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    610 results match your criteria Dermal Fillers

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    Safety and Effectiveness of Juvéderm Ultra Plus Injectable Gel in Correcting Severe Nasolabial Folds in Chinese Subjects.
    Plast Reconstr Surg Glob Open 2017 Jan 16;5(1):e1133. Epub 2017 Jan 16.
    Peking University Third Hospital, Beijing, China (D.L.); Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China (Y.X., Qingfeng Li); General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guang Dong, China (Qin Li); Union Hospital of Tongji Medical College of HUST, Wuhan, Hubei, China (J.S.); Nanfang Hospital, Southern Medical University, Guangzhou, China (P.J.); Allergan China, Beijing, China (Y.J.); and Allergan plc, Irvine, Calif., (D.K.M.).
    Background: Hyaluronic acid dermal fillers are effective in correcting severe nasolabial folds (NLFs) in non-Asian populations. We assessed safety and effectiveness of Juvéderm Ultra Plus in a Chinese population.

    Methods: This double-blind study randomized Chinese subjects with severe NLFs to Juvéderm Ultra Plus (24 mg/mL) in 1 NLF and Restylane injectable gel (20 mg/mL) in the other NLF. Read More

    Outcome of Dermal Grafting in the Management of Atrophic Facial Scars.
    J Cutan Aesthet Surg 2016 Oct-Dec;9(4):244-248
    Department of Dermatology, Venereology and Leprology, Bengaluru Medical College and Research Institute, Bengaluru, Karnataka, India.
    Background: Scars over the face are cosmetically and psychologically disturbing. Various techniques have been described and are being practiced in the management of these scars.

    Aims And Objectives: This study was undertaken to study the safety, effectiveness of using dermal grafts as fillers in the management of facial scars due to acne, chickenpox, trauma or any others. Read More

    Facial Contouring With Fillers, Neuromodulators, and Lipolysis to Achieve a Natural Look in Patients With Facial Fullness.
    J Drugs Dermatol 2016 Dec;15(12):1536-1542
    Background: The desire for and use of nonsurgical injectable esthetic facial treatments is on a rise in Asia. Recent advances, including more versatile facial fillers, refined injection techniques, and adoption of a global facial approach, have in turn contributed to improved patient outcomes and increased patient satisfaction. The sought after nonsurgical treatments include the use of botulinum toxin, con- touring of the face with soft tissue fillers, and thinning of the face with injection lipolysis. Read More

    [Hyaluronic acid rheology: Basics and clinical applications in facial rejuvenation].
    Ann Chir Plast Esthet 2017 Jan 6. Epub 2017 Jan 6.
    Service de chirurgie maxillofaciale et de chirurgie plastique, réparatrice et esthétique, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
    Hyaluronic acid (HA) is the most widely used dermal filler to treat facial volume deficits and winkles specially for facial rejuvenation. Depending on various areas of the face, filler is exposed to two different forces (shear deformation and compression/stretching forces) resulting from intrinsec and external mechanical stress. The purpose of this technical note is to explain how rheology, which is the study of the flow and deformation of matter under strains, can be used in our clinical practice of facial volumization with fillers. Read More

    Efficacy and safety of new dermal fillers.
    Cutis 2016 Nov;98(5):309-313
    Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    Many dermal fillers are available for various cosmetic rejuvenation purposes including but not limited to treatment of facial rhytides, nasolabial folds (NLFs), facial volume deficits, and lipoatrophy; facial contouring; and lip and/or cheek augmentation. To update clinicians on best practices, we review the efficacy and safety data on the most recently approved dermal fillers. Read More

    Current concepts in lip augmentation.
    Cutis 2016 Nov;98(5):325-329
    Weill Cornell Medical College, New York, New York, USA.
    Facial rejuvenation, particularly lip augmentation, has gained widespread popularity. An appreciation of perioral anatomy as well as the structural characteristics that define the aging face is critical to achieve optimal patient outcomes. Although techniques and technology evolve continuously, hyaluronic acid (HA) dermal fillers continue to dominate aesthetic practice. Read More

