1,551 results match your criteria Denture Stomatitis


Antimicrobial and protective effects of non-thermal plasma treatments on the performance of a resinous liner.

Arch Oral Biol 2020 Jun 20;117:104822. Epub 2020 Jun 20.

Department of Prosthodontics and Periodontology, University of Campinas (UNICAMP), Piracicaba Dental School, Piracicaba, Brazil. Electronic address:

Objective: Overcoming substantial shortcomings of soft liners as physico-chemical changes and liner-biofilm-related infections remains a challenge in the rehabilitation treatment. In this study, protective non-thermal plasma (NTP) treatments were developed on the soft liner surface to improve its surface and physico-chemical properties and to reduce fungal colonization after biofilm inhibition challenge.

Methods: Resinous liner specimens (Coe-Soft) were prepared and distributed in 3 groups according to the surface treatments: (1) untreated (control); (2) treated with sulfur hexafluoride-based NTP (SF); and (3) treated with hexamethyldisiloxane-based NTP (HMDSO). Read More

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http://dx.doi.org/10.1016/j.archoralbio.2020.104822DOI Listing

Antifungal activity of Punicalagin - nystatin combinations against Candida albicans.

Oral Dis 2020 Jun 24. Epub 2020 Jun 24.

Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo (USP), Alameda Dr. Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, Brazil.

Objectives: Oral candidiasis is the most common opportunistic fungal infection of oral mucosa and results from an overgrowth of Candida, especially Candida albicans. The potential anti-C. albicans and cytotoxicity of punicalagin (PCG), isolated from Punica granatum, alone or with nystatin (NYS) were evaluated. Read More

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http://dx.doi.org/10.1111/odi.13507DOI Listing

Suppressive effects of 2-methacryloyloxyethyl phosphorylcholine (MPC)-polymer on the adherence of species and MRSA to acrylic denture resin.

Heliyon 2020 Jun 16;6(6):e04211. Epub 2020 Jun 16.

Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8504, Japan.

Objectives: The effects of 2-methacryloyloxyethyl phosphorylcholine (MPC)-polymer on the adherence of microorganisms such as non- (NCAC) and methicillin-resistant (MRSA), frequently detected in oral infections in immunocompromised and/or elderly people, to denture resin material, are still unclear. Here, we report the effects of MPC-polymer on the adherence of , NCAC, and MRSA to acrylic denture resin.

Methods: Sixteen strains of seven strains of two strains of one strain of , and six strains of MRSA were used. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303995PMC

In vitro evaluation of physicochemical properties of soft lining resins after incorporation of chlorhexidine.

J Prosthet Dent 2020 Jun 12. Epub 2020 Jun 12.

Full Professor, Department of Prosthodontics, Rio de Janeiro State University, Rio de Janeiro, Brazil. Electronic address:

Statement Of Problem: Incorporating chlorhexidine into soft lining materials has been suggested to reduce biofilm development on the material surface and treat denture stomatitis. However, evaluation of the physicochemical properties of this material is necessary.

Purpose: The purpose of this in vitro study was to evaluate the physicochemical properties of resin-based denture soft lining materials modified with chlorhexidine diacetate (CDA). Read More

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http://dx.doi.org/10.1016/j.prosdent.2020.03.027DOI Listing

[Clinical analysis of denture-related oral mucosal lesions in 185 patients with removable denture].

Shanghai Kou Qiang Yi Xue 2020 Feb;29(1):85-88

Department of Stomatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China. Chengdu 610091, Sichuan Province, China.

Purpose: To investigate the category and prevalence rate of denture-related oral mucosal lesions (DML) in 185 patients with removable denture and analyze the influencing factors.

Methods: A total of 185 patients with removable denture who visited the department of stomatology of our hospital from October 2015 to June 2018 were investigated by questionnaire. DML types and locations were recorded in detail, and patients were followed up after treatment. Read More

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February 2020

The association between denture care and oral hygiene habits, oral hygiene knowledge and periodontal status of geriatric patients wearing removable partial dentures.

Eur Oral Res 2020 Jan;54(1):9-15

Private Periodontist, Istanbul Turkey.

Purpose: This study aims to evaluate the association of the denture care with oral hygiene habits, knowledge and periodontal status geriatric patients wearing removable partial denture (RPD) and to compare the relationship between denture cleaning and tooth brushing frequency.

