6,661 results match your criteria Dermatofibroma

Adipophilin expression in skin lesions with clear cell histology.

J Clin Pathol 2021 May 5. Epub 2021 May 5.

Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Aims: Clear cells formed due to depositions of glycogen or lipids in the cytoplasm commonly occur in various tissues. Adipophilin (ADP), a lipid regulatory protein, is closely related to lipid droplets. This study aims to examine adipophilin expression in clear cells of various skin lesions. Read More

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Dermoscopic features of neoplasms in skin of color: A review.

Int J Womens Dermatol 2021 Mar 19;7(2):145-151. Epub 2021 Jan 19.

Emory University School of Medicine, Department of dermatology, 1525 clifton Rd NE, Atlanta, GA 30322.

Background: Dermoscopy is undoubtedly a useful tool to improve diagnostic accuracy and minimize the number of unnecessary biopsies. However, much of the literature on dermoscopy focuses on findings in lighter-skin phototypes, leaving potential gaps of knowledge regarding its use in skin of color (SoC). As the clinical applications of dermoscopy continue to increase, understanding dermoscopic patterns in SoC is imperative. Read More

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Skin Lesion Classification Using Additional Patient Information.

Biomed Res Int 2021 10;2021:6673852. Epub 2021 Apr 10.

Department of Dermatology, Shanghai Ninth Hospital affiliated to Shanghai Jiao Tong University, School of Medicine, No. 639, Manufacturing Bureau Road, Huangpu District, Shanghai 200011, China.

In this paper, we describe our method for skin lesion classification. The goal is to classify skin lesions based on dermoscopic images to several diagnoses' classes presented in the HAM (Human Against Machine) dataset: melanoma (MEL), melanocytic nevus (NV), basal cell carcinoma (BCC), actinic keratosis (AK), benign keratosis (BKL), dermatofibroma (DF), and vascular lesion (VASC). We propose a simplified solution which has a better accuracy than previous methods, but only predicted on a single model that is practical for a real-world scenario. Read More

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A Deep Learning Based Framework for Diagnosing Multiple Skin Diseases in a Clinical Environment.

Front Med (Lausanne) 2021 16;8:626369. Epub 2021 Apr 16.

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Numerous studies have attempted to apply artificial intelligence (AI) in the dermatological field, mainly on the classification and segmentation of various dermatoses. However, researches under real clinical settings are scarce. This study was aimed to construct a novel framework based on deep learning trained by a dataset that represented the real clinical environment in a tertiary class hospital in China, for better adaptation of the AI application in clinical practice among Asian patients. Read More

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Eyelid-Cheek Junction Soft-Tissue Perineurioma: Case Report and Controversies.

Ophthalmic Plast Reconstr Surg 2021 Apr 28. Epub 2021 Apr 28.

Division of Ophthalmology, McMaster University, Hamilton Faculty of Medicine, Canada Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada.

Perineurioma is a rare soft-tissue tumor with characteristic histologic and immunohistochemical features. The diagnosis; however, can be met with certain challenges. A 71-year-old woman presented with an enlarging painless mass in the right lower eyelid-cheek junction. Read More

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Dermatofibroma Transitioned to a Sclerotic Fibroma-Like Change Showing Delicate Reticulated Vessels in Dermoscopy.

Ann Dermatol 2020 Oct 29;32(5):432-434. Epub 2020 Sep 29.

Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.

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October 2020

Primary Cutaneous Solitary Fibrous Tumor on the Back.

Ann Dermatol 2020 Apr 11;32(2):155-158. Epub 2020 Mar 11.

Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea.

Solitary fibrous tumors (SFT) are uncommon mesenchymal tumors. SFT have several synonyms including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, and submesothelial fibroma. SFT usually occur in the pleura or other serosal surfaces, but SFT can also develop in extrapleural areas including the nasal cavity, orbit, retroperitoneum, and pelvis. Read More

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Reparative Perineural Hyperplasia in the Gastric Wall: A Histologic Mimic of Perineural Invasion.

Int J Surg Pathol 2021 Apr 28:10668969211013469. Epub 2021 Apr 28.