    The Facial Adipose Tissue: A Revision.
    Facial Plast Surg 2016 Dec 29;32(6):671-682. Epub 2016 Dec 29.
    Department of Anatomy, Ross University School of Medicine, Roseau, West Indies.
    Recent advantages in the anatomical understanding of the face have turned the focus toward the subcutaneous and deep facial fat compartments. During facial aging, these fat-filled compartments undergo substantial changes along with other structures in the face. Soft tissue filler and fat grafting are valid methods to fight the signs of facial aging, but little is known about their precise effect on the facial fat. Read More

    The Efficacy and Safety of HA IDF Plus (with Lidocaine) Versus HA IDF (Without Lidocaine) in Nasolabial Folds Injection: A Randomized, Multicenter, Double-Blind, Split-Face Study.
    Aesthetic Plast Surg 2016 Dec 28. Epub 2016 Dec 28.
    Department of Plastic and Reconstructive Surgery, Soonchunhyang University Bucheon Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea.
    Background: Injection-related pain of dermal fillers is a consistent and bothersome problem for patients undergoing soft tissue augmentation. Reducing the pain could improve overall patient satisfaction.

    Objective: The purpose of this study was to compare the pain relief, efficacy, and safety of HA IDF plus containing lidocaine with HA IDF without lidocaine during correction of nasolabial folds (NLFs). Read More

    Ocular Pain and Impending Blindness During Facial Cosmetic Injections: Is Your Office Prepared?
    Aesthetic Plast Surg 2017 Feb 28;41(1):199-203. Epub 2016 Dec 28.
    Division of Plastic Surgery, Voluntary Clinical Faculty, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.
    Soft tissue filler injections are the second most common non-surgical procedure performed by the plastic surgeon. Embolization of intravascular material after facial injection is a rare but terrifying outcome due to the high likelihood of long-term sequela such as blindness and cerebrovascular accident. The literature is replete with examples of permanent blindness caused by injection with autologous fat, soft tissue fillers such as hyaluronic acid, PLLA, calcium hydroxyl-apatite, and even corticosteroid suspensions. Read More

    Disparities in Aesthetic Procedures Performed by Plastic Surgery Residents.
    Aesthet Surg J 2016 Dec 26. Epub 2016 Dec 26.
    From the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
    Background: Operative experience in aesthetic surgery is an important issue affecting plastic surgery residents.

    Objectives: This study addresses the variability of aesthetic surgery experience during plastic surgery residency.

    Methods: National operative case logs of chief residents in independent/combined and integrated plastic surgery residency programs were analyzed (2011-2015). Read More

    Late-Onset Complication of Fillers: Paraffinoma of the Lower Eyelids Clinically Mimicking Xanthelasma.
    Ann Dermatol 2016 Dec 23;28(6):753-756. Epub 2016 Nov 23.
    Department of Dermatology, SMG-SNU Boramae Medical Center, Seoul, Korea.
    Injectable poly-L-lactic acid (PLLA) is world-famous filler used in lipoatrophy and facial rejuvenation because of its collagen neogenesis effect which leads to gradual volume restoration. Until recently, quite a number of unwanted adverse events of PLLA have been reported. However, to the best of our knowledge, paraffinoma as a complication of PLLA has never been reported. Read More

    Filler migration to the forehead due to multiple filler injections in a patient addicted to cosmetic fillers.
    J Cosmet Laser Ther 2017 Jan 25:1-3. Epub 2017 Jan 25.
    a Department of Dermatology , Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan.
    Filler migration is a potential complication following the injection of multiple fillers. With the increasing popularity of multiple filler injections, migrated granulomas should be an essential differential diagnosis for newly growing facial lumps. It is important for all physicians to be aware that complication induced by dermal fillers can occur in locations other than the planned injected sites. Read More

