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Urologe A 2019 Feb 14. Epub 2019 Feb 14.

Klinik für Urologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland.

Urologe A 2019 Jan 28. Epub 2019 Jan 28.

Klinik für Urologie der Universität Regensburg am Caritas-Krankenhaus St. Josef, Landshuter Str. 65, 93053, Regensburg, Deutschland.

Urologe A 2019 Jan;58(1):65-76

Urologische Klinik und Poliklinik, Klinikum der Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

Postoperative follow-up care after curative surgery or ablative treatment is the standard of care in patients with nonmetastatic renal cell carcinoma. The goal is to identify and treat postoperative complications and local recurrences early on. Follow-up investigations and their relevance are widely acknowledged and validated and patients undergoing follow-up seem to benefit from a longer survival in nonmetastatic renal cell carcinoma. Read More

Urologe A 2019 Jan 8. Epub 2019 Jan 8.

Institut für Didaktik und Ausbildungsforschung in der Medizin, Klinikum der LMU München, München, Deutschland.

Background And Objectives: The rapid development of new knowledge resources is essential for continuous training and continuing education. Since the training period often coincides with the starting of a family, time resources are often scarce. For this reason, a new, voluntary, web-based e‑learning training series was designed for urological assistants (urology onLINE). Read More

Urologe A 2019 Jan;58(1):5-13

Klinik und Poliklinik für Radiologie, Klinikum der Universität München, Campus Großhadern, München, Deutschland.

Background: Staging of bladder cancer, hematuria as well as the evaluation of unclear findings of the kidneys and ureters are the most frequent indications for imaging of the upper urinary tract (UUT). Endourological assessment of the UUT is much more invasive compared to imaging of the bladder, raising the question of the optimal imaging technique. Several technical improvements regarding computed tomography (CT) as well as magnetic resonance imaging (MRI) were implemented in recent years. Read More

Urologe A 2019 Jan;58(1):64

Museum, Bibliothek und Archiv der Deutschen Gesellschaft für Urologie, Düsseldorf, Deutschland.

Urologe A 2018 Dec 19. Epub 2018 Dec 19.

Klink für Urologie und Urologische Onkologie der Medizinischen Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

Knowledge of artificial intelligence will become essential in urology and medicine in the future. Today, computer-aided solutions are used for higher-dimensioned data or complex questions. In urological research, but also in clinical application, artificial neural networks (ANN) have been increasingly used for years and are continuously being developed. Read More

Urologe A 2018 Dec 12. Epub 2018 Dec 12.

Klinik für Urologie und Kinderurologie, Universitätsklinik Ulm, Prittwitzstr. 43, 89075, Ulm, Deutschland.

Background And Objectives: The development of child day care is currently the focus of a public discussion. More and more very young children are cared for in a day-care facility rather than by the family. Therefore, key aspects of education are shifted into these institutions. Read More

Urologe A 2018 Dec;57(12):1431-1432

Berufsverband der Deutschen Urologen e. V., Sylt OT Keitum, Deutschland.

Urologe A 2018 Dec;57(12):1445-1451

Frauenklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Str. 22, 81765, München, Deutschland.

Background: Benign, premalignant and malignant changes in the anogenital region, as in the oropharynx are often affected by a persistent HPV infection. Since a causal therapy isn't possible, the focus is on early diagnosis of dysplasia. Better knowledge of the human papilloma virus led to the development of the HPV vaccine and now primary prevention of cancer is possible. Read More

Urologe A 2018 Nov;57(11):1346-1350

Fachgebiet Impfprävention, Robert Koch-Institut, Berlin, Deutschland.

Urologe A 2018 Nov;57(11):1375-1388

Abteilung für Neuro-Urologie, Marien Hospital Herne, Universitätsklinikum der Ruhr-Universität Bochum, Hölkeskampring 40, 44625, Herne, Deutschland.

Sacral neuromodulation (SNM) is a minimally invasive, established treatment modality for overactive bladder (OAB) as well as for other pelvic functional disorders, such as non-obstructive urinary retention and fecal incontinence. A pacemaker implanted in the upper buttocks delivers mild electrical pulses to the sacral nerves thereby modulating pathological afferent signals from pelvic end organs. The current article conveys the current knowledge on the indications, contraindications, mechanism of action, implantation technique, efficacy and complications of SNM for the treatment refractory OAB. Read More

Urologe A 2018 Sep 14. Epub 2018 Sep 14.

