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    77 results match your criteria Dermatologic Manifestations of Renal Disease

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    Therapeutic Apheresis in Hematologic, Autoimmune and Dermatologic Diseases With Immunologic Origin.
    Ther Apher Dial 2016 Oct 16;20(5):433-452. Epub 2016 Sep 16.
    Inselklinik Heringsdorf GmbH, 17424, Seeheilbad Heringsdorf, Germany.
    The process of curing a patient by removing his illness by extracting blood is a very old one. Many years ago, phlebotomy was practiced to cure illness. Now, this old process, placed on a rational basis with therapeutic apheresis (TA), is being followed in clinical practice. Read More

    Renal disease in patients infected with hepatitis B virus.
    Trop Gastroenterol 2015 Oct-Dec;36(4):220-8
    Infection with hepatitis B virus (HBV) can result in hepatic diseases which may include an asymptomatic non-replicative carrier state, immunotolerant phase characterized by high DNA levels without significant hepatic injury, immune-reactive phase characterized by occurrence of chronic hepatitis and fibrosis in the liver, or complications like cirrhosis or hepatocellular carcinoma. Extrahepatic manifestations may also accompany HBV infection. These may include serum sickness syndrome, polyarthralgia, polyarthritis, dermatologic manifestations like pitted keratolysis, urticaria, purpura, oral lichen planus or Gianotti-Crosti syndrome-a childhood papular eruption. Read More

    Skin manifestations associated with kidney cancer.
    Semin Oncol 2016 Jun 23;43(3):408-12. Epub 2016 Feb 23.
    Levine Cancer Institute at Carolinas Medical Center, Charlotte, NC.
    Kidney cancer is a heterogenous disease encompassing several distinct clinicopathologic entities with different underlying molecular aberrations and clinical outcomes. Renal cell carcinoma (RCC) has been shown to evoke immunologic responses that can impact the natural history of disease and clinical presentation. It is important to recognize atypical presentations of disease, including cutaneous manifestations. Read More

    Birt-Hogg-Dubé syndrome: a large single family cohort.
    Respir Res 2016 Feb 29;17:22. Epub 2016 Feb 29.
    Department of Medicine, University of Calgary, Calgary, AB, Canada.
    Background: Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant condition characterized by dermatologic lesions, pulmonary manifestations, and renal tumors. The syndrome arises from germline mutations in the folliculin (FLCN) gene. We present findings from the single largest family BHD cohort described to date. Read More

    Clinical study of 20 patients with incontinentia pigmenti.
    Int J Dermatol 2016 Feb 6;55(2):e87-93. Epub 2015 Nov 6.
    Section of Dermatology, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.
    Background: Incontinentia pigmenti (IP) is a rare genodermatosis with early prenatal lethality in affected males. Clinical manifestations are usually more exuberant in sporadic than in familial cases. Cutaneous manifestations occur in all sporadic cases and about 96% of familial cases. Read More

    Dermatologic Extrahepatic Manifestations of Hepatitis C.
    J Clin Transl Hepatol 2015 Jun 15;3(2):127-33. Epub 2015 Jun 15.
    Department of Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Heath Center, Farmington, CT, USA.
    Hepatitis C virus (HCV) affects millions of people worldwide, and an estimated 3.2 million people in the United States. HCV is a hepatotropic and lymphotropic virus that causes not only liver disease, but also a significant number of extrahepatic manifestations (EHMs). Read More

    Dermatologic Manifestations in End-stage Renal Disease.
    Iran J Kidney Dis 2015 Sep;9(5):339-53
    Division of General Internal Medicine, Toronto General Hospital, University of Toronto, Toronto, Canada.
    End-stage renal disease (ESRD) is a rapidly growing global health problem within the past decades due to increased life expectancy, diabetes mellitus, hypertension, and vascular diseases. Since ESRD is not curable definitively, patients suffering from ESRD have a very low quality of life; therefore, symptomatic management is the cornerstone of medical treatment. Uremia affects almost all body organs, such as skin, through different mechanisms including biochemical, vascular, neurologic, immunologic, hematologic, endocrine, and electrolyte and volume balance disturbances. Read More

    [Skin manifestations in adults with a liver allograft].
    Rev Med Chil 2015 May;143(5):584-8
    Background: Skin manifestations after liver transplantation are increasing due to long term immunosuppressive therapy along with an increase in patient survival. Several studies have reported dermatologic complications following renal transplant, but few have studied dermatologic problems after liver transplantation.