    Safety and performance of cohesive polydensified matrix hyaluronic acid fillers with lidocaine in the clinical setting - an open-label, multicenter study.
    Clin Cosmet Investig Dermatol 2016 20;9:373-381. Epub 2016 Oct 20.
    Rosenparkklinik GmbH, Darmstadt, Germany.
    Cohesive polydensified matrix (CPM(®)) hyaluronic acid fillers are now available with or without lidocaine. The aim of this study was to investigate the safety and performance of CPM(®) fillers with lidocaine in the clinical setting. In an open-label, prospective, postmarketing study, 108 patients from seven sites in Germany and Denmark were treated with one or more lidocaine-containing CPM(®) fillers. Read More

    Dermal fillers: pathophysiology, prevention and treatment of complications.
    J Eur Acad Dermatol Venereol 2016 Sep 23. Epub 2016 Sep 23.
    Department of Surgery and Laser Unit, St. John's Institute of Dermatology, Guy's and St. Thomas' Hospitals, London, UK.
    Dermal fillers are increasingly used for soft tissue augmentation of the face and hands. The widespread use of dermal fillers for rejuvenation has led to a rise in reports of associated complications. Although the majority of complications are mild and transient, serious and long-lasting complications have been observed. Read More

    Safety and Long-Term Efficacy of Forehead Contouring With a Polycaprolactone-Based Dermal Filler.
    Dermatol Surg 2016 Nov;42(11):1256-1260
    Hus-Hu Dermatology Clinic, Seoul, Korea.
    Background: Recently, a biostimulatory dermal filler based on polycaprolactone (PCL) microspheres was introduced. To our knowledge, no report has examined the safety and efficacy of PCL-based dermal fillers in forehead augmentation.

    Objective: To evaluate the safety and efficacy of forehead augmentation using a PCL-based dermal filler. Read More

    Rejuvenation of the perioral and lip regions with two new dermal fillers: The Italian experience with Vycross(™) Technology.
    J Cosmet Laser Ther 2017 Feb 23;19(1):54-58. Epub 2016 Nov 23.
    c Plastic Surgeon , Verona , Italy.
    Background: Hyaluronic acid fillers are frequently used for maintenance of youthful appearance of perioral and lip region. The introduction of Juvederm(®) Volbella(™) with lidocaine and Juvederm(®) Volift(™) with lidocaine to the European aesthetic market in 2012 increased the options of fillers to be used and it appears to be a new solution to improve this area.

    Objective: the aim of this study is to demonstrate how to correct this area using two new dermal fillers: Juvederm(®) Volift(™) with lidocaine, and Juvederm(®) Volbella(™) with lidocaine, based on the experience of two Italian phycians. Read More

    Delayed Adverse Subcutaneous Reaction to a New Family of Hyaluronic Acid Dermal Fillers With Clinical, Ultrasound, and Histologic Correlation.
    Dermatol Surg 2016 Sep 28. Epub 2016 Sep 28.
    Pérez & Gavín dermatólogos Clinic, Vigo, Spain Department of Radiology Department of Dermatology, Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues, Clinica Servet, University of Santiago de Chile, Santiago de Chile, Chile Service of Dermatology, Department of Pathology, Hospital Universitario de Salamanca Salamanca, Spain.

    Hyaluronic acid fillers with cohesive polydensified matrix for soft-tissue augmentation and rejuvenation: a literature review.
    Clin Cosmet Investig Dermatol 2016 8;9:257-80. Epub 2016 Sep 8.
    Victoria Park Clinical Research Centre, Westmount, QC, Canada.
    Background: Cohesive monophasic polydensified fillers show unique viscoelastic properties and variable density of hyaluronic acid, allowing for a homogeneous tissue integration and distribution of the material.

    Objective: The aim of this paper was to review the clinical data regarding the performance, tolerability, and safety of the Belotero(®) fillers for soft-tissue augmentation and rejuvenation.

