103 results match your criteria Dermoid Limbal


Progressive large pediatric corneal limbal dermoid management with tissue glue-assisted monolayer amniotic membrane transplantation: A case report.

Medicine (Baltimore) 2018 Nov;97(46):e13084

Department of Ophthalmology.

Rationale: Limbal dermoids are choristomas known as congenital benign tumors found in abnormal locations. Despite the benign nature, enlarging limbal dermoids may cause visual abnormalities by cornea infiltration with fat component, visual axis invasion, gradually induced corneal astigmatism, and finally result in anisometropic amblyopia. Here we report a rare case of progressive, large pediatric corneal limbal dermoid in a newborn, managed with tissue glue-assisted monolayer amniotic membrane transplantation. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811160-0002
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http://dx.doi.org/10.1097/MD.0000000000013084DOI Listing
November 2018
14 Reads

Prognosis after lamellar keratoplasty for limbal dermoids using preserved corneas.

Jpn J Ophthalmol 2018 Nov 12. Epub 2018 Nov 12.

Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Purpose: To evaluate the safety and efficacy of lamellar keratoplasty using preserved donor corneas to treat limbal dermoids.

Study Design: Retrospective study.

Methods: The clinical records of 19 patients with limbal dermoids, who underwent lamellar keratoplasty using preserved corneas that were observed for more than 6 months at the Keio University School of Medicine between January, 2000 and December, 2017, were retrospectively reviewed. Read More

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http://link.springer.com/10.1007/s10384-018-0639-9
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http://dx.doi.org/10.1007/s10384-018-0639-9DOI Listing
November 2018
10 Reads

Lamellar keratoplasty using femtosecond laser intrastromal lenticule for limbal dermoid: case report and literature review.

J Int Med Res 2018 Nov 8;46(11):4753-4759. Epub 2018 Aug 8.

1 Department of Ophthalmology, the First Hospital of Jilin University, Changchun, China.

Small incision refractive lenticule extraction (SMILE) is a femtosecond laser technique to correct myopia and myopic astigmatism. Herein, we report a technique where intrastromal lenticule obtained from the SMILE procedure served as a graft for lamellar keratoplasty in the management of a limbal dermoid. An 18-year-old woman presented to the clinic with a corneal-limbal mass in the right eye. Read More

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http://dx.doi.org/10.1177/0300060518790874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259413PMC
November 2018
15 Reads
1.095 Impact Factor

SCALP syndrome: What is it and its ophthalmic manifestations.

Am J Ophthalmol Case Rep 2018 Sep 21;11:10-12. Epub 2018 Apr 21.

Department of Ophthalmology, Perth Children's Hospital, QE II Medical Centre, Nedlands, Western Australia, 6009, Australia.

Purpose: To present the ophthalmic manifestations of a 3-month old female with SCALP syndrome.

Observations: The patient presented with multiple ocular anomalies including bilateral limbal dermoids, esotropia and left optic nerve hypoplasia.

Conclusions: We describe systemic and ocular anomalies in a rare case of SCALP syndrome. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058059PMC
September 2018
3 Reads

Double limbal dermoid with Tessier's paramedian facial cleft.

J AAPOS 2018 Oct 26;22(5):395-397. Epub 2018 Jul 26.

Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

We report the case of mandibulofacial dysostosis in a 9-year-old Indian boy presenting with unilateral double limbal dermoid in superotemporal and superonasal quadrants, high arched palate, and paramedian cleft in the right side of the nose with abnormal dentition. A multidisciplinary approach to treatment was advised. The dermoid cysts were excised surgically with a reconstruction of the ocular surface using multilayered amniotic membrane transplantation. Read More

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http://dx.doi.org/10.1016/j.jaapos.2018.02.006DOI Listing
October 2018
4 Reads

Conjunctival Lesions: When Should We Perform Biopsy?

Nepal J Ophthalmol 2017 Jul;9(18):160-169

Introduction: The conjunctiva is a thin and flexible mucus membrane that provides a protective barrier for the eye. Very few histopathologic studies have been conducted on biopsies from conjunctival lesions (CL) in central India.

Objective: To study the spectrum of CL and define those lesions that need attention with regard to need of biopsy in order to prevent grave sequelae and ocular morbidity. Read More

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http://dx.doi.org/10.3126/nepjoph.v9i2.19262DOI Listing
July 2017
4 Reads

Lamellar keratoplasty with corneoscleral graft for limbal dermoids.