Patients And Methods: In total, 553 participants wearing RPD for at least 6 months and aged 65-86 years were asked to complete a questionnaire following the clinical examination. Chisquare analysis and Fisher's exact test utilized to analyze the data. Read More

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http://dx.doi.org/10.26650/eor.20200048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252529PMC
January 2020

Denture-related stomatitis in new complete denture wearers and its association with Candida species colonization: a prospective case-series.

Quintessence Int 2020 ;51(7):554-565

Objectives: To assess the relationship between the development of denture-related stomatitis (DRS) and the identification of commonly isolated yeast species, and to evaluate various predisposing factors in Saudi participants wearing new removable dental prostheses.

Method And Materials: A total of 75 edentulous male participants were recruited, and 64 patients finished the present case-series. All participants received new conventional complete dentures. Read More

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http://dx.doi.org/10.3290/j.qi.a44630DOI Listing

Biocompatibility and Antimicrobial Activity of Extract for Dental Application.

Plants (Basel) 2020 May 26;9(6). Epub 2020 May 26.

Department of Dental Hygiene, Hanseo University, Chungcheongnam-do 31962, Korea.

This study was conducted to determine whether nature-derived extracts exhibit biocompatibility and antimicrobial effects against oral pathogens such as and . Fine particles of extract were used to probe for biocompatibility and antimicrobial activity toward these pathogens and results were evaluated with an MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay, spectrophotometric growth inhibitory assay, the total number of colony-forming units (CFU), an agar disk diffusion test, and scanning electron microscopy (SEM). In addition, UV/VIS spectroscopy was used to determine the levels of flavonoid and polyphenol in experimental solutions. Read More

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http://dx.doi.org/10.3390/plants9060670DOI Listing

Candida-Associated Denture Stomatitis and Murine Models: What Is the Importance and Scientific Evidence?

J Fungi (Basel) 2020 May 23;6(2). Epub 2020 May 23.

Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, Bauru, SP 17012-901, Brazil.

Considering the high prevalence and recurrence of Candida-associated denture stomatitis (CADS), in vivo studies in animal models are necessary before those in humans to evaluate new therapeutic strategies. This study aimed to review the literature on murine models of CADS induction using acrylic intraoral devices simulating dentures. Rats are recommended as experimental animals in these models as well as the adoption of a pasty diet. Read More

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http://dx.doi.org/10.3390/jof6020070DOI Listing

Evaluation of nanomaterials to prevent oral Candidiasis in PMMA based denture wearing patients. A systematic analysis.

J Oral Biol Craniofac Res 2020 Apr-Jun;10(2):189-193. Epub 2020 Apr 22.

Dept. of Applied Science & Humanities, Faculty of Engineering &Technology, Jamia Millia Islamia, New Delhi, India.

Purpose: The purpose of this study is the prevention of Candida colonies on PMMA Denture Base by altering the surface and incorporations of Nanoparticles.

Materials And Methods: The Pub Med/Medline was searched to identify 100 relevant studies published from 2011 to 2020. The search strategy employed the following keywords related to "use of Nanoparticles in dentistry", "Antimicrobial agents and PMMA", "Candidiasis and nanomaterials", "Prevention of oral Candidiasis", "Incorporation of antimicrobial agents in acrylic dentures," "nanoparticles as therapeutic agents for denture stomatitis", "Nanodentistry" or "Nanotechnology" or "Nanocomposite" or "Nanodrugs" or "Nanomaterials". Read More

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http://dx.doi.org/10.1016/j.jobcr.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193251PMC

Effect of Ultraviolet Radiation on Candida albicans Biofilm on Poly(methylmethacrylate) Resin.

J Prosthodont 2020 Apr 24. Epub 2020 Apr 24.

Department of Restorative Dentistry, College of Dentistry, UIC, Chicago, IL, USA.

Purpose: To investigate the effect of 254nm ultraviolet light on the viability of Candida albicans biofilm on poly(methylmethacrylate).

Methods: Poly(methylmethacrylate) specimens (1cm x 1cm x 1mm) were placed in 6-well culture plates. Each well contained 8ml of 10 colony forming units/milliliter of C. Read More

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http://dx.doi.org/10.1111/jopr.13180DOI Listing
April 2020
0.905 Impact Factor

Current perspectives and the future of Candida albicans-associated denture stomatitis treatment.

Dent Med Probl 2020 Jan-Mar;57(1):95-102

Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Denture stomatitis (DS) is a multifactorial disease, but the proliferation of Candida albicans (C. albicans) is the main causative factor. Different modalities have been suggested for the prevention and treatment of DS. Read More

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http://dx.doi.org/10.17219/dmp/112861DOI Listing

Applying the Host-Microbe Damage Response Framework to Pathogenesis: Current and Prospective Strategies to Reduce Damage.

