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    1805 results match your criteria Dermatofibrosarcoma Protuberans

    1 OF 37

    Dermoscopy of uncommon variants of dermatofibrosarcoma protuberans.
    J Eur Acad Dermatol Venereol 2017 Feb 13. Epub 2017 Feb 13.
    Department of Dermatology, University of Naples Federico II, Italy.
    Darier-Ferrand dermatofibrosarcoma protuberans (DFSP) is a locally aggressive fibrohistiocytic tumour with a low metastatic potential.(1) Because of its rarity, slow progression and lack of early clinical clues, the diagnosis of DFSP is often delayed. Classical DFSP clinically appeared like an indurated, irregularly-shaped plaques exhibiting flesh to reddish-brown colour. Read More

    Application of COL1A1-PDGFB fusion gene detection by fluorescence in situ hybridization in biopsy tissue of dermatofibrosarcoma protuberans.
    J Dermatol 2017 Feb 2. Epub 2017 Feb 2.
    Department of Pathology, West China Hospital, Sichuan University, Chengdu, China.
    Several uncommon variants of dermatofibrosarcoma protuberans (DFSP) and the limitations of small biopsies render pathological diagnosis difficult. The aim of this study was to analyze the utility of fluorescence in situ hybridization (FISH) in the detection of the collagen type I-α1/platelet derived growth factor-β (COL1A1-PDGFB) fusion gene in biopsies of DFSP. Twenty-three consecutive biopsy specimens of DFSP were reviewed for clinicopathological features and examined with the COL1A1-PDGFB fusion probe and PDGFB break-apart probe using FISH analysis. Read More

    Association of patient demographic characteristics with Dermatofibrosarcoma Protuberans tumor size at diagnosis in the National Cancer Data Base.
    Br J Dermatol 2017 Feb 1. Epub 2017 Feb 1.
    Department of Dermatology, University of Arizona College of Medicine, Phoenix, AZ.
    Dermatofibrosarcoma protuberans (DFSP) is a rare, infiltrative but low-grade cutaneous tumor. Middle-aged and younger adults, males, and African-Americans are more likely to be affected by this malignancy, with up to 5 cases per million reported annually in the US. Despite its low metastatic potential and excellent survival, DFSP is prone to recurrence and can be very locally destructive. Read More

    Sclerosing Dermatofibrosarcoma Protuberans Shows Significant Overlap With Sclerotic Fibroma in Both Routine and Immunohistochemical Analysis: A Potential Diagnostic Pitfall.
    Am J Dermatopathol 2017 Feb;39(2):83-88
    Departments of *Dermatology, and †Pathology, University of California San Francisco, San Francisco, CA.
    Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low-to-intermediate grade sarcoma with several histologic variants, including pigmented (Bednar tumor), sclerosing, myxoid, atrophic, and DFSP with fibrosarcomatous changes. Two patterns of sclerosis in DFSP can be observed, a sclerotic fibroma-like pattern and a morphea/lichen sclerosus-like pattern. Partial biopsies of sclerosing DFSPs with the sclerotic fibroma pattern can be misdiagnosed as sclerotic fibroma or other benign sclerosing tumors (eg, perineurioma, dermatofibroma). Read More

    Imatinib in Dermatofibrosarcoma: Targeted Therapy or Immunotherapy?
    J Invest Dermatol 2017 Feb;137(2):277-279
    Department of Dermatology, University of Duisburg-Essen, Essen, Germany; Translational Skin Cancer Research, German Cancer Consortium, West German Cancer Center, Essen, Germany. Electronic address:
    There is increasing evidence that certain kinase inhibitors are able to foster two strategies, i.e. inhibition of oncogenic activated molecular pathways and modulation of immunological processes. Read More

    Unusual Signal Patterns of Break-apart FISH Probes Used in the Diagnosis of Soft Tissue Sarcomas.
    Pathol Oncol Res 2017 Jan 20. Epub 2017 Jan 20.
    1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
    Break-apart FISH probes are the most popular and reliable type of FISH probes used to confirm certain pathological diagnoses. The interpretation is usually easy, however, in some instances it is not so unequivocal. Our aim was to reveal and elucidate the problems occurring in the process of evaluation of the break-apart probe results. Read More

