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    1 OF 738

    Interleukin 31 and skin diseases: A systematic review.
    Allergy Asthma Proc 2017 Nov;38(6):401-408
    Background: Although the pathophysiology of pruritus has been extensively studied in recent years, with many resultant advancements, management of pruritus is still enigmatic, particularly in chronic cutaneous diseases, such as atopic dermatitis, chronic urticaria, allergic contact dermatitis, cutaneous T-cell lymphoma, and uremic pruritus. The recent finding of the involvement of interleukin (IL) 31 in the pathogenesis of chronic pruritus has provided a novel approach to the management of chronic inflammatory skin disorders. The present report provided an in-depth overview of the role of IL-31 in chronic skin diseases and the possible diagnostic and therapeutic applications in the management of these diseases. Read More

    Contact dermatitis caused by a new rubber compound detected in canvas shoes.
    Contact Dermatitis 2017 Oct 17. Epub 2017 Oct 17.
    Department of Dermatology, University Hospital Gent, 9000, Ghent, Belgium.
    Background: In 2015 and 2016, female patients in Flanders consulted a dermatologist because they developed skin lesions after wearing a specific brand of canvas shoes.

    Objectives: To identify the culprit allergen in the shoes.

    Methods: Eighteen young females aged 14-22 years presented with itching and erythematous to purple-coloured eczematous lesions on both feet. Read More

    Dermal and neural toxicity caused by acrylamide exposure in two Korean grouting workers: a case report.
    Ann Occup Environ Med 2017 9;29:50. Epub 2017 Oct 9.
    Department of Occupational and Environmental Medicine, Dankook University College of Medicine, Cheonan, 201 Manghyang-ro, Dongnam-gu, Cheonan-si, Chungcheongnam-do 31116 Republic of Korea.
    Background: Peripheral neuritis caused by acrylamide is well-known, and many Korean grouting workers are frequently exposed to acrylamide in grouting agents that are injected into cracked concrete. We recently encountered two cases of dermal and neural toxicity in Korean grouting workers with exposure to grouting agents that contained a high concentration of acrylamide.

    Case Presentation: The first case involved a 44-year-old man with 8 years of waterproofing experience. Read More

    Molecular Mechanisms of Nickel Induced Neurotoxicity and Chemoprevention.
    Toxicology 2017 Oct 11. Epub 2017 Oct 11.
    Department of Preventative Medicine, Zhejiang Key Laboratory of Pathophysiology, Medicine School of Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province, 315211, People's Republic of China. Electronic address:
    Nickel (Ni) is widely used in many industrial sectors such as alloy, welding, printing inks, electrical and electronics industries. Excessive environmental or occupational exposure to Ni may result in tumor, contact dermatitis, as well as damages to the nervous system. In recent years, more and more research has demonstrated that Ni induced nerve damages are related to mitochondrial dysfunction. Read More

    Allergic Contact Dermatitis by Anatomical Regions: Diagnostic Clues.
    Actas Dermosifiliogr 2017 Oct 11. Epub 2017 Oct 11.
    Servicio de Dermatología, Hospital de la Sant Creu i Sant Pau, Barcelona, España.
    Allergic contact dermatitis (ACD) is a common disease in daily clinical practice, and its prevalence has increased in recent years. It is characterized clinically by varying degrees of erythema, vesiculation, flaking, and lichenification, though these signs can also be present in other eczematous diseases. Patch testing is the main diagnostic tool to confirm ACD, but its accurate interpretation requires correct correlation with the medical history (details of exposure) and physical examination. Read More

    Fragrance allergens linalool and limonene allylic hydroperoxides in skin allergy: mechanisms of action focusing on transcription factor Nrf2.
    Toxicol Sci 2017 Sep 29. Epub 2017 Sep 29.
    UMR996 - Inflammation, Chemokines and Immunopathology, INSERM, Univ Paris-Sud, Université Paris-Saclay, 92296, Châtenay-Malabry, France.
    Allergic contact dermatitis (ACD) is regarded as the most frequent expression of immunotoxicity in humans. Many odorant terpenes commonly used in fragrance compositions are considered as weak skin sensitizers, whereas some of their autoxidation products, allylic hydroperoxides, are classified as strong sensitizers according to the Local Lymph Node Assay (LLNA). However, the mechanism of their effects on the immune system remains unclear. Read More

