Search our Database of Scientific Publications and Authors

I’m looking for a

    2524 results match your criteria Desmoid Tumor

    1 OF 51

    Gradually shrinking intra-abdominal desmoid tumor derived from the stomach in a young boy: a case report.
    Surg Case Rep 2017 Dec 20;3(1):54. Epub 2017 Apr 20.
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
    Background: Intra-abdominal desmoid tumors, particularly those derived from the stomach, are rare. Such tumors are associated with a history of familial adenomatous polyposis (FAP), trauma, or surgical procedures in general. In addition, spontaneous shrinking of an intra-abdominal desmoid tumor is rarer. Read More

    Human microRNA expression in sporadic and FAP-associated desmoid tumors and correlation with beta-catenin mutations.
    Oncotarget 2017 Mar 19. Epub 2017 Mar 19.
    General Surgery and Liver Transplantation Unit, Department of Emergency and Organ Transplantation (DETO), University of Bari "Aldo Moro", Bari, Italy.
    Desmoid tumors (DT) are rare, benign, fibroblastic neoplasm with challenging histological diagnosis. DTs can occur sporadically or associated with the familial adenomatous polyposis coli (FAP). Most sporadic DTs are associated with β-catenin gene (CTNNB1) mutations, while mutated APC gene causes FAP disease. Read More

    Desmoid-type fibromatosis in a boy with Down syndrome.
    Pediatr Int 2017 Apr 18. Epub 2017 Apr 18.
    Department of Pediatrics, Okayama University Hospital, Okayama, Japan.
    Patients with Down syndrome (DS) have a markedly higher incidence of childhood leukemia, but a lower incidence of most solid tumors, compared with age-matched euploid individuals. Trisomy 21 might be protective against tumorigenesis because of several tumor suppressive mechanisms. Desmoid-type fibromatosis (DF) is a rare monoclonal, fibroblastic proliferation characterized by a variable clinical course. Read More

    Desmoid Fibromatosis of the Abdominal Wall: Surgical Resection and Reconstruction with Biological Matrix Egis(®).
    Case Rep Oncol 2017 Jan-Apr;10(1):205-211. Epub 2017 Feb 17.
    Surgical Oncology Unit, Veneto Insitute of Oncology, IOV-IRCCS, Padua, Italy.
    Desmoid tumor is a rare monoclonal fibroblast proliferation that is regarded as benign. The clinical management of desmoid tumors is very complex and requires a multidisciplinary approach because of the unpredictable disease course. For those cases localized in the anterior abdominal wall, symptomatic and unresponsive to medical treatment, radical resection and reconstruction with a prosthetic device are indicated. Read More

    Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).
    J Clin Oncol 2017 Mar 28:JCO2016711994. Epub 2017 Mar 28.
    Shivaani Kummar, Geraldine O'Sullivan Coyne, Khanh T. Do, Baris Turkbey, Paul S. Meltzer, Eric Polley, Peter L. Choyke, Robert Meehan, Yvonne Horneffer, Ann Lih, Amul Choudhary, Sandra A. Mitchell, Lee J. Helman, James H. Doroshow, and Alice P. Chen, National Cancer Institute, National Institutes of Health, Bethesda; and Rasa Vilimas and Lamin Juwara, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD.
    Purpose Desmoid tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts. In general, they are slow growing and do not metastasize; however, locally aggressive desmoid tumors can cause severe morbidity and loss of function. Disease recurrence after surgery and/or radiation and diagnosis of multifocal desmoid tumors highlight the need to develop effective systemic treatments for this disease. Read More

    Partial fasciectomy is a useful treatment option for symptomatic plantar fibromatosis.
    Foot (Edinb) 2017 Feb 21;31:31-34. Epub 2017 Feb 21.
    Royal Liverpool and Broadgreen University Hospitals NHS Trust, Prescot Street, Liverpool, L7 8XP, United Kingdom.
    Plantar fibromatosis is a rare, benign fibroproliferative disorder of the plantar fascia. It is considered as a low-grade tumour and it can be locally aggressive. It can present as painful swelling with impairment of local function. Read More

    Solid-Cystic Pancreatic Tail Desmoid Tumor with Beta-Catenin Positivity.
    ACG Case Rep J 2017 15;4:e40. Epub 2017 Mar 15.
    Department of Gastroenterology, Hepatology and Nutrition, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX; Ertan Digestive Disease Center, Memorial Hermann Hospital, Texas Medical Center, Houston, TX.

