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[Alternative Psychoses and Forced Normalization after Seizure Control by Anticonvulsants with Special Consideration of the New Anticonvulsants].

Fortschr Neurol Psychiatr 2019 Feb 20. Epub 2019 Feb 20.

Zentrum für Psychiatrie Südwürttemberg, Klinik für Psychiatrie und Psychotherapie I, Universität Ulm.

In the case of alternative psychosis and forced normalization, the patient alternates between periods of clinically manifest seizures and normal behavior, and other periods of seizure freedom (or significant seizure reduction) accompanied by psychosis or behavioral disturbances. Unlike the clinically defined alternative psychosis, forced normalization is based on EEG findings. In clinical practice and in the literature, both terms are mostly used synonymously, and they also describe the same clinical pictures. Read More

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http://dx.doi.org/10.1055/a-0820-3345DOI Listing
February 2019

[Advance research directives in the context of dementia research: Ethical reflections on the disclosure requirement].

Fortschr Neurol Psychiatr 2019 Feb 20. Epub 2019 Feb 20.

Ruhr-Universität Bochum, Medizinische Fakultät, Institut für medizinische Ethik und Geschichte der Medizin.

In November 2016, the German Federal Diet adopted an amendment to the German Medicinal Products Act (Arzneimittelgesetz), which permits non-therapeutic biomedical research on incompetent adults under a number of strict conditions. One of these conditions is that the potential research participant has declared her wish to participate in biomedical research in a valid research advance directive. Before completing the research advance directive, the potential research participant must be informed about the circumstances of research participation. Read More

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http://dx.doi.org/10.1055/a-0664-7980DOI Listing
February 2019

Lithopedion Causing Intestinal Obstruction in a 71-Year-Old Woman: A Case Report Litopedia causando obstrução intestinal em idosa de 71 anos: relato de caso.

Rev Bras Ginecol Obstet 2019 Feb 20;41(2):129-132. Epub 2019 Feb 20.

Division of Medicine, Fortaleza Health Squadron, Força Aérea Brasileira, Fortaleza, CE, Brazil.

Ectopic pregnancy is the leading cause of pregnancy-related death during the first trimester, and it occurs in 1 to 2% of pregnancies. Over 90% of ectopic pregnancies are located in the fallopian tube. Abdominal pregnancy refers to an ectopic pregnancy that has implanted in the peritoneal cavity, external to the uterine cavity and fallopian tubes. Read More

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http://dx.doi.org/10.1055/s-0038-1676060DOI Listing
February 2019

[Pedicled Flaps in the Reconstruction of Complex Wounds at the Lower Extremity].

Z Orthop Unfall 2019 Feb 20;157(1):95-108. Epub 2019 Feb 20.

The present refresher article highlights the current role of pedicled flaps in the reconstruction of complex wounds at the lower extremity. Due to the increasing standardization and ongoing improvements in microsurgery and in view of the fact that local tissue limitation and elevated rates of wound healing disorders reduced the attraction of pedicled flaps to the lower extremity, free flaps became a serious alternative. However, in consideration of the individual patient demand pedicled flaps to the lower extremity still have their eligibility and can be superior to free flaps in selected cases. Read More

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http://dx.doi.org/10.1055/s-0043-124091DOI Listing
February 2019

[Health Expertise of Seasonal Influenza Vaccination among Midwife Trainees in North Rhine-Westphalia: Results of a Cross-Sectional Study].

Gesundheitswesen 2019 Feb 20. Epub 2019 Feb 20.

Institut für Hausarztmedizin, Medizinische Fakultät der Universität Bonn, Bonn.

Objective: For the first time, the level of knowledge and attitude towards vaccinations in general as well as seasonal influenza vaccination of midwife trainees in Germany was assessed.

Methods: The cross-sectional study was conducted between May and July 2017. The written standardized questionnaire was completed by all midwife-trainees in North Rhine-Westphalia. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0839-4810
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http://dx.doi.org/10.1055/a-0839-4810DOI Listing
February 2019
2 Reads

[Developments in Emergency Care - Analysis of Emergency Cases in In- and Outpatient Care from 2009 To 2015 in Germany].

