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    3131 results match your criteria Dermatitis Herpetiformis

    1 OF 63

    Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area.
    Acta Derm Venereol 2017 Oct 19. Epub 2017 Oct 19.
    Department of Dermatology, Tampere University Hospital, PO Box 2000, FIN-33521 Tampere, Finland.
    Dermatitis herpetiformis (DH) is an extra-intestinal manifestation of coeliac disease. The highest currently reported prevalence of DH is in Finland, but knowledge of diagnostic delay is limited. This study investigated the duration of rash prior to diagnosis in 446 patients with DH, analysing the results in 3 periods of 15 years. Read More

    A comparative study of expression of Fc receptors in relation to the autoantibody-mediated immune response and neutrophil elastase expression in autoimmune blistering dermatoses.
    Pol J Pathol 2017;68(2):109-116
    Here we investigated the cutaneous CD32A and CD89 expression in relation to the neutrophil elastase (NE) expression and serum level of anti-desmoglein 1 and 3 (DSG1/DSG3) IgG in pemphigus, anti-BP180/BP230 IgG in bullous pemphigoid (BP), anti-gliadin nonapeptides (npG), tissue (tTG), and epidermal transglutaminases (eTG) IgA in dermatitis herpetiformis (DH). The examined material consisted of skin/mucosal tissues and sera. In total, 87 patients were studied. Read More

    Recurrent impetigo herpetiformis: case report.
    Pan Afr Med J 2017 24;27:219. Epub 2017 Jul 24.
    Faculty of Health Sciences, Egerton University, Njoro, Kenya.
    Impetigo herpetiformis (pustular psoriasis of pregnancy) is a rare dermatosis of pregnancy that typically starts in the 2(nd) half of pregnancy and resolves postpartum. It may recur in subsequent pregnancies. I present a case of 23 year old female gravida 4 para 3 with recurrent impetigo herpetiformis at 26 weeks gestation. Read More

    Renal disease in patients with celiac disease: a review.
    Minerva Med 2017 Oct 3. Epub 2017 Oct 3.
    nd Department of Internal Medicine, University of Mississippi Medical Center, Jackson, MS, USA -
    Celiac disease, an inflammatory disease of small bowel caused by sensitivity to dietary gluten and related protein, affects approximately 0.5-1% of the population in the Western world. Extraintestinal symptoms and associated diseases are increasingly recognized including diabetes mellitus type 1, thyroid disease, dermatitis herpetiformis and ataxia. Read More

    A novel data-driven workflow combining literature and electronic health records to estimate comorbidities burden for a specific disease: a case study on autoimmune comorbidities in patients with celiac disease.
    BMC Med Inform Decis Mak 2017 Sep 29;17(1):140. Epub 2017 Sep 29.
    Georges Pompidou European Hospital (HEGP), AP-HP, Paris, France.
    Background: Data collected in EHRs have been widely used to identifying specific conditions; however there is still a need for methods to define comorbidities and sources to identify comorbidities burden. We propose an approach to assess comorbidities burden for a specific disease using the literature and EHR data sources in the case of autoimmune diseases in celiac disease (CD).

    Methods: We generated a restricted set of comorbidities using the literature (via the MeSH® co-occurrence file). Read More

    Transglutaminases in autoimmune and inherited skin diseases: The phenomena of epitope spreading and functional compensation.
    Exp Dermatol 2017 Sep 23. Epub 2017 Sep 23.
    University of Münster, Dept of Dermatology, Münster, Germany.
    Transglutaminases (TGs) are structurally and functionally related enzymes that modify the posttranslational structure and activity of proteins or peptides, and thus are able to turn on or switch off their function. Depending on location and activities, TGs are able to modify the signaling, the function and the fate of cells and extracellular connective tissues. Beside mouse models also human diseases enable us to appreciate the function of various TGs. Read More

    Declining trend in the incidence of biopsy-verified coeliac disease in the adult population of Finland, 2005-2014.
    Aliment Pharmacol Ther 2017 Dec 21;46(11-12):1085-1093. Epub 2017 Sep 21.
    Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
    Background: The frequency of coeliac disease (CD) has been on the rise over the past decades, especially in Western Europe, but current trends are unclear.