J Fungi (Basel) 2020 Mar 11;6(1). Epub 2020 Mar 11.

Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Disease is a complex outcome that can occur as a result of pathogen-mediated damage, host-mediated damage or both. This has led to the revolutionary concept of the damage response framework (DRF) that defines microbial virulence as a function of host immunity. The DRF outlines six scenarios (classes) of host damage or beneficial outcomes, depending on the microbe and the strength of the immune response. Read More

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http://dx.doi.org/10.3390/jof6010035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151217PMC

Effect of staining and denture cleaning on color stability of differently polymerized denture base acrylic resins.

Authors:
E A Ayaz S Ustun

Niger J Clin Pract 2020 Mar;23(3):304-309

Department of Prosthodontics, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey.

Background: Denture hygiene is an important factor to remove dental plaque and discoloration, to provide optimal oral health, and to prevent denture stomatitis.

Aim: The purpose of this study was to evaluate the effect of coffee staining and denture cleaner on the color stability of two differently polymerized (heat and microwave) denture acrylic resin in vitro.

Materials And Methods: Two commonly used denture base acrylic resins and effervesecnt tablet form denture cleaner were used in this study. Read More

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http://dx.doi.org/10.4103/njcp.njcp_330_19DOI Listing

Guanidine derivative inhibits C. albicans biofilm growth on denture liner without promote loss of materials' resistance.

Bioact Mater 2020 Jun 21;5(2):228-232. Epub 2020 Feb 21.

Dental Materials Laboratory, Postgraduate Program in Dentistry, School of Dentistry, Federal University of Rio Grande Do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, 90035-003, Porto Alegre, RS, Brazil.

To reduce the burden of denture stomatitis and oral candidiasis, an aqueous solution containing polyhexamethylene guanidine hydrochloride (PHMGH) was investigated as an antifungal disinfectant against the leading cause of these oral conditions, . The solutions formulated with concentrations ranging from 0.125 to 0. Read More

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http://dx.doi.org/10.1016/j.bioactmat.2020.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036732PMC

Oral Candidiasis: A Disease of Opportunity.

J Fungi (Basel) 2020 Jan 16;6(1). Epub 2020 Jan 16.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA.

Oral candidiasis, commonly referred to as "thrush," is an opportunistic fungal infection that commonly affects the oral mucosa. The main causative agent, , is a highly versatile commensal organism that is well adapted to its human host; however, changes in the host microenvironment can promote the transition from one of commensalism to pathogen. This transition is heavily reliant on an impressive repertoire of virulence factors, most notably cell surface adhesins, proteolytic enzymes, morphologic switching, and the development of drug resistance. Read More

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http://dx.doi.org/10.3390/jof6010015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151112PMC
January 2020

The effects of three disinfection protocols on Candida spp., denture stomatitis, and biofilm: A parallel group randomized controlled trial.

J Prosthet Dent 2020 Jan 16. Epub 2020 Jan 16.

Associate Professor, Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirao Preto, University of Sao Paulo (USP), Ribeirao Preto, Brazil. Electronic address:

Statement Of Problem: Antifungals are used to treat Candida infections. However, because of increased antifungal resistance and the length of antifungal therapy, Candida spp. infections can be prevented using the prosthesis hygiene method. Read More

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http://dx.doi.org/10.1016/j.prosdent.2019.09.024DOI Listing
January 2020

Efficacy of a propolis solution for cleaning complete dentures.

Am J Dent 2019 Dec;32(6):306-310

Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: The efficacy of a propolis solution against denture biofilm was evaluated by means of an in vitro assessment and a cross-over randomized clinical trial.

Methods: Acrylic resin specimens were contaminated by Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Candida albicans, Candida glabrata, Candida parapsilosis, immersed in a (A) propolis solution, (B) saline or (C) alkaline peroxide, applied onto Petri plates with culture medium and after incubation the number of colonies was counted. For the clinical trial, 30 complete denture wearers were randomly assigned to groups (A) propolis solution, and (B) saline, following one of the sequences (I)A/B or (II) B/A. Read More

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December 2019

Self-perceived oral health among institutionalized older adults in Taubate, Brazil.

Spec Care Dentist 2020 Jan 5;40(1):49-54. Epub 2019 Nov 5.