Gesundheitswesen 2019 Feb 20. Epub 2019 Feb 20.

Fachgebiet Management im Gesundheitswesen, Gesundheitsökonomisches Zentrum Berlin, Technische Universität Berlin, Berlin.

Background: Increasing numbers of emergency cases, different stakeholders involved (physicians' practices vs. hospitals providing ambulatory and inpatient care) and changing patient utilization patterns lead to changes in health care needs. This study aimed at analyzing changes in patient characteristics as well as indications for in- and outpatient emergency care between 2009 and 2015 and their potential reasons. Read More

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http://dx.doi.org/10.1055/a-0820-3904DOI Listing
February 2019

["Crystal" and Pregnancy - The Preliminary Results of a Retrospective Study on the Course of Pregnancy and Delivery of Women Consuming Methamphetamine].

Z Geburtshilfe Neonatol 2019 Feb 20. Epub 2019 Feb 20.

Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Carl Gustav Carus Dresden, Dresden.

Introduction: It can be observed that there is an increase in the methamphetamine (MA) consumption in Saxony (Federal Republic of Germany). There is so far no data available in German speaking countries about the risk of MA consumption in pregnancy or delivery.

Methods: The data from all pregnant women who were examined or delivered at the Clinic for Obstetrics and Gynaecology between 2010-2015 were retrospectively searched for MA consumption. Read More

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http://dx.doi.org/10.1055/a-0831-3642DOI Listing
February 2019

Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes.

Invest Ophthalmol Vis Sci 2019 Feb;60(2):704-711

Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, United States.

Purpose: While VZV DNA and antigen have been detected in acute and chronic VZV keratitis, it is unclear whether productive infection of corneal cells is ongoing or whether residual, noninfectious VZV antigens elicit inflammation. Herein, we examined VZV-infected primary human corneal epithelial cells (HCECs) and keratocytes (HKs) to elucidate the pathogenesis of VZV keratitis.

Methods: HCECs and HKs were mock- or VZV infected. Read More

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http://dx.doi.org/10.1167/iovs.18-25801DOI Listing
February 2019

An artificial habitat facilitates a climate-mediated range expansion into a suboptimal novel ecosystem.

PLoS One 2019 20;14(2):e0211638. Epub 2019 Feb 20.

Department of Biology, Brigham Young University, Provo, UT.

As the geographic ranges of tropical species and ecosystems continue to shift poleward with climate change, it is critical to prediction and management to identify factors that facilitate these expansions. This is especially true for range shifts that involve the decoupling of a shifting species from its historic ecosystem and the colonization of an ecosystem that it has not previously inhabited (i.e. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211638PLOS
February 2019

Long-term history of vehicle collisions on the endangered Nēnē (Branta sandvicensis).

PLoS One 2019 20;14(2):e0210180. Epub 2019 Feb 20.

Pacific Cooperative Studies Unit, Department of Botany, University of Hawai'i at Mānoa, Honolulu, HI, United States of America.

Millions of birds in the United States die annually due to vehicle collisions on roads. Collisions may be of particular interest for species of conservation concern, such as the endangered Hawaiian goose (Nēnē), which is endemic to Hawai'i. Using a nearly 40-year dataset of Nēnē road mortality in and around Hawai'i Volcanoes National Park, we sought to answer the following research questions: 1) has Nēnē mortality changed over time? 2) are there times of the year in which mortality is greatest and does it relate to specific events in the species' lifecycle? 3) does age at mortality differ over time, space, or sex? 4) given that existing mortalities appear to occur only in certain locations, do the number of mortality events differ across these locations; 5) does mortality rate show any density dependence? and, 6) are mortality rates related to numbers of visitors or vehicles? Between 1977 and 2014, a total of 92 Nēnē died from vehicle collisions; while absolute mortality increased over this time, the mortality rate remained the same. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210180PLOS
February 2019

Live or Let Die: T Cell Survival in Cancer Immunotherapy.

