5,437 results match your criteria Dermatologica[Journal]
Dermatologica 1991 ;183(3):184-6
Department of Dermatology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Human keratinocytes are able to synthesize and express cell surface moieties characteristic of effector and/or accessory cells of the immune system (CD16, CD36, HLA-DR, intercellular adhesion molecule-1). In the present study, skin biopsies from healthy volunteers, from patients with psoriasis vulgaris (PV), mycosis fungoides (MF), purpura pigmentosa chronica (PPC), acute urticaria (AU) and from positive tuberculin skin tests were investigated with regard to the reactivity with the monoclonal antibodies to complement receptors CR1 CR2 and CR3 by means of a multistep immunoperoxidase method. In the clinically involved skin of all patients with PV, MF or PPC, and in biopsies obtained from positive tuberculin tests, specific epidermal intercellular staining with OKB7 and Leu anti-CR2 was seen on subcorneal keratinocytes. Read More
Dermatologica 1991 ;182(2):98-106
Unité de Dermatologie professionnelle et de l'Environnement, Université Catholique de Louvain, Brussels, Belgium.
Atopic dermatitis (AD) can be exacerbated by contact with airborne allergens, amongst which Dermatophagoides pteronyssinus (Dpt) appears to be potentially important. Specific IgE antibodies towards Dpt are often found in AD, and it can therefore be speculated that suppression of the production of anti-Dpt IgE might result in a significant clinical improvement. Complexes of antigen and specific antibodies have been shown to suppress the production of antibody in other systems; we report here the evaluation in an open trial of the capacity of such complexes to improve symptoms of AD. Read More
Dermatologica 1991 ;182(2):94-7
Department of Dermatology, School of Medicine, Chiba University, Japan.
Nodular xanthomas on both elbows and a streak-like xanthoma on the intergluteal area developed in a 4-year-old girl with type IIa hyperlipoproteinemia. She had no disease associated with secondary hypercholesterolemia and no family history of hypercholesterolemia. Her xanthomas regressed under fat restriction diet and cholestyramine therapy. Read More
Dermatologica 1991 ;182(2):89-93
Department of Dermatology, University of Pavia, Italy.
The role of race in modulating skin responses has been investigated. Several parameters (skin thickness, transepidermal water loss, water content of the stratum corneum and skin biomechanics) have been measured using noninvasive tools in whites, Hispanics and blacks to assess whether the melanin content could induce changes in skin biophysical properties. Marked differences between races appear in stratum corneum water content and in skin extensibility, recovery and elastic modulus. Read More
Dermatologica 1991 ;182(2):81-4
Department of Dermatology, University of Erlangen-Nürnberg, FRG.
Macroscopic discrimination between amelanotic malignant melanoma (aMM) and the so-called granuloma pyogenicum (GP) is often uncertain since reliable criteria for a clear differentiation of either growth are lacking. In a search of such criteria we analysed the data of 57 consecutive in-patients with cutaneous aMM and of 83 with GP presenting at our Department during the years 1970-1988. The following items were compared with each other: duration from growth onset to definite diagnosis, site of growth, age and sex of the patients. Read More
Dermatologica 1991 ;182(2):77-80
Department of Dermatology, University Hospital Zurich, Switzerland.
We describe 9 patients who presented Becker's nevus (BN) together with a malignant melanoma (MM). Eight patients were male. In 5 patients the MM was on the same body site as the BN. Read More
Dermatologica 1991 ;182(2):73-6
Department of Dermatology, Stanford University School of Medicine, Calif.
This review focuses on dermatoses that are caused by the presence of sweat--a previously underemphasized subject. A working classification based on 'internal sweating' (extravasated sweat in the dermis and epidermis) and 'external sweating' (sweat on skin surface) is proposed. Clinical observations suggest that transient acantholytic dermatosis is the consequence of extravasated sweat; we speculate that it is an example of sweat-related, protease-induced epidermal acantholysis. Read More
Dermatologica 1991 ;182(2):71-2
Dermatologica 1991 ;182(2):135-7
Department of Dermatology, Medical College of Wisconsin, Milwaukee.
Kaposi's sarcoma (KS) is an important finding in patients infected with human immunodeficiency virus (HIV), with a distinctive spectrum of clinical presentations. Three cases of dermatophytosis in HIV-infected patients are presented which clinically mimic the appearance of KS. This new observation underscores the importance of histopathologic examination in the evaluation of skin lesions suspicious for the diagnosis of KS. Read More
Dermatologica 1991 ;182(2):128-31
Department of Dermato-Venereology, Bavarian Julius-Maximilians University, Würzburg, FRG.