Klinik für Urologie und Kinderurologie, St. Antonius-Hospital, Akademisches Lehrkrankenhaus der RWTH Aachen, Dechant-Deckers-Straße 8, 52249, Eschweiler, Deutschland.

Urologe A 2018 Dec;57(12):1452-1456

Urologische Klinik, Klinikum Memmingen, Lehrkrankenhaus der LMU München, Bismarckstraße 23, 87700, Memmingen, Deutschland.

Due to the lack of an established school-based immunization program, the initial German public funded girls-only human papillomavirus (HPV)-vaccination strategy failed. Over the last decade, the female coverage rates have not exceeded much more than 40%, thus, missing herd immunity for boys. Therefore, the German HPV immunization program has been revised and currently recommends a gender-neutral HPV vaccination for all children aged 9-14 years to prevent all HPV-related tumors which can be prevented by immunization. Read More

Urologe A 2018 Sep 3. Epub 2018 Sep 3.

Klinikum, Lehrstuhl für Urologie, Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

In a performance- and success-oriented profession like that of physicians, especially in an academic environment, a certain balance seems indispensable. In the past and today, recreational activities of physicians are very diverse. In addition to sports activities, musical and cultural interests have always been and still are widespread among physicians. Read More

Urologe A 2018 Oct;57(10):1185-1190

Klinik für Kinderurologie in Kooperation mit der Universität Regensburg, KUNO-Kinderkliniken Regensburg, Regensburg, Deutschland.

In recent years, the number of refugees to Germany has risen dramatically. Nearly half of the refugees are under 18, and a large percentage of them have acute or chronic medical problems. This situation poses a unique challenge to pediatric hospitals. Read More

Urologe A 2018 Oct;57(10):1191-1199

Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg - Standort Gießen, Gießen, Deutschland.

We are observing the largest worldwide wave of migration ever. Displaced persons usually do not have access to general health care and are faced with a lack of hygienic conditions and infection control while fleeing, which leads to an accumulation of "exotic" infectious diseases. The number of patients with tuberculosis (TB) had declined for many years in Germany; however, increasing numbers of cases have recently been observed. Read More

Urologe A 2018 Oct;57(10):1208-1213

Klinik für Urologie und Kinderurologie, St.-Antonius-Hospital Eschweiler, Akademisches Lehrkrankenhaus der RWTH Aachen, Dechant-Deckers-Straße 8, 52249, Eschweiler, Deutschland.

Background: Because sick and injured children from war and crisis areas can often only be helped to a limited extent in their countries of origin, those children with the most complex diseases often receive medical treatment in Europe.

Materials And Methods: To evaluate the postoperative outcome of reconstructive interventions in children from war and crisis areas, an evaluation of the clinic's internal database between 1997 and 2017 was carried out. The operative indication, the surgical procedure, any revisions or conversions and the overall mortality were analyzed. Read More

Urologe A 2018 Nov;57(11):1362-1365

Institut für Geschichte der Medizin der Robert Bosch Stiftung, Straußweg 17, 70184, Stuttgart, Deutschland.

Modern sexology was introduced by the Berlin-based Magnus Hirschfeld, who was born 150 years ago. He revolutionized the physician-patient relationship by introducing new terms of sexual behavior. His theory of "sexual in-betweens" paved the way for new concepts in sexual therapy, including hormonal pills in urological practice. Read More

Urologe A 2018 08;57(8):891-892

Berufsverband der Deutschen Urologen e. V., Haart 87-89, 24534, Neumünster, Deutschland.

Urologe A 2018 Sep;57(9):1103-1110

Institut für Geschichte, Theorie und Ethik der Medizin, Medizinische Fakultät, Heinrich-Heine-Universität, Düsseldorf, Deutschland.

In this contribution we describe the life and work of the Berlin physician Carl Posner (1854-1928). We present his central role as a member of the founding generation of urology, andrology, and academic sexology in Germany. His clinical work, research and publication illustrate the central role these new disciplines played in the urological field. Read More

Urologe A 2018 Sep;57(9):1048-1057

Klinik für Urologie der Universität Regensburg, Caritas-Krankenhaus St. Josef, Landshuter Straße 65, 93053, Regensburg, Deutschland.

