2,545 results match your criteria Diskitis


Infectious Spondylitis Mimics: Mechanisms of Disease and Imaging Findings.

Authors:
Humberto Morales

Semin Ultrasound CT MR 2018 Dec 15;39(6):587-604. Epub 2018 Nov 15.

Section of Neuroradiology, University of Cincinnati Medical Center, Cincinnati, OH. Electronic address:

Infectious processes of the spine are on the rise; in this scenario recognition of entities imitating infection is very important. The discovertebral unit is regarded as one of the most important and active sites in the spine. Importantly, the vertebral bony rim and the anterior corners of the vertebral bodies have significant vascularization, they are the last regions to ossify in the developmental process and suffer mechanical forces. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08872171183011
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http://dx.doi.org/10.1053/j.sult.2018.11.006DOI Listing
December 2018
1 Read

Spondylodiscitis developing in a young man - diagnostic and therapeutic difficulties.

Reumatologia 2018 31;56(5):328-332. Epub 2018 Oct 31.

Clinic of Rheumatology, UMHAT St. Ivan Rilski University Hospital, Sofia, Bulgaria.

Infectious spondylodiscitis is characterized by vertebral osteomyelitis, spondylitis, and discitis. Patients present with persistent low back pain, fever, or neurological findings. Diagnosis is made with a combination of clinical, radiological, and laboratory findings. Read More

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http://dx.doi.org/10.5114/reum.2018.79505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263306PMC
October 2018
1 Read

Long-Term Follow-Up of a Patient with Spondylodiscitis after Laparoscopic Sacrocolpopexy: An Unusual Complication with a Review of the Literature.

Urol Int 2018 Nov 28:1-5. Epub 2018 Nov 28.

Department of Obstetrics and Gynecology, Division of Urogynecology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.

Sacrocolpopexy is the gold standard treatment for apical compartment prolapse with reported success rates of 78-100%. Spondylodiscitis is a rare complication of sacrocolpopexy and includes a spectrum of spinal infections such as discitis, osteomyelitis, epidural abscess, meningitis, subdural empyema, and spinal cord abscess. Here we report a case of spondylodiscitis following laparoscopic sacrocolpopexy with long-term follow-up and discuss management of spondylodiscitis after abdominal sacrocolpopexy, with a review of the literature. Read More

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http://dx.doi.org/10.1159/000494370DOI Listing
November 2018
1 Read

Microendoscopic discectomy for lumbar disc herniations.

J Craniovertebr Junction Spine 2018 Jul-Sep;9(3):156-162

Department of Neurosurgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.

Introduction: Lumbar disc herniation is one of the main causes of discogenic low back pain and reported to affect 60%-80% of people during their lifetime. The two main surgical modalities for intervertebral disc surgery are standard open discectomy and minimally invasive discectomy which include percutaneous endoscopic lumbar discectomy and microendoscopic discectomy (MED). We report our experience with the same technique of MED to evaluate the efficacy of MED for lumbar disc pathology. Read More

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http://www.jcvjs.com/text.asp?2018/9/3/156/242817
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http://dx.doi.org/10.4103/jcvjs.JCVJS_61_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187901PMC
November 2018
5 Reads

Spinal involvement with calcium pyrophosphate deposition disease in an academic rheumatology center: A series of 37 patients.

Semin Arthritis Rheum 2018 Oct 14. Epub 2018 Oct 14.

Université Paris Diderot France, France; Department of Rheumatology, Hôpital Lariboisière, Assistance Publique des Hôpitaux de Paris, 75010 Paris, France; INSERM U1132, Hôpital Lariboisière, Université Paris Diderot, France. Electronic address:

Background: Calcium pyrophosphate dihydrate deposition disease (CPPD) has been reported to involve the spine, but few systematic studies have been published.

Objective: To further characterize the spinal involvement with CPPD by a review of CPPD patients hospitalized in a rheumatology department.

Methods: We retrospectively reviewed data for patients consecutively admitted with a diagnosis of CPPD in the rheumatology department of Lariboisière hospital in Paris, France over 5 years by using a standardized protocol and electronic case report forms. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183043
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http://dx.doi.org/10.1016/j.semarthrit.2018.10.009DOI Listing
October 2018
5 Reads

Extreme lateral interbody fusion (XLIF) as a treatment for acute spondylodiscitis: Leeds spinal unit experience.

J Clin Neurosci 2018 Nov 5. Epub 2018 Nov 5.