    Most Common Dermatology Diagnoses to the Emergency Department in the Pediatric population.
    J Eur Acad Dermatol Venereol 2017 Oct 10. Epub 2017 Oct 10.
    Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
    Skin related complaints are a top 10 reason for pediatric presentation to the ED. Older studies and those conducted outside of the US demonstrate wide variability in the frequency of pediatric presentations to the ED for skin complaints, ranging from 4-40% of visits.(1) One study found urticaria to be the most frequent PED dermatological diagnosis, while others found viral exanthema and contact dermatitis to be the most common diagnoses. Read More

    Risks of Allergic Contact Dermatitis Elicited by Nickel, Chromium, and Organic Sensitizers: Quantitative Models Based on Clinical Patch Test Data.
    Risk Anal 2017 Oct 11. Epub 2017 Oct 11.
    Exponent Health Sciences, Bellevue, WA, USA.
    Risks of allergic contact dermatitis (ACD) from consumer products intended for extended (nonpiercing) dermal contact are regulated by E.U. Directive EN 1811 that limits released Ni to a weekly equivalent dermal load of ≤0. Read More

    Chemical Constituents of Bryophytes: Structures and Biological Activity.
    J Nat Prod 2017 Oct 11. Epub 2017 Oct 11.
    Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin , 20-093 Lublin, Poland.
    Comparatively little attention has been paid to the bryophytes for use in the human diet or medicine in spite of the presence of 23 000 species globally. Several hundred new compounds have been isolated from the liverworts (Marchantiophyta), and more than 40 new carbon skeletons of terpenoids and aromatic compounds were found. Most of the liverworts studied elaborate characteristic odiferous, pungent, and bitter-tasting compounds, of which many show antimicrobial, antifungal, antiviral, allergic contact dermatitis, cytotoxic, insecticidal, anti-HIV, plant growth regulatory, neurotrophic, NO production and superoxide anion radical release inhibitory, muscle relaxing, antiobesity, piscicidal, and nematocidal activities. Read More

    Contact dermatitis on the lower eyelid related to tick infestation: A case report in Taiwan.
    Taiwan J Ophthalmol 2016 Oct-Dec;6(4):201-203. Epub 2016 Jul 16.
    Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.
    Tick bite on the lower eyelid is a rare condition. We reported a case of contact dermatitis on the lower eyelid related to the tick infestation. Ticks are vectors for disease transmission. Read More

    Diagnosis and management of diaper dermatitis in infants with emphasis on skin microbiota in the diaper area.
    Int J Dermatol 2017 Oct 6. Epub 2017 Oct 6.
    Faculty of Medicine, Department of Pediatrics, University of Maribor, Maribor, Slovenia.
    Diaper dermatitis is the most common inflammatory skin eruption within the diaper area in infants and toddlers. Although it rarely causes problems for prolonged periods of time, it causes considerable distress for both infants and parents. Diapered skin is exposed to friction, excessive hydration, varying pH, and is in constant contact with urine and feces, both of which are highly irritant to the skin. Read More

    In vitro effects of polyphenols on the peripheral immune responses in nickel-sensitized patients.
    Endocr Metab Immune Disord Drug Targets 2017 Oct 3. Epub 2017 Oct 3.
    Department of Biomedical Sciences and Human Oncology, University of Bari, School of Medicine, Bari. Italy.
    Background: Nickel (Ni) is a metal largely present in the environment and prolonged exposure to it may lead to multiple pathological conditions in human subjects. Among these, the most frequent is allergic contact dermatitis.

    Methods: Peripheral blood mononuclear cells isolated from 25 patients with Ni-dependent contact dermatitis were evaluated in terms of cytokine release and nitric oxide (NO) production in the presence or absence of two doses (3 and 5 μg, respectively) of polyphenols. Read More

