2,752 results match your criteria Desmoid Tumor


[Two Cases of Resectable Intra-Abdominal Desmoid Tumor after Laparoscopic Gastrectomy for Gastric Cancer].

Gan To Kagaku Ryoho 2019 Jan;46(1):118-120

Dept. of Gastroenterological Surgery, Sendai Kousei Hospital.

Case 1: A 52-year-old man underwent laparoscopic total gastrectomy for gastric cancer. After 2 years, a follow-up computed tomography(CT)scan showed a large, solid 10 cm-sized mass in his left upper abdomen. Under the diagnosis of a suspected mesenchymal tumor, a tumor resection with a partial resection of the upper jejunum and transverse colon was performed. Read More

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January 2019

Rapidly growing breast desmoid tumor with intra-thoracic involvement after reconstructive surgery for breast cancer.

Breast J 2019 Feb 12. Epub 2019 Feb 12.

Department of Surgical Oncology, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.

Desmoid tumors are very rare soft tissue neoplasia that are slow growing and locally aggressive. They grow anywhere in the body and are rarely develop in the breast . Histopathologic examination confirms diagnosis. Read More

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http://doi.wiley.com/10.1111/tbj.13212
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http://dx.doi.org/10.1111/tbj.13212DOI Listing
February 2019
1 Read

Estrogen receptor beta expression correlates with proliferation in desmoid tumors.

J Surg Oncol 2019 Feb 11. Epub 2019 Feb 11.

Department of Oncology, Comprehensive Cancer Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background And Objectives: Estrogen receptor signaling and cyclin D1 have a major role in tumor cell proliferation in breast cancer. Desmoid tumors are rare neoplasms that may respond to endocrine treatment. The present study aimed to investigate the expression levels and the clinical relevance of estrogen receptor beta (ERβ) and cyclin D1 in desmoid tumors. Read More

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http://dx.doi.org/10.1002/jso.25407DOI Listing
February 2019

Bifocal germinoma in a patient with 16p11.2 microdeletion syndrome.

Endocrinol Diabetes Metab Case Rep 2019 Feb 7;2019. Epub 2019 Feb 7.

Department of Endocrinology, Diabetes and Metabolism.

Intracranial germinomas are rare tumors affecting mostly patients at young age. Therefore, molecular data on its etiopathogenesis are scarce. We present a clinical case of a male patient of 25 years with an intracranial germinoma and a 16p11. Read More

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http://dx.doi.org/10.1530/EDM-18-0149DOI Listing
February 2019
7 Reads

A Rare Case of Extra-abdominal Desmoid-type Fibromatosis Arising from the Popliteal Fossa.

Cureus 2018 Nov 28;10(11):e3651. Epub 2018 Nov 28.

Orthopaedics, All India Institute of Medical Sciences, Bhubaneswar, IND.

Desmoids are rare soft-tissue tumors of the abdominal wall that may sporadically occur extra-abdominally. It manifests as clonal fibroblastic proliferation with an infiltrative tendency and capacity to recur without metastasizing. An adolescent male presented with a gradually increasing globular, non-tender, firm, non-pulsatile swelling (8 × 5 × 3 cm) in the left popliteal fossa that had been present for five months. Read More

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https://www.cureus.com/articles/16190-a-rare-case-of-extra-a
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http://dx.doi.org/10.7759/cureus.3651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351114PMC
November 2018
1 Read

Refractory and metastatic infantile fibrosarcoma harboring fusion shows complete and durable response to crizotinib.

Cold Spring Harb Mol Case Stud 2019 Feb 1;5(1). Epub 2019 Feb 1.

Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA.

Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of and gene rearrangement is characteristic of IFS, which can be detected on routine fluorescence in situ hybridization (FISH) testing. Patients with IFS typically respond well to surgical resection and chemotherapy and have an overall survival of ∼90%. Read More

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http://dx.doi.org/10.1101/mcs.a003376DOI Listing
February 2019

Desmoid-type Fibromatosis of the Breast Mimicking Carcinoma.

J Belg Soc Radiol 2019 Jan 29;103(1):13. Epub 2019 Jan 29.

