117,526 results match your criteria Dermatitis : contact atopic occupational drug : official journal of the American Contact Dermatitis Society North American Contact Dermatitis Group[Journal]


Adverse Events from Emollient Use in Eczema: A Restricted Review of Published Data.

Dermatol Ther (Heidelb) 2019 Feb 15. Epub 2019 Feb 15.

Population Health Sciences, University of Bristol, Bristol, UK.

Atopic dermatitis/eczema is a chronic inflammatory skin condition, and emollients are the first-line treatment. Despite their widespread use, there is uncertainty about the frequency and type of adverse events associated with different emollients. We conducted a restricted review of published data on adverse events associated with emollient use in eczema. Read More

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http://dx.doi.org/10.1007/s13555-019-0284-3DOI Listing
February 2019

A Summary of 2018 and What Lies Ahead for Dermatology and Therapy in 2019.

Dermatol Ther (Heidelb) 2019 Feb 15. Epub 2019 Feb 15.

Dermatology Centre, Salford Royal NHS Foundation Trust, Manchester NIHR BRC, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s13555-019-0283-4DOI Listing
February 2019

Alkali-soluble pectin suppresses IgE production in human myeloma cell line in vitro.

Cytotechnology 2019 Feb 15. Epub 2019 Feb 15.

Department of Creative Engineering, National Institute of Technology, Kitakyushu College, 5-20-1 Shii, Kokuraminami-ku, Kitakyushu, Fukuoka, 802-0985, Japan.

We found that strawberry (Fragaria x ananassa) extract has an IgE production suppressive activity and its oral administration improved skin manifestation in atopic dermatitis model mice. In present study, we identified an active substance using the IgE-producing human myeloma cell line U266. Gel filtration experiment indicated that the IgE suppressor was more than 6 kDa in molecular size. Read More

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http://dx.doi.org/10.1007/s10616-019-00306-5DOI Listing
February 2019

Determinants of disease severity among patients with atopic dermatitis: association with components of the atopic march.

Arch Dermatol Res 2019 Feb 15. Epub 2019 Feb 15.

Department of Dermato-venereology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

We aimed to explore the association of key clinical characteristics with disease severity in atopic dermatitis (AD) and its relation to components of the atopic march in a large hospital cohort. Outpatients with AD referred to the Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark, between January 2012 and December 2017, were compared based on disease severity (SCORAD); mild (< 25), moderate (25-50) and severe (> 50). A total of 470 AD patients were included: 122 small children (< 4 years of age), 103 children/adolescents (age 4-15 years) and 245 adults (> 15 years of age). Read More

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http://dx.doi.org/10.1007/s00403-019-01895-zDOI Listing
February 2019

High dietary fat intake induces a microbiota signature that promotes food allergy.

J Allergy Clin Immunol 2019 Feb 12. Epub 2019 Feb 12.

Institute of Pathology, Department of Experimental Pathology, University of Bern, Bern, Switzerland. Electronic address:

Background: Diet-induced obesity and food allergies rise in tandem, but a potential cause-and-effect relationship between these diseases of affluence remains to be tested.

Objective: To test the role of high dietary fat intake, diet-induced obesity and associated changes in gut microbial community structure on food allergy pathogenesis.

Methods: Mice were fed a high fat diet (HFD) for 12 weeks prior to food allergen sensitization on an atopic dermatitis-like skin lesion followed by intra-gastric allergen challenge to induce experimental food allergy. Read More

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http://dx.doi.org/10.1016/j.jaci.2019.01.043DOI Listing
February 2019

Towards personalized treatment in atopic dermatitis.

Expert Opin Biol Ther 2019 Feb 15. Epub 2019 Feb 15.

a National Expertise Center for Atopic Dermatitis. Department of Dermatology and Allergology , University Medical Center Utrecht , The Netherlands .

Introduction: For many years, oral immunosuppressive drugs such as cyclosporine A, azathioprine, mycophenolic acid and methotrexate were the only treatment options, in addition to topical treatment, in patients with severe atopic dermatitis (AD). Dupilumab, a monoclonal antibody targeting the IL-4 receptor alpha, is the first antibody-based treatment commercially available for the treatment of AD. In the near future, more antibody-based treatments and small molecules will become available in the treatment of severe AD. Read More

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http://dx.doi.org/10.1080/14712598.2019.1583204DOI Listing
February 2019

Food Protein-Induced Enterocolitis Syndrome in South Tyrol 2012-2016: a population based study.