    Proteome Analysis of Urticating Setae From Thaumetopoea pityocampa (Lepidoptera: Notodontidae).
    J Med Entomol 2017 Jul 21. Epub 2017 Jul 21.
    Department of Agronomy Food Natural Resources Animals and Environment (DAFNAE), University of Padova, Viale dell'Universita 16, 35020 Legnaro, Padova, Italy.
    Thaumetopoea pityocampa (Denis & Schiffermüller) (Lepidoptera: Notodontidae) is harmful to conifer trees because of defoliation and to public health because of the release of urticating setae from the caterpillars. Contact with setae by humans and domestic animals induces dermatitis, usually localized to the exposed areas. Recent studies demonstrated the presence of a complex urticating mechanism where proteins present in the setae may play a role as activators of immune responses. Read More

    Paederus Dermatitis: A Case Series.
    Indian Dermatol Online J 2017 Sep-Oct;8(5):361-364
    Department of Dermatology, Venereology and Leprology, JSS Medical College and Hospital, Mysuru, Karnataka, India.
    Vorderman (1901) was the first to record blisters caused by beetles in medical literature. Blister beetle dermatitis is a cutaneous condition caused by the toxins released by blister beetles. The vesicant chemical in the body fluids of these insects causes an acute irritant contact dermatitis characterized by erythematovesicular lesions associated with burning sensation on exposed parts of the body. Read More

    Patch Testing in Patients with Suspected Footwear Dermatitis: A Retrospective Study.
    Indian Dermatol Online J 2017 Sep-Oct;8(5):323-327
    Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.
    Background: Footwear dermatitis represents a common but often undiagnosed or misdiagnosed condition. Patch testing aids in its confirmation and identification of the offending allergen.

    Aims: This study aimed to find the frequency of positive patch test reactions in cases with suspected allergic contact dermatitis (ACD) to footwear, as well as the common responsible allergens. Read More

    Dust mite induces multiple polar T-cell axes in human skin.
    Clin Exp Allergy 2017 Oct 4. Epub 2017 Oct 4.
    Department of Dermatology, Icahn School of Medicine at Mount Sinai, NY, USA.
    Background: House dust mite/HDM atopy patch test/APT elicits positive reactions in a high fraction of atopic dermatitis/AD and healthy individuals. Experimental systems for new-onset/chronic AD are needed to support rapid therapeutic development, particularly since animal models representing human AD are lacking. While HDM APT has been considered to simulate AD, its suitability to model AD's emerging Th2/Th22 phenotype with Th1 and Th17 components is unknown. Read More

    The Cooperative Role of CD326(+) and CD11b(+) Dendritic Cell Subsets for a Hapten-Induced Th2 Differentiation.
    J Immunol 2017 Oct 2. Epub 2017 Oct 2.
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea
    Dendritic cells (DCs) play a critical role in directing immune responses. Previous studies have identified a variety of DC subsets and elucidated their context-dependent functions that parallel those of effector Th cell subsets. However, little is known about the DC subsets responsible for differentiation of Th2 cells governing allergic contact dermatitis. Read More

    Prospective Single-Center Observational Study of the Allergenic Potential of Mercromina Film and Other Common Antiseptics in Patients With Contact Dermatitis.
    Actas Dermosifiliogr 2017 Sep 29. Epub 2017 Sep 29.
    Departamento de Dermatología, Hospital Clínic Barcelona, Universitat de Barcelona, Barcelona, España.
    Introduction: Although Mercromina Film and other topical antiseptics are widely used, they are not included in the standard series recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group for testing suspected allergic contact dermatitis (ACD). Furthermore, no recent studies have investigated the allergenic potential of merbromin.

    Objective: To determine the allergenic potential of merbromin and compare it with that of other topical antiseptics widely used in clinical practice, including povidone-iodine, chlorhexidine, and eosin. Read More

    Patch Test Results from an Occupational and Contact Dermatitis Clinic in a Tertiary Care Hospital of Southern India: A Retrospective Study.
    J Clin Diagn Res 2017 Aug 1;11(8):WC11-WC14. Epub 2017 Aug 1.
    Resident, Department of Dermatology, Madras Medical College, Chennai, Tamil Nadu, India.
    Introduction: Occupational contact dermatitis, accounting for 95% of cases of occupational dermatoses, is the most common occupational skin disease.

    Aim: To find out the various allergens in different occupational and environmental settings causing contact allergy, from our patients presented with contact dermatitis.

