2,936 results match your criteria Desmoid Tumor


Aggressive fibromatosis of the upper arm: an unusual cause of radial nerve paresis.

Acta Neurol Belg 2020 May 25. Epub 2020 May 25.

Department of Radiology, AZ Sint-Maarten Mechelen, Liersesteenweg 435, 2800, Mechelen, Belgium.

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http://dx.doi.org/10.1007/s13760-020-01386-3DOI Listing

The value of the black fiber sign on T1-weighted images for predicting stability of desmoid fibromatosis managed conservatively.

Eur Radiol 2020 May 21. Epub 2020 May 21.

Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.

Objectives: It is challenging to know at the first which patients with desmoid fibromatosis (DF) are better suited to conservative or aggressive treatment. To investigate whether the low signal intensity bundles on T1- or T2-weighted images (WI), termed the "black fiber sign (BFS)," can predict non-progressive behavior in the conservative approach.

Methods: This retrospective study included 59 patients with primary DF managed with wait-and-see approach from 2005 to 2018 and serial MR images were analyzed. Read More

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http://dx.doi.org/10.1007/s00330-020-06953-zDOI Listing

Soft Tissue Tumors of the Abdomen and Retroperitoneum.

Surg Clin North Am 2020 Jun 15;100(3):649-667. Epub 2020 Apr 15.

Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, 550 Peachtree Street, Northeast, 9th Floor, Suite 900, Atlanta, GA 30308, USA. Electronic address:

Soft tissue tumors of the abdomen and retroperitoneum encompass a wide range of benign and malignant neoplasms. Retroperitoneal sarcomas, the most common, are composed of rare malignancies with numerous histiotypes. Surgery remains the cornerstone of treatment and the only curative option for retroperitoneal sarcomas. Read More

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http://dx.doi.org/10.1016/j.suc.2020.02.011DOI Listing

Aggressive pelvic angiomyxoma and its mimics: can imaging be the guiding light?

Br J Radiol 2020 May 21:20200255. Epub 2020 May 21.

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Objective: To evaluate the imaging characteristics of aggressive angiomyxoma (AA) and identify features which would help to differentiate it from similar appearing lesions.

Methods: A retrospective review of departmental records was done and cases where AA was suspected on CT or MRI were included. With histopathology as gold-standard, the cases were grouped into AA or mimics and differentiating features were identified on USG, CT and MRI. Read More

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http://dx.doi.org/10.1259/bjr.20200255DOI Listing
May 2020
1.533 Impact Factor

Rapidly Growing Desmoid-Type Fibromatosis of the Mesentery of the Small Intestine after Distal Gastrectomy for Gastric Cancer.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):197-205. Epub 2020 Apr 21.

Department of Gastrointestinal Surgery, Hokkaido Cancer Center, Sapporo, Japan.

We report the case of a 55-year-old man with a surgical history of distal gastrectomy with Roux-en-Y reconstruction performed 3 years prior to the present episode. During the follow-up, a newly developed, rapidly growing intraabdominal mass was detected in the mesentery of the small intestine. Although the patient had been asymptomatic, surgical resection was planned with the suspicion of malignancy, especially lymph node recurrence of the gastric cancer, owing to its rapid growth. Read More

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http://dx.doi.org/10.1159/000506926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204778PMC

Desmoid tumours: a perfect example for making progress in treatment management through international collaboration.

Authors:
B Kasper

ESMO Open 2019 11;4(6)

Sarcoma Unit, Interdisciplinary Tumor Center Mannheim, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany

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http://dx.doi.org/10.1136/esmoopen-2019-000636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001096PMC
November 2019

[A Case of Pelvic Desmoid-Type Fibromatosis Treated by Radiation and Medication Therapies].

Gan To Kagaku Ryoho 2020 Feb;47(2):337-339

Dept. of Gastrointestinal Surgery, Tokyo Medical and Dental University.

