56,452 results match your criteria Diaphragmatic Hernias Acquired


Factors and Growth Trends Associated with the Need for Gastrostomy Tube in Neonates with Congenital Diaphragmatic Hernia.

J Pediatr Gastroenterol Nutr 2021 Jun 10. Epub 2021 Jun 10.

Division of Pediatric Surgery, University of California San Francisco, CA, USA.

Objectives: A third of infants with congenital diaphragmatic hernia (CDH) require a gastrostomy tube (GT) for nutritional support. We compared CDH infants who are GT-dependent to those able to meet their nutritional needs orally, to identify factors associated with requiring a GT and evaluate their long-term growth.

Methods: Patients with CDH repaired at a single institution between 2012-2020 were included. Read More

View Article and Full-Text PDF

PCR-based detection of Toxoplasma gondii from cattle in southern Iran.

Comp Immunol Microbiol Infect Dis 2021 Jun 2;77:101677. Epub 2021 Jun 2.

Jahrom City Veterinary Office, Jahrom, Iran.

Objective: Toxoplasma gondii is a protozoan parasite that is widely prevalent in most warm-blooded vertebrates. Humans mainly become infected by eating raw or undercooked meat. This study was designed to investigate the infection of cattle with T. Read More

View Article and Full-Text PDF

Role of Imaging in Obstetric Interventions: Criteria, Considerations, and Complications.

Radiographics 2021 Jun 11:200163. Epub 2021 Jun 11.

From the Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628 (P.J., V.A.F.); Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Conn (M.V.R.); Department of Radiology, Winthrop University Hospital, Mineola, NY (D.S.K.); and Department of Radiology, University of Washington, Seattle, Wash (M.M.).

US has an established role in the prenatal detection of congenital and developmental disorders. Many pregnant women undergo US at 18-20 weeks of gestation for assessment of fetal anatomy and detection of structural anomalies. With advances in fetoscopy and minimally invasive procedures, in utero fetal interventions can be offered to address some of the detected structural and physiologic fetal abnormalities. Read More

View Article and Full-Text PDF

The lost intrauterine device.

Eur J Cardiothorac Surg 2021 Jun 11. Epub 2021 Jun 11.

Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.

View Article and Full-Text PDF

Involved Site Radiotherapy Extends Time to Premature Menopause in Infra-Diaphragmatic Female Hodgkin Lymphoma Patients - An Analysis of GHSG HD14- and HD17-Patients.

Front Oncol 2021 25;11:658358. Epub 2021 May 25.

Department of Radiation Oncology, CyberKnife and Radiation Therapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Introduction: Consolidation radiotherapy in intermediate stage Hodgkin´s lymphoma (HL) has been the standard of care for many years as involved field radiotherapy (IFRT) after chemotherapy. It included initially involved region(s). Based on randomized studies, radiation volumes could be reduced and involved site radiation therapy (ISRT) became the new standard. Read More

View Article and Full-Text PDF

Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia.

J Perinatol 2021 Jun 10. Epub 2021 Jun 10.

Division of Neonatology, Children's Mercy Kansas City, Kansas City, MO, USA.

Objective: To measure short-term outcomes of neonates with congenital diaphragmatic hernia (CDH) while on Neurally Adjusted Ventilator Assist (NAVA), and to measure the impact of a congenitally abnormal diaphragm on NAVA ventilator indices.

Study Design: First, we conducted a retrospective-cohort analysis of 16 neonates with CDH placed on NAVA over a treatment period of 72 h. Second, we performed a case-control study comparing NAVA level and Edi between neonates with CDH and those without CDH. Read More

View Article and Full-Text PDF

[Application progress of ultrasound monitoring of diaphragm function in clinic].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 May;33(5):638-640

Department of Anesthesiology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.

In recent years, point of care ultrasound (POCUS) has developed rapidly in the fields of anesthesia and critical care. POCUS is widely used in clinic to monitor the function of human tissues and organs such as the heart, lungs, and diaphragm due to its visual, non-invasive, portable, and repeatable characters at the bedside. Diaphragm is an important structure to maintain respiratory function. Read More

View Article and Full-Text PDF

Diaphragm neurostimulation during mechanical ventilation reduces atelectasis and transpulmonary plateau pressure, preserving lung homogeneity and PaO2/FiO2.

J Appl Physiol (1985) 2021 06 10. Epub 2021 Jun 10.

Simon Fraser University, British Columbia, Canada.