J Eur Acad Dermatol Venereol 2019 Feb 14. Epub 2019 Feb 14.

College of Health-Care Professions Claudiana, Bolzano/Bozen.

Food protein-induced enterocolitis syndrome (FPIES) is a rare non-IgE-mediated food allergy to protein mainly in cow milk (CM) that typically presents in early infancy. Projectile and repetitive vomiting are the main clinical symptoms after 1-4 hours of trigger food ingestion. Rapid recognition and installment of a specific diet are important to avoid serious complications in affected children (see figure 1). Read More

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http://dx.doi.org/10.1111/jdv.15510DOI Listing
February 2019

Validation of the dermatology-specific proxy instrument the Infants and Toddlers Dermatology Quality of Life.

J Eur Acad Dermatol Venereol 2019 Feb 14. Epub 2019 Feb 14.

Department of Pediatrics number 1, National Medical University, Kiev, Ukraine.

Background: The first dermatology-specific proxy health related quality of life (HRQoL) instrument for children 0-4 years old with skin diseases, the Infants and Toddlers Dermatology Quality of Life (InToDermQoL), was recently developed. In order to avoid the problem of cross-cultural inequivalence focus groups work and pilot tests were organized simultaneously in all national centres of the project. The InToDermQoL showed good comprehensibility, clarity and acceptance. Read More

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http://dx.doi.org/10.1111/jdv.15496DOI Listing
February 2019

Papulopustular Dermatitis in X-Linked Chronic Granulomatous Disease.

Front Pediatr 2018 31;6:429. Epub 2019 Jan 31.

Division of Pediatric Allergy and Immunology, Department of Pediatrics, University of Rochester Medical Center, Golisano Children's Hospital, Rochester, NY, United States.

Here we describe two term male infants diagnosed with X-linked CGD who present, in addition to frequent infection, with a unique papulopustular skin rash. CGD is caused by a number of genetic defects that impair phagocyte function. This disease results in recurrent infections and granuloma formation. Read More

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http://dx.doi.org/10.3389/fped.2018.00429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365455PMC
January 2019

Health care worker sensitivity to chlorhexidine-based hand hygiene solutions: A cross-sectional survey.

Am J Infect Control 2019 Feb 11. Epub 2019 Feb 11.

School of Nursing and Midwifery, Deakin University, Geelong, Victoria, Australia; Centre for Quality and Patient Safety Research-Monash Health Partnership, School of Nursing and Midwifery, Deakin University, Burwood, Victoria, Australia. Electronic address:

Background: Health service hand hygiene programs have seen widespread use of chlorhexidine solutions. Reports of both immediate and delayed hypersensitivity to chlorhexidine are increasing among health care workers. This study examined the prevalence of self-reported symptoms of sensitivity to chlorhexidine solutions among health care workers. Read More

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http://dx.doi.org/10.1016/j.ajic.2019.01.006DOI Listing
February 2019

Self-report occupational-related contact dermatitis: prevalence and risk factors among healthcare workers in Gondar town, Northwest Ethiopia, 2018-a cross-sectional study.

Environ Health Prev Med 2019 Feb 14;24(1):11. Epub 2019 Feb 14.

Department of Environmental and Occupational Health and Safety, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.

Background: Occupational skin diseases are the second most common occupational diseases and are responsible for an estimated 25% of all lost work days. Occupational contact dermatitis (OCD) comprises 70-90% of all occupational skin diseases. In Ethiopia, information about the prevalence and factors which determine developments of contact dermatitis is not recognized. Read More

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http://dx.doi.org/10.1186/s12199-019-0765-0DOI Listing
February 2019

The Role of Probiotics in Preventing Allergic Disease.

Children (Basel) 2019 Feb 5;6(2). Epub 2019 Feb 5.

Department of Pediatrics, Section of Immunology, Allergy, Rheumatology, and Retrovirology, Texas Children's Hospital, Houston, TX 77030, USA.