    Aim: To research the recent temporal changes in the incidence of adult, biopsy-verified coeliac disease and dermatitis herpetiformis (DH) in Finland, a country with a high frequency of coeliac disease.

    Methods: All coeliac disease and DH cases diagnosed at age 20-79 years during 2005-2014 were retrieved from a nationwide database documenting all applicants for monthly compensation to cover the extra cost of maintaining a gluten-free diet. Read More

    Disappearance of epidermal transglutaminase and IgA deposits from the papillary dermis of dermatitis herpetiformis patients after a long-term gluten-free diet.
    Br J Dermatol 2017 Sep 14. Epub 2017 Sep 14.
    Coeliac Disease Research Center, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
    Dermatitis herpetiformis (DH) is an itchy, blistering skin disease characterised by the deposition of granular immunoglobulin A (IgA) in the papillary dermis. It is regarded as the cutaneous manifestation of coeliac disease, an autoimmune-mediated condition affecting the small intestine. In addition to skin symptoms, DH patients have mostly subclinical small-intestinal villous atrophy and crypt hyperplasia or at least coeliac-type inflammatory changes. Read More

    Trichoscopy - a useful tool in the preliminary differential diagnosis of autoimmune bullous diseases.
    Int J Dermatol 2017 Oct 30;56(10):996-1002. Epub 2017 Aug 30.
    Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
    Background: Scalp is a common location of autoimmune bullous diseases. Trichoscopy is a noninvasive method for diagnosing hair and scalp diseases. Data on trichoscopy in autoimmune bullous diseases are limited to the studies on pemphigus including a small number of patients. Read More

    The Value of Direct Immunofluorescence on Proteinase-Digested Formalin-Fixed Paraffin-Embedded Skin Biopsies.
    Am J Dermatopathol 2017 Aug 9. Epub 2017 Aug 9.
    Department of Pathology, University of Massachusetts Medical School, UMass Memorial Medical Center, Worcester, MA.
    Direct immunofluorescence (DIF) on frozen tissue (DIF-F) is the method of choice for the identification of immune deposits present in skin and other tissues. DIF can also be performed on formalin-fixed paraffin-embedded tissue (DIF-P) after antigen retrieval with proteases and has proven to be of value in renal pathology. However, its utility in skin biopsies has not been fully examined. Read More

    The Role of Intereukin-31 in Pathogenesis of Itch and Its Intensity in a Course of Bullous Pemphigoid and Dermatitis Herpetiformis.
    Biomed Res Int 2017 20;2017:5965492. Epub 2017 Jul 20.
    Department of Dermatology and Venereology, Medical University of Lodz, Poland Hallera Square No. 1, 90-647 Lodz, Poland.
    Itch which is one of the major, subjective symptoms in a course of bullous pemphigoid and dermatitis herpetiformis makes those two diseases totally different than other autoimmune blistering diseases. Its pathogenesis is still not fully known. The aim of this research was to assess the role of IL-31 in development of itch as well as to measure its intensity. Read More

    Autoimmune Bullous Disease in Childhood.
    Indian J Dermatol 2017 Jul-Aug;62(4):440
    Department of Dermatology, School of Medicine, Marmara University, Istanbul, Turkey.
    Background: Autoimmune bullous disorders (AIBDs) are a heterogeneous group of diseases which are rarely seen in children. Studies concerning the immunobullous diseases in pediatric patients are scarce.

