1,489 results match your criteria Dermatologic Therapy[Journal]


Fluorescence-Advanced Videodermatoscopy: A promising and potential technique for the in vivo evaluation of vitiligo.

Dermatol Ther 2019 Feb 14:e12863. Epub 2019 Feb 14.

Division of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1111/dth.12863DOI Listing
February 2019

Infective endocarditis in two patients with pemphigus vulgaris under multiagent immunosuppressive drug therapy: a rare entity to remember in the differential diagnosis of fever of unknown origin.

Dermatol Ther 2019 Feb 13:e12860. Epub 2019 Feb 13.

Department of Dermatology and Venereology, Istanbul Faculty of Medicine, Istanbul University, Istanbul.

Pemphigus vulgaris (PV) is an autoimmune blistering skin disease that, may require multiagent immunosuppressive drug therapies in severe cases. In addition to the well established corticosteroid sparing agents azathioprine, mycophenolate mofetil, and methotrexate, rituximab is being increasingly used alone or in combination in the management of PV. Due to the chronic course of the disease, the cumulative effects of these therapy agents over long follow-up periods may result in various adverse reactions, including bacterial and viral infections. Read More

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http://dx.doi.org/10.1111/dth.12860DOI Listing
February 2019

Efficacy and safety of secukinumab in a psoriatic patient affected by comorbid metabolic disorders.

Dermatol Ther 2019 Feb 13:e12858. Epub 2019 Feb 13.

Dermatology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1111/dth.12858DOI Listing
February 2019

Treatment of Injection-Induced Ecchymoses with Light/Laser-Assisted Technology.

Dermatol Ther 2019 Feb 13:e12861. Epub 2019 Feb 13.

Maxillo Facial Surgery, University of Verona, Italy.

An increasing number of minimally invasive cosmetic procedures, such as filler or botulinum toxin injections, are performed annually. These procedures are associated with a high risk of post-procedure bruising or ecchymosis. Ecchymoses arise following hemorrhage and extravasation of red blood cells into the subcutaneous tissue, leading to local skin discoloration. Read More

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http://dx.doi.org/10.1111/dth.12861DOI Listing
February 2019

Syphilis with Charcot arthropathy: a case report.

Dermatol Ther 2019 Feb 13:e12862. Epub 2019 Feb 13.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.

Syphilis is a chronic systemic infectious disease involving multiple organs. Involvement of skeletal system by syphilis including osteochondritis, osteoarthritis, periostitis and osteitis. Charcot arthropathy is an unusual concomitant disease of syphilis, and the incidence had decreased significantly these decades. Read More

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http://dx.doi.org/10.1111/dth.12862DOI Listing
February 2019

Intravenous immunoglobulin treatment: Where do dermatologists stand?

Authors:
Selma Emre

Dermatol Ther 2019 Feb 13:e12854. Epub 2019 Feb 13.

Department of Dermatology, Yildirim Beyazit University, Medical School, Ankara, Turkey.

Intravenous immunoglobulins are therapeutic products, comprising polyclonal IgGs, which are obtained from human plasma pool of healthy blood donors. Despite the lack of FDA approval, the experience of using IVIG in various dermatological diseases increases day by day and exciting results are reported. However, experience with the use of IVIG in dermatological indications are mostly case reports whereas randomized, controlled, double-blind, multicentric studies have not been performed. Read More

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http://dx.doi.org/10.1111/dth.12854DOI Listing
February 2019

Infliximab improved the refractory cutaneous involvement in a patient with dermatomyositis.

Dermatol Ther 2019 Feb 12:e12859. Epub 2019 Feb 12.

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1111/dth.12859DOI Listing
February 2019
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How reflectance confocal microscopy can help diagnose an enigmatic variant of dermatofibroma.

Dermatol Ther 2019 Feb 12:e12857. Epub 2019 Feb 12.

Dermatology Unit, Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1111/dth.12857DOI Listing
February 2019

Capecitabine-induced eruptive acral hyperpigmentation: clinical and dermoscopic evaluation of two cases.

Dermatol Ther 2019 Feb 12:e12853. Epub 2019 Feb 12.

Dermatology Unit, University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1111/dth.12853DOI Listing
February 2019

New therapeutic options in the management of superficial fungal diseases.

