6,747 results match your criteria Dermatofibroma


Cutaneous Inflammatory Myofibroblastic Tumor with CARS-ALK Fusion: Case Report and Literature Review.

J Cutan Pathol 2022 May 13. Epub 2022 May 13.

Department of Pathology, Duke University Hospital.

Cutaneous inflammatory myofibroblastic tumors (IMT) constitute a rare entity, generating a diagnostic pitfall when diagnosing spindle cell proliferation within the dermis. Raising awareness of this tumor among dermatopathologists remains vital in differentiating it from common cutaneous tumors such as fibrous histiocytoma, atypical fibroxanthoma, melanoma, poorly differentiated carcinoma, and other more aggressive tumors. Accurate diagnosis of IMT aid in ensuring appropriate management and follow-up for patients while preventing unnecessary harm and overtreatment. Read More

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ETS-related Gene (ERG) is Differentially Expressed in Dermatofibroma (Fibrous Histiocytoma) as Compared With Dermatofibrosarcoma Protuberans and Hypertrophic Scars: A Pilot Immunohistochemical Study.

Appl Immunohistochem Mol Morphol 2022 May 3. Epub 2022 May 3.

Departments of Dermatology.

Immunohistochemical staining can be of great utility in differentiating various cutaneous spindle cell neoplasms, particularly when the histomorphologic appearance of the lesions is inconclusive. Nuclear staining for ETS-related gene (ERG), a highly sensitive endothelial cell marker, has seldom been studied in the context of cutaneous spindle cell neoplasms. Little is known about its specificity for vascular differentiation. Read More

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Epidemiology and Survival of Dogs Diagnosed with Splenic Lymphoid Hyperplasia, Complex Hyperplasia, Stromal Sarcoma and Histiocytic Sarcoma.

Animals (Basel) 2022 Apr 8;12(8). Epub 2022 Apr 8.

School of Veterinary Science, University of Queensland, Gatton, QLD 4343, Australia.

Canine splenic fibrohistiocytic nodules traditionally encompassed benign lymphoid hyperplasia, complex hyperplasia, and malignant fibrous histiocytoma. The latter has been recently re-classified into histiocytic sarcoma and stromal sarcoma. Reliable indicators of post-splenectomy survival and demographic factors predisposing to the four types of nodules are not completely understood. Read More

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[A Case of Sclerosing Angiomatoid Nodular Transformation Resected for Suspected Relapse of Diffuse Large B-cell Lymphoma].

Gan To Kagaku Ryoho 2022 Apr;49(4):459-461

Dept. of Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center.

We report a case of sclerosing angiomatoid nodular transformation(SANT)5 years after remission of diffuse large B-cell lymphoma(DLBCL). A 64-year-old woman was diagnosed a nodular mass at the spleen by a contrast-enhanced CT scan 5 years after the relief for DLBCL. The mass showed accumulation of FDG. Read More

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Rare Palisading Variant of Dermatofibroma.

Am J Dermatopathol 2022 Jun 6;44(6):439-441. Epub 2022 Apr 6.

Pathology, Kaiser Permanente Los Angeles, Medical Center, Los Angeles, CA.

Abstract: Dermatofibromas (DFs) are benign lesions that typically present as firm papules or nodules on the legs of young- to middle-aged adults. DFs are histologically characterized by a dermal proliferation of spindled fibrohistiocytic cells forming intersecting fascicles and showing collagen entrapment. The palisading variant of DF was first described in 1986 and often presents as a dome-shaped nodule on the digits. Read More

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Sclerosing angiomatoid nodular transformation of the spleen: A case report.

Medwave 2022 Mar 28;22(2):e8710. Epub 2022 Mar 28.

Laboratorio de Psicometría, Psicología Comparada y Etología del Centro de Investigación, Innovación y Transferencia de Tecnología (CIITT) de la Universidad Católica de Cuenca, Ecuador. ORCID: 0000-0002-6996-0443.