    Aims And Objectives: In this study, we aimed to investigate the clinical features and treatment outcomes of AIBDs in children. Read More

    Evaluation of Autoimmune Bullous Diseases in Elderly Patients in Iran: A 10-Year Retrospective Study.
    Skinmed 2017 1;15(3):175-180. Epub 2017 Jun 1.
    Department of Dermatology, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
    Autoimmune bullous diseases (ABDs) are uncommon but significant skin disorders with relatively high morbidity and mortality. Some surveys have been carried out to describe the spectrum of ABDs in a region, but this is the first that has focused on ABDs in elderly patients. This study was conducted to determine the clinicoepidemiologic features of ABDs in elderly patients. Read More

    Increased risk of herpes zoster in patients with coeliac disease - nationwide cohort study.
    Scand J Public Health 2017 Jul 1:1403494817714713. Epub 2017 Jul 1.
    6 Department of Health Management and Health Economy, Institute of Health and Society, University of Oslo, Norway.
    Background And Aims: Clinical experience suggests that patients with coeliac disease (CD) are more prone to develop herpes zoster (HZ), but robust studies are lacking.

    Methods: We identified 29,064 patients with CD 1969-2008 using biopsy report data from Sweden's 28 pathology departments. CD was equalled to villous atrophy (Marsh histopathology grade III). Read More

    Linear IgA bullous dermatosis mimicking oral lichen planus.
    Proc (Bayl Univ Med Cent) 2017 Jul;30(3):360-361
    Texas A&M Health Science Center College of Medicine (Shah, Parekh) and Department of Dermatology, Scott & White Memorial Hospital (Shah, Mohr, Parekh), Temple, Texas.
    Linear IgA bullous dermatosis (LABD) is an autoimmune disease characterized by blisters on the skin and mucous membranes. Polycyclic, grouped bullae on cutaneous skin are the most characteristic clinical feature of LABD. Lesions are often indistinguishable from bullous pemphigoid or may resemble dermatitis herpetiformis. Read More

    Lymphocytic duodenitis or microscopic enteritis and gluten-related conditions: what needs to be explored?
    Ann Gastroenterol 2017 31;30(4):380-392. Epub 2017 May 31.
    Section of Gastroenterology (Enzo Ierardi, Giuseppe Losurdo, Andrea Iannone, Annacinzia Amoruso, Michele Barone, Mariabeatrice Principi, Antonio Pisani, Alfredo Di Leo).
    Microscopic enteritis (ME) is characterized by abnormal infiltration of intraepithelial lymphocytes in intestinal mucosa. It was described as duodenal lymphocytosis or lymphocytic duodenitis until the dedicated Consensus Conference of 2015. ME represents a common feature of several gluten-mediated and non-gluten related diseases; therefore, it is an umbrella term embracing several conditions. Read More

    Extraintestinal Manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet.
    J Pediatr Gastroenterol Nutr 2017 Jul;65(1):75-79
    *Department of Pediatrics, University of Chicago Medicine Comer Children's Hospital, Chicago, IL †Department of Pediatrics, Università degli Studi di Verona, Verona, Italy.
    Objective: The aim of the study was to evaluate the effectiveness of the gluten-free diet (GFD) on extraintestinal symptoms in pediatric and adult celiac populations at the University of Chicago.

    Methods: We conducted a retrospective chart review of the University of Chicago Celiac Center clinic charts from January 2002 to October 2014. Demographics, serologic testing, intestinal biopsies, and extraintestinal symptoms at presentation, 12, 24, and >24 months were recorded. Read More

    Vesiculobullous variant of erythema elevatum diutinum.
    Clin Exp Dermatol 2017 Oct 22;42(7):777-780. Epub 2017 Jun 22.
    Unidad de Gestión Clínica Dermatología y Venereología, Hospital Universitario Puerta del Mar, Cádiz, Spain.
    The vesiculobullous variant of erythema elevatum diutinum (EED) is a very rare variant of EED. We describe a 16-year-old boy who presented with symmetrical nodular lesions accompanied by vesicles on the dorsa of his hands. Biopsy findings were consistent with EED. Read More

