6,479 results match your criteria Dermatofibroma


How reflectance confocal microscopy can help diagnose an enigmatic variant of dermatofibroma.

Dermatol Ther 2019 Feb 12:e12857. Epub 2019 Feb 12.

Dermatology Unit, Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1111/dth.12857DOI Listing
February 2019

Cellular Dermatofibroma: Clinicopathologic Review of 218 Cases of Cellular Dermatofibroma to Determine Clinical Recurrence Rate.

Dermatol Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, University of Utah, Salt Lake City, Utah.

Background: Cellular dermatofibromas, a variant of dermatofibroma, are reported to recur at rates of 26% to 50%.

Objective: To determine whether there are distinct clinical or histological differences between cellular dermatofibromas that recur versus those that do not. To determine recurrence rates in a real-world clinical setting. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001833DOI Listing
February 2019

Plaque-like myofibroblastic tumor, a rare entity of childhood: possible pitfalls in differential diagnosis.

J Cutan Pathol 2019 Feb 9. Epub 2019 Feb 9.

Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.

Plaque-like myofibroblastic tumor is a rare and benign pediatric soft tissue tumor. It presents as a slowly growing plaque reaching several centimeters in diameter, made up of multiple nodules. The clinical and histological features of this benign entity are similar to other fibrohistiocytic or myofibroblastic tumors occuring in childhood, so the diagnosis can be difficult. Read More

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http://dx.doi.org/10.1111/cup.13441DOI Listing
February 2019

Giant Dermatofibrosarcoma Protuberans With Bilateral Orbital Involvement.

Ophthalmic Plast Reconstr Surg 2019 Jan 25. Epub 2019 Jan 25.

Departments of Ophthalmology and Visual Sciences.

Dermatofibroma sarcoma protuberans (DFSP) is a rare, locally aggressive soft tissue sarcoma with a tendency for recurrence after excision. Although reports of unilateral orbital and bilateral eyelid disease exist, there have been no prior reports of DFSP with bilateral orbital involvement and no previously described cases of DFSP associated with transient optic neuropathy. The authors present a case report of a 34-year-old woman with a giant scalp DFSP involving the bilateral orbits. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001308DOI Listing
January 2019

Recurrent Dermatofibrosarcoma Protuberans of the Parotid: A case report and review of literature.

J Pak Med Assoc 2019 Jan;69(1):113-115

Aga Khan University Hospital, Karachi.

In 1924, Darier and Ferrand described Dermatofibrosarcoma Protuberans as a progressive and recurring dermatofibroma. It is a locally aggressive sarcoma originating from dermal and subdermal tissue of the skin. It usually begins as a small plaque that grows over a period and later manifests as multiple small subcutaneous nodules. Read More

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January 2019
2 Reads
0.403 Impact Factor

Teaching Benign Skin Lesions as a Strategy to Improve the Triage Amalgamated Dermoscopic Algorithm (TADA).

J Am Board Fam Med 2019 Jan-Feb;32(1):96-102

From Maine Medical Center, Division of Dermatology, Portland, ME (EVS); Department of Family & Community Medicine (HTA) and Department of Dermatology (AG, MB), Penn State Milton S. Hershey Medical Center, Hershey, PA; Dermatology Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain (OY); Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY (OY, SWD, AAM).

Introduction: Dermoscopy aids family physicians (FPs) in skin cancer detection. The triage amalgamated dermoscopic algorithm (TADA) was created to simplify the dermoscopic evaluation of a skin growth. The purpose of this image-based study was to evaluate the effect of teaching the clinical and dermoscopic features of benign skin lesions on the diagnostic accuracy of skin cancer identification using TADA. Read More

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http://www.jabfm.org/lookup/doi/10.3122/jabfm.2019.01.180049
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http://dx.doi.org/10.3122/jabfm.2019.01.180049DOI Listing
February 2018
11 Reads

Arthroscopic Resection for Benign Fibrous Histiocytoma in the Epiphysis of the Femur.

Case Rep Orthop 2018 18;2018:8030862. Epub 2018 Nov 18.

Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Japan.

A 16-year-old woman presented to her local hospital with a few-month history of right knee pain. On MRI, the lesion exhibited an intermediate signal on T1-weighted and T2-weighted images. The orthopedic physician made a diagnosis of osteochondritis dissecans. Read More

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http://dx.doi.org/10.1155/2018/8030862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276445PMC
November 2018
1 Read

Benign Solitary Fibrous Histiocytoma of Xanthomatous Subtype of the Perilimbal Conjunctiva and Adjacent Sclera in a Youth.

Ocul Oncol Pathol 2018 Nov 22;4(6):341-344. Epub 2018 May 22.

Department of Ophthalmology, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada.

Aims: To report the clinical and pathological features of a benign fibrous histiocytoma of the xanthomatous subtype in the perilimbal conjunctiva and adjacent sclera in a youth.

Methods: An 11-year-old Caucasian boy presented with a yellowish dome-shaped conjunctival mass abutting the inferotemporal limbus of the left eye. The tumor measured 4 mm in its maximum diameter. Read More

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http://dx.doi.org/10.1159/000486421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288713PMC
November 2018

Unusual Congenital Multiple Clustered Dermatofibroma: First Reported Case on the Face.

Acta Derm Venereol 2018 Dec 13. Epub 2018 Dec 13.

Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, 36-1 Nishicho, Yonago, Tottori 683-8504, Japan.

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http://dx.doi.org/10.2340/00015555-3109DOI Listing
December 2018
2 Reads

A white-bluish plaque with rapid growth after palpation.

Dermatol Pract Concept 2018 Oct 31;8(4):337-339. Epub 2018 Oct 31.

Department of Pathology, Hospital Universitario de Móstoles, Madrid, Spain.

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http://dx.doi.org/10.5826/dpc.0804a19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246067PMC
October 2018
1 Read

Dermoscopy of lipidised dermatofibroma: A morphological study of 13 cases.

Australas J Dermatol 2018 Nov 26. Epub 2018 Nov 26.

Dermatology Department, Hospital General Universitario de Alicante, Alicante, Spain.

Background/objectives: The aim of this study was to evaluate the morphological findings of lipidised dermatofibromas under dermoscopic observation.

Methods: Dermoscopic examination of 13 cases of lipidised dermatofibromas was performed to evaluate specific dermoscopic criteria and patterns.

Results: The most frequently occurring dermoscopic features were as follows: (i) A yellowish homogenous pigmentation in all cases (100%); this pigmentation was total in 30. Read More

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http://dx.doi.org/10.1111/ajd.12956DOI Listing
November 2018
2 Reads

Oral and Extraoral Intermediate Tumors: Are MMP-9 and Ki-67 Biomarkers Correlated to Their High Recurrence Rates?

Appl Immunohistochem Mol Morphol 2018 Oct 24. Epub 2018 Oct 24.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MA.

Intermediate tumors of the head and neck fall in the borderline category. They are clinically aggressive tumors with no malignant phenotyping. They are locally infiltrative and have high recurrence rate with less chances to metastasize. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000703DOI Listing
October 2018
6 Reads

Epithelioid Fibrous Histiocytoma: A Concise Review.

Am J Dermatopathol 2018 Oct 4. Epub 2018 Oct 4.

Laboratory Medicine, Department of Pathology, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH.

Epithelioid fibrous histiocytoma (EFH) is a rare lesion believed to arise from dermal microvascular unit fibroblasts and dendritic histiocytes. EFH has long been considered a morphologic variant of benign fibrous histiocytoma (dermatofibroma), with prominent epithelioid cytomorphology that can mimic both vascular and melanocytic neoplasms. The molecular basis for the relationship between EFH and benign fibrous histiocytoma has remained largely unknown, with some authors suggesting that EFH represents an entity that is biologically distinct from benign fibrous histiocytoma. Read More

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http://Insights.ovid.com/crossref?an=00000372-900000000-9826
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http://dx.doi.org/10.1097/DAD.0000000000001272DOI Listing
October 2018
8 Reads

Multiple cellular neurothekeomas in a middle-aged woman including the lower extremity: A case report and review of the current literature.

