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    Onychophagia Induced Melanonychia, Splinter Hemorrhages, Leukonychia, and Pterygium Inversum Unguis Concurrently.
    Case Rep Dermatol Med 2018 30;2018:3230582. Epub 2018 Jan 30.
    Department of Dermatology, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey.
    Onychophagia, which refers to compulsive nail-biting behavior, is common among children and young adults. Onychophagia can cause destruction to the cuticle and nail plate, leading to shortening of nails, chronic paronychia, and secondary infections. Relatively uncommon effects include pigmentary changes, such as longitudinal melanonychia and splinter hemorrhages. Read More

    Dermoscopic features of onychotillomania: A study of 36 cases.
    J Am Acad Dermatol 2018 Apr 13. Epub 2018 Apr 13.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
    Background: Onychotillomania is a nail-picking disorder characterized by nail dystrophy and abnormal morphology of the nail plate, nail bed, and periungual skin.

    Objective: The purpose of this study was to describe the dermoscopic features of onychotillomania.

    Methods: A retrospective study of the dermoscopy images of 36 patients affected by onychotillomania. Read More

    Dermoscopy in the Diagnosis of Inflammatory Dermatoses: Systematic Review Findings Reported for Psoriasis, Lupus, and Lichen Planus.
    J Clin Aesthet Dermatol 2018 Apr 1;11(4):41-42. Epub 2018 Apr 1.
    Drs. Cook, Foulke, and Seiverling are with the Department of Dermatology.
    Dermoscopy is well established as a tool to improve the detection of cancerous skin growths. Published data suggest that dermoscopy might be useful in evaluating inflammatory dermatoses and in distinguishing between rashes and skin cancer. The authors sought to review the published literature regarding use of dermoscopy in the evaluation of inflammatory skin conditions. Read More

    Dermoscopy in the diagnosis of juvenile xanthogranuloma.
    An Bras Dermatol 2018 Jan-Feb;93(1):138-140
    Dermatology Department at Hospital Santa Casa de Curitiba - Curitiba (PR), Brazil.
    Juvenile xanthogranuloma is the most common form of non-Langerhans cell histiocytosis. It manifests clinically as a red-yellow papule, usually showing spontaneous remission. The diagnosis is based on clinical and histological findings. Read More

    Periungual basal cell carcinoma.
    An Bras Dermatol 2018 Jan-Feb;93(1):114-115
    Dermatology Service at Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.
    Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit can shorten the diagnostic process and avoid destructive treatment and functional damage. Read More

    Application of dermoscopy image analysis technique in diagnosing urethral condylomata acuminata.
    An Bras Dermatol 2018 Jan-Feb;93(1):67-71
    Department of Dermatology of First Affiliated Hospital of PLA General Hospital - Beijing, China.
    Background: In this study, cases with suspected urethral condylomata acuminata were examined by dermoscopy, in order to explore an effective method for clinical.

    Objective: To study the application of dermoscopy image analysis technique in clinical diagnosis of urethral condylomata acuminata.

    Methods: A total of 220 suspected urethral condylomata acuminata were clinically diagnosed first with the naked eyes, and then by using dermoscopy image analysis technique. Read More

    Acrokeratoelastoidosis of the Foot with Clinical, Dermoscopic, Ultrasonographic, and Histopathologic Correlation.
    J Am Podiatr Med Assoc 2018 Mar;108(2):178-181
    Acrokeratoelastoidosis (AKE) is a rare form of focal acral keratoderma of unknown cause that typically begins during childhood and manifests with multiple, small, hyperkeratotic papules located over the lateral margins of the hands and feet. The purpose of this article is to report a pediatric case of AKE with dermoscopic, sonographic, and histopathologic descriptions, contributing to the awareness of this clinical diagnosis. We describe a 7-year-old girl with nonpainful yellowish papules on the lateral and medial aspects of both feet. Read More

