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J Drugs Dermatol 2021 May;20(5):519-522

Background: Dinoprostone (DNP), a prostaglandin E2 (PGE2) analogue, has been found to cause repigmenation in vitiliginous lesions. Combined medical and surgical therapy might be more useful for successful treatment of vitiligo.

Objectives: In this study, we aimed to evaluate the efficacy and safety of dermabrasion followed by dinoprostone gel and to compare it with tacrolimus ointment following the same procedure in the treatment of localized stable vitiligo. Read More

J Cutan Aesthet Surg 2020 Oct-Dec;13(4):338-339

Medical Trust Hospital, Kochi, Kerala, India.

Adequate dermabrasion of recipient site is a crucial step in vitiligo surgery. We suggest the use of a commercially available mechanized abrader as an economical and efficient tool for dermabrasion especially in resource poor settings. Read More

Dermatology 2021 Apr 23:1-3. Epub 2021 Apr 23.

The Skin Hospital, Sydney, New South Wales, Australia.

Autologous non-cultured epidermal cellular grafting is the treatment of choice for patients with stable refractory vitiligo. Recently, studies have shown cost-effective alternatives for this procedure, superseding previous techniques that required large research facilities or expensive pre-packaged kits. We provide modifications to current techniques, including the use of individual Petri dishes to allow for processing larger skin grafts, hyfrecation instead of conventional manual dermabrasion of the recipient site to reduce scar formation as well as better margin delineation, and an intravenous giving set with a filter for improved filtration of the mixed cell population. Read More

Regen Ther 2021 Dec 14;18:1-6. Epub 2021 Mar 14.

Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyou-ku, Kyoto, 606-8507, Japan.

Introduction: Curettage and dermabrasion are effective in the treatment of giant congenital melanocytic nevi (GCMN); however, local infection and hypertrophic scar formation are major issues. Thus, we applied cultured epithelial autografts (CEA) on skin defects after curettage or abrasion of GCMN and assessed the postoperative outcomes.

Methods: Seven nevi lesions of five patients (aged 3 months to 24 years) were treated with CEA after curettage or abrasion with a dermatome or a surgical bar, respectively. Read More

Facial Plast Surg 2021 Apr 3;37(2):149-159. Epub 2021 Mar 3.

PLLC-Otolaryngology Division, Rochester, New York.

Facial aging in the midface has been described to encompass both soft tissue descent and volumetric change. Currently, there is no established and widely accepted grading system for midfacial ptosis. We propose a simplified grading system for midfacial ptosis ranging from mild to severe in terms of Grades I through III. Read More

G Ital Dermatol Venereol 2020 Dec;155(6):780-782

Department of Legal Medicine, IRCCS San Martino University Hospital, Genoa, Italy.

The possible transformation of a giant congenital melanocytic nevi (GCMN) in malignant melanoma estimated from 0.05% to 40% depend on the size of the lesions. Many are the surgical procedures proposed, including: full or partial-thickness excisions, dermabrasion, curettage in the first weeks of life and laser treatment. Read More

Indian J Dermatol Venereol Leprol 2021 Jan-Feb;87(1):14-21

Department of Dermatology, Saint George Hospital University Medical Center, Beirut, Lebanon.

Darier disease (DD) is a rare type of inherited keratinizing disorder with no definitive therapeutic approach. The objective of this study is to provide a detailed literature review of all the available treatment modalities of Darier disease, including those that are both surgical and non surgical, to compare their efficacies and to propose a novel therapeutic approach. A complete search of the literature for all articles describing the different treatments of Darier disease, with no restrictions on patients' ages, gender or nationalities, was performed with the use of PubMed. Read More

J Infect Dis 2021 Feb 2. Epub 2021 Feb 2.

Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

Background: Cutaneous mold infections commonly result from an array of traumatic injuries that involve direct inoculation of contaminated soil into wounds. Here, we explored the use of antimicrobial blue light (aBL; 405 nm wavelength) and the combination of aBL with quinine hydrochloride (aBL + Q-HCL) for the treatment of cutaneous mold infections.