J Cutan Pathol 2019 Jan 8;46(1):67-73. Epub 2018 Nov 8.

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.

Cellular neurothekeoma is a benign cutaneous neoplasm that typically occurs on the head, neck, and upper body of young adults with a slight female predominance. It is a rare lesion to diagnose and multiple neurothekeomas in one patient are even more uncommon finding. We present a case of multiple neurothekeomas in a middle-aged woman with lower extremity involvement and summarize the current literature on multiple neurothekeoma patients. Read More

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http://doi.wiley.com/10.1111/cup.13366
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http://dx.doi.org/10.1111/cup.13366DOI Listing
January 2019
3 Reads

Plaque-like dermatofibroma with satellitosis in a young woman.

Int J Dermatol 2018 Sep 21. Epub 2018 Sep 21.

Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1111/ijd.14230DOI Listing
September 2018
1 Read

[Myxoid variant of angiomatoid fibrous histiocytoma: a clinicopathologic analysis of 3 cases].

Zhonghua Bing Li Xue Za Zhi 2018 Sep;47(9):700-705

Department of Pathology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

To study clinicopathologic features, diagnosis and differential diagnosis of myxoid variant of angiomatoid fibrous histiocytoma (AFH). Three cases of myxoid variant of AFHs were collected from First Affiliated Hospital of Nanjing Medical University during 2008 and 2017. EnVision method and fluorescence in situ hybridization(FISH) were used to detect immunophenotype and EWSR1 gene rearrangement, respectively. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.09.010DOI Listing
September 2018
5 Reads

Unique histopathologic features of the eyelid dermatofibroma.

Orbit 2018 Sep 5:1-5. Epub 2018 Sep 5.

a Edward Harkness Eye Institute , Columbia University Medical Center , New York , New York , USA.

Purpose: Dermatofibromas are common cutaneous lesions, but rarely occur in the eyelid skin. The reason for the low incidence in the palpebral skin has not been elucidated. In this study, we analyze the histopathologic features of an illustrative case of dermatofibroma and review previously published cases to determine whether eyelid dermatofibroma develops differently from the prototypical dermatofibroma. Read More

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http://dx.doi.org/10.1080/01676830.2018.1513045DOI Listing
September 2018
1 Read

Treatment of angiomatoid fibrous histiocytoma after unplanned excision: a case report.

BMC Res Notes 2018 Aug 31;11(1):628. Epub 2018 Aug 31.

Department of Orthopedic Surgery, Kindai University Hospital, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

Background: Angiomatoid fibrous histiocytoma (AFH) is a relatively uncommon soft tissue tumor of intermediate biologic potential. It occurs in subcutaneous regions of the extremities or the trunk, usually presenting in children or young adults. This is the first reported case of subcutaneous AFH that developed in the iliac region and was treated with an unplanned resection. Read More

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https://bmcresnotes.biomedcentral.com/articles/10.1186/s1310
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http://dx.doi.org/10.1186/s13104-018-3736-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119284PMC
August 2018
4 Reads

Ulcerated congenital plexiform fibrohistiocytic tumor: Case report and literature review.

Pediatr Dermatol 2018 Nov 31;35(6):e360-e362. Epub 2018 Aug 31.

Department of Dermatology, La Paz Hospital, Madrid, Spain.

A newborn boy presented with a progressively infiltrating and painful congenital ulcerated plaque on the back of his left foot. A partial excision was performed and histopathologic examination confirmed a diagnosis of a plexiform fibrohistiocytic tumor. This rare tumor usually appears in children and adolescents, with congenital presentations even more uncommon. Read More

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http://dx.doi.org/10.1111/pde.13652DOI Listing
November 2018
9 Reads

Plexiform fibrohistiocytic tumor: imaging features and clinical findings.

Skeletal Radiol 2019 Mar 25;48(3):437-443. Epub 2018 Aug 25.

Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

Objective: To describe the imaging features of plexiform fibrohistiocytic tumor and its associated clinical findings.

Materials And Methods: An institutional database was searched to identify all patients with a pathological diagnosis of plexiform fibrohistiocytic tumor. The electronic medical record was reviewed for relevant clinical data. Read More

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http://link.springer.com/10.1007/s00256-018-3050-1
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http://dx.doi.org/10.1007/s00256-018-3050-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344299PMC
March 2019
15 Reads

Atrophic dermatofibroma in an elderly male - a rarely described variant of a common lesion.

Dermatol Online J 2018 Jun 15;24(6). Epub 2018 Jun 15.

University of Texas McGovern Medical School at Houston, Houston, Texas.

Dermatofibroma frequently presents as a red-brown nodule on the extremities of the middle aged. Atrophic dermatofibroma is a rare variant that has been most commonly described as an atrophic depressed, erythematous lesion in females. The correct diagnosis of atrophic dermatofibroma is often hindered by its infrequent presentation. Read More

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June 2018
1 Read

Atypical Fibroxanthoma Arising in a Burn Scar Treated With Mohs Micrographic Surgery.

Dermatol Surg 2018 Sep;44(9):1229-1231

Department of Dermatology, Columbia University Medical Center, New York, New York.

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http://Insights.ovid.com/crossref?an=00042728-201809000-0001
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http://dx.doi.org/10.1097/DSS.0000000000001420DOI Listing
September 2018
3 Reads

Application of 3D-printed PEEK scapula prosthesis in the treatment of scapular benign fibrous histiocytoma: A case report.

J Bone Oncol 2018 Sep 2;12:78-82. Epub 2018 Aug 2.

Department of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi 710032, PR China.

Background: Bone benign fibrous histiocytoma (BFH) is an invasive primary bone tumor. When the local excision is not complete, the risk of recurrence is high, and hence, one-piece resection is necessary. The major challenge for clinicians is to reconstruct the bone after resection of the tumor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22121374183009
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http://dx.doi.org/10.1016/j.jbo.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092313PMC
September 2018
19 Reads

Asymptomatic heterogeneously black-pigmented plaque in a 58-year-old man: an unusual presentation of a melanoma mimicker.

Dermatol Pract Concept 2018 Jul 31;8(3):224-226. Epub 2018 Jul 31.

Dermatology Department, Pontificia Universidad Católica de Chile, Santiago, Chile.

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http://dx.doi.org/10.5826/dpc.0803a14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092082PMC
July 2018
2 Reads

Aneurysmal fibrous histiocytoma.

BMJ Case Rep 2018 Aug 14;2018. Epub 2018 Aug 14.

Plastic Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey.

Aneurysmal fibrous histiocytoma (AFH) is a type of fibrohistiocytic tumour. We present a case of a patient who presented with a skin papule on the thigh region. Histopathological examination following total excision of the lesion revealed an AFH. Read More

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http://dx.doi.org/10.1136/bcr-2018-225198DOI Listing
August 2018
4 Reads

[Dermatofibroma with sebaceous induction].

Ann Dermatol Venereol 2018 Oct 7;145(10):613-619. Epub 2018 Aug 7.

Cabinet de pathologie cutanée, 56, rue de la Roquette, 75011 Paris, France.

Background: Histiocytoma or dermatofibroma (DF) is a common benign skin tumour with several clinical and histopathological variants. Sebaceous induction overlying a dermatofibroma is rare and infrequently reported. Using a detailed clinical case, herein the semiological and dermoscopic features of this lesion are described and illustrated, and the differential diagnoses presented. Read More

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http://dx.doi.org/10.1016/j.annder.2018.04.011DOI Listing
October 2018
2 Reads

Aneurysmal fibrous histiocytomas with recurrent rearrangement of the PRKCD gene and LAMTOR1-PRKCD fusions.

J Cutan Pathol 2018 Dec 5;45(12):966-968. Epub 2018 Sep 5.

Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1111/cup.13339DOI Listing
December 2018
13 Reads

Clear Cell Dermatofibroma on the Chest Wall: A Case Report and Its Diagnostic Traps.

Indian Dermatol Online J 2018 Jul-Aug;9(4):265-267

Department of Pathology, SB University Training and Research Hospital, Antalya, Turkey.

Dermatofibromas are common lesions of the skin. Although they occur at any part of the body, they are most commonly observed on the lower legs of middle-aged women. The lesion comprises fibroblast-like cells, histiocytes, collagenous tissue, and blood vessels. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_289_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042182PMC
July 2018
1 Read

Giant aneurysmal benign fibrous histiocytoma (dermatofibroma).

J Cutan Pathol 2018 Oct 1;45(10):774-776. Epub 2018 Aug 1.

Department of Pathology, Stony Brook Medicine, Stony Brook, New York.

Aneurysmal benign fibrous histiocytomas are variants of dermatofibromas. These benign blood-filled lesions can mimic malignancies due to their rapid and recurrent growth. Our patient is a 42-year-old Caucasian female with a past medical history of morbid obesity, diabetes, and hypertension, who presented with a mass on her left shoulder for 5 years' duration. Read More

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http://doi.wiley.com/10.1111/cup.13314
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http://dx.doi.org/10.1111/cup.13314DOI Listing
October 2018
2 Reads

Sclerosing angiomatoid nodular transformation of the accessory spleen: A case report and review of literature.

Medicine (Baltimore) 2018 Jun;97(26):e11099

The First Affiliated Hospital of Dalian Medical University-Radiology Department, Liaoning, Dalian, China.

Rationale: Sclerosing angiomatoid nodular transformation (SANT) is a rare case which usually occurs in spleen, but our case occurs in accessory spleen.

Patient Concerns: We reported a case of a 27 year old man who was identified with an isodense mass in the left abdominal cavity by ultrasonicphysical examination without symptoms. Blood routine and tumor markers (alpha fetal protein, carcinoembryonic antigen, CA19-9, CA125) were normal. Read More

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http://dx.doi.org/10.1097/MD.0000000000011099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039677PMC
June 2018
17 Reads

Volar Papulonodules in a Patient With Seronegative Rheumatoid Arthritis: Answer.

Am J Dermatopathol 2018 Jul;40(7):536-537

Dermatology, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1097/DAD.0000000000000828DOI Listing
July 2018
12 Reads

Hemosiderotic dermatofibroma mimicking melanoma in a 12-year-old boy: a case report.

Clin Case Rep 2018 Jun 6;6(6):1006-1009. Epub 2018 Apr 6.

Department of Dermatology Aksaray University Training and Research Hospital Aksaray 68200 Turkey.

We report a case of hemosiderotic dermatofibroma presenting as a brown-black-colored nodule with peripheral extensions, which mimics melanoma. Histopathology showed completely benign features with no atypia or mitosis. Nodular extensions of childhood dermatofibromas may be related to the growth of the child not necessarily pointing to a malignant process. Read More

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http://dx.doi.org/10.1002/ccr3.1508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986033PMC
June 2018
3 Reads

Generalized multinucleate cell angiohistiocytoma with involvement of palms and soles: An unusual manifestation.

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):468-470

Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_557_17DOI Listing
November 2018
2 Reads

Dermatofibrosarcoma protuberans: A retrospective study of clinicopathologic features and related Akt/mTOR, STAT3, ERK, cyclin D1, and PD-L1 expression.

J Am Acad Dermatol 2018 Nov 22;79(5):843-852. Epub 2018 May 22.

Department of Pathology, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: Little is known regarding oncoproteins other than platelet-derived growth factor subunit B in dermatofibrosarcoma protuberans (DFSP). Moreover, the risk factors for worse prognosis are controversial.

