2,730 results match your criteria Diskitis


Vertebral Osteomyelitis and Discitis: "Back" to Susceptibility Testing.

Fed Pract 2020 May;37(5):242-246

is an Internal Medicine Physician; and are Infectious Disease Physicians; all at Naval Medical Center Portsmouth in Virginia. and are Researchers in the Multidrug-Resistant Organism Repository and Surveillance Network at Walter Reed Army Institute of Research in Silver Spring, Maryland.

Genetic testing of anaerobic isolates can be important for proper antimicrobial stewardship to identify the appropriate narrow-spectrum treatment for a polymicrobial infection. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241607PMC

Vertebral osteomyelitis: Clinical, microbiological and radiological characteristics of 116 patients.

Med Clin (Barc) 2020 May 20. Epub 2020 May 20.

Rheumatology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain.

Introduction/objectives: To describe the clinical, radiological and microbiological characteristics of vertebral osteomyelitis patients, analysing the factors that played a role on their outcome.

Patients And Methods: Single-centre retrospective observational study including patients diagnosed with vertebral osteomyelitis, based on the combination of clinical presentation with either a definitive bacteriological diagnosis and/or imaging studies.

Results: 116 adult patients were included with a mean age of 62. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.medcli.2019.12.029DOI Listing

Subacute Presentation of Central Cord Syndrome Resulting from Vertebral Osteomyelitis and Discitis: A Case Report.

Clin Pract Cases Emerg Med 2020 May 23;4(2):267-271. Epub 2020 Apr 23.

Arrowhead Regional Medical Center, Department of Emergency Medicine, Colton, California.

Introduction: Central cord syndrome (CCS) is a clinical syndrome of motor weakness and sensory changes. While CCS is most often associated with traumatic events. There have been few documented cases being caused by abscesses resulting from osteomyelitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5811/cpcem.2019.8.44201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220002PMC

Vague neck pain following a gastrointestinal procedure: a rare case presentation of vertebral osteomyelitis and cervical epidural abscess.

Spinal Cord Ser Cases 2020 May 13;6(1):40. Epub 2020 May 13.

The Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: Vertebral osteomyelitis (VO), spondylodiscitis, and spinal epidural abscesses (SEA) are infectious and inflammatory processes impacting the spine that cause major morbidity and mortality. They require prolonged hospital stays with expensive treatment regimens. Along with acute management, studies have provided evidence highlighting poor long-term outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41394-020-0290-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220930PMC

Adjacent Segment Infection after Lumbar Fusion: A Case Report and the Literature Review.

Case Rep Orthop 2020 20;2020:2163909. Epub 2020 Jan 20.

Department of Orthopedics, Peking University Shougang Hospital, Shijingshang District, Beijing 100144, China.

Introduction: Adjacent segment infective spondylodiscitis is a rare type of surgical spinal infection after lumbar fusion with few reports. We report a further case of adjacent segment infection after three-level lumbar fusion managed successfully with anti-infective therapy and revision surgery. . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/2163909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201821PMC
January 2020

Fluoroscopy-guided percutaneous needle aspiration of posterior epidural abscesses: a report of two cases.

Spinal Cord Ser Cases 2019 May 10;5(1):43. Epub 2019 May 10.

Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, USA.

Introduction: Spinal epidural abscesses are most commonly treated with surgical decompression and antibiotics or in specific instances managed medically with antibiotic therapy alone. Image-guided percutaneous aspiration as an alternative to surgery has only rarely been reported in the literature.

Case Presentation: We report two cases of successful fluoroscopy-guided needle aspiration of posterior epidural abscesses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41394-019-0190-zDOI Listing

Antibiotic-impregnated polymethylmethacrylate strut graft as a treatment of spinal osteomyelitis: case series and description of novel technique.

J Neurosurg Spine 2020 May 8:1-6. Epub 2020 May 8.

1Swedish Neuroscience Institute, Swedish Medical Center, Seattle.