Int J Ophthalmol 2018 18;11(3):512-515. Epub 2018 Mar 18.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida 33418, USA.

To assess the postoperative outcomes of limbal dermoid excision with corneoscleral graft transplantation. The charts of 8 consecutive patients (mean age: 13.0y) who had undergone limbal dermoid excision with lamellar corneoscleral graft transplantation by a single surgeon were retrospectively reviewed. Read More

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http://dx.doi.org/10.18240/ijo.2018.03.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861244PMC
March 2018
4 Reads

Combined interface tattooing and fibrin glue-assisted sutureless corneal resurfacing with donor lenticule obtained from small-incision lenticule extraction for limbal dermoid.

J Cataract Refract Surg 2017 Nov;43(11):1371-1375

From Dr. Agarwal's Eye Hospital and Eye Research Centre (Jacob, Narasimhan, Amar Agarwal, Athiya Agarwal, A.I.) and Dr. Agarwal's Refractive and Cornea Foundation (Jacob, A.I.), Chennai, India.

We describe a technique of small-incision lenticule extraction (SMILE)-assisted sutureless corneal resurfacing with interface tattooing for superficial limbal dermoids. After excision at a plane minimally below surrounding normal cornea and sclera, a corneal tattoo powder is carefully applied within an inked circular outline of the intended corneal margin. Circularity and cosmesis are assessed in natural light with the microscope light off. Read More

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http://dx.doi.org/10.1016/j.jcrs.2017.09.021DOI Listing
November 2017
15 Reads

New Grading System for Limbal Dermoid: A Retrospective Analysis of 261 Cases Over a 10-Year Period.

Cornea 2018 Jan;37(1):66-71

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.

Purpose: To establish a new scoring system for limbal dermoid, in order to unify the diagnostic criteria and assess the prognosis.

Methods: A retrospective study was conducted on 261 patients with limbal dermoid. The basic information, clinical features, and pathology of dermoids were recorded, and the prognosis at 1 year after keratoplasty was assessed at follow-up. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728589PMC
January 2018
15 Reads

Limbal Dermoid in a Teenage Boy.

JAMA Ophthalmol 2017 Oct 12;135(10):e173268. Epub 2017 Oct 12.

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.3268DOI Listing
October 2017
4 Reads

[A hair growing on the eye: Limbal dermoid].

J Fr Ophtalmol 2017 Nov 9;40(9):819-820. Epub 2017 Oct 9.

Service d'ophtalmologie, université de Monastir, CHU Taher Sfar, 5100 Mahdia, Tunisie.

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http://dx.doi.org/10.1016/j.jfo.2017.02.011DOI Listing
November 2017
4 Reads

Optical Coherence Tomography-Assisted Limbal Dermoid Removal.

J Pediatr Ophthalmol Strabismus 2017 Oct 9;54:e58-e59. Epub 2017 Oct 9.

This report and accompanying video show the novel use of intraoperative optical coherence tomography (OCT) in the excision of a limbal dermoid. Examining for residual opaque tissue in the cornea accompanied by OCT imaging is a useful technique to confirm complete excision of the lesion. [J Pediatr Ophthalmol Strabismus. Read More

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http://www.healio.com/doiresolver?doi=10.3928/01913913-20170
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http://dx.doi.org/10.3928/01913913-20170810-03DOI Listing
October 2017
28 Reads

Encephalocraniocutaneous lipomatosis: A case report with review of literature.

Neuroradiol J 2017 Dec 14;30(6):578-582. Epub 2017 Jul 14.

1 Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, India.

Encephalocraniocutaneous lipomatosis (ECCL) or Haberland syndrome is an uncommon sporadic neurocutaneous syndrome of unknown origin. The rarity and common ignorance of the condition often makes diagnosis difficult. The hallmark of this syndrome is the triad of skin, ocular and central nervous system (CNS) involvement and includes a long list of combination of conditions. Read More

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http://dx.doi.org/10.1177/1971400917693638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703133PMC
December 2017
11 Reads

Partial Encephalocraniocutaneous Lipomatosis Syndrome.

J Pediatr Neurosci 2017 Jan-Mar;12(1):102-104

Department of Paediatric Neurology, Stanley Medical College, Chennai, Tamil Nadu, India.