The prevalence of allergic disorders has been increasing worldwide and significantly impacts the quality of life of the atopic individual. There has been an increased interest in the role of probiotics for the prevention and treatment of allergic disorders, given the recent evidence that atopy risk may be associated with a dysbiosis of the gut microbiome. Research in this area is ongoing with some studies showing possible benefits of probiotics, with seemingly little to no risk. Read More

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http://dx.doi.org/10.3390/children6020024DOI Listing
February 2019

Hand eczema among Dutch beekeepers - a cross-sectional study.

J Dtsch Dermatol Ges 2019 Feb;17(2):158-166

University of Groningen, University Medical Center Groningen, Department of Dermatology, The Netherlands.

Background And Objectives: Studies of beekeepers have mostly focused on contact allergy to propolis. The overall prevalence of hand eczema (HE) in beekeepers has not been studied. Our objectives were to gain insight into the prevalence of HE in the Dutch beekeeper population; to define the impact of beekeeping activities on HE and vice versa; and to determine associated factors. Read More

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http://dx.doi.org/10.1111/ddg.13754DOI Listing
February 2019

Acute generalized exanthematous pustulosis induced by iomeprol with cross-reactivity to other iodinated contrast agents and mild reaction after rechallenge with iopromide and oral corticosteroid premedication.

Contact Dermatitis 2019 Feb 14. Epub 2019 Feb 14.

Department of Dermatology, University of Tours, France.

Immediate hypersensitivity reactions to iodinated contrast media (ICM) are rare and occur within 1 hour after infusion, but also up to 7 days later. This article is protected by copyright. All rights reserved. Read More

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http://dx.doi.org/10.1111/cod.13242DOI Listing
February 2019
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Rituximab revisited: successful management of severe childhood atopic dermatitis.

Eur J Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Dermatology, Hospital de Santo António dos Capuchos.

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http://dx.doi.org/10.1684/ejd.2018.3476DOI Listing
February 2019

Differences in the Clinical and Laboratory Features of Imported Onchocerciasis in Endemic Individuals and Temporary Residents.

Am J Trop Med Hyg 2019 Feb 11. Epub 2019 Feb 11.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Many parasitic infections have different presenting features in endemic individuals (ENDs) and immunologically naive temporary residents (TRs). Temporary residents with loiasis often display acute symptoms and hypereosinophilia, in contrast to a parasite-induced subclinical state in chronically infected ENDs. Few studies have examined differences in ENDs and TRs infected with the related filarial parasite . Read More

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http://dx.doi.org/10.4269/ajtmh.18-0757DOI Listing
February 2019
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Reactions to Gudair® vaccination identified in sheep used for biomedical research.

Aust Vet J 2019 Feb 13. Epub 2019 Feb 13.

Ear Sciences Centre, School of Medicine, the University of Western Australia, Crawley, WA, Australia.

Case Report: We report Gudair® vaccination (against ovine Johne's disease, Mycobacterium avium subsp. paratuberculosis) site reactions in sheep used as a surgical model in biomedical research and discuss the actual and potential impact these lesions may have on surgical procedures, particularly in otology. Nine female Merino-cross sheep (Ovis aries) were enrolled in a project designed to investigate the healing capabilities of the malleus bone in the middle ear. Read More

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http://dx.doi.org/10.1111/avj.12788DOI Listing
February 2019

Systematic Analysis of Selective Bactericidal Activity of Fatty Acids against Staphylococcus aureus with Minimum Inhibitory Concentration and Minimum Bactericidal Concentration.

J Oleo Sci 2019 Feb 13. Epub 2019 Feb 13.

Department of Biochemical Engineering, Graduate School of Science and Engineering, Yamagata University.

Bacterial flora on the skin surface contains Staphylococcus aureus (S. aureus) and Staphylococcus epidermidis (S. epidermidis) which causes rough skin and atopic dermatitis and enhances innate immunity, respectively. Read More

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http://dx.doi.org/10.5650/jos.ess18220DOI Listing
February 2019

An epidemiological investigation of porcine circovirus 3 infection in cattle in Shandong province, China.

BMC Vet Res 2019 Feb 13;15(1):60. Epub 2019 Feb 13.

College of Animal Science and Technology, Guangxi University, Nanning, 530004, China.

Background: Porcine circovirus type 3 (PCV3) is a single-stranded, closed circular DNA virus, which causes porcine dermatitis and nephropathy syndrome (PDNS), multisystemic inflammation, and reproductive failure. The present study aimed to investigate the seroprevalence of PCV3 in cattle (Bos taurus) in Shandong province, China, and examine its genome diversity.

