38,233 results match your criteria Dermatitis Contact


A preliminary study of an alternative method for evaluating skin sensitizing potential of chemicals.

Int J Cosmet Sci 2019 Apr 16. Epub 2019 Apr 16.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.

The skin, being a barrier between the human body and the environment, is exposed to a series of exogenous chemicals and physical factors. Allergic contact dermatitis (ACD) is one of the most common inflammatory skin diseases that occurs in the general population with a prevalence of 20% [1]. The inflammatory condition is induced by a single or multiple exposure to chemical substances, called haptens, which activate the innate immunity (irritative contact dermatitis) or both innate and acquired immunity (allergic contact dermatitis) [2]. Read More

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http://dx.doi.org/10.1111/ics.12530DOI Listing

Repeat patch testing in a patient with allergic contact dermatitis improved on dupilumab.

JAAD Case Rep 2019 Apr 3;5(4):336-338. Epub 2019 Apr 3.

Department of Dermatology, Stanford University School of Medicine, Redwood City, California.

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https://linkinghub.elsevier.com/retrieve/pii/S23525126193003
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http://dx.doi.org/10.1016/j.jdcr.2019.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447730PMC
April 2019
7 Reads

Patch Testing in Allergic Contact Dermatitis over the Lower Extremities.

Indian J Dermatol 2019 Mar-Apr;64(2):164

Department of Dermatology, Venereology and Leprology, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Background: There is an increased incidence of allergic contact dermatitis (ACD) over the lower extremities due to over-the-counter topical preparations, occupational risk, and usage of several chemicals in the manufacture of designer footwear.

Aims And Objectives: The aim of the study was to identify the common allergens and polysensitization pattern involved in ACD over the lower extremities.

Materials And Methods: It is a cross-sectional study, wherein a total of 80 patients were recruited over a period of 18 months. Read More

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http://www.e-ijd.org/text.asp?2019/64/2/164/254171
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http://dx.doi.org/10.4103/ijd.IJD_759_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440194PMC
April 2019
2 Reads

Acetylation Phenotype Variation in Patients with Allergic Contact Dermatitis.

Indian J Dermatol 2019 Mar-Apr;64(2):164

Department of Dermatology, Al-Kadhimiya Teaching Hospital, Baghdad, Iraq.

Background: Studies have been done on acetylation phenotype in different diseases but not with allergic contact dermatitis (ACD).

Patients And Methods: Thirty-five ACD patients and 67 healthy volunteers were enrolled in the study. After an overnight fast, each participant received a single oral dose of 100 mg of dapsone. Read More

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http://www.e-ijd.org/text.asp?2019/64/2/164/254166
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http://dx.doi.org/10.4103/ijd.IJD_58_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440188PMC
April 2019
1 Read

Biophysical Measurements and Ultrasonographic Findings in Chronic Dermatitis in Comparison with Uninvolved Skin.

Indian J Dermatol 2019 Mar-Apr;64(2):90-96

Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.

Background: Nowadays noninvasive techniques are performed to evaluate the biophysical properties of skin .

Aims: The aim of this study was to evaluate the biophysical and ultrasonographic properties of skin in chronic contact or atopic dermatitis to provide better insight into pathogenesis, diagnosis, and treatment response.

Materials And Methods: The stratum corneum hydration, transepidermal water loss (TEWL), pH, erythema, melanin, sebum, friction, temperature, elasticity parameters (R0, R2, and R5), the thickness and echo-density of epidermis, dermis, and subepidermal low-echogenic band (SLEB) were measured on lesional, perilesional, and symmetrical skin of 22 chronic dermatitis patients. Read More

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http://dx.doi.org/10.4103/ijd.IJD_464_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440184PMC
April 2019
3 Reads

CCL2/CCR2 signaling elicits itch- and pain-like behavior in a murine model of allergic contact dermatitis.

Brain Behav Immun 2019 Apr 11. Epub 2019 Apr 11.

Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address:

Spontaneous itch and pain are the most common symptoms in various skin diseases, including allergic contact dermatitis (ACD). The chemokine (C-C motif) ligand 2 (CCL2, also referred to as monocyte chemoattractant protein 1 (MCP-1))and its receptor CCR2 are involved in the pathophysiology of ACD, but little is known of the role of CCL2/CCR2 for the itch- and pain-behaviors accompanying the murine model of this disorder, termed contact hypersensitivity (CHS). C57BL/6 mice previously sensitized to the hapten, squaric acid dibutyl ester, applied to the abdomen were subsequently challenged twice with the hapten delivered to either the cheek or to the hairy skin of the hind paw resulting in CHS at that site. Read More

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http://dx.doi.org/10.1016/j.bbi.2019.04.026DOI Listing
April 2019
2 Reads

An overview of herbal alternatives in androgenetic alopecia.

J Cosmet Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Dr. Bhanuben, Nanavati College of Pharmacy, Mumbai, India.

The second most common alopecia-Androgenetic alopecia (AGA)-occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53 minutes as compared to 35 minutes of testosterone. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.12930
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http://dx.doi.org/10.1111/jocd.12930DOI Listing
April 2019
2 Reads

Changing Trends of Contact Allergens in Thailand: A 12-Year Retrospective Study.

Contact Dermatitis 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand.

Background: Contact allergen prevalences often change. Continual surveillance is necessary to detect trends in sensitisation rates and emerging allergens.

Objective: To identify the prevalence of, and trends in, the positive reactions of each allergen in the baseline series during a 12-year period in Thailand. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13289
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http://dx.doi.org/10.1111/cod.13289DOI Listing
April 2019
2 Reads

Systemic allergic dermatitis after patch testing with dibucaine and topical corticosteroids.

Contact Dermatitis 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

Systemic allergic dermatitis arises if an individual sensitised via the skin is exposed to the same allergen or a cross reacting allergen by a different route . It is rarely elicited by cutaneous contact with an allergen , although transepidermal rechallenge has been reported . We report a case of systemic allergic dermatitis caused by patch testing. Read More

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http://dx.doi.org/10.1111/cod.13290DOI Listing
April 2019
1 Read

Dermatologic manifestations associated with electronic cigarette use.

J Am Acad Dermatol 2019 Apr 6. Epub 2019 Apr 6.

Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA. Electronic address:

Background: Electronic cigarette use continues rise, yet there are no reviews summarizing dermatologic manifestations associated with electronic cigarettes in the literature.

Objective: To review the literature regarding cutaneous manifestations associated with electronic cigarette use and increase awareness of side effects associated with this rapidly developing public health epidemic.

Methods: PubMed database was searched for related literature. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.088DOI Listing

Sensitization potential and potency of terpene hydroperoxides in the COCAT method.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Department of Environmental Toxicology, Trier University, Trier, Germany.

Background: Positive patch tests to mixtures of oxidized terpenes containing allergenic hydroperoxides are frequently reported. However, human sensitization data for these hydroperoxides are not available.

Objectives: To analyze and evaluate human sensitization potential and potency of hydroperoxides in vitro using human cells. Read More

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http://dx.doi.org/10.1111/cod.13286DOI Listing

Occupational Allergic Contact Dermatitis in Thai Spa Therapists.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Institute of Dermatology, Bangkok, Thailand.

Occupational allergic contact dermatitis (ACD) in spa therapists is common and can result in sick leave, change in occupation and impaired quality of life.(1) Spa products frequently contain fragrance chemicals which are added to obtain the desired aroma.(2) Whilst it is recognized that sensitization to fragrance chemicals can occur in aromatherapists. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13288
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http://dx.doi.org/10.1111/cod.13288DOI Listing
April 2019
5 Reads

Airborne allergic contact dermatitis caused by Machaerium scleroxylon: confirmation by in vivo and in vitro tests.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Section of Clinical, Allergological and Venereological Dermatology, Department of Medicine, University of Perugia, Italy.