    Dermatitis Herpetiformis as the Initial Presentation of Primary Biliary Cholangitis in a Male with Gluten Sensitivity.
    Cureus 2017 May 14;9(5):e1247. Epub 2017 May 14.
    Gastroenterology, PVS Institute of Digestive Diseases, PVS Memorial Hospital.
    Celiac disease is commonly associated with elevated liver enzymes that normalize on a gluten-free diet. Celiac disease is rarely described in patients with primary biliary cholangitis. Dermatitis herpetiformis is the skin manifestation of the celiac disease that is very rarely associated with primary biliary cirrhosis. Read More

    Possible triggering factors and comorbidities in newly diagnosed autoimmune bullous diseases.
    Turk J Med Sci 2017 Jun 12;47(3):832-840. Epub 2017 Jun 12.
    Department of Dermatology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
    Background/aim: The distribution and the demographic, etiological, and clinical features of autoimmune bullous diseases (ABDs) vary according to geographic regions of the world. The limited number of reported studies in Turkey are mostly retrospective and generally include only pemphigus. The aim of our study was to evaluate the demographic data, clinical features, associated triggering factors, and comorbidities in patients newly diagnosed with ABDs. Read More

    Correlation between IL36α and IL17 and Activity of the Disease in Selected Autoimmune Blistering Diseases.
    Mediators Inflamm 2017 10;2017:8980534. Epub 2017 May 10.
    Department of Immunopathology, Chair of Allergy, Immunology and Dermatology, Medical University of Lodz, Lodz, Poland.
    Dermatitis herpetiformis (DH), bullous pemphigoid (BP), and pemphigus vulgaris (PV) are autoimmune bullous skin conditions with eosinophilic and neutrophilic infiltrations. While cytokines are crucial for the affinity and activation of different leukocyte cells in the inflammation and blister formation, there are no studies concerning a role of IL-36. The goal of the study was to analyze whether interleukin 36 is involved in pathogenesis of DH, BP, and PV. Read More

    Dermatitis herpetiformis and bone mineral density: analysis of a French cohort of 53 patients.
    Eur J Dermatol 2017 Aug;27(4):353-358
    Assistance Publique-Hôpitaux de Paris (APHP), Department of Dermatology, Henri Mondor Hospital, Créteil, France, EA 7379 EpiDermE (Epidémiologie en Dermatologie et Evaluation des Thérapeutiques), UPEC, Créteil, France, Université Paris-Est Créteil Val de Marne (UPEC), Créteil, France, Centre d'Investigation Clinique 1430, AP-HP, Créteil, France.
    The characteristics of patients with dermatitis herpetiformis (DH) in France is poorly documented. Furthermore, the risk of fractures and bone mineral density (BMD) in DH remain under-described, and recommendations for systematic screening for osteoporosis in DH are lacking. To describe the characteristics of DH in a large French cohort and evaluate the association between BMD and features of osteoporosis. Read More

    Celiac Disease Symptom Resolution: Effectiveness of the Gluten Free Diet.
    J Pediatr Gastroenterol Nutr 2017 May 16. Epub 2017 May 16.
    *Department of Pediatrics, University of Verona, Verona, Italy †Department of Pediatrics, Section of Gastroenterology, Hepatology, and Nutrition University of Chicago, Chicago, IL, USA ‡Department of Pediatrics, University of Chicago, Chicago, IL, USA.
    Objective: To evaluate the efficacy of the gluten free diet (GFD) on gastrointestinal and extra-intestinal symptom resolution and identify predictors for persistence of symptoms in all celiac patients at the University of Chicago.

