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Dermatol Ther 2020 Jun 29:e13925. Epub 2020 Jun 29.

Department of Dermatovenereology, West China Hospital of Sichuan University.

Cureus 2020 May 25;12(5):e8272. Epub 2020 May 25.

Dermatology, State University of New York Downstate Medical Center, Brooklyn, USA.

Trichoblastoma is a rare, slow-growing, benign cutaneous tumor derived from follicular germinative cells. Trichoblastoma commonly appears as an asymptomatic, symmetrical, well-circumscribed, skin-colored to brown or blue-black papule or nodule. It may appear clinically and histologically similar to basal cell carcinoma, making its diagnosis challenging. Read More

J Am Acad Dermatol 2020 Jun 24. Epub 2020 Jun 24.

Dermatology Unit, University of Campania Luigi Vanvitelli, Naples, Italy.

Background: A recently introduced dermatoscopic method for diagnosis of early lentigo maligna (LM) is based on the absence of prevalent patterns of pigmented actinic keratosis (PAK) and solar lentigo/flat seborrheic keratosis (SL/SK). We term this the "inverse approach" OBJECTIVE: To determine whether training on the inverse approach increases the diagnostic accuracy of readers as compared to classic pattern analysis.

Methods: We used clinical and dermatoscopic images of histopathologically diagnosed LMs, PAKs and SLs/SKs. Read More

Skin Res Technol 2020 Jun 25. Epub 2020 Jun 25.

Department of Dermatology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.

Background: The diagnosis of actinic keratosis (AK) is based on clinical evaluation and confirmed by histopathological analysis (HA). The challenge is to establish the correct diagnosis with a minimally invasive assessment. The aim of this study is to validate the analysis of AK by reflectance confocal microscopy (RCM), a cellular resolution, noninvasive imaging method and to determine the relevant parameters for diagnosis, compared to HA, by calculating the sensitivity (S), specificity (E), positive predictive value (PPV), and negative predictive value (NPV) of each criterion. Read More

Lasers Med Sci 2020 Jun 25. Epub 2020 Jun 25.

Dermatology Department, Ramon y Cajal University Hospital, Carretera Colmenar Viejo km 9.100, 28034, Madrid, Spain.

J Biomed Opt 2020 Jun;25(6):1-21

Wyant College of Optical Sciences, The Univ. of Arizona, United States.

Significance: The rates of melanoma and nonmelanoma skin cancer are rising across the globe. Due to a shortage of board-certified dermatologists, the burden of dermal lesion screening and erythema monitoring has fallen to primary care physicians (PCPs). An adjunctive device for lesion screening and erythema monitoring would be beneficial because PCPs are not typically extensively trained in dermatological care. Read More

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Dermatology, Waikato Hospital, Waikato District Health Board, Hamilton, New Zealand.

Background/objectives: Basal cell carcinoma (BCC) is the most commonly occurring skin cancer. BCCs have been found to generally grow slowly. Data are limited on how the dermoscopic characteristics of BCCs evolve. Read More

Clin Case Rep 2020 Jun 24;8(6):1007-1009. Epub 2020 Mar 24.

Division of Dermatological Science Department of Dermatology Nihon University School of Medicine Tokyo Japan.

Spitz nevus is an important differential diagnosis of malignant melanoma, especially in young adults. This case provides a significant information about unusual dermoscopic features of adult Spitz nevus, which may reflect changes over the years. Read More

Clin Exp Dermatol 2020 Jun 22. Epub 2020 Jun 22.

Centre Hospitalier de Lyon Sud, Université Claude Bernard Lyon, Centre de recherche sur le cancer de Lyon, Lyon, France.

Background: Subungual squamous cell carcinoma (SU-SCC) is the most common malignant tumor of the nail unit. Intraoperative nail dermoscopy has only been described for pigmented tumors, onychomatricoma and glomus tumors.