    Abdominal wall reconstruction after desmoid type fibromatosis radical resection: Case series from a single institution and review of the literature.
    Int J Surg Case Rep 2017 Mar 1;33:167-172. Epub 2017 Mar 1.
    Departament of Surgery, Division of Surgical Clinic III, Hospital das Clínicas, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
    Background: Abdominal wall desmoid type fibromatosis management has been changing over recent years, from an aggressive approach towards a more conservative one. When radical resection is indicated, the surgical team faces the challenge of abdominal wall reconstruction, for which optimal technique is still debated. The present study reports the experience from a single center with abdominal closures after desmoid type fibromatosis resection. Read More

    A Patient With Desmoid Tumors and Familial FAP Having Frame Shift Mutation of the APC Gene.
    Acta Med Iran 2017 Feb;55(2):134-138
    Department of Medical Genetics, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.
    Desmoids tumors, characterized by monoclonal proliferation of myofibroblasts, could occur in 5-10% of patients with familial adenomatous polyposis (FAP) as an extra-colonic manifestation of the disease. FAP can develop when there is a germ-line mutation in the adenomatous polyposis coli gene. Although mild or attenuated FAP may follow mutations in 5΄ extreme of the gene, it is more likely that 3΄ extreme mutations haveamore severe manifestation of thedisease. Read More

    Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: Final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG).
    Eur J Cancer 2017 May 8;76:60-67. Epub 2017 Mar 8.
    University of Heidelberg, Mannheim University Medical Center, Interdisciplinary Tumor Center Mannheim, Sarcoma Unit, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany; University of Heidelberg, Mannheim University Medical Center, Division of Surgical Oncology, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.
    Background: Desmoid tumours describe a rare monoclonal, fibroblastic proliferation characterised by an often unpredictable clinical course. Surgery is one therapeutic option for progressing patients, except if mutilating and associated with considerable function loss. Different systemic treatment approaches have been investigated and promising results could be demonstrated using imatinib. Read More

    Functional and Aesthetic Thorax Reconstruction after Desmoid Tumor Resection.
    Plast Reconstr Surg Glob Open 2017 Feb 22;5(2):e1248. Epub 2017 Feb 22.
    Plastic and Reconstructive Surgery Service, Surgical Oncology Service, and Pathology Service, Hospital Angeles Puebla, Puebla 72190, México.
    This study describes a case report of a 31-year-old patient who presented with a left thoracic tumor on costal cartilages 5 and 6 that was diagnosed as a desmoid tumor 3 years after receiving retropectoral breast implants for cosmetic reasons. The integral reconstruction of the thoracic wall, functional and aesthetic, was planned for a single surgical period. The defect secondary to the tumor resection, which left the pericardium and lung exposed, was closed using the pectoral muscle as a "pre-expanded" flap by the breast implant, and the breast aesthetic was treated bilaterally with new implants in the retromammary position. Read More

    An Unusual Location of Fibrous Hamartoma of Infancy in the Eyelid.
    Ocul Oncol Pathol 2017 Jan 6;3(1):8-10. Epub 2016 Sep 6.
    Goldschleger Eye Institute, Tel Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
    Aim: To describe the clinical, imaging, and histopathological features of fibrous hamartoma of infancy (FHI) in the eyelid, a rare differential diagnosis for eyelid lesions.