Results: PCR amplification and sequencing showed that 74 of 213 bovine samples (34. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-019-1793-0DOI Listing
February 2019
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Development of a gold nanoparticle-labeled sandwich format lateral flow immunoassay kit for the detection of tropical house dust mite Suidasia pontifica.

Protein Pept Lett 2019 Feb 12. Epub 2019 Feb 12.

The Graduate School, bCollege of Science, University of Santo Tomas, España Boulevard, Sampaloc 1015, Manila. Philippines.

The house dust mite Suidasia pontifica (Sp) is an important source of allergens in tropical regions that trigger IgE-mediated allergic reactions such as allergic asthma, atopic dermatitis and allergic rhinitis. Detection of Sp-specific proteins are important in the management and prevention of allergic diseases. The study aimed to provide a proof of concept for a gold nanoparticle-labeled sandwich format lateral flow immunoassay (LFIA) kit for the detection of Sp-specific proteins. Read More

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http://dx.doi.org/10.2174/0929866526666190212164751DOI Listing
February 2019
1 Read

Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine.

Vaccines (Basel) 2019 Feb 12;7(1). Epub 2019 Feb 12.

University of Dundee, Medical School, Department of Molecular and Clinical Medicine, Jacqui Woods Centre, Ninewells Hospital, Ninewells Drive, Dundee DD1 9SY, UK.

Background: The development of therapeutic vaccines requires thorough knowledge of potential hazards associated with long-term inactivation of self-proteins. Among potential targets, interleukin 13 (IL-13) merits consideration, as monoclonal antibodies disrupting IL-13 signaling are proving to be exceedingly effective in common conditions such as atopic dermatitis.

Objective: Given the mass publication of scientific data, an appraisal of safety aspects is challenging. Read More

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http://dx.doi.org/10.3390/vaccines7010020DOI Listing
February 2019

Use of Complementary and Alternative Therapies in Outpatients with Atopic Dermatitis from a Dermatological University Department.

Dermatology 2019 Feb 13:1-7. Epub 2019 Feb 13.

Department of Dermato-Venereology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

Background: Treatment of atopic dermatitis (AD) may be challenging, therefore some patients seek complementary and alternative medications (CAM). We determined prevalence and predictors for CAM use in a hospital cohort of AD patients.

Material And Methods: Between January 1, 2012, and December 31, 2017, AD patients referred to the dermatological outpatient clinic at Bispebjerg Hospital were included in the study. Read More

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https://www.karger.com/Article/FullText/496274
Publisher Site
http://dx.doi.org/10.1159/000496274DOI Listing
February 2019
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Allergic contact dermatitis caused by isobornyl acrylate when using the FreeStyle Libre.

J Diabetes Investig 2019 Feb 13. Epub 2019 Feb 13.

Department of Dermatology, Nihon University Hospital, Tokyo, Japan.

We present the case of an 8-year old girl with type 1 diabetes, who developed severe allergic contact dermatitis by using FreeStyle Libre. A patch test was performed by a piece of the adhesive part of the sensor of the FreeStyle Libre, and subsequently by using the potential contact allergens in the sensor, isobornyl acrylate (IBOA). She reacted positively to the adhesive part of the sensor, and also reacted positively to IBOA with three different concentrations, 0. Read More

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http://dx.doi.org/10.1111/jdi.13023DOI Listing
February 2019

Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide.

Br J Dermatol 2019 Feb 13. Epub 2019 Feb 13.

Regeneron Pharmaceuticals, Inc, Tarrytown, NY, U.S.A.

Background: Atopic dermatitis (AD) is a heterogeneous disease with a multifactorial aetiology and complex pathophysiology. This heterogeneity translates into different trajectories of disease progression with respect to severity, persistence, and risk of development of atopic comorbidities. Determining which possible disease trajectories or comorbidities any individual child might develop is challenging in clinical practice. Read More

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http://dx.doi.org/10.1111/bjd.17766DOI Listing
February 2019

Prevalence of vitamin D deficiency and its relationship with factors associated with recurrent wheezing.

J Bras Pneumol 2019 Feb 11;45(1):e20170431. Epub 2019 Feb 11.

. Departamento de Medicina e Enfermagem, Universidade Federal de Viçosa, Viçosa (MG) Brasil.

