differential diagnoses in noncardiac chest pain. Read More

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December 2020

Does image-guided biopsy of discitis-osteomyelitis provide meaningful information to impact clinical management?

Skeletal Radiol 2021 Jul 23;50(7):1325-1336. Epub 2020 Nov 23.

NYU Langone Health, Department of Radiology at Hospital for Joint Diseases, 301 East 17th Street, Rm 600, New York, NY, 10003, USA.

Objective: The aims of this study are to assess the diagnostic yield of image-guided biopsy for discitis-osteomyelitis (DO), identify factors associated with biopsy yield (laboratory, pre-defined MRI findings, and biopsy technique), and impact of biopsy on management of patients appropriately selected according to the Infectious Disease Society of America guidelines (IDSA).

Materials And Methods: This is a retrospective review of patients who underwent biopsy for suspected DO from 2011 to 2019. Reference standards to establish diagnosis of DO in order were histopathology/microbiology from biopsy or subsequent surgical sampling, positive blood culture or serology, and imaging/clinical follow-up. Read More

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Spontaneous Vertebral Aspergillosis, the State of Art: A Systematic Literature Review.

Neurospine 2021 Mar 17;18(1):23-33. Epub 2020 Nov 17.

UOC Chirurgia Vertebrale, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy.

Objective: Vertebral aspergillosis is quite rare conditions, often misdiagnosed, that requires long-term antibiotic therapy, and sometimes, surgical treatments. The present investigations were aimed to investigate the epidemiology, clinical-radiological aspects, treatment protocols, and outcomes of Aspergillus-mediated vertebral osteomyelitis.

Methods: A systematic review of the pertinent English literature according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines was performed. Read More

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Comparison of MRI, [F]FDG PET/CT, and Tc-UBI 29-41 scintigraphy for postoperative spondylodiscitis-a prospective multicenter study.

Eur J Nucl Med Mol Imaging 2021 06 18;48(6):1864-1875. Epub 2020 Nov 18.

Regional Centre of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Purpose: Postoperative infection still constitutes an important complication of spine surgery, and the optimal imaging modality for diagnosing postoperative spine infection has not yet been established. The aim of this prospective multicenter study was to assess the diagnostic performance of three imaging modalities in patients with suspected postoperative spine infection: MRI, [F]FDG PET/CT, and SPECT/CT with Tc-UBI 29-41.

Methods: Patients had to undergo at least 2 out of the 3 imaging modalities investigated. Read More

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Pyogenic psoas abscess on the dorsal side, and bacterial meningitis and spinal epidural abscess on the ventral side, both of which were induced by spontaneous discitis in a patient with diabetes mellitus: A case report.

J Diabetes Investig 2020 Nov 11. Epub 2020 Nov 11.

Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.

Type 2 diabetes mellitus patients are immunocompromised, particularly under poorly controlled conditions, and thereby they could develop rare inflammatory diseases, such as spontaneous discitis, pyogenic psoas abscess, spinal epidural abscess and bacterial meningitis. Herein we report a pyogenic psoas abscess on the dorsal side, and bacterial meningitis and spinal epidural abscess on the ventral side, both of which were induced by spontaneous discitis in a patient with poorly controlled type 2 diabetes mellitus. This case was very rare and interesting, because we successfully treated various infections with antibiotics over a long period of time, complicated by hyperglycemic crises, although the patient suffered severe bone destruction and required rehabilitation for a long time. Read More

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November 2020

Intoxication by hand sanitizer due to delirium after infectious spondylitis surgery during the COVID-19 pandemic: A case report and literature review.

Dong-Ju Lim

Int J Surg Case Rep 2020 27;77:76-79. Epub 2020 Oct 27.

Department of Orthopaedic Surgery, Seoul Spine Institute, Sanggye Paik Hospital, College of Medicine, Inje University, Department of Orthopaedic Surgery, Dongil-ro 1342, Nowon-gu, Seoul, 139-707, South Korea. Electronic address:

Introduction: Alcohol-containing hand sanitizers are part of the strategy to prevent person-to-person transmission during the COVID-19 pandemic. The purpose of this report was to present a case of ethanol-induced hand sanitizer intoxication after spine surgery in a patient with a postoperative delirious state.

Presentation Of Case: A 63-year-old man was admitted to the spine department with intractable back pain as the main symptom and diagnosed with infectious spondylitis with discitis. Read More

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October 2020

Defining Disc Biopsy Timing in Relation to Blood Culture Results for Inpatients with Suspected Discitis-Osteomyelitis.

J Vasc Interv Radiol 2021 01 31;32(1):121-127. Epub 2020 Oct 31.

Department of Radiology and Imaging Sciences, University of Utah Health Sciences Center, 30 North, 1900 East #1A071, Salt Lake City, UT 84132-2140.

Purpose: To determine optimal timing of biopsy for suspected discitis-osteomyelitis (DOM) with respect to preliminary blood culture results and the effect of biopsy timing on hospital length of stay (LOS).

Materials And Methods: This retrospective study reviewed disc/vertebral biopsies for suspected DOM performed between 2010 and 2018. A total of 107 disc/vertebral biopsies were performed on 96 inpatients (mean ± SD age 57. Read More

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January 2021

The impact of antibiotic pre-treatment on diagnostic yield of CT-guided biopsy for spondylodiscitis: A multi-centre retrospective study and meta-analysis.

J Med Imaging Radiat Oncol 2021 Apr 28;65(2):146-151. Epub 2020 Oct 28.

Radiology Department, Auckland Hospital, Auckland District Health Board, Auckland, New Zealand.

Introduction: Patients with suspected spondylodiscitis often undergo CT-guided biopsy to identify a causative microbiological organism. Antibiotic pre-treatment has been postulated as a cause for a negative biopsy, although previous clinical studies have been heterogenous with a meta-analysis suggesting no effect. The aim of this study was to assess the impact of antibiotic pre-treatment on microbiological yield. Read More

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