Aims: Description of intraoperative dermoscopy features of SU-SCC. Read More

Acta Dermatovenerol Alp Pannonica Adriat 2020 Jun;29(2):81-83

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Riehl melanosis (RM) is a form of pigmented contact dermatitis that often poses a diagnostic challenge due to overlaps in its clinical, dermoscopic, and histopathological features with other pigmentary disorders. This report highlights significant findings and the proper approach for diagnosis. We present the case of a 47-year-old female with progressive facial hyperpigmentation (irregular, blotchy, grayish patches on the forehead, cheeks, and around the mouth) that acknowledged applying a lightening product before her complaint. Read More

Indian J Dermatol 2020 May-Jun;65(3):232-234

Department of Dermatology, Government Medical College, Srinagar, Jammu and Kashmir, India. E-mail:

Pigment Cell Melanoma Res 2020 Jun 18. Epub 2020 Jun 18.

Department of Dermatology, University of California, San Francisco, CA, USA.

Melanoma presents challenges for timely and accurate diagnosis. Expert panels have issued risk-based screening guidelines, with recommended screening by visual inspection. To assess how recent technology can impact the risk/benefit considerations for melanoma screening, we comprehensively reviewed noninvasive visual-based technologies. Read More

Eur J Dermatol 2020 Jun 15. Epub 2020 Jun 15.

Department of Dermatology, Asahikawa Medical University, Asahikawa, Japan.

J Am Acad Dermatol 2020 Jun 14. Epub 2020 Jun 14.

Indira Gandhi Government Medical College, Nagpur, India. Electronic address:

Int J Trichology 2020 Jan-Feb;12(1):24-28. Epub 2020 Apr 9.

Department of Dermatology, Venereology and Leprology, Seth G. S. Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India.

Background: Dermoscopy is a noninvasive tool for the diagnosis of various dermatological disorders. Dermoscopy of alopecia areata (AA) aids in confirming the diagnosis and severity of the disease.

Materials And Methods: A total of 100 patients of AA were evaluated with a dermoscope (×20 and × 200) to determine the dermoscopic features at the center and periphery of patches of AA. Read More

J Dermatolog Treat 2020 Jun 26:1-7. Epub 2020 Jun 26.

Department of Dermatology, Venereology and Andrology, Faculty of Human Medicine, Zagazig University, Zagazig, Egypt.

Recalcitrant plantar warts are representing a therapeutic challenge. Intralesional cryotherapy (ILC) has emerged as a promising therapeutic option in recalcitrant plantar warts treatment.: To compare the clinical efficacy, safety and tolerability of (ILC) versus Cryotherapy spray (Cryo-sp) for treatment of recalcitrant plantar warts. Read More

J Dermatol 2020 Jun 14. Epub 2020 Jun 14.

Dermatology Department, Hospital Sant Pau i Santa Tecla, Tarragona, Spain.

Polarized dermoscopy enables visualization of linear shiny white structures in melanomas, thought to be due to the existence of fibrosis in the dermis. Our objective was to establish the existence of two types of linear shiny white structures and assess their association with different histological structures. We performed a cross-sectional study including all non-acral, non-facial melanomas from our hospital with linear shiny white structures. Read More

Eur J Cancer 2020 Jun 10;135:39-46. Epub 2020 Jun 10.

Department of Dermatology, University of Heidelberg, Heidelberg, Germany. Electronic address:

Background: Convolutional neural networks (CNNs) have shown a dermatologist-level performance in the classification of skin lesions. We aimed to deliver a head-to-head comparison of a conventional image analyser (CIA), which depends on segmentation and weighting of handcrafted features, to a CNN trained by deep learning.

Methods: Cross-sectional study using a real-world, prospectively acquired, dermoscopic dataset of 1981 skin lesions to compare the diagnostic performance of a market-approved CNN (Moleanalyzer-Pro™, developed in 2018) to a CIA (Moleanalyzer-3™/Dynamole™; developed in 2004, all FotoFinder Systems Inc, Germany). Read More

J Am Acad Dermatol 2020 Jun 10. Epub 2020 Jun 10.

Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.

Background: Nevus phenotype is a marker of melanoma risk. In-vivo prediction of microscopic pattern is needed to more precisely classify nevi.

Objective: To identify dermoscopic and clinical predictors of microscopic patterns of typical nevi. Read More

Dermatol Ther (Heidelb) 2020 Jun 12. Epub 2020 Jun 12.

Department of Medical Area, Institute of Dermatology, University of Udine, Udine, UD, Italy.

