505,860 results match your criteria Depression

Trauma exposure and co-occurring ICD-11 post-traumatic stress disorder and complex post-traumatic stress disorder in adults with lived experience of psychiatric disorder.

Acta Psychiatr Scand 2022 Jun 26. Epub 2022 Jun 26.

National Centre for Mental Health, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, Wales.

Objective: To establish factors associated with ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD) in a large sample of adults with lived experience of psychiatric disorder and examine the psychiatric burden associated with the two disorders.

Methods: 1305 adults were recruited from the National Centre for Mental Health (NCMH) cohort. ICD-11 PTSD/CPTSD were assessed with the International Trauma Questionnaire (ITQ). Read More

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A direct referencing method of the tibial plateau for the posterior tibial slope in medial unicompartmental knee arthroplasty.

J Orthop Surg Res 2022 Jun 25;17(1):329. Epub 2022 Jun 25.

Department of Orthopaedic Surgery, Kindai University Hospital, 377-2 Ohno-Higashi, Osaka-Sayama City, Osaka, 589-8511, Japan.

Purpose: There is no consensus on intraoperative references for the posterior tibial slope (PTS) in medial unicompartmental knee arthroplasty (UKA). An arthroscopic hook probe placed on the medial second quarter of the medial tibial plateau (MTP) in an anteroposterior direction may be used as a direct anatomical reference for the PTS. The purpose of this study is to investigate the availability and accuracy of this method. Read More

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Time and gender measurement invariance in the modified Calderon depression scale.

Health Qual Life Outcomes 2022 Jun 25;20(1):100. Epub 2022 Jun 25.

Instituto de Investigaciones Para El Desarrollo Con Equidad (EQUIDE), Universidad Iberoamericana, Mexico City, Mexico.

Background: Assessing change and comparing groups requires high quality and invariant scales. However, there is limited evidence of simultaneous longitudinal and gender measurement invariance for depression scales. This evidence is even more scant with long-established panel studies from low and middle-income countries. Read More

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Evaluation of cognitive, mental, and sleep patterns of post-acute COVID-19 patients and their correlation with thorax CT.

Acta Neurol Belg 2022 Jun 26. Epub 2022 Jun 26.

Pulmonology Department, Kayseri City Hospital, Kayseri, Turkey.

Objective: In this study, we have evaluated the cognitive, mental, and sleep patterns of post-COVID patients 2 months after their hospitalization, and after scoring their hospitalization thorax CTs, we have compared the degree of the lung involvement with cognitive and mental states of the patients.

Materials And Methods: Forty post-COVID patients were included in our study. Patients who were hospitalized due to COVID-19 and who had thorax CT scan at the admission were included in the study. Read More

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Religiosity, Religious Coping and Distress Among Outpatients with Psychosis in Singapore.

J Relig Health 2022 Jun 25. Epub 2022 Jun 25.

Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore, 539747, Singapore.

This study aimed to investigate the prevalence of religious coping and explore the association between religious coping, religiosity, and distress symptoms amongst 364 outpatients diagnosed with psychosis in Singapore. Positive and Negative Religious Coping (PRC and NRC), religiosity (measuring the constructs of Organised Religious Activity (ORA), Non-Organised Religious Activity (NORA), and Intrinsic Religiosity (IR)) and severity of distress symptoms (depression, anxiety and stress) were self-reported by the participants. The majority of participants (68. Read More

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Investigating the association between infertility and psychological distress using Australian Longitudinal Study on Women's Health (ALSWH).

Sci Rep 2022 Jun 25;12(1):10808. Epub 2022 Jun 25.

College of Health, Medicine and Wellbeing, The University of Newcastle (UON), University Drive, Callaghan, NSW, 2308, Australia.

Infertility affects millions of people globally. Although an estimated 1 in 6 couples in Australia are unable to conceive without medical intervention, little is known about the mental health impacts of infertility. This study investigated how infertility impacts the mental health of women. Read More

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A single-cell survey unveils cellular heterogeneity and sensitive responses in mouse cortices induced by oral exposure to triphenyl phosphate.