    Accuracy of dermoscopic criteria for the differentiation between superficial basal cell carcinoma and Bowen's disease.
    J Eur Acad Dermatol Venereol 2018 Apr 6. Epub 2018 Apr 6.
    First Department of Dermatology, Aristotle University, Thessaloniki, Greece.
    Background: The dermoscopic features of superficial basal cell carcinoma (sBCC) and Bowen's disease (BD) have been extensively investigated and dermoscopy was shown to significantly improve their recognition. However, incorrectly diagnosed cases still exist, with a considerable number of sBCCs dermoscopically interpreted as BD. Our aim was to investigate the dermoscopic variability of sBCC and BD on different anatomic sites, to identify potent dermoscopic predictors for each diagnosis and to investigate the potential source of the inaccurate clinico-dermoscopic diagnosis of some sBCCs. Read More

    Clinical and dermoscopic characteristics of congenital melanocytic nevi.
    J Eur Acad Dermatol Venereol 2018 Apr 6. Epub 2018 Apr 6.
    1st Department of Dermatology - Venereology, "Andreas Sygros" University Hospital, Athens, Greece.
    Material And Methods: All children with congenital nevi (CN) attending our Pediatric Pigmented Skin lesion Unit during a 2 year period were included in the study. Clinical data were collected and all children underwent clinical and dermoscopic examination. Dermoscopic patterns and specific features were recorded. Read More

    Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy.
    F1000Res 2018 6;7:284. Epub 2018 Mar 6.
    Department of Dermatology, College of Medicine, King Faisal University, Hofuf, Saudi Arabia.
    Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham's striae constituting the hallmark of the condition. Read More

    The efficacy of a nested PCR in detecting cytochrome c oxidase subunit 1 gene of Sarcoptes scabiei var. Hominis for diagnosing scabies.
    Br J Dermatol 2018 Apr 6. Epub 2018 Apr 6.
    Department of Dermatology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
    Background: A widespread scabies infestation, associated to long-term residence in nursing homes, is becoming a serious issue in developed countries. Mineral oil examination is regarded as the gold standard in diagnosing scabies, but the sensitivity of this method is generally low-approximately 50%. Molecular tests may contribute to enhance the sensitivity of current tests for laboratory diagnosis of human scabies. Read More

    An Image Processing and Genetic Algorithm-based Approach for the Detection of Melanoma in Patients.
    Methods Inf Med 2018 02 5;57(1):74-80. Epub 2018 Apr 5.
    Melanoma skin cancer is the most aggressive type of skin cancer. It is most commonly caused by excessive exposure to Ultraviolet radiation which triggers uncontrollable proliferation of melanocytes. Early detection makes melanoma relatively easily curable. Read More

    A new dermoscopic algorithm for the differential diagnosis of facial lentigo maligna and pigmented actinic keratosis.
    Eur J Dermatol 2018 Apr 5. Epub 2018 Apr 5.
    Institute of Dermatology, Catholic University of Rome, Rome, Italy.
    The clinical and dermoscopic diagnosis of facial lentigo maligna (LM) and pigmented actinic keratosis (PAK) remains challenging, particularly at the early disease stages. To identify dermoscopic criteria that might be useful to differentiate LM from PAK, and to elaborate and validate an automated diagnostic algorithm for facial LM/PAK. We performed a retrospective multicentre study to evaluate dermoscopic images of histologically-proven LM and PAK, and assess previously described dermoscopic criteria. Read More

    Recognition of early melanoma: a monocentric dermoscopy follow-up study comparing de novo melanoma with nevus-associated melanoma.
    Int J Dermatol 2018 Apr 2. Epub 2018 Apr 2.
    Division of Dermatology and Venereology, University Hospital of Geneva, Geneva, Switzerland.
    Background: The earlier detection of melanomas occurring within preexisting nevi is theoretically possible using sequential dermoscopy. Characterizing the early follow-up changes of nevus-associated melanomas (NAMs) and differentiating them from those observed in de novo melanomas (DNMs) may help the earlier recognition of NAMs.