    Aims: To describe the different types of cutaneous lesions encountered in adults receiving a liver allograft. Read More

    Multifocal cutaneous alternariosis in a 70-year-old Kenyan renal transplant patient.
    Dermatol Online J 2014 Jul 15;20(7). Epub 2014 Jul 15.
    University of Massachusetts.
    Alternaria species are a group of dematiaceous fungi that are ubiquitous in nature and are becoming an increasingly important cause of disease in immunocompromised patients. We present a case of a 70 year old renal transplant recipient with multiple areas of cutaneous Alternaria infections likely introduced during local trauma. Treatment has required a combination of systemic therapy and surgical excision. Read More

    [Skin lesions in chronic renal dialysis].
    J Bras Nefrol 2014 Jan-Mar;36(1):42-7
    Faculdade Assis Gurgacz, Cascavel, PR, Brasil.
    Objective: Cutaneous and mucosal disorders are the most common problems in patients on long-term hemodialysis. The dialysis prolongs the life expectancy, giving time of these changes to manifest. The aim of this study was to evaluate the prevalence of dermatologic problems among patients with chronic renal disease (CRD) undergoing hemodialysis. Read More

    Management of common adverse events in patients treated with sorafenib: nurse and pharmacist perspective.
    Semin Oncol 2014 Feb 9;41 Suppl 2:S17-28. Epub 2014 Jan 9.
    Nurse Practitioner, Hospital of the University of Pennsylvania, Department of Otorhinolaryngology, Philadelphia, PA. Electronic address:
    Sorafenib, a tyrosine kinase inhibitor, is indicated for the treatment of patients with unresectable hepatocellular carcinoma (HCC) and advanced renal cell carcinoma (RCC). Sorafenib is currently being evaluated in phase II and III trials in various malignancies as a single agent (locally advanced/metastatic radioactive iodine-refractory differentiated thyroid cancer [DTC]), as part of multimodality care (HCC), and in combination with chemotherapies (metastatic breast cancer). Grade 1 and 2 adverse events (AEs) that commonly occur during treatment (ie, dermatologic manifestations, diarrhea, fatigue, and hypertension) should be proactively managed. Read More

    Germline PTEN mutation Cowden syndrome: an underappreciated form of hereditary kidney cancer.
    J Urol 2013 Dec 11;190(6):1990-8. Epub 2013 Jun 11.
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
    Purpose: Cowden syndrome is a hereditary cancer syndrome associated with a germline mutation in PTEN. Patients are predisposed to multiple malignancies including renal cell carcinoma.

    Materials And Methods: Patients with Cowden syndrome were evaluated as part of a clinical protocol. Read More

    Detection of Ro/SS-A antibodies in lupus erythematosus: what does it mean for the dermatologist?
    J Am Acad Dermatol 2013 Mar 12;68(3):385-94. Epub 2012 Oct 12.
    Department of Dermatology, Innsbruck Medical University, Innsbruck, Austria.
    Background: Lupus erythematosus (LE) is a systemic autoimmune disease. However, some patients have only cutaneous LE (CLE), whereas others develop internal organ involvement. Ro/SS-A antibodies are frequently detected in photosensitive variants of LE. Read More

    A prospective study of cutaneous abnormalities in patients with chronic kidney disease.
    Indian J Nephrol 2012 Mar;22(2):116-20
    Department of Dermatology, Christian Medical College and Hospital, Ludhiana, Punjab, India.
    There are diverse ways in which the skin is affected by chronic kidney disease (CKD). Various specific and nonspecific skin abnormalities are observed in patients with CKD. The aim of the study was to document the prevalence of skin diseases that commonly occur in patients with CKD on medical treatment and dialysis. Read More

