201,842 results match your criteria Dermatology Times[Journal]


Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways.

Cell Microbiol 2018 Dec 14:e12993. Epub 2018 Dec 14.

Institute for Microbiology and Hygiene, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

The obligate intracellular bacterium Chlamydia trachomatis replicates in a cytosolic vacuole in human epithelial cells. Infection of human cells with C. trachomatis causes substantial changes to many host cell signalling pathways but the molecular basis of such influence is not well understood. Read More

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December 2018

Basic chemical peeling-superficial and medium-depth peels.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Chemical peeling, or chemexfoliation, has been used for centuries to improve signs of ultraviolet light-induced sun damage. Over the last 30 years, the science behind chemical peeling has evolved, increasing our understanding of the role of peeling ingredients and treatment indications. The depth of peels is directly related to improved results and to the number of complications that can occur. Read More

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December 2018

Access to Dermatology Services at Free Medical Clinics, A Nationwide Cross-sectional Survey.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Institute of Public and Preventative Health, Augusta University. Electronic address:

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December 2018

Advanced chemical peels: phenol-croton oil peel.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Once considered the gold standard for deep facial resurfacing, the classical Baker-Gordon phenol-croton oil peel has largely been replaced by formulas with lower concentrations of phenol and croton oil. The improved safety profile of deep peels has ushered in a new era in chemical peeling. Wrinkles can be improved and skin tightened with more subtle and natural results. Read More

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December 2018
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The role of the skin microbiome in atopic dermatitis.

Ann Allergy Asthma Immunol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, University of California, San Diego, CA,. Electronic address:

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December 2018
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Benefit of Mohs Micrographic Surgery Over Wide Local Excision for Melanoma of the Head and Neck: A Rational Approach to Treatment.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

All authors are affiliated with the Department of Dermatology, University of Minnesota Medical School, Minneapolis, Minnesota.

Background: There are limited published data comparing wide local excision (WLE) with Mohs micrographic surgery (MMS) for the treatment of melanoma.

Objective: To describe a novel treatment algorithm for the surgical management of head and neck melanoma and compare rates of local recurrence for tumors treated with either MMS using immunohistochemistry or WLE.

Materials And Methods: A 10-year retrospective chart review including all in situ and invasive melanomas of the head and neck treated at one institution from January 2004 to June 2013. Read More

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December 2018

Clinical Evaluations of a Novel Thread Lifting Regimen Using Barbed Polyglyconate Suture for Facial Rejuvenation: Analysis Using a 3-Dimensional Imaging System.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Oaro Dermatology Clinic, Seoul, Republic of Korea.

Background: Thread lifting with absorbable sutures has recently gained prominence for rejuvenating ptotic and sagging soft tissues in aging face. A barbed, delayed absorbable polyglyconate monofilament shows significantly high tensile loads with superior flexibility and elasticity.

Objective: To evaluate the safety and efficacy of novel thread lifting regimen with barbed polyglyconate suture for counteracting the descent and laxity of the aging face. Read More

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December 2018
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A Survey of Mohs Tissue Tracking Practices.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, MD Anderson Cancer Center, Houston, Texas.

Background: There are little data regarding error within the multistep process of Mohs micrographic surgery (MMS).

Objective: A survey of Mohs surgeons was performed to evaluate variation in tissue handling and processing within the MMS process.

Methods And Materials: A 9-question electronic survey was distributed to members of the American College of Mohs Micrographic Surgery. Read More

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December 2018

The "Sketch, Etch, and Sketch" Approach to Improve Accuracy and Durability of Surgical Skin Markings: Surgical Pearl.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Geisinger, Danville, Pennsylvania.

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December 2018
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Discrepancy Between Online Images of Mohs Surgery and Reality: An Opportunity for Improvement.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, University of Minnesota, Minneapolis, Minnesota Department of Dermatology, Saint Louis University, St. Louis, Missouri.

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December 2018

Experiences of Dermatologic Surgeons With the Sunshine Act: A National Survey.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania Department of Dermatology, University of California, Irvine, California Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania Department of Dermatology, University of California, Irvine, California.

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December 2018

Repair of a Large Glabellar/Nasal Defect.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Mohs Micrographic and Skin Surgery PLLC, San Antonio, Texas.

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December 2018
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Effect of Macrolide Prophylactic Therapy on AIDS-Defining Conditions and HIV-Associated Mortality.

J Acquir Immune Defic Syndr 2018 Dec 10. Epub 2018 Dec 10.

Research Institute for Tropical Medicine, Muntinlupa City, Philippines.