    Methods: Using descriptive dermoscopic features to detect focal changes, we blindly evaluated retrospectively the baseline and follow-up images of 32 melanomas that were subsequently classified as histopathologically defined NAMs or DNMs. Read More

    A novel heterozygous missense mutation of DSP in a Chinese Han pedigree with palmoplantar keratoderma.
    J Cosmet Dermatol 2018 Apr 1. Epub 2018 Apr 1.
    Department of Dermatology, China-Japan Friendship Hospital, Beijing, China.
    Background: Mutations in the desmoplakin (DSP) gene have been demonstrated to be associated with lethal acantholytic epidermolysis bullosa, cardiomyopathy, and palmoplantar keratoderma (PPK).

    Aims: To better understand the relationship between PPK and the gene mutations in DSP.

    Methods: A pedigree of PPK was subjected to heterozygous missense mutation analysis in the DSP gene. Read More

    Clinical and dermoscopic response predictors in psoriatic patients undergoing narrowband ultraviolet B phototherapy: results from a prospective study.
    Int J Dermatol 2018 Mar 31. Epub 2018 Mar 31.
    Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
    Background: Although disease severity, gender, body weight, and previous treatments have all been reported to affect clinical response of psoriasis vulgaris to narrowband ultraviolet B (NB-UVB) therapy, little information about possible local (lesional) influencing factors is available.

    Objective: To assess correlations between clinical/dermoscopic findings of psoriatic plaques and therapeutic response to NB-UVB phototherapy in order to find positive and/or negative response predictor factors to such a treatment.

    Methods: For each target lesion, we calculated local psoriasis severity index and assessed dermoscopic findings at the baseline. Read More

    Dermoscopic assessment of skin toxicities in patients with melanoma during treatment with vemurafenib.
    Postepy Dermatol Alergol 2018 Feb 20;35(1):39-46. Epub 2018 Feb 20.
    Department of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Poland.
    Introduction: The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities.

    Aim: To assess skin toxicities by dermoscopy in patients treated with vemurafenib.

    Material And Methods: Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. Read More

    Utility of dermoscopy for evaluating the therapeutic efficacy of tacrolimus ointment plus 308-nm excimer laser combination therapy in localized vitiligo patients.
    Exp Ther Med 2018 Apr 28;15(4):3981-3988. Epub 2018 Feb 28.
    Department of Dermatology, Dong Guan People's Hospital, Dongguan, Guangdong 523018, P.R. China.
    The aim of the present study was to assess the function of dermoscopy in evaluating the therapeutic efficacy of tacrolimus ointment plus 308-nm excimer laser combination therapy in patients with localized vitiligo. A total of 147 patients with localized vitiligo (progressive disease, n=92; stable period, n=55) were enrolled and received combination therapy for 12 weeks. The condition of the skin lesions was monitored by dermoscopy and visual observation. Read More

    An atypical clinical presentation of lichen planus pigmentosus with typical dermoscopic pattern.
    Australas J Dermatol 2018 Mar 25. Epub 2018 Mar 25.
    Department of Dermatology, Sir T Hospital, Government Medical College, Bhavnagar, Gujarat, India.
    We report a rare and interesting case of a combined linear, Blaschkoid and zosteriform pattern of lichen planus pigmentosus. Dermoscopy showed discrete bluish-grey dots, globules, blotches and rods against a brownish background. A skin biopsy confirmed the diagnosis from the presence of civatte bodies, melanin incontinence and band-like inflammation. Read More

    Prevalence of Nail Scabies: A French Prospective Multicenter Study.
    J Pediatr 2018 Mar 23. Epub 2018 Mar 23.
    University François Rabelais Tours, Faculty of Medicine, Tours, France; Department of Dermatology, Unit of Paediatric Dermatology, Centre Hospitalier Régional et Universitaire Tours, Tours, France. Electronic address:
    Introduction: To assess the prevalence of nail involvement in children <16 years old with a confirmed diagnosis of scabies.