Objective: To determine the prevalence of vitamin D deficiency/insufficiency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing.

Methods: A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained interviewers to the legal guardians of the study participants. Data were obtained regarding general characteristics of recurrent wheezing; general sociodemographic, environmental, and biologic factors; and atopy-related factors. Read More

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http://dx.doi.org/10.1590/1806-3713/e20170431DOI Listing
February 2019

Pediatric warts: update on interventions.

Cutis 2019 Jan;103(1):26;27;28;29;30;E2;E3;E4

Departments of Dermatology and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Warts are superficial viral infections of the skin that are extremely common in children. The infection usually lasts more than 1 year and can be moderately contagious in specific settings; for instance, warts are particularly common and spread more easily in the setting of atopic dermatitis, a chronic, itchy pediatric skin condition caused by barrier and immune defects. Therapies for pediatric warts are characterized according to 6 major categories: destructive; immune stimulating; immune modulating, including normalization of epithelial growth; vascular destructive; irritant; and nitric oxide releasing. Read More

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January 2019

Pityriasis amiantacea following bone marrow transplant.

Cutis 2019 Jan;103(1):46-50

San Diego Family Dermatology, National City, California; Family Health Center of San Diego, California; Scripps Mercy Hospital Chula Vista, California; and the College of Osteopathic Medicine, Touro University California, Vallejo, USA.

Pityriasis amiantacea (PA) is a hair disorder characterized by matting of multiple hair shafts, typically occurring as an idiopathic condition. A 67-year-old woman with multiple myeloma who developed PA following a bone marrow transplant with melphalan conditioning is described.She noted initial changes in scalp hair regrowth 4 weeks posttransplant. Read More

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January 2019

Atopic dermatitis disease registry in Japanese adult patients with moderate to severe atopic dermatitis (ADDRESS-J): Baseline characteristics, treatment history and disease burden.

J Dermatol 2019 Feb 13. Epub 2019 Feb 13.

Sanofi K.K., Tokyo, Japan.

Moderate to severe atopic dermatitis (AD) has a high disease burden and a significant effect on quality of life. Observational studies are necessary to determine the patient disease burden and long-term disease control in the Japanese population. ADDRESS-J is a non-interventional, observational registry of adult Japanese patients with moderate to severe AD. Read More

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http://dx.doi.org/10.1111/1346-8138.14787DOI Listing
February 2019

Occupational acute generalized exanthematous pustulosis induced by disperse dyes in textile.

Contact Dermatitis 2019 Feb 12. Epub 2019 Feb 12.

Department of dermatology, Fattouma Bourguiba Hospital, Monastir, Tunisia.

Acute generalized exanthematous pustulosis (AGEP) is a severe eruption characterized by numerous non-follicular sterile pustules on an erythematous background. AGEP is mostly caused by systemic drugs mainly antibiotics. Others causes of AGEP, such as contact with mercury, spider bites and viral infection had been described. Read More

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http://dx.doi.org/10.1111/cod.13241DOI Listing
February 2019
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Acute Exacerbation of Fever Following Administration of Tropicamide and Phenylephrine Ophthalmic Solution: A Case Report.

Drug Saf Case Rep 2019 Feb 12;6(1). Epub 2019 Feb 12.

Juntendo University School of Medicine, Tokyo, Japan.

A 24-year-old woman with atopic dermatitis and persistent fever (axillary temperature of 37-38 °C for 6 months) received combination ophthalmic drops containing tropicamide and phenylephrine (Mydrin-P), which exacerbated her fever within 15 min after instillation. Her axillary fever reached 40.1 °C but resolved the following day. Read More

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http://dx.doi.org/10.1007/s40800-019-0096-5DOI Listing
February 2019

IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity.

Sci Rep 2019 Feb 12;9(1):1852. Epub 2019 Feb 12.

de Duve Institute, Université catholique de Louvain, Brussels, Belgium.

Para-Phenylenediamine (PPD) is an aromatic amine used in hair dyes and in temporary black henna tattoos, which is a frequent cause of allergic contact dermatitis (ACD). ACD is a skin inflammatory reaction characterized by modifications such as spongiosis, exocytosis and acanthosis. The aim of this study is to characterize the expression and the role of IL-20-related cytokines, including IL-19, IL-20, IL-22 and IL-24, in ACD. Read More

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http://dx.doi.org/10.1038/s41598-018-38156-4DOI Listing
February 2019

Fresh water snails as intermediate host of trematodes in Iran: A systematic.