We present the case of a 77-year-old female with a rare genital and anoperineal granulomatous cutaneous manifestation resembling cheilitis granulomatosa Miescher. The typical histological findings of epithelioid cell granulomas were localized in the vulva and anoperineal region; the latter manifestation has not yet been described. Based on our personal observations and a review of the literature, the clinical and histological features of vulvitis granulomatosa are described. Read More
Dermatologica 1991 ;182(2):124-7
Department of Dermatology, Free University of Brussels, Belgium.
Hair casts are small cylindrical structures, encircling individual scalp hairs but easily movable along the involved hair shafts. This hair disorder of unknown pathogenesis is only rarely mentioned in the dermatologic literature. We report the case of a 5-year-old girl, who has been treated during 2 years for pediculosis capitis. Read More
Dermatologica 1991 ;182(2):121-3
Department of Internal Medicine, Ramón y Cajal Hospital, Madrid, Spain.
A patient with severe Raynaud's phenomenon (RP) associated with the presence of antibodies against extractable nuclear antigen (ribonucleoprotein) in the context of undifferentiated connective tissue syndrome is presented. The rapid course of digital necrosis in her case resulted in the surgical amputation of 9 of her fingers. We conclude that massive digital necrosis accompanied by severe RP could constitute the first manifestation of a connective tissue disease. Read More
Dermatologica 1991 ;182(2):112-4
Department of Dermatology, University Hospital Nijmegen, The Netherlands.
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare and chronic skin disorder, which may trouble the patient considerably. The condition is generally believed to be resistant to therapy, although some authors have reported success with several treatments. including dithranol and etretinate. Read More
Dermatologica 1991 ;182(2):107-11
Department of Dermatology, Hôpital cantonal, University of Geneva, Switzerland.
Dermo-epidermal atrophy is one of the main side effects of long-term treatment with topical corticosteroids. Retinoic acid may prevent and even reverse these effects in animals. Extension of this concept to therapy in humans implies that several studies have been performed; among others, it has to be established that treatment with topical retinoic acid does not interfere with the anti-inflammatory action of topical corticosteroids. Read More
Dermatologica 1991 ;182(1):7-11
Division of Allergy, Dermatology Clinic, University Hospital, Zurich, Switzerland.
The hyper-IgE syndrome is characterized clinically by recurrent staphylococcal abscesses of the skin, lungs and other sites from infancy. Affected patients also have a pruritic dermatitis that differs in character and distribution from lesions of atopic dermatitis. Most lack other signs of atopic disease, develop persistent pneumatoceles and have osteopenia. Read More
Dermatologica 1991 ;182(1):67
Dermatologica 1991 ;182(1):66
Dermatologica 1991 ;182(1):65-6
Dermatologica 1991 ;182(1):65
Dermatologica 1991 ;182(1):63-4
Department of Medical Surgery Dermatology and Venereology, Faculty of Medicine, University Hospital, Sevilla, Spain.
The published 9th case of circumscribed pilary dysembryoplasia of the palms is presented. Differences between this case and Becker's pigmented hair nevus, congenital smooth muscle hamartoma, circumscribed acquired hypertrichosis and pigmented nevus are discussed. Read More
Dermatologica 1991 ;182(1):59-62
Department of Dermatology, Hirosaki University School of Medicine, Japan.
A 76-year-old man with multiple erythematous lesions on his palms and soles which appeared following bullous pemphigoid (BP) is the subject of this case report. The lesions were not raised above the normal skin level, and there were no nodules on the erythematous lesions. The lesions had the histologic appearance of eccrine syringofibroadenoma. Read More
Dermatologica 1991 ;182(1):56-8
Servicio de Dermatologia, Unidad Docente de la UB, Hospital Sagrado Corazón-QSA, Barcelona, España.
A patient with Sjögren's syndrome and seronegative polyarthritis is reported. After piroxicam intake and sun exposure she developed subacute cutaneous lupus erythematosus lesions with Ro antibodies. Despite drug withdrawal, typical cutaneous lesions and serological markers of systemic lupus erythematosus (SLE) progressively appeared. Read More
Dermatologica 1991 ;182(1):52-5
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
We report a case of urticaria pigmentosa, acromegaly and acanthosis nigricans in a 25-year-old male. The patient exhibited multiple pigmented papules on the trunk and the extremities. Histological examinations of the papules revealed infiltrates of mast cells in the upper dermis. Read More
Dermatologica 1991 ;182(1):47-51
Department of Dermatology, University of Turin, Italy.
A case of papillary eccrine adenoma of the thigh of a 63-year-old woman is reported. Histologically, the tumor was composed of cystic dilated and branching tubular structures with papillary projections into the lumen, surrounded by a fibrous stroma. In addition, in some areas it was composed almost exclusively of solid strands of epithelial cells. Read More
Dermatologica 1991 ;182(1):39-42
Department of Dermatology, University Hospital, Utrecht, The Netherlands.