Objective: The surgical treatment of osteomyelitis and discitis of the spine often represents a challenging clinical entity for a multitude of reasons, including progression of infection despite debridement, development of spinal deformity and instability, bony destruction, and seeding of hardware. Despite advancement in spinal hardware and implantation techniques, these aforementioned challenges not uncommonly result in treatment failure, especially in instances of heavy disease burden with enough bony endplate destruction as to not allow support of a modern titanium cage implant. While antibiotic-infused polymethylmethacrylate (aPMMA) has been used in orthopedic surgery in joints of the extremities, its use has not been extensively described in the spine literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2020.3.SPINE191313DOI Listing

A unusual case of multifocal pyogenic abscess formation following ERCP procedure.

BMC Surg 2020 May 6;20(1):92. Epub 2020 May 6.

Department of Surgery A, Galilee Medical Center, Nahariya, Israel.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is essential for managing biliary and pancreatic disorders. Infection is the most morbid complication of ERCP and among the most common causes of ERCP-related death.

Case Presentation: A 69-year-old man presented with right upper quadrant abdominal pain, obstructive jaundice and abnormal liver function tests. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12893-020-00759-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203808PMC

Degenerate-disc infection study with contaminant control (DISC): a multicenter prospective case-control trial.

Spine J 2020 Apr 25. Epub 2020 Apr 25.

School of Medical Sciences, University of New South Wales, Sydney, Australia; Neurosurgical Research Group (NSURG), Sydney, Australia; Department of Neurosurgery, Prince of Wales Public and Private Hospitals, Suite 7, Level 7, Randwick 2031, Australia.

Background: A bacterial cause of disc degeneration has evoked several controversies and, if true, would lead to a major shift in treatment paradigm. Earlier studies analyzing the relationship of bacterial disc infection within a degenerative cohort featured prolonged cultures susceptible to contamination. The degenerate-disc infection study with contaminant control (DISC) trial aims to investigate this theory further by examining infection rates using a non-degenerative control cohort in comparison to a degenerative internal control cohort and a sham cohort (sampling only sterile paraspinal tissue). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.spinee.2020.03.013DOI Listing
April 2020
2.426 Impact Factor

Application of polyetheretherketone cages through minimally invasive oblique retroperitoneal approach for the treatment of lumbar polymicrobial spondylodiscitis: A STROBE-compliant retrospective study with 7 cases.

Medicine (Baltimore) 2020 Apr;99(17):e18594

Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Despite the plethora of evidence in support of the use of structural osseous autograft in lumbar spondylodiscitis, attention has recently been turned to the addition of synthetic materials such as polyetheretherketone (PEEK) to restore anterior vertebral column support.From January 2015 to April 2017, 7 patients with lumbar polymicrobial spondylodiscitis were surgically treated with a minimally invasive oblique retroperitoneal approach to the infected focus. The patients underwent a standard lateral minimally invasive oblique retroperitoneal approach using direct lateral interbody fusion system. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000018594DOI Listing
April 2020
5.723 Impact Factor

CT-guided discitis-osteomyelitis biopsies: needle gauge and microbiology results.

Skeletal Radiol 2020 Apr 18. Epub 2020 Apr 18.

Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street Yawkey 6E, Boston, MA, 02114, USA.

Purpose: To compare the microbiology results and needle gauge for CT-guided biopsies of suspected discitis-osteomyelitis.

Methods: All CT-guided biopsies performed for suspected discitis-osteomyelitis at our institution between 2002 and 2019 were reviewed. Biopsy location, needle type and gauge, microbiology, pathology, and clinical and imaging follow-up were obtained through chart review. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00256-020-03439-3DOI Listing

Development of machine learning and natural language processing algorithms for preoperative prediction and automated identification of intraoperative vascular injury in anterior lumbar spine surgery.

Spine J 2020 Apr 12. Epub 2020 Apr 12.

Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Orthopedic Surgery, Newton Wellesley Hospital, Newton, MA, USA. Electronic address:

Background: Intraoperative vascular injury (VI) may be an unavoidable complication of anterior lumbar spine surgery; however, vascular injury has implications for quality and safety reporting as this intraoperative complication may result in serious bleeding, thrombosis, and postoperative stricture.

