4,374 results match your criteria Digestive and Liver Disease[Journal]


Malignant melanoma in the pelvic cavity mimicking a gastrointestinal stromal tumor.

Dig Liver Dis 2019 Apr 16. Epub 2019 Apr 16.

Department of Gastroenterology, Aichi Medical University, Nagakute, Aichi, Japan.

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http://dx.doi.org/10.1016/j.dld.2019.03.017DOI Listing

The role of sphingosine kinase 2 in alcoholic liver disease.

Dig Liver Dis 2019 Apr 16. Epub 2019 Apr 16.

Department of Microbiology and Immunology, Medical College of Virginia and McGuire Veterans Affairs Medical Center, Virginia Commonwealth University, Richmond, Virginia, USA. Electronic address:

Alcoholic liver disease (ALD) is one of the most common liver diseases worldwide. However, the exact mechanisms underlying ALD remain unclear. Previous studies reported that sphingosine kinase 2 (SphK2) plays an essential role in regulating hepatic lipid metabolism. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193052
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http://dx.doi.org/10.1016/j.dld.2019.03.020DOI Listing
April 2019
1 Read

A case of screening colonoscopy using linked-color imaging to detect ulcerative colitis-associated colorectal cancer.

Dig Liver Dis 2019 Apr 15. Epub 2019 Apr 15.

Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.

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http://dx.doi.org/10.1016/j.dld.2019.03.010DOI Listing

FOLFIRINOX-based neoadjuvant chemoradiotherapy for borderline and locally advanced pancreatic cancer: A pilot study from a tertiary centre.

Dig Liver Dis 2019 Apr 15. Epub 2019 Apr 15.

CHU Bordeaux, Department of Radiotherapy, Bordeaux, France; Bordeaux University, INSERM U1035, Bordeaux, France. Electronic address:

Background: Neoadjuvant chemoradiotherapy, potentially relevant to increase resection rate in pancreatic cancer, is still debated.

Aims: To assess tolerance, resection rate and outcomes of patients with non-metastatic pancreatic ductal adenocarcinoma treated by concomitant chemoradiotherapy.

Methods: This monocentric study included all consecutive patients treated from 2010 to 2014 for non-metastatic pancreatic adenocarcinoma. Read More

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http://dx.doi.org/10.1016/j.dld.2019.03.004DOI Listing

Real-life effectiveness of ustekinumab in inflammatory bowel disease patients with concomitant psoriasis or psoriatic arthritis: An IG-IBD study.

Dig Liver Dis 2019 Apr 13. Epub 2019 Apr 13.

IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address:

Background: Few data exist regarding the effectiveness of ustekinumab in inflammatory bowel disease (IBD) patients treated for concomitant psoriasis or psoriatic arthritis.

Aims: to describe the outcomes of IBD patients who received subcutaneous ustekinumab through a dermatological or rheumatological prescription.

Methods: This multicenter, retrospective study included all IBD patients who were started on ustekinumab for concomitant active psoriasis/ psoriatic arthritis, irrespective of IBD activity. Read More

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http://dx.doi.org/10.1016/j.dld.2019.03.007DOI Listing
April 2019
1 Read

Intraductal papillary mucinous neoplasm developed on an ectopic gastric pancreas.

Dig Liver Dis 2019 Apr 10. Epub 2019 Apr 10.

Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Pôle des Pathologies Digestives, Hépatiques et de la Transplantation, Hôpital de Hautepierre-Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193049
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http://dx.doi.org/10.1016/j.dld.2019.03.013DOI Listing
April 2019
1 Read

Adenomyomatosis hyperplasia arising in the bile duct.

Dig Liver Dis 2019 Apr 8. Epub 2019 Apr 8.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193011
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http://dx.doi.org/10.1016/j.dld.2019.03.006DOI Listing
April 2019
3 Reads

EUS-FNB with or without on-site evaluation for the diagnosis of solid pancreatic lesions (FROSENOR): Protocol for a multicenter randomized non-inferiority trial.

Dig Liver Dis 2019 Apr 8. Epub 2019 Apr 8.

Digestive Endoscopy Unit, University Hospital A. Gemelli, IRCCS, Roma, Italy.