Encephalocranial lipomatosis is a rare disorder that characteristically involves ectomesodermal tissues such as skin, eye, and the central nervous system. Here, we report a 3-year-old girl presented with developmental delay, seizures, limbal dermoid, and weakness of right lower limb. Imaging revealed hemiatrophy, arachnoid cyst, and polymicrogyria. Read More

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http://dx.doi.org/10.4103/jpn.JPN_130_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437771PMC
May 2017
8 Reads

[Allogeneic cultured limbal epithelial transplantation: a clinical observation of its treatment effects on large conjunctival lesions].

Zhonghua Yan Ke Za Zhi 2017 Mar;53(3):172-176

Qingdao Eye Hospital, Shandong Eye Institute, Qingdao 266071, China.

To introduce the surgical methods and investigate the treatment effects of conjunctival lesion resection combined with transplantation of allogeneic limbal epithelia cultured in vitro for treatment of varied large conjunctival lesions. A retrospective analysis of case data of the patients receiving transplantation of allogeneic limbal epithelia cultured in vitro for large conjunctival lesions at Qingdao Eye Hospital from January 2013 to December 2015 was conducted. Fresh donor corneal limbal epithelial tissues were obtained for cellular digestion and isolation. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2017.03.005DOI Listing
March 2017
3 Reads

Surgical management of limbal dermoids: 10-year review.

Acta Ophthalmol 2017 09 7;95(6):e517-e518. Epub 2017 Mar 7.

Joint Shantou International Eye Center of ShanTou University, The Chinese University of Hong Kong, ShanTou, China.

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http://dx.doi.org/10.1111/aos.13423DOI Listing
September 2017
4 Reads

Ocular dermoid in Pai Syndrome: A review.

Eur J Med Genet 2017 Apr 23;60(4):217-219. Epub 2017 Jan 23.

National Maternity Hospital, Holles St., Dublin, D02 YH21, Ireland; Children's University Hospital, Temple Street, Dublin, D01 YC67, Ireland. Electronic address:

Pai Syndrome is a rare congenital malformation syndrome of unknown cause with hypertelorism, midline cleft lip, nasal and facial polyps, ocular anomalies and the presence of distinctive lipomas adjacent to the corpus callosum. Herein, we present an infant girl with Pai Syndrome diagnosed in the first week of life with typical facial findings and associated pericallosal lipoma identified on cranial ultrasound and brain MRI. These typical features identified included median cleft of the upper lip (in her case as a forme fruste) with a cleft alveolus and a mid-anterior alveolar process congenital polyp. Read More

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http://dx.doi.org/10.1016/j.ejmg.2017.01.008DOI Listing
April 2017
7 Reads

Preoperative evaluation and outcome of corneal transplantation for limbal dermoids: a ten-year follow-up study.

Int J Ophthalmol 2016 18;9(12):1756-1760. Epub 2016 Dec 18.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan 250021, Shandong Province, China.

Aim: To summarize preoperative evaluation and outcome of corneal transplantation for limbal dermoids for ten years.

Methods: Eighty-five patients diagnosed with limbal dermoids and treated with corneal transplantation were analyzed retrospectively. All patients were further divided into two groups according to absence or presence of neovascularization surrounding the dermoids in the corneal stroma. Read More

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http://dx.doi.org/10.18240/ijo.2016.12.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154988PMC
December 2016
6 Reads

Late Recognition of a Case of Oculo-Auriculo-Vertebral Spectrum.

Optom Vis Sci 2016 11;93(11):1449-1453

*MD, PhD †MD, FRCS, FRCOphth Department of Ophthalmology, King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia (JEM); Department of Surgery, North Bronx Health Network, Bronx, New York (JNM); and Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York (JNM).

Purpose: To report the late recognition of a case oculo-auriculo-vertebral spectrum (OAVS).

Case Report: A 14-year-old male patient with a history of spinal scoliosis and anal atresia presented with a right ocular growth that was increasing in size and causing irritation. He was discovered to have a right limbal dermoid and forniceal lipodermoid. Read More

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http://dx.doi.org/10.1097/OPX.0000000000001002DOI Listing
November 2016
3 Reads

Surgical Management of Limbal Dermoids Using Anterior Corneal Buttons From Descemet Stripping Automated Endothelial Keratoplasty Donor Tissue as Patch Grafts.

Cornea 2017 Jan;36(1):64-67

*Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan; †Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan; ‡Sydney Medical School, University of Sydney, Sydney, Australia; and §Center of Corneal Tissue Engineering and Stem Cell Biology, National Taiwan University Hospital, Taipei, Taiwan.

Purpose: To assess the surgical and clinical outcomes of anterior lamellar keratoplasty using anterior corneal buttons from Descemet stripping automated endothelial keratoplasty (DSAEK) donor tissue.