Department of Neurosurgery, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address:

Extreme lateral interbody fusion (XLIF) is a minimally invasive lateral trans-psoas approach to the thoraco-lumbar spine that enables surgical debridement of the disc space and facilitates fusion. Previous reports are limited to case series, which have no outcomes measuring improvement. We aim to determine the effectiveness of XLIF in the treatment of patients with spondylodiscitis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183021
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http://dx.doi.org/10.1016/j.jocn.2018.10.063DOI Listing
November 2018
3 Reads

Vertebral Osteomyelitis, Discitis, and Epidural Abscess: A Rare Complication of Endocarditis.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618807504. Epub 2018 Oct 28.

State University of New York Upstate Medical University, Syracuse, NY, USA.

In this article, we report the case of a 75-year-old man who was presented with new low back pain for 2 weeks. His past history was significant for severe aortic stenosis necessitating bioprosthetic aortic valve placement 4 years ago, hypertension, and coronary artery disease. His physical examination was positive for point tenderness over the lower lumbar spine. Read More

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http://dx.doi.org/10.1177/2324709618807504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207954PMC
October 2018
8 Reads

Pattern-Based Interpretation Criteria for F-Fludeoxyglucose Positron Emission Tomography/Computed Tomography in the Assessment of Pyogenic Spine Infection.

Can Assoc Radiol J 2018 Nov;69(4):397-408

Departments of Medicine, and Microbiology, Immunology and Infectious Diseases, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S08465371183011
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http://dx.doi.org/10.1016/j.carj.2018.06.004DOI Listing
November 2018
4 Reads

Infected abdominal aortic aneurysm graft complicated by lumbar discitis.

BJR Case Rep 2018 9;4(2):20170101. Epub 2018 Feb 9.

Department of Radiology, Poole Hospital NHS Foundation Trust, Poole, UK.

We present the case of a 68-year-old male, who underwent open abdominal aortic graft in August 2016 owing to a ruptured large infrarenal abdominal aneurysm. He subsequently presented 6 months later with back pain, general weakness, reduced mobility and cachexia. He underwent CT, MRI and fluorodeoxyglucose (PDG)-PET spinal imaging, all modalities showing signs of aortic graft infection complicated by L4/5 discitis. Read More

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http://www.birpublications.org/doi/10.1259/bjrcr.20170101
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http://dx.doi.org/10.1259/bjrcr.20170101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159111PMC
February 2018
5 Reads

Diagnostic Quandary: Agbeni Vertebral Osteomyelitis and Epidural Abscess.

Case Rep Orthop 2018 20;2018:1091932. Epub 2018 Sep 20.

Rockford Pain Center, Rockford, USA.

Salmonella vertebral discitis/osteomyelitis is a rare manifestation of Salmonella infection. Here, we report a case of a 54-year-old Caucasian male who presented with five weeks of progressively worsening bilateral low back, buttock, and lower extremity pain following an 8-foot fall onto concrete from a ladder. Initial workup following the fall included hip X-ray and MRI of the lumbar spine and revealed only mild lumbar facet arthropathy and moderate left neural foraminal stenosis at L3-L4 without any concomitant hip or spine fracture. Read More

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https://www.hindawi.com/journals/crior/2018/1091932/
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http://dx.doi.org/10.1155/2018/1091932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171215PMC
September 2018
7 Reads

Claw sign: MRI of degenerative disc disease.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:125

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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http://doi.wiley.com/10.1111/1754-9485.06_12786
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http://dx.doi.org/10.1111/1754-9485.06_12786DOI Listing
October 2018
3 Reads

Transforaminal Interbody Debridement and Fusion to Manage Postdiscectomy Discitis in Lumbar Spine.

World Neurosurg 2019 Jan 9;121:e755-e760. Epub 2018 Oct 9.

Department of Orthopaedic Surgery, Spine Section, Bone and Joint Research Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Traditionally, nonoperative management with long-term antibiotics and bed rest has been recommended as first-line treatment for most patients with postoperative discitis. A recent trend in treatment under a limited range of indications has been to perform surgical débridement followed by long-term administration of antibiotics. This descriptive study investigated whether transforaminal lumbar interbody débridement and fusion (TLIDF) combined with intravenous antibiotics is appropriate to manage postdiscectomy discitis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183226
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http://dx.doi.org/10.1016/j.wneu.2018.09.211DOI Listing
January 2019
4 Reads

Worldwide research productivity in the field of back pain: A bibliometric analysis.

