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    1 OF 85

    Melanoma in situ mimicking a Lichen planus-like keratosis.
    Acta Biomed 2018 Jan 16;88(4):496-498. Epub 2018 Jan 16.
    General and Specialist Surgery Department, Plastic Surgery Division, University of Siena, Italy.
    The incidence of melanoma has steadily increased over the past three decades. Melanoma in situ (MIS),  defined as melanoma that is limited to the epidermis, contributes to a disproportionately high percentage of this rising incidence. Amelanotic melanoma presents as an erythematous macule or plaque and may initially be misdiagnosed as an inflammatory disorder. Read More

    Dermoscopy of basal cell carcinoma.
    Clin Exp Dermatol 2018 Jan 17. Epub 2018 Jan 17.
    Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
    Dermoscopy is widely used in dermatological practice. The method increases the accuracy of basal cell carcinoma (BCC) detection. Pigmented and nonpigmented variants of basal cell carcinoma present different dermoscopic features. Read More

    Dermoscopy versus reflectance confocal microscopy for the diagnosis of lentigo maligna.
    J Eur Acad Dermatol Venereol 2018 Jan 17. Epub 2018 Jan 17.
    Department of Dermatology, University Hospital of St-Etienne, Saint-Etienne, France.
    Background: Several dermoscopic and in vivo reflectance confocal microscopy (RCM) diagnostic criteria of lentigo maligna (LM)/lentigo maligna melanoma (LMM) have been identified. However, no study compared the diagnostic accuracy of these techniques.

    Objective: We evaluated the diagnostic accuracy of dermoscopy and RCM for LM/LMM using a holistic assessment of the images. Read More

    Acquired melanocytic naevus phenotypes and MC1R genotypes in Han Chinese: a cross-sectional study.
    PeerJ 2017 20;5:e4168. Epub 2017 Dec 20.
    Dermatology Research Centre, The University of Queensland Diamantina Institute, Brisbane, Queensland, Australia.
    Background: Early detection and treatment are the most important elements in reducing the incidence of melanoma deaths. Acquired melanocytic naevi (AMN) are well-known precursors of melanoma but most of our knowledge on the clinico-dermoscopic phenotypes of AMN is based on studies in European-background populations, particularly American and Australian populations. There has been little research in Chinese Han populations on clinico-dermoscopic variability of naevi or how naevi are affected by melanoma-linked variants of the melanocortin 1 receptor (MC1R) gene. Read More

    Dermoscopic characterization of cutaneous lymphomas: a pilot survey.
    Int J Dermatol 2018 Jan 10. Epub 2018 Jan 10.
    Department of Dermatology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.
    Background: While substantial dermoscopic analysis of melanocytic lesions has been performed, dermoscopic characterization of cutaneous lymphoid proliferations has been limited. Cutaneous lymphoma, particularly early mycosis fungoides (MF) and its variants, is often challenging to clinically and pathologically distinguish from inflammatory processes of the skin. This study aimed to survey the dermoscopic findings of cutaneous lymphomas and to discern whether any patterns might potentially serve as specific signatures. Read More

    A Computer-Aided Decision Support System for Detection and Localization of Cutaneous Vasculature in Dermoscopy Images Via Deep Feature Learning.
    J Med Syst 2018 Jan 9;42(2):33. Epub 2018 Jan 9.
    Biomedical Engineering Program, University of British Columbia, Vancouver, BC, Canada.
    Vascular structures of skin are important biomarkers in diagnosis and assessment of cutaneous conditions. Presence and distribution of lesional vessels are associated with specific abnormalities. Therefore, detection and localization of cutaneous vessels provide critical information towards diagnosis and stage status of diseases. Read More

    Actinic Keratosis and Non-Invasive Diagnostic Techniques: An Update.
    Biomedicines 2018 Jan 8;6(1). Epub 2018 Jan 8.
    Clinica Dermatologica, Policlinico di Modena, Via del Pozzo 70, 41124 Modena, Italy.
    Actinic keratosis represents the earliest manifestation of non-melanoma skin cancer. Because of their risk of progression to invasive squamous cell carcinoma, an earlier diagnosis and treatment are mandatory. Their diagnosis sometimes could represent a challenge even for expert dermatologists. Read More

    The limitations of dermoscopy: false positive and false negative tumors.
    J Eur Acad Dermatol Venereol 2018 Jan 5. Epub 2018 Jan 5.
    First Department of Dermatology, Aristotle University, Thessaloniki, Greece.
    Dermoscopy has been documented to increase the diagnostic accuracy of clinicians evaluating skin tumors, improving their ability to detect skin cancer and better recognize benign moles. However, dermoscopically "false positive" and "false negative" tumors do exist. False positive diagnosis usually leads to unnecessary excisions. Read More

