6,442 results match your criteria Diaphragmatic Paralysis

Bilateral Vocal Fold Paralysis After COVID-19 mRNA Vaccination: A Case Report.

J Korean Med Sci 2022 Jun 27;37(25):e201. Epub 2022 Jun 27.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was noted to cause coronavirus disease 2019 (COVID-19) in 2019, there have been many trials to develop vaccines against the virus. Messenger ribonucleic acid (mRNA) vaccine as a type of the vaccine has been developed and commercialized rapidly, but there was not enough time to verify the long-term safety. An 82-year-old female patient was admitted to the emergency room with dyspnea accompanied by stridor three days after the 3rd COVID-19 mRNA vaccination (Comirnaty, Pfizer-BioNTech, USA). Read More

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Diaphragmatic paralysis in a neonate with circumferential skin creases Kunze type.

Mol Genet Genomic Med 2022 Jun 23:e2003. Epub 2022 Jun 23.

Department of Neonatology, Wuhan Children's Hospital of Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.

Background: A range of clinical features have been confirmed with heterozygous mutations in Beta Tubulin (TUBB), including skin creases, facial deformities, abnormal cerebral structures, and intellectual disability, and were defined as Circumferential Skin Creases Kunze type (CSC-KT).

Methods: Clinical information was obtained retrospectively on a neonate hospitalized in the Neonatal Intensive Care Unit, Wuhan Children's Hospital. Genomic DNA was extracted from circulating leukocytes of the proband according to standard procedures. Read More

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Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review.

Exp Ther Med 2022 Jul 23;24(1):462. Epub 2022 May 23.

Department of Pediatrics, Chivasso Hospital, I-10034 Turin, Italy.

Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS-CoV-2 infection. Case reports of novel coronavirus disease 2019 (COVID-19)-associated GBS mainly include adult patients, while only a few pediatric cases have been reported. Read More

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EEG Classification of Normal and Alcoholic by Deep Learning.

Houchi Li Lei Wu

Brain Sci 2022 Jun 14;12(6). Epub 2022 Jun 14.

Hunan Engineering Research Center for Intelligent Decision Making and Big Data on Industrial Development, Hunan University of Science and Technology, Xiangtan 411100, China.

Alcohol dependence is a common mental disease worldwide. Excessive alcohol consumption may lead to alcoholism and many complications. In severe cases, it will lead to inhibition and paralysis of the centers of the respiratory and circulatory systems and even death. Read More

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Outcomes of endoscopic percutaneous suture lateralization for neonatal and infantal bilateral vocal ford paralysis.

Braz J Otorhinolaryngol 2022 Jun 9. Epub 2022 Jun 9.

Children's Hospital of Fudan University, Department of Otolaryngology-Head and Neck Surgery, Shanghai, China.

Objective: Bilateral Vocal Fold Paralysis (BVFP) is a rare but significant resource of respiratory distress in neonates and infants. The objective of this study was to evaluate the efficacy and functional outcomes of Endoscopic Percutaneous Suture Lateralization (EPSL) for the treatment of BVFP in neonates and infants.

Methods: A case series study of nine patients undergoing EPSL for BVFP between January 2019 and June 2021 was conducted. Read More

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Quantitative assessment of progressive laryngeal hemiplegia in a 4-year-old beagle.

Vet Rec Case Rep 2022 Mar 26;10(1). Epub 2021 Nov 26.

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

Progression of unilateral laryngeal paralysis (LP) was quantified in an asymptomatic 4-year-old beagle during spontaneous breathing stimulated with inhaled 10% CO. Laryngeal evaluation was performed sequentially to track progression of LP over an 18-month period. Videos of the larynx during CO-stimulated breathing were obtained under propofol anaesthesia. Read More

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A poor outcome in non-occlusive thrombo-embolic limb ischaemia related to the dislocation of mural thrombus from an abdominal aortic aneurysm.

BMC Cardiovasc Disord 2022 Jun 18;22(1):277. Epub 2022 Jun 18.

Division of NeuroSurgery, Department of Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan.

Background: Acute thrombosis of an abdominal aortic aneurysm with acute limb ischaemia is an unusual complication and is associated with high mortality. Dislocation of the intrasaccular mural thrombus could be one of the mechanisms. For the most part, acute limb ischaemia presents with absent pulses, compatible with the clinical findings, which include pain, paraesthesia, and paralysis. Read More

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Separate evaluation of unilateral lung function using upright/supine CT in a patient with diaphragmatic paralysis.