Authors:
Bin Wang Peng Zhao

Medicine (Baltimore) 2018 Oct;97(40):e11566

Department of Cardiovascular, The First Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.

Background: This study aimed to show the world research productivity in the field of back pain and to help researchers follow the scientific development and promote the cooperation in this field.

Methods: Web of Science (WoS) database was searched from 1995 to 2016 without other restrictions. The keywords were as follows: "lumbar NEAR pain," "back pain," "dorsalgia," "backache," "lumbago," "back NEAR disorder," and "discitis. Read More

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http://dx.doi.org/10.1097/MD.0000000000011566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200510PMC
October 2018
11 Reads

Spinal Coccidioidomycosis: MR Imaging Findings in 41 Patients.

AJNR Am J Neuroradiol 2018 Nov 4;39(11):2148-2153. Epub 2018 Oct 4.

Department of Radiology (J.R.), Mayo Clinic College of Medicine, Phoenix, Arizona.

Background And Purpose: is a dimorphic fungus endemic to the Southwest United States and Mexico, and at our institution, it is a relatively common pathogen presenting with a broad spectrum of associated spine diseases. We describe the various spinal manifestations resulting from coccidioidal infection and provide MR imaging examples from 41 pathologically proved cases.

Materials And Methods: Retrospective electronic medical record and PACS searches were performed. Read More

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http://www.ajnr.org/lookup/doi/10.3174/ajnr.A5818
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http://dx.doi.org/10.3174/ajnr.A5818DOI Listing
November 2018
3 Reads

Management of Postoperative Discitis: A Review of 31 Patients.

Asian J Neurosurg 2018 Jul-Sep;13(3):703-706

Department of Anesthesiology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Background: The aim of the study was to retrospectively evaluate the outcome of medical management of postoperative discitis (POD).

Materials And Methods: A total of 31 patients treated for POD were included in the study. Clinical, radiological, and laboratory data of all patients were collected and evaluated. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_233_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159077PMC
October 2018
1 Read

Evaluation and Management of Pyogenic and Tubercular Spine Infections.

Curr Rev Musculoskelet Med 2018 Dec;11(4):643-652

The Rothman Institute, 925 Chestnut St, 5th Floor, Philadelphia, PA, 19107, USA.

Purpose Of Review: To review the most current diagnostic tools and treatment options for pyogenic and tubercular spine infection.

Recent Findings: Recent studies have focused on risk factors for failed nonoperative management in order to improve patient selection. Also, spine instrumentation and different grafting options have been safely utilized in the setting of an active infection without increasing the incidence of reoccurrence. Read More

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http://dx.doi.org/10.1007/s12178-018-9523-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220010PMC
December 2018
1 Read

Appropriate duration of post-surgical intravenous antibiotic therapy for pyogenic spondylodiscitis.

BMC Infect Dis 2018 Sep 17;18(1):468. Epub 2018 Sep 17.

Department of Orthopaedic Surgery, Chang Gung Memorial Hospital in Keelung, Chang Gung University, 7F, No.222, Maijin Road, Keelung, 20401, Taiwan.

Background: Most guidelines recommend 6 to 12 weeks of parenteral antibiotic treatment for pyogenic spondylodiscitis. When surgical debridement is adequately performed, further intravenous antibiotic treatment duration can be reduced than that of conservative treatment alone theoretically. However, the appropriate duration of post-surgical parenteral antibiotic treatment is still unknown. Read More

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http://dx.doi.org/10.1186/s12879-018-3377-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142394PMC
September 2018
1 Read

Thoracic Discitis in Ankylosing Spondylitis.

Cureus 2018 Jul 12;10(7):e2972. Epub 2018 Jul 12.

Rheumatology, University of Kansas School of Medicine - Wichita, Wichita, USA.

Chronic ankylosing spondylitis can lead to several rare long-term complications including cauda equina syndrome and inflammatory discitis especially without treatment. These complications are uncommon, but there is evidence that they can be treated with anti-tumor necrosis factor (TNF) inhibitors. We present a case of a 52-year-old male with a 30-year history of undiagnosed ankylosing spondylitis with cauda equina syndrome on initial outpatient presentation with a negative lumbosacral magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.7759/cureus.2972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136886PMC
July 2018
1 Read

An Uncommon Case of Pyogenic Spondylodiscitis Caused by .