    Study Design: Observational, prospective study in 7 French dermatology departments between June 2015 and January 2017. Children were included if they had scabies confirmed by dermoscopy and/or microscopy and if nails could be sampled. Read More

    The diagnosis and management of extramammary Paget's disease.
    Expert Rev Anticancer Ther 2018 Mar 27:1-11. Epub 2018 Mar 27.
    a Department of Dermatology, Graduate School of Medical Sciences , Kyushu University , Fukuoka , Japan.
    Introduction: Extramammary Paget's disease (EMPD) is a rare neoplastic condition that commonly affects the anogenital area in the elderly. Owing to its low incidence, limited data regarding EMPD's diagnosis and treatment have been available. This review article aims to explore the current knowledge of EMPD to improve the management of this disease. Read More

    OCT image atlas of healthy skin on sun-exposed areas.
    Skin Res Technol 2018 Mar 25. Epub 2018 Mar 25.
    Wayne State University School of Medicine, Detroit, MI, USA.
    Background: Skin cancer represents the most prevalent type of cancer in the United States. Excision of these lesions can leave significant scarring, and a delay in the diagnosis of malignant melanoma could result in metastasis or death. Therefore, developing technology and criteria to accurately diagnose these cancers is of particular importance to the medical community. Read More

    Assessing hyperthermia-induced vasodilation in human skin in vivo using optoacoustic mesoscopy.
    J Biophotonics 2018 Mar 23:e201700359. Epub 2018 Mar 23.
    Technische Universität München, Chair of Biological Imaging, Ismaninger Straße 22, Munich, Germany.
    The aim of this study was to explore the unique imaging abilities of optoacoustic mesoscopy to visualize skin structures and microvasculature with the view of establishing a robust approach for monitoring heat-induced hyperemia in human skin in vivo. Using raster-scan optoacoustic mesoscopy (RSOM), we investigated whether optoacoustic (photoacoustic) mesoscopy can identify changes in skin response to local heating at microvasculature resolution in a cross-sectional fashion through skin in the human forearm. We visualized the heat-induced hyperemia for the first time with single-vessel resolution throughout the whole skin depth. Read More

    Dermoscopy features of atypical fibroxanthoma: A multicenter study of the International Dermoscopy Society.
    Australas J Dermatol 2018 Mar 23. Epub 2018 Mar 23.
    Dermatology Unit, University of Campania Luigi Vanvitelli, Naples, Italy.
    Background/objectives: Little is known about the dermoscopic features of atypical fibroxanthoma.

    Methods: This was a case-control study. Atypical fibroxanthoma lesions were compared with a control group with non-melanoma skin cancer. Read More

    Trichoscopy of alopecia areata: An update.
    J Dermatol 2018 Mar 22. Epub 2018 Mar 22.
    Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
    The diagnosis of alopecia areata is usually based on clinical manifestations. However, there are several hair and scalp disorders that share similar clinical features with alopecia areata, such as tinea capitis, trichotillomania or traction alopecia. Trichoscopy as a fast, non-invasive and easy-to-perform technique may help to identify subtle details and establish the correct diagnosis. Read More

    Diagnostic accuracy of dermatofluoroscopy in cutaneous melanoma detection: Results of a prospective multicentre clinical study in 476 pigmented lesions.
    Br J Dermatol 2018 Mar 22. Epub 2018 Mar 22.
    Department of Dermatology, University of Heidelberg, Germany.
    Background: Early detection is a key factor in improving survival from melanoma. Today, the clinical diagnosis of cutaneous melanoma is mostly based on visual inspection and dermoscopy. Preclinical studies in freshly excised or paraffin-embedded tissue have shown that the melanin fluorescence spectra after stepwise two-photon excitation, a process termed dermatofluoroscopy, differ between cutaneous melanoma and melanocytic nevi. Read More

