1,294 results match your criteria Diffuse Idiopathic Skeletal Hyperostosis

Outcomes following conservative treatment of extension fractures in the setting of diffuse idiopathic skeletal hyperostosis: is external orthosis alone a reasonable option?

J Neurosurg Spine 2022 Aug 5:1-5. Epub 2022 Aug 5.

Objective: Extension fractures in the setting of diffuse idiopathic skeletal hyperostosis (DISH) represent highly unstable injuries. As a result, these fractures are most frequently treated with immediate surgical fixation to limit any potential risk of associated neurological injury. Although this represents the standard of care, patients with significant comorbidities, advanced age, or medical instability may not be surgical candidates. Read More

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Zero-Profile Implant System for Treatment of Dysphagia Caused by Noncontiguous Anterior Cervical Osteophytes-A Case Report with Literature Review.

Orthop Surg 2022 Aug 4. Epub 2022 Aug 4.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: Esophageal cervical spondylosis is a rare type of cervical spondylosis which causes dysphagia. Surgical osteophyte resection is taken when conservative treatment does not respond. However, few reports on its operation and postoperative follow-up. Read More

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Percutaneous kyphoplasty for the treatment of diffuse idiopathic skeletal hyperostosis with vertebral fractures: A case report and treatment review.

Front Surg 2022 15;9:922139. Epub 2022 Jul 15.

Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.

Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic metabolic condition characterized by new bone formation mainly at the anterolateral spine. Surgery such as screw fixation is commonly used for DISH patients who also suffer from vertebral fractures. In this case report, we share a DISH case with lumbar vertebral fracture and osteoporosis who underwent percutaneous kyphoplasty plus braces and medication. Read More

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Surgical Treatment of Dysphagia Secondary to Anterior Cervical Osteophytes Due to Diffuse Idiopathic Skeletal Hyperostosis.

Medicina (Kaunas) 2022 Jul 13;58(7). Epub 2022 Jul 13.

Department of Neurosurgery, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul 05278, Korea.

Diffuse idiopathic skeletal hyperostosis (DISH) is an ossifying and ankylosing skeletal condition that can be associated with DISH-related dysphagia in the case of cervical involvement. In contrast to most cases of dysphagia, which are managed conservatively, DISH-related dysphagia can be discouraging due to the progressive nature of DISH. We report two cases of DISH-related dysphagia that were treated with the surgical removal of osteophytes via an anterolateral approach. Read More

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Prognostic Factors and Optimal Surgical Management for Lumbar Spinal Canal Stenosis in Patients with Diffuse Idiopathic Skeletal Hyperostosis.

J Clin Med 2022 Jul 16;11(14). Epub 2022 Jul 16.

Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan.

Lumbar spinal canal stenosis (LSS) and diffuse idiopathic skeletal hyperostosis (DISH) tend to develop in the elderly, resulting in an increased need for lumbar surgery. However, DISH may be a risk factor for poor clinical outcomes following lumbar decompression surgery, especially in patients with DISH extending to the lumbar segment (L-DISH). This study aimed to identify the prognostic factors of LSS with L-DISH and propose an optimal surgical management approach to improve clinical outcomes. Read More

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Impact of Diffuse Idiopathic Skeletal Hyperostosis on Clinico-Radiological Profiles and Prognosis for Thoracic Ossification of Ligamentum Flavum-Myelopathy: A Propensity-Matched Monocentric Analysis.

Diagnostics (Basel) 2022 Jul 7;12(7). Epub 2022 Jul 7.

Department of Orthopaedics, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing 100191, China.

Background: Diffuse idiopathic skeletal hyperostosis (DISH) has been evaluated as a potential risk factor of poor surgical outcomes for lumbar spinal stenosis, whereas the influence of DISH on neuroimaging characteristics and postoperative prognosis of patients with thoracic myelopathy has not been established. Therefore, this study aimed to shed light on this issue.

Methods: A monocentric study enrolled 167 eligible patients with thoracic ossification of ligamentum flavum (TOLF), who were followed up for at least 2 years. Read More

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Prognostic models for the development of diffuse idiopathic skeletal hyperostosis.

Folia Med (Plovdiv) 2022 Jun;64(3):450-458

Medical University of Plovdiv, Plovdiv, Bulgaria.