Case Rep Orthop 2018 14;2018:3127613. Epub 2018 Aug 14.

Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

An 81-year-old man presented with severe back pain. Magnetic resonance imaging detected L5/S discitis without signs of epidural abscess. Punctures of the disc revealed that the causative organism was , which is part of the normal flora of the oral cavity and an uncommon causative pathogen of spondylodiscitis. Read More

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http://dx.doi.org/10.1155/2018/3127613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112214PMC
August 2018
1 Read

A prospective study of screening for musculoskeletal pathology in the child with a limp or pseudoparalysis using erythrocyte sedimentation rate, C-reactive protein and MRI.

J Child Orthop 2018 Aug;12(4):398-405

Department of Orthopaedic Surgery, Peterborough City Hospital, Bretton Gate, Peterborough, UK.

Purpose: To determine if the detection of musculoskeletal pathology in children with a limp or acute limb disuse can be optimized by screening with blood tests for raised inflammatory markers, followed by MRI.

Methods: This was a prospective observational study. Entry criteria were children (0 to 16 years of age) presenting to our emergency department with a non-traumatic limp or pseudoparalysis of a limb, and no abnormality on plain radiographs. Read More

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http://dx.doi.org/10.1302/1863-2548.12.180004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090194PMC
August 2018
1 Read

Degenerative Disc Disease Mimicking Spondylodiscitis with Bilateral Psoas Abscesses.

World Neurosurg 2018 Dec 24;120:43-46. Epub 2018 Aug 24.

Neuroradiology, Service of Diagnostic and Interventional Radiology, Hôpital de Sion, Centre Hospitalier Universitaire Vaudois, Sion, Switzerland.

Background: Sequestered disc fragments may present as a lesion with peripheral enhancement on magnetic resonance imaging. When located in the psoas muscle compartment, this finding could mimic an abscess.

Case Description: We describe a case of a 52-year-old man who returned from Togo after 2 years of living in precarious conditions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183189
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http://dx.doi.org/10.1016/j.wneu.2018.08.116DOI Listing
December 2018
12 Reads

Recent Increase in the Rate of Spinal Infections May be Related to Growing Substance-Use Disorder in the State of Washington: Wide Population-based Analysis of the Comprehensive Hospital Abstract Reporting System (CHARS) Database.

Spine (Phila Pa 1976) 2018 Jul 27. Epub 2018 Jul 27.

Swedish Neuroscience Institute, Seattle, WA.

Study Design: Epidemiological study.

Objective: To evaluate trends in the incidence of spinal infections and the possible role of substance use disorder as a key associated factor.

Summary Of Background Data: Spinal infections (SI) pose major diagnostic and therapeutic challenge in developed countries, resulting in substantial morbidity and mortality. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002819DOI Listing

Fungal Lumbosacral Osteomyelitis After Robotic-Assisted Laparoscopic Sacrocolpopexy.

Female Pelvic Med Reconstr Surg 2018 Nov/Dec;24(6):e46-e48

From the Department of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA.

Sacral osteomyelitis is a rare complication after robotic sacrocolpopexy, with previous reports of enteric and skin flora as inciting organisms. We report a patient who presented with severe low back pain and fever 6 weeks after a robotic sacrocolpopexy, who was subsequently diagnosed as having lumbosacral discitis and osteomyelitis with thoracic intervertebral extension. Empiric antibiotic therapy was initially administered. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000612DOI Listing
July 2018
1 Read

[A woman with spontaneous neck pain].

Ned Tijdschr Geneeskd 2018 May 22;161. Epub 2018 May 22.

Medisch Spectrum Twente, afd. Neurologie, Enschede.

A 42-year-old woman presented with neck pain without previous trauma. On suspicion of spondylodiscitis, an MRI of the cervical spine was made. This MRI and an additional CT showed calcific tendinitis of the longus colli muscle, a self-limiting disorder. Read More

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Spondylodiscitis caused by Bordetella holmesii, a misrecognized pathogen emerging in invasive infections.

Int J Infect Dis 2018 Oct 19;75:95-97. Epub 2018 Jul 19.

Service de Bactériologie-Hygiène, Centre de Biologie Pathologie, CHRU de Lille, Lille 59037, France. Electronic address:

We report a case of spondylodiscitis caused by Bordetella holmesii, an emergent pathogen. This small Gram-negative rod was first known as a cause of invasive infections on asplenic patients. This case describes a spondylodiscitis due to this bacterium in an immunocompetent patient. Read More

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http://dx.doi.org/10.1016/j.ijid.2018.07.014DOI Listing
October 2018

spondylodiscitis in a patient with HIV infection and restored CD4 count.