The treatment for desmoid-type fibromatosis involves surgical resection and medication therapy, but the standard treatment has not yet been established. In the West, the usefulness of radiation therapy has been reported. We encountered a patient with desmoid-type fibromatosis in the pelvis who was treated by radiation and medication therapies and achieved a good tumor reduction effect. Read More

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February 2020

[A Surgical Case of Desmoid Tumor in the Transverse Mesocolon with Pancreatic Invasion].

Gan To Kagaku Ryoho 2020 Jan;47(1):71-75

Dept. of Surgery, NTT Medical Center Tokyo.

A 40-year-old man with no previous history of abdominal surgery or noteworthy family history presented to our hospital because of a palpable abdominal mass. Abdominal CT revealed a 9 cm diameter mass in the mesocolon. The differential diagnosis included desmoid tumor, and right hemicolectomy with partial resection of the pancreas head and duodenum was performed. Read More

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January 2020

Certain risk factors for patients with desmoid tumors warrant reconsideration of local therapy strategies.

Cancer 2020 Apr 28. Epub 2020 Apr 28.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: The objective of this study was to evaluate treatment outcomes for patients with desmoid tumors (DTs) receiving local therapy with surgery alone, radiation therapy (RT) alone, or combined modality therapy (RT and surgery).

Methods: This was a cross-sectional cohort study of 412 patients with nonmesenteric DTs who received local therapy at the authors' institution between 1965 and 2018.

Results: The median follow-up time was 95 months (range, 1-509 months). Read More

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http://dx.doi.org/10.1002/cncr.32921DOI Listing

Retroperitoneal fibromatosis presenting as a mesenteric mass: A case report.

Medicine (Baltimore) 2020 Apr;99(17):e18799

Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing.

Rationale: Fibromatoses or desmoid tumors are relatively rare tumors derived from the musculoaponeurotic system. This tumor has no specific clinical symptoms and it is sometimes misdiagnosed as other diseases such as gastrointestinal stromal tumors (GISTs).

Patient Concerns: A 28-year-old man visited Peking Union Medical College for a tangible abdominal mass without abdominal pain or distention. Read More

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http://dx.doi.org/10.1097/MD.0000000000018799DOI Listing

Serotonin Syndrome Developing Immediately after the Initiation of Low-Dose Methadone Therapy: A Case Report.

Case Rep Oncol 2020 Jan-Apr;13(1):281-284. Epub 2020 Mar 24.

Department of Pharmacy, Hokkaido University Hospital, Sapporo, Japan.

We present a case in which serotonin syndrome developed immediately after the initiation of low-dose methadone following an increase in oxycodone dose and the initiation of duloxetine. The symptoms of serotonin syndrome were alleviated and later disappeared upon cessation of methadone alone. The case was a 47-year-old woman with a desmoid tumor. Read More

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http://dx.doi.org/10.1159/000506443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154242PMC

Highly aggressive thoracic desmoid tumors in adolescent siblings with fatal outcomes in an FAP kindred: a need for increased vigilance and intervention in at-risk AYAs.

Fam Cancer 2020 Apr 13. Epub 2020 Apr 13.

Division of Hematology-Oncology, Department of Pediatrics, UT Health San Antonio, San Antonio, TX, USA.

Desmoid tumors are a manifestation of familial adenomatous polyposis (FAP), associated with mutation of the APC gene. Although considered benign tumors, desmoids can be aggressive and cause considerable morbidity. Known risk factors for desmoid tumor growth include location of mutations within the APC gene, family history of desmoid tumors, previous surgery, female gender, and pregnancy. Read More

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http://dx.doi.org/10.1007/s10689-020-00177-2DOI Listing

Desmoid fibromatosis following surgical resection of spinal meningioma.

Radiol Case Rep 2020 Jun 7;15(6):697-701. Epub 2020 Apr 7.

Department of Diagnostic Radiology, Musculoskeletal Imaging Section, University of Texas MD Anderson Cancer Center 1515 Holcombe BLVD, Unit 1475, Houston, TX 77030.