    Acral pigmented Spitz nevus in a child with transepidermal migration of melanocytes: Dermoscopic and reflectance confocal microscopic features.
    Pediatr Dermatol 2018 Jan 4. Epub 2018 Jan 4.
    Department of Dermatology, School of Medicine & Health Sciences, George Washington University, Washington, DC, USA.
    Acral pigmented Spitz nevi are seldom reported in the literature. We report a new case on the palm of a 4-year-old girl that demonstrated correlation between features observed on dermoscopy and reflectance confocal microscopy (RCM). Histopathology revealed a benign intraepidermal Spitz nevus with transepidermal elimination of melanocytes that showed on RCM as focal atypical bright cells concerning for malignancy. Read More

    Dermoscopy of arteriovenous tumour: A morphological study of 39 cases.
    Australas J Dermatol 2018 Jan 5. Epub 2018 Jan 5.
    Department of Dermatology, University Hospital of Alicante, Alicante, Spain.
    Background/objectives: Arteriovenous tumour is a distinct, benign, acquired vascular lesion that can be misdiagnosed.

    Methods: A dermoscopic examination of 39 cases of arteriovenous tumours collected from four Spanish hospitals was performed to evaluate specific dermoscopic criteria and patterns.

    Results: The most common structures found were vascular, 95% of cases (37/39); 90% (35/39) were non-arborising telangiectasia. Read More

    The association between dermoscopic features and BRAF mutational status in cutaneous melanoma: significance of the blue-white veil.
    J Am Acad Dermatol 2018 Jan 4. Epub 2018 Jan 4.
    Hospital Universitari i Politècnic La Fe [University and Polytechnic Hospital La Fe], València, Spain; Universitat de València [University of Valencia], València, Spain.
    Background: The genetic basis of melanoma affects its clinicopathological characteristics and increasingly influences its management. BRAF-mutated melanoma may present with specific dermoscopic features.

    Objectives: To identify the dermoscopic features associated with BRAF mutation in cutaneous melanoma and to evaluate a model capable of predicting BRAF mutations based on dermoscopic and clinicopathological features easily accessible in normal clinical practice. Read More

    A National Budget Impact Analysis of a Specialised Surveillance Programme for Individuals at Very High Risk of Melanoma in Australia.
    Appl Health Econ Health Policy 2018 Jan 5. Epub 2018 Jan 5.
    Sydney School of Public Health, The University of Sydney, The Lifehouse, Level 6-North, 119-143 Missenden Road, Camperdown, NSW, 2050, Australia.
    Background: Specialised surveillance using total body photography and digital dermoscopy to monitor people at very high risk of developing a second or subsequent melanoma has been reported as cost effective.

    Objectives: We aimed to estimate the 5-year healthcare budget impact of providing specialised surveillance for people at very high risk of subsequent melanoma from the perspective of the Australian healthcare system.

    Methods: A budget impact model was constructed to assess the costs of monitoring and potential savings compared with current routine care based on identification of patients at the time of a melanoma diagnosis. Read More

    Texture based skin lesion abruptness quantification to detect malignancy.
    BMC Bioinformatics 2017 Dec 28;18(Suppl 14):484. Epub 2017 Dec 28.
    Department of Computer Science, UCA, Conway, AR, 72034, USA.
    Background: Abruptness of pigment patterns at the periphery of a skin lesion is one of the most important dermoscopic features for detection of malignancy. In current clinical setting, abrupt cutoff of a skin lesion determined by an examination of a dermatologist. This process is subjective, nonquantitative, and error-prone. Read More

    Blue nevus with satellitosis: case report and literature review.
    An Bras Dermatol 2017 ;92(5 Suppl 1):30-33
    Private practice - Tubarão (SC), Brazil.
    Blue nevus is a benign melanocytic lesion, typically asymptomatic and of unknown etiology. Many histological subtypes are recognized, the most commons being: common blue nevus, cellular blue nevus, and combined blue nevus. New rare variants have been described in the literature, with emphasis on eruptive blue nevus, plaque, agminate, linear, with satellitosis, disseminated, familial and targetoid. Read More

    Comparison of computer systems and ranking criteria for automatic melanoma detection in dermoscopic images.
    PLoS One 2017 21;12(12):e0190112. Epub 2017 Dec 21.
    Department of Mathematics and Statistics, UiT The Arctic University of Norway, Tromsø, Norway.
    Melanoma is the deadliest form of skin cancer, and early detection is crucial for patient survival. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced. Read More

    [Unusual location of giant seborrhoeic keratoses].
    Pan Afr Med J 2017 25;28:72. Epub 2017 Sep 25.
    Service de Dermatologie et Vénérologie, Centre Hospitalier Universitaire IBN Sina, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Maroc.
    Seborrhoeic keratoses (SK) are benign tumors that mainly occur in the head and in the trunk. Their size generally varies from a few millimeters up to a few centimeters. Giant lesions are very rare but pose a problem in terms both of treatment and transformation. Read More