Department of Preventive and Community Dentistry, The University of Iowa College of Dentistry and Dental Clinics, Iowa City, Iowa.

Purpose/aim: To assess self-perception of oral health among institutionalized older adults in Taubate, Brazil.

Method And Materials: Demographics, oral, and systemic health data were collected from a sample of 89 institutionalized older adults. The Geriatric Oral Health Assessment Index (GOHAI) was applied to assess their self-perception of oral health. Read More

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http://dx.doi.org/10.1111/scd.12430DOI Listing
January 2020

Activity of chitosan antifungal denture adhesive against common Candida species and Candida albicans adherence on denture base acrylic resin.

J Prosthet Dent 2020 Jan 6;123(1):181.e1-181.e7. Epub 2019 Dec 6.

Associate Professor, Department of Microbiology and Research Unit on Oral Microbiology and Immunology, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand; Researcher, Laboratory of Biotechnology, Chulabhorn Research Institute, Lak Si, Bangkok, Thailand. Electronic address:

Statement Of Problem: Candida adherence to the denture base is an important cause of denture stomatitis. In addition, infections with drug-resistant Candida have become more prevalent, especially among elderly and immunocompromised patients. Thus, alternative safe antifungal agents for oral applications are needed. Read More

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http://dx.doi.org/10.1016/j.prosdent.2019.09.026DOI Listing
January 2020

The effect of overnight storage conditions on complete denture colonization by Candida albicans and dimensional stability: A systematic review.

J Prosthet Dent 2019 Nov 28. Epub 2019 Nov 28.

Assistant Professor, Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada.

Statement Of Problem: Overnight removal of complete dentures is recommended to reduce the incidence of denture stomatitis. The effect of overnight storage conditions is unclear.

Purpose: The purpose of this systematic review was to assess the effect of overnight storage conditions on complete denture colonization by Candida albicans and to explore the effect of overnight storage conditions on the dimensional stability of complete dentures. Read More

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http://dx.doi.org/10.1016/j.prosdent.2019.07.014DOI Listing
November 2019

Hygiene protocols for the treatment of denture-related stomatitis: local and systemic parameters analysis - a randomized, double-blind trial protocol.

Trials 2019 Nov 29;20(1):661. Epub 2019 Nov 29.

Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, Brazil.

Background: Denture-related stomatitis (DS) is chronic multifactorial inflammation, strongly related to the presence of the biofilm that is the complex structure formed by microorganisms held together by a mucus-like matrix of carbohydrate that adheres to different surfaces, including the denture surface. DS has recently been correlated with deleterious cardiovascular alterations. The potential effect of hygiene protocols in the control of DS and randomized clinical trials that address this oral condition with cardiovascular complications are important in clinical decision-making. Read More

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http://dx.doi.org/10.1186/s13063-019-3854-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884795PMC
November 2019

Candida-Bacterial Biofilms and Host-Microbe Interactions in Oral Diseases.

Adv Exp Med Biol 2019 ;1197:119-141

Biofilm Research Laboratory, Department of Orthodontics and Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Oral cavity harbors a complex and highly diverse microbial community. Cross-kingdom interactions between Candida and oral bacteria are critical for their co-existence, which may also affect the course and the severity of biofilm-mediated bacterial-mediated diseases. C. Read More

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http://dx.doi.org/10.1007/978-3-030-28524-1_10DOI Listing
November 2019

Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts.

Materials (Basel) 2019 Oct 26;12(21). Epub 2019 Oct 26.

Department of Prosthetic Dentistry, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

Chitosan (CS) and its derivatives show antibacterial and antifungal properties and could help treat and prevent denture stomatitis (DS). Mechanical and surface properties of resilient denture liners were evaluated when modified with CS salts. CS-hydrochloride (CS-HCl) and CS-glutamate (CS-G) were added to resilient denture liners Ufi Gel P and Coe-Soft at four different concentrations (0. Read More

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http://dx.doi.org/10.3390/ma12213518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862088PMC
October 2019

Impact of caffeine on metabolic activity and biofilm formation of Candida albicans on acrylic denture resin in the presence of nicotine.

J Prosthet Dent 2020 Jun 6;123(6):875-879. Epub 2019 Nov 6.

Professor, Biomedical and Applied Sciences and Pathology and Laboratory Medicine, Department of Biomedical and Applied Sciences, Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, Ind.