Airborne agents can cause several skin reactions in occupational and less frequently in non-occupational settings, due to their strong irritant and/or sensitizing properties (1). Airborne allergic contact dermatitis is frequently caused by woods (2), above all tropical and subtropical woods containing many strong contact allergens, such as quinones (3). A case of airborne allergic contact dermatitis caused by Machaerium (M. Read More

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http://dx.doi.org/10.1111/cod.13287DOI Listing
April 2019
10 Reads

Evaluation of the Impact of 2 Disposable Diapers in the "Natural" Diaper Category on Diapered Skin Condition.

Clin Pediatr (Phila) 2019 Apr 9:9922819841136. Epub 2019 Apr 9.

1 The Procter & Gamble Company, Cincinnati, OH, USA.

The demand for natural infant care products, including diapers, has increased. However, few disposable diapers have been able to provide the performance caregivers desire while also incorporating ingredients consistent with the "natural" category. In an examiner-blinded clinical study, the performance of a new cotton-enhanced diaper with high-performance materials was compared with an existing natural diaper offering. Read More

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http://journals.sagepub.com/doi/10.1177/0009922819841136
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http://dx.doi.org/10.1177/0009922819841136DOI Listing
April 2019
7 Reads

African blackwood (Dalbergia melanoxylon) induced occupational allergic contact dermatitis in a professional piccolo flautist.

Contact Dermatitis 2019 Apr 7. Epub 2019 Apr 7.

Department of Dermatology and Allergy Unit, Turku University Hospital and University of Turku, Turku, Finland.

African blackwood (Dalbergia melanoxylon) also known as mpingo or grenadilla is a small dry climate African tree with grey bark and very dense red to black core wood. It is part of the genus Dalbergia and is distinct from ebony that involves many different species in the genus Diospyros. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13285DOI Listing
April 2019
1 Read

Molecular docking predictions of fragrance binding to HLA molecules.

Contact Dermatitis 2019 Apr 7. Epub 2019 Apr 7.

Division of Cosmetics, Office of Cosmetics and Colors, Maryland.

Background: Over 4000 small chemicals have been identified as allergens capable of inducing skin sensitization. Many sensitizers are hypothesized to act as haptens producing novel antigens which can be presented to T-cells by human leukocyte antigens (HLA). Recent studies suggest that some chemical allergens use hapten-independent mechanisms. Read More

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http://dx.doi.org/10.1111/cod.13283DOI Listing
April 2019
3 Reads

Contact granulomatous hypersensitivity to indium in a patient with orofacial granulomatosis.

Contact Dermatitis 2019 Apr 7. Epub 2019 Apr 7.

Division of Dermatology, Tokushima Red Cross Hospital, Tokushima, Japan.

Indium-induced allergic granulomas have never been reported to date. Herein, we describe a case of orofacial granulomatosis (OFG), where sarcoidal-type granulomas developed at a patch test site of indium chloride. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13284DOI Listing
April 2019
1 Read

Localised bullous pemphigoid overlying knee arthroplasty: a diagnostic challenge.

BMJ Case Rep 2019 Apr 5;12(4). Epub 2019 Apr 5.

Department of Surgery, Arrowe Park Hospital, Wirral, UK.

An elderly Caucasian woman developed bullous pemphigoid (BP) overlying the site of total knee arthroplasty for osteoarthritis 2 days after surgery. The clinical findings were consistent with blistering due to soft tissue swelling, bullous impetigo or allergic contact dermatitis. The blistering spread over weeks to months down the ipsilateral leg and then to the other leg and hips. Read More

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http://dx.doi.org/10.1136/bcr-2018-227440DOI Listing
April 2019
5 Reads

Allergic contact dermatitis in patients with atopic dermatitis: A retrospective study.

J Allergy Clin Immunol Pract 2019 Apr 5. Epub 2019 Apr 5.

Department of Health Sciences, University of Catanzaro "Magna Graecia," Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.jaip.2019.03.045DOI Listing
April 2019
2 Reads

[Ocular symptoms associated with dupilumab in atopic dermatitis].

Ned Tijdschr Geneeskd 2019 Mar 21;163. Epub 2019 Mar 21.

UMC Groningen, afd. Dermatologie.