    A single-institutional review of 68 patients with dermatofibrosarcoma protuberans: wide re-excision after inadequate previous surgery results in a high rate of local control.
    World J Surg Oncol 2017 Jan 5;15(1). Epub 2017 Jan 5.
    Department of Plastic Surgery, Burn Centre, Hand Centre, BG-University Hospital Bergmannsheil, Buerkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.
    Background: Dermatofibrosarcoma protuberans (DFSP) is a cutaneous soft tissue sarcoma characterized by an indolent but aggressive local growth. Unplanned excisions with positive margins are common, and the prognostic impact of radical re-excisions is still unclear. The aim of the present study was to identify prognostic indicators of recurrence-free survival (RFS) in patients with DFSP through a long-term follow-up. Read More

    Superficial Acral Fibromyxoma: Report of 13 Cases With New Immunohistochemical Findings.
    Am J Dermatopathol 2017 Jan;39(1):14-22
    *Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain; †Department of Pathology, Hospital 12 de Octubre, Universidad Complutense, Madrid, Spain; and ‡Dermatopathology Laboratory, Friedrichschafen, Germany.
    Background: Superficial acral fibromyxoma (SAF) is a benign, soft tissue neoplasm preferably located on the digits.

    Methods: We collected 13 cases of SAF and evaluated their clinical, histopathologic, and immunohistochemical features.

    Results: This study included 9 males and 4 females, median age 54 years. Read More

    Incidence and Clinical Features of Rare Cutaneous Malignancies in Olmsted County, Minnesota, 2000 to 2010.
    Dermatol Surg 2017 Jan;43(1):116-124
    *Department of Dermatology, Mayo Clinic, Rochester, Minnesota;†Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Minnesota;‡Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota.
    Background: The incidence of rare cutaneous malignancies is unknown. Current estimates of rare cutaneous malignancy incidences are based on broad epidemiologic data or single institution experiences, not population-based data.

    Objective: To determine the incidence of several rare nonmelanoma skin cancers. Read More

    Nodular Fasciitis Complicating a Staged Surgical Excision of Dermatofibrosarcoma Protuberans.
    Case Rep Dermatol Med 2016 27;2016:6074182. Epub 2016 Nov 27.
    Department of Dermatology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
    Dermatofibrosarcoma protuberans (DFSP) is an unusual spindle cell tumor with a high rate of local recurrence with traditional excision. Fortunately, Mohs micrographic surgery yields excellent cure rates for this neoplasm due to contiguous tumor spread and meticulous tumor mapping and margin analysis. We present the unique case of a patient treated with a modified Mohs technique with an analysis of the final margin with permanent sections, who developed a spindle cell neoplasm in the margins of her second stage excision consistent with nodular fasciitis. Read More

    Dermatofibroma of the Eyelid with Monster Cells.
    Surv Ophthalmol 2016 Dec 21. Epub 2016 Dec 21.
    Harvard Medical School; The Department of Dermatology, Massachusetts General Hospital.
    Dermatofibromas are most frequently encountered in women on the lower extremities, often after minor trauma. A 64-year-old woman developed a recurrent lesion of the right lower eyelid. It harbored "monster cells" that were large, with either multiple nuclei or a single, large, convoluted and hyperchromatic nucleus. Read More

    Dermatofibrosarcoma Protuberans-Like Tumor With COL1A1 Copy Number Gain in the Absence of t(17;22).
    Am J Dermatopathol 2016 Dec 14. Epub 2016 Dec 14.
    *Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY; †Department of Medicine, Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY; and ‡Department of Medicine, Memorial Sloan Kettering Cancer Center and Department of Medicine, Weill Cornell Medical College, New York, NY.
    A 57-year-old woman presented with a 3-year history of a progressive firm plaque on the right cheek. Skin biopsies revealed a bland, storiform, spindle-cell proliferation involving the deep dermis and subcutaneous fat. By immunohistochemistry, the tumor cells were diffusely positive for CD34 and caldesmon with multifocal reactivity for epithelial membrane antigen and focal, weak staining for smooth muscle actin. Read More

    [What surgery for recurrent Darier-Ferrand sarcoma of the chest wall?]
    Rev Pneumol Clin 2016 Dec 12. Epub 2016 Dec 12.
    Service de chirurgie thoracique C1, CHU Hassan II, Fès, Maroc; Faculté de médecine et de pharmacie, université Sidi-Mohamed-Ben-Abdellah, Fès, Maroc.
    Introduction: Dermatofibrosarcoma protuberans (Darrier-Ferrand sarcoma, DFSP) is an uncommon tumor. This sarcoma has a tendency to local recurrence, requiring a wide surgical resection.