Statement Of Problem: Candida albicans has been implicated in denture stomatitis, and this effect is exacerbated by nicotine exposure. However, studies have also suggested that caffeine exposure inhibits the growth of C. albicans. Read More

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http://dx.doi.org/10.1016/j.prosdent.2019.09.007DOI Listing

Determination of the effects of cinnamon bark fractions on Candida albicans and oral epithelial cells.

BMC Complement Altern Med 2019 Nov 8;19(1):303. Epub 2019 Nov 8.

Oral Ecology Research Group, Faculty of Dentistry, Université Laval, 2420 Rue de la Terrasse, Quebec City, QC, G1V 0A6, Canada.

Background: Candida albicans is an opportunistic pathogen that causes oral candidiasis and denture stomatitis. It has also been reported to infect oral mucositis lesions in patients who suffer from cancer affecting the head and neck and who receive chemotherapy and radiotherapy treatments. This study aimed to investigate the effects of two cinnamon bark fractions, i. Read More

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http://dx.doi.org/10.1186/s12906-019-2730-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839166PMC
November 2019

The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study.

J Appl Oral Sci 2019 4;27:e20180779. Epub 2019 Nov 4.

Research Unit of Oral Health Sciences, Prosthetic Dentistry and Stomatognathic Physiology, Faculty of Medicine, University of Oulu, Oulu, Finland.

Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients.

Objective: To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle.

Methodology: Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0. Read More

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http://dx.doi.org/10.1590/1678-7757-2018-0779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831028PMC
April 2020
0.803 Impact Factor

Denture stomatitis associated with small-colony variants of Staphylococcus aureus: a case report.

BMC Oral Health 2019 10 11;19(1):219. Epub 2019 Oct 11.

Department of Oral Microbiology, Faculty of Medicine, Medical University of Gdansk, 25 Dębowa St, 80-204, Gdansk, Poland.

Background: The small-colony variants (SCVs) of Staphylococcus aureus were isolated from persistent and recurrent infections, especially after placement of medical devices having direct contact with human tissues. The emergence of SCVs is a survival strategy of S. aureus which enables them to hide inside host's cells and induces a less severe immune response than to wild-type S. Read More

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http://dx.doi.org/10.1186/s12903-019-0910-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788114PMC
October 2019
2 Reads

The Effectiveness of Nigella Sativa Alcoholic Extract on the Inhibition of Candida Albicans Colonization and Formation of Plaque on Acrylic Denture Plates: an In Vitro Study.

J Dent (Shiraz) 2019 Sep;20(3):171-177

Dept. of Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Statement Of The Problem: Due to growing concerns on complications of chemical drugs, the use of herbal extracts has been considered as denture cleaning solutions.

Purpose: The aim of this study was to evaluate the effects of on the cleansing of the formation of plaque on the acrylic resin pieces.

Materials And Method: In this experimental study, 30 pieces of acrylic resin were contaminated by suspension. Read More

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http://dx.doi.org/10.30476/DENTJODS.2019.44911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732174PMC
September 2019

Association between denture stomatitis, candida species and diabetic status.

J Biol Regul Homeost Agents 2019 May-Jun;33(3 Suppl. 1):35-41

Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy.

Candida species are commensal yeasts of the oral cavity, which, under predisposing systemic and/or local circumstances, are responsible for a wide variety of clinical manifestations, globally known as oral candidiasis. Candida-associated denture stomatitis is an oral candidiasis particularly affecting the oral mucosa covered by a dental prosthesis, with several degree of severity. Diabetics suffer oral candidiasis more frequently than healthy individuals do and if they are denture wearers, the risk increases. Read More

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October 2019
4 Reads

Digital Design of a Universal Rat Intraoral Device for Therapeutic Evaluation of a Topical Formulation against -Associated Denture Stomatitis.

Infect Immun 2019 12 18;87(12). Epub 2019 Nov 18.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, Maryland, USA

-associated denture stomatitis (DS) is a persistent and chronic oral infection of the denture-bearing palatal mucosa. DS stems from the ability of the fungal opportunistic pathogen to adhere to denture material and invade palatal tissue. Although DS is the most prevalent form of oral candidiasis, there are currently no feasible therapeutic strategies for the prevention of this recurrent condition. Read More

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http://dx.doi.org/10.1128/IAI.00617-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867832PMC
December 2019
2 Reads

Anti-biofilm Action of Extract, Cytotoxic Potential and Effects on Acrylic Denture Surface.

Front Microbiol 2019 13;10:1724. Epub 2019 Aug 13.