Immunity 2019 Feb;50(2):280-282

Laboratory of Experimental Dermatology, Department of Dermatology, Otto-von-Guericke University, Magdeburg, Germany. Electronic address:

Combination immune checkpoint blockade targeting CTLA-4 and PD-1 is thought to reinvigorate exhausted T cells better than monotherapies. In this issue of Immunity, Pai et al. (2019) show that, in the setting of low tumor burden, this combination regimen promotes interferon-γ-dependent T cell hyperactivation and death and thus favors tumor progression. Read More

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http://dx.doi.org/10.1016/j.immuni.2019.01.016DOI Listing
February 2019

Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision.

Sci Rep 2019 Feb 19;9(1):2314. Epub 2019 Feb 19.

Stem Cells and Regenerative Medicine Section, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK.

Irreversible photoreceptor cell death is a major cause of blindness in many retinal dystrophies. A better understanding of the molecular mechanisms underlying the progressive loss of photoreceptor cells remains therefore crucial. Abnormal expression of microRNAs (miRNAs) has been linked with the aetiology of a number of retinal dystrophies. Read More

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http://dx.doi.org/10.1038/s41598-018-38294-9DOI Listing
February 2019

Retrospective cohort analysis of real-life decisions about end-of-life care preferences in a Southeast Asian country.

BMJ Open 2019 Feb 19;9(2):e024662. Epub 2019 Feb 19.

Centre for Population Health Sciences, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.

Objective: To describe the end-of-life care preferences of individuals, and to examine the influence of age and gender on these preferences.

Design, Setting And Participants: A retrospective cohort study was conducted. Participants included all adults (≥21 years old) (n=3380) who had completed a statement of their preferences as part of a national Advance Care Planning (ACP) programme in Singapore. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02466
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http://dx.doi.org/10.1136/bmjopen-2018-024662DOI Listing
February 2019
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Particulate matter emissions of four types of one cigarette brand with and without additives: a laser spectrometric particulate matter analysis of secondhand smoke.

BMJ Open 2019 Jan 15;9(1):e024400. Epub 2019 Jan 15.

Institute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfut am Main, Germany.

Objective: Inhaled particulate matter (PM) in secondhand smoke (SHS) is deleterious for smokers and non-smokers. Different additives in cigarettes might effect the amount of PM. This study aimed to assess the influence of additives on the PM emissions from different cigarette types in SHS. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024400DOI Listing
January 2019

First Report of Endophytic Candida ipomoeae Isolated from Ovules of Upland Cotton in Mississippi.

Plant Dis 2006 Oct;90(10):1362

Crop Genetics and Production Research Unit, USDA-ARS, 141 Experiment Station Rd, Stoneville, MS 38776.

Cotton is grown on approximately 34.5 million ha worldwide to provide fiber, food oil, and animal feed. To our knowledge, this report is the first of Candida ipomoeae on cotton, and this yeast was found on ovules of the most commercially important cotton species in a major cotton-growing region. Read More

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http://dx.doi.org/10.1094/PD-90-1362BDOI Listing
October 2006

First Report of Spring Dead Spot of Zoysiagrass Caused by Ophiosphaerella korrae in the United States.

Plant Dis 2007 Dec;91(12):1684

Department of Plant Pathology, North Carolina State University, Raleigh 27695.

Since 2002, symptoms of an unknown disease have been observed in 'El Toro' zoysiagrass (Zoysia japonica Steud.) in several locations across North Carolina. Symptoms become evident in the spring as the zoysiagrass comes out of winter dormancy. Read More

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http://dx.doi.org/10.1094/PDIS-91-12-1684ADOI Listing
December 2007

Xylella fastidiosa Detected in New Mexico in Chitalpa, a Common Landscape Ornamental Plant.

Plant Dis 2007 Mar;91(3):329

New Mexico State University, Department of Entomology, Plant Pathology, and Weed Science, Las Cruces 88003.

