3,036 results match your criteria Diskitis


Discitis due to late-onset mesh infection 14 years after inguinal hernia repair: a case report.

Surg Case Rep 2022 May 25;8(1):102. Epub 2022 May 25.

Digestive Surgery, Yokohama Asahi Chuo General Hospital, 4-20-1, Wakabadai, Asahi-ku, Yokohama, 241-0801, Japan.

Background: Mesh infection after inguinal hernia repair is a very rare complication. The incidence of late-onset mesh infection is approximately 0.1-0. Read More

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Infective Endocarditis Presenting with Embolic Splenic and Renal Infarcts and Spinal Discitis.

Case Rep Infect Dis 2022 14;2022:7183049. Epub 2022 May 14.

Department of Internal Medicine, Riverside University Health System Medical Center, Moreno Valley, California, USA.

(. ) is a Gram-positive, coagulase-negative bacteria that occurs as a normal commensal organism on the skin and may rarely cause native valve endocarditis (NVE). We present a 62-year-old male with type 2 diabetes mellitus, coronary artery disease, and hypertension presenting with fever and abdominal pain. Read More

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Different responses of cervical intervertebral disc caused by low and high virulence bacterial infection: a comparative study in rats.

Bioengineered 2022 May;13(5):12446-12461

Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

The aims of this study were to investigate the outcomes of low- and high-virulence bacterial cervical intervertebral discs (IVDs) infection and its association with cervical IVDs degeneration in rats. A total of 75 clean grade male rats were used to establish the corresponding animal models of low and high virulent bacterial cervical disc infection via an anterior cervical approach, with injection of Propionibacterium acnes (P. acnes) and Staphylococcus epidermidis (S. Read More

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Enterococcal Cervical Discitis Following Transcatheter Aortic Valve Replacement.

Orthop Rev (Pavia) 2022 6;14(1):32323. Epub 2022 Mar 6.

Emergency Medicine, Lakeland Regional Health Medical Center.

Prosthetic valve endocarditis (PVE) is a known transcatheter aortic valve replacement (TAVR). Infective endocarditis is associated with a high incidence of embolic events related to bacterial seeding of various sites through hematogenous spread. This seeding can lead to severe morbidity and mortality and requires an increased incidence of clinical suspicion in at-risk patients to diagnose and treat appropriately. Read More

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An ominous cause of back pain: Vertebral Osteomyelitis.

Orthop Rev (Pavia) 2022 2;14(1):32243. Epub 2022 Mar 2.

Florida State University College of Medicine.

The authors present the case of a patient seen for back pain in the emergency department, initially discharged home with a diagnosis of musculoskeletal pain. He returned a week later and was found to have vertebral osteomyelitis based on a thorough neurologic exam. A review of ominous causes of back pain, including the elusive nature of vertebral osteomyelitis/diskitis is discussed. Read More

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External Review and Validation of a Spinal Epidural Abscess Predictive Score for Clinical Failure.

World Neurosurg 2022 Apr 23. Epub 2022 Apr 23.

Department of Neurological Surgery, University of Wisconsin Hospitals and Clinics, Madison, Wisconsin, USA. Electronic address:

Background: Spinal epidural abscess (SEA) is a rare but serious pathology that may result in delayed neurologic injury despite treatment with antibiotic therapy or surgery. Given this, the development of predictive scores for risk stratification has value in clinical decision making; however, external validation is necessary to understand their generalizability and reliability.

Methods: A retrospective review was conducted of all patients presenting with SEA at a single institution. Read More

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A New Treatment Algorithm That Incorporates Minimally Invasive Surgery for Pyogenic Spondylodiscitis in the Thoracic and Lumbar Spines: The Results of Its Clinical Application to a Series of 34 Patients.

Medicina (Kaunas) 2022 Mar 25;58(4). Epub 2022 Mar 25.

Department of Orthopaedic Surgery, Kansai Medical University Medical Center, 10-15 Fimizono-cho, Moriguchi 570-8507, Japan.