Department of Dentistry, Post-Graduate Program in Dentistry, CEUMA University, São Luís, Brazil.

Considering the challenge to control -associated denture stomatitis, the search for antifungal substances derived from natural sources has become a trend in the literature. In this study the following effects of extract (CAE) were investigated: action against biofilms of , its cytotoxic potential, and changes caused in acrylic resin. The CAE was characterized by High Performance Liquid Chromatography (HPLC). Read More

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http://dx.doi.org/10.3389/fmicb.2019.01724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701195PMC
August 2019
3 Reads
3.941 Impact Factor

Efficacy of photodynamic therapy versus local nystatin in the treatment of denture stomatitis: A randomized clinical study.

Photodiagnosis Photodyn Ther 2019 Dec 24;28:98-101. Epub 2019 Aug 24.

Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Research Chair for Biological Research in Dental Health, College of Dentistry, Riyadh 11545, Saudi Arabia. Electronic address:

Aim: The aim of the present randomized clinical study was to compare the efficacies of photodynamic inactivation (PDI) to nystatin (NST) in terms of prevalence of Candida species in cases with denture stomatitis (DS).

Methods: Thirty-six patients were randomly divided into two groups; 18 in PDI and 18 in NST. Irradiation was carried out by using the GaA1As diode laser with wavelength, mode of transmission, laser output and energy density were standardized at 660 nm, continuous mode, 100 mW power and 28 J/cm2 respectively. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2019.08.028DOI Listing
December 2019
1 Read

Relationship between oral hygiene and fungal growth in patients: users of an acrylic denture without signs of inflammatory process.

Clin Interv Aging 2019 17;14:1297-1302. Epub 2019 Jul 17.

Department of Dental Prosthetics, Institute of Dentistry at Jagiellonian University, Kraków, Poland.

Objectives: To answer to the following questions: is there any relationship between oral hygiene and the growth of yeast in patients without mucosal inflammation; and is there a need for mycological examination patients without mucosal inflammation?

Background: Patients with candidiasis may report varied symptoms, but such infections are most often asymptomatic. In addition to its high incidence in denture users (60%-100%), there is a concern that species from the oral cavity may colonize the upper gastrointestinal tract and lead to septicemia, which has a 40%-79% mortality rate and can require a prolonged hospital stay. It is thus important for all physicians to be aware of the risk factors, diagnosis, and treatment of oral candidiasis in older patients. Read More

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http://dx.doi.org/10.2147/CIA.S193685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643491PMC
December 2019
1 Read

Decreasing Cell Population of Individual Species Does Not Impair the Virulence of and Mixed Biofilms.

Front Microbiol 2019 11;10:1600. Epub 2019 Jul 11.

Laboratory of Pathogenic Biology and Immunology, College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, China.

and are two commonly seen opportunistic fungi in clinical settings and usually co-isolated from the population inflicted with denture stomatitis and oropharyngeal candidiasis. Although and mixed biofilm is deemed to possess enhanced virulence compared with their individual counterparts (especially single biofilm), the relevant descriptions and experimental evidence on the relationship of virulence with their individual cell number in mixed biofilms are contradictory and insufficient. In this study, two standard isolate and eight ones were used to test the cell quantities in their 24- and 48-h single and mixed biofilms. Read More

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http://dx.doi.org/10.3389/fmicb.2019.01600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637850PMC
July 2019
2 Reads

-Cell Interactions Activate Innate Immune Defense in Human Palate Epithelial Primary Cells via Nitric Oxide (NO) and β-Defensin 2 (hBD-2).

Cells 2019 07 12;8(7). Epub 2019 Jul 12.

Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, 17012-901 Bauru, SP, Brazil.

The presence of in the biofilm underlying the dental prosthesis is related to denture stomatitis (DS), an inflammatory reaction of the oral mucosa. The oral epithelium, a component of the innate immune response, has the ability to react to fungal invasion. In this study, we evaluated the in vitro effect of viable on the apoptosis, nitric oxide (NO) production, and β-defensin 2 () expression and production of human palate epithelial cells (HPECs). Read More

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http://dx.doi.org/10.3390/cells8070707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678605PMC
July 2019
2 Reads

Molecular community profiling of the bacterial microbiota associated with denture-related stomatitis.

Sci Rep 2019 07 15;9(1):10228. Epub 2019 Jul 15.

Oral and Biomedical Sciences, School of Dentistry, Cardiff University, Cardiff, UK.