Dermatol Ther 2019 Feb 12:e12855. Epub 2019 Feb 12.

Ataturk Training and Research Hospital, Dermatology Clinic, Ankara, Turkey.

Superficial fungal infections which effect the skin, hair, and nails, are widely observed in the world. Causative agents are Candida species, dermatophytes, and Malassezia species. In recent years new antifungal agents and formulations have been developed for these infections. Read More

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http://dx.doi.org/10.1111/dth.12855DOI Listing
February 2019

Psoriasis with a dirt-adherent: A Rare Case Report.

Dermatol Ther 2019 Feb 12:e12856. Epub 2019 Feb 12.

Departmengt of Dermatology, No.1 Hospital of China Medical University.

Cutaneous dirt-adherent disease (CDAD) is a rare psychogenic dermatosis mainly occurring in young Japanese and Chinese women. It mainly occurs on cheeks, forehead, nipple, mammary areola and around mammary areola. To our knowledge, this is the first case of CDAD with the skin lesion of psoriasis rupioides to be reported. Read More

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http://dx.doi.org/10.1111/dth.12856DOI Listing
February 2019

Multiple paradoxical reactions during ixekizumab therapy.

Dermatol Ther 2019 Feb 12:e12852. Epub 2019 Feb 12.

Institute of Dermatology, Catholic University - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

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http://doi.wiley.com/10.1111/dth.12852
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February 2019
5 Reads

Unsatisfactory response to sirolimus in Maffucci syndrome-associated spindle cell hemangiomas.

Dermatol Ther 2019 Feb 5:e12851. Epub 2019 Feb 5.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/dth.12851DOI Listing
February 2019

Huge rhinophyma in a complicated patient successfully treated with C02 laser.

Dermatol Ther 2019 Feb 3:e12850. Epub 2019 Feb 3.

Section of Dermatology, University of Parma, Parma, Italy.

Rhinophyma is a bothersome and disfiguring condition of the nose that is often cause of cosmetic embarrassment and social reclusion. Nowadays the therapeutic possibilities are highly variable and have to be personalized case by case. These possibilities include pharmacological therapy, laser surgery, mechanical dermabrasion and surgical excision. Read More

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http://dx.doi.org/10.1111/dth.12850DOI Listing
February 2019
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Tetra-arsenic tetra-sulfide ameliorates lupus syndromes by inhibiting IL-17 producing double negative T cells.

Dermatol Ther 2019 Feb 1:e12849. Epub 2019 Feb 1.

Department of Dermatology, People's Hospital of Peking University, Beijing, China.

Systemic lupus erythematosus (SLE) is an autoimmune disease of uncertain etiology that affects multiple tissues and organs. Tetra-arsenic tetra-sulfide (As S ), a traditional Chinese medicine, is effective on acute promyelocytic leukemia with mild side effects. In our previous study, BXSB lupus-prone mice treated with As S has showed improved monocytosis, decreased serum interleukin (IL)-6 and suppressed skin, liver and renal lesions with well-tolerance. Read More

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http://dx.doi.org/10.1111/dth.12849DOI Listing
February 2019
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The Efficacy of Omalizumab in Cutaneous Mastocytosis: A Case Series.

Dermatol Ther 2019 Jan 29:e12848. Epub 2019 Jan 29.

Center for Clinical Studies, Houston, Texas.

Background: Mastocytosis describes a heterogeneous group of disorders arising from a clonal proliferation of mast cells. Given the lack of curative treatments for the cutaneous form, there is a significant need for superior therapies. Omalizumab is a recombinant DNA-derived humanized IgG monoclonal antibody that selectively binds to human immunoglobulin E (IgE). Read More

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http://doi.wiley.com/10.1111/dth.12848
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http://dx.doi.org/10.1111/dth.12848DOI Listing
January 2019
2 Reads

Effectiveness and safety of switching to biosimilar infliximab and etanercept in patients with psoriasis.

Dermatol Ther 2019 Jan 29:e12846. Epub 2019 Jan 29.

Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.