Spinal minimally invasive surgery (MIS) experts at the university hospital worked as a team to develop a new treatment algorithm for pyogenic spondylodiscitis in lumbar and thoracic spines. They modified a flow chart introduced for this condition in a pre-MIS era to incorporate MIS techniques based on their extensive experiences accumulated over the years, both in MIS for degenerative lumbar diseases and in the treatment of spine infections. The MIS procedures incorporated in this algorithm consisted of percutaneous pedicle screw (PPS)-rod fixation and transpsoas lateral lumbar interbody fusion (LLIF). Read More

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The role of discectomy in reducing infectious complications after surgery for lumbar spondylodiscitis.

J Neurol Surg A Cent Eur Neurosurg 2022 Apr 22. Epub 2022 Apr 22.

Neurosurgery, Technical University of Munich, Munich, Germany.

Introduction Surgery for pyogenic spondylodiscitis as an adjunct to antibiotic therapy is an established treatment. However, the technique and extent of surgical debridement remains a matter of debate. Some propagate discectomy in all cases. Read More

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Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs.

PLoS One 2022 20;17(4):e0266663. Epub 2022 Apr 20.

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

Injection drug use poses a public health challenge. Clinical experience indicates that people who inject drugs (PWID) are hospitalized frequently for infectious diseases, but little is known about outcomes when admitted. Charts were identified from local hospitals between 2013-2018 using consultation lists and hospital record searches. Read More

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Spondylodiscitis secondary to : a case report.

J Spine Surg 2022 Mar;8(1):62-69

Department of Pathology, University of Toledo Medical Center, Toledo, Ohio, USA.

Background: Spondylodiscitis secondary to () is a rare primary infection of the spine, with a few case reports highlighted. Treatment of this infection is not well established but here we discuss a case where a patient recovered well following early aggressive surgical intervention and antibiotic treatment.

Case Description: A 32-year-old male presented with a 3-month history of worsening low back pain, Horner's syndrome, dysphagia, lower extremity weakness, and a 5-day history of bowel and bladder incontinence. Read More

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Severe disseminated Veillonella parvula infection including endocarditis, bilateral psoas abscess, discitis, and osteomyelitis but sparing spinal and hip prostheses: a case report.

J Med Case Rep 2022 Apr 20;16(1):157. Epub 2022 Apr 20.

Geriatric Medicine, St John of God Midland Public and Private Hospitals, 1 Clayton St, Midland, WA, 6056, Australia.

Background: Veillonella species are an opportunistically pathogenic commensal anaerobic Gram-negative coccus commonly found in the oral, genitourinary, respiratory, and intestinal tract of humans and some animals. Infection is rare, even in immunocompromised hosts, and has been identified to cause a wide array of different infections, including endocarditis, osteomyelitis, and meningitis.

Case Presentation: An 82-year-old Caucasian male retired ex-gymnast presented to the emergency department with a 2-week history of acute on chronic lower back pain without clear precipitant. Read More

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Septic embolism of the lung due to spondylodiscitis.

Rev Soc Bras Med Trop 2022 8;55:e06622021. Epub 2022 Apr 8.

Bursa City Hospital, Department of Radiology, Bursa, Turkey.

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Diagnostic Yield of Computed Tomography-Guided Procedures for Spondylodiscitis.

Cardiovasc Intervent Radiol 2022 Jun 7;45(6):800-807. Epub 2022 Apr 7.

Interventional Radiology, Department of Radiology, University of São Paulo Medical School, Av. Dr. Enéas Carvalho de Aguiar, 255, Sao Paulo, SP, 05403-000, Brazil.

Purpose: To identify the diagnostic yield and predictive factors for microbiological diagnosis in patients with spondylodiscitis through computed tomography (CT)-guided biopsy or aspiration.