    Methods: A literature search was performed up until May 31, 2015 to identify all relevant articles on Belotero(®) fillers (Basic/Balance, Hydro, Soft, Intense, Volume) and equivalent products (Esthélis(®), Mesolis(®), Fortélis(®), Modélis(®)). Read More

    Volume correction in the aging hand: role of dermal fillers.
    Clin Cosmet Investig Dermatol 2016 30;9:225-32. Epub 2016 Aug 30.
    David Geffen/UCLA School of Medicine Los Angeles, CA, USA.
    The hands, just like the face, are highly visible parts of the body. They age at a similar rate and demonstrate comparable changes with time, sun damage, and smoking. Loss of volume in the hands exposes underlying tendons, veins, and bony prominences. Read More

    Effect of molecular weight of hyaluronic acid (HA) on viscoelasticity and particle texturing feel of HA dermal biphasic fillers.
    Biomater Res 2016 7;20(1):24. Epub 2016 Sep 7.
    Beautiful Revolution Co., Ltd., Seoul, 135-513 Republic of Korea.
    Background: Hyaluronic acid (HA) dermal biphasic fillers are synthesized for their efficacy in correcting aesthetic defects such as wrinkles, scars and facial contouring defects. The fillers consist of crosslinked HA microspheres suspended in a noncrosslinked HA. To extend the duration of HAs within the dermis and obtain the particle texturing feel, HAs are crosslinked to obtain the suitable mechanical properties. Read More

    A Randomized Clinical Trial of Comparing Monophasic Monodensified and Biphasic Nonanimal Stabilized Hyaluronic Acid Dermal Fillers in Treatment of Asian Nasolabial Folds.
    Dermatol Surg 2016 Sep;42(9):1061-8
    *All the authors are affiliated with the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
    Background: Cross-linked hyaluronic acids (HAs) with varying characteristics and formulations are available. Despite the popularity of HA, limited studies compared the effectiveness of monophasic monodensified hyaluronic acid (MMHA) and biphasic nonanimal stabilized hyaluronic acid (BHA) products in correcting nasolabial folds (NLFs) in the Asian population.

    Objective: This double-blinded, randomized research aimed at evaluating the outcomes of MMHA and BHA products in treating Asian NLFs. Read More

    Streptococcus sanguinis isolated from filler granuloma: Successful treatment with incision and drainage.
    Dermatol Ther 2016 Nov 19;29(6):463-465. Epub 2016 Aug 19.
    Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
    Filler granuloma is considered to be the result of delayed immune responses; growing evidence suggests that they may be secondary to biofilm formation. Dermal filler is technically a foreign body, and as the development of newer generations of dermal fillers lengthens their duration, it is possible that there is also an increased risk of biofilm formation. Here, we present a case report of a patient with Streptococcus sanguinis isolated from a filler granuloma, suggestive of biofilm formation. Read More

    Calcium Hydroxylapatite With Integral Lidocaine Provides Improved Pain Control for the Correction of Nasolabial Folds.
    J Drugs Dermatol 2016 Aug;15(8):1005-10
    Calcium hydroxylapatite microspheres in a carrier gel (CaHA; Radiesse®: Merz North America, Inc., Raleigh, NC) is approved by the United States Food and Drug Administration for subdermal implantation for the correction of moderate-to-severe facial wrinkles and folds, such as nasolabial folds (NLFs). Lidocaine is often mixed with injectable dermal fillers to reduce injection pain. Read More

    The Aging Face: Global Approach With Fillers and Neuromodulators.
    Semin Cutan Med Surg 2016 Jun;35(6 Suppl):S120-1
    Assistant Professor University of Toronto Toronto, Ontario, Canada.
    The goal of treating the aging face is to restore facial balance and modify shadows. A facial evaluation should focus on areas of volume loss and opportunities to use neuromodulators (eg, botulinum toxin A) and the use of fillers. A thorough understanding of facial anatomy, including muscles, nerves, bone, and fat pads, is essential for effective and safe treatment. Read More