The recent introduction of new diagnostic techniques has revolutionized uro-oncolgy. In addition to multiparametric magnetic resonance imaging (mpMRI), prostate-specific membrane antigen positron-emission tomography (PSMA-PET) plays an increasingly import role in daily practice. The introduction of three-dimensional (3D) printing technologies in the context of robot-assisted uro-oncological surgery represents a first step towards individualized 3D imaging. Read More

Urologe A 2018 Aug;57(8):930-934

Zentralinstitut für die kassenärztliche Versorgung in der Bundesrepublik Deutschland, Salzufer 8, 10587, Berlin, Deutschland.

This article describes the economic situation in German outpatient practices of urology during the period 2012-2015 based on data from the Zi-Praxis-Panel (ZiPP). Additionally, it discusses the aspects of working times and operating times. Furthermore, the article presents a new Zi project in the field of day surgery and ambulant inpatient surgery. Read More

Urologe A 2018 Sep;57(9):1111-1132

Curator Deutsche Gesellschaft für Urologie e. V., Düsseldorf-Berlin, Deutschland.

The German Society of Urology was founded in 1906/1907 with a historical background starting in 1896 shortly after the death of Maximilian Nitze, the "inventor" of the cystoscope. This reflects the end of the first phase in the establishment of modern scientific urology as a specialty of its own within German-speaking countries (Imperial Germany, the Austria-Hungary Empire and Switzerland). Supported by German emigrants, the international orientation of German urology and networks was important during this time period. Read More

Urologe A 2018 Sep;57(9):1075-1090

Urologische Klinik, Universität Ulm, Ulm, Deutschland.

The monopoly of robotic surgical devices of the last 15 years will end in 2019 when key patents of Intuitive Surgical expire. Thus, we can expect an interesting competitive situation in the coming years. Based on personal experience with robot-assisted surgery since 2001, we conducted a search of the current literature together with a search of relevant patents in this field. Read More

Urologe A 2018 Jul 12. Epub 2018 Jul 12.

BvDU Berufsverband der Deutschen Urologen e. V., Nestorstr. 8-9/4, Berlin, 10709, Deutschland.

The Professional Association of German Urologists (BvDU e. V) and Deutsches Institut für Fachärztliche Versorgungsforschung GmbH (DIFA) jointly develop the online portals urogister.de and uroscience. Read More

Urologe A 2018 Aug;57(8):954-957

Akademisches Lehrkrankenhaus der RWTH Aachen, Klinik für Urologie und Kinderurologie, St.-Antonius-Hospital, Dechant-Deckers-Str. 8, 52249, Eschweiler, Deutschland.

Urologe A 2018 Aug;57(8):927-929

Geschäftsstelle des Sachverständigenrates zur Begutachtung der Entwicklung im Gesundheitswesen, Friedrichstraße 108, 10117, Berlin, Deutschland.

Urologe A 2018 Jun 11. Epub 2018 Jun 11.

Promotionskolleg KoMMa.G, TU Braunschweig - Abteilung für Geschichte der Naturwissenschaften mit Schwerpunkt Pharmaziegeschichte, Beethovenstr. 55, 38106, Braunschweig, Deutschland.

Within the field of the history of technology, much has been written about the so-called "prosthesis boom" of the First World War. Most of these studies claim that the main motive of the mass supply of artificial limbs to amputee soldiers was primarily aimed at restoring the work force. However, because these studies often lack a gender perspective, it stays unmentioned to what extent this also served to reconstruct a hegemonic masculinity that had become fragile, if not destroyed by the consequences of the war. Read More

Urologe A 2018 Jul;57(7):836-845

Institut für Geschichte, Theorie und Ethik der Medizin, Heinrich-Heine-Universität, Düsseldorf, Deutschland.

The use of eponyms has a long history in medicine. But it is a rare case that a term not associated with a procedure or an anatomical description has come into use. The terms "stent" and "splint" in German and English used as a verb and a noun are a typical example. Read More

Urologe A 2018 07;57(7):852-854

Endourologie, Klinik für Urologie, Uro-Onkologie, spezielle urologische und roboter-assistierte Chirurgie, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Urologe A 2018 Jun;57(6):655-656

Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität in München, Klinikum Großhadern, LMU, Marchioninistr. 15, 81377, München, Deutschland.