A 42-year-old female patient with a history of cervicothoracic junction meningioma World Health Organization grade I, resected in early 2011, was admitted to the hospital with intractable headache and lower extremity weakness. Magnetic resonance imaging (MRI) showed an epidural mass compressing the spinal cord at the prior surgical site, which was interpreted as recurrent meningioma. Following surgical resection, histopathological analysis revealed desmoid fibromatosis (desmoid tumor). Read More

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http://dx.doi.org/10.1016/j.radcr.2020.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139138PMC

Laparoscopic Ureteral Reimplantation for the Management of Long-segment Ureteral Defect in Gynecologic Surgeries.

J Minim Invasive Gynecol 2020 Apr 8. Epub 2020 Apr 8.

Department of Gynecologic Oncology, Cancer Institute Hospital, Koutouku, Tokyo, Japan (all authors).

Objective: To demonstrate techniques of laparoscopic ureteral reconstruction for long-segment ureteral defects in gynecologic surgeries.

Design: Step-by-step demonstration of a laparoscopic ureteral reimplantation using the Boari flap and ileal interposition.

Setting: Gynecologic diseases often involve the ureter; hence, knowledge of ureteral reconstruction techniques is imperative in gynecologic surgeries. Read More

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http://dx.doi.org/10.1016/j.jmig.2020.03.012DOI Listing

Complex Case of Aggressive Intra-abdominal Desmoid-type Fibromatosis Status Post Cholecystectomy.

Cureus 2020 Mar 6;12(3):e7193. Epub 2020 Mar 6.

Radiology, University of Mississippi Medical Center, Jackson, USA.

Desmoid-type fibromatosis (DF), also known as desmoid tumor, is an extremely rare, benign, mesenchymal fibrous tumor with no potential for metastasis. It can arise from any part of the body, most commonly extra-abdominally. Intra-abdominal DF can present sporadically, in sites of previous trauma, surgical scars and irradiation, or in association with familial adenomatous polyposis and Gardner syndrome. Read More

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http://dx.doi.org/10.7759/cureus.7193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137654PMC

Case of medullary thyroid carcinoma with desmoid-type fibromatosis.

Pathol Int 2020 Jun 5;70(6):364-369. Epub 2020 Apr 5.

Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

A 36-year-old man was admitted to hospital for a right thyroid nodule incidentally discovered on a chest computed tomography scan for a rib fracture. He had no history of radiation to the head and neck, no known family history of endocrine disease, and no medical or surgical history. A 17 × 10 mm, well-demarcated, multinodular, whitish nodule with neither necrosis nor hemorrhage was found in the right thyroid. Read More

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http://dx.doi.org/10.1111/pin.12926DOI Listing

[Complex morphological (cytological, histological) diagnostics of desmoid fibroma associated with a breast implant (case report from practice).]

Klin Lab Diagn 2020 ;65(4):228-230

P. Hertsen's Moscow Oncology Research Institute - branch of the National Medical Research Centre оf Radiology of the Ministry of Public Health of Russian Federation.

A rare clinical observation of desmoid fibroma associated with a breast implant is presented. When making a morphological (cytological, histological) diagnosis at the light-optical level before surgery, a differential morphological diagnosis was performed between cicatricial changes, the stromal component of the phyloid tumor and desmoid fibroma. Only immunohistochemistry allowed us to establish a diagnosis of desmoid fibroma, since tumor cells expressed diffusely SMA, focally desmin, and most importantly, ß-catenin expression was observed in some cells. Read More

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http://dx.doi.org/10.18821/0869-2084-2020-65-4-228-230DOI Listing
January 2020

Minimally invasive diagnostic and therapeutic surgery for an intra-abdominal desmoid tumor: A case report.

Gynecol Oncol Rep 2020 May 12;32:100560. Epub 2020 Mar 12.

Department of Gynecologic Oncology, Cancer Institute Hospital, 3-8-31 Ariake, Koutouku, Tokyo 135-8550, Japan.

•Intra-abdominal desmoid tumor is rare with no particular imaging features, so preoperative diagnosis is quite difficult.•R0 resection is essential for treatment but often requires extensive surgical trauma, which can be a risk for recurrence.•A laparoscopic approach for this tumor was effective, with the resulting diagnosis and resection being less traumatic. Read More

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http://dx.doi.org/10.1016/j.gore.2020.100560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090365PMC

Desmoid tumor mimics local recurrence of extremity sarcoma on MRI.