    Clinical and dermoscopic features of Spitz nevus by sex, age and anatomical site: a study of 913 Spitz naevi.
    Br J Dermatol 2018 Mar 22. Epub 2018 Mar 22.
    Section of Dermatology Department of Clinical Medicine and Surgery Dermatology Unit, University of Naples Federico II, Italy.
    Spitz nevus is a benign melanocytic proliferation, typified on dermoscopy by the so-called "starburst pattern", characterized by peripheral streaks or pseudopods, symmetrically distributed. It occurs in both children and adults. According to the literature, it has been previously reported a difference in the dermoscopic features of Spitz naevi by age and anatomical site. Read More

    Dermoscopic Features of Basal Cell Carcinoma on the Lower Limbs: A Chameleon!
    Dermatology 2017 22;233(6):482-488. Epub 2018 Mar 22.
    Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
    Background: Lower limbs represent an uncommon location for basal cell carcinoma (BCC) and only few reports have described dermoscopic features of BCC in this body site. Since BCCs of the lower limbs frequently display nonclassic BCC dermoscopic criteria, they can simulate other benign or malignant lesions.

    Objective: Our aim was to describe the dermoscopic features of BCC located on lower limbs and to define which criteria were more associated with their benign- or malignant-looking appearance. Read More

    Clinical, dermoscopic and trichoscopic analysis of frontal fibrosing alopecia associated with acquired dermal macular hyperpigmentation: A cross sectional observational case-control study.
    J Am Acad Dermatol 2018 Mar 12. Epub 2018 Mar 12.
    Department of Dermatology, Venereology and Leprology; Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address:

    Scaly pink patches: differentiating psoriasis from basal cell carcinoma.
    Cutis 2018 Jan;101(1):44-46
    Department of Family and Community Medicine, Department of Dermatology, Penn State Milton S. Hershey Medical Center, USA.
    Dermoscopy, commonly used to analyze skin tumors, has more recently been used to evaluate inflammatory dermatoses. We performed a systematic review of the literature to assess the role of dermoscopy in evaluating psoriasis, and briefly reviewed the findings with an emphasis on the specificity or sensitivity of the dermoscopic findings of psoriasis. We also describe the case of a 63-year-old man with a history of psoriasis and basal cell carcinoma (BCC) who presented with a new scaly pink patch on the back. Read More

    A Multicenter Survey: How Do Transplant Dermatologists Monitor Organ Transplant Recipients With Nevi?
    Exp Clin Transplant 2018 Mar;16(Suppl 1):198-202
    Department of Dermatology, Baskent University Faculty of Medicine, Ankara, Turkey.
    Objectives: The incidence and mortality of melanoma are increased in organ transplant recipients. Multiple acquired common and dysplastic nevi are risk factors for melanoma. A new or changing nevus may suggest melanoma. Read More

    Acral melanoma detection using a convolutional neural network for dermoscopy images.
    PLoS One 2018 7;13(3):e0193321. Epub 2018 Mar 7.
    Department of Dermatology, Keimyung University, College of Medicine, Daegu, Republic of Korea.
    Background/purpose: Acral melanoma is the most common type of melanoma in Asians, and usually results in a poor prognosis due to late diagnosis. We applied a convolutional neural network to dermoscopy images of acral melanoma and benign nevi on the hands and feet and evaluated its usefulness for the early diagnosis of these conditions.