    Composite B-cell and T-cell lineage post-transplant lymphoproliferative disorder of the lung with unusual cutaneous manifestations of mycosis fungoides.
    Am J Dermatopathol 2012 Apr;34(2):220-5
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC, USA.
    We present the case of a 17-year-old male kidney transplant recipient who presented initially with dermatologic symptoms and was found to have histologic changes in the skin that were consistent with mycosis fungoides. Shortly after this diagnosis was made, imaging studies demonstrated multifocal interstitial and airspace consolidation in both lungs. Physical examination revealed no lymphadenopathy or hepatosplenomegaly, but an open lung biopsy revealed an Epstein-Barr virus (EBV)-negative monomorphic T-cell posttransplant lymphoproliferative disorder (PTLD) with a concomitant EBV-positive B-cell PTLD involving the same lesion of the lung. Read More

    Chloracne-like drug eruption associated with sorafenib.
    J Drugs Dermatol 2011 Nov;10(11):1331-4
    Department of Dermatology, Texas Tech University Health Sciences Center, 3601 Fourth Street, Lubbock, TX 79430, USA.
    Sorafenib is a chemotherapeutic agent primarily used to treat metastatic renal cell carcinoma. It is a multikinase inhibitor that blocks cell proliferation and angiogenesis. Numerous cutaneous side effects have been reported in association with this medication, including acral erythema, inflammation of actinic keratoses, erythema multiforme, vasculitis, and keratoacanthomas. Read More

    [Early diagnosis of Fabry disease in children].
    Minerva Pediatr 2011 Oct;63(5):425-30
    Dipartimento di Scienze Mediche, Università del Piemonte Orientale, Novara, Italia.
    Fabry disease, a rare X-linked lysosomal storage disorder, is caused by deficiency of the enzyme α-galactosidase A. The incidence, ranging from one over 40 000 to one over 11 7000 worldwide is probably underestimated due to its unspecific pattern of presentation. The symptoms, including neurological, gastrointestinal, renal, ophthalmological and dermatologic manifestations, start in childhood and adolescence, cause a significant morbidity and are likely to affect the patient's quality of life. Read More

    Extraintestinal manifestations of inflammatory bowel disease.
    Gastroenterol Hepatol (N Y) 2011 Apr;7(4):235-41
    Dr. Levine is an Associate Physician in the Division of Gastroenterology, Hepatology, and Endoscopy at Brigham and Women's Hospital and an Instructor of Medicine at Harvard Medical School, both in Boston, Massachusetts.
    Extraintestinal manifestations of inflammatory bowel disease are prevalent in both ulcerative colitis and Crohn's disease. The most common manifestations involve the musculoskeletal and dermatologic systems. Other manifestations involve the hepatopan-creatobiliary system (eg, primary sclerosing cholangitis) as well as the ocular, renal, and pulmonary systems. Read More

    Alefacept therapy for nephrogenic systemic fibrosis: a case series.
    J Drugs Dermatol 2011 Aug;10(8):922-4
    Department of Dermatology, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.
    Nephrogenic systemic fibrosis (NSF) is a recently described systemic fibrosing disorder that develops in the setting of renal insufficiency. Exposure to gadolinium has been implicated in its development. While the primary manifestations are cutaneous, systemic fibrosis can also occur. Read More

    [Skin diseases in hemodialysis and kidney transplant patients].
    J Bras Nefrol 2011 Apr-Jun;33(2):268-75
    Faculdade de Medicina, Universidade Federal Fluminense.
    Recently, the world is facing an escalate in the incidence of chronic kidney disease (CKD). Databases containing information about patients in end stage renal disease (ESRD), especially in the United States, were the sources of initial information about it. Brazil has the third largest population on dialysis in the world, and there are about 680 dialysis centers, spread across all units of the federation in the present, providing treatment to an estimated population of almost 90,000 patients. Read More