    Methods: We describe the case of a 7-month-old patient with a FHI in the eyelid that was diagnosed after surgical removal. The unique histopathological appearance of the triphasic histologic components provided the diagnosis. Read More

    The treatment of desmoid tumors associated with familial adenomatous polyposis: the results of a Japanese multicenter observational study.
    Surg Today 2017 Mar 1. Epub 2017 Mar 1.
    Department of Surgical Oncology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
    Purpose: Familial adenomatous polyposis (FAP)-associated desmoid tumor (DT) is sometimes life threatening. However, the optimal treatment for DTs has not been established. The aim of this study was to analyze the outcomes of surgical and pharmacological treatments for DT in Japanese FAP patients. Read More

    A Mesenteric Desmoid Tumor with Rapid Progression.
    Intern Med 2017 1;56(5):505-508. Epub 2017 Mar 1.
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Japan.
    We herein report the case of a rapidly progressive sporadic mesenteric desmoid tumor (DT). A 62-year-old woman presented with a 4-cm-diameter palpable mass in the left supraumbilical area. The mass showed an ill-defined margin with heterogeneous delayed enhancement on computed tomography and heterogeneous high intensity on T2-weighted magnetic resonance imaging. Read More

    Recurrent SRF-RELA Fusions Define a Novel Subset of Cellular Myofibroma/Myopericytoma: A Potential Diagnostic Pitfall With Sarcomas With Myogenic Differentiation.
    Am J Surg Pathol 2017 May;41(5):677-684
    *Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Pathology, Brigham and Women Hospital, Boston, MA.
    Cellular myofibroblastic tumors other than desmoid-type fibromatosis are often diagnostically challenging due to their relative rarity, lack of known genetic abnormalities, and expression of muscle markers which may be confused with sarcomas with myogenic differentiation. In this study we investigate the molecular alterations of a group of cellular myofibroblastic lesions with in the myofibroma and myopericytoma spectrum for better subclassification. Two index cases were studied by paired-end RNA sequencing for potential fusion gene discovery. Read More

    Risk factors for local recurrence of fibromatosis.
    Rev Esp Cir Ortop Traumatol 2017 Mar - Apr;61(2):82-87. Epub 2017 Feb 21.
    Departamento de Cirugía Ortopédica y Traumatología, Clínica Universidad de Navarra, Pamplona, Navarra, España.
    Objective: To evaluate the clinical, radiological and histological factors that can predict local recurrence of fibromatosis.

    Methods: A retrospective study was conducted on 51 patients diagnosed with fibromatosis in this hospital from 1983 to 2014. The mean follow-up was 83 months. Read More

    Desmoid tumor following abdominally-based free flap breast reconstruction.
    Gland Surg 2017 Feb;6(1):89-92
    Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.
    Desmoid tumors are fibroblastic connective tissue tumors that most commonly develop within the anterior abdominal wall. The etiology of desmoid tumors has not been well defined; however, hereditary, hormonal, traumatic, and surgery-related causes have been implicated. Desmoid tumors are believed to arise from musculoaponeurotic structures. Read More

    Sporadic desmoid tumors in the pediatric population: A single center experience and review of the literature.
    J Pediatr Surg 2017 Feb 4. Epub 2017 Feb 4.
    Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center of Israel, Petach Tikva 4941492, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel. Electronic address:
    Background/purpose: We present our long experience with desmoid tumors in children.

    Methods: Data were retrospectively collected from 17 children/adolescents treated for sporadic desmoid tumors at a tertiary pediatric hospital in 1988-2016. There were 10 girls and 7 boys aged 1-17years. Read More

    Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis.
    Br J Surg 2017 Mar;104(4):347-357
    Departments of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
    Background: Extra-abdominal desmoid-type fibromatosis (DF) is a rare, locally aggressive neoplasm that is usually managed conservatively. When treatment is indicated, it typically involves surgical resection, possibly with adjuvant radiotherapy. The indications for postoperative radiotherapy and its effectiveness are unclear. Read More

    MRgFUS for desmoid tumors within the thigh: early clinical experiences.
    J Ther Ultrasound 2017 3;5. Epub 2017 Feb 3.
    Department of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107-5705 USA.
    Background: Desmoid tumors are benign but locally aggressive non-malignant tumors derived from fibroblasts. Surgery, chemotherapy, and radiation therapy have been the mainstay of treatment, but recurrence is common and side effects can result in significant morbidity. In this case series, we highlight our experiences performing treatments in the thigh, including strategies for optimizing ablation size and safety. Read More