Purpose: The purpose of this study was to (1) develop machine learning algorithms for preoperative prediction of VI and (2) develop natural language processing (NLP) algorithms for automated surveillance of intraoperative VI from free-text operative notes.

Patient Sample: Adult patients, 18 years or age or older, undergoing anterior lumbar spine surgery at two academic and three community medical centers were included in this analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.spinee.2020.04.001DOI Listing

Acute Symptomatic Calcific Discitis Mimicking a Septic Spondylodiscitis.

Case Rep Rheumatol 2020 9;2020:5454197. Epub 2020 Mar 9.

Department of Rheumatology, Henri Mondor University Hospital, Paris XII University-UPEC, Créteil, France.

Acute symptomatic calcific discitis is a poorly understood condition that has been mostly reported in children. Cases in adults have been scarcely reported and may mimic an infectious process. Imaging, including computed tomography, can show the disc calcification but might fail to show it because its resorption can occur early after the onset of symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/5454197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085383PMC

Change in Bone CT Attenuation and C-Reactive Protein are Predictors of Bone Biopsy Culture Positivity in Patients with Vertebral Discitis/Osteomyelitis.

Spine (Phila Pa 1976) 2020 Mar 19. Epub 2020 Mar 19.

Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104.

Study Design: Case-control study.

Objective: The objective of this study was to identify the best laboratory and imaging factors to predict bone biopsy culture positivity in the setting of vertebral discitis/osteomyelitis (VDO).

Summary Of Background Data: Good predictors of bone biopsy culture positivity in the setting of VDO are unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BRS.0000000000003504DOI Listing

Tuberculous spondylodiscitis in abscess form.

Rev Soc Bras Med Trop 2020;53:e20190581. Epub 2020 Mar 16.

Department of Radiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0581-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094044PMC

[The Facet Wedge: a minimally invasive technique for posterior segmental intra-articular fusion].

Oper Orthop Traumatol 2020 Mar 16. Epub 2020 Mar 16.

Schön Klinik München Harlaching, Wirbelsäulenzentrum, Akademisches Lehrkrankenhaus der Paracelsus Medizinischen Universität Salzburg, Harlachinger Str. 51, 81547, München, Deutschland.

Objective: Minimally invasive posterior segmental instrumentation and intra-articular fusion with the Facet Wedge device.

Indications: All fusion indications in degenerative disc disease without significant translational instability, postnucleotomy syndrome, spondylarthrosis, discitis.

Contraindications: Translatory instabilities, status after decompression with partial facet joint resection, spondylolysis in the affected segment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00064-020-00659-7DOI Listing

Moraxella catarrhalis discitis: the first reported case.

Intern Med J 2020 Mar;50(3):381-382

Toowoomba Hospital, Toowoomba, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imj.14758DOI Listing

Rare presentation of vertebral discitis, osteomyelitis and polyarticular septic arthritis due to disseminated Neisseria gonorrhea infection.

J Community Hosp Intern Med Perspect 2020 10;10(1):55-59. Epub 2020 Feb 10.

Department of Internal Medicine, OSF Saint Francis Medical Center, Peoria, IL, USA.

Disseminated Neisseria gonorrhea (N. Gonorrhoeae) infection can present with polyarticular involvement. Acute vertebral discitis/osteomyelitis due to this organism infection has been rarely reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/20009666.2019.1710930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034487PMC
February 2020

A minimally invasive, 3D-fluoroscopy-navigation-guided, 3D-controlled pedicle approach in spine surgery: first reliable results and impact on patient safety.

Eur J Trauma Emerg Surg 2020 Mar 2. Epub 2020 Mar 2.

Department of Trauma, Hand and Reconstructive Surgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.