Objective: We sought to determine the clinicopathologic features and key factors for adverse outcome in DFSP, including the implication of expression of protein kinase B (Akt)/mammalian target of rapamycin (mTOR), signal transducer and activator of transcription 3 (STAT3), extracellular signal regulated kinase (ERK), cyclin D1, and programmed death ligand 1 (PD-L1). Read More

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http://dx.doi.org/10.1016/j.jaad.2018.05.016DOI Listing
November 2018
27 Reads
4.449 Impact Factor

Microphthalmia-associated transcription factor (MiTF): Promiscuous staining patterns in fibrohistiocytic lesions is a potential pitfall.

Pathol Res Pract 2018 Jun 11;214(6):821-825. Epub 2018 May 11.

Department of Pathology & Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address:

Microphthalmia-associated transcription factor (MiTF) is used as a marker of melanocytic differentiation. However, MiTF immunoexpression has also been observed in histiocytes, macrophages, smooth muscle cells and fibroblasts, which raise the concern of fibrohistiocytic (FH) lesions being misdiagnosed as melanoma based on MiTF immunoreactivity. MiTF has been known to be positive in FH tumors, but this is the first study evaluating ninety-three fibrohistiocytic neoplasms to understand and delineate the staining pattern of MiTF in these tumors. Read More

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http://dx.doi.org/10.1016/j.prp.2018.05.001DOI Listing
June 2018
25 Reads
1.562 Impact Factor

Pigmented peduncule on the leg.

Cutis 2018 Apr;101(4):E9-E11

Dermatology Department, Complejo Asistencial Universitario de Palencia, Spain.

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April 2018
2 Reads

Painful violaceous nodule with peripheral hyperpigmentation.

Cutis 2018 Apr;101(4):E6-E8

Section of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

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April 2018
2 Reads

An enlarging pedunculated nodule on the shoulder of a 21-year-old man.

Clin Exp Dermatol 2018 Aug 14;43(6):738-741. Epub 2018 May 14.

Department of Histopathology, Warwick Hospital, Warwick, Warwickshire, UK.

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http://dx.doi.org/10.1111/ced.13550DOI Listing

Adenodermatofibroma possessing dilated glandular structures with eccrine features: A case study.

J Cutan Pathol 2018 Aug 8;45(8):623-628. Epub 2018 Jun 8.

Department of Dermatology, Kurume University School of Medicine, Kurume, Japan.

Adenodermatofibroma is a newly recognized variant of dermatofibroma characterized by dense proliferation of fibroblasts and histiocytes admixed with dilated glandular structures showing apocrine secretion. Only five cases of adenodermatofibroma have been reported to date. We report an additional case of adenodermatofibroma on the back of a 67-year-old female. Read More

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http://dx.doi.org/10.1111/cup.13279DOI Listing
August 2018
2 Reads

Epithelioid cell histiocytoma with SQSTM1-ALK fusion: a case report.

Diagn Pathol 2018 May 10;13(1):28. Epub 2018 May 10.

Pathology Project for Molecular Targets, the Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.

Background: Epithelioid cell histiocytoma (ECH), which is also known as epithelioid benign fibrous histiocytoma, has been classified as a rare variant of fibrous histiocytoma (FH). However, the recent detection of ALK protein expression and/or ALK gene rearrangement in ECH suggests that it might be biologically different from conventional FH.

Case Presentation: A 27-year-old male presented with nodule on his left foot, which had been present for 5 years. Read More

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http://dx.doi.org/10.1186/s13000-018-0704-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946425PMC
May 2018
4 Reads

Atypical cellular neurothekeoma: A potential diagnostic pitfall for benign and malignant spindle cell lesions in skin.

J Cutan Pathol 2018 Aug 12;45(8):619-622. Epub 2018 Jun 12.

David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

Cellular neurothekeomas (CNTs) are rare, benign cutaneous tumors that arise primarily on the head and neck, with a slight female predominance. CNTs with atypical features have been described, including those with an infiltrative growth pattern. Although CNTs with atypical features are benign, recognition of this entity can pose diagnostic challenges. Read More

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http://doi.wiley.com/10.1111/cup.13274
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http://dx.doi.org/10.1111/cup.13274DOI Listing
August 2018
4 Reads

Case for diagnosis. Multinucleated cell angiohistiocytoma.