BMJ Case Rep 2018 Jul 15;2018. Epub 2018 Jul 15.

Department of Infectious Diseases and Immunity, Jessa Ziekenhuis vwz, Hasselt, Belgium.

() is a rare condition and mostly seen in elderly or immunocompromised patients. We present the first case of spondylodiscitis in a virologically suppressed HIV seropositive patient with low back pain. MRI was performed and showed spondylodiscitis of the L4-L5 region. Read More

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http://dx.doi.org/10.1136/bcr-2018-225272DOI Listing
July 2018
3 Reads

High mortality from pyogenic vertebral osteomyelitis: a retrospective cohort study.

Spinal Cord Ser Cases 2018 5;4:59. Epub 2018 Jul 5.

Department of Internal Medicine, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.

Study Design: Retrospective cohort study.

Objective: In this pilot study, we aimed to assess the incidence, diagnostic strategies, treatment regimens, and outcomes of pyogenic vertebral osteomyelitis (PVO), in a non-urban, Northern European population during 1 year.

Setting: Region Zealand, Denmark. Read More

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http://dx.doi.org/10.1038/s41394-018-0099-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033860PMC
July 2018
2 Reads

Small bowel perforation by toothpick.

BMJ Case Rep 2018 Jul 11;2018. Epub 2018 Jul 11.

Orthopaedics and Traumatology, North District Hospital, Hong Kong, Hong Kong.

Toothpick ingestion is a rare but potentially fatal condition which may cause bowel perforation and rare complications if it migrates out of the gastrointestinal tract. This case report describes a delayed presentation of toothpick-induced small bowel injury leading to abdominal wall abscess and spondylodiscitis. A 51-year-old man was admitted twice with fever and loin pain, but repeated non-contrast CT was reported to be unremarkable. Read More

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http://dx.doi.org/10.1136/bcr-2018-225258DOI Listing
July 2018
4 Reads

Effectiveness of Bi-Needle Technique (Hybrid Yeung Endoscopic Spine System/Transforaminal Endoscopic Spine System) for Percutaneous Endoscopic Lumbar Discectomy.

World Neurosurg 2018 Nov 6;119:e53-e59. Epub 2018 Jul 6.

Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, China.

Objective: The bi-needle technique is a new technique for percutaneous endoscopic lumbar discectomy. This technique combines the advantages of Yeung endoscopic spine system (YESS) and transforaminal endoscopic spine system (TESSYS) techniques. The aim of this study was to evaluate effectiveness of the bi-needle technique for percutaneous endoscopic lumbar discectomy and compare it with the TESSYS technique. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.220DOI Listing
November 2018
4 Reads

Pediatric spinal infections-a review of non-tuberculous infections.

Childs Nerv Syst 2018 Oct 3;34(10):1947-1956. Epub 2018 Jul 3.

Bombay Hospital Institute of Medical Sciences, Mumbai, India.

Pediatric spinal infection includes spinal epidural abscess, spondylodiscitis and intradural (extramedullary and intramedullary) spinal infections. However, these entities are extremely rare and no clear guidelines exist for their management. Pertinent literature was searched and a detailed narrative review of this topic is presented. Read More

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http://dx.doi.org/10.1007/s00381-018-3885-8DOI Listing
October 2018
7 Reads

Discitis in Adults.

JBJS Rev 2018 Jun;6(6):e6

WESTMED Spine Center, Yonkers, New York.

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http://dx.doi.org/10.2106/JBJS.RVW.17.00104DOI Listing
June 2018
1 Read

Ceftazidime/Avibactam for Refractory Bacteremia, Vertebral Diskitis/Osteomyelitis with Pre-Vertebral Abscess and Bilateral Psoas Pyomyositis Secondary to Klebsiella Pneumoniae Carbapenemase-Producing Bacteria (KPC).

P R Health Sci J 2018 Jun;37(2):128-131

Division of Infectious Diseases, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR; Department of Microbiology and Medical Zoology, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

A 36-year-old man was admitted to the intensive care unit due to diabetic ketoacidosis and pneumonia requiring mechanical ventilation. Three weeks after admission, he developed a refractory bacteremia with Klebsiella pneumoniae carbapenemase-producing bacteria (KPC). He remained febrile and with bacteremia for six weeks despite therapy with polymyxin B, carbapenems, and amikacin. Read More

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June 2018
11 Reads

Staphylococcus-Associated Glomerulonephritis Mimicking Henoch-Schönlein Purpura and Cryoglobulinemic Vasculitis in a Patient With an Epidural Abscess: A Case Report and Brief Review of the Literature.