Purpose: Safe pedicle screw placement is a daily challenge to every spine surgeon. Introduction of minimally invasive approaches in spinal surgery led to an impaired facility of inspection of the surgical field increasing the importance of intraoperative imaging and navigation. During the past years, we established a minimally invasive, navigated approach in our clinical setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00068-020-01332-1DOI Listing

Sensing Living Bacteria Using d-Alanine-Derived C Radiotracers.

ACS Cent Sci 2020 Feb 4;6(2):155-165. Epub 2020 Feb 4.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.

Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria . Given the prevalence of d-alanine in peptidoglycan muropeptides, as well as its role in several antibiotic mechanisms, we targeted this amino acid for positron emission tomography (PET) radiotracer development. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acscentsci.9b00743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047270PMC
February 2020

Paraspinal Fat Stranding as an Unexpected Finding on Body Computed Tomography: A Key to Early Detection of Spinal Osteomyelitis.

J Clin Imaging Sci 2020 28;10. Epub 2020 Feb 28.

Department of Radiology, University of Illinois College of Medicine, Chicago, IL, United States.

Objective: At present, early detection of spinal osteomyelitis is a challenge. Patients may present with non-specific symptoms and diagnostic imaging studies may be obtained for seemingly unrelated complaints. Paraspinal fat stranding on body computed tomography (CT) as a sign of osteomyelitis is easily overlooked and has not been reported in the literature to our knowledge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.25259/JCIS_136_2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049891PMC
February 2020

Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine.

Case Rep Rheumatol 2020 10;2020:3218350. Epub 2020 Feb 10.

SUNY Upstate University Hospital, Syracuse, NY-13210, USA.

Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly population and commonly manifests as inflammation of knees, hips, and shoulders. CPPD disease involving the spine has been infrequently encountered in practice and rarely described in the literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/3218350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035534PMC
February 2020

Risk factors associated with poor clinical outcome in pyogenic spinal infections: 5-years' intensive care experience.

J Infect Dev Ctries 2020 Jan 31;14(1):36-41. Epub 2020 Jan 31.

Clinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, Serbia.

Introduction: Management of pyogenic spinal infections (PSI) after the development of neurological deficit has not been specifically addressed in the literature. We aimed to describe real-life clinical outcomes of PSI in patients admitted to an intensive care unit with neurological deficit and identify factors associated with good prognosis.

Methodology: Consecutive patients admitted to ICU with a possible diagnosis of spinal infection over five years' period were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3855/jidc.12260DOI Listing
January 2020

Does bone scintigraphy show Modic changes associated with increased bone turnover?

Eur J Radiol Open 2020 10;7:100222. Epub 2020 Feb 10.

Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland.

Purpose: Our purpose was to evaluate whether Modic changes (MC) revealed in lumbar MRI are associated with increased tracer uptake shown in bone scintigraphy. To our knowledge, this has not previously been studied.

Methods: We included patients with MC shown in lumbar MRI and bone scintigraphy performed within six months before or after MRI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejro.2020.100222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013126PMC
February 2020

Break up the band: Laparoscopic Adjustable Gastric Banding-associated Discitis and Osteomyelitis.

Clin Pract Cases Emerg Med 2020 Feb 21;4(1):72-74. Epub 2020 Jan 21.

University of Iowa Hospitals and Clinics, Department of Emergency Medicine, Iowa City, Iowa.

Obesity is an epidemic that adversely affects millions of Americans. In 2017, the Center for Disease Control and Prevention reported that 93.3 million Americans suffer from obesity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5811/cpcem.2019.11.44879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012566PMC
February 2020

Spondylodiscitis: experience of surgical management of complicated cases after failed antibiotic treatment.

SICOT J 2020 14;6. Epub 2020 Feb 14.

Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut 71511, Egypt.

Introduction: The term Spondylodiscitis (SD) involves infection of the vertebra (Spondylitis), infection of the intervertebral disc (Discitis), or both (Spondylodiscitis). SD represents a diagnostic and therapeutic challenge to any spine surgeon. Any delay in its diagnosis or management may cause serious long-term morbidity or even lead to mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/sicotj/2020002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020778PMC
February 2020

Reduction of Radiation Dose and Scanning Time While Preserving Diagnostic Yield: A Comparison of Battery-Powered and Manual Bone Biopsy Systems.