Tidal volume delivered by mechanical ventilation to a sedated patient is distributed in a non-physiological pattern, causing atelectasis (underinflation) and overdistension (overinflation). Activation of the diaphragm during mechanical ventilation provides a way to reduce atelectasis and alveolar inhomogeneity, protecting the lungs from ventilator-induced lung injury while also protecting the diaphragm by preventing ventilator-induced diaphragm dysfunction. We studied the hypothesis that diaphragm contractions elicited by transvenous phrenic nerve stimulation, delivered in synchrony with volume-control ventilation, would reduce atelectasis and lung inhomogeneity in a healthy, normal-lung pig model. Read More

View Article and Full-Text PDF

Silent Sigmoid Colon Diverticular Perforation: A Case Report.

Cureus 2021 May 8;13(5):e14900. Epub 2021 May 8.

Internal Medicine, Detroit Medical Center Sinai-Grace Hospital, Detroit, USA.

Colonic perforation is associated with high mortality rates, and it requires prompt diagnosis and intervention to ensure favorable patient outcomes. The condition usually presents with typical peritoneal signs and symptoms, but atypical presentations can be a diagnostic challenge. In this report, we present a case of sigmoid diverticulosis perforation in an elderly patient who had no symptoms after the perforation developed. Read More

View Article and Full-Text PDF

Ultrasound-Guided Phrenic Nerve Block for Lung Nodule Biopsy: Single-Center Initial Experience.

Acad Radiol 2021 Jun 7. Epub 2021 Jun 7.

Department of Radiology, Mayo Clinic Hospital, Phoenix, Arizona, and Biostatistics, Mayo Clinic, Scottsdale, Arizona. Electronic address:

Rationale And Objectives: Biopsy of lung nodules in the lower lung fields can be difficult because of breathing motion. Ipsilateral phrenic nerve block (PNB) before biopsy should make the biopsy safer, easier, and more precisely targeted. We describe the use of ultrasound-guided PNB before lung nodule biopsy, including relevant anatomy and variations, complications, and technique, along with our first 40 cases. Read More

View Article and Full-Text PDF

Enhancement of Transmitting Sensitivity of Piezoelectric Micromachined Ultrasonic Transducers By Electrode Design.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 Jun 9;PP. Epub 2021 Jun 9.

This paper investigates the dependence of transmitting sensitivity on the top electrode design of piezoelectric micromachined ultrasonic transducers (PMUTs). Two typical top electrodes, namely inner electrode (IE) and outer electrode (OE), are designed and fabricated. The measured transmitting velocities of the fabricated PMUTs at resonance under a drive voltage of 5 Vp-p (peak-to-peak) are 15. Read More

View Article and Full-Text PDF

Gastrointestinal perforation secondary to COVID-19: Case reports and literature review.

Medicine (Baltimore) 2021 May;100(19):e25771

Department of Internal Medicine-College of Medicine-Imam Abdulrahman Bin Faisal University -King Fahd Hospital of the University-Khobar-Eastern Province-Saudi Arabia.

Introduction: Corona virus disease-2019 (COVID-19) presents primarily with respiratory symptoms. However, extra respiratory manifestations are being frequently recognized including gastrointestinal involvement. The most common gastrointestinal symptoms are nausea, vomiting, diarrhoea and abdominal pain. Read More

View Article and Full-Text PDF

Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia.

N Engl J Med 2021 Jun 8. Epub 2021 Jun 8.

From the Department of Obstetrics and Gynecology, KU Leuven (J.A.D., F.M.R.) and Academic Department of Development and Regeneration, Biomedical Sciences, University Hospitals KU Leuven, Leuven, Belgium (J.A.D., B.V.C., F.M.R.); King's College Hospital (K.H.N.) and the Institute for Women's Health, University College London Hospital (J.A.D.) - both in London; Hospital Antoine-Béclère, Université Paris-Saclay, Clamart, France (A.B.); Hospital Clinic and Sant Joan de Déu, Barcelona (E.G.); Mount Sinai Hospital, Toronto (G.R.); Hospital Maggiore Policlinico, Milan (N.P.); the National Center for Child Health and Development, Tokyo (H.S.); Children's Memorial Hermann Hospital, Houston (A.J.); the Medical University of Warsaw, Warsaw, Poland (M.W.); and University Hospital Bonn, Bonn, Germany (C.B.).

Background: Observational studies have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the left side, but data from randomized trials are lacking.