    Cutaneous manifestations in end-stage renal disease.
    An Bras Dermatol 2011 Mar-Apr;86(2):319-26
    Dermatology Service of the General Polyclinic of Rio de Janeiro and at the Internal Medicine Service (10th Ward) - School of Medicine and Surgery, Federal University of Rio de Janeiro State (UNIRIO) - Rio de Janeiro (RJ), Brazil.
    The prevalence of chronic kidney disease has increased over the last years. The effects of this disease are complex and may lead to dysfunction of multiple organs, including the skin, with most patients presenting with at least one dermatologic alteration. Sometimes these symptoms can be the first clear sign of kidney disease. Read More

    Noninvasive skin measurements to monitor chronic renal failure pathogenesis.
    Biomed Pharmacother 2011 Jul 14;65(4):280-5. Epub 2011 Apr 14.
    School of Pharmacy, Institute of Drug Research, The Hebrew University of Jerusalem, P.O.B. 12065, 91120 Jerusalem, Israel.
    Background/aims: Cutaneous manifestations are common in hemodialysis (HD) patients with chronic renal failure (CRF). Associated with uremia, pruritus is a frequently observed symptom in CRF patients and increases with deteriorating renal function. Skin hydrophilic biomarkers (SHB) may be altered in CRF compared to healthy controls. Read More

    Pediatric systemic lupus erythematosus in Thammasat University Hospital.
    J Med Assoc Thai 2010 Dec;93 Suppl 7:S283-93
    Department of Pediatrics, Faculty of Medicine, Thammasat University, Patumthani, Thailand.
    Systemic lupus erythematosus (SLE) is a common autoimmune disease in children. Current standard therapies carry high adverse effects. Refractory SLE to conventional therapies is not uncommon. Read More

    Epidemiology of skin diseases in renal transplant recipients in a tertiary hospital.
    Ann Acad Med Singapore 2010 Dec;39(12):904-5
    Department of Medicine, National University Hospital, Singapore.
    Introduction: There is no published epidemiological data on skin diseases in kidney transplant recipients in this tropical country, which has multi-ethnic groups with the Chinese as the predominant ethnic group.

    Materials And Methods: Skin diseases of 143 renal transplant recipients were studied in a skin clinic of a tertiary institution during annual surveillance visits from June 2006 to March 2009.

    Results: Our study showed that except the common drug specific skin manifestations, sebaceous hyperplasia (56. Read More

    Blood pressure, proteinuria and nephropathy in Fabry disease.
    Nephron Clin Pract 2011 11;118(1):c43-8. Epub 2010 Nov 11.
    Department of Internal Medicine, University of Alabama, 1530 3rd Avenue South, Tuscaloosa, AL 34294, USA.
    Background/aims: Fabry disease is an X-linked disorder leading to abnormal accumulation of glycosphingolipids with multisystem involvement, including cardiac, renal, dermatologic and neurologic manifestations. Fabry nephropathy, specifically proteinuria and progressive chronic kidney disease, have taken center stage over the past decade, defining disease outcomes as well as mortality associated with Fabry disease. Systemic blood pressure among patients with Fabry disease is relatively low, compared to other forms of proteinuric chronic kidney disease. Read More

    Hepatitis C virus as a multifaceted disease: a simple and updated approach for extrahepatic manifestations of hepatitis C virus infection.
    Hepat Mon 2010 1;10(4):258-69. Epub 2010 Dec 1.
    Department of Internal Medicine, Minia University, Minia, Egypt.
    Hepatitis C virus infection is an emerging disease and a public health problem in the world. There are accumulating data regarding extra hepatic manifestation of HCV, such as rheumatologic manifestations, endocrine, hematologic, dermatologic, renal, neurologic, and systemic manifestations. The therapy of them needs more attention to some exacerbations of extra hepatic manifestation and in some situation it needs different approaches. Read More

    Erythema induratum of Bazin.
    Dermatol Online J 2010 Apr 15;16(4). Epub 2010 Apr 15.
    University of California Davis, Sacramento, California, USA.
    An 81-year-old woman with a history of renal cell carcinoma and years of slowly, progressively enlarging pulmonary nodules of uncertain etiology presented with several weeks of painful lower extremity nodules. A biopsy revealed changes consistent with nodular vasculitis. A purified protein derivative and QuantiFERON test were positive, favoring the diagnosis of erythema induratum of Bazin. Read More