Background: Mycobacterium avium complex (MAC) prophylaxis is recommended for patients with advanced HIV infection. With the decrease in incidence of disseminated MAC infection and the availability of antiretroviral therapy (ART), the benefits of macrolide prophylaxis were investigated. This study examined the impact of macrolide prophylaxis on AIDS-defining conditions and HIV-associated mortality in a cohort of HIV-infected patients on ART. Read More

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December 2018

Review of light parameters and photobiomodulation efficacy: dive into complexity.

J Biomed Opt 2018 Dec;23(12):1-17

Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States.

Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is still no agreement on the parameters and protocols for its clinical application. Some groups have recommended the use of a power density less than 100  mW/cm2 and an energy density of 4 to 10  J/cm2 at the level of the target tissue. Others recommend as much as 50  J/cm2 at the tissue surface. Read More

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December 2018
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Survey on the status of teledermatology in Austria.

J Dtsch Dermatol Ges 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Graz Medical University, Graz, Austria.

Background: The use of digital communication media is becoming increasingly important, with the primary aim of improving both treatment quality and patients' quality of life. In an effort to optimize telemedicine in the field of dermatology, we conducted a survey among dermatologists in Austria.

Methods: Statistical analysis of a questionnaire that was developed by a working group and sent to 769 Austrian dermatologists. Read More

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December 2018

Mycosis fungoides, Psoriasis and Anti-PD-1 - A New Aspect of Known Associations.

J Dtsch Dermatol Ges 2018 Dec 14. Epub 2018 Dec 14.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medicine, New York, NY, USA.

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December 2018

Lethal thrombocytopenia in a patient treated with avelumab for metastatic Merkel cell carcinoma.

J Dtsch Dermatol Ges 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Venereology and Allergology, Leipzig University Medical Center, Leipzig, Germany.

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December 2018

A homozygous MITF mutation leads to familial Waardenburg syndrome type 4.

Am J Med Genet A 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology - Head and Neck Surgery, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Waardenburg syndrome (WS) is a genetic disorder characterized by hearing loss and pigmentary abnormalities with variable penetrance. Though heterozygous mutations in MITF are a major cause for Waardenburg syndrome type 2 (WS2), homozygous mutations in this gene and the associated phenotype have been rarely characterized. In this study, we identified a novel p. Read More

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December 2018
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Acitretin may improve symptoms and exudation in patients affected by elephantiasis nostras verrucosa: Report of a case.

Int Wound J 2018 Dec 13. Epub 2018 Dec 13.

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

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December 2018

Dermapen in the treatment of wrinkles in cigarette smokers and skin aging effectively.

J Cosmet Dermatol 2018 Dec;17(6):1200-1204

Department of Dermatology & Venereology, Medical School, Zagazig University, Cairo, Egypt.

Skin aging is a complex biological process that arises from two basic processes: intrinsic aging (influenced by genetics factors, cellular metabolism, hormone, and metabolic processes) and extrinsic aging caused by chronic light exposure, pollution, ionizing radiation, chemicals, toxins (Expert Opin Biol Ther. 2008;8:393). Intrinsic aging called also chronological aging is observed in sun-protected skin of elderly persons. Read More

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December 2018
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Whole exome sequencing identified two point mutations of COL7A1 and FLG in a Chinese family with dystrophic epidermolysis bullous pruriginosa and ichthyosis vulgaris.

J Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, China.

We report a 21-year-old man with recurrent bullous eruptions and severe itching on the lower legs and feet since 5 years of age. Dry, dirty brown, tile-like scales covered his lower legs with dystrophic toenails. Nodular prurigo-like lesions, scarring papules and milia remitted after the bullous eruptions. Read More

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December 2018

Evaluation of the efficacy of granulocyte and monocyte adsorption apheresis on skin manifestation and joint symptoms of patients with pustulotic arthro-osteitis.

J Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Tokyo Medical University, Tokyo, Japan.

Pustulotic arthro-osteitis, occasionally complicated with palmoplantar pustulosis, affects patients' activities of daily living. Granulocyte and monocyte adsorption apheresis selectively removes activated granulocytes and monocytes by means of extracorporeal circulation. Although the efficacy of granulocyte and monocyte adsorption apheresis in the treatment of generalized pustular psoriasis has been proved, very few reports have assessed its efficacy in the treatment of palmoplantar pustulosis and pustulotic arthro-osteitis. Read More

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December 2018
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Case of tinea nigra on the sole: Correspondences between dermoscopic and histological findings.

J Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

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December 2018

Longitudinal leukoxanthonychia of the thumb.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Hospital Universitario Donostia, Donostia, Spain.

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December 2018

Polymorphic eruption of pregnancy in Mexico.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Facultad de Medicina, Human Anatomy Department, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.