    Methods: A total of 724 dermoscopy images comprising acral melanoma (350 images from 81 patients) and benign nevi (374 images from 194 patients), and confirmed by histopathological examination, were analyzed in this study. Read More

    Acral melanoma: correlating the clinical presentation to the mutational status.
    G Ital Dermatol Venereol 2018 Mar 6. Epub 2018 Mar 6.
    Dermatology Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
    Acral lentiginous melanoma (ALM) is the most common type of malignant melanoma (MM) in Asians, Afro-Americans and Middle-Easterns. It represents 1.5-10% of all MM cases, being the most common histological type of MM arising on palms, soles and nail apparatus, which is more generically defined as acral MM. Read More

    Dermoscopy Improves the Diagnostic Accuracy of Melanomas Clinically Resembling Seborrheic Keratosis: Cross-Sectional Study of the Ability to Detect Seborrheic Keratosis-Like Melanomas by a Group of Dermatologists with Varying Degrees of Experience.
    Dermatology 2017 2;233(6):471-479. Epub 2018 Mar 2.
    Dermatology Clinic, Hospital Maggiore, University of Trieste, Trieste, Italy.
    Background: Malignant melanomas mimicking seborrheic keratosis (SK-like MMs) carry the risk of delayed diagnosis and inadequate treatment. The value of dermoscopy to improve the correct detection of these mimickers has not been previously studied.

    Objective: To evaluate the diagnostic accuracy of clinically SK-like MMs with and without dermoscopy. Read More

    Pediatric melanoma update.
    G Ital Dermatol Venereol 2018 Feb 26. Epub 2018 Feb 26.
    Harvard Medical School, Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA -
    Pediatric melanoma is a rare disease that affects approximately 6 out of every one million children and accounts for 1-4 percent of all melanomas. This article reviews the epidemiology, etiology, diagnosis, treatment and prognosis of pediatric melanoma - with particular attention to recent updates in the literature. While awareness of melanoma increases among the general population, recent data suggest stable and even declining incidence rates among certain pediatric populations. Read More

    Small Dysplastic Congenital Melanocytic Nevi in Childhood as Possible Melanoma Imitators.
    Open Access Maced J Med Sci 2018 Jan 13;6(1):149-151. Epub 2018 Jan 13.
    "Onkoderma"- Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
    Small pigmented lesions in children can represent a significant diagnostic challenge. If the diagnostic features and therapeutic approach are relatively well established in large and giant nevi, there is still much controversy regarding small and intermediate-sized congenital pigmented lesions that can lead to significant diagnostic challenges, both clinically and dermoscopically, and consequently to difficulty in defining the optimal approach in such cases. Although dermoscopy can be useful in the diagnosis of pigmented lesions, the diversity of clinical and dermoscopic features of pigmented nevi in children usually hinder the differentiation between them and melanoma. Read More

    A "Yellow Submarine" in Dermoscopy.
    Open Access Maced J Med Sci 2018 Jan 7;6(1):76-78. Epub 2018 Jan 7.
    University of Rome G. Marconi, Rome 00186, Institute of Dermatology, Italy.
    Background: Histiocytic sarcoma (HS) is an extremely rare, non-Langerhans cell tumor. HS affects especially adults, its etiology is unknown yet. Skin could be interested by papules or nodules, single or multiple. Read More

    Subungual Exostosis in a Young Soccer Player.
    Open Access Maced J Med Sci 2018 Jan 30;6(1):52-54. Epub 2017 Dec 30.
    Medical Institute of the Ministry of Interior, Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.
    Background: Subungual exostosis is a relatively uncommon, benign osteocartilaginous tumor of the distal phalanx of the toes or fingers in young adults, considered as a rare variant of osteochondroma. Differential diagnoses include subungual verruca (viral wart), pyogenic granuloma, osteochondroma, amelanotic subungual melanoma and glomus tumour. Misdiagnosis and total onychodystrophy frequently occur as a result of late treatment or inadequate treatment strategy. Read More

    Erythematous asymptomatic nodule on the sole.
    Dermatol Online J 2017 Oct 15;23(10). Epub 2017 Oct 15.
    Department of Dermatology, Hospital Universitari Sagrat Cor, Barcelona, Spain.
    A 75-year-old man presented to the dermatology clinic with an asymptomatic lesion on his right plantar surface. The lesion had progressively grown for two months. Physical examination revealed an erythematous and slightly scaly nodule measuring 10x10 mm. Read More

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