Methods: Retrospective data from 8 patients with unilateral limbal dermoids, treated between February 2011 and January 2016 at National Taiwan University Hospital, were analyzed. Donor corneas for DSAEK were divided into anterior and posterior lamellae using a 350-μm microkeratome. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001021DOI Listing
January 2017
11 Reads

Phenotypic characterization of epibulbar dermoids.

Int Ophthalmol 2017 Jun 12;37(3):499-505. Epub 2016 Jul 12.

Seattle Children's Research Institute, Seattle, WA, USA.

The purpose of this study was to characterize the phenotypic presentation, clinical course, and outcomes of epibulbar dermoids (EpDs) which are the most common congenital eye tumor in children. Sixty-eight dermoids were identified in 58 eyes of 48 patients of Seattle Children's Hospital between 1981 and 2014 via electronic medical record search. Patients were organized into: "EpD-Only" [patients without other congenital anomalies (n = 13)], "EpD-CFM" [patients with a craniofacial microsomia (CFM) diagnosis (n = 25)], and "EpD-Other" [patients with other congenital anomalies (n = 10)]. Read More

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http://dx.doi.org/10.1007/s10792-016-0285-5DOI Listing
June 2017
5 Reads

Sutureless Lamellar Corneoscleral Patch Graft With Fibrin Sealant for Limbal Dermoid Removal.

J Pediatr Ophthalmol Strabismus 2016 Jun 3;53 Online:e22-5. Epub 2016 Jun 3.

A 2-year-old boy with Goldenhar syndrome had a limbal dermoid removed and covered with a lamellar corneoscleral patch graft that was attached with fibrin glue and no sutures. The graft healed and attached well. A sutureless technique is beneficial due to decreased scarring and chance of infection. Read More

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http://dx.doi.org/10.3928/01913913-20160509-03DOI Listing
June 2016
3 Reads

Shave Excision With Keratopigmentation for Limbal Dermoid.

Eye Contact Lens 2018 Mar;44(2):e7-e9

Division of Cornea and Refractive Surgery (P.B.), Department of Ophthalmology, Doctor Eye Institute, Mumbai, Maharashtra, India; and Division of Cornea and Refractive Surgery (T.S., T.A.), Department of Ophthalmology, Rajendra Prasad Institute of Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Objectives: To describe a modified technique of corneal tattooing for concomitant cosmetic rehabilitation in eyes with limbal dermoid.

Study: Case series.

Methods: Three patients between 12 and 20 years of age with grade I limbal dermoid underwent shave excision with corneal tattooing. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000257DOI Listing
March 2018
6 Reads
1.680 Impact Factor

A microanatomic abnormality of the lacrimal gland associated with Goldenhar syndrome.

Surv Ophthalmol 2016 Sep-Oct;61(5):654-63. Epub 2016 Feb 16.

Department of Pathology, Wills Eye Institute, Jefferson Medical College, Philadelphia, Pennsylvania, USA.

A 12-month-old male infant, noted from birth to have a diffuse right temporal epibulbar thickening that encroached on the limbus inferotemporally, was found to manifest stigmata of Goldenhar syndrome, including a limbal dermoid with vellus hairs, esotropia, astigmatism, fullness and ectropion of the lower eyelid, preauricular skin tag, agenesis of the right kidney, and a supernumerary rib. In the excised epibulbar specimen, in addition to a solid dermoid, lobules of lacrimal gland tissue were interpreted as a portion of the palpebral or orbital lobes. This tissue displayed a unique histopathologic finding. Read More

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http://dx.doi.org/10.1016/j.survophthal.2016.02.002DOI Listing
May 2017
3 Reads

Demodex spp. within the limbal dermoid – causal pathogen or an irrelevant finding? Case report.

Klin Oczna 2016;118(2):136-8

The aim of the study is to report a case of limbal dermoid associated with infestation of Demodex species (Demodex spp.). A 27-year-old man presented with ocular discomfort and a pink conjunctival lesion in his left eye. Read More

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Clinical decision upon resection or observation of ocular surface dermoid lesions with the visual axis unaffected in pediatric patients.

Authors:
Toshihiko Matsuo

Springerplus 2015 21;4:534. Epub 2015 Sep 21.

Department of Ophthalmology, Okayama University Medical School and Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama City, 700-8558 Japan.