Real-life data on the effectiveness and safety of biosimilar and biologic drugs licensed for treatment of psoriasis is lacking. We retrospectively analysed patient records from 69 patients with moderate to severe psoriasis treated at the department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark in the period March 1st 2015 to October 1st 2017 who were administratively switched from the anti-TNF biologics infliximab (Remicade) and etanercept (Enbrel) to the biosimilars Remsima and Benepali, respectively. Approximately 25% of patients treated with infliximab and approximately 40% of patients treated with etanercept reported a worse effect after being switched from the original drug to its biosimilar. Read More

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http://dx.doi.org/10.1111/dth.12846DOI Listing
January 2019

Two cases of Hidradenitis suppurativa and botulinum toxin type a therapy: A novel approach for a pathology that is still difficult to manage.

Dermatol Ther 2019 Jan 28:e12841. Epub 2019 Jan 28.

Dermatology Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, Italy.

Hidradenitis suppurativa is a chronic skin disease with an intense inflammatory activation. It typically affects the intertriginous areas with cysts, fistulae, and scarring extremely painful. Patients suffer from severe psychological impact. Read More

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http://dx.doi.org/10.1111/dth.12841DOI Listing
January 2019

THE ANALYSIS OF THE THERAPEUTIC POTENTIAL OF USTEKINUMAB IN PSORIASIS VULGARIS TREATMENT.

Dermatol Ther 2019 Jan 28:e12843. Epub 2019 Jan 28.

Department of Molecular Biology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia.

The molecular mechanism of ustekinumab action involves an interruption of signaling pathways activated by IL-12/23. The aim of this paper was to evaluate the efficacy of the anti-IL12/23 therapy in 7 psoriatic patients by assessing changes in the values of PASI, DLQI, BSA indexes, and an analysis of changes in the mRNA expression profile of genes IL12A, IL12B, IL23A during three 40-week long observation periods. The clinical (PASI, DLQI, BSA indexes) and molecular (RTqPCR for IL12A, IL12B, IL23A) analyses were performed on the day of ustekinumab therapy initiation, 4 weeks post first administration, and every 12 weeks thereafter. Read More

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http://dx.doi.org/10.1111/dth.12843DOI Listing
January 2019
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Clinical experiences on alopecia areata treatment with tofacitinib: A study of 63 patients.

Dermatol Ther 2019 Jan 28:e12844. Epub 2019 Jan 28.

Department of Dermatology, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey.

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http://dx.doi.org/10.1111/dth.12844DOI Listing
January 2019
2 Reads

Erythema multiforme: Differences between HSV-1 and HSV-2 and management of the disease-A case report and mini review.

Dermatol Ther 2019 Jan 28:e12847. Epub 2019 Jan 28.

Department of Dermatology, Sapienza University of Rome, Sant'Andrea General Hospital, Rome, Italy.

Erythema multiforme (EM) is an immune-mediated reaction characterized by target lesions and with possible mucosal involvement. Its most frequent cause is HSV, with HSV-1 more common than -2. It is usually self-limited but it can show recurrences. Read More

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http://dx.doi.org/10.1111/dth.12847DOI Listing
January 2019

Treatment resistant impetigo herpetiformis treated with infliximab.

Dermatol Ther 2019 Jan 28:e12839. Epub 2019 Jan 28.

Department of Pathology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Impetigo herpetiformis is a rare disease of pregnancy with the onset being in the second half of pregnancy and resolution after delivery. It is associated with a high rate of perinatal mortality and fetal abnormalities. Clinical and histological features of the disease are consistent with pustuler psoriasis. Read More

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http://doi.wiley.com/10.1111/dth.12839
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January 2019
3 Reads

Complete resolution of cutaneous larva migrans with topical ivermectin: A case report.

Dermatol Ther 2019 Jan 28:e12845. Epub 2019 Jan 28.

Dermatology Unit, NESMOS Department, S. Andrea Hospital, University of Rome "Sapienza", Rome, Italy.

Cutaneous larva migrans (CLM; also called creeping eruption) is a cutaneous ectoparasitosis commonly observed in tropical countries. It is characterized by an erythematous, pruritic, and raised lesion with linear or serpiginous distribution, typically localized at the lower extremities. Oral ivermectin represents the most recommended current treatment, with important adverse effects associated. Read More

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http://dx.doi.org/10.1111/dth.12845DOI Listing
January 2019

Current and Emerging Therapies for Hand Eczema.