    Endoscopic Subtotal Fasciectomy of the Foot.
    Arthrosc Tech 2016 Dec 5;5(6):e1387-e1393. Epub 2016 Dec 5.
    Department of Orthopaedics and Traumatology, North District Hospital, Hong Kong SAR, China.
    Plantar fibromatosis is a rare benign but often locally aggressive tumor of the plantar aponeurosis. Nonsurgical treatment is the first line of treatment for symptomatic lesions. Because of the high recurrence rate associated with surgical treatment, operation is indicated only when the lesions are highly symptomatic and conservative measures fail or the diagnosis is in question. Read More

    [A Case of Familial Adenomatous Polyposis with a Desmoid Tumor Probably Communicating to the Intestinal Lumen That Was Successfully Treated with Non-Surgical Therapy].
    Gan To Kagaku Ryoho 2016 Nov;43(12):2316-2319
    Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
    A 44-year-old man with familial adenomatous polyposis underwent laparoscopic-assistedtotal proctocolectomy with ilealpouch anal anastomosis(IPAA). Computed tomography conducted 21 months after IPAA demonstrated bilateral hydronephrosis andan intra-abdominal mass with a maximal diameter of 22 cm, leading to a diagnosis of stage IV desmoid disease, according to the classification by Church and associates. Six courses of combination chemotherapy with doxorubicin plus dacarbazine were administered. Read More

    Pazopanib, a promising option for the treatment of aggressive fibromatosis.
    Anticancer Drugs 2017 Apr;28(4):421-426
    aSarcoma Unit, The Royal Marsden Hospital NHS Foundation Trust, London bDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge cThe Institute of Cancer Research, Sutton, UK.
    Desmoid tumour/aggressive fibromatosis (DT/AF) is a rare soft-tissue neoplasm that is locally aggressive but does not metastasize. There is no standard systemic treatment for symptomatic patients, although a number of agents are used. Tyrosine kinase inhibitors have recently been reported to show useful activity. Read More

    TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models.
    Genesis 2017 Jan;55(1-2)
    Developmental Biology Unit, Department of Biomedical Molecular Biology, Ghent University, Belgium.
    The targeted nuclease revolution (TALENs, CRISPR/Cas9) now allows Xenopus researchers to rapidly generate custom on-demand genetic knockout models. These novel methods to perform reverse genetics are unprecedented and are fueling a wide array of human disease models within the aquatic diploid model organism Xenopus tropicalis (X. tropicalis). Read More

    Radiotherapy in desmoid tumors : Treatment response, local control, and analysis of local failures.
    Strahlenther Onkol 2017 Apr 2;193(4):269-275. Epub 2017 Jan 2.
    Comprehensive Cancer Center, Helsinki University Hospital and University of Helsinki, PO Box 180, 00029 HUS, Helsinki, Finland.
    Background: Desmoid tumors (aggressive fibromatosis) are rare soft tissue tumors which frequently recur after surgery. Desmoid tumors arise from musculoaponeurotic tissue in the extremities, head and neck, abdominal wall, or intra-abdominally. Our aim was to examine the outcome of radiotherapy of desmoid tumors in a single institution series. Read More

    Comparison of β-Catenin and LEF1 Immunohistochemical Stains in Desmoid-type Fibromatosis and its Selected Mimickers, With Unexpected Finding of LEF1 Positivity in Scars.
    Appl Immunohistochem Mol Morphol 2016 Dec 23. Epub 2016 Dec 23.
    Departments of *Department of Pathology †Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH.
    β-catenin immunohistochemical stain can be useful in the diagnosis of many tumors including desmoid-type fibromatosis (DTF). Lymphoid enhancer-factor 1 (LEF1), a recently emerged marker, is part of the Wnt pathway with β-catenin but has not been studied in DTF. We performed LEF1 and β-catenin immunohistochemistry in DTF (n=26), superficial fibromatosis (n=19), sclerosing mesenteritis (n=12), gastrointestinal stromal tumor (n=17), and cutaneous scar (n=14) using tissue microarray and whole sections. Read More