Ocular surface or epibulbar dermoid lesions may present as limbal dermoids at the corneal limbus or dermolipomas in the conjunctival fornix. The purpose of this study is to review clinical features of ocular surface dermoids (grade I), with the visual axis unaffected, in pediatric patients, in order to find key features for making clinical decision, either resection or observation. The study involved 13 consecutive patients with limbal dermoids or fornix dermolipomas which did not affect the visual axis, seen in 11 years at a referral-based institution. Read More

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http://dx.doi.org/10.1186/s40064-015-1326-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577497PMC
September 2015
2 Reads

Transcription Factor PAX6 (Paired Box 6) Controls Limbal Stem Cell Lineage in Development and Disease.

J Biol Chem 2015 Aug 4;290(33):20448-54. Epub 2015 Jun 4.

the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China, the Department of Ophthalmology, Biomaterials and Tissue Engineering Center, Institute for Engineering in Medicine.

PAX6 is a master regulatory gene involved in neuronal cell fate specification. It also plays a critical role in early eye field and subsequent limbal stem cell (LSC) determination during eye development. Defects in Pax6 cause aniridia and LSC deficiency in humans and the Sey (Small eye) phenotype in mice (Massé, K. Read More

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http://www.jbc.org/content/290/33/20448.full.pdf
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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.662940
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http://dx.doi.org/10.1074/jbc.M115.662940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536450PMC
August 2015
17 Reads

Congenital complex corneal choristoma associated with unilateral bony calvarial defects, subcutaneous nodules, and alopecia.

J AAPOS 2015 Apr;19(2):185-8

Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah. Electronic address:

Complex corneal choristoma is a rare finding and its relationship with systemic disease is poorly understood. We present a 3-day-old boy with the constellation of left-sided congenital complex corneal choristoma, limbal dermoid, ipsilateral bony skull defects, and bilateral subcutaneous vascularized nodules with overlying alopecia and scalp nevi. To our knowledge this is the first case of complex choristoma involving the presence of associated bony calvarial defects. Read More

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http://dx.doi.org/10.1016/j.jaapos.2014.10.034DOI Listing
April 2015
2 Reads

New surgical approach for limbal dermoids in children: simple excision, corneal tattooing, and sutureless limboconjunctival autograft.

Cornea 2015 Jun;34(6):720-3

*Department of Ophthalmology, Jeju National University College of Medicine, Jeju, Korea; and †Department of Ophthalmology, Seonam University College of Medicine, Myongji Hospital, Goyang, Korea.

Purpose: To evaluate the efficacy of combined surgery of simple excision, corneal tattooing, and a sutureless limboconjunctival autograft in pediatric patients with grade 1 limbal dermoids.

Methods: We treated 4 eyes of 4 patients with combined surgery of corneal tattooing and a sutureless limboconjunctival autograft with simple excision of limbal dermoids. Preoperative and postoperative visual acuity, postoperative recovery time, cosmetic improvements, patient compliance, and complication rates were reviewed. Read More

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http://pdfs.journals.lww.com/corneajrnl/2015/06000/New_Surgi
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ICO.0000000000000440DOI Listing
June 2015
32 Reads

Corneal Fine Needle Diathermy With Adjuvant Bevacizumab to Treat Corneal Neovascularization in Children.

Cornea 2015 Jul;34(7):773-7

Department of Ophthalmology and Vision Sciences, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

Purpose: To report the outcomes of corneal fine needle diathermy (FND) with adjuvant intrastromal and subconjunctival bevacizumab injection for corneal neovascularization (CN) in children.

Methods: Medical records of all children who had undergone FND with adjuvant bevacizumab injection were reviewed retrospectively. Treatment efficacy was evaluated by changes in visual acuity, regression of CN, and clearing of lipid deposits with the aid of slit-lamp color images that were taken before surgical intervention and at last follow-up visit. Read More

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http://pdfs.journals.lww.com/corneajrnl/2015/07000/Corneal_F
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ICO.0000000000000419DOI Listing
July 2015
3 Reads

Encephalocraniocutaneous lipomatosis: a case report and review of the literature.

Indian J Ophthalmol 2014 May;62(5):622-7

Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.

Encephalocraniocutaneous lipomatosis (ECCL) is a rare, sporadic congenital neurocutaneous disorder that characteristically involves ectomesodermal tissues, such as skin, eyes, and central nervous system. A 3-day-old girl presented with swelling in her right eye since birth. Ocular examination of the right eye showed hypertrophy of bulbar conjunctiva with limbal dermoid, clouding of cornea, and atypical upper eyelid coloboma. Read More

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http://dx.doi.org/10.4103/0301-4738.133521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065518PMC
May 2014
3 Reads

The outcomes of primary pediatric keratoplasty in Singapore.