Radiol Case Rep 2022 Aug 8;17(8):2826-2830. Epub 2022 Jun 8.

Department of Radiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

Background: Unilateral diaphragmatic paralysis is a condition in which the unilateral diaphragm is paralyzed and elevated. Orthopnea due to lung compression by an elevated diaphragm in the supine position is common in patients with unilateral diaphragmatic paralysis. Although its symptom is posture-dependent, the effect of posture on lung function in unilateral diaphragmatic paralysis has not been studied. Read More

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Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases.

Interdiscip Neurosurg 2022 Sep 6;29:101599. Epub 2022 Jun 6.

Department of Neurosurgery, Zagazig University, Zagazig, Egypt.

Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis.

Case Description: Two cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. Read More

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September 2022

Rocuronium versus saline for effective facemask ventilation during anesthesia induction: a double-blinded randomized placebo-controlled trial.

BMC Anesthesiol 2022 Jun 3;22(1):173. Epub 2022 Jun 3.

Department of Anesthesiology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba, 260-8670, Japan.

Background: Mask ventilation progressively improves after loss of consciousness during anesthesia induction possibly due to progression of muscle paralysis. This double-blinded randomized placebo-controlled study aimed to test a hypothesis that muscle paralysis improves mask ventilation during anesthesia induction.

Methods: Forty-four adults patients including moderate to severe obstructive sleep apnea undergoing scheduled surgeries under elective general anesthesia participated in this study. Read More

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Antidotal treatment of botulism in rats by continuous infusion with 3,4-diaminopyridine.

Mol Med 2022 06 3;28(1):61. Epub 2022 Jun 3.

U.S. Army Medical Research Institute of Chemical Defense, Gunpowder, MD, 21010, USA.

Botulinum neurotoxins (BoNTs) are highly potent, select agent toxins that inhibit neurotransmitter release at motor nerve terminals, causing muscle paralysis and death by asphyxiation. Other than post-exposure prophylaxis with antitoxin, the only treatment option for symptomatic botulism is intubation and supportive care until recovery, which can require weeks or longer. In previous studies, we reported the FDA-approved drug 3,4-diaminopyridine (3,4-DAP) reverses early botulism symptoms and prolongs survival in lethally intoxicated mice. Read More

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Poliovirus nonpermissive CD155 knockout cells derived from RD cell line for handling poliovirus potentially infectious materials in virology laboratories.

J Med Virol 2022 Jun 1. Epub 2022 Jun 1.

National Institute of Virology Mumbai Unit, Haffkine Institute Compound, Mumbai, India.

Destruction of all poliovirus containing materials, safe and secure handling of retained polioviruses for vaccine production, and research will be obligatory to eliminate facility-associated risks. Polioviruses and poliovirus potentially infectious materials (PIM) including fecal or respiratory samples requiring containment have been defined in World Health Organization-Global Action Plan (GAP III) documents. Non-polio laboratories culturing viruses from PIM are most affected as cell cultures of human and monkey origin are also poliovirus permissive. Read More

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Cervical Laminoplasty Versus Posterior Laminectomy and Fusion: Trends in Utilization and Evaluation of Complication and Revision Surgery Rates.

J Am Acad Orthop Surg 2022 May 30. Epub 2022 May 30.

From the Rhode Island Hospital, Providence, RI (McDonald, DiSilvestro, Zhang, Kuris, and Daniels), Warren Alpert Medical School/Brown University, Providence, RI (McDonald, Hogan, Alsoof, Kuris, and Daniels), and Massachusetts General Hospital, Harvard Medical School, Boston, MA (Hershman).

Introduction: Cervical laminoplasty (LP) and laminectomy with fusion (LF) are common operations used to treat cervical spondylotic myelopathy. Conflicting data exist regarding which operation provides superior patient outcomes while minimizing the risk of complications. This study evaluates the trends of LP compared with LF over the past decade in patients with cervical myelopathy and examines long-term revision rates and complications between the two procedures. Read More

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Continuously protracted infusion of cisatracurium besilate in patients with ARDS.

Ann Med Surg (Lond) 2022 May 2;77:103718. Epub 2022 May 2.

Department of Critical Care Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, 200233, China.