    Methods: We conducted a retrospective chart review from 2002 to 2015. Gastrointestinal (GI) symptoms included: abdominal pain, bloating, constipation, diarrhea, failure to thrive/weight loss, nausea, reflux and vomiting. Read More

    A study of clinical, histopathological and direct immunofluorescence diagnosis in pemphigus group Utility of direct immunofluorescence.
    Bratisl Lek Listy 2017 ;118(4):243-249
    Aims: To determine the diagnostic accordance between histopathological and direct immunofluorescence diagnosis of patients with autoimmune vesiculobullous skin diseases.

    Background: The term pemphigus refers to a group of autoimmune blistering diseases mediated by auto-antibodies directed against desmoglein proteins. The differentiation between the various bullous diseases is important for treatment and prognosis. Read More

    Meeting Report of the Pathogenesis of Pemphigus and Pemphigoid Meeting in Munich, September 2016.
    J Invest Dermatol 2017 Jun 5;137(6):1199-1203. Epub 2017 Apr 5.
    Institute of Anatomy and Cell Biology, Ludwig-Maximilians-Universität, Munich, Germany.
    Autoimmune blistering diseases are a heterogeneous group of about a dozen complex disorders that are characterized by intraepidermal (pemphigus) and subepidermal blistering (pemphigoid diseases and dermatitis herpetiformis). The Pathogenesis of Pemphigus and Pemphigoid Meeting, organized by the Departments of Dermatology in Lübeck and Marburg and the Institute of Anatomy and Cell Biology, Munich, was held in September 2016 in Munich. The meeting brought together basic scientists and clinicians from all continents dedicating their work to autoimmune blistering diseases. Read More

    Short article: Mortality and differential diagnoses of villous atrophy without coeliac antibodies.
    Eur J Gastroenterol Hepatol 2017 May;29(5):572-576
    aFirst Department of Internal Medicine, Coeliac Centre Departments of bClinical Biochemistry cBiometry and Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Objective: Villous atrophy (VA) of the small bowel is mainly related to coeliac disease (CD), whose diagnosis is made on the basis of positive endomysial/tissue transglutaminase antibodies while on a gluten-containing diet in the vast majority of patients. However, VA can also occur in other conditions whose epidemiology is little known. Our aim was to study the epidemiology and clinical features of these rare enteropathies. Read More

    The Inpatient Burden of Autoimmune Blistering Disease in US Children: Analysis of Nationwide Inpatient Sample Data.
    Am J Clin Dermatol 2017 Apr;18(2):287-297
    Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Suite 1600, 676 N. St. Clair St., Chicago, IL, 60611, USA.
    Background: Little is known about the epidemiology of pediatric autoimmune blistering disorders (PAIBD).

    Objective: We sought to determine the inpatient burden and comorbidities of PAIBD.

    Methods: We analyzed data from the Nationwide Inpatient Sample from 2002 to 2012, which contained a representative 20% sample of all US hospitalizations. Read More

    Mortality and differential diagnoses of villous atrophy without coeliac antibodies.
    Eur J Gastroenterol Hepatol 2017 Jan 11. Epub 2017 Jan 11.
    aFirst Department of Internal Medicine, Coeliac CentreDepartments of bClinical BiochemistrycBiometry and Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Objective: Villous atrophy (VA) of the small bowel is mainly related to coeliac disease (CD), whose diagnosis is made on the basis of positive endomysial/tissue transglutaminase antibodies while on a gluten-containing diet in the vast majority of patients. However, VA can also occur in other conditions whose epidemiology is little known. Our aim was to study the epidemiology and clinical features of these rare enteropathies. Read More

    Rituximab Treatment for Recalcitrant Dermatitis Herpetiformis.
    JAMA Dermatol 2017 Mar;153(3):315-318
    Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
    Importance: Dermatitis herpetiformis (DH) is an autoimmune blistering condition seen in the context of celiac disease. While typically managed by gluten-free diet and dapsone, treatment of DH refractory to standard treatments is not well defined.