Am J Ophthalmol 2014 Sep 27;158(3):496-502. Epub 2014 May 27.

Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Duke-National University of Singapore Graduate Medical School Singapore, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

Purpose: To evaluate the long-term corneal graft survival and risk factors for graft failure in pediatric eyes.

Design: Retrospective, interventional consecutive case series.

Methods: Unilateral eyes of 105 patients aged 16 years and below were included from the Singapore Corneal Transplant Study between April 4, 1991 and April 4, 2011. Read More

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http://dx.doi.org/10.1016/j.ajo.2014.05.020DOI Listing
September 2014
10 Reads
3.870 Impact Factor

Surgical management of corneal limbal dermoids: retrospective study of different techniques and use of Mitomycin C.

Eye (Lond) 2014 Jul 23;28(7):857-62. Epub 2014 May 23.

Department of Ophthalmology, University Eye Hospital Freiburg, Freiburg im Breisgau, Germany.

Purpose: We retrospectively studied the efficacy and safety of different surgical approaches to treating pediatric limbal dermoids with regard to intra and postoperative complications.

Methods: The data of 12 consecutive patients (14 eyes), who underwent monocentric surgery of a limbal demoid in the past 9 years, were retrospectively analyzed for intra and postoperative complications. Group one consists of eleven eyes: seven eyes with a bare-sclera deep lamellar excision of the dermoid and four eyes with an additional amniotic membrane transplantation subsequent to excision. Read More

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http://dx.doi.org/10.1038/eye.2014.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094805PMC
July 2014
2 Reads

Unilateral Morning Glory Disc Anomaly With Ipsilateral Limbal Dermoids.

J Pediatr Ophthalmol Strabismus 2014 May 28;51 Online:e37-9. Epub 2014 May 28.

The authors present the case of a child with multiple limbal dermoids and morning glory disc anomaly in the right eye. These anomalies are rarely associated and this is the first report of co-occurrence in the same eye in a patient without additional systemic anomalies. Read More

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http://dx.doi.org/10.3928/01913913-20140521-03DOI Listing
May 2014
3 Reads

In vivo confocal microscopy in goldenhar syndrome: a case report.

BMC Ophthalmol 2013 Oct 16;13:55. Epub 2013 Oct 16.

Cornea and Ocular Surface Unit, San Raffaele Scientific Institute, Milan, Italy.

Background: Goldenhar Syndrome is characterized by malformations of multiple anatomical districts. Between these, bulbar dermoids are common and represent a significant clinical problem as they can affect both ocular function and aesthetic comfort.Histologic characterization of dermoids has been extensively performed; however, no reports exist describing in vivo confocal microscopy (IVCM) of these lesions. Read More

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http://dx.doi.org/10.1186/1471-2415-13-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853195PMC
October 2013
7 Reads

Simple keratectomy and corneal tattooing for limbal dermoids: results of a 3-year study.

Int J Ophthalmol 2013 18;6(4):463-6. Epub 2013 Aug 18.

Department of Ophthalmology, Jeju National University College of Medicine, Jeju National University Hospital, Jeju, Korea.

Aim: To evaluate and report the efficacy of combined surgical excision and corneal tattooing in patients with limbal dermoids.

Methods: In a retrospective interventional case series, 9 eyes of 8 patients were treated with combined surgery of simple keratectomy and corneal tattooing for limbal dermoids. Medical records, including best-corrected visual acuity, anterior segment photography, demographic, clinical data, and follow-up information were reviewed. Read More

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http://dx.doi.org/10.3980/j.issn.2222-3959.2013.04.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755304PMC
August 2013
5 Reads

Encephalocraniocutaneous Lipomatosis (Haberl and syndrome): A case report and review of literature.

Indian J Dermatol 2013 May;58(3):232-4

Department of Pathology, NRI Medical College and General Hospital, Guntur District, Andhra Pradesh, India.

Encephalocraniocutaneous lipomatosis (ECCL) is a rare sporadic neurocutaneous syndrome characterized by presence of central nervous system, ocular and cutaneous anomalies. The exact pathogenesis is still not known. We present the third case from the Indian subcontinent, who is a five year old girl with history of right sided seizures. Read More

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http://dx.doi.org/10.4103/0019-5154.110835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667289PMC
May 2013
2 Reads
5 Citations

Limbal dermoid in Nager acrofacial dysostosis: a rare case report.