Introduction: Diffuse idiopathic skeletal hyperostosis (DISH) is a common worldwide disease in adults over 50 years of age. The clinical diagnosis at the beginning of the disease is very difficult, even impossible, without typical symptoms and image changes. Mathematical models for searching risk factors include analysing medical history data, comorbidities, biochemical and instrumental results. Read More

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Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study).

J Clin Med 2022 Jun 27;11(13). Epub 2022 Jun 27.

Department of Orthopedic Surgery, University of Yamanashi, Chuo 409-3898, Japan.

Background: The purpose of this study was to clarify the clinical features of ossification of the posterior longitudinal ligament (OPLL) and extreme ossification at multiple sites.

Methods: This prospective study involved patients with a diagnosis of cervical OPLL at 16 institutions in Japan. Patient-reported outcome measures, including responses on the Japanese Orthopaedic Association (JOA) Cervical Myelopathy Evaluation Questionnaire (JOA-CMEQ), JOA Back Pain Evaluation Questionnaire (JOA-BPEQ), and visual analog scale pain score, were collected to investigate clinical status. Read More

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Operative Outcomes After Cervical Diffuse Idiopathic Skeletal Hyperostosis Fracture in the Elderly.

Int J Spine Surg 2022 Jun;16(3):435-441

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Background: Cervical diffuse idiopathic skeletal hyperostosis (DISH) fractures are frequently unstable and carry significant risk of neurologic injury and death. Most patients with DISH fractures are elderly (>70 years) with significant comorbidities. We assessed factors that contribute to outcomes in elderly patients with cervical DISH fractures. Read More

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Diffuse Idiopathic Skeletal Hyperostosis.

Patrick Graham

Orthop Nurs 2022 May-Jun 01;41(3):237-239

Patrick Graham, MSN, RN, APRN/ANP-BC, Banner University Medical Center Tuscon, Tuscon, AZ.

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Rib hyperostosis: a benign entity with suspicious imaging features.

Radiol Case Rep 2022 Sep 17;17(9):2987-2990. Epub 2022 Jun 17.

Penn State Health Milton S. Hershey Medical Center, Department of Radiology, 500 University Drive, Hershey, PA 17033, USA.

Rib hyperostosis has previously been described in conjunction with disorders causing excessive vertebral ossification due to osseous bridging across the costovertebral joint, such as in diffuse idiopathic skeletal hyperostosis. Hyperostosis is believed to be a reactive process due to altered forces across the affected rib as bridging osteophytes decrease mobility at the respective costovertebral joint. The imaging characteristics of rib hyperostosis can be highly suspicious for malignancy. Read More

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September 2022

Inflammation, new bone formation and aorta.

Int J Rheum Dis 2022 Jun 13. Epub 2022 Jun 13.

Department of Rheumatology, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.

Objectives: This study describes the characteristics of vertebral osteophytes in different inflammatory and non-inflammatory diseases aiming to reflect the aortic-vertebrae interaction.

Methods: We conducted a cross-sectional study including 4 group of patients, ankylosing spondylitis (AS, n = 52), Takayasu's arteritis (TKA, n = 31), diffuse idiopathic skeletal hyperostosis (DISH, n = 30), coronary artery disease (CAD, n = 10), 100 and also age-matched healthy controls (HC, n = 143). All subjects underwent a chest computed tomography scan and images of the upper and lower border of 7 adjacent thoracic vertebrae (T5 to T12) were captured. Read More

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Zenker's Diverticulum in Forestier Disease: Chance or Causality?

Iran J Otorhinolaryngol 2022 Mar;34(121):107-112

Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy.

Introduction: Zenker's diverticulum is an acquired sac-like outpouching of the mucosa and submucosa layers originating at the pharyngoesophageal junction. The predominant symptom of Zenker's diverticulum is dysphagia. Videofluoroscopy confirms the diagnosis. Read More

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The Prevalence and Characteristics of Diffuse Idiopathic Skeletal Hyperostosis (DISH): A Cross-Sectional Study of 1519 Japanese Individuals.

Diagnostics (Basel) 2022 Apr 27;12(5). Epub 2022 Apr 27.

Department of Orthopaedic Surgery, Kagawa Prefectural Central Hospital, 2-1, Asahi-Machi 1-Chome, Takamatsu 760-8557, Japan.

Background: Diffuse idiopathic skeletal hyperostosis (DISH) is a pathology characterized by enthesis ossification, but there have been few reports on epidemiological surveys. This report presents a cross-sectional survey of DISH from thoracic to sacral spine in patients at the tertiary emergency medical center.