AJNR Am J Neuroradiol 2020 Mar 6;41(3):387-392. Epub 2020 Feb 6.

From the Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York.

Background And Purpose: There is scarcity of data on the comparative efficacy between bone biopsy drill systems across various types of bone lesions. Our aim was to investigate differences in diagnostic yield, scanning time, and radiation dose between manual and battery-powered bone biopsy systems in CT-guided biopsies of lytic, sclerotic, and infectious bone lesions.

Materials And Methods: This was a retrospective single-center institutional review board-approved study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3174/ajnr.A6428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077903PMC

Effects of Negative Pressure Wound Therapy on Wound Dehiscence and Surgical Site Infection Following Instrumented Spinal Fusion Surgery-A Single Surgeon's Experience.

World Neurosurg 2020 May 28;137:e257-e262. Epub 2020 Jan 28.

Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Orthopedic Surgery, Rochester, Minnesota, USA. Electronic address:

Background: Incisional negative pressure wound therapy (NPWT) is used in many surgical specialties to prevent postoperative dehiscence and surgical site infections (SSIs). However, little is known about the role of incisional NPWT in spine fusion surgery. Therefore, we sought to report a single surgeon's experience using incisional NPWT and describe its effects on dehiscence and SSIs after instrumented spine surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2020.01.152DOI Listing

Diagnosis and management of lumbar spp. discospondylitis using intraoperative cytology and external stabilization in a dog with disseminated infection.

Open Vet J 2019 10 7;9(3):185-189. Epub 2019 Jul 7.

Aúna Especialidades Veterinarias, Valencia 46980, Spain.

Background: Discospondylitis is an infection of the intervertebral disc and adjacent vertebral endplates. The infectious agent is most commonly a bacterial organism and fungal causes are uncommon.

Case Description: A 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4314/ovj.v9i3.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794401PMC
October 2019

Non-infectious thoracic discitis: A diagnostic and management dilemma. A report of two cases with review of the literature.

Clin Neurol Neurosurg 2020 Mar 7;190:105648. Epub 2020 Jan 7.

Department of Neurosurgery, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa, USA.

Discitis/ Osteomyelitis is an inflammatory process involving an intervertebral disc and the adjacent vertebral bodies. Infection is the most common cause of discitis, which is often spontaneous and hematogenous in origin. However, many noninfectious processes affecting the spine such as pseudarthrosis in ankylosing spondylitis, amyloidosis, destructive spondyloarthropathy of hemodialysis, Modic changes type 1, neuropathic arthropathy, calcium pyrophosphate dehydrate (CPPD) spondyloarthropathy and gout can mimic infectious discitis/ osteomyelitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clineuro.2019.105648DOI Listing

MRI and clinical features of acute fungal discitis/osteomyelitis.

Eur Radiol 2020 Apr 3;30(4):2253-2260. Epub 2020 Jan 3.

Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street - YAW 6046 -, Boston, MA, 02114, USA.

Objectives: To compare imaging and clinical features of fungal and Staphylococcus aureus discitis-osteomyelitis (DO) for patients presenting for CT-guided biopsies.

Methods: Our study was IRB-approved and HIPAA-compliant. A group of 11 fungal DO (FG) with MRI within 7 days of the biopsy and a control group (CG) of 19 Staphylococcus aureus DO were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-019-06603-zDOI Listing

Bilateral End-Organ Endophthalmitis in Setting of Serratia marcescens Urosepsis on 18F-FDG PET/CT.

Clin Nucl Med 2020 Mar;45(3):e141-e143

Department of Radiology and Imaging.