Extravasation is a frequent complication associated with intravenous infusions. Two case histories are reported in which blister formation is one of the most striking features after the accident. The infusion fluids are no vesicants but commonly used intravenous infusion fluids. Read More
Dermatologica 1991 ;182(1):35-8
Department of Dermatology, Heinrich Heine University, Düsseldorf, FRG.
Three patients with solar urticaria were treated with plasmapheresis. By intradermal injection of in vitro irradiated serum the existence of a circulating photoallergen was demonstrated in cases 1 and 2 but not in case 3. Plasmapheresis induced complete remission of solar urticaria in case 1 and transient improvement in case 2. Read More
Dermatologica 1991 ;182(1):27-31
Chair of Terapia Medica Sistematica, University of Modena, Italy.
The aim of this paper is to evaluate invasive and non-invasive indices of iron store and compare the effectiveness of different ferrodepletive protocols in 150 patients with porphyria cutanea tarda (PCT). Iron removal was performed either by intensive phlebotomy (22 cases) or slow subcutaneous and high intravenous doses of desferrioxamine (18 and 5 cases, respectively), and several laboratory parameters were studied; among these, oligo-elements and urinary porphyrins (detected by HPLC) were taken into account before and after the treatments. Serum iron, transferrin saturation, ferritin (RIA) and nuclear magnetic resonance results were compared with invasive findings in order to detect the metal deposition in liver tissue (atomic absorption concentration, optic or electron-microscopic detection). Read More
Dermatologica 1991 ;182(1):18-22
Clinica Dermatologica II, Università degli Studi di Firenze, Italia.
Biopsies taken from vulvar lesions in 12 women affected by vulvar lichen sclerosus et atrophicus (LSA) have been processed for immunohistological study. Activated (HLA-Dr+) T cells, associated with CD1a+ accessory cells, were found in the dermis in all cases, with architectural patterns varying in relation to the histological phase (early, well developed, old) of the lesion. Interestingly, the number of epidermal CD1a+ Langerhans cells (LCs) was increased in all cases, without any correlation with the amount of the dermal infiltrate and with the histological phase of the lesions. Read More
Dermatologica 1991 ;182(1):1-6
Department of Dermatology, University of Pavia, IRCCS Policlinico S. Matteo, Italy.
Cutaneous changes induced by aging can be quantified and monitored noninvasively by means of bioengineering tools. Skin elasticity, hydration, skin blood flow and skin surface pattern show age-related changes reflecting the damage of cutaneous structures involved. Impairment and degeneration of elastic and collagen networks are responsible for the progressive decrease in skin elasticity recorded during aging. Read More
Dermatologica 1991 ;182(2):132-4
Cutaneous Pathology, St. John's Mercy Medical Center, St. Louis, Mo.
A cutaneous mastocytoma with associated histologic features of eosinophilic cellulitis is reported. The tumor occurred as a small, asymptomatic lesion on the left thigh of a 4-year-old boy. Microscopically, an accumulation of mast cells, microgranulomas, eosinophils and 'flame figures' was present. Read More
Dermatologica 1991 ;182(1):32-4
Department of Dermatology, Ludwig Maximilian University, Munich, FRG.
According to an opinion shared by many, human axillary and inguinal odour is related to short-chain fatty acids produced by gram-positive bacteria. Especially coryneform bacteria are said to produce these odiferous substances. After sampling 22 different strains of coryneform bacteria we cultured them for 48 h in a rich medium. Read More
Dermatologica 1991 ;182(1):23-6
Department of Dermatology, University of Erlangen-Nürnberg, FRG.
In both, 6 hyperthyroid and 6 hypothyroid patients as well as 10 healthy volunteers, cell cycle kinetics of dissected anagen scalp hair bulbs were determined by means of DNA flow cytometry (DNA-FCM). Compared with the healthy control group in patients with thyroid disorders striking differences of cell kinetic data were evaluated. In hyperthyroidism a significant increase (30%) and in hypothyroidism a significant decrease (15%) of S and G2+M phase cell percentages was found. Read More
Dermatologica 1991 ;182(4):253
Dermatologica 1991 ;182(4):252-3
Dermatologica 1991 ;182(4):250-1
Department of Dermatology, Indiana University School of Medicine, Indianapolis.
Dermatologica 1991 ;182(4):247-9
Department of Dermatology, University of Bologna, Italy.