    Fibromatosis Associated With Neuromuscular Choristoma: Evaluation by FDG PET/CT.
    Clin Nucl Med 2017 Mar;42(3):e168-e170
    From the Departments of *Radiology, †Neurosurgery, and ‡Orthopedic Surgery, Mayo Clinic, Rochester, MN.
    Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion consisting of mature skeletal muscle fibers admixed with nerve fascicles. Aggressive fibromatosis frequently develops in association with NMC, often after surgery or biopsy, but the exact pathogenesis is not known. We present a case of NMC complicated by aggressive fibromatosis evaluated by F-FDG PET/CT and examine the relationship of metabolic activity and MRI signal characteristics. Read More

    Desmoid Fibromatosis Presenting as Deep Venous Thrombosis: A Case Report and Discussion.
    Am J Case Rep 2016 Dec 20;17:967-972. Epub 2016 Dec 20.
    Department of Surgery, University of Adelaide, Adelaide, SA, Australia.
    BACKGROUND Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common, serious cardiovascular event. Predisposing factors include genetic disorders, immobility, and underlying malignancy. Soft tissue tumors are by contrast rare, but should be included in the differential etiology of DVT, especially when the patient is young and has few thrombotic risk factors. Read More

    Breast Desmoid Tumor after Ductal Carcinoma Treatment: Salvaging a DIEP Flap Reconstruction.
    Plast Reconstr Surg Glob Open 2016 Nov 23;4(11):e1142. Epub 2016 Nov 23.
    Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medicine, Houston, Tex.; and College of Medicine, Texas A&M University College of Medicine, Houston, Tex.
    Supplemental Digital Content is available in the text. Read More

    Pazopanib: a novel treatment option for aggressive fibromatosis.
    Clin Sarcoma Res 2016 1;6:22. Epub 2016 Dec 1.
    Department of Medical Oncology, Ege University Medical School, Tulay Aktas Oncology Hospital, Ege University, Izmir, Turkey.
    Background: Aggressive fibromatosis (AF), also known as desmoid tumor, is an uncommon soft tissue neoplasm. AF does not metastasize, but it is locally invasive and its propensity for recurrence after conservative resection is well documented. No effective cytotoxic treatment has been reported, hence there is a need for novel treatment strategies. Read More

    Bilateral perirenal space fibromatosis with renal infiltration: case report and review of literature.
    Radiol Case Rep 2016 Dec 19;11(4):438-443. Epub 2016 Oct 19.
    Division of Imageology, Regional Cancer Centre, Room No 26 PACS Room, Trivandrum, Kerala 695011, India.
    Fibromatosis and/or desmoid tumors which constitute less than 1% of all neoplasms and 3.0% of all soft-tissue tumors are pathologically benign proliferations of the fibroblasts but are locally aggressive with infiltrative type of growth and tendency toward recurrence. Bilateral symmetrical perirenal involvement has been described in many conditions which can be renal, subcapsular, or perirenal in origin. Read More

    Liposomal doxorubicin: Effective treatment for pediatric desmoid fibromatosis.
    Pediatr Blood Cancer 2016 Dec 1. Epub 2016 Dec 1.
    Department of Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
    Efficacy of liposomal doxorubicin (LD) in treating desmoid fibromatosis (DF) in children has not been well evaluated. This retrospective case series examines five children with progressive DF, treated with LD. We report progression-free intervals (PFIs) and radiographic as well as clinical responses for each medication received. Read More

    Desmoid Tumor of the Chest Wall Mimicking Recurrent Breast Cancer: Multimodality Imaging Findings.
    Iran J Radiol 2016 Oct 4;13(4):e31649. Epub 2016 Jul 4.
    Department of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
    Desmoid tumor of breast is a rare benign, locally aggressive tumor with a high recurrence rate. It has been associated with scar from previous breast surgery or trauma. Especially in breast cancer patients with previous operation history, it may simulate recurrent breast cancer clinically and radiologically. Read More