Materials And Methods: A retrospective review of 102 patients with suspected spondylodiscitis who underwent CT-guided procedures in an 8-year period was conducted. Analyzed variables were demographic data, C-reactive protein, pre-biopsy MRI findings, prior antibiotic use, site of biopsy/aspiration, histopathological findings, culture results and radiation dose. Read More

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Humeral Diaphyseal Osteolytic Lesion as the Initial Presentation of Acute Myeloid Leukemia in a Child: A Case Report and Review of the Literature.

Cureus 2022 Mar 3;14(3):e22791. Epub 2022 Mar 3.

Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Gifu, JPN.

It is well known that acute myeloid leukemia (AML) is characterized by lethargy, fever, pallor, and purpura. In children, however, skeletal symptoms may be present at onset in rare cases, and such cases tend to be misdiagnosed as osteomyelitis or septic arthritis. To distinguish acute leukemia from osteomyelitis or bone tumor, the utility of magnetic resonance imaging (MRI) has been discussed. Read More

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The Induced Immune Response in Patients With Infectious Spondylodiscitis: A Prospective Observational Cohort Study.

Front Immunol 2022 14;13:858934. Epub 2022 Mar 14.

Viro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Introduction: Infectious spondylodiscitis is a rare infection of the intervertebral disc and the adjacent vertebral bodies that often disseminates and requires long-term antibiotic therapy. Immunologic profiling of patients with infectious spondylodiscitis could allow for a personalized medicine strategy. We aimed to examine the induced immune response in patients with infectious spondylodiscitis during and after antibiotic therapy. Read More

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Paraspinal soft tissue edema ratio: An accurate marker for early lumbar spine spondylodiscitis on an unenhanced MRI.

Clin Imaging 2022 Jun 14;86:38-42. Epub 2022 Mar 14.

Medical College of Wisconsin Department of Radiology, 8701 Watertown Plank Road, Milwaukee, WI 53226, United States of America. Electronic address:

Purpose: MRI is currently the gold standard imaging modality in the diagnosis of lumbar spine discitis/osteomyelitis. However, even with supportive clinical and laboratory data, the accuracy of MRI remains limited by several degenerative and inflammatory mimics, such that it continues to represent a challenge for radiologists. This study reports a new quantitative imaging marker of lumbar paraspinal soft tissue edema which shows significant accuracy for spondylodiscitis. Read More

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Percutaneous Endoscopic Surgery Alone to Treat Severe Infectious Spondylodiscitis in the Thoracolumbar Spine: A Reparative Mechanism of Spontaneous Spinal Arthrodesis.

Pain Physician 2022 03;25(2):E299-E308

Department of Orthopaedic Surgery, China Medical University Hospital, China Medical University, Taiwan (R.O.C.); Spine Center, China Medical University Hospital, China Medical University, Taiwan (R.O.C.); Department of Sport Medicine, College of Health Care, China Medical University, Taiwan (R.O.C.).

Background: Infective spondylodiscitis has been treated solely with antibiotics based on the pathogen identified. Surgical intervention was used in cases of unidentified pathogens, failed antibiotic treatment, neurological deficit, or instability. The standard surgical procedure was debridement and interbody fusion with a bone graft through the anterior approach, followed by posterior instrumentation. Read More

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spondylodiscitis and epidural abscess successfully treated with unilateral biportal endoscopic discectomy and debridement: a rare case report.

J Int Med Res 2022 Mar;50(3):3000605221085405

Department of Orthopaedic Surgery, Far Eastern Memorial Hospital, New Taipei City.

Spinal epidural abscess (SEA) is a rare but severe infection with potentially devastating consequences. Epidural abscesses caused by serogroup C2 are even rarer and tend to be more invasive with multidrug resistance. Early diagnosis, effective use of antibiotics and surgical intervention are the mainstay strategies for managing SEA, especially for more virulent and multidrug-resistant infections. Read More

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Endoscopic Approach at Two Non-Sequential Levels in Lumbar Discitis.