Background: Dupilumab, the first registered biological for the treatment of atopic dermatitis, frequently causes adverse ocular events. These often take the form of mild conjunctivitis or blepharoconjunctivitis, however, more serious adverse ocular events have also been reported, including limbal stem cell insufficiency.

Case Description: A 56-year-old man was treated with dupilumab for severe atopic dermatitis. Read More

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March 2019
1 Read

The neglected element of hand hygiene - significance of hand drying, efficiency of different methods and clinical implication: A review.

J Infect Prev 2019 Mar 5;20(2):66-74. Epub 2018 Dec 5.

College of Human and Health Sciences, Room 111, Swansea University, Singleton Park, Swansea, UK.

Hand hygiene is a fundamental strategy for controlling the spread of infection. Careful hand drying is integral to the process of hand hygiene, which aims to optimise the removal of potentially pathogenic microorganisms. Ineffective hand drying results in wet hands that are an infection risk increasing the potential for cross-infection, occupational contact dermatitis for healthcare practitioners, harm to patients and environmental contamination. Read More

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http://dx.doi.org/10.1177/1757177418815549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437338PMC
March 2019
1 Read

Late cutaneous reaction after gold patch testing with features of Langerhans cell histiocytosis.

Contact Dermatitis 2019 Apr 2. Epub 2019 Apr 2.

Department of Dermatology, University Hospital Complex, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1111/cod.13281DOI Listing
April 2019
3 Reads

Medical Encounters During the United States Army Special Forces Assessment and Selection Course.

Mil Med 2019 Apr 3. Epub 2019 Apr 3.

Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760.

Introduction: The Special Forces Assessment and Selection (SFAS) is an extremely physically and mentally demanding 19- to 20-day course designed to determine whether Soldiers are qualified to enter the Special Forces Qualification Course. As a first step to understand medical problems during SFAS, this study examined injuries, illnesses, and activities associated with injuries during the course.

Materials And Methods: Medical events during the SFAS course were compiled from Sick Call Trackers (a log of medical encounters maintained by medical personnel in the field) and Chronology of Medical Care (Standard Form 600). Read More

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http://dx.doi.org/10.1093/milmed/usz056DOI Listing
April 2019
8 Reads

Impact of Allergic Contact Dermatitis on the Quality of Life and Work Productivity.

Dermatol Res Pract 2019 3;2019:3797536. Epub 2019 Mar 3.

Occupational Medicine Department, Teaching Hospital Farhat Hached Sousse, Tunisia.

Background: Allergic contact dermatitis (ACD) is a common chronic skin disease that generates considerable public-health and socioeconomic costs. This disease affects the quality of life and the occupational activity of patients.

Aims: To assess the quality of life (QOL) of patients with ACD and study the impact of this disease on their work productivity. Read More

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http://dx.doi.org/10.1155/2019/3797536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421021PMC
March 2019
1 Read

Dermatitis artefacta: self-inflicted genital injury.

Int Med Case Rep J 2019 18;12:71-73. Epub 2019 Mar 18.

Department of Dermatology and Venereology, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991, Moscow, Russia,

Background: The term dermatitis artefacta (factitious dermatitis, pathomimia) is reserved for the most severe variant of factitious physical disorder and is characterized by exaggerated lying (pseudologia fantastica), sociopathy, geographic wandering (peregrinating) from hospital to hospital, and seeking to be in the patient role.

Objective: This report aims to give attention to the importance of accurate and detailed history, and conducting an appropriate physical examination in patients with life-threatening diseases when the underlying cause is not apparent. The diagnosis of dermatitis artefacta must always be upheld. Read More

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http://dx.doi.org/10.2147/IMCRJ.S192522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429999PMC
March 2019
4 Reads

Moisture-associated skin damage: use of a skin protectant containing manuka honey.

Authors:
Sue Woodward

Br J Nurs 2019 Mar;28(6):329-335

Senior Lecturer, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London.