Background: Rapid on-site evaluation (ROSE) of cytological specimensacquired with EUS-guided fine needle aspiration (EUS-FNA) represents the most accurate available technique to reach a definitive diagnosis in patients with pancreatic solid masses. Recently, needles with high histological yield have been developed for EUS-guided fine needle biopsy (EUS-FNB), with which the need for ROSE can be potentially overcome.

Aims: The primary aim is to compare the diagnostic accuracy of EUS-FNB with or without ROSE. Read More

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http://dx.doi.org/10.1016/j.dld.2019.03.008DOI Listing
April 2019
1 Read

Acute kidney injury is associated with low factor XIII in decompensated cirrhosis.

Dig Liver Dis 2019 Apr 6. Epub 2019 Apr 6.

University of Virginia, Division of Gastroenterology and Hepatology, Charlottesville, VA, United States.

Background/aims: The coagulation system is known to be rebalanced but fragile in stable cirrhosis. Acute kidney injury (AKI) is common in these patients and associated with an increased bleeding risk. We aimed to assess coagulation parameters in this population. Read More

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http://dx.doi.org/10.1016/j.dld.2019.03.011DOI Listing
April 2019
2 Reads

Mesh plug migration into the small intestine: An unusual cause of chronic anemia.

Dig Liver Dis 2019 Apr 6. Epub 2019 Apr 6.

Department of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.

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http://dx.doi.org/10.1016/j.dld.2019.03.009DOI Listing

Gastric cancer missed at esophagogastroduodenoscopy in a well-defined Spanish population.

Dig Liver Dis 2019 Apr 6. Epub 2019 Apr 6.

Department of Gastroenterology, Institut de Malalties Digestives i Metabòliques, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Background: Although esophagogastroduodenoscopy (EGD) is the standard procedure for the diagnosis of gastric cancer (GC), some GCs are missed. There are no published data on the missed rate of GC in Spain.

Aims: To determine the frequency and characteristics of missed GCs and assess the quality of the EGD in a specific population with GC. Read More

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http://dx.doi.org/10.1016/j.dld.2019.03.005DOI Listing
April 2019
2 Reads

Gitelman syndrome triggered by proton-pump inhibitor use.

Authors:
Antonio Tursi

Dig Liver Dis 2019 Apr 3. Epub 2019 Apr 3.

Gastroenterology Service, ASL BAT, Andria, BT, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.03.001DOI Listing

Cowden syndrome caused by a novel mutation: Endoscopy aided diagnosis.

Dig Liver Dis 2019 Apr 2. Epub 2019 Apr 2.

Department of Gastroenterology and Hepatology, University Hospitals Leuven, Belgium.

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http://dx.doi.org/10.1016/j.dld.2019.03.003DOI Listing
April 2019
1 Read

VALERIO NOBILI.

Authors:
Carlo Agostoni

Dig Liver Dis 2019 Apr;51(4):459

Pediatric Unit, IRCCS "Ca' Granda Ospedale Maggiore Policlinico" Foundation - Policlinico of Milan, Department of Clinical and Community Sciences, DISCCO, Università degli Studi, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193049
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http://dx.doi.org/10.1016/j.dld.2019.03.014DOI Listing
April 2019
1 Read

MicroRNA-194 inhibits cell invasion and migration in hepatocellular carcinoma through PRC1-mediated inhibition of Wnt/β-catenin signaling pathway.

Dig Liver Dis 2019 Mar 1. Epub 2019 Mar 1.

Department of Hepatic Surgery, Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, PR China. Electronic address:

Background: Hepatocellular carcinoma (HCC) is a commonly occurring malignancy accompanied by significant mortality rates. More recently, extensive investigations into microRNA (miRNA) expression profiles have been conducted to identify their ability to inhibit tumors. Thus, this study explored the role of miR-194 in epithelial-mesenchymal transition (EMT), cell invasion and migration through Wnt/β-catenin signaling pathway by binding to protein regulator of cytokinesis 1 (PRC1) in HCC. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.012DOI Listing
March 2019
2 Reads

What Gastroenterologists and Hepatologists should know about organoids in 2019.