Institute of Pathology, Ljubljana, Slovenia.

Reparative perineural hyperplasia is an incidental and probably underreported reactive histologic finding thus far only reported in the setting of healing wounds or adjacent to a dermatofibroma in cutaneous specimens. It is characterized by a focal concentric proliferation of cytologically bland spindled perineurial cells and is hence considered a benign histologic mimic of neoplastic perineural invasion. Thus, it may present a diagnostic pitfall and we therefore consider it as a valuable entity to be aware of. Read More

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Benign fibrous histiocytoma of the maxilla: A rare case report and literature review.

Natl J Maxillofac Surg 2020 Jul-Dec;11(2):298-301. Epub 2020 Dec 16.

Department of ENT, Tata Main Hospital, Jamshedpur, Jharkhand, India.

Benign fibrous histiocytoma (FH) is a benign soft-tissue tumor that can present as a fibrous tissue mass anywhere in the body. The involvement of the paranasal sinuses is extremely rare, and very few cases have been reported in literature till date. We here report a case of benign FH localized in the maxillary sinus. Read More

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December 2020

Can ultrasound distinguish between dermatofibroma and subcutaneous epidermal tumors? - Imaging features and reproducibility.

Clin Imaging 2021 Apr 15;79:52-55. Epub 2021 Apr 15.

Department of Radiology, Inje University Ilsan Paik Hospital, Gyeonggi-do, Republic of Korea.

Background: We evaluated ultrasound (US) features of dermatofibroma and epidermal tumor (ET). We also evaluated the reproducibility of each US findings.

Materials And Methods: We retrospectively assessed US findings of 30 surgically confirmed dermatofibromas and 44 ETs, measuring the lesion (i. Read More

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Benign Umbilical Tumors Resembling Sister Mary Joseph Nodule.

Clin Med Insights Oncol 2021 24;15:1179554921995022. Epub 2021 Mar 24.

Department of Dermatology, School of Medicine, Pusan National University, Busan, South Korea.

Background: When physicians see an umbilical nodule, most of them instinctively recall the Sister Mary Joseph nodule. Therefore, dermatologists need to recognize umbilical dermatoses that can be mistaken for the Sister Mary Joseph nodules. This study aimed to describe the different kinds of benign umbilical tumors as well as elucidate the factors that can be used to distinguish the Sister Mary Joseph nodule from these tumors. Read More

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Hemosiderotic dermatofibroma mimicking melanoma: A case report and review of the literature.

Clin Case Rep 2021 Mar 26;9(3):1387-1392. Epub 2021 Jan 26.

Department of Pathology Creighton University School of Medicine Omaha NE USA.

Hemosiderotic dermatofibroma (HDF) often mimics melanoma clinically. A definite diagnosis relies on histopathological evaluation and immunohistochemistry. As it can progress to aneurysmal dermatofibroma (ADF), complete excision is recommended. Read More

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Conjunctival and Corneal Fibrous Histiocytoma: Brief review.

Semin Ophthalmol 2021 Mar 25:1-4. Epub 2021 Mar 25.

Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India.

Fibrous histiocytoma (FH), a mesenchymal tumour, usually have an orbital presentation. Rarely, FH in both benign and malignant forms have been reported at limbus and conjunctiva. Present narrative review was conducted to determine demographic profile, clinical presentation and management options for this rare tumour. Read More

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Perineuriomatous nevi: A series of eight cases highlighting unifying pathologic features to avoid misdiagnosis.

J Cutan Pathol 2021 Mar 21. Epub 2021 Mar 21.

Department of Pathology, Cleveland Clinic, Cleveland, Ohio, USA.

Background: Perineuriomatous nevi are rare and diagnostically problematic. We report a series of eight perineuriomatous nevi to highlight the diagnostic features.

Methods: Cases were retrospectively reviewed and characterized. Read More

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[Case report: Epigastric dermatofibroma reconstruction by reverse abdominoplasty with umbilic transposition].

Ann Chir Plast Esthet 2021 Mar 11. Epub 2021 Mar 11.