    Extraintestinal manifestations of inflammatory bowel disease: epidemiology, diagnosis, and management.
    Ann Med 2010 Mar;42(2):97-114
    Department of Gastroenterology, Medical Section, Herlev Hospital, University of Copenhagen, Denmark.
    Abstract Extraintestinal manifestations occur rather frequently in inflammatory bowel disease (IBD), e.g. ulcerative colitis (UC) and Crohn's disease (CD). Read More

    Nephrogenic systemic fibrosis: a pathologic study of autopsy cases.
    Arch Pathol Lab Med 2009 Dec;133(12):1943-8
    Department of Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital and Harvard Medical School, Boston, USA.
    Context: -Nephrogenic systemic fibrosis (NSF) is a rare but serious disorder initially described as a purely dermatologic process. Isolated autopsy reports have described multiorgan involvement by this disease.

    Objective: -To further illustrate the varied and systemic involvement of NSF by describing the autopsy experience at the Massachusetts General Hospital. Read More

    Cutaneous manifestations in renal transplant recipients of Santiago, Chile.
    Transplant Proc 2009 Nov;41(9):3752-4
    Department of Dermatology, Pontificia Universidad Católica de Chile, Chile.
    Introduction: Renal transplant recipients have a heightened risk of developing various cutaneous manifestations, such as skin infections, skin cancer, and secondary effects of immunosuppressive drugs. These manifestations differ depending on the evaluated population. The objective of this study was to describe the prevalence of cutaneous manifestations among renal transplant recipients in Chile between 1979 and 2008. Read More

    Skin manifestations of systemic disease.
    Aust Fam Physician 2009 Jul;38(7):498-505
    St Vincent's Hospital and Monash Medical Centre, Victoria.
    Background: Dermatologic complaints are a common reason for presentation to a general practitioner. In some cases, one needs to determine if the complaint may be a manifestation of a more serious underlying systemic disease.

    Objective: This article aims to highlight common dermatologic presentations where further assessment is needed to exclude an underlying systemic disease, to discuss classic cutaneous features of specific systemic diseases, and to outline rare cutaneous paraneoplastic syndromes. Read More

    Cutaneous and mucosal manifestations in patients on maintenance hemodialysis: a study of 101 patients in Sari, Iran.
    Iran J Kidney Dis 2008 Apr;2(2):86-90
    Department of Dermatology, Mazandaran University of Medical Sciences, Sari, Iran.
    Introduction: Cutaneous and mucosal disorders are of the common problems in patients on long-term hemodialysis. The aim of this study was to evaluate the frequency of dermatologic problems among patients with end-stage renal disease (ESRD) who receive maintenance hemodialysis.

    Materials And Methods: One hundred and one patients with ESRD on hemodialysis were studied. Read More

    A novel missense mutation in the SLC6A19 gene in a Chinese family with Hartnup disorder.
    Int J Dermatol 2009 Apr;48(4):388-92
    Department of Dermatology, Peking University First and Third Hospital, Beijing and He Ping Hospital, Chang Zhi Medical College, Changzhi, China.
    Background: Hartnup disease is a rare autosomal-recessive abnormality of renal and gastrointestinal neutral amino acid transport associated with neurologic, psychiatric, and dermatologic symptoms. Mutations in the SLC6A19 gene have been proposed to be responsible for the underlying changes in this disorder.

    Aim: To investigate a pedigree with Hartnup disorder and to search for the mutation in the SLC6A19 gene in this pedigree. Read More

    Multiple toxic effects of low-dose methotrexate in a patient treated for psoriasis.
    Am J Health Syst Pharm 2008 Nov;65(22):2117-21
    South Carolina College of Pharmacy, University of South Carolina, Columbia 29208, USA.
    Purpose: A case of toxicity encountered with low-dose methotrexate therapy is discussed.