Dig Liver Dis 2019 Apr 1. Epub 2019 Apr 1.

Department of Medicine 1, University Hospital, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany. Electronic address:

Most of the research behind new medical advances is carried out using either animal models or cancer cells, which both have their disadvantage in particular with regard to medical applications such as personalized medicine and novel therapeutic approaches. However, recent advances in stem cell biology have enabled long-term culturing of organotypic intestinal or hepatic tissues derived from tissue resident or pluripotent stem cells. These 3D structures, denoted as organoids, represent a substantial advance in structural and functional complexity over traditional in vitro cell culture models that are often non-physiological and transformed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193010
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http://dx.doi.org/10.1016/j.dld.2019.02.020DOI Listing
April 2019
2 Reads

Evaluating the best empirical antibiotic therapy in patients with acute-on-chronic liver failure and spontaneous bacterial peritonitis.

Dig Liver Dis 2019 Mar 31. Epub 2019 Mar 31.

Department of Medicine II, University Hospital, LMU Munich, Germany. Electronic address:

Background/aims: Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of advanced cirrhosis. By studying the susceptibility of isolated organisms and analyzing empirical antibiotic therapy combined with clinical outcomes, we aimed to find an improved empirical antibiotic therapy by considering the individual acute-on-chronic liver failure (ACLF) grade for patients with or without sepsis.

Methods: Clinical outcomes of 182 patients were assessed retrospectively with multivariable regression analysis. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.015DOI Listing
March 2019
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Etiology, presenting features and outcome of children with non-cirrhotic portal vein thrombosis: A multicentre national study.

Dig Liver Dis 2019 Mar 6. Epub 2019 Mar 6.

Paediatric Liver, GI and Transplantation, Hospital Papa Giovanni XXIII Bergamo, Bergamo, Italy. Electronic address:

Objectives: Non-cirrhotic portal vein thrombosis (PVT) is a main cause of portal hypertension in children. We describe the characteristics at presentation and outcome of a cohort of patients with PVT to determine clinical features and predictors of outcome.

Methods: We recorded: (1) Associated factors: prematurity, congenital malformations, neonatal illnesses, umbilical vein catheterization (UVC), deep infections, surgery; (2) congenital and acquired prothrombotic disorders; (3) features at last follow up including survival rate and need for surgery. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.014DOI Listing
March 2019
2 Reads

Development and validation of a new simplified diagnostic scoring system for pediatric autoimmune hepatitis.

Dig Liver Dis 2019 Mar 27. Epub 2019 Mar 27.

Sant Joan de Déu Hospital (HSJD), Department of Pediatric Gastroenterology, Hepatology and Nutrition, Barcelona, Spain; HSJD-HVH Comprehensive Unit of Complex Hepatology and Pediatric Liver Transplantation, Barcelona, Spain. Electronic address:

Background: Children with autoimmune hepatitis (AIH) often exhibit particular features. Accordingly, seven pediatric-specific criteria have been proposed.

Aim: To develop a prediction model based on them, transform it into a scoring system and study its accuracy. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.018DOI Listing
March 2019
2 Reads

Infliximab therapy intensification upon loss of response: Is there an optimal trough level?

Dig Liver Dis 2019 Mar 5. Epub 2019 Mar 5.

Gastroenterology unit, University hospital of Saint Etienne, Saint-Priest-en-Jarez, France.

Introduction: Loss of response (LOR) to infliximab occurs in ∼30% of IBD patients. At time of LOR, lower infliximab-trough-levels (TL), in the absence of anti-drug-antibodies (ATI), have been associated with the need for therapy escalation. Nevertheless, few studies have examined the outcome of infliximab-therapy intensification, based on different TL. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.013DOI Listing

Comparison of FibroTouch and FibroScan for staging fibrosis in chronic liver disease: Single-center prospective study.

Dig Liver Dis 2019 Feb 28. Epub 2019 Feb 28.

Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Background: The aim of this study was to compare the diagnostic accuracy of the FibroTouch and FibroScan in patients with chronic liver disease (CLD) for staging fibrosis.