Different strains of Xylella fastidiosa cause a variety of significant disease problems in agricultural and ornamental plants, including Pierce's disease in grapes, oleander leaf scorch, pecan bacterial leaf scorch, and alfalfa dwarf disease. X. fastidiosa has never been reported in New Mexico but is known to exist in surrounding states (California, Arizona, and Texas). Read More

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http://dx.doi.org/10.1094/PDIS-91-3-0329BDOI Listing

Occurrence of Rust Caused by Puccinia carthami on Snow Lotus in China.

Authors:
S Zhao G-L Xie H Li C Li

Plant Dis 2007 Jun;91(6):772

School of Life Science and Technology, Beijing Institute of Technology, 100081, Beijing, China.

Snow lotus (Saussurea involucrata (Kar. & Kir.) Sch. Read More

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http://dx.doi.org/10.1094/PDIS-91-6-0772ADOI Listing

Fate of Astrocytes in The Gerbil Hippocampus After Transient Global Cerebral Ischemia.

Int J Mol Sci 2019 Feb 15;20(4). Epub 2019 Feb 15.

Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.

Neuronal death and reactive gliosis are major features of brain tissue damage following transient global cerebral ischemia (tgCI). This study investigated long-term changes in neuronal death and astrogliosis in the gerbil hippocampus for 180 days after 5 min of tgCI. A massive loss of pyramidal neurons was found in the hippocampal CA1 area (CA1) area between 5 and 30 days after tgCI by Fluoro-Jade B (FJB, a marker for neuronal degeneration) histofluorescence staining, but pyramidal neurons in the CA2/3 area did not die. Read More

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http://dx.doi.org/10.3390/ijms20040845DOI Listing
February 2019

[Follow-Up and Surveillance after Lung Cancer Treatment].

Zentralbl Chir 2019 Feb 19;144(1):106-117. Epub 2019 Feb 19.

The aim of this article is to present the current guideline recommendations for the follow-up and surveillance of lung cancer patients and to outline an evidence-based approach to planing individualised follow-up care. Read More

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http://dx.doi.org/10.1055/s-0043-111766DOI Listing
February 2019

5-Aminosalicilates: Old Habits Die Hard.

Gastroenterology 2019 Feb 16. Epub 2019 Feb 16.

Gastroenterology Division, Hospital Beatriz Ângelo, Loures, Portugal.

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http://dx.doi.org/10.1053/j.gastro.2019.02.019DOI Listing
February 2019

Fit Accuracy of Pressed and Milled Lithium Disilicate Inlays Fabricated From Conventional Impressions or a Laboratory-Based Digital Workflow.

Eur J Prosthodont Restor Dent 2019 Feb 5. Epub 2019 Feb 5.

Lebanese University, Faculty of Dental Medicine.

Purpose: The impact of material on the adaptation of lithium disilicate inlays is poorly documented. This in vitro study aims at comparing the fit accuracy of pressed and milled inlays obtained from conventional impression and laboratory-based computer-aided design and computer-aided manufacturing.

Material And Methods: A typodont molar was prepared for a mesio-occlusal ceramic inlay. Read More

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http://dx.doi.org/10.1922/EJPRD_01828Homsy08DOI Listing
February 2019

Improved Set-Size Labeling Mediates the Effect of a Counting Intervention on Children's Understanding of Cardinality.

Dev Sci 2019 Feb 18:e12819. Epub 2019 Feb 18.

University of Notre Dame.

How does improving children's ability to label set sizes without counting affect the development of understanding of the cardinality principle? It may accelerate development by facilitating subsequent alignment and comparison of the cardinal label for a given set and the last word counted when counting that set (Mix et al., 2012). Alternatively, it may delay development by decreasing the need for a comprehensive abstract principle to understand and label exact numerosities (Piantadosi et al. Read More

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http://dx.doi.org/10.1111/desc.12819DOI Listing
February 2019

Genotyping of circulating cell-free DNA enables non-invasive tumor detection in myxoid liposarcomas.

Int J Cancer 2019 Feb 18. Epub 2019 Feb 18.