Denture-associated stomatitis (DS) affects over two-thirds of denture-wearers. DS presents as erythema of the palatal mucosa in areas where denture-surface associated polymicrobial biofilms containing the fungus Candida albicans exist. The contribution of the oral bacterial microbiota toward the infection is unknown. Read More

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http://dx.doi.org/10.1038/s41598-019-46494-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629705PMC
July 2019
4 Reads

Contact allergies to dental materials

Swiss Dent J 2019 Jul;129(7-8):571-579

Section of Oral Medicine, Department of Head Medicine and Oral Health, University of Leipzig, Germany

There is a lack of epidemiological data on allergies to dental materials. For example, in the recently published fifth German Oral Health Study (DMS V), no information was given on any common allergies or allergies to dental materials. The aim of the present observational study was therefore to determine the frequencies and symptoms of allergies to dental materials. Read More

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July 2019
4 Reads

Sensitivity to antifungals by Candida spp samples isolated from cases of chronic atrophic candidiasis (CAC).

Braz J Biol 2020 Apr-Jun;80(2):266-272

Programa de Pós-graduação em Odontologia - PPGO, Laboratório de Microbiologia Oral, Faculdade de Odontologia, Universidade Federal de Pelotas - UFPel, Rua Gonçalves Chaves, 457, Sala 702/3, CEP , Pelotas, RS, Brasil.

The treatment of choice for chronic atrophic candidiasis (CAC), also known as denture stomatitis, is topical antifungal therapy. This study aimed to isolate, identify, and assess the antifungal susceptibility of Candida species from mucosal sites in denture wearers with a diagnosis of CAC and determine the prevalence of associated variables. The sample consisted of 44 patients wearing complete or partial dentures who had a clinical diagnosis of CAC. Read More

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http://dx.doi.org/10.1590/1519-6984.190454DOI Listing
June 2020
3 Reads

Evaluation of antibacterial and antifungal properties of a tissue conditioner used in complete dentures after incorporation of ZnO‒Ag nanoparticles.

J Dent Res Dent Clin Dent Prospects 2019 24;13(1):11-18. Epub 2019 Apr 24.

Department of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

. Incorporation of antifungal and antimicrobial agents into tissue conditioners might inhibit the formation of microbial plaque and prevent complications such as denture stomatitis. The present study was carried out to evaluate the antibacterial and antifungal properties of a tissue conditioner after incorporation of ZnO‒Ag nanoparticles into their structure. Read More

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https://joddd.tbzmed.ac.ir/Abstract/joddd-19984
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http://dx.doi.org/10.15171/joddd.2019.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571514PMC
April 2019
8 Reads

Comparison of the efficacy of indocyanine green-mediated photodynamic therapy and nystatin therapy in treatment of denture stomatitis.

Photodiagnosis Photodyn Ther 2019 Sep 8;27:193-197. Epub 2019 Jun 8.

Oral and Dental Disease Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Background: Candida species have an influence in the pathogenesis of denture stomatitis. The current study aimed to investigate the efficacy of indocyanine green (ICG)-mediated photodynamic therapy (PDT) in combination with nystatin mouthwash (PDT + nystatin) for the treatment of denture stomatitis in comparison with routine antifungal therapy with nystatin alone.

Methods: In this double-blind randomized clinical trial, 66 patients were randomly assigned into PDT + nystatin (n = 33) and nystatin (n = 33) groups, both groups were treated 3-times a day (15 days) with nystatin mouthwash, and PDT was performed twice once a week for the PDT + nystatin group. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2019.06.005DOI Listing
September 2019
15 Reads

Antifungal activity and Shore A hardness of a tissue conditioner incorporated with terpinen-4-ol and cinnamaldehyde.

Clin Oral Investig 2019 Jul 20;23(7):2837-2848. Epub 2019 May 20.

School of Dentistry, Federal University of Paraiba, Castelo Branco, Joao Pessoa, Paraiba, Brazil.

Purpose: This study investigated the anti-Candida activity and the Shore A hardness of a tissue conditioner (Softone™) modified by incorporation of terpinen-4-ol and cinnamaldehyde.

Material And Methods: Agar diffusion, microdilution, and mechanism of action methods were performed to determine to evaluate the antifungal activity of phytoconstituents. Then, phytoconstituents in varying concentrations were incorporated into the tissue conditioner. Read More

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http://dx.doi.org/10.1007/s00784-019-02925-wDOI Listing
July 2019
8 Reads

Antimicrobial effect and cytotoxic activity of vinegar-hydrogen peroxide mixture: A possible alternative for denture disinfection.