Cureus 2022 Feb 12;14(2):e22158. Epub 2022 Feb 12.

Neurosurgery, Hospital Naval Marcilio Dias, Rio de Janeiro, BRA.

We report a case of spondylodiscitis in two non-sequential segments of the lumbar spine that was unresponsive to antibiotic treatment instituted and guided by results of blood and urine cultures. A 70-year-old female was admitted to our hospital with complaints of adynamia, low fever, and severe lower back pain that caused difficulty in mobilizing the lower limbs. Spinal tomography and magnetic resonance imaging (MRI) of the lumbar spine suggested L2L3 and L5S1 spondylodiscitis. Read More

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February 2022

Antibiotic-loaded calcium sulfate beads in spinal surgery for patients with spondylodiscitis: a clinical retrospective study.

BMC Musculoskelet Disord 2022 Mar 19;23(1):270. Epub 2022 Mar 19.

Department of Orthopedics, Yantai Affiliated Hospital of Binzhou Medical University, 717 Jinbu Street, Muping District, Yantai, 264000, Shandong Province, People's Republic of China.

Background: Various surgical techniques for treating spondylodiscitis have been proposed, but the optimal surgical treatment remains controversial. In this study, we propose a new procedure that is implanting antibiotic-loaded calcium sulfate (CS) beads into the disc after debridement using the Quadrant channel combined with percutaneous fixation through a single-stage posterolateral approach for the treatment of spondylodiscitis. Thus, the purpose of this study is to assess the safety and efficacy of this procedure. Read More

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Clinical profile, diagnosis, treatment, and outcome of patients with tubercular versus nontubercular causes of spine involvement: A retrospective cohort study from India.

Int J Mycobacteriol 2022 Jan-Mar;11(1):75-82

Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education; Manipal Center for Infectious Diseases, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Background: In tuberculosis (TB) endemic areas, other pyogenic causes of spine involvement may be missed. The study aimed to describe TB and non-TB causes of spine involvement and identify features that can help in differentiating them.

Methods: A retrospective cohort study was conducted to screen the clinical records of all admitted patients (Kasturba Hospital, Manipal) in 2018-20 for a diagnosis of spondylitis and/or sacroiliitis. Read More

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Infectious Spondylodiscitis of the Lumbar Spine: Conservative Antibiotic Therapy vs. Antibiotic Therapy with Surgery, and the Time of Surgery.

Neurol India 2022 Jan-Feb;70(1):155-159

Department of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.

Background: Infectious spondylodiscitis of the lumbar spine is a common serious disease for which evidence-based therapeutic concepts are still lacking.

Objective: This retrospective study compared the impact of the health status of patients on the length of hospital stay with regard to the treatment concept, i.e. Read More

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Georg schmorl prize of the German spine society (DWG) 2021: Spinal Instability Spondylodiscitis Score (SISS)-a novel classification system for spinal instability in spontaneous spondylodiscitis.

Eur Spine J 2022 May 7;31(5):1099-1106. Epub 2022 Mar 7.

Centrum Für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

Purpose: Even though spinal infections are associated with high mortality and morbidity, their therapy remains challenging due to a lack of established classification systems and widely accepted guidelines for surgical treatment. This study's aim therefore was to propose a comprehensive classification system for spinal instability based on the Spinal Instability Neoplastic Score (SINS) aiding spine surgeons in choosing optimal treatment for spontaneous spondylodiscitis.

Methods: Patients who were treated for spontaneous spondylodiscitis and received computed tomography (CT) imaging were included retrospectively. Read More

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Using Probability Estimates to Evaluate a Patient With Weakness.

Cureus 2022 Jan 31;14(1):e21775. Epub 2022 Jan 31.

Hospital Medicine, Northwestern University Feinberg School of Medicine, Chicago, USA.