J Surg Oncol 2020 Jun 24;121(8):1259-1265. Epub 2020 Mar 24.

Division of Orthopaedic Oncology, Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background And Objectives: The development of desmoid fibromatosis after tumor resection may mimic local recurrence. To our knowledge, this phenomenon has not been reported after extremity sarcoma resection. We report four cases of desmoid-type fibromatosis ("desmoid tumors") mimicking local recurrence after extremity sarcoma resection. Read More

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http://dx.doi.org/10.1002/jso.25906DOI Listing

Desmoid-Type Fibromatosis-Clinical Study of an Uncommon Disease.

Indian J Surg Oncol 2020 Mar 4;11(1):71-74. Epub 2019 Nov 4.

3Department of Radiology, Government Medical College Kozhikode, Kozhikode, 673008 India.

Desmoid-type fibromatosis is an uncommon disease which mimics sarcoma but is more locally aggressive but with less metastatic potential than sarcoma. Diagnosis is difficult and treatment protocols have changed to include more non-surgical options as compared with sarcoma. This is a retrospective study of the clinical presentation, imaging findings, treatment given, and outcomes of pathologically proven desmoid-type fibromatosis patients who presented to government medical college Kozhikode. Read More

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http://dx.doi.org/10.1007/s13193-019-00985-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064704PMC

[Desmoid type fibromatosis, from radical excision to molecular extirpation].

Bull Cancer 2020 Mar;107(3):344-345

Institut Curie, PSL university, SIREDO Oncology Center (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), 26, rue d'Ulm, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2020.02.006DOI Listing
March 2020
0.635 Impact Factor

Functional analysis of young patients with desmoid-type fibromatosis: Initial surveillance does not jeopardize long term quality of life.

Eur J Surg Oncol 2020 Feb 29. Epub 2020 Feb 29.

Institut Curie, SIREDO Oncology Center Care- Innovation and Research for Children and AYA with Cancer- PSL Research University, Paris, France.

Background: With recent conservative strategies, prognosis of patients with desmoid-type fibromatosis (DTF) is about function preservation. We analyzed the long-term quality of life (QoL) of pediatric patients with DTF.

Methods: All French young patients (<21years) treated between 2005 and 2016 for a DTF in the EpSSG NRSTS-05 study were analyzed. Read More

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http://dx.doi.org/10.1016/j.ejso.2020.02.028DOI Listing
February 2020

Primary mesenteric fibromatosis: A single Center experience.

Ann Ital Chir 2020 Mar 3;9. Epub 2020 Mar 3.

Aim: Primary mesenteric fibromatosis is a rare, locally invasive, non-metastasizing type of intra-abdominal fibromatoses with a very high rate of recurrence. In this study, we aimed to present our surgical approach, tumor characteristics, clinical presentation and long-term follow-up results in cases of primary mesenteric fibromatosis.

Material And Metods: The data collected from 11 patients who underwent surgery due to primary mesenteric fibromatosis in our clinic between 2010 and 2019 were analyzed retrospectively. Read More

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[A Case of Omental Desmoid Tumor after a Small Bowel Resection for Gastrointestinal Stromal Tumor].

Gan To Kagaku Ryoho 2019 Dec;46(13):2488-2490

Dept. of Surgery, Osaka General Hospital of West Japan Railway Company.

An intra-abdominaldesmoid tumor, especially omentaldesmoid tumor, is rare. Here, we report a case of omentaldesmoid tumor after a smallbowelresection for gastrointestinalstromaltumor (GIST). A 73-year-old man underwent a partial resection of smallbowelfor GIST. Read More

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December 2019

Resection of a huge intrathoracic malignant peripheral nerve sheath tumor.

Ann Thorac Surg 2020 Mar 2. Epub 2020 Mar 2.