Methods: Efficacy of aBL and aBL + Q-HCL in killing clinically important pathogenic molds (Aspergillus fumigatus, Aspergillus flavus, and Fusarium oxyprorum) was investigated. Read More

Craniomaxillofac Trauma Reconstr 2020 Dec 11;13(4):305-312. Epub 2020 Sep 11.

Plastic, Micro & Craniofacial Surgery, Manipal Education and Medical Group International India Pvt Ltd, Bangalore, Karnataka, India.

Study Design: This is a prospective observational study of 60 consecutive cases with facial scars and contour deformity who underwent structural fat grafting.

Objectives: The aim of the present article is to highlight how fat grafting helps to improve aesthetic and functional outcome in facial scars and contour deformities. It also highlights the factors that need to be considered while planning autologous fat grafting to get better aesthetic results. Read More

Ann Ital Chir 2020 Oct 26;9. Epub 2020 Oct 26.

Background: Rhinophyma is a rare and benign pathological condition affecting the nose. It can be localized or generalized causing a nasal deformity, mainly of the lower 2/3 of the nose. Clinically, rhinophyma is characterized by the aberrant development of the vascularization of the skin of the nose. Read More

Dermatol Ther 2021 Mar 17;34(2):e14750. Epub 2021 Jan 17.

Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. Read More

Semin Plast Surg 2020 Nov 24;34(4):305-313. Epub 2020 Dec 24.

Otolaryngology and Facial Plastic Surgery Associates, Fort Worth, Texas.

The process of scar formation is a sequela of the healing following soft tissue injury extending to, or through, the reticular dermis. Scars, within the head and neck in particular, may be physically disfiguring with resultant psychosocial implications. Mitigation of excessive scar formation during the healing process following surgery, or in the setting of trauma, begins with meticulous soft tissue handling and reconstructive technique. Read More

Dermatol Ther 2021 Jan 27;34(1):e14683. Epub 2020 Dec 27.

Department of Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Noncultured epidermal cell suspension (NCES) is a well-established surgical treatment modality for stable vitiligo. The outcome of this procedure significantly depends on the method of recipient site preparation, a critical step to achieve cosmetically acceptable repigmentation. To compare the efficacy of recipient site preparation using three methods namely, dermabrasion, cryoblister, and dermaroller followed by NCES in stable vitiligo. Read More

Clin Cosmet Investig Dermatol 2020 11;13:949-955. Epub 2020 Dec 11.

Department of Medical Laser Applications, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.

Introduction: Rhinophyma is a cosmetic disorder that causes emotional distress if the symptoms are extensive or obvious enough. Treatment options range from topical antibiotics or isotretinoin, surgical resection, cryosurgery, electrocautery, dermabrasion and more recently laser therapy. With the limitations of surgical techniques, lasers gained popularity for treating rhinophyma. Read More

Burns 2020 Aug 29. Epub 2020 Aug 29.

Regional Burn Center, Lehigh Valley Health Network, Allentown, PA, USA.

Introduction: A new bio-degradable synthetic membrane was recently introduced to treat second degree burns in adults and pediatric patients.

Objective: To assess complications and outcomes using this absorbable synthetic membrane to treat second degree burns.

Methods: 229 burn patients, 138 pediatric, with superficial and deep second -degree wounds, treated with the absorbable synthetic membrane (Suprathel®, Polymedics, Denkendorf, Germany) were included in this study. Read More

Dermatol Surg 2021 01;47(1):86-93

Department of Dermatology, University of California, Irvine, Irvine, California.

Background: Surgical defects of the distal nose can pose significant reconstructive challenges. Free cartilage batten graft (FCBG) with secondary intention healing is an underreported yet effective repair option with cosmetically and functionally satisfying outcomes.