GZA Hospitals, BE.

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http://dx.doi.org/10.5334/jbsr.1612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354018PMC
January 2019
1 Read

The Emerging Role of Surgery for Patients With Advanced Melanoma Treated With Immunotherapy.

J Surg Res 2018 Dec 20;236:209-215. Epub 2018 Dec 20.

Department of Surgery, Duke University, Durham, North Carolina.

Background: The emergence of immune checkpoint inhibitors (ICIs) has improved survival for patients with metastatic melanoma. The types of disease-response patterns to ICI therapy can be more complex relative to traditional chemotherapy and include mixed responses, pseudoprogression, and oligoprogression. The potential benefit of surgery after incomplete response to ICI therapy has not been explored. Read More

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http://dx.doi.org/10.1016/j.jss.2018.11.045DOI Listing
December 2018

[Resection of a Desmoid Tumor Originating from the Greater Omentum after Surgery for Colon Cancer and Liver Metastasis-A Case Report].

Gan To Kagaku Ryoho 2018 Dec;45(13):2444-2446

Dept. of Surgery, Suita Municipal Hospital.

Here, we report the case of a 66-year-old male patient who previously underwent resection of sigmoid colon cancer and its liver metastasis. His follow-up contrast-enhanced CT scan revealed a mass shadow at around the gastrosplenic ligament, which gradually increased in size. Because it could not be pathologically diagnosed by transgastric EUS-FNA, en bloc resection wasperformed surgically for the tumor in the greater omentum. Read More

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December 2018
1 Read

En bloc resection for intra-abdominal/retroperitoneal desmoid-type fibromatosis with adjacent organ involvement: A case series and literature review.

Biosci Trends 2018 ;12(6):620-626

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education, Beijing), Department of Hepato-PancreatoBiliary Surgery, Peking University Cancer Hospital and Institute.

Surgical treatment for intra-abdominal/retroperitoneal desmoid-type fibromatosis (IA/RPDF) is still controversial. Studies regarding en bloc resection in IA/RPDF with adjacent organ involvement are scanty. This study aims to evaluate the safety and effectiveness of en bloc resection in IA/RPDF with adjacent organ involvement. Read More

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http://dx.doi.org/10.5582/bst.2018.01285DOI Listing
January 2018

Cryotherapy efficacy and safety as local therapy in surgical treatment of musculoskeletal tumours. A retrospective case series of 143 patients.

J Biol Regul Homeost Agents 2018 Nov-Dec;32(6 Suppl. 1):65-70

Second Orthopedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Italy.

Cryotherapy, also called Cryoablation (CA), is a technique that provides a local treatment to various pathological conditions. In Musculoskeletal tumours management, Cryoablation is well accepted and validated as a treatment in palliative cures for metastatic patients. Recently, CA has been proposed also as an alternative to radiofrequency ablation in osteoid osteoma and other benign tumour treatment with promising results. Read More

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January 2019
2 Reads

Desmoid Tumor Presenting as a Typical Cervical Dumbbell Tumor:A Case Report and Literature Review.

World Neurosurg 2019 Jan 10. Epub 2019 Jan 10.

Department of Spinal Surgery, Affiliated Hospital of Southwest Medical University, Southwest Medical University, Luzhou, China. Electronic address:

Background: Dumbbell-shaped tumor is a type of the inner and outer cervical spinal canal tumor, and most of them are neurogenic tumors. Desmoid tumor is a rare tumor, and no case of them involving intervertebral foramen formed dumbbell-shaped in cervical spine have been reported before in English literature. Here we report a case of desmoid tumor arising in the cervical spine which is presented as typical dumbbell-shaped tumor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750193003
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http://dx.doi.org/10.1016/j.wneu.2019.01.001DOI Listing
January 2019
5 Reads

A Desmoid Tumor Involving the Subscapularis Muscle: A Case Report.

JBJS Case Connect 2019 Jan 9. Epub 2019 Jan 9.

Massachusetts General Hospital, Boston, Massachusetts.