Urologe A 2018 Jul;57(7):813-820

Klinik für Urologie, Uro-Onkologie, Roboter-assistierte und Spezielle Urologische Chirurgie, Universitätsklinikum Köln, Köln, Deutschland.

In March 2017 the 'Advanced Prostate Cancer Consensus Conference' (APCCC) took place in St. Gallen (Switzerland). The APCCC-panelists are internationally well known experts. Read More

Urologe A 2018 Jul;57(7):798-803

Solidaris Rechtsanwaltsgesellschaft mbH, Von-der-Wettern-Straße 11, 51149, Köln, Deutschland.

Background: This article describes the introduction of the law to combat corruption in the healthcare system.

Objective: The effects of the introduced penal regulations on the delivery of medical services is critically scrutinized and the associated procedures as well as indications for the course of action are presented.

Results: Knowledge of the relevant regulations and types of procedure is decisive for the penal, social legislative and professional conduct risk minimization. Read More

Urologe A 2018 Jul;57(7):804-810

Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo), Ardeystr. 67, 44139, Dortmund, Deutschland.

Convincing urological expert opinions require the objectification of medical history complaints of health and functional disorders in the legal sense of obtaining full proof. This means that there is such a high degree of likelihood, beyond any doubt of a reasonable person observing the condition (Bundessozialgericht Entscheidung [BSGE] 32, 203/207). This requires a comprehensive general and special medical history survey, as well as a series of urological examination procedures in the hands of experienced urologists. Read More

Urologe A 2018 May;57(5):530-531

Klinik für Anästhesiologie , Überregionales Zentrum für Schmerztherapie und Palliativmedizin , Universitäre Palliativmedizin Krhs. St. Vincentius, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 131, 69120, Heidelberg, Deutschland.

Urologe A 2018 May 3. Epub 2018 May 3.

Springer Medizin Verlag GmbH, Tiergartenstr. 17, 69121, Heidelberg, Deutschland.

Urologe A 2018 Oct;57(10):1222-1229

Klinik für Urologie und Kinderurologie, St. Antonius-Hospital, Akademisches Lehrkrankenhaus der RWTH Aachen, Dechant-Deckers-Straße 8, 52249, Eschweiler, Deutschland.

Background: Early detection examinations take place from birth to the age of 6 years. The youth screening is a continuation of the screening of the "U-series" and should be carried out between the age of 12-15 and 16-17, respectively. Afterwards adolescent girls have good contact with a gynecologist, but adolescent boys usually do not have a medical contact person who they can trust in. Read More

Urologe A 2018 Jun;57(6):709-713

Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland.

In the last 3 years, Lutetium-177 prostate-specific membrane antigen radioligand therapy (Lu-177-PSMA-RLT) has received increasing attention in nuclear medicine as a new form of treatment for castration-resistant metastatic prostate cancer. This therapy combines the radionuclide Lutetium-177, which has been therapeutically used in nuclear medicine for many years, with a molecular target of the transmembrane prostate-specific membrane antigen expressed by prostate cancer cells. Since there are no prospective randomized studies on Lu-177-PSMA-RLT and the question of reimbursement has repeatedly been the subject of review by the MDK Nordrhein (Medischenische Dienst der Krankenversicherung), there was a desire because of the increasing number of patients being treated to clarify under which circumstances Lu-177-PSMA-RLT can be reimbursed by German statutory health insurance. Read More

Urologe A 2018 Jun;57(6):686-692

Urologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.

In November 2016, the results of a phase III clinical trial with the protein cell death (PD)-1 inhibitor pembrolizumab for second-line treatment of metastatic urothelial carcinoma were published and showed an overall survival benefit in comparison with conventional chemotherapy with vinflunine, docetaxel, or paclitaxel. In a similar trial the PD-L1 antibody atezolizumab showed no significant benefit in comparison to chemotherapy in the subgroup of PD-L1-positive patients and, thus, missed its primary endpoint. For other PD-1/PD-L1 directed substances, large phase I/II trials reported data concerning response rates and overall survival. Read More

Urologe A 2018 May;57(5):607-608

Klinik und Poliklinik für Urologie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, München, Deutschland.