Introduction: Little information on possible local factors that can influence the achievement and retention of response of plaque-type psoriasis to calcipotriene plus betamethasone dipropionate aerosol foam is available. The aim of this study was to assess possible correlations between baseline clinical/dermoscopic features of psoriatic plaques and therapeutic response, and between residual dermoscopic findings in clinically improved/healed lesions and post-treatment relapse.

Methods: For each target lesion, we calculated the local psoriasis severity index and assessed dermoscopic findings at baseline and at the end of a 4-week treatment, correlating the therapeutic outcome with the initial clinical and dermoscopic features. Read More

Dermatol Ther (Heidelb) 2020 Jun 12. Epub 2020 Jun 12.

Department of Dermatology, University of Brescia, ASST Spedali Civili of Brescia, Brescia, Italy.

Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare variant of lichen planopilaris, characterized by a triad of clinical signs including follicular spinous papules on the body area, scarring alopecia of the scalp and non-scarring alopecia of the groin and/or axilla. To date, fewer than 50 cases have been described in the literature. We first report a case of GLPLS investigated with non-invasive techniques such as dermoscopy and in vivo reflectance confocal microscopy (RCM) and successfully treated with narrowband-UVB (NB-UVB) phototherapy. Read More

J Eur Acad Dermatol Venereol 2020 Jun 12. Epub 2020 Jun 12.

Dermatology Clinic, University of Catania, Catania, Italy.

The male and female external genital regions are anatomical areas in which various types of skin disorders may occur. Although most of these conditions can be diagnosed by means of clinical examination accurate and medical history, in most cases further investigations with time consuming and/or invasive procedures are needed in order to reach the correct diagnosis. Dermoscopy, as a modern non-invasive tool, is able to better diagnose pigmented and non-pigmented skin tumours along with various inflammatory and infectious skin and appendage disorders. Read More

Cureus 2020 May 7;12(5):e8012. Epub 2020 May 7.

Dermatology, University of Texas McGovern Medical School, Houston, USA.

Eccrine hidrocystomas are benign, cystic tumors that are most commonly found on the central face in middle-aged females. Their dermoscopic findings are rarely described in the literature, with only seven cases currently reported to date. We present the case of an elderly man with an unusual location of an eccrine hidrocystoma of the central chest and its associated dermoscopic findings. Read More

Comput Methods Programs Biomed 2020 May 29;195:105568. Epub 2020 May 29.

The State key laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

Background And Objective: There are many types of skin cancer, and melanoma is the most lethal one. Dermoscopy is an important imaging technique to screen melanoma and other skin lesions. However, Skin lesion classification based on computer-aided diagnostic techniques is a challenging task owing to the scarcity of labeled data and class-imbalanced dataset. Read More

PLoS One 2020 11;15(6):e0234334. Epub 2020 Jun 11.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: Onychomycosis is the most common nail disorder and is associated with diagnostic challenges. Emerging non-invasive, real-time techniques such as dermoscopy and deep convolutional neural networks have been proposed for the diagnosis of this condition. However, comparative studies of the two tools in the diagnosis of onychomycosis have not previously been conducted. Read More

J Pediatr 2020 Jun 7. Epub 2020 Jun 7.

Medstar Washington Hospital Center/Georgetown University. Electronic address:

An Bras Dermatol 2020 May 11. Epub 2020 May 11.

Outpatient Clinic of Capillary Disorders, Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa de Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Dissecting cellulitis is a chronic, progressive, and relapsing inflammatory disease that predominantly affects the vertex and occiput of young Afro-descendent men. Itstarts with papules and pustules that evolves to nodules, abscesses, and cicatricial alopecia. This article illustrates the evolutive trichoscopy of dissecting cellulitis, from its early phase, through the abscess phase, to the fibrotic cicatricial phase. Read More

Case Rep Dermatol 2020 May-Aug;12(2):98-106. Epub 2020 May 15.

Department of Medicine and Medical Specialties, University of Alcalá, Madrid, Spain.

Pigmented Bowen's disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. Read More

Acta Derm Venereol 2020 Jun 18;100(13):adv00195. Epub 2020 Jun 18.

Department of Dermatology, Pontevedra University Hospital, ES-36995 Pontevedra, Spain. E-mail:

Exp Ther Med 2020 Jul 20;20(1):78-86. Epub 2020 Mar 20.

Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, Faculty of Medicine, 700115 Iasi, Romania.