Case: A 31-year-old woman developed worsening pain and paresthesia in the neck, shoulder, and arm over a period of 6 years. Magnetic resonance imaging revealed a soft-tissue mass in the subscapular region, with likely involvement of the scapula and the subscapularis muscle. The mass was resected, and the final histologic diagnosis was desmoid-type fibromatosis. Read More

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http://dx.doi.org/10.2106/JBJS.CC.18.00184DOI Listing
January 2019

Recurrent Desmoid Tumor of the Neck: A Case Report of a Benign Disease with Aggressive Behavior.

Case Rep Otolaryngol 2018 28;2018:6573587. Epub 2018 Nov 28.

Department of Otorhinolaryngology, University of Crete Medical School, Heraklion, Crete, Greece.

We present a case of a desmoid tumor recurrence in a patient with a history of a resected desmoid tumor of the right neck area with free surgical margins six months earlier. The neoplasm was found to invade the parapharyngeal space, and wide excision was performed including most of the sternocleidomastoid muscle (SCM), the thrombosed internal jugular vein (IJV), and the infiltrated spinal accessory nerve (SAN). The histopathologic findings displayed free microscopic margins, with close margins at the site of the parapharyngeal space extension. Read More

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https://www.hindawi.com/journals/criot/2018/6573587/
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http://dx.doi.org/10.1155/2018/6573587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304189PMC
November 2018
1 Read

A giant mesenteric fibromatosis involving the muscular layer of the colon wall: A case report.

Medicine (Baltimore) 2019 Jan;98(1):e14015

Department of Hepatobiliary Surgery, Clinical Nutrition Support Center, Binzhou Medical University Hospital.

Rationale: Mesenteric fibromatosis (MF) is a rare tumor whose biological behavior is intermediate between benign fibrous neoplasms and fibrosarcomas, and the characteristic of these tumors are local aggressive lesions which is prone to local recurrence but non-metastasizing. The common symptom is abdominal distention or painless mass. We report a case of giant MF in abdominal cavity with abdominal distention as the main symptom. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901040-0006
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http://dx.doi.org/10.1097/MD.0000000000014015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344171PMC
January 2019
3 Reads

Sino-orbital desmoid tumor in a pediatric patient - Case report with review of literature.

Orbit 2018 Dec 27:1-9. Epub 2018 Dec 27.

e Department of Pediatric Oncology , National University Health System , Singapore , Singapore.

We report a case of a 2-year-old female who presented with bilateral progressive proptosis, visual loss, nasal obstruction, and breathing difficulty. Magnetic resonance imaging revealed a large sino-orbital mass that was extending to the orbital apex and skull base. An initial diagnosis of rhabdomyosarcoma was made elsewhere on the basis of the presence of round and spindle cell tumor. Read More

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http://dx.doi.org/10.1080/01676830.2018.1556306DOI Listing
December 2018
2 Reads

Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor.

Laryngoscope 2018 Dec 25. Epub 2018 Dec 25.

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina Hospital, Chapel Hill, North Carolina, U.S.A.

Desmoid tumors are exceedingly rare within the larynx and cause significant morbidity due to their locally aggressive and infiltrative nature. Surgery is the mainstay of treatment with previous reports describing total and near-total laryngectomy for cure. We present a case of recurrent glottic desmoid tumor managed with hemilaryngectomy and reconstructed with temporoparietal free tissue, rib, and buccal grafts. Read More

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http://dx.doi.org/10.1002/lary.27756DOI Listing
December 2018
2 Reads

Sorafenib for Advanced and Refractory Desmoid Tumors.