Arch Toxicol 2022 Jun 25. Epub 2022 Jun 25.

Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Toxicology, School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan Rd. 2, Guangzhou, 510080, China.

Triphenyl phosphate (TPhP) is a non-halogenated organophosphorus flame retardant, and there is a higher exposure risk in children. TPhP has been found to be neurotoxic upon developmental exposure, yet the specific mechanism remains unclear. To characterize the cellular responses underlying TPhP-induced developmental neurotoxicity, we administered TPhP (0. Read More

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Cardiopulmonary predictors of mortality in patients with COVID-19: What are the findings?

Arch Cardiovasc Dis 2022 Jun 8. Epub 2022 Jun 8.

Advanced Thoracic Research Centre, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Since 2019, coronavirus disease 2019 (COVID-19) has been the leading cause of mortality worldwide.

Aims: To determine independent predictors of mortality in COVID-19, and identify any associations between pulmonary disease severity and cardiac involvement.

Methods: Clinical, laboratory, electrocardiography and computed tomography (CT) imaging data were collected from 389 consecutive patients with COVID-19. Read More

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Sexual Function and Mood Disorders Among Menopausal Women: A Systematic Scoping Review.

J Sex Med 2022 Jul;19(7):1098-1115

Department of Obstetrics and Gynecology, University Hospitals Schleswig-Holstein, Kiel, Germany.

Background: Changes in sex hormones during menopause may have detrimental effects on a woman's sexual function and cause mood disorders. The treatment of both conditions is a challenge in gynecology.

Aim: To review the published literature on sexual function and mood disorders among peri- and postmenopausal women. Read More

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Aging in bipolar disorder: Cognitive performance and clinical factors based on an adulthood-lifespan perspective.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic of Barcelona, IDIBAPS, CIBERSAM, University of Barcelona, Barcelona, Catalonia, Spain.

Background: The evolution of cognitive performance throughout the lifespan in bipolar disorder (BD) is understudied. This cross-sectional study aims to describe the cognitive performance across age groups.

Methods: A sample of 654 participants was recruited for this study (BD = 432 and healthy controls -HC- =222). Read More

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The interaction of P11 methylation and early-life stress impacts the antidepressant response in patients with major depressive disorder.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, PR China; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Southeast university, Nanjing 210009, PR China. Electronic address:

Purpose: The present research investigates the influence of P11 gene DNA methylation combined with life stress on the response to antidepressants in the first two weeks.

Methods: A total of 291 Han Chinese patients with major depressive disorder and 100 healthy controls were included. The Life Events Scale and the Childhood Trauma Questionnaire were used to assess stress. Read More

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Correlation between cognitive deficits and dorsolateral prefrontal cortex functional connectivity in first-episode depression.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China. Electronic address:

Introduction: Although depression is commonly accompanied by cognitive deficits, the underlying mechanism remains unclear. One possibility is that such deficits are related to abnormal brain network connections. The purpose of this study was thus to investigate changes in brain functional connectivity (FC) in depression and its relationship with cognitive deficits. Read More

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Sleep and affective disorders in relation to Parkinson's disease risk among older women from the Women's Health Initiative.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIA/NIH/IRP, Baltimore, MD 21225, USA.

Objectives: To evaluate sleep and affective (mood/anxiety) disorders as clinical predictors of incident Parkinson's disease (PD) among women ≥65 years of age.

Methods: We performed secondary analyses with available data from the Women's Health Initiative Clinical Trials and Observational Study linked to Medicare claims. Sleep, mood and anxiety disorders at baseline were defined using diagnostic codes. Read More

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Effect of intervention delivered by lay maternal care providers to improve outcome and parenting skills among adolescents with perinatal depression in Nigeria (the RAPiD study): A cluster randomized controlled trial.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Lady Davis Institute, Jewish General Hospital, Montreal, Canada.

Background: Perinatal depression is more common and is associated with greater negative consequences among adolescents than adults. Psychosocial interventions designed for adults may be inadequate at addressing the unique features of adolescent perinatal depression.