Background: Acute respiratory distress syndrome (ARDS) is still associated with significant mortality, especially the elderly and those with comorbidities are at highest risk of death. Neuromuscular blocking agents (NMBAs) are used in a large but highly variable proportion of patients with ARDS.

Case Presentation: We describe the case of one critically ill patient with serious ARDS, because of virus pneumonia. Read More

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BDNF and Pro-BDNF in Amyotrophic Lateral Sclerosis: A New Perspective for Biomarkers of Neurodegeneration.

Brain Sci 2022 May 9;12(5). Epub 2022 May 9.

Department of Medical, Surgical and Neurological Sciences, University of Siena, 53100 Siena, Italy.

Amyotrophic Lateral Sclerosis (ALS) is characterized by the progressive degeneration of upper or lower motor neurons, leading to muscle wasting and paralysis, resulting in respiratory failure and death. The precise ALS aetiology is poorly understood, mainly due to clinical and genetic heterogeneity. Thus, the identification of reliable biomarkers of disease could be helpful in clinical practice. Read More

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Case report: Hyperthyroid hypokalemic periodic paralysis.

Ann Med Surg (Lond) 2022 Jun 16;78:103759. Epub 2022 May 16.

Internship at Department of Medicine, Kist Medical College, Kathmandu, Nepal.

Introduction And Importance: HHPP is a rare type of hypokalemic PP that can occur when there is hyperthyroidism.Thyrotoxic periodic paralysis is due to increased influx of potassium into skeletal muscle cells which leads to profound hypokalemia and paralysis. Insulin and Epinephrine are also responsible for stimulating the Na-K-ATPase pumps which are over expressed during hyperthyroid state. Read More

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Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey.

Global Spine J 2022 May 26:21925682221095470. Epub 2022 May 26.

Department of Orthopedic Surgery, Graduate School of Medical Sciences, 38305Kyushu University, Fukuoka, Japan.

Study Design: Retrospective Cohort Study.

Objective: The purpose of this study was to investigate the prognosis of respiratory function in elderly patients with cervical spinal cord injury (SCI) and to identify predictive factors.

Methods: We included 1353 cases of elderly cervical SCI patients collected from 78 institutions in Japan. Read More

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Video-assisted thoracoscopic diaphragmatic plication.

Multimed Man Cardiothorac Surg 2021 Aug 26;2021. Epub 2021 Aug 26.

Thoracic Surgery Department, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

The authors demonstrate a video-assisted thoracoscopic surgical technique for diaphragmatic plication, which is used to treat acquired diaphragmatic paralysis resulting from injury to the phrenic nerve. The objective of the surgical procedure is to return the abdominal contents to their normal position and restore optimal lung expansion by reducing the size of the diaphragmatic surface. Successful diaphragmatic plication improves lung function, reduces dyspnea, and restores quality of life. Read More

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Diaphragm plication using a subcostal approach as an alternative to a thoracotomy.

Carine Pavy

Multimed Man Cardiothorac Surg 2022 Mar 31;2022. Epub 2022 Mar 31.

Diaphragm paralysis is a rare complication in pediatric heart surgery (0.28%-5.6%, depending on the procedure). Read More

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The Mesencephalic Locomotor Region: Beyond Locomotor Control.

Front Neural Circuits 2022 9;16:884785. Epub 2022 May 9.

Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

The mesencephalic locomotor region (MLR) was discovered several decades ago in the cat. It was functionally defined based on the ability of low threshold electrical stimuli within a region comprising the cuneiform and pedunculopontine nucleus to evoke locomotion. Since then, similar regions have been found in diverse vertebrate species, including the lamprey, skate, rodent, pig, monkey, and human. Read More

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Spinal muscular atrophy with respiratory distress type 1 (SMARD1): a rare cause of hypotonia, diaphragmatic weakness, and respiratory failure in infants.

Turk J Pediatr 2022 ;64(2):364-374

Department of Pediatric Neurology, University of Health Sciences, Dr. Behçet Uz Children's Education and Research Hospital, İzmir.

Background: Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a very rare autosomal recessive disorder caused by mutations in the immunoglobulin μ-binding protein-2 (IGHMBP2) gene on chromosome 11q13.2-q13.4. Read More

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Effects of a novel, 3D printed bilateral arytenoid abductor on canine laryngeal airway resistance ex vivo.

BMC Vet Res 2022 May 20;18(1):193. Epub 2022 May 20.