Endogenous endophthalmitis is an uncommon infection of the internal tissues of the eye resulting from a bloodborne infection. We present the case of an 89-year-old man with Serratia marcescens urosepsis with multifocal end-organ infection on F-FDG PET/CT including aortitis, splenic abscess, septic arthritis, thoracolumbar discitis-osteomyelitis, and culture-confirmed bilateral endogenous endophthalmitis. Endophthalmitis-related intraconal ocular space uptake was clearly distinguishable from normal conal space extraocular muscle activity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002883DOI Listing

Paediatric spondylodiscitis: a 10-year single institution experience in management and clinical outcomes.

Childs Nerv Syst 2020 May 17;36(5):1049-1054. Epub 2019 Dec 17.

Department of Neurosurgery, Birmingham Children's Hospital, Birmingham, B4 6NH, UK.

Purpose: Discitis in the paediatric population poses diagnostic challenges due to non-specific presenting symptoms and difficulty with expressing pain in non-communicating children. Discitis remains a relatively rare condition in the paediatric population and previous reports are limited to small cohorts. In this article, we report our experience in management of discitis over a 10-year period and review the literature on this topic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00381-019-04470-zDOI Listing
May 2020
1.163 Impact Factor

Minimally Invasive Lateral Retropleural Approach to the Thoracic Spine for Salvage of a Subsided Expandable Interbody Cage.

World Neurosurg 2020 Mar 10;135:58-62. Epub 2019 Dec 10.

Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

Background: Cylindrical expandable cages are commonly used as interbody grafts after cervical, thoracic, or lumbar corpectomy in patients with osteomyelitis. Unfortunately, there is a high incidence of hardware subsidence due to small-diameter footplates. Newer expandable intervertebral cages with large rectangular endcaps use the anatomic strength of the vertebral epiphyseal ring to prevent subsidence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.12.008DOI Listing

Giant Iliac Artery Pseudoaneurysm Mimicking Postoperative Fluid Collection and Diskitis.

World Neurosurg 2020 Apr 6;136:253-257. Epub 2019 Dec 6.

Division of Neuroradiology, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Background: In this report, we describe an extremely rare case of a giant pseudoaneurysm of the internal iliac artery causing marked destructive changes at a disk space and mimicking diskitis-osteomyelitis. Only 2 other cases of pseudoaneurysms extending into the disk space have been reported, and those arose from the aorta and were relatively straightforward to diagnose.

Case Description: Our case is unique because the pseudoaneurysm arose from the internal iliac artery, an artery that is not usually included in the field of view of lumbar magnetic resonance imaging or computed tomography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.11.176DOI Listing

Minimally Invasive Surgery Combining Cortical Bone Trajectory Screws and Pedicle Screws to Treat Spondylodiskitis: Technical Notes and Preliminary Results.

World Neurosurg 2020 Mar 3;135:e333-e338. Epub 2019 Dec 3.

Department of Orthopaedic Surgery, Spine Section, Bone and Joint Research Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan. Electronic address:

Objective: Various surgical techniques for treating spondylodiskitis have been proposed, but the most appropriate surgical treatment remains controversial. In this study, we propose a new hybrid approach combining the use of cortical bone trajectory screws and pedicle screws with the technique of transforaminal lumbar interbody debridement and fusion. With this method, we can shorten the length of the segment that needs to be fixed, minimize the extent of surgical dissection, and reduce the risk of adjacent level degeneration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.11.165DOI Listing

Management of lumbar spondylodiscitis developing after laparoscopic sacrohysteropexy with a mesh: A case report and review of the literature.

Medicine (Baltimore) 2019 Dec;98(49):e18252

Department of Obstetrics and Gynecology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Introduction: Lumbar spondylodiscitis is a rare and severe complication of laparoscopic sacrohysteropexy with a polypropylene mesh. However, a case of lumbar spondylodiscitis following laparoscopic sacrohysteropexy has not been reported so far. We present a case of lumbar spondylodiscitis following laparoscopic sacrohysteropexy with a mesh. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000018252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919408PMC
December 2019

Encephalitis as a complication of a spinal-esophageal fistula due to discitis.

Clin Case Rep 2019 Nov 3;7(11):2190-2193. Epub 2019 Oct 3.

Department of Emergency Medicine College of Medicine Ewha Womans University Seoul Korea.