    Materials And Methods: It was a retrospective study from the data in hospital outpatient register over one year period, which includes patients with age ranging from 11 years to 73 years. Read More

    Skin antisepsis with 0.05% sodium hypochlorite before central venous catheter insertion in neonates: A 2-year single-center experience.
    Am J Infect Control 2017 Sep 26. Epub 2017 Sep 26.
    Neonatal Intensive Care Unit, Department of Women's and Children's Health, Maggiore Hospital, Bologna, Italy.
    Aim: The study reports a 2-year single-center experience of the practice of skin antisepsis using a 0.05% sodium hypochlorite solution before central venous catheter placement in neonates.

    Methods: Eligible subjects included any hospitalized neonate who needed a central line for at least 48 hours. Read More

    Evaluation of hyaluronic acid-P40 conjugated cream in a mouse model of dermatitis induced by oxazolone.
    Exp Ther Med 2017 Sep 19;14(3):2439-2444. Epub 2017 Jul 19.
    Department of Medicine and Health Sciences, University of Molise, I-86100 Campobasso, Italy.
    P40 is a particulate fraction or fragment isolated from Corynebacterium granulosum, which exhibits a wide spectrum of pharmacological functions including antitumor, antibacterial, phagocytic, antiviral and cytokine induction effects. In the present study, the immunomodulatory potential of P40-conjugated with hyaluronic acid was assessed in a mouse model of dermatitis induced by oxazolone. Oxazolone-induced allergic contact dermatitis is a T cell-mediated Th2-like hypersensitivity reaction, which mimics the corresponding reaction in humans. Read More

    Self-testing for contact allergy to hair dyes - a 5-year follow-up multicentre study.
    Contact Dermatitis 2017 Sep 29. Epub 2017 Sep 29.
    The National Allergy Research Centre, Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte, 2900, Hellerup, Denmark.
    Background: In 2011, a multicentre study was conducted in order to determine how hair dye manufacturers instructed consumers to perform a self-test prior to dyeing their hair, in order to identify individuals who are likely to react upon subsequent hair dyeing. A number of concerns were raised concerning the variability in instructions between products and producers, and the safety and validity of this tool.

    Objectives: To perform a 5-year follow-up study in order to determine whether manufacturers still recommend a self-test, and if so, whether the procedures have been changed. Read More

    Wearable health device dermatitis: a case of acrylate-related contact allergy.
    Cutis 2017 Aug;100(2):97-99
    Section of Dermatology, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, USA.
    The popularity of mobile wearable health devices has skyrocketed. Some of these devices are worn on the wrist and have been associated with the development of allergic contact dermatitis. Although nickel has been the suspected culprit in cases reported by the media for consumers, we present a rare report of a patient who developed a localized contact dermatitis that was linked to acrylate allergy on epicutaneous patch testing. Read More

    Are the Spanish baseline series markers sufficient to detect contact allergy to corticosteroids in Spain? A GEIDAC prospective study.
    Contact Dermatitis 2017 Sep 27. Epub 2017 Sep 27.
    Dermatology Department, Hospital General de Alicante, 03010, Alicante, Spain.
    Background: Corticosteroids are among the most commonly used topical drugs. Contact allergy to these exists, but can be easily missed. Corticosteroid screening markers have been included in the baseline series with the aim of detecting most of the sensitized patients. Read More

    The association of smoking with contact dermatitis and hand eczema - a review.
    Int J Dermatol 2017 Sep 27. Epub 2017 Sep 27.
    Department of Dermatology, Saint Louis University School of Medicine, St. Louis, MO, USA.
    Given the high prevalence of allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), hand eczema (HE), and smoking, and the impact that smoking has on skin disease, the authors reviewed the existing literature to assess the association between smoking and contact dermatitis or hand eczema. Using the PubMed and SCOPUS databases, a literature search identified articles related to allergic contact dermatitis, irritant contact dermatitis, and hand eczema and a possible association with smoking. The search period included articles prior to and including April 2016. Read More

    Behçet's disease: review with emphasis on dermatological aspects.
    An Bras Dermatol 2017 Jul-Aug;92(4):452-464
    Contact Dermatitis Outpatient Clinic - Dermatology Division at the Hospital das Clínicas - Universidade Federal de Minas Gerais (UFMG) - Belo Horizonte (MG), Brazil.
    Behçet's disease is a systemic vasculitis characterized by attacks of acute inflammation, which can affect almost every vascularized area of the body. There is a close correlation between the geographical distribution of HLA-B51 and its prevalence. In the etiopathogenesis there are indications of genetic susceptibility associated with environmental influence. Read More

    The role of nickel allergy in hand dermatitis and its impact on handling cupronickel currency coins. A comparative cohort study from Kuwait.
    Postepy Dermatol Alergol 2017 Aug 1;34(4):313-321. Epub 2017 Aug 1.
    Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait.
    Introduction: Contact with nickel-releasing coins as a cause of hand dermatitis has been debated.