    Fillers: What's Here and What's Ahead.
    Semin Cutan Med Surg 2016 Jun;35(6 Suppl):S117-9
    Assistant Professor University of Toronto Toronto, Ontario, Canada.
    Soft tissue augmentation products (or fillers) are used for the correction of age-related changes in areas of the face. The most common filler material is hyaluronic acid, which is synthetically cross-linked. These materials are generally safe, but some side effects do occur. Read More

    Biophysical and biological characterization of a new line of hyaluronan-based dermal fillers: A scientific rationale to specific clinical indications.
    Mater Sci Eng C Mater Biol Appl 2016 Nov 7;68:565-72. Epub 2016 Jun 7.
    Department of Experimental Medicine, Section of Biotechnology, Medical Histology and Molecular Biology, Bioteknet Second University of Naples, Via L. De Crecchio 7, 80138 Naples, Italy. Electronic address:
    Chemico-physical and biological characterization of hyaluronan-based dermal fillers is of key importance to differentiate between numerous available products and to optimize their use. These studies on fillers are nowadays perceived as a reliable approach to predict their performance in vivo. The object of this paper is a recent line of hyaluronic acid (HA)-based dermal fillers, Aliaxin®, available in different formulations that claim a complete facial restoration. Read More

    Penile Girth Enhancement With Polymethylmethacrylate-Based Soft Tissue Fillers.
    J Sex Med 2016 Sep 25;13(9):1414-22. Epub 2016 Jul 25.
    Avanti Derma, Tijuana, BC, Mexico.
    Introduction: An unknown percentage of men will take every risk to develop a larger penis. Thus far, most injectables have caused serious problems. Polymethylmethacrylate (PMMA) microspheres have been injected as a wrinkle filler and volumizer with increasing safety since 1989. Read More

    Periorbital Injectables: Understanding and Avoiding Complications.
    J Cutan Aesthet Surg 2016 Apr-Jun;9(2):73-9
    Department of Ophthalmology, Division of Orbital & Oculofacial Plastic Surgery, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland OH, USA.
    Periorbital rejuvenation with neurotoxins and dermal fillers address several aging changes. Safe and effective results require a thorough understanding of periorbital anatomy, proper injection techniques, and complications of these products. Prompt recognition and treatment of complications can minimize their adverse impacts. Read More

    Synthetic Fillers for Facial Rejuvenation.
    Clin Plast Surg 2016 Jul;43(3):497-503
    Lorenc Aesthetic Plastic Surgery Center, 983 Park Avenue, New York, NY 10028, USA.
    Soft tissue filler procedures have increased dramatically in popularity in the United States. Synthetic fillers such as calcium hydroxyapatite (CaHA), polymethyl methacrylate (PMMA), and poly-l-lactic acid (PLLA), and silicone provide initial volume replacement but have an additional biostimulatory effect to supplement facial volumization. Indications include human immunodeficiency virus lipoatrophy and nasolabial folds for CaHA and PLLA and atrophic acne scars for PMMA. Read More

    Hyaluronic Acid Fillers: Science and Clinical Uses.
    Clin Plast Surg 2016 Jul 5;43(3):489-96. Epub 2016 May 5.
    Division of Plastic Surgery, University of Illinois, Chicago, IL 60611, USA. Electronic address:
    Hyaluronic acid soft tissue fillers include a range of products (Juvederm Ultra, Juvederm Ultra Plus, Voluma, Restylane Silk, Restylane, Restylane Lyft, and Belotero Balance) that are used commonly for facial rejuvenation and enhancement of facial features. Although these products are similar in many ways, they are not interchangeable and have unique characteristics that need to be considered. Injection sites and techniques for facial rejuvenation are discussed. Read More