Service de chirurgie plastique, reconstructrice et esthétique, CHRU de Nancy, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France.

Dermatofibrosarcoma is the most common cutaneous sarcoma. Its surgical management is a technical challenge due to the high amount of substance loss. We explain a new technique of abdominal wall reconstruction by a reverse abdominoplasty with umbilical transposition. Read More

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Cholesterotic fibrous histiocytoma: Case report and literature review.

J Cutan Pathol 2021 Mar 12. Epub 2021 Mar 12.

Department of Dermatology, Park Nicollet Medical Groups, St. Louis Park, Minnesota, USA.

Cholesterotic fibrous histiocytoma is a particularly rare variant of dermatofibroma that is distinguished histopathologically by the presence of prominent cholesterol deposits within the lesion. We report the case of a 54-year-old male with poorly controlled hyperlipidemia who presented with a firm violaceous papule on the right shin, diagnosed as a cholesterotic fibrous histiocytoma. We also review and summarize the existing literature on this uncommon entity. Read More

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Molecular diagnosis of an atypical case of angiomatoid fibrous histiocytoma based on detection of the EWSR1 gene translocation.

J Dermatol 2021 May 23;48(5):e215-e216. Epub 2021 Feb 23.

Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

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Dermatofibroma Botryoides on Nipple: A Report.

Indian J Dermatol 2020 Nov-Dec;65(6):558-560

Department of Dermatology, Immunology, and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.

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January 2021

Soft tissue masses: distribution of entities and rate of malignancy in small lesions.

BMC Cancer 2021 Jan 22;21(1):93. Epub 2021 Jan 22.

Department of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.

Background: Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this study retrospectively investigated the distribution of histopathologic diagnosis to be encountered in small soft tissue tumors (≤ 5 cm) in a large series of a tertiary referral center.

Methods: Patients with a soft tissue mass (STM) with a maximum diameter of 5 cm presenting at our institution over a period of 10 years, who had undergone preoperative Magnetic resonance imaging and consequent biopsy or/and surgical resection, were included in this study. Read More

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January 2021

Paraneoplastic Secretion of Multiple Phosphatonins From a Deep Fibrous Histiocytoma Causing Oncogenic Osteomalacia.

J Clin Endocrinol Metab 2021 Apr;106(5):e2299-e2308

Singapore Institute for Clinical Sciences (A*STAR), Brenner Centre for Molecular Medicine, Singapore.

Context: Literature suggests that oncogenic osteomalacia is usually caused by a benign mesenchymal tumor secreting fibroblast growth factor subtype-23 (FGF-23), but the involvement of other phosphatonins has only been scarcely reported. We have previously published a seemingly typical case of oncogenic osteomalacia. Following curative neoplasm resection, we now report unique molecular characteristics and biology of this tumor. Read More

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A rare case of atrophic dermatofibroma with dermoscopic findings.

J Cosmet Dermatol 2021 Jan 6. Epub 2021 Jan 6.

Department of Dermatology, Health Science University Ümraniye Training and Research Hospital, Istanbul, Turkey.

Background: Dermatofibroma, also known as cutaneous benign fibrous histiocytoma, is a common skin tumour.

Aim: The aim of this paper was to present a rare variant of dermatofibroma, atrophic dermatofibroma, emphasizing histopathological and dermoscopic features.

Patients/methods: A case of atrophic dermatofibroma in a female patient with the characteristic histopathological features and newly demonstrated dermoscopic findings is presented. Read More

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January 2021

[Differential diagnosis dermatofibroma].

Hautarzt 2021 Jan 4. Epub 2021 Jan 4.

Univ.-Klinik für Dermatologie und Venerologie, Medizinische Universität Graz, Graz, Österreich.

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January 2021

A Deep Learning Approach to Skin Cancer Detection in Dermoscopy Images.

Ameri A

J Biomed Phys Eng 2020 Dec 1;10(6):801-806. Epub 2020 Dec 1.