    Observation: We report herein two cases of patients presenting with recurrent dermatofibrosarcoma protuberans after several surgical resections. Read More

    Mohs micrographic surgery of rare cutaneous tumours.
    J Eur Acad Dermatol Venereol 2016 Dec 15. Epub 2016 Dec 15.
    Department of Dermatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.
    Background: Recurrence rates after Mohs micrographic surgery (MMS) for rare cutaneous tumours are poorly defined.

    Objective: To investigate the recurrence rate after MMS for rare cutaneous tumours at a university centre.

    Methods & Materials: Retrospective review of all rare cutaneous tumours treated with MMS at a large university centre between January 2008 and December 2012. Read More

    Incidence and Outcomes of Dermatofibrosarcoma Protuberans in the US Pediatric Population.
    J Craniofac Surg 2017 Jan;28(1):182-184
    *DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL †New York Medical College, New York, NY ‡Division of Plastic, Aesthetic, and Reconstructive Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL.
    Background: Dermatofibrosarcoma protuberans (DFSP) is a low-grade soft tissue sarcoma. In the pediatric population, DFSP is exceedingly rare. Aim of this study was to describe the epidemiology and clinical outcomes in a large pediatric cohort. Read More

    Dermatofibrosarcoma protuberans: a case report and review of the literature.
    Hippokratia 2016 Jan-Mar;20(1):80-83
    1st Propedeutic Surgical Department, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
    Background: Dermatofibrosarcoma protuberans (DFSP) represents less than 0.1% of all tumors, but it is considered the most common skin sarcoma. Wide local excision (=5 cm) has been largely replaced by Mohs micrographic surgery; however, recurrence is not rare. Read More

    Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum.
    Am J Surg Pathol 2017 Feb;41(2):234-244
    *Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA †Department and Graduate Institute of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
    The classification of atypical adipocytic neoplasms with spindle cell features remains challenging. To better define this category of low-grade lipomatous neoplasms, we present herein the clinical, histologic, and immunohistochemical characteristics of a large series of 232 atypical spindle cell lipomatous tumors. The lesions affected 140 males and 92 females, at an average age of 54 years (range, 6 to 87 y), clinically presenting as a persistent or enlarging mass with a median size of 5 cm. Read More

    Dermatofibrosarcoma protuberans: pathology, genetics, and potential therapeutic strategies.
    Ann Diagn Pathol 2016 Dec 27;25:64-71. Epub 2016 Sep 27.
    Sarcoma Unit, Royal Marsden Hospital, London, United Kingdom.
    Dermatofibrosarcoma protuberans (DFSP), the most common dermal sarcoma, is a malignant fibroblastic tumor most frequently arising in middle-aged adults. It is typically a low-grade sarcoma that grows slowly but has a high rate of local recurrence with low metastatic potential. Dermatofibrosarcoma protuberans is characterized by a specific translocation t(17;22)(q22;q13) leading to the formation of COL1A1-PDGFB fusion transcripts. Read More

    A Tete - a - tete of benign, borderline and malignant fibrohistiocytic tumor.
    Iran J Pathol 2016 ;11(3):286-290
    Dept. of Surgery, Sri Siddhartha Medical College, Tumkur, Karnataka - 572104, India.
    Dermatofibrosarcoma protruberans is a relatively uncommon slow growing, locally aggressive fibrous tumor of the skin. It has a prospensity of progressing to fibrosarcomatous change in 5% of the cases. We present a case of a 56 yr old male with presented to the outpatient department of surgery, Sri Siddhartha Medical College, Tumkur with a chest swelling in 2013. Read More

    Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.
    J Invest Dermatol 2017 Feb 5;137(2):484-493. Epub 2016 Sep 5.
    Unit of Immunotherapy of Human Tumors, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:
    Dermatofibrosarcoma protuberans (DFSP), although rare, is the most frequent skin sarcoma. Here, we focus on DFSP carrying the fibrosarcomatous transformation (FS-DFSP). FS-DFSP responds to imatinib (IM); however, tumor relapse often occurs. Read More

    Dermatofibrosarcoma Protuberans: A comprehensive review on the spectrum of clinico-radiological presentations.
    J Med Imaging Radiat Oncol 2017 Feb 18;61(1):9-17. Epub 2016 Oct 18.
    Department of Radiology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
    Dermatofibrosarcoma Protuberans (DFSP) is a rare malignant soft-tissue neoplasm which is often misdiagnosed due to its indolent clinical course and non-specific radiological appearances. An observation case series was conducted with retrospective review of clinical and radiological data of DFSP patients presenting to a major tertiary hospital in Hong Kong for radiological assessment between November 2006 and February 2016. Seven patients with confirmed histological diagnosis of DFSP were included. Read More