Department of Plastic and Hand Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Soft tissue sarcomas (STS) are rare tumors of mesenchymal origin. About 50% of patients with STS experience relapse and more than 30% will die within 10 years after diagnosis. In this study we investigated circulating free DNA (cfDNA) and tumor-specific genetic alterations therein (circulating tumor DNA, ctDNA) as diagnostic biomarkers. Read More

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http://dx.doi.org/10.1002/ijc.32216DOI Listing
February 2019

Frailty predicts mortality in all emergency surgical admissions regardless of age. An observational study.

Age Ageing 2019 Feb 19. Epub 2019 Feb 19.

Ageing Clinical & Experimental Research (ACER) Team, Institute of Applied Health Research, University of Aberdeen, Aberdeen, UK.

Background: frail patients in any age group are more likely to die than those that are not frail. We aimed to evaluate the impact of frailty on clinical mortality, readmission rate and length of stay for emergency surgical patients of all ages.

Methods: a multi-centre prospective cohort study was conducted on adult admissions to acute surgical units. Read More

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http://dx.doi.org/10.1093/ageing/afy217DOI Listing
February 2019

On-chip combined radiotherapy and chemotherapy testing on soft-tissue sarcoma spheroids to study cell death using flow cytometry and clonogenic assay.

Sci Rep 2019 Feb 18;9(1):2214. Epub 2019 Feb 18.

Institut du Cancer de Montréal, Montréal, Qc, Canada.

Radiotherapy (RT) and chemotherapy (CT) are the major therapeutics to treat cancer patients. Conventional in vitro 2D models are insufficient to study the combined effects of RT and CT towards optimized dose selection or drug screening. Soft-tissue sarcomas (STS) are rare cancers with profound social impacts as they affect patients of all ages. Read More

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http://dx.doi.org/10.1038/s41598-019-38666-9DOI Listing
February 2019

Sir Winston Churchill KG: hip fracture in Monte Carlo ('Remember, I want to die in England') on 28 June 1962, femoral vein thrombosis and jaundice in London.

J R Soc Med 2019 Feb 19:141076819830040. Epub 2019 Feb 19.

3 National Hospital for Neurology & Neurosurgery, London, WC1N 3BG UK.

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http://dx.doi.org/10.1177/0141076819830040DOI Listing
February 2019

[Magnetic Resonance Imaging of the Orbital Cavity: Indications and Diagnostic Possibilities].

Klin Monbl Augenheilkd 2019 Feb 18. Epub 2019 Feb 18.

Today, magnetic resonance imaging (MRI) is considered the diagnostic tool of choice for eye and orbital pathologies. In this article, the MR image characteristics of relevant pathologies are illustrated with case-based examples in the context of clinical findings. Vascular pathologies (such as capillary and cavernous hemangioma), inflammatory diseases (such as endocrine orbitopathy), and neoplasms (such as lymphoma, uveal melanoma, retinoblastoma, and ocular/orbital metastasis) are described. Read More

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http://dx.doi.org/10.1055/a-0849-0000DOI Listing
February 2019

[Scleral Buckling].

Authors:
Silvia Bopp

Klin Monbl Augenheilkd 2019 Feb 18. Epub 2019 Feb 18.

Buckling techniques are used for rhegmatogenous (break-induced) retinal detachment. The aim is to achieve a functional closure of the retinal breakwith permanent retinal attachment by scleral indentation and coagulation of retinal holes. The surgery is primarily extraocular. Read More

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http://dx.doi.org/10.1055/a-0849-0069DOI Listing
February 2019

[Pars plana vitrectomy].

Klin Monbl Augenheilkd 2019 Feb 18. Epub 2019 Feb 18.

Pars plana vitrectomy (PPV) allows the treatment of a multitude of vitreoretinal disorders involving the vitreous, the retina or the choroid. There is a multitude of possible surgical sequences: peeling maneuvers, liquid perfluorocarbone, removal of traction and media opacities, retinopexy or destructive photocoagulation, and as ultima ratio, retinotomies and retinectomies. The intravitreal tamponade serves as a substitute in the vitreous cavity, allowing photoreceptors and retinal pigment epithelium (RPE) to reconnect. Read More

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http://dx.doi.org/10.1055/a-0849-0148DOI Listing
February 2019

[A benign tumour of the parotid gland - a rare diagnosis].