We report on a 4 1/2-year-old girl affected by loose anagen hair and Noonan's syndrome. The girl had short, blond, easily pluckable hair that had never been cut. The trichogram showed an absolute prevalence of abnormally shaped anagen bulbs lacking inner and outer root sheaths. Read More
Dermatologica 1991 ;182(4):243-6
First Department of Dermatology, University of Milan, Italy.
We report a case of prurigo nodularis of Hyde as the presenting sign of Hodgkin's disease in a 22-year-old girl. Though pruritus is a common symptom of Hodgkin's disease, prurigo nodularis has rarely been reported as a Hodgkin's symptom. Read More
Dermatologica 1991 ;182(4):235-8
Institute of Dermatology, United Medical School, St. Thomas' Hospital, London, UK.
We report a patient with generalized recessive dystrophic epidermolysis bullosa (RDEB) who developed 3 squamous cell carcinomas. The tumours appeared simultaneously at acral sites on both upper limbs and were poorly differentiated. Despite surgery and radiotherapy the patient died from metastatic disease within 6 months of presentation. Read More
Dermatologica 1991 ;182(4):233-4
Department of Dermatology, University of Genoa, Italy.
A patient with an unusual form of follicular impetigo, who later developed classical systemic lupus erythematosus (SLE) is described. When she had pyoderma, direct immunofluorescence and serology already suggested a connective tissue disease. Pyoderma could have been the presenting manifestation of SLE. Read More
Dermatologica 1991 ;182(4):231-2
Department of Dermatology, Free University Hospital, Amsterdam, The Netherlands.
We report on a case of solar urticaria with elevated protoporphyrin in the stool. No other evidence for an erythropoietic protoporphyria could be found. Read More
Dermatologica 1991 ;182(4):225-30
Department of Dermatology, Chiba University School of Medicine, Japan.
Nine patients with chronic stable psoriasis (4 males and 5 females) were entered in this trial. Eicosapentaenoic acid (EPA) ethylester (90% pure) without docosahexaenoic acid (DHA) in gelatin-coated capsules at a daily dose of 3.6 g was administered to 9 patients for 3 months, 7 patients for 6 months and 6 patients for 12 months. Read More
Dermatologica 1991 ;182(4):218-20
Clinica Dermatologica dell'Università di Pavia, Italia.
59 patients suffering from vitiligo were investigated anamnestically and clinically with intradermal (prick tests) and laboratory tests (RAST and total IgE count) for the presence of atopy. Clinical manifestations (allergic rhinitis, asthma) and intense positive prick tests and RAST with an increase in total IgE count were found in 13 patients (22%). This frequency was significantly higher than that found in the normal population in our area (11. Read More
Dermatologica 1991 ;182(4):211-3
Department of Dermatopathology, University of Liège, Belgium.
We studied by the Sebutape technique variations in the sebum excretion and in the number of active sebaceous glands during 3 consecutive menstrual cycles. In seborrheic women we found cyclic changes with a maximum sebum excretion during the week before menstruation. In women with a low sebum production, no changes were found. Read More
Dermatologica 1991 ;182(4):207-10
Department of Dermatology, Tel-Aviv Sourasky Medical Center, Ichilov Hospital, Israel.
112 cases of induced pemphigus were reviewed. The causative drugs were divided into three groups according to their chemical structure, and the clinical, prognostic and laboratory characteristics were analyzed and compared. Our literature screening indicates that the biological progress and clinical course of the disease depend upon the type of the inducing/triggering drug in the majority of patients. Read More
Dermatologica 1991 ;182(3):205
Dermatologica 1991 ;182(3):204-5
Dermatologica 1991 ;182(3):199-202
Department of Dermatology, University of Düsseldorf, FRG.
A 57-year-old man suffering from persistent light reaction with photocontact allergy to musk ambrette and contact allergy to fragrance mix was evaluated. A lowered minimal erythema dose to UV-B (MED-UV-B) was seen. Reactions to long-wave UV-A and visible radiation were normal. Read More
Dermatologica 1991 ;182(3):193-5
Dermatology, UMDNJ-New Jersey Medical School, Newark.
Verrucous carcinoma of the skin is a rare cancer which tends to appear on the soles of the feet, although it can appear elsewhere on the cutaneous surface. It has not, to our knowledge, been previously reported on a leg amputation stump. Read More
Dermatologica 1991 ;182(3):188-90
Department of Dermatology, Saiseikai Utsunomiya Hospital, Japan.
An 11-year-old girl with Turner's syndrome developed a combined nevus on the back. The examination of the excised specimen revealed the combination of common compound nevus and a component of Spitz's nevus. Numerous melanocytic nevi are a feature of Turner's syndrome, but this appears to be the first case of a combined nevus with Spitz's component. Read More