In patients with back or scapular pain, if there is evidence of neurological symptoms, fever, chills, malaise, or other signs of infection, the work-up should consider the possibility of a spinal-esophageal fistula. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.2471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878085PMC
November 2019

CT-guided discitis-osteomyelitis biopsies with negative microbiology: how many days should we wait before repeating the biopsy?

Skeletal Radiol 2020 Apr 23;49(4):619-623. Epub 2019 Nov 23.

Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street Yawkey 6E, Boston, MA, 02114, USA.

Purpose: To determine the number of days to positive CT-guided biopsy sample culture in patients with discitis-osteomyelitis.

Methods: Our study was IRB approved and HIPAA compliant. All CT-guided biopsies performed for acute discitis-osteomyelitis with positive microbiology between 2002 and 2018 were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00256-019-03344-4DOI Listing

spondylodiscitis with psoas abscess.

BMJ Case Rep 2019 Nov 19;12(11). Epub 2019 Nov 19.

Department of Microbiology, University Hospital Limerick, Limerick, Ireland.

() is a Gram-positive anaerobic cocci, normally found in the oral cavity and rarely causes severe infections. We describe a rare clinical presentation of as spondylodiscitis and psoas abscess with haematogenous spread in an adult patient. MRI lumbar spine detected L2 and L3 spondylodiscitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2019-232040DOI Listing
November 2019

[Spinal infection with spinal cord/cauda equina affection requires emergency handling].

Lakartidningen 2019 Nov 19;116. Epub 2019 Nov 19.

Lund University - Orthopedics Lund/Malmö, Sweden Lund University - Orthopedics Lund/Malmö, Sweden.

Seventeen cases of infections in spinal structures were reported 2010-2017 to the Swedish Health and Social Care Inspectorate (IVO), a government agency responsible for supervising health care, for missed or delayed diagnosis. All patient records were scrutinized in order to find underlying causes and common factors. The delayed diagnoses were equally found among men and women and most frequent in in the age-group 65 to 79 years of age. Read More

View Article

Download full-text PDF

Source
November 2019

Adjacent Level Tuberculous Spondylodiscitis Leading to Proximal Junctional Kyphosis: Rare and Unusual Presentation.

World Neurosurg 2020 Feb 9;134:e808-e814. Epub 2019 Nov 9.

Department of Spine Services, Indian Spinal Injuries Centre, New Delhi, India.

Background: Vertebral osteomyelitis manifesting as a compression fracture misdiagnosed in the setting of steroid-induced or senile osteoporosis is very rare, although such patients are prone to infection or reactivation, as their immune system is exhausted. Spondylodiscitis occurring at adjacent levels following instrumented spinal fusion leading to pathologic fracture and proximal junctional failure, especially caused by tuberculosis, to our knowledge, has not been discussed in the literature.

Methods: In case 1, a 61-year-old woman with osteoporotic T12 collapse was treated with corpectomy, anterior reconstruction, and posterior fixation from T9-L2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.11.007DOI Listing
February 2020

One-stage Debridement via Oblique Lateral Interbody Fusion Corridor Combined with Posterior Pedicle Screw Fixation in Treating Spontaneous Lumbar Infectious Spondylodiscitis: A Case Series.

Orthop Surg 2019 Dec 7;11(6):1109-1119. Epub 2019 Nov 7.

Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Objective: Surgery is indicated when antibiotic treatment fails in pyogenic spondylodiscitis, which is caused by pathogens such as the Staphylococcus species. The aim of the present study was to investigate the efficacy and safety of the oblique lateral interbody fusion (OLIF) corridor approach combined with posterior pedicle screw fixation for treating pyogenic spondylodiscitis.

Methods: This was a retrospective case series study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/os.12562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904647PMC
December 2019

Severity of Salmonella infection among sickle cell diseases pediatric patients: Description of the infection pattern.

Int J Pediatr Adolesc Med 2019 Sep 15;6(3):115-117. Epub 2019 Jun 15.