N Engl J Med 2018 12;379(25):2417-2428

From Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center (M.M.G., W.D.T., N.H., N.P.A., R.A.L., Y.M., R.Y.) and Columbia University Vagellos College of Physicians and Surgeons and New York Presbyterian Hospital (L.H.S., G.K.S.), New York, and Northwell Cancer Institute and Cold Spring Harbor Laboratory, Lake Success (R.G.M.) - all in New York; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN (M.R.M.); Washington University School of Medicine, St. Louis (B.A.V.T.); M.D. Anderson Cancer Center, University of Texas, Houston (V.R.); Mayo Clinic in Florida, Jacksonville (S.A.); Yale University, New Haven, CT (H.A.D.); University Health Network Princess Margaret Cancer Centre, Toronto (A.A.G.); University of Iowa-Holden Comprehensive Cancer Center, Iowa City (M.M.M.); University of Alabama at Birmingham Cancer Center, Birmingham (R.M.C.); Fox Chase Cancer Center, Philadelphia (S.M.); Georgetown University, Lombardi Comprehensive Cancer Center, Washington, DC (M.J.P.); Duke Cancer Institute, Duke University Medical Center, Durham (R.F.R.), and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill (E.B.) - both in North Carolina; Dayton National Cancer Institute Community Oncology Research Program, Dayton, OH (T.S.); National Cancer Institute, Bethesda, MD (J.J.W.); and the Alliance Statistics and Data Center, Mayo Clinic, Scottsdale, AZ (A.C.D.).

Background: Desmoid tumors (also referred to as aggressive fibromatosis) are connective tissue neoplasms that can arise in any anatomical location and infiltrate the mesentery, neurovascular structures, and visceral organs. There is no standard of care.

Methods: In this double-blind, phase 3 trial, we randomly assigned 87 patients with progressive, symptomatic, or recurrent desmoid tumors to receive either sorafenib (400-mg tablet once daily) or matching placebo. Read More

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http://dx.doi.org/10.1056/NEJMoa1805052DOI Listing
December 2018
13 Reads

Clinical prognostic factors for pediatric extra-abdominal desmoid tumor: analyses of 66 patients at a single institution.

World J Surg Oncol 2018 Dec 18;16(1):237. Epub 2018 Dec 18.

Department of Pediatric Orthopaedic, Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai, 201102, China.

Background And Purpose: Pediatric desmoid tumor (PDT) is rare and has a high local recurrence rate. The purpose of the present study was to analyze clinical risk factors of local recurrence in PDT patients.

Materials And Methods: We reviewed clinical data of 66 PDT patients from 2004 to 2015. Read More

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http://dx.doi.org/10.1186/s12957-018-1536-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299634PMC
December 2018
1 Read

Desmoid Fibromatosis Mimicking Metastatic Recurrence After Pancreatectomy for Pancreatic Adenocarcinoma.

Mayo Clin Proc Innov Qual Outcomes 2018 Dec 20;2(4):392-397. Epub 2018 Sep 20.

Department of Radiology, Mayo Clinic, Rochester, MN.

Desmoid fibromatosis is a rare, neoplastic tumor known for its aggressive local invasion and recurrence after surgery. Tumors can occur sporadically or associated with familial adenomatous polyposis. We present 3 cases of desmoid fibromatosis postpancreatectomy for pancreatic adenocarcinoma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25424548183008
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http://dx.doi.org/10.1016/j.mayocpiqo.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260471PMC
December 2018
7 Reads

Abnormal Presentation of Aggressive Fibromatosis After Radiotherapy for Keloids: Case Report and Brief Literature Review.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Rationale: Keloids, dermal fibroproliferative lesions, often occur secondary to skin injury and extend beyond the margins of the original lesion. Aggressive fibromatosis (AF) is a rare condition arising from fibroblasts and is characterized clinically as a nonmetastasizing but locally invasive tumor. In this work, we present the case of a patient who developed AF in the chest 3 years after surgery and postoperative radiotherapy for keloids. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001675DOI Listing
December 2018
4 Reads

Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients.

Int J Radiat Oncol Biol Phys 2018 Dec 12. Epub 2018 Dec 12.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Purpose: To update our experience with long-term outcomes in patients with desmoid fibromatosis treated with radiation therapy (RT) and to characterize factors associated with increased risk of local recurrence.

Methods And Materials: We reviewed the records of 209 consecutive patients with desmoid fibromatosis treated with RT, either alone or as combined-modality therapy (CMT) with surgery, at our institution from 1965 to 2015.

Results: Median follow-up time was 98 months (range, 1-509 months). Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.012DOI Listing
December 2018

Aggressive fibromatosis of the parotid gland.