PhD, Department of Biomedical Engineering, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

This work proposes a deep learning model for skin cancer detection from skin lesion images. In this analytic study, from HAM10000 dermoscopy image database, 3400 images were employed including melanoma and non-melanoma lesions. The images comprised 860 melanoma, 327 actinic keratoses and intraepithelial carcinoma (AKIEC), 513 basal cell carcinoma (BCC), 795 melanocytic nevi, 790 benign keratosis, and 115 dermatofibroma cases. Read More

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December 2020

Gadoxetic acid-enhanced MRI for differentiating hepatic sclerosing hemangioma from malignant tumor.

Eur J Radiol 2021 Feb 13;135:109474. Epub 2020 Dec 13.

Statistics and Data Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of Korea. Electronic address:

Background: To investigate the imaging features of gadoxetic acid-enhanced magnetic resonance imaging (MRI) to differentiate hepatic sclerosing hemangioma from malignant tumors.

Methods: This retrospective case-control study included 18 patients with sclerosing hemangioma and 54 patients with common hepatic malignant tumor, including hepatocellular carcinoma, metastatic adenocarcinoma, and cholangiocarcinoma, who were examined using gadoxetic acid-enhanced liver MRI from January 2008 to June 2019. Imaging features including signal intensity, tumor margins, enhancement pattern, and presence or absence of diffusion restriction were analyzed. Read More

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February 2021

Distinct clinicopathological features of pulmonary primary angiomatoid fibrous histiocytoma: A report of four new cases and review of the literature.

Thorac Cancer 2021 02 12;12(3):314-323. Epub 2020 Dec 12.

Department of Pathology, the Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Background: The aim of this study was to highlight the clinicopathological features of pulmonary primary angiomatoid fibrous histiocytoma (PPAFH) to assist with a differential diagnosis.

Methods: There were 10 previous reports in the literature and four new PPAFH cases reviewed in this study. Immunohistochemistry (IHC), fluorescence in situ hybridization (FISH) and DNA and RNA-based next-generation sequencing (NGS) was performed in the four new cases reported here. Read More

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February 2021

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Case Report.

Tokai J Exp Clin Med 2020 Dec 20;45(4):236-242. Epub 2020 Dec 20.

Department of Surgery, Tokai University Hachioji Hospital, 1838 Ishikawa-machi, Hachioji, Tokyo 192-0032, Japan.

Background: Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a non-tumorous benign lesion that originates in the spleen and It is rare.

Case Presentation: A 59-year-old man visited his physician for a checkup. Ultrasonography showed a mass in the spleen, and the patient was referred to our hospital. Read More

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December 2020

Rosettes in T-cell pseudolymphoma: a new dermoscopic finding.

An Bras Dermatol 2021 Jan-Feb;96(1):68-71. Epub 2020 Nov 16.

Department of Dermatology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Rosettes are small white structures visible with polarized light dermoscopy, whose exact morphological correlation is not yet defined. These small shiny structures are found in several conditions such as scarring, dermatofibroma, molluscum contagiosum, squamous cell carcinoma, basal cell carcinoma, melanoma, melanocytic nevus, discoid lupus erythematosus, and papulopustular rosacea. In this novel report, the authors describe the presence of rosettes in a T-cell pseudolymphoma lesion. Read More

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February 2021

Positive MITF and NKI/C3 Expression in Cellular Neurothekeoma and Dermatofibroma.

Appl Immunohistochem Mol Morphol 2020 Dec 1. Epub 2020 Dec 1.

Departments of Pathology.

Background: Cellular neurothekeoma (CNT) is a benign mesenchymal tumor with uncertain cellular differentiation. Studies have found evidence of myofibroblastic differentiation and possible relation to dermatofibromas (DFs). As microphthalmia transcription factor (MITF) and NKI/C3 stains are routinely positive in CNT, we compared expression patterns of both markers in CNT and DF to assess their relationship. Read More

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December 2020

Basal cell carcinoma in dermatofibroma: Dual diagnosis.

Aust J Gen Pract 2020 12;49(12):842-844

MBBS, FACD, FACRRM (Hon), Consultant Dermatologist, Mater Hospital, Qld; Senior Lecturer, University of Queensland, Qld.

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December 2020