Can J Kidney Health Dis 2018 31;5:2054358118776325. Epub 2018 May 31.

Division of Nephrology, Institute of Health Policy, Management and Evaluation, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Rationale: Staphylococcus-associated glomerulonephritis (SAGN) is a rare immune complex-mediated glomerulonephritis associated with active infection. We report a case illustrating the importance of clinical history and kidney biopsy findings in establishing the correct diagnosis.

Presenting Concerns Of The Patient: We report the case of a 64-year-old man with alcohol-associated cirrhosis, type 2 diabetes mellitus, and hypertension who presented to hospital with lower back and abdominal pain, rectal bleeding, a purpuric lower extremity rash, and oliguric acute kidney injury with microscopic hematuria and nephrotic-range proteinuria. Read More

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http://dx.doi.org/10.1177/2054358118776325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985547PMC
May 2018
7 Reads

Successful Conservative Management of Delayed Cervical Spondylodiscitis with Epidural Abscess Caused by Esophageal Diverticulitis: A Case Report and Review of Literature.

World Neurosurg 2018 Oct 5;118:250-260. Epub 2018 Jun 5.

Department of Orthopedic Surgery, Navy General Hospital, Beijing, China. Electronic address:

Background: Cervical spondylodiscitis with spinal epidural abscess (SEA) is not a rare medical condition and usually requires urgent decompression of neural structures and stabilization of the spine followed by antibiotic therapy for the prevention of severe neurologic deficits.

Case Description: In this report, we present a 43-year-old male patient with the chief complaint of neck pain and intermittent fever accompanying by slight dysphagia. After 2 weeks, he felt mild and transient numbness on the left upper limb. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.207DOI Listing
October 2018
3 Reads

An aggressive form of infective endocarditis presenting with limb weakness.

BMJ Case Rep 2018 Jun 4;2018. Epub 2018 Jun 4.

Department of Cardiology, Royal Free London NHS Foundation Trust, London, UK.

We present the case of a 49-year-old man with a bicuspid aortic valve who presented to the emergency department with limb weakness and a fever. Blood tests revealed a fulminant septic process with bacteraemia, anaemia and thrombocytopenia. Imaging revealed a cervical spinal abscess and discitis causing spinal cord compression, in addition to multiple cerebral septic emboli, pleural effusions and ascites. Read More

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http://dx.doi.org/10.1136/bcr-2017-223775DOI Listing
June 2018
4 Reads

One-stage posterior debridement and fusion combined with irrigation and drainage for the treatment of postoperative lumbar spondylodiscitis.

Acta Orthop Traumatol Turc 2018 Jul 18;52(4):277-282. Epub 2018 May 18.

Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, PR China; Research Center of Sports Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, PR China. Electronic address:

Objective: The aim of this study was to evaluate the clinical outcomes of one-stage posterior debridement, interbody fusion, and instrumentation, combined with irrigation and drainage, for treating lumbar spondylodiscitis.

Methods: The study included 23 patients (13 male and 10 female, mean age: 45 years) who had posterior debridement, interbody fusion, and instrumentation, followed by continuous closed irrigation and drainage for lumbar postoperative spondylodiscitis. The visual analog scale, Oswestry disability index, and lumbar lordosis angle were assessed before and after surgery to evaluate the clinical outcome. Read More

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http://dx.doi.org/10.1016/j.aott.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150443PMC
July 2018
2 Reads

Diagnostic yield of repeat CT-guided biopsy for suspected infectious spondylodiscitis.

Skeletal Radiol 2018 Oct 18;47(10):1403-1410. Epub 2018 May 18.

Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Objective: The purpose of this study was to examine the yield of repeat CT-guided biopsy in patients with suspected infectious spondylodiscitis following an initial biopsy with negative microbiology, and to identify factors associated with successful pathogen isolation.