Department of Cardiothoracic Surgery, Faculty of Medical Science, Lebanese University, Beirut, Lebanon; Department of Cardiothoracic Surgery, Lebanese Geitaoui University Hospital, Beirut, Lebanon;. Electronic address:

Malignant peripheral nerve sheath tumors (MPNST), also known as malignant schwannoma, are rare soft tissue sarcomas [1]. They commonly invade axial sites and rarely do they occur in the thorax [2]. Herein, we present the case of an enormous metastatic multilobulated intrathoracic MPNST that was first misdiagnosed as desmoid fibromatosis and successfully resected for palliative purpose. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.01.046DOI Listing

Combination therapy with sorafenib and celecoxib for pediatric patients with desmoid tumor.

Pediatr Hematol Oncol 2020 Mar 4:1-5. Epub 2020 Mar 4.

Department of Pediatrics, Division of Pediatric Hematology-Oncology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1080/08880018.2020.1735591DOI Listing

Desmoid-type fibromatosis arising from thoracotomy incision.

Clin Case Rep 2020 Feb 29;8(2):389-390. Epub 2019 Dec 29.

Departments of Thoracic Surgery Kanagawa Cancer Center Yokohama Japan.

Desmoid-type fibromatosis following thoracotomy is rare and has been previously reported only in <20 cases; however, it might mimic chest wall recurrence of previous cancer and needs differential diagnosis. When the tumor location corresponded to the thoracotomy incision, we should consider desmoid-type fibromatosis as a differential diagnosis. Read More

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http://dx.doi.org/10.1002/ccr3.2634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044401PMC
February 2020

Fibromatosis-like metaplastic carcinoma: a case report and review of the literature.

Diagn Pathol 2020 Mar 3;15(1):20. Epub 2020 Mar 3.

Department of Pathology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Background: We report an unusual case of low-grade fibromatosis-like metaplastic carcinoma (LG-FLMC) of the breast. This exceedingly rare epithelial breast malignancy has been reported only 68 times in the past 20 years, and is classified as a subtype of metaplastic breast carcinoma (MBC). It is a locally aggressive tumor with a low potential for lymph node and distant metastases, but with a tendency to recur after excision. Read More

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http://dx.doi.org/10.1186/s13000-020-00943-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053053PMC

Factors Associated with Disease Stabilization of Desmoid-Type Fibromatosis.

Clin Orthop Surg 2020 Mar 13;12(1):113-119. Epub 2020 Feb 13.

Musculoskeletal Tumor Center, Seoul National University Cancer Hospital, Seoul, Korea.

Background: Spontaneous disease stabilization of desmoid-type fibromatosis (DF) has been demonstrated in many reports, and the watchful waiting approach without any frontline treatment is becoming popular as an initial management strategy. In this study, we aimed to assess the disease stabilization rate and identify predictive factors for disease stabilization of DF in patients with conservative treatment.

Methods: We reviewed 76 patients with sporadic extra-abdominal DF who were managed with frontline conservative treatment in our institute. Read More

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http://dx.doi.org/10.4055/cios.2020.12.1.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031434PMC

Usefulness of surgical treatment for asymptomatic patients with extra-peritoneal desmoid-type fibromatosis: a systematic review and meta-analysis.

Jpn J Clin Oncol 2020 May;50(5):574-580

Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya, Japan.

Objective: The purpose of this systematic review is to assess and compare the efficacy of surgical treatment for patients with asymptomatic extra-peritoneal desmoid-type fibromatosis to the wait-and-see policy by evaluating (1) the exacerbation rate (exacerbation; recurrence after surgery or progressive disease following non-surgical treatment) and (2) treatment-associated complications in extra-peritoneal desmoid-type fibromatosis.

Methods: We evaluated documents published between 1 January 1990 and 31 August 2017. The risk of bias in the selected literature was analyzed using the Cochrane Collaboration Risk of Bias Tool. Read More

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http://dx.doi.org/10.1093/jjco/hyaa009DOI Listing

Novel pathogenic alterations in pediatric and adult desmoid-type fibromatosis - A systematic analysis of 204 cases.

Sci Rep 2020 Feb 25;10(1):3368. Epub 2020 Feb 25.

Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Münster, Germany.