Ear Nose Throat J 2018 Dec;97(12):E28-E30

Department of Otolaryngology-Head and Neck Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

Extra-abdominal fibromatosis (EAF) is a rare, locally aggressive tumor that originates in fascial structures. It accounts for less than 0.3% of all tumors diagnosed. Read More

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December 2018
14 Reads

A Case of Primary Intra-abdominal Synovial Sarcoma.

Indian J Surg Oncol 2018 Dec 22;9(4):636-639. Epub 2018 May 22.

2Department of General and Gastrointestinal Surgery, Medical Trust Hospital, M.G. Road, Kochi, Kerala 682016 India.

Synovial sarcomas are relatively common intermediate-to-high-grade malignant soft tissue tumors, often with an initial indolent course. And among the sarcomas primary intra-abdominal synovial sarcoma is a relatively rare entity that may present with an abdominal mass and diagnosis is usually confirmed by immunohistochemistry. The authors report a case of a 46-year-old man who presented with a large palpable abdominal mass. Read More

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http://dx.doi.org/10.1007/s13193-018-0783-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265165PMC
December 2018
1 Read

Clinical, histological and therapeutic modern approach of Ledderhose disease.

Rom J Morphol Embryol 2018 ;59(3):691-697

Department of Anesthesiology and Intensive Care, Emergency Clinical Hospital of Bucharest, Romania;

Ledderhose disease or plantar fibromatosis is a rare hyperproliferative disorder of the plantar aponeurosis, clinically characterized by nodules situated especially on the medial border of the foot. It is histopathologically associated with Dupuytren's disease. This disease has some risk factors, like old age, alcohol or nicotine abuse, liver dysfunction, trauma or exposure to vibrations and autoimmune disorders, but the exact etiology is still unknown. Read More

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December 2018
22 Reads

Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations.

Eur J Surg Oncol 2018 Oct 18. Epub 2018 Oct 18.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, the Netherlands. Electronic address:

Introduction: Sporadic desmoid-type fibromatosis (DTF) is a rare soft tissue tumor of mesenchymal origin. It is characterized by local invasive growth and unpredictable growth behavior. Three distinct mutations involving the CTNNB1 (β-catenin) gene have been identified in the vast majority of DTF tumors, which cause activation of the Wnt signaling pathway and impact prognosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07487983183143
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http://dx.doi.org/10.1016/j.ejso.2018.09.019DOI Listing
October 2018
3 Reads

Successful treatment of a recurrent chest wall desmoid tumor with cyclooxygenase-2 inhibitors.

J Thorac Cardiovasc Surg 2018 Nov 2. Epub 2018 Nov 2.

Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://dx.doi.org/10.1016/j.jtcvs.2018.10.106DOI Listing
November 2018
3 Reads

Coexistence of duodenum derived aggressive fibromatosis and paraduodenal hydatid cyst: A case report and review of literature.

World J Gastrointest Surg 2018 Nov;10(8):90-94

Department of Pathology, Inonu University Faculty of Medicine, Malatya 244280, Turkey.

Intra-abdominal aggressive fibromatosis is a locally aggressive tumor mostly originating from the mesentery or retroperitoneal space, infiltrating adjacent tissues, and very rarely metastasizing to distant organs. There are only two case reports in the English language literature where intra-abdominal aggressive fibromatosis originated from the intestinal wall. In this study, we aimed to report a case of aggressive fibromatosis originating from the muscularis propria layer of the duodenum and invading pancreas. Read More

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http://dx.doi.org/10.4240/wjgs.v10.i8.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259024PMC
November 2018
5 Reads

Desmoid tumors of the head and neck: Two decades in a single tertiary care unit and review of the literature.

Ear Nose Throat J 2018 Oct-Nov;97(10-11):362-367

Department of Otorhinolaryngology-Head and Neck Surgery, Turku University Hospital, FIN-20521, Turku, Finland.

Desmoid tumors (DTs) of the head and neck have typically been classified as extra-abdominal, although the anatomic challenges of the head and neck warrant consideration of these DTs as a special entity. We present a review of DTs and describe our series of five patients with DTs of the head and neck treated within 2 decades. Altogether, 53 patients with DTs treated surgically at a tertiary care center over a 20-year period were retrospectively reviewed. Read More

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November 2018
1 Read

Surgical excision versus observation as initial management of desmoid tumors: A population based study.