Laryngorhinootologie 2019 Feb 18. Epub 2019 Feb 18.

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http://dx.doi.org/10.1055/a-0839-5241DOI Listing
February 2019

[Coincidence of Advance Directive and Organ Donor Consent: What Do The Persons Concerned Want? A Survey of German Elderly Citizens].

Gesundheitswesen 2019 Feb 18. Epub 2019 Feb 18.

Palliative and Supportive Care Service, Lausanne University Hospital, Lausanne, Switzerland.

Aims: In the case of acute brain injury, decision-making uncertainties can arise when both an advance decision to refuse treatment and a prior consent to post-mortem organ donation are present. It is yet unknown how the persons concerned view this potential conflict. The present study aims to investigate how frequent this situation is, whether the persons concerned are aware of the potential conflict and what they would prioritize. Read More

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http://dx.doi.org/10.1055/a-0837-0882DOI Listing
February 2019

Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate cancer.

Asian J Urol 2019 Jan 28;6(1):99-108. Epub 2018 Nov 28.

Department of Oncology, Prostate Cancer Program, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Localized prostate cancer is curable via annihilation of the entire cancer neighborhood by surgery or local radiation. Unfortunately, once metastatic, no available therapy is curative. The vast majority will die despite aggressive systemic combinational androgen-ablation therapies. Read More

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http://dx.doi.org/10.1016/j.ajur.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363604PMC
January 2019

No One Should Die of Melanoma: Time for This Vision to Be Realized?

Dermatol Pract Concept 2019 Jan 31;9(1):1-3. Epub 2019 Jan 31.

Dermatology Unit, University of Campania, Naples, Italy.

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http://dx.doi.org/10.5826/dpc.0901a01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368076PMC
January 2019
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Crystallographic characterization of LuC (2 = 76-90): cluster selection by cage size.

Chem Sci 2019 Jan 30;10(3):829-836. Epub 2018 Oct 30.

State Key Laboratory of Materials Processing and Die & Mould Technology , School of Materials Science and Engineering , Huazhong University of Science and Technology , 1037 Luoyu Road , Wuhan , 430074 , China . Email:

The successful isolation and unambiguous crystallographic assignment of a series of lutetium-containing endohedral metallofullerenes (EMFs), LuC (2 = 76, 78, 80, 84, 86, 88, 90), reveal an unrecognized decisive effect of the cage size on the configuration of the encapsulated clusters. The molecular structures of these compounds are unambiguously assigned as Lu@(2)-C, Lu@(5)-C, Lu@(5)-C, Lu@(7)-C, Lu@(8)-C, Lu@(15)-C, Lu@(26)-C, LuC@(9)-C, LuC@(32)-C and LuC@(35)-C. Specifically, when the cage is relatively small, Lu@C (2 = 76-86) are all dimetallofullerenes (di-EMFs) and a Lu-Lu single bond could be formed between the two lutetium ions inside the cages. Read More

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http://dx.doi.org/10.1039/c8sc03886dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345353PMC
January 2019

Development of feline embryos produced by Piezo-actuated intracytoplasmic sperm injection of elongated spermatids.

J Reprod Dev 2019 Feb 18. Epub 2019 Feb 18.

Department of Advanced Pathobiology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka 598-8531, Japan.

Piezo-actuated intracytoplasmic sperm injection (Piezo-ICSI) is used as an efficient in vitro fertilization method with various animals. With this method, elongated spermatids are collected from testicular tissues and are easier to obtain from animals that unexpectedly die than ejaculate sperm. Additionally, elongated spermatid injection often results in the development of embryos and offspring. Read More

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http://dx.doi.org/10.1262/jrd.2018-119DOI Listing
February 2019

Facile synthesis of novel carbon-dots/hemin nanoplatforms for synergistic photo-thermal and photo-dynamic therapies.

J Inorg Biochem 2019 Feb 1;193:166-172. Epub 2019 Feb 1.