An Bras Dermatol 2018 Mar;93(2):291-293

Hospital de Santarém EPE, Santarém, Portugal.

Multinucleate cell angiohistiocytoma is a rare idiopathic benign fibrohistiocytic and vascular proliferation usually presenting as multiple asymptomatic papules, red to violaceous in colour, primarily located on the extremities of middle-aged females. This entity is probably underdiagnosed due to the lack of recognition by clinicians and pathologists. We describe a patient with a multinucleate cell angiohistiocytoma of the face, a less frequent localization, in order to increase awareness of this entity and elucidate its clinical, histopathological, and immunohistochemistry features. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20186821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916412PMC
March 2018
3 Reads

Utility of Ber-EP4 and MOC-31 in Basaloid Skin Tumor Detection.

Appl Immunohistochem Mol Morphol 2018 Apr 7. Epub 2018 Apr 7.

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.

Ber-EP4 has been the traditional immunostain used for the detection of basaloid skin tumors. Recently, MOC-31 has shown be superior to Ber-EP4 in the detection of basosquamous basal cell carcinoma (BCC) and many centers are now using both Ber-EP4 and MOC-31 antibodies together to detect these lesions. The objective of this study was to compare the utility of using both Ber-EP4 and MOC-31 immunostains in the detection of basaloid skin tumors and to better characterize the previously unknown staining properties of MOC-31 in cutaneous lesions. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000664DOI Listing
April 2018
4 Reads

Rare experience of keloidal dermatofibroma of forehead.

Arch Craniofac Surg 2018 Mar 20;19(1):72-74. Epub 2018 Mar 20.

Department of Plastic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Dermatofibromas most commonly occur on limbs and rarely occur on the face. Dermatofibroma occurring on the face is associated with unusual clinicopathologic features and a more aggressive clinical course in comparison to typical cases. Additionally, the most common subtype found in previous studies was benign fibrous histiocytoma, with the keloid type being very rare (about 1% of reported cases). Read More

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http://dx.doi.org/10.7181/acfs.2018.19.1.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894553PMC

Dermoscopic Features of Basal Cell Carcinoma on the Lower Limbs: A Chameleon!

Dermatology 2017 22;233(6):482-488. Epub 2018 Mar 22.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Background: Lower limbs represent an uncommon location for basal cell carcinoma (BCC) and only few reports have described dermoscopic features of BCC in this body site. Since BCCs of the lower limbs frequently display nonclassic BCC dermoscopic criteria, they can simulate other benign or malignant lesions.

Objective: Our aim was to describe the dermoscopic features of BCC located on lower limbs and to define which criteria were more associated with their benign- or malignant-looking appearance. Read More

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http://dx.doi.org/10.1159/000487300DOI Listing
October 2018
4 Reads

Local depigmentation of a tattoo.

Cutis 2018 Jan;101(1):E8-E9

Department of Dermatology, Mayo Clinic, Scottsdale, Arizona, USA.

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January 2018
3 Reads

Giant cells in soft tissue tumors! Is it a clue to diagnosis or cytologists mystery??? An unusual case report.

J Cancer Res Ther 2018 Jan-Mar;14(2):444-446

Department of General Surgery, KS Hegde Medical Academy, KS Hegde Medical Academy, Nitte University, Mangalore, Karnataka, India.

Giant cells in soft tissue (ST) tumors are rare, pose great challenges to treating clinicians, and diagnosing pathologists. Common lesion with giant cells includes benign conditions such as nodular fasciitis to highly malignant lesions such as giant cell variant of malignant fibrous histiocytoma and extraskeletal osteosarcoma. Giant cell tumors of ST, extension of bony lesion to the ST are also rare possibilities. Read More

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http://dx.doi.org/10.4103/0973-1482.199433DOI Listing
August 2018
21 Reads

An enlarging nodule on the shin.

Clin Exp Dermatol 2018 Jul 6;43(5):627-629. Epub 2018 Mar 6.

Department of Dermatology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1111/ced.13417DOI Listing
July 2018
3 Reads