Eur J Surg Oncol 2018 Oct 25. Epub 2018 Oct 25.

Department of Surgery, University of Calgary, Calgary, AB, Canada.

Synopsis: Desmoid tumors can be safely managed with watchful waiting, including either observation alone or tamoxifen/NSAIDs. Surgery at first presentation can be associated with significant treatment burden.

Background: Immediate surgery was historically recommended for desmoid tumors. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07487983183143
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http://dx.doi.org/10.1016/j.ejso.2018.09.015DOI Listing
October 2018
6 Reads

Recurrent desmoid tumor arising from latissimus dorsi flap: A case report.

Clin Imaging 2019 Jan - Feb;53:191-194. Epub 2018 Nov 2.

Department of Radiology, University of Kentucky, 800 Rose Street, HX-302, Lexington, KY 40536-0293, United States of America. Electronic address:

Fibromatosis or desmoid tumor in the breast is a very rare benign soft tissue tumor. We report a case of recurrent desmoid tumor arising from latissimus dorsi flap after lumpectomy for breast carcinoma. To our knowledge, this is the first case of desmoid tumor arising from the latissimus dorsi flap. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08997071183029
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http://dx.doi.org/10.1016/j.clinimag.2018.10.025DOI Listing
November 2018
11 Reads

Association of MRI T2 Signal Intensity With Desmoid Tumor Progression During Active Observation: A Retrospective Cohort Study.

Ann Surg 2018 Nov 9. Epub 2018 Nov 9.

Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

Objective: The aim of this study was to identify predictors of desmoid progression during observation.

Summary Of Background Data: Untreated desmoids can grow, remain stable, or regress, but reliable predictors of behavior have not been identified.

Methods: Primary or recurrent desmoid patients were identified retrospectively from an institutional database. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003073DOI Listing
November 2018
11 Reads

HIFU for Bone Metastases and other Musculoskeletal Applications.

Semin Intervent Radiol 2018 Oct 5;35(4):261-267. Epub 2018 Nov 5.

Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

High-intensity focused ultrasound (HIFU) is a totally noninvasive procedure that has shown promising results in the management of numerous malignant and nonmalignant conditions. Under magnetic resonance or ultrasound guidance, high-intensity ultrasound waves are focused on a small, well-defined target region, inducing biologic tissue heating and coagulative necrosis, thus resulting in a precise and localized ablation. This treatment has shown both great safety and efficacy profiles, and may offer a multimodal approach to different diseases, providing pain palliation, potential local tumor control, and, in some cases, remineralization of trabecular bone. Read More

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http://dx.doi.org/10.1055/s-0038-1673363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218253PMC
October 2018
1 Read

Desmoid fibromatosis in the foot: A case report and literature review.

Medicine (Baltimore) 2018 Nov;97(44):e13109

Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Rationale: Desmoid fibromatosis is a rare benign neoplasm arising from musculoaponeurotic structures with the potential to infiltrate local tissues and recur locally. While the commonly affected regions are the shoulder, chest wall and back, thigh, head and neck, localization in the foot is rare and only a few cases have been reported. Deep-seated lesions of foot tend to spread along the fascia and nerve or tendon sheaths. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811020-0007
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http://dx.doi.org/10.1097/MD.0000000000013109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221670PMC
November 2018
6 Reads

Immunohistochemical correlates of recurrent genetic alterations in sarcomas.

Genes Chromosomes Cancer 2019 02 19;58(2):111-123. Epub 2018 Dec 19.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Accurate diagnosis of sarcomas relies on the integration of clinical, histopathological and molecular features. Our understanding of the latter has increased dramatically in recent years with the application of high-throughput sequencing. Concomitantly, the role of immunohistochemistry has expanded as genomic alterations have been exploited by the development of diagnostic markers that serve as surrogates for their detection. Read More

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http://doi.wiley.com/10.1002/gcc.22700
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http://dx.doi.org/10.1002/gcc.22700DOI Listing
February 2019
2 Reads

Oral and Extraoral Intermediate Tumors: Are MMP-9 and Ki-67 Biomarkers Correlated to Their High Recurrence Rates?