Methods: A prospective study was conducted in 435 CLD patients between 2014 and 2017. Index tests (FibroTouch, FibroScan, APRI, and FIB-4 score) and a reference standard (liver biopsy) were performed within one week. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.009DOI Listing
February 2019
2 Reads

Different predictors of steatosis and fibrosis severity among lean, overweight and obese patients with nonalcoholic fatty liver disease.

Dig Liver Dis 2019 Mar 27. Epub 2019 Mar 27.

Department of Gastroenterology of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address:

Backgrounds: Non-obese nonalcoholic fatty liver disease (NAFLD) is paradoxically associated with improved metabolic and pathological features at diagnosis but worse prognosis relative to obese NAFLD.

Aim: To compare predictors of disease severity in NAFLD with different body mass index (BMI) categories.

Methods: All 1509 consecutive NAFLD patients were classified as lean (20. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.019DOI Listing
March 2019
1 Read
2.963 Impact Factor

Statin use and pancreatic cancer: A risk assessment.

Authors:
Tomoyuki Kawada

Dig Liver Dis 2019 Feb 28. Epub 2019 Feb 28.

Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.02.011DOI Listing
February 2019

Statin use and pancreatic cancer: a risk assessment. Authors? reply.

Dig Liver Dis 2019 Mar 26. Epub 2019 Mar 26.

Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.02.021DOI Listing

Risk of bacterial pneumonia and pneumococcal infection in youths with celiac disease - A population-based study.

Dig Liver Dis 2019 Feb 28. Epub 2019 Feb 28.

Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy.

Objective: Assess the risk of hospitalizations for bacterial pneumonia or pneumococcal infections, in a cohort of young individuals with celiac disease (CD) compared to matched references.

Study Design: The cohort consists of 213,635 individuals, born in 1989-2012 and resident in Friuli-Venezia Giulia (Italy). Through pathology reports, hospital discharge records or co-payment exemptions, we identified 1294 CD patients and 6470 reference individuals matched by gender and birth year. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.010DOI Listing
February 2019
2 Reads

Mediastinal peripheral T-cell lymphoma presenting with hematemesis.

Dig Liver Dis 2019 Mar 26. Epub 2019 Mar 26.

The University of Texas Medical Branch, Department of Gastroenterology and Hepatology, United States.

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http://dx.doi.org/10.1016/j.dld.2019.02.016DOI Listing
March 2019
1 Read

Noninvasive prediction model for diagnosing gastrointestinal stromal tumors using contrast-enhanced harmonic endoscopic ultrasound.

Dig Liver Dis 2019 Mar 26. Epub 2019 Mar 26.

Department of Internal Medicine, Yonsei University College of Medicine, 03722, Seodaemun-gu, Seoul, Republic of Korea; Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background & Aims: Subepithelial tumors (SETs) are difficult to diagnose accurately without invasive pathological confirmation. We created a noninvasive prediction model for diagnosing gastrointestinal stromal tumors (GISTs) using contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS).

Methods: We retrospectively reviewed 176 patients who underwent CEH-EUS from October 2011 to August 2017. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.017DOI Listing
March 2019
1 Read

Characteristics and consequences of missed gastric cancer: A multicentric cohort study.

Dig Liver Dis 2019 Feb 26. Epub 2019 Feb 26.

Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, University of Alcala, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS),Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III, Spain.

Background: Missed gastric cancer (MGC) is poorly documented in Mediterranean populations.

Aims: (1) To assess the rate, predictors and survival of MGC. (2) To compare MGC and non-MGC tumors. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.006DOI Listing
February 2019

Percutaneous recanalization of a segmental inferior vena cava occlusion in a patient with situs viscerum inversus and symptomatic Budd-Chiari syndrome.

Dig Liver Dis 2019 Feb 22. Epub 2019 Feb 22.

Radiology Unit, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IRCCS-ISMETT), Palermo, Italy.

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http://dx.doi.org/10.1016/j.dld.2019.02.007DOI Listing
February 2019
2 Reads

Sequence of acquisition of self-management skills to follow a gluten-free diet by adults with celiac disease.

Dig Liver Dis 2019 Feb 26. Epub 2019 Feb 26.