Urologe A 2018 May;57(5):594-600

Institut für Geschichte der Medizin, Robert Bosch Stiftung, Straußweg 17, 70184, Stuttgart, Deutschland.

Disorders of the lower abdomen were often associated with sexually transmitted diseases (STDs) or related conditions. The urological diagnostic workup and treatment was based on the idea that technical devices and objective scientific examination methods would lead to targeted success. The fact that illnesses such as urinary retention, urinary incontinence, urge incontinence, orchitis or urethritis often implicated psychosomatic complications and had a possibly far more important impact on sexual life did not play a role in the early years of urology. Read More

Urologe A 2018 May;57(5):532-542

Urologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

The chemotherapy-induced nausea and vomiting (CINV) is one of the most frequent side effects in cytostatic therapy and a profound challenge during the therapy of cancer patients. Therefore, standardized guideline-orientated prophylaxis is essential and a fundamental contribution for the success of treatment. This review summarizes the current recommendations for CINV of the Multinational Association of Supportive Care in Cancer (MASCC) and European Society of Medical Oncology (ESMO), the American Society for Clinical Oncology (ASCO), the National Comprehensive Cancer Network (NCCN) and the S3-guideline Supportive Therapie of the Leitlinienprogramm Onkologie and shall facilitate its use in the daily routine. Read More

Urologe A 2018 May;57(5):583-590

Klinik für Urologie und Kinderurologie, Universitätsmedizin Mainz, Mainz, Deutschland.

Improved understanding of the immunomodulatory interactions between tumor cells and immune cells has led to new and promising systemic therapeutic approaches in the first- and second-line therapy of urological tumors. Particularly in the case of urothelial carcinoma, for the first time in 20 years, checkpoint inhibitors (PD-1 and PDL-1 inhibitors) provide well-tolerated therapy that achieves response rates of >20% that can be sustained over the long term. This review explains the approach of immunotherapy and summarizes the current phase III clinical situation on urothelial carcinoma and renal cell carcinoma. Read More

Urologe A 2018 Apr;57(4):389

Klinik Quellental, Bad Wildungen, Deutschland.

Urologe A 2018 Apr;57(4):463-473

Abteilung für Urologie, Asklepios Klinik Barmbek, Hamburg, Deutschland.

Interventional treatment of stones essentially consists of three treatment modalities. Extracorporeal shockwave lithotripsy (ESWL), in addition to uterorenoscopy (URS) and percutaneous nephrolitholapaxy (PCNL) is an essential treatment pillar and is the only noninvasive therapy option for the treatment of urinary stones. After a long period of ESWL being the leading choice in stone treatment, the number of SWL interventions diminished in recent years in favor of the other two treatment modalities (URS and PCNL). Read More

Urologe A 2018 Apr;57(4):413-417

Klinikum der Universität München, Großhadern, München, Deutschland.

Two major pathways of penile carcinogenesis are known: human papillomavirus (HPV)-induced penile cancer and HPV-negative cancers associated with chronic dermatoses. Therefore, modern measures for prevention of penile cancer may for example include prophylactic HPV vaccination. The resulting B‑cell-mediated immunity to HPV capsid proteins is effective protection against future HPV infections. Read More

Urologe A 2018 Mar;57(3):323-326

Urologische Klinik Großhadern, Klinikum der Universität München, München, Deutschland.

Urologe A 2018 Mar;57(3):274-279

Urologische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland.

Background: The incidence of small renal masses has been rising over the last few decades. At the same time, mortality of renal cell carcinoma (RCC) is decreasing. These trends can be explained by the availability of improved therapeutic measures and the good prognosis of small renal masses (SRM) turning out to be histopathologically benign or of low malignancy in many cases. Read More

Urologe A 2018 Apr;57(4):453-457

Klinikum der Universität München, Großhadern, Deutschland.

Anogenital warts are the most frequently sexually transmitted disease caused by viral infections worldwide. People's lifetime risk to suffer from this disease or HPV-associated precancers counts to more than 10%. The therapy and the recurrence rates of both disorders continue to be challenging in Germany because the coverage rate of the preventive HPV vaccination is still insufficient. Read More