    Observations: A man in his 80s with DH not controlled by gluten-free diet (with poor adherence), dapsone, and conventional immune-suppressing agents responded to treatment with rituximab according to the lymphoma protocol (4 weekly infusions of 375 mg/m2). Read More

    Research Techniques Made Simple: Mouse Models of Autoimmune Blistering Diseases.
    J Invest Dermatol 2017 Jan;137(1):e1-e6
    Department of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany. Electronic address:
    Autoimmune blistering diseases are examples of autoantibody-mediated, organ-specific autoimmune disorders. Based on a genetic susceptibility, such as a strong HLA-class II association, as yet unknown triggering factors induce the formation of circulating and tissue-bound autoantibodies that are mainly directed against adhesion structures of the skin and mucous membranes. Compared with other autoimmune diseases, especially systemic disorders, the pathogenicity of autoimmune blistering diseases is relatively well described. Read More

    Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review.
    Case Rep Nephrol 2016 24;2016:6713807. Epub 2016 Nov 24.
    Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA.
    Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. Read More

    Cutaneous Manifestation of Food Allergy.
    Immunol Allergy Clin North Am 2017 Feb 28;37(1):217-231. Epub 2016 Oct 28.
    Division of Clinical Immunology and Allergy, Department of Pediatrics, Children's Hospital Los Angeles, 4650 Sunset Boulevard MS#75, Los Angeles, CA 90027, USA. Electronic address:
    Hypersensitivity reactions to foods can have diverse and highly variable manifestations. Cutaneous reactions, such as acute urticaria and angioedema, are among the most common manifestations of food allergy. However, cutaneous manifestations of food allergy encompass more than just IgE-mediated processes and include atopic dermatitis, contact dermatitis, and even dermatitis herpetiformis. Read More

    Are anti-epidermal transglutaminase (eTG) antibodies titre correlated with dermatitis herpetiformis lesions during the disease follow-up?
    G Ital Dermatol Venereol 2016 Nov 15. Epub 2016 Nov 15.
    Section of Dermatology, Di.S.Sal, AOU San Martino-IRCCS-IST, Genoa, Italy -
    Background: Dermatitis herpetiformis (DH) is characterized by the presence of anti-tissue transglutaminase (tTG) IgA antibodies in patient sera. In 2002, anti-epidermal transglutaminase (eTG) antibodies have been identified in DH patients. Nowadays, their role is still controversial. Read More

    Animal models to study non-celiac gluten sensitivity.
    Minerva Gastroenterol Dietol 2017 Mar 28;63(1):22-31. Epub 2016 Oct 28.
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA -
    Non-celiac gluten sensitivity (NCGS), sometimes known as non-celiac wheat sensitivity (NCWS), has recently received much attention, both scientific as well as from the alternative medical community. Over the past 5 years, there are over 200 publications on NCGS indexed on the PubMed database, the gluten-free market has been growing bigger, and it is clear that the number of consumers who are on a gluten-free diet (GFD) possibly because of a suspicion for NCGS appears to grow even faster. Nevertheless, despite these three rising events, many questions about NCGS remain unresolved. Read More

    Autoimmunity to heat shock proteins and vitamin D status in patients with celiac disease without associated dermatitis herpetiformis.
    J Steroid Biochem Mol Biol 2017 Oct 17;173:23-27. Epub 2016 Oct 17.
    Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
    Inflammation-induced heat shock proteins (HSPs) and hypovitaminosis D have been reported to impact immune responses and to be associated with autoimmune diseases including celiac disease (CD), a gluten-sensitive enteropathy mediated by autoantibodies against tissue transglutaminase (TG2). Recently, we provided evidence for a role of autoantibodies to HSPs in patients with dermatitis herpetiformis (DH), an inflammatory skin disease induced by underlying latent CD. In this study, we aimed at investigating the humoral autoimmune response to HSPs and vitamin D status in CD patients (n=15) presenting without the cutaneous disease manifestation. Read More

    Incidence of autoimmune bullous diseases in Serbia: a 20-year retrospective study.
    J Dtsch Dermatol Ges 2016 Oct;14(10):995-1005
    Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
    Background And Objectives: While most previous surveys on the clinico-epidemiological features of autoimmune bullous diseases (AIBDs) have predominantly focused on a single disease entity or just one disease group, there have been only few studies examining the incidence of various AIBDs. In the present study, we set out to determine the spectrum of AIBDs, to estimate the incidence of the most common AIBDs, and to examine their temporal trends in Central Serbia over a period of 20 years.