Dermatol Ther 2019 Jan 28:e12840. Epub 2019 Jan 28.

Division of Dermatology, Department of Medicine, University of Arizona, Tucson, AZ.

Purpose: Though hand eczema (HE) and chronic hand eczema (CHE) are common conditions with significant disease burden, they traditionally have had limited treatment options beyond topical and short-term systemic corticosteroids. We reviewed published and preliminary evidence on the current and emerging topical and systemic therapeutic agents for HE and CHE. The etiologies of various HE subtypes are discussed, and remaining knowledge and practice gaps are highlighted to encourage further investigations. Read More

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http://dx.doi.org/10.1111/dth.12840DOI Listing
January 2019
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Development of herpes zoster during infliximab treatment for pediatric generalized pustular psoriasis: A case report.

Dermatol Ther 2019 Jan 23:e12838. Epub 2019 Jan 23.

Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.

The present authors report a 12-year-old Chinese child with generalized pustular psoriasis who was responded well to infliximab, but an adverse effect of herpes zoster occurred after the first infusion soon. The antiviral treatment was effective and no recurrence or flaring was observed after half-year of follow-up. This case reminds us to highlight the risk of viral infection during biological treatment on patients with psoriasis or autoimmune disease. Read More

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http://dx.doi.org/10.1111/dth.12838DOI Listing
January 2019
8 Reads

PLATELET RICH PLASMA IN ANDROGENETIC ALOPECIA: A SYSTEMATIC REVIEW.

Dermatol Ther 2019 Jan 22:e12837. Epub 2019 Jan 22.

Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine - Miami, FL, USA.

In recent years, dozens of manufacturers and clinics have been promoting the use of platelet rich plasma (PRP) procedures for skin and hair regeneration. Well-designed randomized controlled studies for these procedures are lacking. In this communication, we review the efficacy and safety of PRP procedures for androgenetic alopecia from multiple published peer-reviewed studies. Read More

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http://dx.doi.org/10.1111/dth.12837DOI Listing
January 2019
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Low dose isotretinoin as an adjuvant therapy for treatment of different clinical variants of warts: A case series.

Dermatol Ther 2019 Jan 21:e12836. Epub 2019 Jan 21.

Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, Egypt.

Warts constitute the most frequently observed dermatological manifestations of human papillomavirus (HPV). Although an extensive range of treatments exist for local warts, there is no specific therapy based on high-quality evidence of notable treatment success or high cure rate, or minimal adverse effects. Recalcitrant warts are, therefore, a common therapeutic problem. Read More

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http://doi.wiley.com/10.1111/dth.12836
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http://dx.doi.org/10.1111/dth.12836DOI Listing
January 2019
10 Reads

Impressive response of CD30-negative, treatment-refractory mycosis fungoides to brentuximab vedotin.

Dermatol Ther 2019 Jan 19:e12835. Epub 2019 Jan 19.

Department of Dermatology, University of Minnesota, Moffitt Cancer Center, Tampa, Florida.

Brentuximab vedotin is a CD30-antibody/drug conjugate which has demonstrated excellent response in treating CD30-positive mycosis fungoides (MF) and anaplastic large cell lymphoma (ALCL). In this report, we present a patient with CD30-negative MF refractory to multiple other lines of therapy who demonstrated a dramatic response to brentuximab. This paradoxical response may be due to inadequate detection of CD30 expression by immunohistochemical techniques. Read More

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http://dx.doi.org/10.1111/dth.12835DOI Listing
January 2019
2 Reads

"Intramatricial Platelet Rich Plasma Therapy: A Novel Treatment Modality in Refractory Nail Disorders".

Dermatol Ther 2019 Jan 18:e12831. Epub 2019 Jan 18.

Department of Dermatology & STD, NDMC Medical College & Hindu Rao Hospital, New Delhi, India.

Background: Platelet rich plasma (PRP) is essentially an increased concentration of autologous platelets (growth factors) suspended in small amount of plasma. These factors have a proliferative and regenerative effect on a number of tissues in body and have been extensively used in dermatology, surgery, orthopedics and dentistry.

Case Report: Two patients, one with nail lichen striatus and second with idiopathic trachyonychia were treated with intramatriceal injections of platelet rich plasma. Read More

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http://dx.doi.org/10.1111/dth.12831DOI Listing
January 2019
2 Reads

Acitretin Combined with NB-UVB in the Treatment of Cutaneous CD30-positive Anaplastic Large Cell Lymphoma.