The skin is the largest organ in the body, providing an effective barrier against excessive fluid loss and invasion from bacteria, but the barrier function of the skin can be lost when it is damaged by prolonged contact with moisture. Moisture-associated skin damage can be caused by prolonged exposure to perspiration, urine or faeces, wound exudate or stomal output. Prevention and treatment of moisture-associated skin damage involves application of skin protectants, but there is a wide range of these products available to nursing staff, and clinical decision making is hampered by a lack of robust comparative evidence. Read More

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http://dx.doi.org/10.12968/bjon.2019.28.6.329DOI Listing
March 2019
2 Reads

Another source of allergic contact dermatitis to isothiazolinones in children-urgent call for regulation.

J Eur Acad Dermatol Venereol 2019 Mar 29. Epub 2019 Mar 29.

Dermatology Department, Coimbra University Hospital, Coimbra, Portugal.

Allergic contact dermatitis (ACD) from isothiazolinones is frequent and following an epidemic sensitization their use in leave-on products in Europe was forbidden and restricted that in rinse-off cosmetics, with a consequent decrease in the frequency of new cases in Europe, but still not evident in Portugal. Although more common in adults, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are also prevalent paediatric contact sensitizers. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/jdv.15602DOI Listing
March 2019
1 Read

Evaluation of dry eye disase and meibomian gland dysfunction with meibography in seborrheic dermatitis.

Cont Lens Anterior Eye 2019 Mar 25. Epub 2019 Mar 25.

Aksaray Training and Research Hospital, Ophthalmology Department, Aksaray, Turkey.

Purpose: To evaluate the dry eye disase and meibomian gland dysfunction with meibography of Seborrheic Dermatit patients.

Methods: A hundred-ten of 50 patients with Seborrheic Dermatitis (group 1) and 100 eyes of 50 healthy individuals (group 2) were enrolled in this prospective study. All subjects were performed a comprehensive ophthalmic examination including lid margin alterations and meibomian gland obstruction assessment, Ocular Surface Disease Index assessment, tear film break-up time test, corneal and conjunctival fluorescein staining assessment, Schirmer test. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.005DOI Listing
March 2019
1 Read

Post-operative purpuric contact dermatitis : think about antiseptics.

Contact Dermatitis 2019 Mar 28. Epub 2019 Mar 28.

Department of Dermatology, Saint Eloi Hospital, University Hospital Center of Montpellier, France.

A 28-year-old female patient underwent surgery for buttock synechias as a result of previous surgery for pilonidal sinus. She was positioned prone during the reconstructive surgery. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13277DOI Listing
March 2019
4 Reads

Contact allergy to Tinuvin 770, a hindered amine light stabilizer in sandals contributing to hyperkeratotic foot dermatitis.

Contact Dermatitis 2019 Mar 28. Epub 2019 Mar 28.

National Institute of Technology and Evaluation (NITE) - Biological Resource Center, Shibuya-ku, Tokyo, Japan.

Tinuvin 770 (bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate; BTMPS) is a hindered amine light stabilizer (HALS) used to prevent deterioration and discoloration of polymer compounds. We herein report the first case of allergic contact dermatitis caused by Tinuvin 770. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13279DOI Listing
March 2019
2 Reads

Th9 Cells in Allergic Disease.

Curr Allergy Asthma Rep 2019 Mar 26;19(5):29. Epub 2019 Mar 26.

Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, 12120, Thailand.

Purposes Of Review: Th9 cells are recognized as a novel subset of effector T helper cells that preferentially produce IL-9. Here, we provide a current update on the reports related to the function of Th9 cells in allergic inflammatory diseases.

Recent Findings: The effector Th9 cells differentiating from naïve T helper cells have recently been identified. Read More

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http://dx.doi.org/10.1007/s11882-019-0860-8DOI Listing
March 2019
3 Reads

Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis.

Evid Based Complement Alternat Med 2019 24;2019:8612561. Epub 2019 Feb 24.

Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China.

Background: Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. Read More

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http://dx.doi.org/10.1155/2019/8612561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409027PMC
February 2019
2 Reads

Allergic contact dermatitis caused by oxidized linalool in a deodorant.

Contact Dermatitis 2019 Mar 26. Epub 2019 Mar 26.

Stockholm University, Department of Environmental Science and Analytical Chemistry, Stockholm, Sweden.