    Laugier-Hunziker syndrome: A case report.
    J Stomatol Oral Maxillofac Surg 2017 Dec 12. Epub 2017 Dec 12.
    Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, 210008 Nanjing, China. Electronic address:
    Laugier-Hunziker syndrome (LHS) is a rare, benign, acquired pigmentary condition mainly affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. Herein, we reported a 45-year-old female case with LHS. The clinical, dermoscopic, histopathologic features of LHS were reviewed and the important differential diagnosis was discussed. Read More

    Dermoscopy of Morphea and Cutaneous Lichen Sclerosus: Clinicopathological Correlation Study and Comparative Analysis.
    Dermatology 2017 Dec 14. Epub 2017 Dec 14.
    Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
    Background: Dermoscopy of morphea and cutaneous lichen sclerosus (CLS) has been described by various studies, with none of them considering variability according to clinical phases and investigating dermoscopic-histological correlations.

    Objective: To evaluate dermoscopic features in general and according to clinical stage, identify possible distinctive dermoscopic clues, and assess dermoscopy accuracy in detecting subclinical alterations in morphea and CLS.

    Methods: A representative dermoscopic image of target lesions was evaluated for the presence of specific features, correlating them with clinical subtype (inflammatory, inflammatory-sclerotic, sclerotic, or sclerotic-atrophic). Read More

    Dermoscopic features distinctive for extraocular sebaceous carcinoma.
    J Dermatol 2017 Dec 13. Epub 2017 Dec 13.
    Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan.
    We examined dermoscopic features of three cases of extraocular sebaceous carcinoma and reviewed the literatures. The yellowish structures, polymorphous vessels and ulceration were common findings in our cases and all cases of the previous reports. The appearance of whitish-pink areas has not been described previously. Read More

    Acral melanoma foot lesions. Part 2: clinical presentation, diagnosis, and management.
    Clin Exp Dermatol 2017 Dec 13. Epub 2017 Dec 13.
    Department of Dermatology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
    Acral melanoma (AM) is a rare subtype of cutaneous malignant melanoma found on acral skin, primarily on the soles of the feet. Although rare, it is the most common subtype of melanoma found in patients of African or Asian ethnicity and has a poor prognosis, often because of the more advanced stage of presentation at diagnosis. In the second of this two-part series, we review the clinical presentation, histopathology, diagnosis and management of AM. Read More

    Collision skin lesions-results of a multicenter study of the International Dermoscopy Society (IDS).
    Dermatol Pract Concept 2017 Oct 31;7(4):51-62. Epub 2017 Jul 31.
    Department of Dermatology, Medical University of Graz, Graz, Austria.
    Background: Collision lesions as two independent and unrelated skin tumors often manifest an atypical morphology.

    Objective: To determine the combinations of collision skin lesions (CSLs).

    Methods: Twenty-one pigmented lesion clinics in nine countries included 77 histopathologically proven CSLs in this retrospective observational study. Read More

    Reflectance Confocal Microscopy evaluation of Trichobacteriosis Axilaris.
    J Eur Acad Dermatol Venereol 2017 Dec 8. Epub 2017 Dec 8.
    Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.
    We read with great interest the paper by Navarrete-Dechent et al recently published on the Journal of European Academy of Dermatology1 , in which the authors detail the dermoscopic findings of trichobacteriosis and highlight the importance of dermoscopy in these cases. We present the case of a 44-year-old man, who emanated an unpleasant axilary odor during a routine check-up. Close examination of the axillary hair shafts showed soft, brown to yellow irregular masses adherent to the central segment of the hairs, suggesting the diagnosis of trichobacteriosis axilaris (TA). Read More

    Hypomelanotic melanoma detected by the "little red riding hood sign" in a patient with neurofibromatosis type 1.
    Dermatol Pract Concept 2017 Oct 15;7(4):71-73. Epub 2017 Jul 15.
    Department of Dermatology and Venereology, University of Trieste, Ospedale Maggiore, Trieste, Italy.
    Neurofibromatosis type 1 (NF1) is a genetic disorder commonly associated with an increased risk for development of malignancy, including skin cancers. Herein we describe a case of invasive melanoma occurring in a patient with NF1 and discuss the association between these two diseases, highlighting the importance of comparative clinical and dermoscopic approaches in this category of patients in which the detection of melanoma can be difficult because of the presence of multiple skin tumors. Read More

    Examining the factors associated with past and present dermoscopy use among family physicians.
    Dermatol Pract Concept 2017 Oct 31;7(4):63-70. Epub 2017 Oct 31.
    College of Osteopathic Medicine, Nova Southeastern University, Ft. Lauderdale, FL, USA.
    Introduction: Family physicians (FPs) play a critical role in the early detection of skin cancers. Dermoscopy can improve diagnostic accuracy but its use by FPs in the United States (US) remains understudied.