Sclerosing angiomatoid nodular transformation is a benign vascular pathology of the spleen, developed from the red pulp, of unknown etiology; it is postulated that it may be related to IgG4 disease and Epstein-Barr virus infection. Most cases are asymptomatic, constituting incidental findings in imaging studies. We present a 41-year-old male patient with a history of thyroidectomy for papillary carcinoma who consulted for fever, received symptomatic treatment and performed a computed tomography of the abdomen for nonspecific abdominal symptoms, the same evidence in the lower pole of the spleen a solid-looking image with faint Peripheral enhancement with contrast, measures 62x 52x51 mm. Read More

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Lepromatous leprosy with dermatofibroma features: colonization or morphological variant of histoid leprosy with epidermal induction?

Int J Dermatol 2022 Mar 29. Epub 2022 Mar 29.

School of Medicine, Botucatu Medical School, Paulista State University (UNESP), Botucatu, São Paulo, Brazil.

Background: Leprosy is one of the main health problems in developing countries. It can show many different clinical presentations.

Case Report: A 37-yr-old woman with multiple reddish-brown papules on the lower and upper limbs, including the palms. Read More

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Multifocal Sclerosing Angiomatoid Nodular Transformation of the Spleen With Splenomegaly and Thrombocytopenia.

Balkan Med J 2022 Jan;39(1):73-75

Department of Radiology, Jiangsu Province Hospital of Chinese Medicine, Jiangsu, China.

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January 2022

Real-time high-resolution millimeter-wave imaging for in-vivo skin cancer diagnosis.

Sci Rep 2022 03 23;12(1):4971. Epub 2022 Mar 23.

Department of Electrical and Computer Engineering, Stevens Institute of Technology, 1 Castle Point Ter, Hoboken, NJ, 07030, USA.

High-resolution millimeter-wave imaging (HR-MMWI), with its high discrimination contrast and sufficient penetration depth, can potentially provide affordable tissue diagnostic information noninvasively. In this study, we evaluate the application of a real-time system of HR-MMWI for in-vivo skin cancer diagnosis. 136 benign and malignant skin lesions from 71 patients, including melanoma, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, melanocytic nevi, angiokeratoma, dermatofibroma, solar lentigo, and seborrheic keratosis were measured. Read More

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Diagnostic utility of ERG immunostaining in dermatofibroma.

J Clin Pathol 2022 Mar 22. Epub 2022 Mar 22.

Department of Anatomic Pathology, Kyushu University, Fukuoka, Japan

Aims: Dermatofibroma/fibrous histiocytoma (DF/FH) is a common cutaneous mesenchymal neoplasm exhibiting benign biological behaviour. However, the immunohistochemical utility of erythroblast transformation-specific-related gene (ERG) for diagnosing DF remains unknown. The authors reviewed the immunohistochemical status of ERG in different subtypes of DF and in its differential diagnoses. Read More

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Atrophic Dermatofibroma in a Young Female: A Rare Entity.

J Cutan Aesthet Surg 2021 Oct-Dec;14(4):446-448

Department of Dermatology, G. G. S. Medical College, Faridkot, Punjab, India.

Introduction: Atrophic dermatofibroma is a rare variant of dermatofibroma which is many times underdiagnosed.

Case Report: We report a case report of a 29-year-old female who came to the dermatology department with black-colored lesions on the lower leg for the past 7 years. Histopathological examination revealed a non-encapsulated dermal tumor involving upper to deep reticular dermis and extending to superficial subcutis. Read More

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JAAD Case Rep 2022 Mar 21;21:144-147. Epub 2022 Jan 21.

Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, Texas.

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Angiomatoid Fibrous Histiocytoma Mimicking a Lymph Nodal Lesion: A Case Report.

JNMA J Nepal Med Assoc 2022 Feb 15;60(246):200-203. Epub 2022 Feb 15.

Department of Radiology, B&B Hospital Pvt. Ltd., Gwarko, Lalitpur, Nepal.