    Aim: Studying a hand dermatitis risk from handling Kuwaiti cupronickel coins among nickel-allergic and nickel non-allergic subjects.

    Material And Methods: One hundred hand dermatitis patients (group I: nickel-allergic) and 100 matched patients (group II: nickel non-allergic) were selected from over 500 hand dermatitis cases seen between September 2014 and September 2015. Read More

    Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization.
    Toxicol In Vitro 2017 Sep 21;46:77-85. Epub 2017 Sep 21.
    Institute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, Berlin, Germany. Electronic address:
    Human cell-based approaches to assess defined key events in allergic contact dermatitis (ACD) are well-established, but lack cutaneous penetration and biotransformation as well as cellular cross-talk. Herein, we integrated in vitro-generated immature MUTZ-3-derived Langerhans-like cells (MUTZ-LCs) or monocyte-derived LC-like cells (MoLCs) into reconstructed human skin (RHS), consistent of a stratified epidermis formed by primary keratinocytes on a dermal compartment with collagen-embedded primary fibroblasts. LC-like cells were mainly localized in the epidermal compartment and distributed homogenously in accordance with native human skin. Read More

    Contact dermatitis caused by tulips: identification of contact sensitizers in tulip workers of Kashmir Valley in North India.
    Contact Dermatitis 2017 Sep 21. Epub 2017 Sep 21.
    Department of Dermatology, Sexually Transmitted Diseases & Leprosy, Government Medical College and Associated Hospitals, 190010, Srinagar, India.
    Background: Tulip, belonging to the genus Tulipa and family Liliaceae, is a spring-blooming perennial that grows from bulbs. Owing to manual handling, contact dermatitis can occur in professionals at any stage of the growth cycle of the tulip plant.

    Objectives: To determine the clinical pattern of contact dermatitis resulting from tulip plant cultivation, and to assess contact allergy in workers coming into contact with this plant. Read More

    When should the diagnosis 'contact urticaria' be used?
    Contact Dermatitis 2017 Sep 21. Epub 2017 Sep 21.
    Occupational Medicine, Finnish Institute of Occupational Health, PO Box 40, 00251 Helsinki, Finland.
    In the dermatological literature, the term 'contact urticaria syndrome' is often used with patients presenting no symptoms of contact urticaria, but symptoms of adjacent mucous membranes evolving to a systemic allergic reaction. Contact urticaria refers to a wheal and flare reaction following external contact with a causative substance. Its use should be restricted to skin: a skin reaction after direct skin contact. Read More

    Contact allergy to lanolin: temporal changes in prevalence and association with atopic dermatitis.
    Contact Dermatitis 2017 Sep 21. Epub 2017 Sep 21.
    Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark.
    Background: Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases.

    Objectives: To investigate the temporal development of lanolin allergy (i. Read More

    TLR7/8 agonists stimulate plasmacytoid dendritic cells to initiate a Th17-deviated acute contact dermatitis in humans.
    J Allergy Clin Immunol 2017 Sep 18. Epub 2017 Sep 18.
    Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
    Background: A standardized human model to study early pathogenic events in psoriasis is missing. Activation of Toll-like receptor 7/8 by topical application of imiquimod is the most commonly used mouse model of psoriasis.