Desmoid-type fibromatosis (DTF, aggressive fibromatosis) is a non-metastasizing mesenchymal neoplasm of deep soft tissue with a tendency towards local recurrence. Genetic alterations affecting canonical Wnt/β-catenin signaling are reported in the majority of DTF. While most sporadic DTF harbor somatic mutations in CTNNB1, germline mutations in adenomatous polyposis coli (APC) are known to occur in hereditary DTF types (FAP, Gardner-Syndrome). Read More

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http://dx.doi.org/10.1038/s41598-020-60237-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042250PMC
February 2020

An evidence-based guideline on the application of molecular testing in the diagnosis, prediction of prognosis, and selection of therapy in non-GIST soft tissue sarcomas.

Cancer Treat Rev 2020 Apr 14;85:101987. Epub 2020 Feb 14.

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address:

Aims: To make recommendations on the indications for molecular testing regarding the diagnosis, prediction of prognosis, and treatment selection in adult patients with s oft tissue sarcomas (STS) excluding gastrointestinal stromal tumour.

Materials And Methods: This guideline was developed by the Cancer Care Ontario's Program in Evidence-Based Care (PEBC) and the Sarcoma Disease Site Group (DSG). The medline, embase, and Cochrane Library databases, main guideline websites, abstracts of relevant annual meetings, and PROSPERO databases were searched (January 2005 to October 2016). Read More

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http://dx.doi.org/10.1016/j.ctrv.2020.101987DOI Listing

Clinical Characteristics and Treatment of Intra-abdominal Aggressive Fibromatosis: A Retrospective Study of 16 Patients.

Front Med (Lausanne) 2020 31;7. Epub 2020 Jan 31.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

This study aimed to investigate the clinical characteristics and treatment methods for intra-abdominal aggressive fibromatosis. We reviewed the clinical data from 16 patients who were diagnosed with intra-abdominal aggressive fibromatosis and were admitted to Peking Union Medical College Hospital between March 1983 and September 2018. Among the 16 patients, 11 patients presented with a hard smooth abdominal mass with clear borders and a diameter of 4. Read More

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http://dx.doi.org/10.3389/fmed.2020.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006042PMC
January 2020

Desmoid tumor presenting 2 years after elective Roux-en-Y gastric bypass: a case report and review of the literature.

J Surg Case Rep 2020 Feb 7;2020(2):rjz379. Epub 2020 Feb 7.

Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.

Desmoid tumors are rare malignancies derived from myofibroblasts, which can cause significant morbidity due to life-threatening invasion of local structures. Risk factors include familial adenomatous polyposis, antecedent surgical trauma and estrogen exposure. We described a previously healthy 27-year-old female in whom a desmoid tumor developed 2 years after a Roux-en-Y gastric bypass was performed for the treatment of obesity. Read More

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http://dx.doi.org/10.1093/jscr/rjz379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006523PMC
February 2020

Desmoid tumour: rare presentation following neonatal lumbar puncture.

Arch Dis Child Fetal Neonatal Ed 2020 May 6;105(3):298. Epub 2020 Feb 6.

Liverpool Centre for Genomic Medicine, Liverpool Womens NHS Foundation Trust, Liverpool, UK

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http://dx.doi.org/10.1136/archdischild-2018-316210DOI Listing

A case of intrathoracic desmoid tumor with pulmonary disease.

Respir Med Case Rep 2020 20;29:101001. Epub 2020 Jan 20.

Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.

A 68-year-old man who was on treatment for pulmonary complex complained a worsening of sputum. Although he archived negative sputum culture two months ago, sputum culture tests revealed the newly isolation of repeatedly. Chest computed tomography showed newly-appeared extra-pulmonary mass lesion in contact with a cyst at the bottom of his right lung. Read More

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http://dx.doi.org/10.1016/j.rmcr.2020.101001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992532PMC
January 2020

Desmoid tumor at the gastrointestinal anastomosis after a one-anastomosis gastric bypass (mini-gastric bypass): a case report.

J Surg Case Rep 2020 Jan 30;2020(1):rjz411. Epub 2020 Jan 30.

General Surgery Department, Security Forces Hospital Program, Riyadh 11481, Saudi Arabia.