Indian J Ophthalmol 2014 Mar;62(3):339-41

Department of Oral Medicine and Radiology, Subharti Dental College and Hospital, Meerut, Uttar Pradesh, India.

Nager syndrome, also called preaxial acrofacial dysostosis, comprises two groups of defects involving the limbs and craniofacial region, respectively. This syndrome is rare and only 70 cases have been reported in the literature. The exact cause of this syndrome is unknown, but there is indication that it is genetically based. Read More

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http://dx.doi.org/10.4103/0301-4738.111194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061675PMC
March 2014
9 Reads
0.930 Impact Factor

Management of pediatric corneal limbal dermoids.

Authors:
Amir Pirouzian

Clin Ophthalmol 2013 28;7:607-14. Epub 2013 Mar 28.

Tayani Institute, Division of Ophthalmology and Cornea, Mission Viejo in affiliation with Children's Hospital of Orange County at Mission Hospital, CA, USA ; Rady's Children's Hospital of San Diego, San Diego, CA, USA.

This paper reviews the data in the published literature (PubMed from 1937 to 2011) concerning the medical and surgical management of pediatric limbal dermoids. Current standard medical treatment for grade I pediatric limbal dermoids (ie, with superficial corneal involvment) is initially conservative. In stages II (ie, affecting the full thickness of the cornea with/without endothelial involvement) and III (ie, involvement of entire cornea and anterior chamber), a combination of excision, lamellar keratoplasty, and amniotic membrane and limbal stem cell tranplantation are advocated. Read More

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http://dx.doi.org/10.2147/OPTH.S38663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616691PMC
April 2013
3 Reads
6 Citations

Limbal dermoid epithelium shares phenotypic characteristics common to both hair epidermal and limbal epithelial stem cells.

Curr Eye Res 2013 Aug 10;38(8):835-42. Epub 2013 Apr 10.

Save Sight Institute, University of Sydney, NSW, Australia.

Purpose: To determine putative limbal epithelial stem cell marker expression in human limbal dermoids compared to stem cell niches in normal limbus and hair follicles of normal human dermis.

Methods: Human limbal dermoids (n = 7), normal skin (n = 2) and normal limbal (n = 7) tissue were examined. Immunohistochemistry was performed on paraffin embedded specimens using automated and manual immunostaining with primary antibodies to CK15, CK14, Cadherin-P (CDH3), Wnt-3, Wnt-4, Wnt-5a, Dickkopf (DKK)-3, Sox-2, Sox-10, Sox-13, PEDF, NGFR p75 and β-catenin. Read More

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http://dx.doi.org/10.3109/02713683.2013.780625DOI Listing
August 2013
9 Reads

Images in clinical medicine. The hairy eyeball--limbal dermoid.

N Engl J Med 2013 Jan;368(1):64

Tabriz University of Medical Sciences, Tabriz, Iran.

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http://dx.doi.org/10.1056/NEJMicm1208993DOI Listing
January 2013
2 Reads

[Limbal dermoid in Goldenhar syndrome].

Pan Afr Med J 2013 24;15:69. Epub 2013 Jun 24.

Université Mohammed V Souissi, service d'ophtalmologie A de l'hôpital des spécialités, Centre hospitalier universitaire, Rabat, Maroc.

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http://dx.doi.org/10.11604/pamj.2013.15.69.2844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061503PMC
February 2015
2 Reads

Deep anterior lamellar keratoplasty in children.

Am J Ophthalmol 2013 Mar 4;155(3):570-574.e1. Epub 2012 Dec 4.

L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India.

Purpose: To evaluate the outcomes of deep anterior lamellar keratoplasty (DALK) in children.

Design: Retrospective interventional case series.

Methods: setting: Institutional, L. Read More

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http://dx.doi.org/10.1016/j.ajo.2012.09.029DOI Listing
March 2013
1 Read

Studies of a pedigree with limbal dermoid cyst.

Int J Ophthalmol 2012 18;5(5):641-3. Epub 2012 Oct 18.

Ophthalmic Laboratories and Department of Ophthalmology, Translational neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Aim: To study clinical features and gene mutations within the paired-like homeodomain transcription factor 2 (PITX2) gene in a pedigree of bilateral limbal dermoids.