Epidemiol Health 2019 Jan 7:e2019001. Epub 2019 Jan 7.

Associate Professor, Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,, Sari, Iran.

Objectives: Freshwater snails, as first intermediate hosts of trematodes, can cause health hazards in animals and humans. Recently, WHO has included Iran among six countries known to have a serious problem with fascioliasis. In addition, Cercarial dermatitis is a job-related disease that is seen often in paddy workers and swimmers of Iran particularly in the Mazandaran province. Read More

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http://dx.doi.org/10.4178/epih.e2019001DOI Listing
January 2019

Inter-observer agreement between two observers for bovine digital dermatitis identification in New Zealand using digital photographs.

Authors:
D A Yang R Laven

N Z Vet J 2019 Feb 12:1-11. Epub 2019 Feb 12.

a School of Veterinary Science , Massey University , Palmerston North 4474 , New Zealand.

Aims: To assess the inter-observer agreement for detecting bovine digital dermatitis (BDD) lesions in digital colour photographs of the hind feet of cows, which had been taken while the animals were standing to be milked, between two trained observers.

Methods: Thirty-six photographs were selected from a total of 184 photographs held by the first author (R1), who had classified them as negative (n = 11) or positive (n = 25) for BDD. They were delivered to a technician (R2) who had previously visually inspected cattle for BDD lesions, and who then recorded the photographs as being either BDD-positive or BDD-negative. Read More

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http://dx.doi.org/10.1080/00480169.2019.1582369DOI Listing
February 2019

Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients.

Am J Clin Nutr 2019 Feb 9. Epub 2019 Feb 9.

Division of Radiation Oncology, Department of Radiation Oncology.

Background: Glutamine is the primary fuel for the gastrointestinal epithelium and maintains the mucosal structure. Oncologists frequently encounter oral mucositis, which can cause unplanned breaks in radiotherapy (RT).

Objectives: The aim of this study was to explore the association between oral glutamine and acute toxicities in patients with head and neck cancer undergoing RT. Read More

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http://dx.doi.org/10.1093/ajcn/nqy329DOI Listing
February 2019
1 Read

Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T-helper 2-driven proinflammatory responses in a mouse model of allergic dermatitis.

J Appl Toxicol 2019 Feb 12. Epub 2019 Feb 12.

Toxicology Division, Institute of Environmental Toxicology, 4321, Uchimoriya-machi, Joso-shi, Ibaraki, 303-0043, Japan.

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that binds to various environmental chemicals and contributes to numerous toxicological effects. However, the direct effects of AhR on the development of allergic diseases are not fully understood. The main aim of this study was to elucidate the action of AhR in the development of cutaneous allergies. Read More

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http://dx.doi.org/10.1002/jat.3782DOI Listing
February 2019

Anti‑inflammatory effects of Dendropanax morbifera in lipopolysaccharide‑stimulated RAW264.7 macrophages and in an animal model of atopic dermatitis.

Mol Med Rep 2019 Jan 22. Epub 2019 Jan 22.

Department of Companion and Laboratory Animal Science, Kongju National University, Yesan, Chungcheongnam 32439, Republic of Korea.

Dendropanax morbifera (D. morbifera), known as Dendro, means 'omnipotent drug' (Panax), and has been called the panacea tree. Various studies on D. Read More

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http://dx.doi.org/10.3892/mmr.2019.9887DOI Listing
January 2019

Contact allergy in children with atopic dermatitis: a retrospective study.

Endocr Metab Immune Disord Drug Targets 2019 Feb 11. Epub 2019 Feb 11.

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, IT-70124 Bari. Italy.

Backgound: The relationship between atopic dermatitis and allergic contact dermatitis is frequently debated, particularly in children. The impaired skin barrier of atopic subjects can facilitate the penetration of exogenous agents and its mutations in filaggrin gene might be implicated in an increased risk to develop contact dermatitis. Moreover, atopic children are protractedly exposed to chemical substances contained in skincare products from an early age. Read More

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http://www.eurekaselect.com/169857/article
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http://dx.doi.org/10.2174/1871530319666190211123342DOI Listing
February 2019
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Complete Genome Sequence of CBS 7877, an Opportunist Pathogen Involved in Dandruff and Seborrheic Dermatitis.