    Primary mesenchymal tumors of the pancreas in a single center over 15 years.
    Oncol Lett 2016 Nov 20;12(5):4027-4034. Epub 2016 Sep 20.
    Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China.
    In total, 95% of primary tumors in the pancreas are epithelial tumors; primary mesenchymal tumors at this site are extremely rare. At present, only one comprehensive study about these rare tumors has been performed. Another retrospective analysis of these rare tumors is performed in the present study, which, to the best of our knowledge, is the first to be performed in China. Read More

    Desmoid Tumours in Familial Adenomatous Polyposis: Review of 17 Patients from a Portuguese Tertiary Center.
    J Clin Diagn Res 2016 Oct 1;10(10):PC01-PC05. Epub 2016 Oct 1.
    General Surgeons, Department of Surgery, General Surgery Service, Centro Hospitalar do Porto , Largo Prof. Abel Salazar, 4099-001, Porto, Portugal .
    Introduction: Desmoid Tumours (DT) are benign tumours with an estimated incidence of 2-4 per million per year. Between 7-16% of them are associated with Familial Adenomatous Polyposis (FAP) and are mostly parietal or intra-abdominal. They are a challenge in relation to their unpredictable natural course, associated complications and difficult treatment. Read More

    UK guidelines for the management of soft tissue sarcomas.
    Clin Sarcoma Res 2016 15;6:20. Epub 2016 Nov 15.
    Royal Marsden NHS Foundation Trust, London, SW3 6JJ UK.
    Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location means that developing evidence-based guidelines is complicated by the limitations of the data available. However, this makes it more important that STS are managed by teams, expert in such cases, to ensure consistent and optimal treatment, as well as recruitment to clinical trials, and the ongoing accumulation of further data and knowledge. Read More

    Desmoplastic fibroma of the distal tibia: A case report of a minimally invasive histological diagnosis.
    Mol Clin Oncol 2016 Nov 19;5(5):537-539. Epub 2016 Sep 19.
    Department of Diagnostic Imaging, Arcispedale Santa Maria Nuova-IRCCS, I-42100 Reggio Emilia, Italy.
    Desmoplastic fibroma (DF) is a benign, rare fibroblastic intraosseous neoplasm histologically resembling a desmoid soft tissue tumor. Although classified as benign, DF frequently exhibits an aggressive behavior, has a moderate-to-high recurrence rate, and often causes pathological fractures and extensive bone destruction. This case report presents an incidentally detected DF of the tibia, which was diagnosed using a minimally invasive approach. Read More

    Iodine-125 Interstitial Brachytherapy for Pediatric Desmoid-Type Fibromatosis of the Head and Neck: A Case Report.
    J Oral Maxillofac Surg 2017 Apr 29;75(4):768.e1-768.e11. Epub 2016 Oct 29.
    Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China. Electronic address:
    Desmoid-type fibromatosis (DF) is a locally aggressive benign soft tissue tumor. It is rarely observed in the head and neck region and is particularly uncommon in the parotid gland. This report describes the case of a 32-month-old girl with DF of the head and neck. Read More

    Increasing Role of Image-Guided Ablation in the Treatment of Musculoskeletal Tumors.
    Cancer J 2016 Nov/Dec;22(6):401-410
    From the Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN.
    In the last decade, percutaneous treatment of musculoskeletal (MSK) tumors has become more established in routine clinical care while also undergoing a number of advancements. Ablative techniques to palliate painful skeletal metastases have gained wide acceptance, while goals for ablation have evolved to include local control of oligometastases and desmoid tumors. Bone consolidation or augmentation is now frequently used in conjunction with or instead of ablation of skeletal tumors to stabilize pathologic fractures or prevent further morbidity that could result from fractures caused by tumor progression. Read More

    Management strategies in Lynch syndrome and familial adenomatous polyposis: a national healthcare survey in Japan.
    Cancer Sci 2017 Feb;108(2):243-249
    Tokyo Medical and Dental University, Tokyo, Japan.
    Lynch syndrome (LS) and familial adenomatous polyposis (FAP) are major sources of hereditary colorectal cancer (CRC) and are associated with other malignancies. There is some heterogeneity in management strategies in Japan. We undertook a survey of management of hereditary CRC in hospitals that are members of the Japan Society of Colorectal Cancer Research. Read More