Desmoid tumors of the small bowel wall are rare tumors of the gastrointestinal tract. The signs and symptoms ranging from non-specific to severe abdominal pain to the sensation of a mass and abdominal fullness. We present the case of a 48-year-old man who presented 3 years post-one-anastomosis gastric bypass (mini-gastric bypass) with vague abdominal pain and early satiety of one-month duration. Read More

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http://dx.doi.org/10.1093/jscr/rjz411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990101PMC
January 2020

Mesenteric infiltrative desmoid tumor bordering the pancreas and mimicking liposarcoma.

Clin Res Hepatol Gastroenterol 2020 Jan 31. Epub 2020 Jan 31.

Department of Hospital Pathology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 271, Cheonboro, 11765 Uijeongbu, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2020.01.005DOI Listing
January 2020

Laparoscopic spleen-preserving distal pancreatectomy for a solid-cystic intraabdominal desmoid tumor at a gastro-pancreatic lesion: a case report.

BMC Surg 2020 Feb 3;20(1):24. Epub 2020 Feb 3.

Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.

Background: We report a case of an intraabdominal desmoid tumor that occurred at a gastro-pancreatic lesion with spontaneous cystic features, and present the successful laparoscopic resection of the tumor.

Case Presentation: A 20-mm retroperitoneal cystic mass with a solid component was found adjacent to the stomach and pancreatic body in a 52-year-old woman with no history of familial adenomatous polyposis. Laparoscopic spleen-preserving distal pancreatectomy with wedge resection of the stomach was performed, and complete resection was achieved without intraoperative and postoperative complications. Read More

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http://dx.doi.org/10.1186/s12893-020-0691-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998096PMC
February 2020

[Magnetic resonance imaging of desmoid-type fibromatosis: Current evaluation criteria].

Bull Cancer 2020 Mar 31;107(3):359-363. Epub 2020 Jan 31.

Centre Oscar Lambret, département d'imagerie, 3, rue Fréderic-Combemale, 59000 Lille cedex, France.

The management of desmoid-type fibromatosis has considerably evolved these last years, toward first-line active surveillance then systemic or local symptomatic treatment in case of aggressive tumor. Magnetic resonance imaging is the modality of choice in each of these treatment settings. It needs multiparametric approach taking into account mainly the tumor size, and T2-weighted signal that is correlated with histological composition and clinical behavior. Read More

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http://dx.doi.org/10.1016/j.bulcan.2019.11.009DOI Listing

The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients.

Authors:

Eur J Cancer 2020 Mar 28;127:96-107. Epub 2020 Jan 28.

Desmoid tumor (DT; other synonymously used terms: Desmoid-type fibromatosis, aggressive fibromatosis) is a rare and locally aggressive monoclonal, fibroblastic proliferation characterised by a variable and often unpredictable clinical course. Previously surgery was the standard primary treatment modality; however, in recent years a paradigm shift towards a more conservative management has been introduced and an effort to harmonise the strategy amongst clinicians has been made. We present herein an evidence-based, joint global consensus guideline approach to the management of this disease focussing on: molecular genetics, indications for an active treatment, and available systemic therapeutic options. Read More

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http://dx.doi.org/10.1016/j.ejca.2019.11.013DOI Listing

[Imaging of extraabdominal aggressive fibromatosis].

Rofo 2020 Jan 28. Epub 2020 Jan 28.

University Hospital Ulm, Department of Radiology, Germany.

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http://dx.doi.org/10.1055/a-1085-9585DOI Listing
January 2020

[Resection of soft tissue tumours : Pitfalls, typical complications and prevention strategies].

Orthopade 2020 Feb;49(2):98-103

Schwerpunkt Tumororthopädie, Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland.

Benign soft tissue lesions are 300 times as common as soft tissue sarcomas; hence, the likelihood of confusion is high. Lesions that are larger than 5 cm, deep, show infiltrative growth, or recur despite benign histology are suspicious for soft tissue sarcoma. The biopsy incision must be carefully chosen; in large lipomas, atypical lipomatous tumor should be considered in the differential diagnosis. Read More

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http://dx.doi.org/10.1007/s00132-020-03876-xDOI Listing
February 2020

Management Outcomes Of Extra Abdominal Fibromatosis Among Adult Patients Treated At A Tertiary Care Hospital.