    Fat, Stem Cells, and Platelet-Rich Plasma.
    Clin Plast Surg 2016 Jul;43(3):473-88
    Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA; Department of Bioengineering, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15261, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address:
    The ideal filler for aesthetic surgery is inexpensive and easy to obtain, natural in appearance and texture, immunologically compatible, and long lasting without risk of infection. By most metrics, autologous fat grafts meet these criteria perfectly. Although facial fat grafting is now a commonly accepted surgical procedure, there has been a wave of activity applying stem cells and platelet-rich plasma (PRP) therapies to aesthetic practice. Read More

    Incorporating Minimally Invasive Procedures into an Aesthetic Surgery Practice.
    Clin Plast Surg 2016 Jul;43(3):449-57
    Park Avenue Skin Solutions, 1009 Park Avenue, New York, NY 10028, USA.
    Minimally invasive procedures in an aesthetic practice have grown over the past decade. Plastic surgery practices are embracing the incorporation of injectables and lasers as adjuncts to their surgical procedures. The use of botulinum toxin, hyaluronic acid fillers, and lasers has made a significant impact on the authors' practice. Read More

    Hand rejuvenation: Combining dorsal veins foam sclerotherapy and calcium hydroxylapatite filler injections.
    Phlebology 2016 Jun 24. Epub 2016 Jun 24.
    Central Sydney Dermatology, Sydney, Australia St George Dermatology, Kogarah, Australia
    Background: The hands are an important aesthetic feature that can reveal aging through surface pigmentary changes, loss of skin thickness and ectatic dorsal hand veins. Techniques addressing these changes already exists but are not routinely combined for optimum results.

    Objective: The combination techniques of dorsal hand veins sclerotherapy and sub-dermal filler injections are described. Read More

    Antimicrobial Activity of Starch Hydrogel Incorporated with Copper Nanoparticles.
    ACS Appl Mater Interfaces 2016 Jun 20;8(25):16280-8. Epub 2016 Jun 20.
    Cátedra de Química Analítica Instrumental, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires , Junín 956, C1113AAD Buenos Aires, Argentina.
    In order to obtain an antimicrobial gel, a starch-based hydrogel reinforced with silica-coated copper nanoparticles (Cu NPs) was developed. Cu NPs were synthesized by use of a copper salt and hydrazine as a reducing agent. In order to enhance Cu NP stability over time, they were synthesized in a starch medium followed by a silica coating. Read More

    Experience and Management of Intravascular Injection with Facial Fillers: Results of a Multinational Survey of Experienced Injectors.
    Aesthetic Plast Surg 2016 Aug 10;40(4):549-55. Epub 2016 Jun 10.
    Private Practice, Geelong, VIC, Australia.
    Background: Intravascular injection leading to skin necrosis or blindness is the most serious complication of facial injection with fillers. It may be underreported and the outcome of cases are unclear. Early recognitions of the symptoms and signs may facilitate prompt treatment if it does occur avoiding the potential sequelae of intravascular injection. Read More

    A Randomized, Evaluator-Blinded, Split-Face Comparison Study of the Efficacy and Safety of a Novel Mannitol Containing Monophasic Hyaluronic Acid Dermal Filler for the Treatment of Moderate to Severe Nasolabial Folds.
    Ann Dermatol 2016 Jun 25;28(3):297-303. Epub 2016 May 25.
    Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
    Background: Mannitol containing monophasic filler with higher crosslinking has not been well studied for moderate and severe nasolabial fold (NLF) correction.

    Objective: To compare the efficacy and safety of a novel mannitol containing hyaluronic acid (HA) filler (HA-G) with biphasic HA filler (HA-P) for moderate and severe NLF correction.