Linalool hydroperoxides (LinOOHs) frequently cause fragrance contact allergy (1-3). However, to our knowledge, there is only one case of dermatitis reported related to a scented product containing LinOOHs confirmed with chemical analysis (4). This article is protected by copyright. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13276
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http://dx.doi.org/10.1111/cod.13276DOI Listing
March 2019
5 Reads

RARE BURN CASES TREATED TRADITIONALLY: FOLK MEDICINE: REVIEW OF 8 CASES.

J Burn Care Res 2019 Mar 25. Epub 2019 Mar 25.

University of Health Sciences Gazi Yaşargil Training and Research Hospital, Diyarbakır, Anesthesiology.

The most common burn injuries in the Turkish population are scalding (traditional Turkish tea, hot milk, liquid food, etc.), electricity and chemical agents. However, many plants that are used as herbal medicine can also cause adverse effects such as allergic contact dermatitis and burns. Read More

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http://dx.doi.org/10.1093/jbcr/irz048DOI Listing
March 2019
2 Reads

Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.

Sci Rep 2019 Mar 25;9(1):5085. Epub 2019 Mar 25.

Department of Environmental Medicine, University of Rochester Medical Center, New York, USA.

Amorphous silicon dioxide nanoparticles (SiNPs) are ubiquitous, and they are currently found in cosmetics, drugs, and foods. Biomedical research is also focused on using these nanoparticles as drug delivery and bio-sensing platforms. Due to the high potential for skin exposure to SiNPs, research into the effect of topical exposure on both healthy and inflammatory skin models is warranted. Read More

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http://dx.doi.org/10.1038/s41598-019-41493-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434075PMC
March 2019
1 Read

Airborne contact dermatitis apparently acquired when using pericarp juice from Indian marking nut as a home remedy to treat patchy hair loss.

Contact Dermatitis 2019 Mar 25. Epub 2019 Mar 25.

Dermatology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Indian marking nut is the fruit of Semecarpus anacardium L.f., which, after suitable preparation, is highly valued in Indian traditional systems of medicine, especially Ayurveda. Read More

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http://dx.doi.org/10.1111/cod.13275DOI Listing

Fragrance inhalation and adverse health effects: The question of causation.

Regul Toxicol Pharmacol 2019 Jun 21;104:151-156. Epub 2019 Mar 21.

Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.

The toxicology of fragrance materials is largely well understood. Although most are benign, a minority have the potential to cause adverse health effects, notably allergic contact dermatitis resulting from skin sensitization. As a consequence, industry guidelines have banned certain materials and strictly limited the use of others. Read More

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http://dx.doi.org/10.1016/j.yrtph.2019.03.011DOI Listing
June 2019
1 Read

Allergic contact dermatitis caused by benzisothiazolinone in a continuous positive airway pressure mask liquid soap.

Contact Dermatitis 2019 Mar 23. Epub 2019 Mar 23.

Occupational Dermatology Research and Education Centre, The Skin and Cancer Foundation Inc., Carlton, Victoria, Australia.

As important allergens methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) are removed from products, their replacements, including other isothiazolinones, may emerge as significant allergens. We report a case of allergic contact dermatitis of the hands to benzisothiazolinone (BIT) after exposure to a liquid soap and a dishwashing concentrate. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13273DOI Listing
March 2019
2 Reads

Response to: Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study.

Contact Dermatitis 2019 Mar 23. Epub 2019 Mar 23.

Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1111/cod.13272DOI Listing

Patch test results obtained with the European baseline series at a diagnostics centre in Abuja, Nigeria.

Contact Dermatitis 2019 Mar 23. Epub 2019 Mar 23.

Paediatric Department, Medicaid Radio-diagnostics, Abuja, Nigeria.

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http://dx.doi.org/10.1111/cod.13274DOI Listing
March 2019
3 Reads

Cosmetics for neonates and infants: haptens in products' composition.

Clin Transl Allergy 2019 8;9:15. Epub 2019 Mar 8.

Department of Pediatric Pneumology and Allergy, The Medical University of Warsaw, Żwirki i Wigury 63A, 02-091 Warsaw, Poland.

Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in cosmetics designed for children younger than 1 year. Read More

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http://dx.doi.org/10.1186/s13601-019-0257-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407239PMC
March 2019
1 Read

Don't forget the sponge.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Brigham and Women's Hospital, Chestnut Hill, Massachusetts.

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http://dx.doi.org/10.1111/cod.13270DOI Listing
March 2019
4 Reads

Allergic contact dermatitis caused by synthetic rubber gloves in healthcare workers: Sensitization to 1,3-diphenylguanidine is common.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Cliniques universitaires Saint-Luc, Brussels, Belgium and IREC (Institut de Recherche Experimentale et Clinique) Pôle Pneumologie, ORL, Dermatologie, Université Catholique de Louvain, Brussels, Belgium.

Background: The frequency of allergic contact dermatitis has significantly increased in healthcare workers since the transition from latex to synthetic rubber gloves, with 1,3-diphenylguanidine being identified as the most frequently implicated allergen.

Objectives: To highlight the role of 1,3-diphenylguanidine as the culprit allergen in contact allergies to synthetic rubber gloves, to propose recommendations for patch testing, and to discuss alternatives for sensitized subjects.

Materials And Methods: Patch test data from healthcare workers who developed hand dermatitis after wearing rubber gloves and who reacted positively to glove samples and rubber additives were collected from September 2010 to December 2017 in a Belgian hospital. Read More

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http://dx.doi.org/10.1111/cod.13269DOI Listing
March 2019
3 Reads

Allergic contact dermatitis to phenylbenzimidazole sulfonic acid included in a sunscreen.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Hospital Universitario del Henares, Coslada (Madrid), Spain.

Adverse reactions to sunscreens include allergic, irritant, phototoxic and photoallergic contact dermatitis (1). Allergic and photoallergic contact dermatitis to sunscreen may be caused by chemical ultraviolet (UV) absorbers, preservatives, perfumes, and other constituents. Photoallergic contact dermatitis reaction to UV absorbers is not common, and more frequent than allergic contact dermatitis. Read More

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http://dx.doi.org/10.1111/cod.13271DOI Listing
March 2019
2 Reads

Contact dermatitis due to transdermal therapeutic systems: a clinical update.

Acta Biomed 2018 Oct 26;90(1):5-10. Epub 2018 Oct 26.

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Italy.

Transdermal therapeutic systems (TTS) have become a popular method of drug delivery because they allow drugs to be delivered in a rate-controlled manner, avoiding first-pass metabolism and the fluctuating plasma concentrations encountered with oral medications. Unfortunately, TTS may provoke adverse skin reactions as irritating contact dermatitis and allergic contact dermatitis: TTS seem to be ideally suited to produce sensitization because they cause occlusion, irritation, due to the repeated placement of the allergen in the same skin location. Since TTS consist of an adhesive, an active pharmaceutical drug and enhancing agents, sensitization may develop owing to one of these three agents. Read More

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http://dx.doi.org/10.23750/abm.v90i1.6563DOI Listing
October 2018
2 Reads

Evaluation of positive patch test reactions using optical coherence tomography: A pilot study.

Skin Res Technol 2019 Mar 19. Epub 2019 Mar 19.

Dr.Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Introduction: Patch testing is the gold standard for evaluating allergic contact dermatitis (ACD), yet current interpretation methods are limited by their subjectivity and possible variability between observers. Optical coherence tomography (OCT) imaging enables noninvasive in vivo skin visualization and holds promise as an objective method of patch test interpretation.

Objective: To evaluate the micromorphological changes of patch test reactions and identify objective, quantitative OCT markers that correlate with clinically graded patch test reactions. Read More

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http://dx.doi.org/10.1111/srt.12695DOI Listing
March 2019
1 Read

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.

Eur J Epidemiol 2019 Mar 18;34(3):279-300. Epub 2019 Mar 18.

Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. Read More

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http://dx.doi.org/10.1007/s10654-019-00502-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447695PMC
March 2019
6 Reads
5.339 Impact Factor