Appl Immunohistochem Mol Morphol 2018 Oct 24. Epub 2018 Oct 24.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MA.

Intermediate tumors of the head and neck fall in the borderline category. They are clinically aggressive tumors with no malignant phenotyping. They are locally infiltrative and have high recurrence rate with less chances to metastasize. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000703DOI Listing
October 2018
6 Reads

Extra-abdominal Desmoid Tumor Mimicking Cervical Spine Schwannoma.

Cureus 2018 Aug 14;10(8):e3145. Epub 2018 Aug 14.

Neurosurgery, University of Missouri, Columbia, USA.

Extra-abdominal desmoid tumors (DTs) are rare tumors of apparent fibroblastic origin with unpredictable clinical behavior. Though histologically benign and slow growing, DTs can be proliferative, aggressive tumors, invading the surrounding areas. DTs located extra-abdominally are most commonly found in the extremities or proximal structures like the shoulders, chest wall, and neck. Read More

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https://www.cureus.com/articles/9489-extra-abdominal-desmoid
Publisher Site
http://dx.doi.org/10.7759/cureus.3145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188173PMC
August 2018
13 Reads

Aggressive fibromatosis in pediatric population-A case series.

Int J Surg Case Rep 2018 4;52:45-48. Epub 2018 Oct 4.

Department of Surgery, Aga Khan University Hospital, Stadium Road, P. O. Box 3500 Karachi 74800, Pakistan. Electronic address:

Introduction: Aggressive fibromatosis or Desmoid fibromatosis is a benign tumor which originated form mesenchymal tissues of the body. This tumor has strong potential of recurrence and infiltration but it does not metastasize to other organs of the body. This case series is focused to determine the treatment outcomes for pediatric patients of aggressive fibromatosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183040
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http://dx.doi.org/10.1016/j.ijscr.2018.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187009PMC
October 2018
1 Read

Unusual complication in patient with Gardner's syndrome: Coexistence of triple gastrointestinal perforation and lower gastrointestinal bleeding: A case report and review of literature.

World J Clin Cases 2018 Sep;6(10):393-397

Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya 44280, Turkey.

Gardner's syndrome (GS) is a rare syndrome with autosomal dominant inheritance, which is characterized by multiple intestinal polyps, dental anomalies, desmoid tumors, and soft tissue tumors. All gastrointestinal symptoms seen in GS are associated with the underlying familial adenomatosis polyposis and abdominal desmoid tumors, with the most common symptoms being anemia, lower gastrointestinal bleeding, abdominal pain, diarrhea, obstruction, and mucous defecation. To our best knowledge, no case of GS that has presented with gastrointestinal perforation and bleeding has ever been reported in the English language medical literature. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i10.393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163136PMC
September 2018
4 Reads

Dedifferentiated Liposarcoma With Myofibroblastic Differentiation.

Arch Pathol Lab Med 2018 Oct;142(10):1159-1163

From the Department of Pathology, University of Michigan, Ann Arbor.

Context.—: Liposarcoma is divided into myxoid, pleomorphic, well-differentiated, and dedifferentiated subtypes. Dedifferentiated liposarcoma displays the greatest histomorphologic diversity, including a subset with myofibroblastic differentiation that shares similarities with a spectrum of reactive, benign, and malignant soft tissue lesions. Read More

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http://dx.doi.org/10.5858/arpa.2018-0205-RADOI Listing
October 2018
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Silicone breast implant associated fibromatosis.

J Surg Case Rep 2018 Sep 27;2018(9):rjy249. Epub 2018 Sep 27.

Division of Breast Surgical Oncology, Department of Surgery, University of Arkansas for Medical Sciences and the Winthrop P. Rockefeller Cancer Institute, Little Rock, AR, USA.