Background: Currently, the exact incidence of Polymorphic Eruption of Pregnancy (PEP) in the Mexican population is unknown. PEP tends to manifest in the abdomen, primarily in the stretch marks caused by distension. It is characterized by severely pruritic urticarial-like papules that converge in plaques, extending to the buttocks and proximal thighs. Read More

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December 2018
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The effect of anti-IL-17 treatment on the reaction to a nickel patch test in patients with allergic contact dermatitis.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.

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December 2018

Aggressive subcutaneous trichoblastomas successfully treated with Mohs micrographic surgery.

Australas J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Advocate Illinois Masonic Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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December 2018

Histopathologic correlation of high-risk MelaFind lesions: a 3-year experience from a high-risk pigmented lesion clinic.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Dermatology and Plastic Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: A significant number of pigmented lesions are biopsied to rule out melanoma, but most will be benign. MelaFind is a highly sensitive, noninvasive computer-assisted system to aid in clinical diagnosis of melanoma.

Methods: A total of 140 high-risk patients were followed by one expert dermatologist. Read More

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December 2018

Is blister grafting an acceptable answer to treating nevus depigmentosus?

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Faculty of Dermatology, College of Medicine, King Faisal University, Al Ahsa, Saudi Arabia.

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December 2018

Increasing incidence of lentigo maligna and lentigo maligna melanoma in Catalonia.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, IRBLleida, Lleida & CIBERONC, Lleida, Spain.

Background: Recent epidemiological studies suggest that past data where superficial spreading melanoma was by far the most common subtype of melanoma may not reflect current patterns of sun exposure or other risk factors more involved in other subtypes of melanoma as lentigo maligna (LM) or lentigo maligna melanoma (LMM).

Methods: In order to measure the current situation in our country, all cases of LM and LMM diagnosed in 23 hospitals in Catalonia, from 2000 to 2007, were recorded.

Results: Although for the global period LM/LMM represented only 8. Read More

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December 2018

Pediatric tinea capitis caused by Trichophyton violaceum and Trichophyton soudanense in Rochester, Minnesota, United States.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Mayo Clinic, Rochester, MN, USA.

Background: Tinea capitis is a common pediatric dermatophyte infection. Its main pathogen in the United States is Trichophyton tonsurans accounting for greater than 95% of the infections. Other pathogens including Trichophyton violaceum and Trichophyton soudanense are common in Africa. Read More

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December 2018

Definitive radiotherapy versus Mohs surgery for early stage nonmelanoma skin cancers: a multi-institutional retrospective comparison of local recurrence.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA.

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December 2018
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Botulinum toxin type A for the treatment and prevention of hypertrophic scars and keloids: Updated review.

J Cosmet Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Botulinum Toxin Type A is a potent neurotoxin that is produced by a gram-positive bacteria clostridium botulinum. Its utilization in the treatment of various medical condition has expanded over the years in both medical and esthetic uses. It is being preferred by most physicians due to its efficacy and lack of side effects. Read More

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December 2018

What's new in the treatment of atopic dermatitis?

Dermatol Ther 2018 Nov 22:e12787. Epub 2018 Nov 22.

Department of Health Sciences, Unit of Dermatology, "Magna Graecia" University, Catanzaro, Italy.

Atopic dermatitis (AD) is a pruritic, chronic and inflammatory skin disease, with an usual onset in the pediatric age. Several drugs are used in the treatment of this skin disease. Drugs as steroid, calcineurin inhibitors, and moisturizing creams are widely used in the treatment of this disease but often patients are not satisfied with the obtained results. Read More

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November 2018
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Long-term safety and drug survival of acitretin in psoriasis: a retrospective observational study.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: This retrospective observational study aimed to investigate the long-term safety, drug survival, and factors associated with the survival of acitretin in a real-world setting.

Methods: Data of adult patients with psoriasis who attended Siriraj Hospital between 2012 and 2017 and were treated with acitretin were reviewed. Demographic data and clinical courses were recorded. Read More

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December 2018

Evidence-based skin care in preterm infants.

Pediatr Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Department of Dermatology, University of California, San Diego School of Medicine, San Diego, California.

Most guidelines on neonatal skin care emphasize issues pertaining to healthy, term infants. Few address the complex task of skin barrier maintenance in preterm, very preterm, and extremely preterm infants. Here, we provide an evidence-based review of the literature on skin care of preterm neonates. Read More

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December 2018
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Improvement of hereditary palmoplantar keratoderma with oral trametinib.

Pediatr Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Dermatology Program, Boston Children's Hospital, Boston, Massachusetts.