Veterinary Specialists and Emergency Services, Rochester, NY, 14623, USA.

Background: Laryngeal paralysis is a disease process most commonly seen in older, large breed dogs. When both arytenoid cartilages are affected dogs can develop life-threatening respiratory compromise, therefore surgical intervention is recommended. While there are multiple surgical procedures that have been described to treat laryngeal paralysis, there remains a considerable risk for postoperative complications, most commonly aspiration pneumonia. Read More

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[Steroid-Resistant Central Nervous System Sarcoidosis: The Selections of Multi-Agent Combination as the Initial Treatment].

Brain Nerve 2022 May;74(5):455-461

Department of Neurology, Yamaguchi Prefectural Grand Medical Center.

Sarcoidosis is a granulomatous multiorgan disease of unknown etiology that commonly affects the respiratory system, eyes, and skin, and less commonly affects the nervous system. Because of its rarity, a standard treatment for central nervous system (CNS) sarcoidosis has not yet been established. Corticosteroids remain the cornerstone of CNS sarcoidosis treatment. Read More

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Long term outcome of laryngeal mobility disorder and quality of life after pediatric cardiac surgery.

Int J Pediatr Otorhinolaryngol 2022 Jul 13;158:111142. Epub 2022 May 13.

Hospices Civils de Lyon, Service d'ORL Pédiatrique, Hôpital Femme Mère Enfants, Bron Cedex, F-69500, France.

Introduction: Laryngeal mobility disorder after a pediatric heart surgery is common (between 5 and 10% of cases), and has important consequences on swallowing, breathing and speaking. After reviewing the literature, the recovery rate is variable and the postoperative follow-up is often done on a short time frame. The primary objective of the study is to describe the recovery from laryngeal mobility disorder with a follow-up time of at least 5 years. Read More

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Minimally Invasive Diaphragm Plication for Acquired Unilateral Diaphragm Paralysis: A Systematic Review.

Innovations (Phila) 2022 May-Jun;17(3):180-190. Epub 2022 May 12.

Department of Thoracic Medicine and Surgery, Division of Thoracic Surgery, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

Diaphragm paralysis is a relatively uncommon entity that can be both congenital and acquired in nature. While commonly asymptomatic, it can also cause a significant decrease in pulmonary function and reserve, particularly in patients with underlying pulmonary diseases. Our aim was to summarize the current literature regarding the minimally invasive techniques used in the surgical correction of acquired diaphragm paralysis via traditional and robotic minimally invasive approaches. Read More

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An Atypical Presentation of West Nile Virus With Successful Treatment After Plasma Exchange and Intravenous Immunoglobulin.

Cureus 2022 Apr 10;14(4):e24003. Epub 2022 Apr 10.

Interventional Radiology, Louisiana State University Health Sciences Center, Shreveport, USA.

West Nile (WN) disease is a relatively rare arboviral virus. Neuroinvasive cases of WN account for less than 1% of the total cases. The case described had difficult symptomatology and radical presentation, which included ascending paralysis. Read More

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Diaphragmatic fracture vs. phrenic paralysis after debulking surgery.

Rev Esp Anestesiol Reanim (Engl Ed) 2022 04 7;69(4):253-254. Epub 2022 May 7.

Servicio de Anestesiología, Reanimación y Tratamiento del Dolor, Hospital Universitario Quirón Dexeus, Barcelona, Spain.

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Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity.

Microb Genom 2022 05;8(5)

School of Life Sciences, University of Nottingham, Nottingham, UK.

Enterovirus D68 (EV-D68) has recently been identified in biennial epidemics coinciding with diagnoses of non-polio acute flaccid paralysis/myelitis (AFP/AFM). We investigated the prevalence, genetic relatedness and associated clinical features of EV-D68 in 193 EV-positive samples from 193 patients in late 2018, UK. EV-D68 was detected in 83 (58 %) of 143 confirmed EV-positive samples. Read More

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Pharyngolaryngeal semiology and prognostic factors in multiple system atrophy.

Eur Arch Otorhinolaryngol 2022 May 5. Epub 2022 May 5.

Department of ENT in Toulouse, Hospital of Larrey, Toulouse, France.

Introduction: Multiple system atrophy (MSA) is a rare degenerative neurological disorder in adults. It induces parkinsonian and/or cerebellar syndrome associated with dysautonomia. Pharyngolaryngeal symptoms are common. Read More

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