Extra-abdominal desmoid tumors, also known as aggressive or deep fibromatosis, are uncommon soft tissue tumors that rarely involve the breast. Although the exact etiology is unknown, the development of these tumors has been correlated with sites of previous trauma, surgery or in association with familial adenomatous polyposis. Clinically, breast fibromatosis is often mistaken for carcinoma but lacks metastatic potential. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjy24
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http://dx.doi.org/10.1093/jscr/rjy249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158700PMC
September 2018
22 Reads

Evidence of hydroxyurea activity in children with pretreated desmoid-type fibromatosis: A new option in the armamentarium of systemic therapies.

Pediatr Blood Cancer 2019 Jan 30;66(1):e27472. Epub 2018 Sep 30.

Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.

Introduction: The treatment paradigm in desmoid-type fibromatosis (DF) has changed in recent years from a surgery-based strategy to a multidisciplinary approach that includes systemic therapies. Among various medical therapies, hydroxyurea has been considered of potential interest. This case series summarizes the experience gained at four centers using hydroxyurea in relapsing DF. Read More

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http://dx.doi.org/10.1002/pbc.27472DOI Listing
January 2019
3 Reads
2.562 Impact Factor

Hump-like giant desmoid tumor of the chest: a postresectional reconstruction challenge.

AME Case Rep 2017 17;1. Epub 2017 Nov 17.

Department of Thoracic Surgery, Policlinico Tor Vergata University, Rome, Italy.

Desmoid tumors (DT) are rare neoplasms with unknown etiology arising from musculoaponeurotic structures. Chest wall localization is uncommon and has been associated with high recurrence rate unless radical resection with negative margins is carried out. Postresectional reconstruction can be challenging in presence of giant lesions and might require adoption of complex reconstruction methods including use of well vascularized muscle flaps. Read More

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http://acr.amegroups.com/article/view/4160/4892
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http://dx.doi.org/10.21037/acr.2017.11.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155693PMC
November 2017
12 Reads

Giant Intra-Abdominal Desmoid Tumor in a Young Male without History of Surgery, Trauma, or Familial Adenomatous Polyposis.

Case Rep Surg 2018 4;2018:9825670. Epub 2018 Sep 4.

Department of Surgery, Akashi Medical Center, Hyogo, Japan.

Desmoid tumors are rare, monoclonal myofibroblastic neoplasms that occur in the extremities, the trunk, and the abdominal cavity. We present a case that is significant for its rarity and for consideration of its treatment plan. A 17-year-old male reported swelling of his abdomen and abdominal pain. Read More

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http://dx.doi.org/10.1155/2018/9825670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142721PMC
September 2018
13 Reads

Pancreatic desmoid tumor: A rare case with radiologic-pathologic correlation.

Radiol Case Rep 2018 Oct 18;13(5):1079-1083. Epub 2018 May 18.

Chief of the anatomic pathology department, Hotel-Dieu hospital, CHU de Quebec, Quebec, Canada.

A 39-year-old female patient was referred to our tertiary oncologic center for additional investigations relating to a suspect pancreatic tail lesion. An abdominal computed tomography scan and magnetic resonance imaging scan showed a solid lesion demonstrating progressive enhancement. Complete resection was obtained and the final diagnosis was that of a desmoid tumor of the pancreas, an exceptionally rare tumor demonstrating overlap with other solid and cystic lesions of the pancreas [1]. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19300433183012
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http://dx.doi.org/10.1016/j.radcr.2018.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137398PMC
October 2018
2 Reads

Desmoid-type fibromatosis mimicking cystic retroperitoneal mass: case report and literature review.

BMC Med Imaging 2018 09 17;18(1):29. Epub 2018 Sep 17.

Department of Radiology, Korea University Guro Hospital, Korea University College of Medicine, 80 Guro-dong, Guro-gu, Seoul, 152-703, South Korea.

Background: Retroperitoneal desmoid-type fibromatosis (DF) is an uncommon mesenchymal neoplasm presenting as a firm mass with locally aggressive features. It usually manifests as a well-circumscribed or ill-defined, solid mass on cross-sectional imaging. Cystic changes of DF have been described in the literature in association with prolonged medical treatment or abscess formation. Read More

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http://dx.doi.org/10.1186/s12880-018-0265-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142631PMC
September 2018
2 Reads