Angiomatoid fibrous histiocytoma is an uncommon soft tissue neoplasm with potential for recurrence and rare metastasis. The majority of cases are painless, slow growing and occur in superficial extremities of young adults. Here we report a case of Angiomatoid fibrous histiocytoma in a 28-year-old male patient presenting as a slowly growing painful mass in the groin region. Read More

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February 2022

Absence of central white patch in dermatofibromas presenting in darker skin.

JAAD Case Rep 2022 Mar 6;21:63-65. Epub 2022 Jan 6.

University of Texas Health Science Center at San Antonio, Texas.

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Squamous Cell Carcinoma and Tattoo: A Man With a Tattoo-Associated Squamous Cell Carcinoma and Review of Benign Tumors, Lymphoid Conditions, and Malignant Neoplasms Occurring Within a Tattoo.

Authors:
Philip R Cohen

Cureus 2022 Jan 10;14(1):e21083. Epub 2022 Jan 10.

Dermatology, University of California, Davis Medical Center, Sacramento, USA.

Tattoos, a common form of body adornment, have been associated with numerous cutaneous complications. These include not only benign neoplasms and malignant tumors but also lymphoid conditions occurring within the tattoo. Tattoo-associated dermatomyofibroma, epidermoid inclusion cyst, hemangioma, lipoma, milia, and pilomatricoma are benign lesions that have each only been described in one individual. Read More

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January 2022

Dermoscopy in Primary Care.

Prim Care 2022 Mar 3;49(1):99-118. Epub 2022 Jan 3.

Department of Family and Community Medicine, Penn State Hersey Medical Center, 500 University Drive, Hersey, PA 17033, USA.

Dermoscopy is a noninvasive technique that allows in vivo magnification of the skin structures and helps in visualizing microscopic features that are imperceptible to the naked eye. Dermoscopy is not a substitute for biopsy and histopathologic evaluation, but is an important tool that can help increase diagnostic sensitivity and specificity of cutaneous lesions. Dermoscopy increases the diagnostic sensitivity compared with naked eye examination. Read More

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Preliminary Clinical Experience with a Novel Optical-Ultrasound Imaging Device on Various Skin Lesions.

Diagnostics (Basel) 2022 Jan 15;12(1). Epub 2022 Jan 15.

Dermus Ltd., Sopron út 64, 1116 Budapest, Hungary.

A compact handheld skin ultrasound imaging device has been developed that uses co-registered optical and ultrasound imaging to provide diagnostic information about the full skin depth. The aim of the current work is to present the preliminary clinical results of this device. Using additional photographic, dermoscopic and ultrasonic images as reference, the images from the device were assessed in terms of the detectability of the main skin layer boundaries and characteristic image features. Read More

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January 2022

[Rare tumor of the limbus: solitary benign fibrous histiocytoma].

Ophthalmologe 2022 01 17;119(1):1-2. Epub 2022 Jan 17.

Augenklinik, Universitätsklinikum Bonn, Bonn, Deutschland.

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January 2022

Dermoscopic features of aneurysmal dermatofibroma: A case report and review of the literature.

J Dermatol 2022 05 17;49(5):e169-e170. Epub 2022 Jan 17.

Department of Dermatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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Pleomorphic Appearance of Breast Cancer Cutaneous Metastases.

Authors:
Philip R Cohen

Cureus 2021 Dec 9;13(12):e20301. Epub 2021 Dec 9.

Dermatology, University of California, Davis Medical Center, Sacramento, USA.

Cutaneous metastases occur in approximately 10% of oncology patients as a feature of a persistent solid tumor or the harbinger of recurrent neoplastic disease. However, they can be the presenting manifestation of an unsuspected visceral malignancy in one percent of previously cancer-free individuals. Metastatic skin lesions from breast carcinoma are diverse in their appearance. Read More

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December 2021

[The most common benign cutaneous neoplasms of the epidermis and appendages and their treatment].

Hautarzt 2022 Feb 5;73(2):94-103. Epub 2022 Jan 5.

Colentina Krankenhaus, Abt. Dermatology II, "Carol Davila"-Universität für Medizin und Pharmazie, Bukarest, Rumänien.