    A case of thyroid fibromatosis, a rare lesion of this gland.
    Endocrinol Diabetes Metab Case Rep 2016 11;2016. Epub 2016 Oct 11.
    Serviço de Endocrinologia; Unidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa, Francisco Gentil, Lisbon, Portugal; NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
    Thyroid fibromatosis is a very rare lesion; to our knowledge, there are only four cases reported in the medical literature. Herein, we report the clinical case of a woman with thyroid fibromatosis with a long follow-up (11 years). A 63-year-old female patient, with an increasing multinodular goitre without compressive symptoms, was admitted to total thyroidectomy. Read More

    Does routine colonoscopy help diagnose familial adenomatous polyposis in patients presenting with desmoid tumors but no gastrointestinal symptoms?
    Int J Colorectal Dis 2017 Jan 14;32(1):151-154. Epub 2016 Nov 14.
    Department of Surgery, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam, 13620, South Korea.
    Purpose: Desmoid tumor (DT) is a rare myofibroblastic proliferative neoplasm, but can occur in up to 26% of patients with familial adenomatous polyposis (FAP). Therefore, DT may be an extraintestinal manifestation of FAP that precedes the development of advanced malignancies. The aim of this study was to identify the incidence of polyps in DT patients and investigate value of colonoscopy for diagnosis of FAP in DT patients without gastrointestinal symptoms. Read More

    Cytohistological and immunohistochemical characteristics of spindle-shaped mesenchymal neoplasms occurring in the gastrointestinal tract.
    Scand J Gastroenterol 2017 Mar 6;52(3):291-299. Epub 2016 Nov 6.
    a Department of Human Pathology of adult and evolutive age "Gaetano Barresi" , University of Messina, A.O.U. "Policlinico G.Martino" , Messina , Italy.
    The purpose of the present review is to analyze the cytohistological and immunohistochemical characteristics of spindle-shaped mesenchymal gastrointestinal neoplams (MGNs), a group of unusual neoplastic conditions with different biological behavior. These tumors exhibit clinical pictures strictly related to the site of origin and dimensions, even if they appear generally with an intramural localization. This latter point may suggest an useful application of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), mainly followed by the cell-block procedure (CBP) in the differential diagnostic approach. Read More

    Rapid progression of a pregnancy-associated intra-abdominal desmoid tumor in the post-partum period: A case report.
    Int J Surg Case Rep 2016 26;29:30-33. Epub 2016 Oct 26.
    Department of Surgery, Division of General and Oncologic Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, United States. Electronic address:
    Introduction: The clinical behavior of desmoid tumors can be unpredictable, particularly when they arise in the ante-partum or post-partum period. We present a case of an intra-abdominal desmoid tumor that was identified in the ante-partum period, progressed rapidly in the post-partum period, and was subsequently resected.

    Presentation Of Case: The patient is a 19 year-old female who was found to have a 12cm intra-abdominal mass on a fetal assessment ultrasound. Read More

    [Desmoid tumors in an adolescent girl with familial adenomatous polyposis].
    Arch Pediatr 2016 Nov 28;23(11):1141-1145. Epub 2016 Sep 28.
    Service de pédiatrie, centre hospitalier Jacques-Monod, 29, avenue Pierre-Mendès, 76600 Le Havre, France. Electronic address:
    Desmoid tumors (DT) are rare and nonmetastasizing fibroblastic neoplasms, characterized by local invasiveness. They occur sporadically or arise in the context of familial adenomatous polyposis (FAP; 5-10% of cases). Most cases develop sporadically in young adults, but some cases also occur in children. Read More

    Sporadic desmoid tumors of the abdominal wall: the results of surgery.
    Tumori 2016 Dec 3;102(6):582-587. Epub 2016 Sep 3.
    Department of Surgical Oncology, Humanitas Clinical and Research Center, Milan - Italy.
    Purpose: Before the wait-and-see policy became the standard approach in abdominal wall desmoid tumors, surgery was performed on a systematic basis. Surgery remains indicated for progressing tumors but its extent is debatable. The abdominal wall is a common site of origin of sporadic desmoids, usually associated with a favorable prognosis. Read More

    1 OF 51