    A Comparison of Mohs Micrographic Surgery and Wide Local Excision for Treatment of Dermatofibrosarcoma Protuberans With Long-Term Follow-up: The Mayo Clinic Experience.
    Dermatol Surg 2017 Jan;43(1):98-106
    *Department of Dermatology, Mayo Clinic, Rochester, Minnesota; †Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota.
    Background: Dermatofibrosarcoma protuberans (DFSP) is a soft tissue tumor with slow infiltrative growth and local recurrence if inadequately excised.

    Objective: To compare long-term outcomes after Mohs micrographic surgery (MMS) and wide local excision (WLE).

    Materials And Methods: Records of patients with DFSP surgically treated with WLE or MMS from January 1955 through March 2012 were retrospectively reviewed. Read More

    Pedunculated Nodules as a Variant of Dermatofibrosarcoma Protuberans.
    Ann Dermatol 2016 Oct 30;28(5):629-631. Epub 2016 Sep 30.
    Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
    Dermatofibrosarcoma protuberans (DFSP) is a rare disease of dermal fibroblastic origin that accounts for less than 5% of all soft tissue sarcomas in adults. DFSP grows slowly and is an asymptomatic lesion at the initial diagnosis. Herein, we report a case of multiple pedunculated nodules as a variant of DFSP. Read More

    Imaging Features of Breast Dermatofibrosarcoma Protuberans in Various Modalities Including FDG-PET CT.
    Iran J Radiol 2016 Apr 23;13(2):e33916. Epub 2016 Feb 23.
    Department of Radiology, Inje University College of Medicine, Ilsan Paik Hospital, Goyang-si, Republic of Korea.
    Dermatofibrosarcoma protuberans is an uncommon malignant mesenchymal tumor of the dermis, which most commonly appears on the body and extremities. A preoperative diagnosis of dermatofibrosarcoma protuberans is extremely difficult, because it is a very rare entity and its appearance is often similar to that of benign breast lesion. Here, we presented a case of breast dermatofibrosarcoma protuberans with associated radiological mammography, ultrasound, magnetic resonance imaging and fludeoxyglucose-positron emission tomography computerized tomography (FDG-PET CT) features. Read More

    Paraffin-embedded micrographic surgery for the treatment of dermatofibrosarcoma protuberans: Analysis of 33 patients.
    Indian J Dermatol Venereol Leprol 2016 Sep 19. Epub 2016 Sep 19.
    Department of Pathology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
    Background: Dermatofibrosarcoma protuberans is a rare malignant tumor with a high rate of recurrence after surgery. Moh's micrographic surgery allows examination of all surgical margins to ensure complete removal.

    Objective: To evaluate the use of Moh's micrographic surgery using paraffin-embedded sections for the treatment of dermatofibrosarcoma protuberans. Read More

    LHRH receptor expression in sarcomas of bone and soft tissue.
    Horm Mol Biol Clin Investig 2016 Nov;28(2):105-111
    Aim: Luteinizing hormone releasing hormone (LHRH) is a neurohormone, secreted by the hypothalamus, which regulates the secretion of gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary. LHRH acts by binding to receptors located in the pituitary gland. These receptors (LHRH receptors) have also been found in the cytoplasm of many tumor cells that involve both the reproductive and non-reproductive organs. Read More

    Trends in incidence and survival analysis in non-melanoma skin cancer from 1994 to 2012 in Girona, Spain: A population-based study.
    Cancer Epidemiol 2016 Dec 14;45:6-10. Epub 2016 Sep 14.
    Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
    Introduction: We present an epidemiological study focused on Non-melanoma skin cancers (NMSC), including squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Merkel cell carcinoma (MCC), dermatofibrosarcoma protuberans (DFS) and adnexal and skin appendages neoplasm (ASAN), a neoplasm understudied in cancer registries.

    Material And Methods: We analyze trends of incidence and survival of NMSC registered with the Cancer Registry of Girona, Spain.