In this case report, we review how probabilistic reasoning can be implemented in retrospect to refine the diagnostic process. A 67-year-old female with a history of polymyalgia rheumatica (PMR) and a recent dental procedure presented with weakness, falls, and chills ongoing for two weeks. She reported pain in her shoulders and lower back. Read More

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January 2022

vertebral discitis/osteomyelitis in an immunocompetent adult: Case report and literature review.

IDCases 2022 21;27:e01459. Epub 2022 Feb 21.

Cabrini Health, Malvern, Victoria, Australia.

is a gram-positive, pleomorphic bacteria forming part of human oral microflora usually only causing periodontal and dental infections. We describe the case of a 68-year-old immunocompetent male with lumbar vertebral discitis/osteomyelitis caused by . A review of the literature demonstrated seventeen cases of non-dental infection of which only six were in immunocompetent individuals. Read More

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February 2022

Complex Lumbar Spondylodiscitis: A Rare Nosocomial Infection.

Case Rep Infect Dis 2022 16;2022:4378442. Epub 2022 Feb 16.

Department of Infectious Diseases, Santa Barbara Cottage Hospital, Santa Barbara, CA, USA.

Pyogenic spondylodiscitis is rarely caused by complex. is widespread in the environment and recognized as an opportunistic pathogen for patients with cystic fibrosis and immune disorders. A female in her mid-30s with underlying hyperthyroidism, but otherwise immunocompetent, was admitted to the hospital with persistent lower back pain after elective bariatric surgery in Mexico. Read More

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February 2022

Endoscopic treatment of spondylodiscitis: systematic review.

Eur Spine J 2022 Feb 24. Epub 2022 Feb 24.

Neurosurgery Department - Serviço de Neurocirurgia, Centro Hospitalar Universitário Do Algarve, Rua Leão Penedo, 8000-386, Faro, Portugal.

Background: Spondylodiscitis is a severe condition where standalone antibiotic therapy resolves most cases. In refractory infections, open surgery may aid with infection debulking. However, significant morbidity can occur. Read More

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February 2022

PMMA-Cement-PLIF Is Safe and Effective as a Single-Stage Posterior Procedure in Treating Pyogenic Erosive Lumbar Spondylodiscitis-A Single-Center Retrospective Study of 73 Cases.

Bioengineering (Basel) 2022 Feb 15;9(2). Epub 2022 Feb 15.

Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital Bern, University Bern, 3010 Bern, Switzerland.

Background: Surgical treatment for erosive pyogenic spondylodiscitis of the lumbar spine is challenging as, following debridement of the intervertebral and bony abscess, a large and irregular defect is created. Sufficient defect reconstruction with conventional implants using a posterior approach is often impossible. Therefore, we developed the "Cement-PLIF", a single-stage posterior lumbar procedure, combining posterior lumbar interbody fusion (PLIF) with defect-filling using antibiotic-loaded polymethylmethacrylate (PMMA). Read More

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February 2022

Culture Yield in the Diagnosis of Native Vertebral Osteomyelitis: A Single Tertiary Center Retrospective Case Series With Literature Review.

Open Forum Infect Dis 2022 Mar 7;9(3):ofac026. Epub 2022 Feb 7.

Division of Infectious Diseases, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.

Background: Vertebral osteomyelitis is a serious condition that requires prompt diagnosis to avoid delays in proper management. There is no well-defined gold standard for diagnosis. We describe the current diagnostic approach at our institution, with a focus on the yield of image-guided vertebral biopsy. Read More

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Klebsiella Discitis in a 15-Year-Old Male Diagnosed With Plasma Microbial Cell-Free DNA Next-Generation Sequencing Test: A Case Report.

Cureus 2022 Jan 14;14(1):e21237. Epub 2022 Jan 14.

Pediatrics, University of Florida, Pensacola, USA.

Spinal discitis (SD) is a rare condition, particularly in the pediatric population. The course of SD may be acute or chronic, and the non-specificity of symptoms leads to great delays in diagnosis. The most commonly isolated causative organism is whereas gram-negative infections are hardly ever reported in the literature. Read More

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January 2022