Methods: In a two-arm parallel cluster randomized trial conducted in thirty primary maternal care clinics in Ibadan, Nigeria (15-intervention and 15-control) we compared age-appropriate intervention consisting of problem-solving therapy, behavioral activation, parenting skills training, and parenting support from a self-identified adult to care as usual. Read More

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A novel machine learning approach to shorten depression risk assessment for convenient uses.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Beijing Anding Hospital, China; University of Toronto, Canada. Electronic address:

Background: Depression is a mental disorder affecting many people worldwide which has been exacerbated by the current pandemic. There is an urgent need for a reliable yet short scale for individuals to self-assess the risk of depression conveniently and rapidly on a regular basis.

Methods: We obtained a dataset of responses to the Depression, Anxiety, and Stress questionnaire (DASS-42) from a large sample of individuals worldwide (N = 31,715). Read More

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Multi-centre classification of functional neurological disorders based on resting-state functional connectivity.

Neuroimage Clin 2022 Jun 17;35:103090. Epub 2022 Jun 17.

Psychosomatic Medicine, Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

Background: Patients suffering from functional neurological disorder (FND) experience disabling neurological symptoms not caused by an underlying classical neurological disease (such as stroke or multiple sclerosis). The diagnosis is made based on reliable positive clinical signs, but clinicians often require additional time- and cost consuming medical tests and examinations. Resting-state functional connectivity (RS FC) showed its potential as an imaging-based adjunctive biomarker to help distinguish patients from healthy controls and could represent a "rule-in" procedure to assist in the diagnostic process. Read More

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NUCB2/nesfatin-1 is associated with severity of eating disorder symptoms in female patients with obesity.

Psychoneuroendocrinology 2022 Jun 17;143:105842. Epub 2022 Jun 17.

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany; Charité Center for Internal Medicine and Dermatology, Department of Psychosomatic Medicine, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany; Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany. Electronic address:

Background: Nesfatin-1 has been described as an anorexigenic peptide. Comprehensive evidence also points towards an involvement of nesfatin-1 in the modulation of emotional pathways with a sex-specific regulation of nesfatin-1 in association with anxiety. Although the implication of nesfatin-1 in the regulation of food intake is well-established in animals, data in humans are lacking. Read More

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Major depression precedes the first clinical manifestation of brain small vessel disease.

Psychiatry Res 2022 Jun 12;314:114681. Epub 2022 Jun 12.

3rd Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.

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Efficacy and Safety of the Bushen-Shugan Method in Pregnancy Outcomes in Patients with Recurrent Miscarriage Complicated by Anxiety and Depression: A Prospective Randomized Trial.

Altern Ther Health Med 2022 Jun 24. Epub 2022 Jun 24.

Objective: This study aimed to investigate the effect of the Bushen-Shugan (BSSG) method on pregnancy outcomes, serum D-dimer (D-D), platelet aggregation rate, homocysteine (Hcy) and antithrombin III (AT-III) in patients with recurrent miscarriage complicated by anxiety and depression.

Methods: From December 2016 to December 2019, 100 patients with recurrent miscarriage combined with anxiety and depression were enrolled in our study, and a prospective randomized trial was carried out. Patients were randomly assigned to either the control group or the BSSG group via the random number table method. Read More

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Effects of Assistive Technology Application in Dementia Intervention for People with Mild Cognitive Impairment & Mild Alzheimer Type Dementia and Caregiver.

Altern Ther Health Med 2022 Jun 24. Epub 2022 Jun 24.

Background: Dementia, a degenerative disease, requires alternative treatment to maintain function, but previous studies suggest only the therapeutic effect of a temporary program.

Primary Study Objective: The current study aimed to examine the effects of assistive technologies on cognitive function, daily living ability, and psychosocial symptoms in elderlies with mild cognitive impairment, elderlies with mild dementia and their caregivers.

Design: The research team designed an experimental study that used application as the intervention. Read More

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An Integrative Review of Community-Based Mental Health Interventions Among Resettled Refugees from Muslim-Majority Countries.

Community Ment Health J 2022 Jun 25. Epub 2022 Jun 25.

Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, 10920 Wilshire Blvd., Suite 300, Los Angeles, CA, 90024, USA.