Pediatric Infectious Diseases Section-children Specialized Hospital, King Fahad Medical City, P.O. Box 59046, Riyadh, 11525, Saudi Arabia.

Introduction: Sickle cell disease (SCD) affects millions worldwide. It has a spectrum of clinical manifestations. However, SCD is more prone to have invasive infection compared with normal individual, and one of the main pathogen of concern is salmonella, where the individual with SCD is more susceptible to salmonella infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpam.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824152PMC
September 2019

Medium-term outcome of posterior surgery in the treatment of non-tuberculous bacterial spinal infection.

J Orthop 2019 Nov-Dec;16(6):569-575. Epub 2019 Jun 19.

Department of Spinal Surgery, Salford Royal NHS Trust, Stott Lane, Salford, M6 8HD, UK.

Objective: to evaluate the outcome of posterior spinal stabilization surgery for the management of bacterial spinal infection.

Methods: 21 patients with bacterial infection were managed surgically with posterior stabilization. Outcome measures included neurological status. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jor.2019.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818358PMC

Management of Pyogenic Spinal Infection, review of literature.

J Orthop 2019 Nov-Dec;16(6):508-512. Epub 2019 Aug 12.

Trauma and Orthopaedics, Manchester Foundation Trust, Southmoor Rd, Wythenshawe, Manchester, M23 9LT, UK.

Objective: To evaluate the available evidence for the management of Pyogenic Spinal Infection (PSI).

Methods And Results: A comprehensive search for the relevant literature published between 1990 and 2018 to evaluate the management of PSI was conducted.Nonoperative management of carefully selected patients for an adequate duration of antibiotics can result in satisfactory outcomes with low recurrence rate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jor.2019.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818362PMC

Establishment and Initial Testing of a Medium-Sized, Surgically Feasible Animal Model for Brucellar Spondylodiscitis: A Preliminary Study.

Biomed Res Int 2019 30;2019:7368627. Epub 2019 Sep 30.

Department of Spine Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Brucellar spondylodiscitis, the most prevalent and significant osteoarticular presentation of human Brucellosis, is difficult to diagnose and usually yields irreversible neurologic deficits and spinal deformities. However, no animal models of Brucellar spondylodiscitis exist, allowing for preclinical investigations. The present study investigated whether intraosseous injection of attenuated vaccine into rabbits' lumbar vertebrae imitates the radiographic and histopathological characteristics of human Brucellar spondylodiscitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/7368627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791230PMC

Intra-discal drain insertion for culture and drainage of pyogenic spondylodiscitis: A one-step diagnostic and therapeutic procedure.

Interv Neuroradiol 2020 Feb 26;26(1):105-110. Epub 2019 Oct 26.

Bar-Ilan Medical School, Tsfat, Israel.

Background: Pyogenic spondylodiscitis is diagnosed in recent years at higher rates due to the aging population, increased survival of chronic and immune suppressed patients, and the higher rate of invasive procedures leading to bacterial seeding or direct contamination of the disc space. Treatment guidelines encourage bacterial sampling before initiation of antibiotic therapy, and drainage of pus collections. We present our experience with percutaneous CT-guided drain insertion into the disc space itself as a one-step procedure for both culturing and subsequent continuous drainage of the infected disc space. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1591019919885557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998002PMC
February 2020

Atypical presentation of Lemierre's syndrome: case report and literature review.

BMC Infect Dis 2019 Oct 21;19(1):868. Epub 2019 Oct 21.

Service of Infectious Diseases, Department of Medicine, Geneva University Hospitals and the University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland.

Background: The classic Lemierre's syndrome refers to a septic thrombosis of the internal jugular vein, usually caused by a Fusobacterium necrophorum infection starting in the oral cavity, and typically complicated by pulmonary emboli. However, unusual forms of the disorder have been rarely reported.

Case Presentation: We describe an unusual case of a previously healthy 58-year-old male with Lemierre's syndrome, manifesting with lumbar pain and fever. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-019-4538-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805316PMC
October 2019
2 Reads