Dermatol Ther 2019 Jan 18:e12834. Epub 2019 Jan 18.

Department of Dermatology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Cutaneous CD30 lymphoproliferative disorders represent a spectrum of skin lymphatic reticular proliferative diseases, including lymphomatoid papulosis (LYP), primary cutaneous anaplastic large cell lymphoma (PC-ALCL), and borderline lesions between them. Although they all express CD30 as a phenotypic marker and share overlapping immunophenotypic features, they differ in clinical manifestations, pathological features, treatment, and prognosis. LYP is a kind of benign disease characterized by recurrent papules and nodules and may spontaneously regress. Read More

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http://dx.doi.org/10.1111/dth.12834DOI Listing
January 2019
2 Reads

Successful treatment of porocarcinoma with maxacalcitol and imiquimod.

Dermatol Ther 2019 Jan 18:e12830. Epub 2019 Jan 18.

Department of Dermatology, Toho University Ohashi Medical Center, Tokyo, Japan.

This is the first report of a case of porocarcinoma that was successfully treated with maxacalcitol and imiquimod. Read More

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http://doi.wiley.com/10.1111/dth.12830
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http://dx.doi.org/10.1111/dth.12830DOI Listing
January 2019
4 Reads

"Change over time in the treatment of pemphigus vulgaris between 2004 and 2016 in Iran": A multiple cross-sectional study.

Dermatol Ther 2019 Jan 18:e12827. Epub 2019 Jan 18.

Department of Dermatology, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/dth.12827DOI Listing
January 2019
2 Reads
1.478 Impact Factor

Kaposi varicelliform eruption induced by methotrexate in an adult atopic dermatitis patient.

Dermatol Ther 2019 Jan 18:e12826. Epub 2019 Jan 18.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1111/dth.12826DOI Listing
January 2019
1 Read

Omalizumab as an alternative therapeutic tool in the treatment of bullous pemphigoid: A case report.

Dermatol Ther 2019 Jan 18:e12829. Epub 2019 Jan 18.

Dermatology and Venereology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain.

Bullous pemphigoid (BP) is an acquired autoimmune bullous disease characterized by autoantibodies against the hemidesmosomal proteins found in the basal keratinocytes of the basement membrane zone (BMZ): a 180 kDa protein (type XVII collagen) mainly and the 230 kDa antigen. There is such evidence that the antibodies against the BMZ components are not only of IgG type, but also this bullous disease may have IgE antibodies directed to the BMZ that contribute to the pathogenesis of the disorder. IgE is not only thought to contribute to the pathogenesis of BP, it has also been suggested that eosinophils play a role in the development of the first signs associated with BP. Read More

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http://dx.doi.org/10.1111/dth.12829DOI Listing
January 2019
2 Reads

Scalp basal cell carcinoma: A different entity?

Dermatol Ther 2019 Jan 18:e12828. Epub 2019 Jan 18.

Department of Pathology, Faculty of Medicine of the University of Porto, Porto, Portugal.

Basal cell carcinoma is the most frequent malignant neoplasm in white-skinned individuals. It develops in different body areas, including in the scalp, which is a unique anatomical region due to the high number of pilosebaceous follicles; the scalp is protected from UV exposure, a main risk factor for basal cell carcinoma development. Moreover, scalp basal cell carcinoma has been described as more aggressive and difficult to treat than other forms of basal cell carcinoma. Read More

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http://dx.doi.org/10.1111/dth.12828DOI Listing
January 2019
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A case of pityriasis lichenoides et varioliformis acuta pemphigoides successfully treated with methotrexate and corticosteroids.

Dermatol Ther 2019 Jan 19:e12833. Epub 2019 Jan 19.

Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.

Pityriasis lichenoides et varioliformis acuta (PLEVA) pemphigoides is an uncommon skin disease, which is characterized by the appearance of blistering skin lesions in patients with PLEVA. We present a 3-year-old boy, who was diagnosed with PLEVA pemphigoides. Combined treatment of oral methotrexate and corticosteroids was more effective than corticosteroids alone on this patient. Read More

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http://dx.doi.org/10.1111/dth.12833DOI Listing
January 2019
5 Reads

Rapid remission of Stevens-Johnson syndrome by combination therapy using etanercept and intravenous immunoglobulin and a review of the literature.

