- Raphael M Singh,
- Frank C Howarth,
- Ernest Adeghate,
- Keshore Bidasee,
- Jaipaul Singh,
- Tehreem Waqar
Mol Cell Biochem 2018 Feb 23. Epub 2018 Feb 23.
School of Forensic and Applied Sciences, University of Central Lancashire, Preston, England, PR1 2HE, UK.
There is much evidence that diabetes mellitus (DM)-induced hyperglycemia (HG) is responsible for kidney failure or nephropathy leading to cardiovascular complications. Cellular and molecular mechanism(s) whereby DM can damage the kidney is still not fully understood. This study investigated the effect of streptozotocin (STZ)-induced diabetes (T1DM) on the structure and associated molecular alterations of the isolated rat left kidney following 2 and 4 months of the disorder compared to the respective age-matched controls. Read More