Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus.
- Kym J Guelfi,
- Ming Jing Ong,
- Shaofu Li,
- Karen E Wallman,
- Dorota A Doherty,
- Paul A Fournier,
- John P Newnham,
- Jeffrey A Keelan
Metabolism 2017 Aug 24. Epub 2017 Aug 24.
Division of Obstetrics & Gynaecology, School of Medicine, Faculty of Health and Medical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia. Electronic address:
Background: Cytokines produced by adipose and placental tissues (adipokines) have been implicated in the development of gestational diabetes mellitus (GDM). There is, however, limited research regarding the relationship between advancing pregnancy, maternal adipokine profile, insulin resistance and the development of GDM. Furthermore, no studies have investigated these parameters in women with a history of GDM who are at the highest risk of recurrence. Read More