Dermatol Ther 2019 Jan 18:e12832. Epub 2019 Jan 18.

Department of Dermatology, Peking University First Hospital, Beijing, China.

SJS/TEN are spectrum of rare, acute and life-threatening delayed-type drug hypersensitivity reactions that are associated with high mortality rates. However, no therapeutic standard has been proposed for SJS/TEN. Here, we report a case of a patient diagnosed with Stevens-Johnson syndrome whose disease progression was halted by a single dose of etanercept and was treated successfully. Read More

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http://doi.wiley.com/10.1111/dth.12832
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http://dx.doi.org/10.1111/dth.12832DOI Listing
January 2019
6 Reads

A case of erythrodermic psoriasis successfully treated with ixekizumab.

Dermatol Ther 2019 Jan 16:e12825. Epub 2019 Jan 16.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Erythrodermic psoriasis (EP) is the most severe form of psoriasis, resulting in significant morbidity and mortality. International guidelines on EP treatment are lacking, with most of the biologic drugs being used basing on case reports or small case series. Ixekizumab, a fully human anti-interleukin (IL)-17A monoclonal antibody, is approved for moderate to severe plaque psoriasis while its use in EP is off label. Read More

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http://dx.doi.org/10.1111/dth.12825DOI Listing
January 2019
1 Read

Relative efficacy of 5-fluorouracil compared with other treatments among patients with actinic keratosis: A network meta-analysis.

Dermatol Ther 2019 Jan 14:e12822. Epub 2019 Jan 14.

Department of Dermatology of Traditional Chinese Medicine, Guangzhou Red Cross Hospital, the Medical College, JiNan University, Guangzhou, China.

Objective: The purpose of this study was to compare the efficacy of 5-fluorouracil (5-FU) with that of other treatments of actinic keratosis (AK).

Methods: A systematic literature review of five databases (including Medline and EMBASE) was first performed to identify randomized controlled trials (RCTs). A network meta-analysis (NMA) based on a random-effects Bayesian model was then performed on the outcomes for patients with total clearance and lesions reduced from baseline. Read More

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http://dx.doi.org/10.1111/dth.12822DOI Listing
January 2019
1 Read

Treatment of lipedema by low-volume micro-cannular liposuction in tumescent anesthesia: Results in 111 patients.

Dermatol Ther 2019 Jan 14:e12820. Epub 2019 Jan 14.

Center of Physical and Rehabilitative Medicine, Städtisches Klinikum Dresden, Dresden, Germany.

Lipedema is a painful disease of subcutaneous adipose tissue leading to bilateral increase of leg and/or arm volume, but sparing hands and feet. Although conservative treatment with complex decongestive therapy has been considered as the fundamental treatment, micro-cannular liposuction in tumescent anesthesia has become a surgical option. We report on 111 patients mostly with advanced lipedema treated by this technique in our center between 2007 and 2018. Read More

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http://doi.wiley.com/10.1111/dth.12820
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http://dx.doi.org/10.1111/dth.12820DOI Listing
January 2019
8 Reads

Mucocutaneous ulcers as forerunners of methotrexate toxicity.

Dermatol Ther 2019 Jan 14:e12823. Epub 2019 Jan 14.

Department of Medical, Surgical and Neuro-Sciences, Dermatology Unit, University of Siena, Siena, Italy.

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http://dx.doi.org/10.1111/dth.12823DOI Listing
January 2019
1 Read

Low dose thalidomide monotherapy for the treatment of recalcitrant erosive lichen planus.

Dermatol Ther 2019 Jan 14:e12824. Epub 2019 Jan 14.

Department of Pathology, Dr RML Hospital & PGIMER, New Delhi, India.

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http://doi.wiley.com/10.1111/dth.12824
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http://dx.doi.org/10.1111/dth.12824DOI Listing
January 2019
2 Reads

Post-erysipela panniculitis ossificans of the lower leg treated with pentoxifylline.

Dermatol Ther 2019 Jan 14:e12821. Epub 2019 Jan 14.