We report a child with a past medical history notable for congenital deafness, palmoplantar keratoderma (PPK), and hypothalamic glioma who initiated a MEK inhibitor trametinib for cancer-directed therapy at 11 years of age and was incidentally noted to have marked improvement in his PPK. Trametinib withdrawal led to worsening in the patient's PPK. We speculate that the patient's PPK improved because of trametinib, given the temporal relationship between trametinib therapy and PPK severity, observed both after introduction and withdrawal of trametinib therapy. Read More

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December 2018

Transverse melanonychia in a child receiving chemotherapy.

Pediatr Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Transverse melanonychia is a rare finding often secondary to chemotherapy, orally ingested medications, or other iatrogenic interventions. A 19-month-old boy with hemophagocytic lymphohistiocytosis treated with biweekly etoposide and dexamethasone developed transverse bands of pigment in all toenail and fingernail units consistent with transverse melanonychia. We review the literature for reported cases of transverse melanonychia and summarize suspected etiologies. Read More

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December 2018

Pulsed Dye Laser Repurposed: Treatment of Refractory Molluscum Contagiosum in Renal Transplant Patient.

Transpl Infect Dis 2018 Dec 12:e13036. Epub 2018 Dec 12.

The University of Oklahoma Health Sciences Center, College of Medicine, Department of Dermatology.

We present a case of a 15 y/o girl with an allogenic renal transplant secondary to chronic glomerulonephritis of unknown etiology who presented with treatment refractory Molluscum contagiosum of the lower extremities and perineum. Treatment of mollusca with pulse dye laser resulted in a clinically significant and sustained response. To our knowledge, this is the first report of a successful treatment of Molluscum contagiosum with pulsed dye laser in the setting of a renal transplant. Read More

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December 2018

Management of local or regional non-nodal disease.

J Surg Oncol 2018 Dec 12. Epub 2018 Dec 12.

Department of Surgery, Mayo Clinic, Rochester, Minnesota.

Some melanomas develop a striking avidity for lymphatic spread. In spite of multiple recurrences, patients can remain years without visceral metastasis. There is clearly a biologic reason for this lymphotrophic pattern of growth and dissemination, which we have yet to uncover. Read More

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December 2018

Alternate anti-leprosy therapy for "Refractory Leprosy"!

Dermatol Ther 2018 Dec 11:e12797. Epub 2018 Dec 11.

Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, Egypt.

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December 2018

Tinea faciei starting at day two of life.

Pediatr Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Children's of Alabama, Birmingham, Alabama.

Dermatophyte infections are exceedingly rare in neonates, possibly due to the thin stratum corneum and high sebum content of neonatal skin. Only a handful of cases of tinea faciei have been reported in neonates, with the majority of reports occuring in India. Here, we report what to our knowledge is the earliest reported presentation of tinea faciei in the United States. Read More

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December 2018
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Primary cutaneous CD4+ small- to medium-sized pleomorphic T-cell lymphoproliferative disorder in a pediatric patient successfully treated with low-dose radiation.

Pediatr Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Primary cutaneous CD4+ small- to medium-sized pleomorphic T-cell lymphoproliferative disorder (PCSM-LPD) is a rare and low-grade form of cutaneous T-cell proliferation with the average age of diagnosis of 54 years. Because of its rarity, the etiology or exact clinicopathology of PCSM-LPD remains unclear, with < 10 pediatric cases reported. A 13-year-old boy presented to our clinic with a raised tumor with PCSM-LPD histology and was successfully treated with ultra-low-dose radiation therapy. Read More

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December 2018

Atypical actinobacillosis affecting hind limbs and lungs in a single beef cattle herd.

J Vet Intern Med 2018 Dec 12. Epub 2018 Dec 12.

Clinic for Ruminants, Nantes, France.

Actinobacillosis usually is a sporadic infection that affects the tongue in cattle ("wooden tongue") with possible spread to the digestive tract. Two 4-year-old Rouge-des-Prés cows from a single French beef herd were referred for chronic (2-6 months) swelling and cutaneous nodules in the distal hind limbs. In addition to cutaneous signs, physical examination disclosed cachexia, lameness, lymphadenitis of the hind limbs, and pneumonia in both cows. Read More

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December 2018
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Collision tumour of extramammary Paget disease and melanoma.

Clin Exp Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

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December 2018

Keystone flap used on the legs: case series.

Clin Exp Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Hospital Clínico San Carlos, Madrid, Spain.

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December 2018

Use of essential oils: A General population survey.

Contact Dermatitis 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.

Minnesota State Fair attendees >18 years old were invited to complete a 17-question, institutional review board-approved survey on EO use. The questionnaire was designed with input by experts in contact dermatitis (EW, SH) and survey methodology (NG, EW). Read More

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December 2018