Microbiol Resour Announc 2019 Feb 7;8(6). Epub 2019 Feb 7.

L'Oréal Research and Innovation, Aulnay-sous-Bois, France.

Malassezia restricta, one of the predominant basidiomycetous yeasts present on human skin, is involved in scalp disorders. Here, we report the complete genome sequence of the lipophilic Malassezia restricta CBS 7877 strain, which will facilitate the study of the mechanisms underlying its commensal and pathogenic roles within the skin microbiome. Read More

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http://dx.doi.org/10.1128/MRA.01543-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368656PMC
February 2019

Superantigens of Colonization in Atopic Dermatitis and Treatment Efficacy of Oral Cefuroxim in Vietnamese Patients.

Open Access Maced J Med Sci 2019 Jan 20;7(2):243-246. Epub 2019 Jan 20.

University of Rome G. Marconi, Rome, Italy.

Background: Atopic dermatitis (AD) is a common, chronic, relapsing, genetically determined inflammatory skin disorder. Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of AD. Read More

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http://dx.doi.org/10.3889/oamjms.2019.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364715PMC
January 2019

Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis in Vietnamese Adults Patients.

Open Access Maced J Med Sci 2019 Jan 20;7(2):224-226. Epub 2019 Jan 20.

University of Rome G. Marconi, Rome, Italy.

Aim: This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients.

Methods: Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. Read More

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http://dx.doi.org/10.3889/oamjms.2019.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364731PMC
January 2019

Using Patch Testing to Improve Therapeutic Outcome in the Treatment of Hand Eczema in Vietnamese Patients.

Open Access Maced J Med Sci 2019 Jan 23;7(2):204-207. Epub 2019 Jan 23.

University of Rome G. Marconi, Rome, Italy.

Background: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. Read More

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http://dx.doi.org/10.3889/oamjms.2019.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364736PMC
January 2019
1 Read

Distribution of Malassezia Species from Scales of Patient with Pityriasis Versicolor by Culture in Vietnam.

Open Access Maced J Med Sci 2019 Jan 28;7(2):184-186. Epub 2019 Jan 28.

Psoriasis Eczema Clinic, Melbourne, Australia.

Background: The detection of pathogenic fungus is an important step and key to assessing the sensitivity of the antifungal drugs, and therefore choosing an effective treatment method.

Aim: To identify Malassezia species from scales of a patient with pityriasis versicolor.

Methods: Three hundred patients with pityriasis versicolor who were positive with direct examination, were isolated by culture. Read More

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http://dx.doi.org/10.3889/oamjms.2019.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364713PMC
January 2019

Antibiotic Resistance in Bacterial Infected Eczema at Ho Chi Minh City Hospital of Dermatology.

Open Access Maced J Med Sci 2019 Jan 27;7(2):181-183. Epub 2019 Jan 27.

University of Rome G. Marconi, Rome, Italy.

Background: Infected eczema is one of the most common complications of eczema. The progression and treatment of infected eczema have become more complex and difficulty due to the antibiotic resistance of bacteria and the abuse of antibiotics in treatment.

Aim: Our research was conducted with the aim of investigating the severity of in vitro antibiotic resistance in patients with bacterially infected eczema at Ho Chi Minh City Hospital of Dermatology. Read More

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http://dx.doi.org/10.3889/oamjms.2019.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364728PMC
January 2019
1 Read

The Curious Cases of Burn by Fig Tree Leaves.

Indian J Dermatol 2019 Jan-Feb;64(1):71-73

Cardiac Anesthesia Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Phytophotodermatitis is a condition which is caused by contact with some plants containing furocoumarins. Furocoumarins in sap of fig tree are the main cause of its irritability when come in contact with the skin. The main symptoms are burning sensation and pain, itchy erythema, and edema, which usually begin 24 h after exposure. Read More

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http://dx.doi.org/10.4103/ijd.IJD_442_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340245PMC
February 2019
5 Reads

Evaluation of Peripheral Blood Eosinophilia in Adolescent and Adult Patients Suffering from Atopic Dermatitis and the Relation to the Occurrence of Allergy to Aeroallergens.