Objective: To share the authors' experience using FCBG with secondary intention healing on multiple nasal subunits, including a detailed evaluation of wound/graft characteristics and design modifications to optimize success with this single-stage approach. Read More

Zhonghua Shao Shang Za Zhi 2020 Oct;36(10):895-900

Natural dermal matrix has good biocompatibility and can serve as " biological template" in wound repair. According to the source of material, natural dermal matrix can be divided into acellular dermal matrix (ADM), denatured dermal matrix, and scar dermal matrix. ADM is a biological material prepared by removing cellular components from the skin and retaining extracellular matrix (ECM) of the dermis. Read More

J Am Acad Dermatol 2020 Oct 10. Epub 2020 Oct 10.

The Hospital for Skin Disease, Institute of Dermatology, Chinese Academy of Medical Science, Peking Union Medical College, Nanjing 210042, Jiangsu, China. Electronic address:

Capsule Summary: In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. Read More

Childs Nerv Syst 2020 10 13;36(10):2571-2596. Epub 2020 Oct 13.

Pediatric Neurosurgery, International Neuroscience Institute (INI), Hannover, Germany.

Neurocutaneous melanosis (NCM; MIM # 249400; ORPHA: 2481], first reported by the Bohemian pathologist Rokitansky in 1861, and now more precisely defined as neurocutaneous melanocytosis, is a rare, congenital syndrome characterised by the association of (1) congenital melanocytic nevi (CMN) of the skin with overlying hypertrichosis, presenting as (a) large (LCMN) or giant and/or multiple (MCMN) melanocytic lesions (or both; sometimes associated with smaller "satellite" nevi) or (b) as proliferative melanocytic nodules; and (2) melanocytosis (with infiltration) of the brain parenchyma and/or leptomeninges. CMN of the skin and leptomeningeal/nervous system infiltration are usually benign, more rarely may progress to melanoma or non-malignant melanosis of the brain. Approximately 12% of individuals with LCMN will develop NCM: wide extension and/or dorsal axial distribution of LCMN increases the risk of NCM. Read More

Dermatol Surg 2021 Apr;47(4):e142-e145

Department of Dermatovenerology, Guangzhou New Century Vitiligo Prevention and Control Research Institute, Guangzhou, China.

Background: Stable vitiligo has been treated by dermabrasion and noncultured epidermal cell suspension (NCES) effectively. However, not all patches respond well.

Objective: To investigate the efficacy of new pigmentation after medical treatment in the therapy of stable vitiligo. Read More

Facial Plast Surg Clin North Am 2020 Nov 9;28(4):493-501. Epub 2020 Sep 9.

Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, 340 West 10 th Street, Fairbanks Hall, Suite 6200, Indianapolis, IN 46202-3082, USA.

Skin resurfacing techniques allow improvement of skin texture and color. This includes the effacement of wrinkles, signs of photoaging, and the softening of scars. Laser resurfacing, chemical peels, and dermabrasion are associated with overlapping risks of complications. Read More

Dermatol Ther 2020 11 19;33(6):e14362. Epub 2020 Oct 19.

Department of Dermatology and Venereology, Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

There is a continuous need for modifications of epidermal cell grafting techniques treating stable vitiligo to make it easier, more economic, and with better outcome. To evaluate the efficacy and safety of noncultured, nontrypsinized epidermal cell graft homogenized with plasma gel, followed by narrow band-ultraviolet B (NB-UVB) in treatment of stable vitiligo, about 40 patients with stable vitiligo underwent harvesting of epidermal cells from the donor site by dermabrasion then the harvested cells were prepared, homogenized with autologous plasma gel, and applied to the abraded recipient, followed by 16 NB-UVB sessions after complete healing. Patches within the same anatomical site received only NB-UVB as controls. Read More

J Clin Aesthet Dermatol 2020 Jul 1;13(7):41-44. Epub 2020 Jul 1.

All authors are with the Department of Dermatology, University of California, Irvine, in Irvine, California.