Materials And Methods: In this retrospective study, 21 patients (12 men, 9 women; mean age, 52, range, 12-84) were identified with clinically and radiologically suspected infectious spondylodiscitis who underwent repeat biopsy following negative cultures from an initial biopsy. The microbe yield as well as demographic, clinical, and laboratory findings were reviewed and statistical analysis was performed. Read More

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http://link.springer.com/10.1007/s00256-018-2972-y
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http://dx.doi.org/10.1007/s00256-018-2972-yDOI Listing
October 2018
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Letter to the editor on "A rare case of Candida glabrata spondylodiscitis: Case report and literature review" by Gagliano et al.

Int J Infect Dis 2018 07 14;72:19. Epub 2018 May 14.

Department of Neurosurgery, Zuyderland Medical Center Heerlen, and Department of Neurosurgery, Maastricht University Medical Center, The Netherlands.

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http://dx.doi.org/10.1016/j.ijid.2018.05.005DOI Listing
July 2018
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Re: Decompression alone versus fusion for pyogenic spondylodiscitis. Spine Journal 17: 1120-1126.

Spine J 2018 05;18(5):912

School of Medicine, China Medical University, No. 91, Hsueh-Shuh Rd, Taichung 40402, Taiwan; Department of Orthopedic Surgery, China Medical University Hospital, No. 2, Yuh-Der Rd, Taichung 40402, Taiwan.

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http://dx.doi.org/10.1016/j.spinee.2018.01.020DOI Listing
May 2018
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Salmonella potsdam causing lumbar vertebral osteomyelitis: A case report.

Medicine (Baltimore) 2018 May;97(18):e0682

Orthopaedic Center of People's Liberation Army, the Affiliated Southeast Hospital of Xiamen University, Zhangzhou, Fujian Province, P. R. China.

Rationale: Salmonella osteomyelitis is an uncommon complication of salmonella infection, especially the salmonella vertebral osteomyelitis (SVO).

Patient Concerns: We reported a case of a 29-year-old female who presented with serious lower back pain and severe limitation of motion for 50 days with no obvious inducements. She once had a fever up to 39. Read More

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http://dx.doi.org/10.1097/MD.0000000000010682DOI Listing
May 2018
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Diskitis as Manifestation of Gait Disturbance.

Iran J Child Neurol 2018 ;12(2):117-120

Pediatrics Growth Disorders Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Gait disturbance is a common presentation of neurologic disease in children. Limping is a kind of gait dysfunction that occurs due to neurologic & skeletal diseases. Diskitis is an inflammatory process noted as one of the significant causes of limping especially in children aged less than 3 yr. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904747PMC
January 2018
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A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report.

J Infect Chemother 2018 Oct 22;24(10):849-851. Epub 2018 Apr 22.

Center for Infectious Diseases and Infection Control, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.

Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral osteomyelitis cases caused by this organism have rarely been reported. Ampicillin or amoxicillin has been used in the previously reported discitis cases; however, no cases have been reported that is treated with levofloxacin. We report the first published case we chose levofloxacin to treat. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.03.013DOI Listing
October 2018
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Spinal infections in children.

Bone Joint J 2018 04;100-B(4):542-548

Division of Paediatric Orthopaedics, University Hospitals of Geneva, 6 Rue Willy Donzé, 1211 Geneva 14, Switzerland.

Aims: This multicentre, retrospective study aimed to improve our knowledge of primary pyogenic spinal infections in children by analyzing a large consecutive case series.

Patients And Methods: The medical records of children with such an infection, treated at four tertiary institutions between 2004 and 2014, were analyzed retrospectively. Epidemiological, clinical, paraclinical, radiological, and microbiological data were evaluated. Read More

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http://online.boneandjoint.org.uk/doi/10.1302/0301-620X.100B
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http://dx.doi.org/10.1302/0301-620X.100B4.BJJ-2017-1080.R1DOI Listing
April 2018
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Clinical and Radiographic Results of a Minimally Invasive Lateral Transpsoas Approach for Treatment of Septic Spondylodiscitis of the Thoracolumbar and Lumbar Spine.

World Neurosurg 2018 Aug 4;116:e48-e56. Epub 2018 Apr 4.

Department of Spine Surgery, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address:

Background: The minimally invasive lateral transpsoas approach allows retroperitoneal access for discectomy and graft placement. However, the procedure has rarely been used for the treatment of septic spondylodiscitis. The purposes of this study were to evaluate the clinical and radiographic outcomes from this minimally invasive procedure for septic spondylodiscitis. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.03.193DOI Listing
August 2018
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Bone and joint infection.