Division of Gastroenterology, Boston Children's Hospital, United States. Electronic address:

Background: Celiac disease (CD) treatment is lifelong adherence to a gluten-free diet (GFD), requiring mastery of numerous skills to maintain health.

Aims: To assess the rate of self-management skill acquisition following diagnosis, and the influence of demographic factors on this rate.

Methods: Patients attending a celiac center were invited to complete an anonymous survey which reported demographic information and time for mastery of self-management skills relevant to CD. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.008DOI Listing
February 2019
7 Reads

Prospective comparative study of endoscopic ultrasonography-guided fine-needle biopsy and unroofing biopsy.

Dig Liver Dis 2019 Feb 19. Epub 2019 Feb 19.

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background And Aim: Adequate tissue acquisition is important in making treatment decisions for patients with upper gastrointestinal subepithelial tumors (SETs). This study aimed to compare the outcomes of endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) with those of the unroofing biopsy technique.

Methods: This study was a single-center, prospective comparative study conducted at Severance Hospital, Yonsei University College of Medicine. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.028DOI Listing
February 2019

Real-world efficacy of adalimumab and infliximab for refractory intestinal Behçet's disease.

Dig Liver Dis 2019 Feb 19. Epub 2019 Feb 19.

Department of Gastroenterology, Aichi Medical University School of Medicine, Nagakute, Aichi-ken, Japan.

Background: Anti-tumor necrosis factor-α agents are important for managing refractory intestinal Behçet's disease. Few studies have reported the efficacy of anti-tumor necrosis factor-α monoclonal antibodies for intestinal Behçet's disease due to its rarity.

Aims: The aim was to examine the efficacy of anti-tumor necrosis factor-α antibodies for intestinal Behçet's disease in real-world practice. Read More

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http://dx.doi.org/10.1016/j.dld.2018.10.024DOI Listing
February 2019
4 Reads

Use of biosimilars in inflammatory bowel disease: A position update of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD).

Dig Liver Dis 2019 Feb 19. Epub 2019 Feb 19.

IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address:

The first infliximab biosimilar for the treatment of inflammatory bowel disease (IBD) was introduced in 2013, and today eight anti-TNF alpha biosimilars (three for infliximab and five for adalimumab) have been approved and licensed by the European Medicines Agency. Biosimilars present great potential in terms of cost saving and possible consequential reinvestment in the health care system. The increasing knowledge about the process of biosimilar development and use in IBD and the publication of many prospective clinical studies and real-life clinical experiences have progressively changed the point of view of IBD physicians. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.004DOI Listing
February 2019
6 Reads

Transjugular aspiration liver biopsy performed by hepatologists trained in HVPG measurements is safe and provides important diagnostic information.

Dig Liver Dis 2019 Feb 12. Epub 2019 Feb 12.

Division of Gastroenterology & Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; Vienna Hepatic Hemodynamic Laboratory, Medical University of Vienna, Vienna, Austria. Electronic address:

Background: Transjugular liver biopsy (TJLB) represents an alternative to percutaneous liver biopsy especially in patients with impaired coagulation and ascites.

Aims: To describe safety and diagnostic yield of aspiration TJLB performed by hepatologists experienced in hepatic venous pressure gradient (HVPG) measurements.

Methods: 445 TJLB of 399 patients between 01/2007-12/2016 were retrospectively assessed. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.020DOI Listing
February 2019
1 Read

Low-dose biologics to treat inflammatory bowel disease. Ready for prime time?

Authors:
Dario Sorrentino

Dig Liver Dis 2019 Apr 18;51(4):609-610. Epub 2019 Feb 18.

IBD Center, Division of Gastroenterology, Virginia Tech Carilion School of Medicine, Roanoke, VA, USA; Department of Clinical and Experimental Medical Sciences, University of Udine School of Medicine, Udine, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193006
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http://dx.doi.org/10.1016/j.dld.2019.02.005DOI Listing
April 2019
4 Reads

On the origin of "indolent" and "aggressive" non-functioning pancreatic neuroendocrine tumour… genetically unrelated or close relative?

Dig Liver Dis 2019 Feb 21. Epub 2019 Feb 21.