J Ayub Med Coll Abbottabad 2019 Oct-Dec;31(Suppl 1)(4):S660-S664

Jinnah Post-graduate Medical College, Karachi, Pakistan.

Background: Aggressive fibromatosis or desmoid fibromatosis is a soft tissue neoplasm which is non-metastatic in nature. Among all soft tissue tumours, it comprises of 3% cases and is more common in females as compared to males. Objective of our study was to evaluate the treatment outcomes of extra abdominal fibromatosis in patients who were treated in our setup and determine the recurrence patterns. Read More

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Practical approach to diagnosis of bland-looking spindle cell lesions of the breast.

Pathologica 2019 Dec;111(4):344-360

Department of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Azienda Ospedaliero-Universitaria "Policlinico Vittorio Emanuele", Anatomic Pathology, School of Medicine, University of Catania, Italy.

The diagnosis of bland-looking spindle cell lesions of the breast is often challenging because there is a close morphological and immunohistochemical overlap among the different entities. The present review will discuss reactive spindle cell nodule/exuberant scar, nodular fasciitis, inflammatory pseudotumor, myofibroblastoma (classic type), lipomatous myofibroblastoma, palisaded myofibroblastoma, benign fibroblastic spindle cell tumor, spindle cell lipoma, fibroma, leiomyoma, solitary fibrous tumor, myxoma, schwannoma/neurofibroma, desmoid-type fibromatosis, dermatofibrosarcoma protuberans, low-grade fibromatosis-like spindle cell carcinoma, inflammatory myofibroblastic tumor and low-grade myofibroblastic sarcoma arising in the breast parenchyma. The pathologist should be aware of each single lesion to achieve a correct diagnosis to ensure patient a correct prognostic information and therapy. Read More

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http://dx.doi.org/10.32074/1591-951X-31-19DOI Listing
December 2019

[Biology and signaling pathways involved in the oncogenesis of desmoid tumors].

Bull Cancer 2020 Mar 16;107(3):346-351. Epub 2020 Jan 16.

Institut Claudius Régaud, Cancer Research Center in Toulouse (CRCT), IUCT-oncopole, Inserm U1037, 31000, Toulouse, France.

Desmoid tumors (TDs) are derived from mesenchymal stem cells and their pathogenesis is strongly linked to the Wingless/Wnt cascade where the deregulation of β-catenin plays a major role. A mutation of the CTNNB1 encoding β-catenin is found in the majority of sporadic TD cases and constitutional mutations of APC have been described in heritable forms in patients with familial adenomatous polyposis (FAP). Estrogens could also play a role in pathogenesis and this is the basis for the use of hormone therapy. Read More

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http://dx.doi.org/10.1016/j.bulcan.2019.12.003DOI Listing

Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.

Head Neck Pathol 2020 Mar 16;14(1):43-58. Epub 2020 Jan 16.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

Fibroblastic and myofibroblastic neoplasms of the head and neck encompass a group of rare tumor types with often overlapping clinicopathologic features that range in biologic potential from benign to overtly malignant. Even neoplasms with no metastatic potential may provide significant therapeutic challenges in this region due to the unique anatomy of the head and neck. This review will cover the following entities, highlighting important clinical aspects of each neoplasm and then focusing on their characteristic histomorphology, immunophenotype, and molecular alterations: nodular and cranial fasciitis, fibrous hamartoma of infancy, nasopharyngeal angiofibroma, nuchal-type and Gardner fibromas, desmoid fibromatosis, dermatofibrosarcoma protuberans and giant cell fibroblastoma, solitary fibrous tumor, inflammatory myofibroblastic tumor, low-grade myofibroblastic sarcoma, infantile fibrosarcoma, low-grade fibromyxoid sarcoma, and sclerosing epithelioid fibrosarcoma. Read More

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http://dx.doi.org/10.1007/s12105-019-01104-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021862PMC