Early detection of skin cancer is essential in order to obtain an improved prognosis. Clinicians need more objective and non-invasive examination methods to support their decision whether to biopsy or not tumoral lesions. These may include several imaging techniques such as dermoscopy, videodermoscopy, also known as sequential digital dermoscopy (SDD), computer-aided diagnosis (CAD), total body photography, imaging and high-frequency ultrasonography (HFUS), reflectance confocal microscopy, multiphoton tomography, electrical impedance spectroscopy, Raman spectroscopy, stepwise two-photon-laser spectroscopy and quantitative dynamic infrared. Read More

Dermatol Ther (Heidelb) 2020 Jun 6. Epub 2020 Jun 6.

San Diego Family Dermatology, National City, CA, USA.

Angiokeratomas are benign vascular lesions. Genital angiokeratomas, also referred to as Fordyce angiokeratomas, usually occur on the scrotum in men and the vulva in women. Penile angiokeratoma (PEAKER) is a subtype of genital angiokeratoma in men; clitoral angiokeratoma (CLANKER) is its embryologic analog in women. Read More

Ann Dermatol Venereol 2020 Jun 3. Epub 2020 Jun 3.

Service de dermatologie, centre hospitalier Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France. Electronic address:

J Am Acad Dermatol 2020 Jun 2. Epub 2020 Jun 2.

Servicio de Dermatología. Hospital Universitario Ramón y Cajal. Departamento de Medicina, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain; Grupo de Dermatología Pedro Jaén, Madrid, Spain. Electronic address:

J Cutan Med Surg 2020 Jun 5:1203475420929922. Epub 2020 Jun 5.

929922 Hospital de Clínicas de Porto Alegre, Brazil.

Int J Dermatol 2020 Jun 4. Epub 2020 Jun 4.

EsteDerm Private Dermatology Unit, Tychy, Poland.

Background: Dermatofibroma (DF) is a common benign skin lesion in a majority of cases located on the legs or upper limbs. The etiology of DF is still unclear.

Objectives: Reflectance confocal microscopy features of DF were described. Read More

Med Image Anal 2020 May 23;64:101716. Epub 2020 May 23.

Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 518000, Shenzhen, China. Electronic address:

Skin lesion segmentation from dermoscopy images is a fundamental yet challenging task in the computer-aided skin diagnosis system due to the large variations in terms of their views and scales of lesion areas. We propose a novel and effective generative adversarial network (GAN) to meet these challenges. Specifically, this network architecture integrates two modules: a skip connection and dense convolution U-Net (UNet-SCDC) based segmentation module and a dual discrimination (DD) module. Read More

J Am Acad Dermatol 2020 May 31. Epub 2020 May 31.

Department of Dermatology & Dermoscopy, Skinnocence: the Skin Clinic & Research Centre, Gurugram, India. Electronic address:

An Acad Bras Cienc 2020 29;92(1):e20190554. Epub 2020 May 29.

Department of Electronics and Communication Engineering, Muthayammal Engineering College, Tamilnadu, India.

Skin is the outermost and largest organ of the human body that protects us from the external agents. Among the various types of diseases affecting the skin, melanoma (skin cancer) is the most dangerous and deadliest disease. Though it is one of the dangerous forms of cancer, it has a high survival rate if and only if it is diagnosed at the earliest. Read More

Postepy Dermatol Alergol 2020 Apr 6;37(2):274-276. Epub 2020 May 6.

Department of Paediatric Surgery and Urology, Wroclaw Medical University, Wroclaw, Poland.

Postepy Dermatol Alergol 2020 Apr 10;37(2):195-201. Epub 2019 Sep 10.

Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Gdańsk, Poland.

Introduction: Longitudinal melanonychia (LM) is characterized by a tan, brown or black longitudinal streak within nail plate caused by the presence of melanin. LM is relatively common in dark-skinned population, infrequent in Caucasian population, and rare in children.

Aim: We report epidemiological, clinicopathological and dermoscopic analysis of 8 cases of childhood LM from Poland, which is the largest series in the Central and Eastern European population. Read More

Postepy Dermatol Alergol 2020 Apr 5;37(2):180-183. Epub 2020 May 5.

Department of Dermatology and Venereology, Batman Medical Park Hospital, Batman, Turkey.

Introduction: There are very few studies about dermoscopic findings of fungal melanonychia (FM) apart from the case reports.