    Objectives: To examine dermoscopy use, factors associated with ever having used (Model 1) and currently using the dermascope (Model 2), and barriers. Read More

    A solitary pink lesion: dermoscopy and RCM features of lichen planus.
    Dermatol Pract Concept 2017 Oct 31;7(4):43-45. Epub 2017 Oct 31.
    Dermatology and Skin Cancer Unit, Arcispedale S. Maria Nuova, IRCCS, Reggio Emilia, Italy.
    We present an unusual onset of cutaneous lichen planus (LP) in a middle-aged patient. The initial presentation as solitary, indolent pink lesion required further investigations to rule out malignancy, especially amelanotic melanoma. Dermoscopy and reflectance confocal microscopy findings were found to be helpful in our case in addressing the correct diagnosis. Read More

    Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma.
    Dermatol Pract Concept 2017 Oct 31;7(4):39-42. Epub 2017 Oct 31.
    Department of Dermatology, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
    Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging of the skin. Read More

    Dermoscopy of chromoblastomycosis.
    Dermatol Pract Concept 2017 Oct 31;7(4):23-24. Epub 2017 Oct 31.
    Department of Dermatology and Venereology All India Institute of Medical Sciences, New Delhi, India.
    Chromoblastomycosis is a chronic cutaneous fungal infection commonly caused by Fonsacea and Cladophialophora spp. Dermoscopy is a non-invasive, real-time diagnostic tool for rapid bedside diagnosis of various inflammatory and non-inflammatory disorders and can be an excellent modality for evaluation of cutaneous mycosis, for which it shows characteristic brown dots, crust, scales and yellow orange structures. Read More

    White rosettes in discoid lupus erythematosus: a new dermoscopic observation.
    Dermatol Pract Concept 2017 Oct 31;7(4):9-11. Epub 2017 Oct 31.
    BLDE University's Shri M B Patil Medical College, Vijayapura, India.
    White rosettes are shiny white structures seen as four oval-shaped points that come together in the center. They resemble four-leaf clover [1]. Earlier it was thought they were specific for actinic keratosis and squamous cell carcinoma, but they are noted in many other conditions [2]. Read More

    Dermoscopic features and patterns of poromas: a multicentre observational case-control study conducted by the International Dermoscopy Society.
    J Eur Acad Dermatol Venereol 2017 Dec 1. Epub 2017 Dec 1.
    Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Background: Poromas are benign cutaneous sweat gland tumours that are challenging to identify. The dermoscopic features of poromas are not well characterized.

    Objective: To determine the clinical-dermoscopic features of poromas. Read More

    Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance.
    Br J Dermatol 2017 Nov 28. Epub 2017 Nov 28.
    General Hospital Augsburg, Department of Dermatology and Allergology, Augsburg, Germany.
    Background: We previously described the principal results from an observational, prospective, multi-centre, clinical trial of the diagnostic value of optical coherence tomography (OCT) for basal cell carcinoma (BCC) in a clinical setting. In this trial, much additional useful information was gathered that warranted further analysis, presented here.

    Objectives: To investigate the influence of candidate diagnostic criteria, OCT image quality, lesion location, and observer confidence and inter-observer variability on the diagnostic performance, and to assess potential for diagnosis of BCC subtypes. Read More

    Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma.
    An Bras Dermatol 2017 May-Jun;92(3):375-378
    Department of Pathology - School of Medicine at Universidade Federal do Rio de Janeiro (UFRJ) - Rio de Janeiro (RJ), Brazil.
    The concern about malignant skin neoplasms leads to the excision of smaller lesions. This study on small melanocytic lesions aims to evaluate the range of possible histopathological diagnoses, describe histopathological aspects, and assess the usefulness of serial histological sections. We performed a cross-sectional descriptive histopathological study examining 76 pigmented skin lesions up to 6 mm in diameter. Read More

    Dermoscopic patterns of melanocytic nevi in children and adolescents: a cross-sectional study.
    An Bras Dermatol 2017 May-Jun;92(3):340-344
    Dermatology Outpatient Clinic of the Universidade Federal de São Paulo (EPM-UNIFESP) - São Paulo (SP), Brazil.
    Background: Childhood is a dynamic period regarding nevogenesis. Dermoscopy is a noninvasive technique, recommended for the evaluation of pigmented cutaneous lesions.

    Objectives: The purpose of this study was to describe the structures and dermoscopic patterns of melanocytic nevi observed in children and adolescents. Read More

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