School of Chemistry and Materials Engineering, Fuyang Normal University, Fuyang 236037, PR China. Electronic address:

Due to the traditional therapies of cancer inducing huge pains to patients, the non-invasive photo-guided therapies are attracting massive attentions of researchers. Herein, the intelligent-designed carbon-dots/hemin nanoplatforms (HCDs NPs) were developed, owning high-authority photo-therapy for cancer. The fluorescence resonance energy transfer (FRET) effect enhanced the photo-thermal ability of HCDs NPs, endowing the synthesized nanoplatforms with photo-dynamic property simultaneously. Read More

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http://dx.doi.org/10.1016/j.jinorgbio.2019.01.018DOI Listing
February 2019

Outcomes in different age groups with primary Ewing sarcoma of the spine: a systematic review of the literature.

J Neurosurg Spine 2019 Feb 15:1-10. Epub 2019 Feb 15.

4Division of Neurosurgery, University of Arizona, Tucson; and.

OBJECTIVEEwing sarcoma (ES) is among the most prevalent of bone sarcomas in young people. Less often, it presents as a primary lesion of the spine (5%-15% of patients with ES).METHODSA systematic literature search was performed, querying several scientific databases per PRISMA guidelines. Read More

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http://dx.doi.org/10.3171/2018.10.SPINE18795DOI Listing
February 2019
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Population-based outcomes of men with a single negative prostate biopsy: Importance of continued follow-up among older patients.

Urol Oncol 2019 Feb 13. Epub 2019 Feb 13.

Department of Surgical Oncology, University Health Network, Toronto, ON, Canada; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.

Purpose: To determine in Ontario-based men with a single negative transrectal ultrasound-guided prostate biopsy the long-term rates of prostate cancer-specific mortality, diagnosis, and treatment; number of repeat biopsies; and predictors of prostate cancer diagnosis and mortality.

Materials And Methods: This was a population-based cohort study, using data from linked, validated health administrative databases, of all Ontario-based men with a negative first biopsy between January 1994 and October 2014. Patients were followed from time of first biopsy till death, administrative censoring, or end of study period. Read More

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http://dx.doi.org/10.1016/j.urolonc.2019.01.030DOI Listing
February 2019

A new multi-agent particle swarm algorithm based on birds accents for the 3D indoor deployment problem.

ISA Trans 2019 Feb 4. Epub 2019 Feb 4.

UT2J, CNRS-IRIT (RMESS), University of Toulouse, Toulouse, France. Electronic address:

The 3D indoor deployment of sensor nodes is a complex real world problem, proven to be NP-hard and difficult to resolve using classical methods. In this context, we propose a hybrid approach relying on a novel bird's accent-based many objective particle swarm optimization algorithm (named acMaPSO) to resolve the problem of 3D indoor deployment on the Internet of Things collection networks. The new concept of bird's accent is presented to assess the search ability of particles in their local areas. Read More

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http://dx.doi.org/10.1016/j.isatra.2019.01.026DOI Listing
February 2019

[Dopamine Transporter SPECT with I-123 labelled FP-CIT (DaTSCANTM)].

Nuklearmedizin 2019 Feb 15;58(1):5-16. Epub 2019 Feb 15.

Universitätsklinikum Freiburg, Klinik für Nuklearmedizin.

The aim of the S1 guideline is to assist in establishing the indication and in performing, interpreting and reporting SPECT investigations of the dopamine transporter (DAT) with DaTSCAN. Compared to the preceding version dated from 2007 the current update considers relevant new publications, the guidelines of the European (EANM) and Society of Nuclear Medicine (SNM), and the current version of the S3 guideline of the German Society of Neurology on "Idiopathic Parkinsonsian Syndrome". In addition new technical developments are incorporated. Read More

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http://dx.doi.org/10.1055/a-0807-8137DOI Listing
February 2019

[Propensity Score Methods to Estimate Treatment Effects: An Opportunity for Rehabilitation Service Research].

Rehabilitation (Stuttg) 2019 Feb 15;58(1):50-58. Epub 2019 Feb 15.

Institut für Sozialmedizin und Epidemiologie, Sektion Rehabilitation und Arbeit, Universität zu Lübeck.