    Results: We found 14389 cases of NMSC, accounting 3,474 SCC, 10729 BCC, 33 MCC, 61 DFSP and 71 ASAN. Read More

    Scalp Tissue Expansion Above a Custom-Made Hydroxyapatite Cranial Implant to Correct Sequelar Alopecia on a Transposition Flap.
    World Neurosurg 2016 Nov 5;95:616.e1-616.e5. Epub 2016 Sep 5.
    Department of Plastic, Reconstructive and Aesthetic Surgery, Hospital Sud, University of Rennes 1, Rennes, France; INSERM U917, University of Rennes 1, Rennes, France; SITI Laboratory, Etablissement Français du Sang Bretagne, Rennes University Hospital, Rennes, France.
    Background: Resection of cranial tumors involving both bone and scalp tissue may require the recruitment of soft tissue using a flap above the bone reconstruction. When a transposition flap has been chosen, the alopecia zone on the donor site may be difficult to treat afterward. Scalp expansion is the gold standard in these situations, but this has never been described above cranial implants. Read More

    Lateral Genicular Artery Flap for Reconstruction of a Large Knee Defect, Following Oncological Resection - Case Report.
    Chirurgia (Bucur) 2016 Jul-Aug;111(4):353-7
    This article presents the case of a 53 years old patient, with ulcerated and infected dermatofibrosarcoma, extended on the anterolateral side of the left knee. The postexcisional defect, exposing patella, was covered through a regional cutaneous flap of the distal third of the thigh, upper lateral genicular artery-based, measuring 20/10 cm, together with expanded free skin split grafts, applied in proximal third of the leg and distal third of the left thigh. Surgical stages and favorable postoperative evolution are exposed. Read More

    Dermatofibrosarcoma Protuberans: Wide Local Excision Versus Mohs Micrographic Surgery.
    Surg Oncol Clin N Am 2016 Oct 3;25(4):827-39. Epub 2016 Aug 3.
    Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Yawkey 7B, Boston, MA 02114, USA. Electronic address:
    Dermatofibrosarcoma protuberans (DFSP) is a rare dermal soft tissue sarcoma characterized by a typically indolent clinical course. The greatest clinical challenge in management of DFSP is achieving local control. There is vigorous debate in the literature as to the optimal surgical approach to these tumors. Read More

    Effectiveness of Imatinib Mesylate Treatment in a Patient with Dermatofibrosarcoma Protuberans with Pulmonary and Pancreatic Metastases.
    Intern Med 2016 1;55(17):2507-11. Epub 2016 Sep 1.
    Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Japan.
    We herein encountered a case of abdominal wall dermatofibrosarcoma protuberans (DFSP) that developed pulmonary and pancreatic metastases 5 years after complete resection. Because specific rearrangements of the platelet-derived growth factor beta (PDGFB) locus by a novel fluorescence in situ hybridization method was detected, the patient was treated with imatinib mesylate at 400 mg/day. A partial response was achieved by imatinib without any specific toxicity. Read More

    Extended V-Y Advancement Flap Reconstruction of a Large Posterior Upper Midline Trunk Defect.
    Plast Reconstr Surg Glob Open 2016 May 20;4(5):e713. Epub 2016 May 20.
    Division of Plastic Surgery, Brigham and Women's Hospital, Boston, Mass.
    Large posterior upper trunk defects can be challenging to reconstruct. Trapezius or latissimus dorsi myocutaneous flaps are principally utilized for reconstruction; however, some defects may not be amenable to this standard approach. Here, we describe a patient with a full-thickness skin and subcutaneous tissue loss of the upper back and inferior cervical region after dermatofibrosarcoma protuberans resection. Read More

    Improving precision of resection by pre-surgery inspections with contrast-enhanced ultrasound for dermatofibrosarcoma protuberans.
    Dermatol Ther 2016 Nov 29;29(6):473-475. Epub 2016 Aug 29.
    Department of Ultrasonography, Peking University Third Hospital, Beijing, China.
    Dermatofibrosarcoma protuberans (DFSP) is a relatively uncommon malignant soft tissue tumor. Although metastasis is rare, it has significant topo-aggressive characteristics with a high recurrence rate. The common treatment of DFSP is surgical resection. Read More

    Dermatofibrosarcoma Protuberans.
    Surg Clin North Am 2016 Oct;96(5):1031-46
    Department of Surgery, Roger Williams Medical Center, 825 Chalkstone Avenue, Prior 4, Providence, RI 02908, USA; Department of Surgery, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA. Electronic address:
    Dermatofibrosarcoma protuberans (DFSP) is a rare superficial soft tissue sarcoma. Its rarity precludes large prospective studies. Clinical diagnosis requires an high index of suspicion. Read More

    Hormone receptor expression in patients with dermatofibrosarcoma protuberans.
    J Am Acad Dermatol 2016 Dec 16;75(6):1205-1209. Epub 2016 Aug 16.
    Department of Dermatology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio.
    Background: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma for which the exact etiology is unknown. Case reports exist of DFSP appearing and growing rapidly during pregnancy, suggesting a hormonal role.