Department of Clinical-Surgical, Diagnostic, and Pediatric Science, Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

We report the case of a female patient who developed a firm, wooden-like, nonpitting edema of the left lower leg after a dermo-hypodermitis. The clinical picture was accompanied by intense pain, strongly impacting the patient's quality of life. A soft-tissue ultrasound demonstrated several millimetric hyperechoic linear lesions whose histopathological examination was conclusive for panniculitis ossificans. Read More

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http://doi.wiley.com/10.1111/dth.12821
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http://dx.doi.org/10.1111/dth.12821DOI Listing
January 2019
8 Reads

Injection site reactions with the use of biological agents.

Dermatol Ther 2019 Jan 13:e12817. Epub 2019 Jan 13.

Department of Dermatology, Hadassah Medical Center, Hebrew University of Jerusalem, The Faculty of Medicine, Jerusalem, Israel.

Injection site reactions (ISRs) are a local phenomenon defined as a constellation of symptoms, including swelling, erythema, pruritus, and pain around the site of injection. This article reviews the different aspects of ISRs, including their epidemiology and pathogenesis, and provides practical guidance to diagnose and treat such reactions. More focus is given to food and drug administration (FDA)-approved biological agents and biosimilars, which are licensed mainly for the treatment of dermatological conditions, including psoriasis, atopic dermatitis, and chronic urticaria. Read More

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http://doi.wiley.com/10.1111/dth.12817
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http://dx.doi.org/10.1111/dth.12817DOI Listing
January 2019
5 Reads

Pentoxyfilline as a treatment for subcorneal pustular dermatosis.

Dermatol Ther 2019 Jan 14:e12818. Epub 2019 Jan 14.

Department of Dermatology, West Virginia University School of Medicine, Morgantown, West Virginia.

Subcorneal pustular dermatosis (SPD) is a rare pustular neutrophilic dermatosis in which groups of sterile pustules appear in the superficial (subcorneal) skin. This chronic condition can be associated with significant morbidity and decreased quality of life. Dapsone is the first-line therapy for SPD, but some patients fail to respond or cannot tolerate it. Read More

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http://doi.wiley.com/10.1111/dth.12818
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http://dx.doi.org/10.1111/dth.12818DOI Listing
January 2019
5 Reads

Use of potassium iodide in deep mycosis.

Dermatol Ther 2019 Jan 14:e12819. Epub 2019 Jan 14.

Department of Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://doi.wiley.com/10.1111/dth.12819
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http://dx.doi.org/10.1111/dth.12819DOI Listing
January 2019
5 Reads
1.478 Impact Factor

Local hyperthermia cleared multifarious viral warts in a patient with Cushing's syndrome.

Dermatol Ther 2019 Jan 11:e12815. Epub 2019 Jan 11.

Department of dermatology, NHC/Ministry of Education/Liaoning Province Key Laboratory of Immunodermatology (China Medical University) The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning, P.R. China.

A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. Read More

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http://dx.doi.org/10.1111/dth.12815DOI Listing
January 2019
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Adherence to Mediterranean diet in Spanish patients with psoriasis: Cardiovascular benefits?

Dermatol Ther 2019 Jan 10:e12810. Epub 2019 Jan 10.

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Several studies have evaluated the role of individual nutrients on psoriasis. Only a few of them have evaluated the benefits of healthy dietary patterns and the effect of the Mediterranean diet on psoriasis with promising results. Moderate-severe psoriasis is associated with chronic systemic inflammation and increased cardiovascular risk. Read More

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http://dx.doi.org/10.1111/dth.12810DOI Listing
January 2019
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Cigarette smoking reduces the efficacy of intralesional vitamin D in the treatment of warts.

Dermatol Ther 2019 Jan 9:e12816. Epub 2019 Jan 9.

Dermatology Department, Al Haud Al Marsud Hospital, Cairo, Egypt.

Cigarette smoking may decrease serum levels of vitamin D and reduce its efficacy. We aimed to evaluate the safety and efficacy of intralesional vitamin D in the treatment of warts and to investigate the effect of smoking on its efficacy in these cases. The study included 20 patients with verruca vulgaris and deep palmoplantar warts. Read More

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http://dx.doi.org/10.1111/dth.12816DOI Listing
January 2019
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