The randomized controlled trial is the gold standard to validate the efficacy of an intervention. Randomized treatment assignment in intervention and control group independent of patient characteristics or previous measures of patient care allows one to estimate unbiased treatment effects. Differences in outcomes can be attributed causally to the treatment. Read More

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http://dx.doi.org/10.1055/a-0781-8967DOI Listing
February 2019

[Violence in the Emergency Medicine (Emergency Rescue Service and Emergency Departments) - Current Situation in Germany].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):146-154. Epub 2019 Feb 15.

Background: During the last years healthcare personnel is more often faced with different degrees of violence and aggression while doing their jobs. However, systematic data with respect to offender profiles, reasons, frequency and types of violence in emergency medicine in Germany has not been systematically analyzed.

Aim: The aim of this article is to overview the data of present German studies. Read More

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http://dx.doi.org/10.1055/s-0043-112189DOI Listing
February 2019
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[Coffee, Cigarettes, Chewing Gum - Myths and Facts About Preoperative Fasting].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):142-145. Epub 2019 Feb 15.

Consumption of clear liquids (including coffee and orange juice without pulp) up to 2 hours before the start of anaesthesia is unproblematic. Contrary to the recommendations of the professional societies, the intake of beverages containing milk (up to 50% of the total volume) in small quantities seems to be harmless. Drinks containing alcohol can considerably delay emptying of the stomach. Read More

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http://dx.doi.org/10.1055/s-0043-124943DOI Listing
February 2019

[Focused Abdominal Ultrasound in Emergency, Perioperative and Intensive Care Medicine].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):128-141. Epub 2019 Feb 15.

The rising impact of perioperative sonography is mainly based on mobile high quality ultrasound systems. Relevant bleedings or functional limitations of the abdomen are easy to identify with sonography. The FAST-Concept can be the first access to continue proceedings in ultrasound examination of the abdomen. Read More

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http://dx.doi.org/10.1055/a-0585-5237DOI Listing
February 2019
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[Lung Ultrasound for Anesthesia, Intensive Care and Emergency Medicine].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Feb 15;54(2):108-127. Epub 2019 Feb 15.

Lung ultrasound is an underrated tool in preclinical emergency situations, intensive care units, ORs and emergency rooms. For certain clinical questions, there is a drastically higher sensitivity in comparison to chest X-ray examinations (sensitivity in pneumothorax diagnostics 86 vs. 28%, specificity 97 vs. Read More

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http://dx.doi.org/10.1055/a-0664-5700DOI Listing
February 2019
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Trends in the Stroke Death Rate Among Mississippi Adults, 2000-2016.

Prev Chronic Dis 2019 Feb 14;16:E21. Epub 2019 Feb 14.

Office of Health Data and Research, Mississippi State Department of Health, Jackson, Mississippi.

Introduction: On average, more than 1,700 people in Mississippi die from stroke annually, but data on trends by age, sex, and race in Mississippi are limited. We examined trends in the stroke death rate among adults in Mississippi aged 35 or older by age, sex, and race.

Methods: We used Mississippi Vital Statistics data to calculate age-specific death rates for stroke among people in Mississippi aged 35 or older from 2000 to 2016. Read More

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http://dx.doi.org/10.5888/pcd16.180425DOI Listing
February 2019
1.956 Impact Factor

Can acute stress be fatal? A systematic cross-disciplinary review.

Stress 2019 Feb 15:1-9. Epub 2019 Feb 15.

b Psychiatric Centre Copenhagen, Department O, Rigshospitalet , Copenhagen University Hospital ,  Copenhagen , Denmark.

In this review it is discussed if acute stress can be fatal. The review is based on literature searches on PubMed, PsycINFO as well as Web of Science. Literature concerning the conditions excited delirium syndrome (ExDS), malignant catatonia, takotsubo cardiomyopathy (TCM), and capture myopathy (CM) is reviewed and compared. Read More

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https://www.tandfonline.com/doi/full/10.1080/10253890.2018.1
Publisher Site
http://dx.doi.org/10.1080/10253890.2018.1561847DOI Listing
February 2019
3 Reads