Methods: The patients were divided into DISH (+) group and DISH (-) group for a retrospective comparative study. Read More

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Perioperative risk stratification of spine trauma patients with ankylosing spinal disorders: a comparison of 3 quantitative indices.

J Neurosurg Spine 2022 May 27:1-7. Epub 2022 May 27.

1Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota; and.

Objective: Patients with ankylosing spinal disorders (ASDs), including ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH), have been shown to experience significantly increased rates of postoperative complications. Despite this, very few risk stratification tools have been validated for this population. As such, the purpose of this study was to identify predictors of adverse events and mortality in ASD patients undergoing surgery for 3-column fractures. Read More

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Subchondral bone attenuation coefficient utility of the sacroiliac margins to differentiate spondyloarthritis and osteitis condensans ilii.

RMD Open 2022 05;8(1)

Department of Rheumatology, CHU Besancon, Besancon, France

Introduction: Differentiating ankylosing spondylitis (AS) from osteitis condensans ilii (OCI) remains challenging for clinicians. The aim of this study was to determine whether Subchondral Bone Attenuation Coefficient of the SacroIliac margins (SBAC-SI) is different in AS, OCI and diffuse idiopathic skeletal hyperostosis (DISH).

Methods: A monocentric retrospective observational study was performed at the University Hospital of Besançon. Read More

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Intraoperative Traction May Induce Acute Onset Dysphagia With Diffuse Idiopathic Skeletal Hyperostosis After Anterior Cervical Discectomy.

Korean J Neurotrauma 2022 Apr 17;18(1):126-131. Epub 2022 Feb 17.

Department of Neurosurgery, VHS Medical Center, Seoul, Korea.

Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic bone-forming disease, and its pathogenesis remains unknown. Moreover, the incidence of DISH increases with age. DISH may be an age-related disorder that occurs more frequently in degenerative spines than in healthy spines. Read More

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A case of cervical OPLL and DISH mimicking stroke.

Surg Neurol Int 2022 22;13:158. Epub 2022 Apr 22.

Department of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.

Background: Ossification of the posterior longitudinal ligament (OPLL) is a progressive disorder that mostly involves the cervical spine. It is more prevalent in East Asian countries. Patients typically present with the gradual onset of myelopathy, while about 5% show rapid progression. Read More

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Response to: Risk Factors Affecting Cage Retropulsion into the Spinal Canal Following Posterior Lumbar Interbody Fusion: Association with Diffuse Idiopathic Skeletal Hyperostosis.

Asian Spine J 2022 Apr 25;16(2):309-310. Epub 2022 Apr 25.

Department of Orthopaedic Surgery, Restorative Medicine of Neuro-Musculoskeletal System, School of Medicine, Fujita Health University, Nagoya, Japan.

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The Covid 19 Pandemic Effect on the Epidemiology of Thoracolumbar Fractures Presenting to the Emergency Department in Patients Above 65 years Old.

Geriatr Orthop Surg Rehabil 2022 23;13:21514593221098828. Epub 2022 Apr 23.

Department of Orthopedic Surgery, Wolfson Medical Center, Holon, Israel, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Introduction: Studies investigating the Covid-19 Pandemic's orthopedic aspects are accumulating, including reports on a 10-33% decrease in hip fracture incidence alongside shorter times to surgery. Osteoporotic vertebral compression fractures (VCF) have not yet been discussed. This study evaluated the effect of the Covid-19 pandemic's first wave on VCF in the elderly. Read More

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Bone Fusion Morphology after Circumferential Minimally Invasive Spine Surgery Using Lateral Lumbar Interbody Fusion and Percutaneous Pedicle Screws without Bone Grafting in the Thoracic Spine: A Retrospective Study.

Medicina (Kaunas) 2022 Mar 30;58(4). Epub 2022 Mar 30.

Department of Orthopedic Surgery, Kansai Medical University, Osaka 573-1191, Japan.

: This study aimed to investigate the process and morphology of thoracic and lumbosacral bone fusion in patients with adult spinal deformity (ASD) who underwent circumferential minimally invasive spine surgery (CMIS) by lateral lumbar interbody fusion (LLIF) and percutaneous pedicle screws (PPSs) without bone grafting in the thoracic spine and who have risk factors for bone fusion failure in the thoracic spine. : This retrospective study included 61 patients with spinal deformities (46 women and 15 men) who underwent CMIS with LLIF and PPSs at our hospital after 2016 and completed a 3-year postoperative follow-up. The rate and morphology of bone fusion and rod fracture rate in the thoracic and lumbosacral vertebrae were evaluated. Read More

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Difficult transesophageal echocardiography probe insertion due to cervical diffuse idiopathic skeletal hyperostosis.