Clin Med (Lond) 2018 Mar;18(2):150-154

Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Bone and joint infections include septic arthritis, prosthetic joint infections, osteomyelitis, spinal infections (discitis, vertebral osteomyelitis and epidural abscess) and diabetic foot osteomyelitis. All of these may present through the acute medical take. This article discusses the pathogenesis of infection and highlights the importance of taking a careful history and fully examining the patient. Read More

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http://dx.doi.org/10.7861/clinmedicine.18-2-150DOI Listing
March 2018
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Spondylodiscitis in a 54-year-old female scuba diver.

BMJ Case Rep 2018 Mar 28;2018. Epub 2018 Mar 28.

School of Allied Health Sciences, Griffith University - Gold Coast Campus, Southport, Queensland, Australia.

A 54-year-old woman presented to a Sports Physician with a 4-year history of haemochromatosis, and she had a medical history that included a congenital spondylolisthesis resulting in a fusion of L4-S1 at age 16 years, episodic mechanical low back pain and an absence of other significant musculoskeletal symptoms. On presentation, she reported 18 months of severe low back pain that started after a scuba diving trip. After the onset of this low back pain, she developed gastrointestinal symptoms from The gastrointestinal symptoms improved with a course of antibiotics, but the back pain persisted in spite of analgesics, non-steroidal anti-inflammatories and several attempts at different conservative management. Read More

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http://dx.doi.org/10.1136/bcr-2017-222274DOI Listing
March 2018
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Clinical Utility of Diffusion-Weighted Imaging in Spinal Infections.

Clin Neuroradiol 2018 Mar 26. Epub 2018 Mar 26.

Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Rm. L-358, 94143-0628, San Francisco, CA, USA.

Purpose: Both laboratory markers and radiographic findings in the setting of spinal infections can be nonspecific in determining the presence or absence of active infection, and can lag behind both clinical symptoms and antibiotic response. Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) has been shown to be helpful in evaluating brain abscesses but has not been commonly used in evaluating spinal infections. We aimed to correlate findings on DWI of the spine to results of microbiological sampling in patients with suspected spinal infections. Read More

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http://dx.doi.org/10.1007/s00062-018-0681-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158113PMC
March 2018
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Recurrent discitis in the acute rehab setting: a case report.

Spinal Cord Ser Cases 2018 21;4:23. Epub 2018 Mar 21.

1Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, USA.

Introduction: Discitis is an infection of the intervertebral disc space that can lead to paralysis, sepsis, epidural abscess, or other life-threatening complications if left untreated and may sometimes present with limited laboratory abnormalities to clue a diagnosis.

Case Presentation: We present a case of a 67-year-old female in an acute rehabilitation setting who had presenting symptoms of sudden unexplained back pain refractory to pain control. She had a previous history of discitis and multiple failed knee replacement surgeries secondary to MSSA infections. Read More

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http://dx.doi.org/10.1038/s41394-018-0052-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862829PMC
March 2018
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Epidemiology, Microbiological Diagnosis, and Clinical Outcomes in Pyogenic Vertebral Osteomyelitis: A 10-year Retrospective Cohort Study.

Open Forum Infect Dis 2018 Mar 10;5(3):ofy037. Epub 2018 Mar 10.

Division of Medicine, John Hunter Hospital, New Lambton Heights, NSW, Australia.

Background: Pyogenic vertebral osteomyelitis (PVO) is rising in incidence, but optimal methods of investigation and duration of antibiotic therapy remain controversial.

Methods: We conducted a single-center retrospective cohort study of PVO at an Australian teaching hospital. We included all adults with a first episode of PVO between 2006 and 2015. Read More

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http://dx.doi.org/10.1093/ofid/ofy037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846292PMC
March 2018
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Comparison the Postoperation Results of Discectomy with Nucleoplasty in Single Cervical Disc Herniation.

Adv Biomed Res 2018 16;7:29. Epub 2018 Feb 16.

Department of Neurosurgery, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The standard treatment for cervical disc herniation is open discectomy surgery but some of techniques, such as nucleoplasty were applied by neurosurgeons in recent decade. The aim of this study was to compare the postoperation results of open discectomy and nucleoplasty methods in people suffering from single cervical disc herniation.

Materials And Methods: In a clinical trial study that performed during 2012-2013, 70 patients who candidate for neck surgery were selected and randomly divided into two groups. Read More

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http://dx.doi.org/10.4103/abr.abr_159_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840971PMC
February 2018
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