Methods: Complete eye examinations have been performed on each individual of the family. Exons of paired-like homeodomain transcription factor 2 (PITX2) were amplified by polymerase chain reaction, sequenced, and compared with a reference database. Read More

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http://dx.doi.org/10.3980/j.issn.2222-3959.2012.05.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484697PMC
November 2012
52 Reads

An unusual association of Goldenhar syndrome.

Int Ophthalmol 2013 Feb 29;33(1):91-4. Epub 2012 Sep 29.

Department of Ophthalmology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.

Goldenhar syndrome is well known for its classical triad of epibulbar dermoids or lipodermoids, auricular appendages and pretragal fistulas. Here we report a case of Goldenhar syndrome with an unusual association of a fibroepithelial polyp attached to a limbal dermoid. A case of Goldenhar syndrome in a 5-month-old male infant presented with the features of a fibroepithelial polyp attached to a limbal dermoid, right-sided polydactylia with hypoplastic thumb, and accessory preauricular appendages on the left side. Read More

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http://dx.doi.org/10.1007/s10792-012-9631-4DOI Listing
February 2013
3 Reads

Thrombophilia gene mutations in oculoauriculovertebral spectrum.

Genet Couns 2012 ;23(1):65-72

Department of Medical Genetics, Gazi University, Faculty of Medicine, Ankara, Turkey.

Oculoauriculovertebral spectrum or Goldenhar syndrome is a phenotypically and probably genetically heterogeneous disorder characterized by hemifacial microsomia (unilateral ear abnormalities and ipsilateral mandibular hypoplasia) as well as vertebral anomalies and epibulbar dermoid/lipodermoids. Although most cases of the Goldenhar syndrome are sporadic, both autosomal recessive and dominant inheritance have been reported so far. In this report, we describe the clinical aspects of two familial cases with evidence of autosomal dominant inheritance and a non-familial case, and compare them with the reports in the literature. Read More

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July 2012
2 Reads

Sebaceous nevus syndrome, central nervous system malformations, aplasia cutis congenita, limbal dermoid, and pigmented nevus syndrome.

Pediatr Dermatol 2012 May-Jun;29(3):365-7. Epub 2011 Nov 28.

Department of Dermatology and Mackay Memorial Hospital, Taipei, Taiwan.

SCALP syndrome is an acronym describing the coincidence of sebaceous nevus syndrome, central nervous system malformations, aplasia cutis congenita, limbal dermoid, and pigmented nevus (giant congenital melanocytic nevus). We present a fourth case of this syndrome. Read More

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http://doi.wiley.com/10.1111/j.1525-1470.2011.01639.x
Publisher Site
http://dx.doi.org/10.1111/j.1525-1470.2011.01639.xDOI Listing
September 2012
4 Reads

Surgical management of pediatric limbal dermoids with sutureless amniotic membrane transplantation and augmentation.

J Pediatr Ophthalmol Strabismus 2012 Mar-Apr;49(2):114-9. Epub 2011 Aug 30.

Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, Med Surge I, Irvine, CA 92697, USA.

Purpose: To further evaluate the efficacy of a new surgical technique for removal of pediatric corneal-limbal dermoids and ocular surface reconstruction using multilayered amniotic membrane.

Methods: Three pediatric patients with corneal-limbal dermoid (grade I) in one practice were identified in a retrospective fashion. All patients underwent deep lamellar excision followed by sutureless multilayered amniotic membrane transplantation by a single surgeon (AP). Read More

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http://search.proquest.com/openview/3fa2908159f749dbac20018c
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http://www.slackinc.com/doi/resolver.asp?doi=10.3928/0191391
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http://dx.doi.org/10.3928/01913913-20110823-01DOI Listing
July 2013
3 Reads
7 Citations
0.731 Impact Factor

[A case of neurocutaneous melanosis associated with focal cortical dysplasia].

No To Hattatsu 2011 Jul;43(4):300-3

Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira, Tokyo.

A newborn baby boy presented with giant melanocytic nevi on the face, trunk and extremities, and focal cortical dysplasia on MRI. At 3 months of age, he developed intractable epilepsy, and MRI at 2 years of age revealed a high-intensity area in the bilateral cerebellum on T1-weighted images, indicative of melanosis. Based on the findings of the skin and MRI, we diagnosed the boy with neurocutaneous melanosis. Read More

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July 2011
1 Read

Images in clinical medicine. Limbal dermoid.

N Engl J Med 2011 Feb;364(6):e9

Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.

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http://dx.doi.org/10.1056/NEJMicm1005854DOI Listing
February 2011
2 Reads