    Objective: Our goal was to determine the expression of estrogen receptors (ERs) and progesterone receptors (PRs) in patients with DFSP. Read More

    Bednar Tumor: An Uncommon Entity.
    Dermatopathology (Basel) 2016 Apr-Jun;3(2):36-8. Epub 2016 Apr 20.
    Department of Pathology, T.N. Medical College and B.Y.L. Nair Hospital, Mumbai, India.
    Bednar tumor is an uncommon variant of dermatofibrosarcoma protuberans. Also known as pigmented dermatofibrosarcoma protuberans, this tumor is of intermediate grade. It is seen in adults and has a predisposition to affect the shoulder region. Read More

    Dermatofibrosarcoma protuberans post basal cell carcinoma excision: A case report.
    Int J Surg Case Rep 2016 29;26:146-9. Epub 2016 Jul 29.
    Texas Tech University Health Sciences Center, School of Medicine, Department of Surgery, 1400S, Coulter Street, Amarillo TX 79106, USA. Electronic address:
    Introduction: Dermatofibrosarcoma protuberans (DFSP) is a rare, malignant, soft tissue neoplasm of the dermis. Tumor recurrence is common following resection, and can be locally devastating if not identified in a timely manner. We report a unique case of this rare tumor. Read More

    A Challenging Giant Dermatofibrosarcoma Protuberans on the Face.
    Case Rep Dermatol Med 2016 30;2016:5926307. Epub 2016 Jun 30.
    Dermatology Department, HIGA Eva Perón, 1650 Buenos Aires, Argentina.
    Dermatofibrosarcoma protuberans (DFSP) is a malignant fibrohistiocytic tumor that appears exclusively on the skin. It is a low-grade malignant soft tissue tumor of subcutaneous tissues that has a propensity for local recurrence but seldom metastasizes. It may rarely occur on the head and neck accounting for less than one percent of total head and neck malignancies. Read More

    Chemotherapy for soft tissue sarcoma.
    Cancer 2016 Oct 19;122(19):2952-60. Epub 2016 Jul 19.
    Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
    Soft tissue sarcoma is a term used to describe a heterogeneous group of many rare tumors. Since the initial description of activity of doxorubicin, several additional agents have been brought to bear in the treatment of these diseases. Despite 2 recent drug approvals, doxorubicin and ifosfamide remain the most effective chemotherapy drugs available for the treatment of majority of these tumors. Read More

    Leiomyomatosis peritonealis disseminata: case report and review of the literature.
    Acta Chir Belg 2016 May 26:1-4. Epub 2016 May 26.
    a Department of Digestive Surgery , Institut Jules Bordet , Brussels , Belgium ;
    Leiomyomatosis peritonealis disseminata (LPD) is typically a benign and rare disorder found in female patients, prior to menopause. It can be found in the subperitoneal or peritoneal spaces and is represented by multiple different sized myomatous nodules (smooth muscle tumors). Additionally, it has also been found in women after menopause as well as in men. Read More

    Dermatofibrosarcoma protuberans of the scalp, with fibrosarcomatous areas masquerading as epidermal inclusion cyst.
    BMJ Case Rep 2016 Jul 7;2016. Epub 2016 Jul 7.
    Lok Nayak Hospital, New Delhi, India.
    Lesions on the scalp are frequently encountered in clinical practice. Commonly diagnosed lesions include epidermal inclusion cysts (EICs), dermoid cysts and lipomas. Dermatofibrosarcoma protuberans (DFSP) is a low-grade malignant skin tumour occurring mostly in the extremities. Read More

    Usefulness of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in dermatofibrosarcoma protuberans on treatment with imatinib.
    Indian J Nucl Med 2016 Jul-Sep;31(3):191-3
    Department of Pathology, Indus Hospital, Visakhapatnam, Andhra Pradesh, India.
    Dermatofibrosarcoma protuberans (DFSP) is a rare locally aggressive tumor with distant metastases being unusual. We present a case of metastatic DFSP treated with imatinib showing complete metabolic response to treatment. Read More

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