Hôpital Cochin, Department of Hepato-Pancreato-Biliary and Endocrine Surgery, AP-HP, Paris, France; Université Paris Descartes, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.02.003DOI Listing
February 2019

Resection rates and safety profile of cold vs. hot snare polypectomy in polyps sized 5-10 mm and 11-20 mm.

Dig Liver Dis 2019 Apr 11;51(4):536-541. Epub 2019 Feb 11.

Department of Internal Medicine III, Division of Gastroenterology & Hepatology, Medical University of Vienna, Austria; Austrian Society of Gastroenterology and Hepatology (OEGGH): Quality assurance working group, Austria. Electronic address:

Background And Aims: Hot snare (HS) is widely used for the resection of adenomas >5 mm. The cold snare (CS) has a better safety profile and is more cost-effective. The aims of this study were to evaluate effectiveness and safety of CS polypectomy (CSP) compared to HS polypectomy (HSP) for adenomas sized 5-10 mm and 11-20 mm. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.007DOI Listing
April 2019
2 Reads

Incidence, prevalence, and causes of death of patients with autoimmune hepatitis: A nationwide register-based cohort study in Finland.

Dig Liver Dis 2019 Feb 10. Epub 2019 Feb 10.

Department of Gastroenterology, Helsinki University Hospital, Helsinki University, Helsinki, Finland.

Background: Epidemiological studies of autoimmune hepatitis are scarce and often based on single centre registries.

Aims: We conducted a nationwide register study of incidence, prevalence, survival, and causes of death of autoimmune hepatitis patients in Finland.

Methods: Autoimmune hepatitis cases 1995-2015 were retrieved from the national database of special reimbursements for drugs costs. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.015DOI Listing
February 2019
1 Read

Diagnosis of chronic anaemia in gastrointestinal disorders: A guideline by the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Society of Paediatric Gastroenterology Hepatology and Nutrition (SIGENP).

Dig Liver Dis 2019 Apr 11;51(4):471-483. Epub 2019 Feb 11.

Oncological Gastroenterology Division, Centro di Riferimento Oncologico (CRO) IRCCS, Aviano.

Anaemia is a common pathologic condition, present in almost 5% of the adult population. Iron deficiency is the most common cause; other mechanisms can be involved, making anaemia a multi-factorial disorder in most cases. Anaemia being a frequent manifestation in the diseases of the gastrointestinal tract, patients are often referred to gastroenterologists. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.022DOI Listing
April 2019
1 Read

Endoscopy in acute variceal bleeding: Not always the sooner, the better?

Dig Liver Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Biomedical and Clinical Sciences, University of Milan, Gastroenterology and Endoscopy Unit, ASST Fatebenefratelli Sacco, Milan, Italy.

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http://dx.doi.org/10.1016/j.dld.2019.01.025DOI Listing
February 2019

DAAs prevent HCC - the plot thickens.

Dig Liver Dis 2019 Apr 11;51(4):460-461. Epub 2019 Feb 11.

Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine, Transplant Hepatologist, Avera McKennan University Health Center and Transplant Institute, Chief Clinical Research Affairs, Avera Transplant Institute and Human Genetics Research Institute, 1315 S Cliff Ave, Plaza 3 Suite 1200, Sioux Falls SD 57105 USA. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.01.027DOI Listing

Risk factors and timing for colectomy in chronically active refractory ulcerative colitis: A systematic review.

Dig Liver Dis 2019 Feb 6. Epub 2019 Feb 6.

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy.

Background: In patients with chronic refractory ulcerative colitis (UC) the precise timing for indication to colectomy is unclear.

Aims: We performed a systematic review of the literature on the risk factors for colectomy in patients with chronic refractory UC in the biologic era.

Methods: PubMed Central/Medline and Embase were systemically searched for records published between January 2000 and December 2017. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.018DOI Listing
February 2019
2 Reads

Impact of inflammatory bowel diseases on working life: A French nationwide survey.

Dig Liver Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Gastroenterology, Grand-Sud Polyclinic, Nîmes, France.

Background: Inflammatory bowel diseases (IBD) affect working-age patients. Data was lacking concerning the impact on working life.