Patients with Brooke-Spiegler Syndrome (BSS) can present with benign cylindromas, spiradenomas, spiradenocylindromas, and trichoepithelioma. Therapy options include excision, electrocautery, CO laser ablation, dermabrasion, and radiofrequency. Here, we present a patient with BSS with multiple trichoepitheliomas who was successfully treated with erbium:yttrium-aluminum-garnet (YAG) laser therapy and review similar cases of BSS treated with a YAG laser modality. Read More

J Cosmet Dermatol 2020 Nov 29;19(11):2812-2819. Epub 2020 Sep 29.

Dermatology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Background: Chemical peelings are used on a wide scale in cosmetic field including melasma treatment. They often provide clinicians with flexibility in tailoring treatments according to patient needs and satisfaction.

Objective: To evaluate safety and efficacy of chemical peeling as single agents in melasma management in patients with darker skin types. Read More

Dermatol Ther 2020 11 28;33(6):e14267. Epub 2020 Sep 28.

Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

Androgenetic alopecia (AGA) is an androgen-dependent hereditary trait resulting in hair miniaturization. It is the most common type of alopecia in men and women. During the last years, multiple treatment modalities have been studied, but only topical minoxidil and finasteride have been approved by the US Food and Drug Administration. Read More

Arch Craniofac Surg 2020 Aug 20;21(4):264-267. Epub 2020 Aug 20.

Department of Plastic and Reconstructive Surgery, Jeju National University School of Medicine, Jeju, Korea.

Rhinophyma is a painless benign tumor of the skin of the nose. It is the most severe form of rosacea. Rhinophyma is particularly rare among Asians. Read More

Cell Tissue Bank 2021 Mar 30;22(1):39-46. Epub 2020 Aug 30.

Department of Burns and Reconstructive Surgery, Faculty of Medicine, Comenius University, University Hospital, Pazitkova 4, 821 01, Bratislava, Slovakia.

Mesenchymal stem cells (MSCs) are multi-potent cells characterized by long term self-renewal and by potential for differentiation into cells of different mesenchymal tissue types such as fibroblasts, osteocytes, chondrocytes, and adipocytes. Their unique properties offer broad therapeutic potentials. Bone marrow has been used as the most common MSCs source, but it is gradually going to be replaced by adipose tissue which showed to contain more MSCs per unit than the bone marrow and clinical application of MSCs procured from the adipose tissue have been demonstrating at least similar results. Read More

Aesthetic Plast Surg 2020 12 6;44(6):2277-2285. Epub 2020 Aug 6.

Department of Medical, Oral and Biotechnological Sciences and CAST, University of Chieti-Pescara, Via Dei Vestini 31, 66100, Chieti, Italy.

Objectives: The face aging processes are associated with physiologic and biochemical alteration that produces wrinkles, skin pigmentation and benign growths. The aim of this study was to evaluate the clinical efficacy of voltaic arc dermabrasion with plasma to remove benign facial skin lesions.

Study Design: Voltaic arc dermabrasion plasma technique was used to remove the facial benign skin lesions. Read More

Int J Surg Case Rep 2020 18;72:511-514. Epub 2020 Jun 18.

Department of Surgery, Texas Tech University Health Sciences Center, El Paso, TX, United States. Electronic address:

Introduction: Rhinophyma is benign hypertrophic thickening of the skin and edema of the nasal pyramid. The affected tissue enlarges slowly before reaching its permanent size. The lobulated skin surface with hundreds of pores can become cosmetically embarrassing and cause significant psychosocial stress, anxiety, and depression for patients. Read More

Acta Dermatovenerol Croat 2020 Jul;28(1):47-48

Nikolina Jurišić, MD,

Dear Editor, The diagnosis of malignant melanoma accounts for 1-2% of all cancer diagnoses, around 4% of all malignant skin diseases, and 80% of all skin cancer deaths (1). The prognosis depends on several factors including tumor size, Clark level, Breslow thickness, location, ulceration, and presence of metastases. Detection of lymph node metastasis is initially accomplished by clinical examination and by operative evaluation for occult metastasis using sentinel lymph node biopsy (SLNB) when indicated (2). Read More