Ann Card Anaesth 2022 Apr-Jun;25(2):246-247

Department of Anesthesiology, Kumamoto University Hospital, Kumamoto, Japan.

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Treatment of Unstable Sacral Fracture with Minimally Invasive Spinopelvic Posterior Fixation and an Internal Anterior Fixator in a 95-Year-Old Patient with Diffuse Idiopathic Skeletal Hyperostosis: A Case Report.

Takeshi Sasagawa

J Orthop Case Rep 2021 Sep;11(9):43-46

Department of Orthopedics Surgery, Toyama Prefectural Central Hospital, Toyama City, Japan.

Introduction: Spinal fractures related to diffuse idiopathic skeletal hyperostosis (DISH) are almost always caused by a long lever arm, so treatment of the fractures requires stabilization of long segments of the spine. Treatment of unstable sacral fractures in DISH patients with ankylosis of the sacroiliac joints requires a treatment strategy that includes a consideration of the condition of the spine. This article is the first report of an unstable sacral fracture in a patient with DISH. Read More

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September 2021

No correlation between diffuse idiopathic skeletal hyperostosis and coronary artery disease on computed tomography using two different scoring systems.

Acta Radiol 2022 Apr 4:2841851221090890. Epub 2022 Apr 4.

Department of Diagnostic Imaging, 26744Sheba Medical Center, Tel Hashomer, Israel, affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: An association between diffuse idiopathic skeletal hyperostosis (DISH) and a history of coronary artery disease (CAD) was previously reported.

Purpose: To investigate the association between DISH and CAD as assessed using the coronary artery calcification score (CACS) and the CAD-Reporting and Data System (CAD-RADS) score in patients with symptomatic chest pain.

Material And Methods: Consecutive cardiac CT scans performed before and after IV contrast administration were evaluated for CACS (Agatston method), CAD-RADS, and the presence of DISH. Read More

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An unusual presentation of thoracic diffuse idiopathic skeletal hyperostosis (DISH) and video-assisted thoracoscopic surgery (VATS).

Int J Surg Case Rep 2022 Apr 30;93:106993. Epub 2022 Mar 30.

Department of Orthopaedics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address:

Introduction And Importance: Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier's disease and Forestier and Rotes-Querol disease, is a systemic condition characterized by calcification and ossification of ligaments and entheses which often mainly affects the thoracic spine. Anterior osteophyte compression of the esophagus resulting in dysphagia and dyspepsia is extremely rare in symptomatic thoracic DISH.

Case Presentation: A 72-year-old male presented with dyspepsia and dysphagia for 10 months. Read More

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Osteophytes' position in subjects with DISH and right-sided aorta: verification of the "aortic pulsation protective effect" theory.

Rheumatology (Oxford) 2022 Mar 30. Epub 2022 Mar 30.

Department of Diagnostic Imaging, Sheba Medical Center, affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: To validate on a large cohort with right-sided aorta the theory that thoracic right-sided flowing osteophytes in diffuse idiopathic skeletal hyperostosis (DISH) result from a "protective" effect of the pulsating descending left sided thoracic aorta.

Methods: Chest CTs of patients with DISH and right-sided aorta and controls with left-sided aorta were evaluated and compared on each intervertebral space (IS) for the location of the aorta (right, left, center) and the location of the osteophyte relative to the aorta (contralateral, ipsilateral, bilateral).

Results: The study and control cohorts included 31/35 subjects) M/F : 22/9/27/8 median age: 64. Read More

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Identification of ENPP1 Haploinsufficiency in Patients With Diffuse Idiopathic Skeletal Hyperostosis and Early-Onset Osteoporosis.

J Bone Miner Res 2022 06 11;37(6):1125-1135. Epub 2022 Apr 11.

Division of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan.

Homozygous ENPP1 mutations are associated with autosomal recessive hypophosphatemic rickets type 2 (ARHR2), severe ossification of the spinal ligaments, and generalized arterial calcification of infancy type 1. There are a limited number of reports on phenotypes associated with heterozygous ENPP1 mutations. Here, we report a series of three probands and their families with heterozygous and compound heterozygous ENPP1 mutations. Read More

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