Methods: In this open-label trial conducted at centers with experience in FETO and other types of prenatal surgery, we randomly assigned, in a 1:1 ratio, women carrying singleton fetuses with severe isolated congenital diaphragmatic hernia on the left side to FETO at 27 to 29 weeks of gestation or expectant care. Both treatments were followed by standardized postnatal care. Read More

View Article and Full-Text PDF

Randomized Trial of Fetal Surgery for Moderate Left Diaphragmatic Hernia.

N Engl J Med 2021 Jun 8. Epub 2021 Jun 8.

From the Department of Obstetrics and Gynecology, University Hospitals KU Leuven (J.A.D., P.L.J.D.) and Academic Department of Development and Regeneration, Biomedical Sciences, KU Leuven, Leuven, Belgium (J.A.D., B.V.C., P.L.J.D.); Hospital Antoine-Béclère, Université Paris-Saclay, Clamart (A.B.), and Necker-Enfants Malades Hospital, Paris (Y.V.) - both in France; Hospital Clinic and Sant Joan de Déu, Barcelona (E.G.); Institute for Women's Health, University College London Hospital (J.A.D.) and King's College Hospital(K.H.N.) - both in London; the University Hospital Bonn, Bonn, Germany (C.B.); Hospital Maggiore Policlinico, Milan (N.P.), and Bambino Gesù Children's Hospital, Rome (F.M.) - both in Italy; Baylor College of Medicine and Texas Children's Hospital (M.B.) and Children's Memorial Hermann Hospital (A.J.) - all in Houston; Mater Mothers' Hospital, Brisbane, QLD, Australia (G.J.G.); the Medical University of Warsaw, Warsaw, Poland (M.W.); and Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands (P.L.J.D.).

Background: Fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased postnatal survival among infants with severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the left side, but data are lacking to inform its effects in infants with moderate disease.

Methods: In this open-label trial conducted at many centers with experience in FETO and other types of prenatal surgery, we randomly assigned, in a 1:1 ratio, women carrying singleton fetuses with a moderate isolated congenital diaphragmatic hernia on the left side to FETO at 30 to 32 weeks of gestation or expectant care. Both treatments were followed by standardized postnatal care. Read More

View Article and Full-Text PDF

Fetal Tracheal Occlusion for Congenital Diaphragmatic Hernia.

Authors:
F Sessions Cole

N Engl J Med 2021 Jun 8. Epub 2021 Jun 8.

From the Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, and St. Louis Children's Hospital - both in St. Louis.

View Article and Full-Text PDF

Early diagnosis of diaphragm palsy after pediatric cardiac surgery and outcome after diaphragm plication - A single-center experience.

Ann Pediatr Cardiol 2021 Apr-Jun;14(2):178-186. Epub 2021 Feb 16.

Department of Cardiovascular and Thoracic Surgery, U.N. Mehta Institute of Cardiology and Research Center, Ahmedabad, Gujarat, India.

Objective: The aims of our prospective observational study were to evaluate the (1) reliability of clinical signs in the early detection of diaphragm palsy (DP); (2) reliability of ultrasonography using echo machine as a bedside tool for the diagnosis of DP; and (3) does early diaphragm plication result in the improved outcome? We also sought to determine the incidence and predominant risk factors for DP and diaphragm plication at our center.

Materials And Methods: This prospective observational study included patients with suspected DP from January 2015 to December 2018. Patients with suspected DP were initially evaluated by bedside ultrasonography using echo machine and confirmed by fluoroscopy. Read More

View Article and Full-Text PDF
February 2021

Degree of foot process effacement in patients with genetic focal segmental glomerulosclerosis: a single-center analysis and review of the literature.

Sci Rep 2021 Jun 8;11(1):12008. Epub 2021 Jun 8.

Department of Pediatric Nephrology, School of Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Determining the cause of focal segmental glomerulosclerosis (FSGS) has crucial implications for evaluating the risk of posttransplant recurrence. The degree of foot process effacement (FPE) on electron micrographs (EM) of native kidney biopsies can reportedly differentiate primary FSGS from secondary FSGS. However, no systematic evaluation of FPE in genetic FSGS has been performed. Read More

View Article and Full-Text PDF

Evaluation of the effect of high protein supply on diaphragm atrophy in critically ill patients receiving prolonged mechanical ventilation.

Nutr Clin Pract 2021 Jun 8. Epub 2021 Jun 8.

Department of Geriatrics ICU, the First Affiliated Hospital with Nanjing Medical University, Nanjing, People's Republic of China.

Background: Our aim was to evaluate the effect of high protein to the target of 2.0 g/kg/d on diaphragm atrophy and clinical prognosis of patients receiving prolonged mechanical ventilation (MV).