    Methods: Thirteen subjects with symmetric moderate to severe NLF received HA-G (in one NLF) and HA-P (in other NLF) and were evaluated for 24 weeks. Read More

    An Inquiry Into the Role of the Aesthetic Nurse: "Should Nurses Sell?".
    Plast Surg Nurs 2016 Apr-Jun;36(2):81-3
    Iris Epstein, RN, PhD, is Professor in Nursing, George Brown College, Sally Horsfall Eaton School of Nursing, Toronto, Ontario, Canada.
    I am a registered nurse, working for more than a decade. In the last few years, I decided to pursue my passion in the field of medical aesthetics. I invested in learning new skills through training and certification programs and was excited to attain employment in my chosen field. Read More

    Xanthelasma-Like Reaction to Filler Injection.
    Ophthal Plast Reconstr Surg 2016 May 23. Epub 2016 May 23.
    *Assaf Harofeh Medical Center, Tzrifin, Israel; †Chelsea Eye and Cosmetic Surgery, New York, New York, ‡University of Southern California, Los Angeles, California, U.S.A.; and §Oculoplastica Bernardini, Milan, Italy.
    Purpose: The purpose of this study is to describe a new complication of a xanthelasma-like reaction which appeared after dermal filler injection in the lower eyelid region.

    Methods: A retrospective case analysis was performed on 7 patients presenting with xanthelasma-like reaction after filler injection to the lower eyelids.

    Results: Seven female subjects with no history of xanthelasma presented with xanthelasma-like reaction in the lower eyelids post filler injection. Read More

    Serious Vascular Complications after Nonsurgical Rhinoplasty: A Case Report.
    Plast Reconstr Surg Glob Open 2016 Apr 21;4(4):e683. Epub 2016 Apr 21.
    Division of Surgery and Interventional Science, University College London, London, United Kingdom; and Shenyang Friendship Cosmetic Surgery Hospital, Shenyang, China.
    There has been an increased global demand for dermal filler injections in recent years. Although hyaluronic acid-based dermal fillers generally have a good safety profile, serious vascular complications have been reported. Here we present a typical case of skin necrosis following a nonsurgical rhinoplasty using hyaluronic acid filler. Read More

    Long-lasting and bioactive hyaluronic acid-hydroxyapatite composite hydrogels for injectable dermal fillers: Physical properties and in vivo durability.
    J Biomater Appl 2016 Sep 9;31(3):464-74. Epub 2016 May 9.
    Department of Materials Science and Engineering, Seoul National University, South Korea Biomedical Implant Convergence Research Center, Advanced Institutes of Convergence Technology, South Korea
    Hyaluronic acid (HAc)-hydroxyapatite (HAp) composite hydrogels were developed to improve the biostability and bioactivity of HAc for dermal filler applications. Two kinds of HAc-HAp composite fillers were generated: HAcmicroHAp and HAc-nanoHAp composites. HAc-microHAp was fabricated by mixing HAp microspheres with HAc hydrogels, and HAc-nanoHAp was made by in situ precipitation of nano-sized HAp particles in HAc hydrogels. Read More

    Etiology, Prevention, and Management of Infectious Complications of Dermal Fillers.
    Semin Plast Surg 2016 May;30(2):83-6
    Division of Plastic and Reconstructive Surgery, Baylor College of Medicine, Houston, Texas.
    The demand for aesthetic augmentation with soft tissue fillers has greatly increased in recent years and has led to an expansion in the number of products available. Unfortunately, an increase in adverse events has followed. These can be categorized into early, late, and delayed. Read More

    Interactions of Staphylococcus aureus with ultrasoft hydrogel biomaterials.
    Biomaterials 2016 Jul 14;95:74-85. Epub 2016 Apr 14.
    United States Food and Drug Administration, Office of Medical Products and Tobacco, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Biology, Chemistry and Materials Science, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA. Electronic address:
    Ultrasoft biomaterials-polymers, gels, and human soft tissues with an elastic modulus less than ∼100 kPa-are increasingly used in medical devices. While bacterial interactions (adhesion and biofilm formation) have been extensively studied on stiffer materials, little is known about how bacteria colonize ultrasoft materials as a nidus for infection. The goal of this work was to determine how material properties of ultrasoft hydrogels used for dermal fillers might affect pathogenesis of associated infections. Read More