Indian J Dermatol 2019 Jan-Feb;64(1):34-40

Department of Clinical Immunology and Allergy, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Background: Eosinophils play an important pathogenic role in atopic dermatitis (AD), but its exact function remains to be determined.

Aims And Objectives: The aim of this study was to correlate the eosinophil count with the manifestations such as asthma bronchiale, rhinitis, level of total IgE, sensitization to mites, animal dander, bird feather, dust, mixture of grass, mixture of trees, mixture of fungi, duration of lesions (persistent or occasional during last year), family history about atopy, and onset of AD (under or above 5 year of age).

Materials And Methods: Two hundred and seventy-two patients suffering from AD at the age of 14 year or older were examined - 100 men and 172 women with the average age of 26. Read More

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http://dx.doi.org/10.4103/ijd.IJD_509_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340239PMC
February 2019
1 Read

Microbiosis in pathogenesis and intervention of atopic dermatitis.

Int Immunopharmacol 2019 Feb 8;69:263-269. Epub 2019 Feb 8.

Department of Dermatology, Third Xiangya Hospital of Central South University, Changsha, Hunan 41006, China. Electronic address:

Atopic dermatitis (AD) is a chronic, non-contagious, inflammatory skin disorder characterized by relapsing eczematous lesions. Its pathogenesis remains incompletely understood. The current evidence has emerged to show that skin and gut microbiome play critical roles in the pathogenesis and progression of AD. Read More

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http://dx.doi.org/10.1016/j.intimp.2019.01.030DOI Listing
February 2019

Effect of the Fexofenadine on the expression of HRH-1 and HRH-4 receptor in Peripheral Blood Mononuclear Cell isolated from children with diagnosed allergy - in vitro study Short communication.

J Pharm Pharm Sci 2019 ;22(1):93-97

Department of Biology and Biotechnology, University of Warmia and Mazury, Oczapowskiego 1A Street, 10-719 Olsztyn, Poland.

Purpose: Fexofenadine (FXF) is the active metabolite of terfenadine with selective peripheral H1 receptor antagonist activity. FXF is a third-generation antihistamine, non-sedating, rapid and very long acting used in symptoms associated with allergic diseases such as allergic rhinitis, asthma and dermatitis. The pleiotropic effects of histamine are mediated by four types of receptors that belong to the G-protein-coupled receptor family: histamine H1 receptor (HRH-1), histamine H2 receptor, histamine H3 receptor, and histamine H4 receptor. Read More

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http://dx.doi.org/10.18433/jpps29971DOI Listing
January 2019
2 Reads

Protective effect of a topical sunscreen formulation fortified with melatonin against UV-induced photodermatitis: an immunomodulatory effect via NF-κB suppression.

Immunopharmacol Immunotoxicol 2019 Feb 11:1-10. Epub 2019 Feb 11.

a Division of Pharmaceutical Technology , Defence Research Laboratory , Tezpur , India.

Objective: Melatonin and pumpkin seed oil, along with US FDA approved UV filters were incorporated into a formulation for enhancement of UV protection by exerting an antioxidant effect. The objective of this study was to assess the protective effect of this formulation against ultraviolet (UV) radiation-induced photo dermatitis in rats, which is an established model to study the aetiopathogenic mechanisms in psoriasis vulgaris, as the former exhibits the same features to those of clinical psoriasis vulgaris in humans.

Materials And Methods: The animals were segregated into five groups (6/group) and all received their respective formulations dermally prior to chronic UV irradiation for 28 days. Read More

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http://dx.doi.org/10.1080/08923973.2019.1566358DOI Listing
February 2019
1.109 Impact Factor

NIPAL4 deletion identified in an American Bully with autosomal recessive congenital ichthyosis and response to topical therapy.

Vet Med Sci 2019 Feb 11. Epub 2019 Feb 11.

U955 - IMRB, Team 10 - Biology of the neuromuscular system, Inserm, UPEC, Ecole nationale vétérinaire d'Alfort, Maisons-Alfort, France.

Ichthyoses represent a heterogeneous group of hereditary cornification disorders characterized by generalized scaling of the skin. An autosomal recessive congenital ichthyosis (ARCI) has been described in American Bulldogs and is caused by a variant in the NIPAL4 gene encoding for the ICHTHYIN protein. So far, this variant has not been described in other breeds. Read More

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http://dx.doi.org/10.1002/vms3.149DOI Listing
February 2019