Methods: This prospective, randomized, controlled, single-center study included 41 patients who were treated with ≥7 days' MV. Read More

View Article and Full-Text PDF

Prevalence of carotid web in a French cohort of cryptogenic stroke.

J Neurol Sci 2021 May 28;427:117513. Epub 2021 May 28.

Unité Neurovasculaire, Département de Neurologie, Hôpital Gui de Chauliac, Montpellier, France. Electronic address:

Background And Purpose: Carotid webs (CaW) may be an under-recognized cause of anterior circulation cryptogenic ischemic stroke (ACIS). Prevalence is still unknown in European patients with ACIS.

Objective: To evaluate the prevalence of CaW in ACIS and describe patients with CaW phenotype in a cohort of patients from a French stroke center. Read More

View Article and Full-Text PDF

Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia.

J Matern Fetal Neonatal Med 2021 Jun 6:1-6. Epub 2021 Jun 6.

Texas Children's Fetal Center, Baylor College of Medicine, Houston, TX, USA.

Objective: To study the role of fetal endoscopic tracheal occlusion (FETO) on resolution of pulmonary hypertension (PH) in fetuses with isolated moderate left-sided diaphragmatic hernia (CDH).

Methods: This retrospective study included fetuses with CDH evaluated between February 2004 and July 2017. Using the tracheal occlusion to accelerate lung growth (TOTAL) trial definition, we classified fetuses into moderate left CDH if O/E-LHR (observed/expected-lung head ratio) was 25-34. Read More

View Article and Full-Text PDF

Predictive model for postoperative pleural effusion after hepatectomy.

Ann Gastroenterol Surg 2021 May 17;5(3):373-380. Epub 2020 Dec 17.

Department of Surgery Saiseikai Kumamoto Hospital Kumamoto Japan.

Aim: Severe postoperative pleural effusion (sPOPE) after hepatectomy can lead to respiratory distress and may require thoracic drainage, leading to prolonged hospitalization. Preventive chest tube insertion may be useful for patients at high risk for sPOPE. We aimed to develop a predictive model for sPOPE after hepatectomy and evaluate indications for preventive chest tube insertion using our model. Read More

View Article and Full-Text PDF

A case report of gastric volvulus, a rare cause of acute abdomen.

Radiol Case Rep 2021 Jul 26;16(7):1907-1911. Epub 2021 May 26.

Radiology Department of Hospital Universiti Kebangsaan Malaysia, UKM. Kuala Lumpur, Malaysia.

Gastric volvulus is an uncommon disorder with an unknown incidence, unless it stays in the back of the diagnostician's mind, diagnosis of gastric volvulus, which can have significant morbidity and mortality associated with it, can be easily missed and can present either in the acute or chronic setting with variable symptoms. When it occurs in the acute scenario, patients present with severe epigastric pain and retching without vomiting. Together with inability to pass nasogastric tube, they constitute Borchardt's triad. Read More

View Article and Full-Text PDF

Unusual development of the celiac trunk and its clinical significance.

J Vasc Bras 2021 Mar 15;20:e20200032. Epub 2021 Mar 15.

State University of Medicine and Pharmacy "Nicolae Testemitanu", Department of Human Anatomy, Chişinau, Republic of Moldova.

We describe a case of unusual development of the celiac trunk observed in the cadaver of 1-year old male child. The celiac trunk branched into five vessels: the splenic, common hepatic and left gastric arteries, the left inferior diaphragmatic artery, and a short trunk that branched into the right inferior diaphragmatic artery and right accessory hepatic artery. Additionally, the manner of branching of the vessel was unusual: it was possible to distinguish two branching points that corresponded to its s-shaped trajectory. Read More

View Article and Full-Text PDF

Neuropathological hallmarks of fetal hydrocephalus linked to CCDC88C pathogenic variants.

Acta Neuropathol Commun 2021 Jun 6;9(1):104. Epub 2021 Jun 6.

UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics and Reference Center for Developmental Disorders, Normandy Center for Genomic and Personalized Medicine, Normandie Univ, 76000, Rouen, France.

The prevalence of congenital hydrocephalus has been estimated at 1.1 per 1000 infants when including cases diagnosed before 1 year of age after exclusion of neural tube defects. Classification criteria are based either on CSF dynamics, pathophysiological mechanisms or associated lesions. Read More

View Article and Full-Text PDF

Missed injuries in trauma patients: the value of a diagnostic thoracotomy or thoracoscopy during surgical stabilisation of rib fractures.

Ir J Med Sci 2021 Jun 5. Epub 2021 Jun 5.