Aims: The French IBD patient association conducted a nationwide survey to assess the burden of IBD at work. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.024DOI Listing
February 2019
1 Read

Esophageal diverticulum after peroral endoscopic myotomy: Think about it if the symptoms change.

Dig Liver Dis 2019 Feb 11. Epub 2019 Feb 11.

Institut des Maladies de l'Appareil Digestif, IMAD, CHU Nantes, Hôpital Hôtel-Dieu, Nantes, France; Service des Maladies de l'Appareil Digestif, CHU Rennes Pontchaillou, Rennes, France; Service d'Explorations Fonctionnelles Digestives, CHU Rennes Pontchaillou, Rennes, France; Université de Rennes 1, CIC1414, groupe INPHY, CHU Rennes Pontchaillou, Rennes, France. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.01.023DOI Listing
February 2019

Hospitalization trends of the Inflammatory Bowel Disease landscape: A nationwide overview of 16 years.

Dig Liver Dis 2019 Feb 6. Epub 2019 Feb 6.

IBD Portuguese Group (GEDII), Porto, Portugal; São João Hospital, Gastroenterology Department, Porto, Portugal; Unit of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Portugal; MedInUP - Center for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal. Electronic address:

Introduction: In this study, we aimed to determine the hospitalization rates of Inflammatory Bowel Disease (IBD) in a southern-european country and its associated charges over a period of 16 years.

Methods: We identified all discharges with a primary diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) between 2000 and 2015 in data provided by the Central Administration of Health Services (ACSS). National estimates of hospitalization rates were assessed and adjusted to gender, age, population, and hospitalizations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193005
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http://dx.doi.org/10.1016/j.dld.2019.01.016DOI Listing
February 2019
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FXR deficiency and alcoholic liver disease: Tissue is the issue.

Dig Liver Dis 2019 Apr 7;51(4):577-578. Epub 2019 Feb 7.

Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine, Transplant Hepatologist, Avera McKennan University Health Center and Transplant Institute, Chief Clinical Research Affairs, Avera Transplant Institute and Human Genetics Research Institute, 1315 S Cliff Ave, Plaza 3 Suite 1200, Sioux Falls, SD 57105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.01.014DOI Listing

The crucial need of internal control validation in the normalization of circulating microRNAs.

Dig Liver Dis 2019 Apr 7;51(4):610-611. Epub 2019 Feb 7.

School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.01.009DOI Listing
April 2019
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Transjugular Intrahepatic Portosystemic Shunt does not affect the efficacy and safety of direct-acting antivirals in patients with advanced cirrhosis: A real-life, case-control study.

Dig Liver Dis 2019 Feb 7. Epub 2019 Feb 7.

Department of Experimental and Clinical Medicine, University of Florence, Italy; Research Center Denothe, University of Florence, Italy. Electronic address:

Background: Transjugular Intrahepatic Portosystemic Shunt (TIPS) is a well-established treatment for complications of portal hypertension.

Aims: To analyze the impact of TIPS on virologic response and safety profile in patients treated with direct-acting antivirals (DAAs).

Methods: We analyzed data from HCV-positive cirrhotic patients treated with DAAs. Read More

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http://dx.doi.org/10.1016/j.dld.2018.11.015DOI Listing
February 2019
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2.963 Impact Factor

O6-methylguanine-DNA methyltransferase (MGMT) status in neuroendocrine tumors: a randomized phase II study (MGMT-NET).

Dig Liver Dis 2019 Apr 14;51(4):595-599. Epub 2019 Feb 14.

Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France. Electronic address:

Introduction: Neuroendocrine tumors (NETs) are rare, but their incidence is rising. Alkylating agents (ALKY), temozolomide and streptozotocin, are the main chemotherapies used for advanced pancreatic NETs. According to retrospective data, O6-methylguanine-DNA methyltransferase (MGMT) status appears to be a predictive factor of the response to ALKY. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.001DOI Listing
April 2019
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Reply to: "The crucial need of internal control validation in the normalization of circulating microRNAs".

Dig Liver Dis 2019 Apr 14;51(4):611-612. Epub 2019 Feb 14.

Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China; Division of Infectious Diseases, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, Sichuan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.02.002DOI Listing
April 2019
2 Reads