Resettled refugees from Muslim-majority countries are underrepresented in research and meeting their mental health needs remains a challenge for countries of resettlement. In this integrative review, we synthesize community-based mental health interventions using an ecological framework. Eleven relevant studies were identified using PubMed and PsychInfo database. Read More

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Measurement properties of the Dutch PROMIS-29 v2.1 profile in people with and without chronic conditions.

Qual Life Res 2022 Jun 25. Epub 2022 Jun 25.

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, de Boelelaan 1089a, 1081 HV, Amsterdam, The Netherlands.

Purpose: To investigate the structural validity, internal consistency, measurement invariance, and construct validity of the Dutch PROMIS-29 v2.1 profile, including seven physical (e.g. Read More

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A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment.

Curr Atheroscler Rep 2022 Jun 25. Epub 2022 Jun 25.

Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.

Purpose Of Review: Sex and gender differences exist with regard to the association between depression and cardiovascular disease (CVD). This narrative review describes the prevalence, mechanisms of action, and management of depression and CVD among women, with a particular focus on coronary heart disease (CHD).

Recent Findings: Women versus men with incident and established CHD have a greater prevalence of depression. Read More

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Alteration of interoceptive sensitivity: expanding the spectrum of behavioural disorders in amyotrophic lateral sclerosis.

Neurol Sci 2022 Jun 25. Epub 2022 Jun 25.

Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Via Sergio Pansini, 5, 80131, Naples, Italy.

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with progressive loss of upper and lower motor neurons. Non-motor-symptoms, such as cognitive, emotional, autonomic, and somatosensory alterations, have been also described. Interoception represents the link between the body and brain, since it refers to the ability to consciously perceive the physical condition of the inner body, including one's heartbeat (i. Read More

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Systematic review exploring the relationship between sexual abuse and lower urinary tract symptoms.

Int Urogynecol J 2022 Jun 25. Epub 2022 Jun 25.

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Introduction And Hypothesis: Patients presenting with lower urinary tract symptoms (LUTS) may report a history of sexual abuse (SA), and survivors of SA may report LUTS; however, the nature of the relationship is poorly understood. The aim of this review is to systematically evaluate studies that explore LUT dysfunction in survivors of SA.

Methods: A systematic literature search of six databases, Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, CINAHL, AMED, and PsycINFO, was performed. Read More

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Endometriosis and inflammatory immune responses: Indian experience.

Rahul K Gajbhiye

Am J Reprod Immunol 2022 Jun 25. Epub 2022 Jun 25.

Clinical Research Laboratory, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai, 400012, India.

Endometriosis is a public health disorder affecting ∼ 247 million women globally and ∼ 42 million women in India. Women with endometriosis suffer from dysmenorrhea, chronic pelvic pain, dyspareunia, dyschezia, fatigue, depression, and infertility leading to significant socioeconomic impact and morbidity. The etiology of endometriosis is not understood even after 100 years of research. Read More

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Depression and anxiety in colorectal cancer patients: TIES TO PAIN, FATIGUE, AND INFLAMMATION.

Psychooncology 2022 Jun 25. Epub 2022 Jun 25.

Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH, USA.

Objective: Colorectal cancer poses a significant threat to both psychological and physical health. This study examined relationships between anxiety and depressive symptoms with pain, fatigue, and inflammation among colorectal patients.

Methods: Colorectal cancer patients (n = 88, stages 0-IV) completed a laboratory-based study visit before undergoing adjuvant cancer treatment. Read More

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The prevalence of anxiety and depression in patients with ostomy: A systematic review and meta-analysis Short title: The prevalence of anxiety and depression in ostomy.

Psychooncology 2022 Jun 25. Epub 2022 Jun 25.

Nursing Care Research Center (NCRC), School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.

Aim: The prevalence of anxiety and depression in patients with ostomy is reported differently. The aim of this systematic review and meta-analysis is to estimate the global prevalence of anxiety and depression in patients with ostomy.

Method: A systematic search of Embase, Proquest, Scopus, PubMed and Web of Science (ISI) databases was conducted from January 1990 up to May 5th, 2021. Read More

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