    Neck Rejuvenation Using a Combination Approach: Our Experience and a Review of the Literature.
    Dermatol Surg 2016 May;42 Suppl 2:S94-S100
    *Department of Dermatology, University of Illinois at Chicago, Chicago, Illinois; †Goldman, Butterwick, Groff, Fabi, & Wu Cosmetic Laser Dermatology, San Diego, California; ‡Department of Medicine/Dermatology, University of California, San Diego, California; §Department of Dermatology, University of North Carolina, Chapel Hill, North Carolina; ‖Department of Dermatology, Duke University, Durham, North Carolina.
    Background: Aging of the neck is characterized by changes that include skin dyspigmentation, laxity, rhytides, loss of the mandibular contour, widening of the cervicomental angle, accumulation of submental fat, volume loss and prominence of the platysmal bands. Many cosmetic options exist to address these changes individually, but little literature exists about the safety and efficacy of combining such procedures and devices.

    Objective: To review the existing literature and the authors' experience in safely and effectively combining aesthetic rejuvenation modalities for the neck. Read More

    Combining Microfocused Ultrasound With Botulinum Toxin and Temporary and Semi-Permanent Dermal Fillers: Safety and Current Use.
    Dermatol Surg 2016 May;42 Suppl 2:S168-76
    *Dermatology Cosmetic Laser Medical Associates of La Jolla, San Diego, California; †Aesthetic Plastic Surgical Institute, Laguna Beach, California; ‡Premier Clinical Research, Spokane, Washington; §Skin Associates of South Florida, Coral Gables, Florida; ‖Maryland Laser Skin and Vein Institute, Hunt Valley, Maryland; ¶Apothekon Inc., Woodbury, Minnesota.
    Background: A microfocused ultrasound system with visualization (MFU-V) is currently indicated for use as a noninvasive dermatological aesthetic treatment to lift the eyebrows, lax submental and neck tissue, and improve lines and wrinkles of the décolleté.

    Objective: To determine the existence of any safety signals when combining MFU-V with botulinum toxin-A and/or semipermanent and temporary dermal fillers.

    Materials And Methods: A retrospective chart review was performed using subjects who received aesthetic treatments including incobotulinumtoxinA injection, cohesive polydensified matrix hyaluronic acid (CPM HA) dermal fillers, and calcium hydroxylapatite (CaHA) dermal fillers within 6 months of treatment with MFU-V in the same or different anatomic areas. Read More

    Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type.
    Dermatol Surg 2016 May;42 Suppl 2:S139-49
    *Cosmetic Laser Dermatology, San Diego, California; †Department of Dermatology, University of California, San Diego, California; ‡Gateway Aesthetic Institute & Laser Center, Salt Lake City, Utah.
    Background: Acne scarring can be classified into atrophic icepick, boxcar, and rolling scars in addition to keloidal and hypertrophic scars. Additionally, these scars can be erythematous, hyperpigmented, and/or hypopigmented. Each scar type has a different structural cause warranting a customized approach. Read More

    Current Applications of Facial Volumization with Fillers.
    Plast Reconstr Surg 2016 May;137(5):872e-89e
    Philadelphia, Pa. From the University of Pennsylvania, School of Medicine.
    Learning Objectives: After reading this article and watching the accompanying videos, the participant should be able to: 1. Assess patients seeking facial volumization and correlate volume deficiencies anatomically. 2. Read More

    Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A-Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations.
    Plast Reconstr Surg 2016 May;137(5):1410-23
    Rockville, Md.; Sydney, New South Wales, Australia; Milan, Italy; Rio de Janeiro and Sao Paulo, Brazil; Boca Raton, Fla.; Montreal, Quebec, Canada; Aalst, Belgium; Cannes, France; and Birmingham, Ala.
    Background: Combination of fillers and botulinum toxin for aesthetic applications is increasingly popular. Patient demographics continue to diversify, and include an expanding population receiving maintenance treatments over decades.

    Methods: A multinational panel of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated guidelines with a worldwide perspective for hyaluronic acid fillers and botulinum toxin. Read More

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