    Objective: To investigate the potential of a human imiquimod patch test model to resemble human psoriasis. Read More

    Contact Dermatitis Reaction to 2-Octyl Cyanoacrylate Following 3 Orthopedic Procedures.
    Orthopedics 2017 Sep 21:1-3. Epub 2017 Sep 21.
    Two-octyl cyanoacrylate is a popular skin adhesive used for closing surgical incisions. Since Food and Drug Administration approval in 1998, the few reports of adverse reactions following its use have primarily been limited to the nonorthopedic literature. The authors present a case series of contact dermatitis associated with 2-octyl cyanoacrylate following orthopedic surgery and a review of the literature on the diagnosis and treatment of this complication. Read More

    Musical Instrument-Associated Health Issues and Their Management.
    Tohoku J Exp Med 2017 ;243(1):49-56
    Department of Cardiovascular Surgery, Tokyo Women's Medical University.
    Playing musical instruments can bring joy to people, but can also cause a wide variety of health issues that range from mild disorders to potentially fatal conditions. Although sports medicine is an established medical subspecialty, relatively few studies have investigated the health issues associated with musical instruments. Here we present an overview of these health issues. Read More

    [A case with scalp pruritus caused by Dermanysus gallinae (order: mesostigmata)].
    Mikrobiyol Bul 2017 Jul;51(3):293-298
    Pamukkale University Faculty of Medicine, Department of Medical Microbiology, Denizli, Turkey.
    Dermanyssus gallinae is one of the important hematophagous ectoparasite species of poultry like chicken, pigeon and wild bird species. These ectoparasites in the form of nymphs or adults who can not find their hosts are also seen in mammals and even in humans. For this reason, they are considered as important for public health. Read More

    Epidermal overexpression of xenobiotic receptor PXR impairs the epidermal barrier and triggers Th2 immune response.
    J Invest Dermatol 2017 Sep 16. Epub 2017 Sep 16.
    Department of Dermatology, Venereology and Allergology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address:
    The skin is in daily contact with environmental pollutants, but the long-term effects of such exposure remain under-investigated. Many of these toxins bind and activate the pregnane x receptor (PXR), a ligand-activated transcription factor that regulates genes central to xenobiotic metabolism. The objective of this work was to investigate the effect of constitutive activation of PXR in the basal layer of the skin to mimic repeated skin exposure to noxious molecules. Read More

    Contact dermatitis caused by methacrylates in nail products.
    CMAJ 2017 09;189(37):E1193
    Doctor of Medicine Program (DeKoven), Schulich School of Medicine and Dentistry, London, Ont.; Division of Occupational Medicine (DeKoven, Holness), Department of Medicine, St. Michael's Hospital; Dalla Lana School of Public Health and Department of Medicine (Holness), University of Toronto; Centre for Urban Health Solutions (Holness), Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ont.

    A Case of a Paediatric Patient With Allergic Contact Dermatitis to Benzoyl Peroxide.
    J Cutan Med Surg 2017 Sep 1:1203475417733462. Epub 2017 Sep 1.
    1 Division of Dermatology, University of Toronto, Toronto, ON, Canada.
    Allergic contact dermatitis to benzoyl peroxide can occur in up to 6.5% of those with a history of exposure to this potential allergen. Conversely, irritant contact dermatitis is very common with benzoyl peroxide and can be differentiated from allergic contact dermatitis based on the patient's history and clinical signs and symptoms. Read More

    Primary photosensitization and contact dermatitis caused by Malachra fasciata Jacq. N.V. (Malvaceae) in sheep.
    Toxicon 2017 Nov 14;138:184-187. Epub 2017 Sep 14.
    Postgraduate Program in Animal Science, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil; Veterinary Hospital, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil. Electronic address:
    Farmers from Paraiba state, Northeast Brazil, claim that Malachra fasciata causes cutaneous lesions in sheep. To test its toxicity the plant was harvested daily and fed ad libitum for 21 days to 3 sheep as the sole food source (# 1-3). An additional sheep (# 4) was maintained as a control. Read More

    Recalcitrant chronic leg ulcer: An indication for patch testing for hydrocolloid dressing.
    J Am Acad Dermatol 2017 10;77(4):e97-e98
    Department of Dermatology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; Department of Dermatology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

    Mucocutaneous inflammation in the Ikaros Family Zinc Finger 1-keratin 5-specific transgenic mice.
    Allergy 2017 Sep 15. Epub 2017 Sep 15.
    Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
    Background: Our genomewide association study documented an association between cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (CM-SJS/TEN) and Ikaros Family Zinc Finger 1 (IKZF1). Few studies examined biological and pathological functions of IKZF1 in mucosal immunity. We hypothesized that IKZF1 contributes to the mucocutaneous inflammation. Read More

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