Department of Surgery, MST - Medisch Spectrum Twente, Koningsplein 1, 7512 KZ, Enschede, Netherlands.

Purpose: Over the last decade Surgical Stabilisation of Rib Fractures (SSFR) gained popularity in our hospital. With increased numbers, we noted that frequently injuries were missed during primary/secondary survey and radiological imaging that were found during the surgical procedure. With this observation, the research question was formulated: What is the value of diagnostics thoracotomy or thoracoscopy during surgical stabilisation of rib fractures?

Methods: In a single-centre, retrospective study between February 2010 and December 2019, trauma patients who underwent Surgical Stabilisation of Rib Fractures (SSFR) and an inspection thoracotomy were included. Read More

View Article and Full-Text PDF

The Intermittent Abdominal Pressure Ventilator as an alternative modality of noninvasive ventilatory support: a narrative review.

Am J Phys Med Rehabil 2021 May 28. Epub 2021 May 28.

Institute of Respiratory Disease, Department of Basic Medical Science, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", Italy Pulmonary Rehabilitation Unit, Don Carlo Gnocchi Foundation, Milan, Italy Department of Physical Medicine and Rehabilitation, Rutgers University New Jersey Medical School, Newark, USA.

Abstract: Noninvasive ventilation has become the initial treatment for symptomatic ventilatory pump failure (VPF) but when used at ventilatory support settings can be an alternative to tracheostomy mechanical ventilation. The intermittent abdominal pressure ventilator (IAPV), a corset with an internal air sack inflated by a ventilator, allows to increase tidal volumes through the raising of the diaphragm and its consequent passive descent. It has been used for daytime support for over 70 years but its knowledge among clinicians is scarce. Read More

View Article and Full-Text PDF

Exercise training decreases intercostal and transversus abdominis muscle blood flows in heart failure rats during submaximal exercise.

Respir Physiol Neurobiol 2021 Jun 4;292:103710. Epub 2021 Jun 4.

Department of Kinesiology, Kansas State University, Manhattan, KS, United States; Department of Anatomy and Physiology, Kansas State University, Manhattan, KS, United States.

Diaphragm muscle blood flow (BF) and vascular conductance (VC) are elevated with chronic heart failure (HF) during exercise. Exercise training (ExT) elicits beneficial respiratory muscle and pulmonary system adaptations in HF. We hypothesized that diaphragm BF and VC would be lower in HF rats following ExT than their sedentary counterparts (Sed). Read More

View Article and Full-Text PDF

Manual Cervical Traction and Trunk Stabilization Cause Significant Changes in Upper and Lower Esophageal Sphincter: A Randomized Trial.

J Manipulative Physiol Ther 2021 May;44(4):344-351

Department of Rehabilitation and Sports Medicine, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic. Electronic address:

Objectives: Dysfunctions in the lower esophageal sphincter (LES) and the upper esophageal sphincter (UES) levels can occur owing to poor muscle coordination, contraction, or relaxation. Such condition can possibly be addressed by functional rehabilitation. The aim of this study was to measure pressure changes in the UES and LES at rest and during routine rehabilitation techniques, that is, cervical manual traction and trunk stabilization maneuver. Read More

View Article and Full-Text PDF

Intrapulmonary artery Doppler to predict mortality and morbidity in fetuses with mild and moderate left-sided congenital diaphragmatic hernia.

Ultrasound Obstet Gynecol 2021 Jun 5. Epub 2021 Jun 5.

Fetal i+D Fetal Medicine Research Center, BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Deu),, Institut Clínic de Ginecologia, Obstetricia i Neonatologia, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

Objective: In fetuses with left-sided isolated congenital diaphragmatic hernia (LCDH), prenatal detection of severe pulmonary hypoplasia is relevant since fetal therapy can improve survival. Moderate and mild hypoplasia still carry a considerable mortality and morbidity risk, but there has been less interest in the accurate prediction of these. In this study on fetuses with moderate or mild CDH, we aimed to investigate: (1) the correlation between intra-pulmonary-artery Doppler (IPaD) findings and mortality, (2) whether adding these improves prediction of mortality based on lung size and liver herniation; and (3) whether the IPaD correlates with early neonatal morbidity. Read More

View Article and Full-Text PDF

NSAID-induced colonic diaphragm disease.

Clin Res Hepatol Gastroenterol 2021 Jun 2;45(6):101728. Epub 2021 Jun 2.

Insitute of Pathology Saarbrücken-Rastpfuhl, Saarbrücken, Germany. Electronic address:

View Article and Full-Text PDF