Aim: To reveal and identify dermoscopic findings which facilitate diagnosis of the FM.

Material And Methods: The study included a total of 42 nails from 33 patients diagnosed with FM on the basis of the clinical history, physical examination, dermoscopic findings and microbiological investigation. Read More

Curr Med Imaging 2020 ;16(5):513-533

Department of Computer Engineering, Bahria University, Islamabad, Pakistan.

Background: Automated intelligent systems for unbiased diagnosis are primary requirement for the pigment lesion analysis. It has gained the attention of researchers in the last few decades. These systems involve multiple phases such as pre-processing, feature extraction, segmentation, classification and post processing. Read More

An Bras Dermatol 2020 May 11. Epub 2020 May 11.

Department of Dermatology and Radiotherapy, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, São Paulo, SP, Brazil.

Syphilis is an infectious disease that has afflicted mankind for centuries, but a recent increase in worldwide incidence has been evidenced. The authors describe a patient with typical lesions of secondary syphilis and moth-eaten alopecia, whose dermoscopic examination demonstrated empty hair follicles, vellus hair, follicular hyperkeratosis, peripheral black dots, dilated and tortuous vessels, reddish brown background, and hypopigmentation of the hair shafts. Furthermore, this case presented an erythematous background more evident than previously described cases. Read More

IEEE Trans Neural Netw Learn Syst 2020 Jun 1;PP. Epub 2020 Jun 1.

A common shortfall of supervised deep learning for medical imaging is the lack of labeled data, which is often expensive and time consuming to collect. This article presents a new semisupervised method for medical image segmentation, where the network is optimized by a weighted combination of a common supervised loss only for the labeled inputs and a regularization loss for both the labeled and unlabeled data. To utilize the unlabeled data, our method encourages consistent predictions of the network-in-training for the same input under different perturbations. Read More

Dermatol Ther 2020 Jun 1:e13744. Epub 2020 Jun 1.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Italy.

Recently 5-fluorouracil 0.5% / salicylic acid 10% (5-FU/SA) topical solution has been included in the National Italian portfolio for lesion-directed treatment of grade I/II actinic keratosis (AKs) located on the face or scalp. To describe the utility of dermoscopy and RCM in treatment response monitoring of a series of AKs treated with 5-FU/SA as lesion-directed therapy. Read More

Indian Dermatol Online J 2020 Mar-Apr;11(2):298-300. Epub 2020 Mar 9.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Indian Dermatol Online J 2020 Mar-Apr;11(2):288-290. Epub 2020 Mar 9.

Department of Dermatology, Venereology, and Leprosy, Dr. KN Barua Institute of Dermatological Sciences, Guwahati, Assam, India.

A 60-year-old male patient presented with a solitary pink plaque over the inner aspect of the left forearm of 4 years duration. The lesion was persistent and unresponsive to treatment. A skin biopsy was done with differential diagnosis of lupus vulgaris, tuberculoid leprosy, and granuloma annulare. Read More

Indian Dermatol Online J 2020 Mar-Apr;11(2):282-283. Epub 2020 Mar 9.

Department of Dermatology, Medical Trust Hospital, Cochin, Kerala, India.

Indian Dermatol Online J 2020 Mar-Apr;11(2):202-207. Epub 2020 Mar 9.

Department of Pathology, S. Nijalingappa Medical College, Bagalkot, Karnataka, India.

Introduction: Dermatophytosis has become resistant and relapsing infection in India. Diagnosis of dermatophytosis is easy, however, poses diagnostic challenge in partial treatment, steroid abuse. Dermoscopy is noninvasive tool for diagnosis of many infestations and infections. Read More

Indian Dermatol Online J 2020 Mar-Apr;11(2):171-176. Epub 2020 Mar 9.

Department of Pathology, ESI-PGIMSR Hospital, Basaidarapur, Delhi, India.

Background And Aims: Melanonychia can be a manifestation of benign or malignant pathology and often poses a diagnostic challenge on clinical examination. Even with distinguishing dermoscopic features (nail plate), it can be quite difficult to determine the nature of pigmentation as complete assessment of nail bed and matrix is still not possible. Intraoperative dermoscopy (IOD) can serve as a useful tool to appreciate the bed and matrix changes. Read More