    Summary: A 59-year-old African American woman receiving long-term therapy for psoriasis came to the hospital with painful ulcers, difficulty swallowing, cutaneous lesions, and acute renal failure. Her medical history included type 2 diabetes mellitus, hypertension, coronary artery disease, morbid obesity, and psoriasis. Read More

    Canine leishmaniosis.
    Pol J Vet Sci 2008 ;11(2):151-8
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Live Sciences (SGGW), Warsaw, Poland.
    Canine visceral leishmaniosis (CVL) is an infectious disease of zoonotic potential, caused by protozoan parasite of the genus Leishmania. Common clinical manifestations of canine visceral leishmaniosis include decrease of appetite, progressive weight loss, exercise intolerance, peripheral lymph node and spleen enlargement, chronic renal and liver disease, muscle, atrophy, polyarthritis and others. Because the Polish literature in the field contains no information on leishmaniosis in animals the recognised case of this disease is presented. Read More

    Kidney disease in nail-patella syndrome.
    Pediatr Nephrol 2009 Dec 6;24(12):2345-54. Epub 2008 Jun 6.
    Division of Nephrology, MS#40, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
    Nail-patella syndrome (NPS) is a pleiotropic autosomal-dominant disorder due to mutations in the gene LMX1B. It has traditionally been characterized by a tetrad of dermatologic and musculoskeletal abnormalities. However, one of the most serious manifestations of NPS is kidney disease, which may be present in up to 40% of affected individuals. Read More

    Pustular psoriasis after renal transplantation.
    Transplant Proc 2007 May;39(4):1130-1
    Department of Internal Medicine, Charles Nicolle Hospital, Tunis, Tunisia.
    Cutaneous manifestations in renal transplant recipients are frequently represented by infections and cancerous lesions. However, dermatologic lesions secondary to autoimmune diseases are rare. We report a case of pustular psoriasis occurring after renal transplantation in a 31-year-old woman with a history of vitiligo. Read More

    Symptomatic and virological response to antiviral therapy in hepatitis C associated with extrahepatic complications of cryoglobulimia.
    Dig Dis Sci 2007 Sep 6;52(9):2410-7. Epub 2007 Apr 6.
    Department of Medicine, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, USA.
    Mixed cryoglobulins are detected in 50% of patients with hepatitis C; fortunately, few have vasculitis affecting skin, peripheral nerves, kidneys, and synovia. This study was designed to identify the natural history of symptomatic cryoglobulinemia and evaluate the response to antiviral therapy. Patients with hepatitis C complicated by symptomatic cryoglobulinemia were assessed for their disease manifestations and response to antiviral therapy. Read More

    Dermatologic correlates of selected metabolic events.
    J Med 1999 ;30(3-4):149-56
    Dermatology, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103-2714, USA.
    Various metabolic events may lead to dermatologic pathology. Three illustrative examples are glucagonoma syndrome, uremic pruritus, and zinc deficiency. The glucagonoma syndrome, resulting from a glucagon secreting-tumor, is characterized by a distinctive dermatitis, necrolytic migratory erythema. Read More

    Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations.
    Arch Dermatol 2006 Dec;142(12):1591-7
    Department of Dermatology, University of California, San Francisco, USA.
    Objective: To characterize the multisystem chronic inflammatory phenotype, dermatopathologic features, and response to therapy with interleukin 1 receptor antagonist (anakinra) in patients with mutations in the CIAS-1/NALP3 gene.

    Design: Retrospective review of medical records and evaluation of histologic findings.

    Setting: The National Amyloidosis Centre, London, and a tertiary referral clinic for urticaria. Read More

    Cutaneous manifestations in patients with chronic renal failure on hemodialysis.
    Indian J Dermatol Venereol Leprol 2006 Mar-Apr;72(2):119-25
    Department of Dermatology, PSG Hospitals, Peelamedu, Coimbatore, India.
    Background: Chronic renal failure (CRF) presents with an array of cutaneous manifestations. Newer changes are being described since the advent of hemodialysis, which prolongs the life expectancy, giving time for these changes to manifest.