Benign cutaneous neoplasms are well defined histologically with absence of all of the following features: architectural disorder, necrosis, cytologic atypia, and atypical mitotic figures. The clinical appearance of any neoplasm is a very important diagnostic factor. The classification of the lesion determines the therapeutic options. Read More

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February 2022

Recent advances in the diagnosis, classification and molecular pathogenesis of cutaneous mesenchymal neoplasms.

Histopathology 2022 Jan;80(1):216-232

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

The diagnosis of cutaneous mesenchymal neoplasms remains challenging, due to a combination of overlapping histological features, the rarity of some diagnoses and often inadequate sampling in superficial biopsies. Here, we describe recent advances in cutaneous mesenchymal neoplasms. We discuss improvements in our understanding of the molecular pathogenesis of non-neural granular cell tumour, epithelioid fibrous histiocytoma, composite and retiform haemangioendothelioma and dermatofibrosarcoma protuberans. Read More

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January 2022

Sclerosing angiomatoid nodular transformation of the spleen: a case report.

BMJ Case Rep 2021 Dec 23;14(12). Epub 2021 Dec 23.

Oncology Department, Nicosia General Hospital, Leukosia, Cyprus.

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is an uncommon primary benign condition with specific histopathological characteristics. The majority of the patients are usually asymptomatic and present for treatment after an incidental finding on a routine abdominal imaging. The differential diagnosis includes other benign tumours, as well as primary malignancy or metastases of unknown origin. Read More

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December 2021

Analyzing the morphological spectrum of epithelioid fibrous histiocytoma and the immunohistochemical performance of the ALK D5F3 and ALK1 clones.

Hum Pathol 2022 02 17;120:46-56. Epub 2021 Dec 17.

Douglass Hanly Moir Pathology, Sonic Healthcare, Macquarie Park, NSW 2113, Australia.

Epithelioid fibrous histiocytoma (EFH) is a cutaneous neoplasm driven by translocations of the anaplastic lymphoma kinase (ALK) gene, which can be demonstrated by immunohistochemical (IHC) analysis. We analyzed the performance of two ALK clones, D5F3 and ALK1, in a cohort of EFHs and described the range of architectural variation of these lesions. TFE3 IHC was performed in ALK-negative EFHs. Read More

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February 2022

Multinucleate Cell Angiohistiocytoma Treated With a 650 Microsecond Nd:YAG 1064 Laser.

Dermatol Surg 2022 Feb;48(2):259-261

Dermatology Institute & Laser Center, North Bergen, New Jersey.

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February 2022

Dermoscopic patterns and features of dermatofibroma in darker skin phototypes.

Int J Dermatol 2021 Nov 24. Epub 2021 Nov 24.

Dermatology Department, Universidad Autónoma de Nuevo León, Hospital Universitario, Monterrey, Nuevo León, México.

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November 2021

A rare case of aneurysmal dermatofibroma with distinct dermatoscopic findings.

J Cosmet Dermatol 2021 Nov 23. Epub 2021 Nov 23.

Department of Pathology, School of Medicine, Hacettepe University, Ankara, Turkey.

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November 2021

Spindle cell squamous cell carcinoma exhibiting a metaplasia to atypical fibroxanthoma.

J Dermatol 2022 Jan 16;49(1):e44-e45. Epub 2021 Nov 16.

Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.

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January 2022

Sclerosing Angiomatoid Nodular Transformation (SANT): A Rare Splenic Tumor and Unusual Cause of Anemia.

Am J Case Rep 2021 Nov 13;22:e933598. Epub 2021 Nov 13.

Upper Gastrointestinal Surgery, Lyell Mcewin Hospital, Adelaide, South Australia, Australia.

BACKGROUND Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign disease of the splenic red pulp of unknown etiology. Definite diagnosis is made on histopathology alone as it has no diagnostic radiologic characteristics. CASE REPORT We present a case of a large incidental splenic mass in a middle-aged man, whose refractory anemia resolved with splenectomy. Read More

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November 2021