    Methods: We retrospectively recruited 1,161 new AIBD cases diagnosed in Central Serbia during the period from January 1991 to December 2010. Read More

    Inzidenz von bullösen Autoimmunerkrankungen in Serbien: eine retrospektive Studie über 20 Jahre.
    J Dtsch Dermatol Ges 2016 Oct;14(10):995-1006
    Institut für Sozialmedizin, Medizinische Fakultät, Universität Belgrad, Belgrad, Serbien.
    Hintergrund Und Ziele: Die meisten früheren Arbeiten zu den klinisch-epidemiologischen Merkmalen von bullösen Autoimmunerkrankungen (AIBD) konzentrierten sich vor allem auf eine einzige Krankheitsentität oder nur eine Krankheitsgruppe; nur in wenigen Studien wurde die Inzidenz verschiedener AIBD untersucht. Bei der vorliegenden Studie war es unser Ziel, das gesamte Spektrum der AIBD zu betrachten, die Inzidenz der häufigsten AIBD zu ermitteln und die zeitlichen Trends ihres Auftretens in Zentralserbien über einen Zeitraum von 20 Jahren zu untersuchen.

    Methoden: Wir rekrutierten retrospektiv 1161 AIBD-Fälle, die in Zentralserbien von Januar 1991 bis Dezember 2010 neu diagnostiziert wurden. Read More

    Extra-intestinal Manifestations of Celiac Disease: Effectiveness of the Gluten Free Diet.
    J Pediatr Gastroenterol Nutr 2016 Oct 13. Epub 2016 Oct 13.
    *Department of Pediatrics, University of Chicago Medicine Comer Children's Hospital, Chicago, IL †Department of Pediatrics, Università degli Studi di Verona, Verona, Italy.
    Objective: To evaluate the effectiveness of the GFD on extra-intestinal symptoms in pediatric and adult celiac populations at the University of Chicago (UofC).

    Methods: We conducted a retrospective chart review of the UofC Celiac Center clinic charts from January 2002 to October 2014. Demographics, serologic testing, intestinal biopsies, and extra-intestinal symptoms at presentation, 12, 24, and greater than 24 months were recorded. Read More

    Leading articles in medical journals in 1966.
    Br J Hosp Med (Lond) 2016 Oct;77(10):575-577
    ST7 in Clinical Pharmacology and Acute Medicine, University College London, London.
    The British Journal of Hospital Medicine is 50 years old. This article takes a look back at articles published during the year of its inception from the British Medical Journal, the Lancet and the Journal of the American Medical Association. Read More

    Effects of enzyme activities during steeping and sprouting on the solubility and composition of proteins, their bioactivity and relationship with the bread making quality of wheat flour.
    Food Funct 2016 Oct;7(10):4323-4331
    Institute for Multidisciplinary Research, University of Belgrade, Kneza Višeslava 1, 11030 Belgrade, Serbia.
    The aim was to determine the effect of steeping and sprouting on wheat grain proteins and the functional consequences in this regard. The solubility of proteins and the polypeptide composition of albumins, globulins, gliadins and glutenins were determined, as well as the content of non-protein nitrogen and free sulfhydryl groups (-SH), and the activity of peroxidase (POD) and lipoxygenase (LOX). In addition, the pasting viscosity of flour and protein bioactivity such as antioxidant capacity and immunoreactivity were evaluated. Read More

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