    Aim: The aim of this study was to evaluate the prevalence of dermatologic problems among patients with chronic renal failure (CRF) undergoing hemodialysis. Read More

    Skin diseases in Turkish renal transplant recipients.
    Int J Dermatol 2005 Nov;44(11):939-41
    Department of Dermatology, Ege University School of Medicine, Izmir, Turkey.
    Background: Organ transplant recipients are predisposed to a variety of cutaneous complications due to immunosuppressive therapy. We aimed to determine the prevalence and the clinical spectrum of skin diseases in renal transplant recipients (RTRs).

    Methods: One hundred and eleven RTRs were examined at the Renal Transplantation Center in Ege University Hospital between October 1999 and October 2001. Read More

    Cutaneous manifestations in Italian kidney transplant recipients.
    Transplant Proc 2005 Jul-Aug;37(6):2527-8
    Department of Dermatology, University of L'Aquila, L'Aquila, Italy.
    Several cutaneous disorders may occur in organ transplant recipients. We examined the incidence and the clinical spectrum of cutaneous manifestations among kidney transplant recipients. One hundred nine patients (70 males and 39 females), aged 19 to 69 years (mean: 42. Read More

    Mercury exposure: evaluation and intervention the inappropriate use of chelating agents in the diagnosis and treatment of putative mercury poisoning.
    Neurotoxicology 2005 Aug;26(4):691-9
    Agency for Toxic Substances and Disease Registry, Division of Toxicology (F-32), 1600 Clifton Road, Atlanta, GA 30333, USA.
    Public awareness of the potential for mercury to cause health problems has increased dramatically in the last 15 years. It is now widely recognized that significant exposure to all forms of mercury (elemental/metallic and both inorganic and organic compounds) can result in a variety of adverse health effects, including neurological, renal, respiratory, immune, dermatologic, reproductive, and developmental sequellae. And while the various media have made the general population cognizant of the need to avoid unnecessary exposure to this naturally occurring element, there has also evolved a growing tendency to attribute unexplainable neurologic, as well as other, signs and symptoms to mercury, whether or not significant exposure to mercury has actually occurred. Read More

    Fabry disease. A case report.
    Acta Dermatovenerol Alp Pannonica Adriat 2005 Mar;14(1):15-9
    Dermatology Service, General Hospital Slovenj Gradec, 2380 Slovenj Gradec, Slovenija.
    Fabry disease is an under-recognized X-linked recessive lysosomal storage disorder resulting from the deficient activity of the enzyme alpha-galactosidase A (alpha-Gal A). The first case of Fabry disease in Slovenia was diagnosed in 1991. This 46 year-old male was referred for dermatologic evaluation of a purpura on his abdomen. Read More

    The hand in metastatic disease and acral manifestations of paraneoplastic syndromes.
    Hand Clin 2004 Aug;20(3):335-43, vii
    Division of Hand, Elbow, and Microsurgery, Department of Orthopaedic Surgery, University of Michigan Medical Center, 2098 South Main Street, Ann Arbor, MI 48103, USA.
    Metastatic tumors to the hand and wrist are rare, accounting for approximately 0.1% of all metastatic lesions to the skeleton. The biochemically mediated pathways of bone metastases, the location of the hand at the distal extremity, and the small amount of marrow in the bones of the hand and wrist account for the low prevalence of acrometastases. Read More

    Cutaneous metastases from genitourinary malignancies.
    Urology 2004 Jun;63(6):1021-6
    Department of Urological Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
    Objectives: To review the world literature for reports of cutaneous metastases from primary genitourinary malignancies and compare them with our experience during a 10-year period. Cutaneous metastases from primary visceral malignancies are uncommon manifestations of advanced disease. Among patients with urologic malignancies, the incidence and appearance of cutaneous metastases are not well established and recognition is poor among practicing urologists. Read More

    Severe systemic reaction to (99m)Tc-methylene diphosphonate: a case report.
    J Nucl Med Technol 2003 Jun;31(2):76-8
    Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, United Kingdom.
    We report an unusual severe systemic reaction that occurred in a woman after a (99m)Tc-methylene diphosphonate bone scan and for which no alternative explanation could be found. The bone scintigram showed diffusely increased uptake in the liver and kidneys accompanied by reversible dysfunction of these organs and dermatologic manifestations. We speculate that an immune-mediated mechanism may have caused this unusual reaction. Read More

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