J Prosthet Dent 2019 Jun 8;121(6):966.e1-966.e6. Epub 2019 May 8.

Professor, Division of Prosthodontics, Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. Electronic address:

Statement Of Problem: Soaking dentures in vinegar or hydrogen peroxide does not seem to remove the microorganisms involved with prosthetic stomatitis efficiently. A mixture of these 2 substances may be effective, but studies are lacking.

Purpose: The purpose of this in vitro study was to evaluate the antimicrobial effect and cytotoxic activity of vinegar-hydrogen peroxide mixtures against Candida albicans and Staphylococcus aureus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223913193021
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http://dx.doi.org/10.1016/j.prosdent.2019.02.019DOI Listing
June 2019
24 Reads

Analysis of risk factors for maxillary denture-related oral mucosal lesions: A cross-sectional study.

Med Oral Patol Oral Cir Bucal 2019 May 1;24(3):e305-e313. Epub 2019 May 1.

Departmento de Medicina Oral e Odontologia Infantil, Universidade Estadual de Londrina (UEL), Rua Pernambuco 540, Londrina, Paraná, Brazil, CEP: 86020-120,

Background: To evaluate the frequency of maxillary dentures-related lesions and the possible associated risk factors.

Material And Methods: Ninety-seven participants were selected, and a complete anamnesis, physical examination and tests of occlusion vertical dimension (OVD), retention and stability of the denture, biofilm quantification, cytopathology, sialometry, pH analysis and buffer capacity of the saliva were performed. Statistical analyses were performed with the Pearson's chi-square, Mann-Whitney tests, and Pearson's coefficient (p<0. Read More

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http://dx.doi.org/10.4317/medoral.22826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530958PMC
May 2019
14 Reads

Effect of Chemical Disinfection on Chitosan Coated PMMA and PETG Surfaces-An In Vitro Study.

Polymers (Basel) 2018 May 16;10(5). Epub 2018 May 16.

Department of Experimental Dentistry, Faculty of Dentistry, Wroclaw Medical University, 26 Krakowska st., 50-425 Wroclaw, Poland.

In oral sciences, chitosan application is of interest due to its antimicrobial and hemostatic activity. Chitosan coating of dentures and other intraoral devices could be beneficial for treatment of denture stomatitis or in the management of postoperative bleeding. Disinfection of dentures and prosthodontic materials is crucial before their use in patients. Read More

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http://dx.doi.org/10.3390/polym10050536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415410PMC
May 2018
4 Reads

Severity of Candida-associated denture stomatitis is improved in institutionalized elders who consume Lactobacillus rhamnosus SP1.

Aust Dent J 2019 09 14;64(3):229-236. Epub 2019 May 14.

Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago, Chile.

Background: This study aimed to determine the effect of the consumption of a probiotic on the clinical characteristics of Candida-associated denture stomatitis (DS) and to determine the impact of a protocol of self-care measures in oral/prosthetic hygiene in institutionalized elders that wear removable prostheses (RP). The current treatment for DS is the systemic use of antifungals, as well as the replacement of these devices together with oral/prosthetic hygiene instructions.

Methods: This study was a randomized, controlled and triple-blind trial. Read More

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http://dx.doi.org/10.1111/adj.12692DOI Listing
September 2019
6 Reads

Retrospective cohort analysis of maxillary overdentures retained by unsplinted implants.

J Prosthet Dent 2019 Sep 1;122(3):301-308.e1. Epub 2019 Apr 1.

Associate Dean for Research; Head, Department of Oral Biology, University of Illinois at Chicago, College of Dentistry, Chicago, Ill.

Statement Of Problem: Implant therapy involving an unsplinted 2-implant-retained overdenture is well defined as a successful treatment for a patient with an edentulous mandible. However, a similar unsplinted implant therapy supporting a maxillary overdenture is not well characterized.

Purpose: The purpose of this retrospective study was to evaluate maxillary overdentures retained by 4 unsplinted implants measuring implant survival, overdenture survival, and patient-reported outcomes. Read More

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http://dx.doi.org/10.1016/j.prosdent.2018.10.014DOI Listing
September 2019
6 Reads

Candida glabrata Has No Enhancing Role in the Pathogenesis of -Associated Denture Stomatitis in a Rat Model.

mSphere 2019 04 3;4(2). Epub 2019 Apr 3.

Department of Prosthodontics, Louisiana State University Health Sciences Center School of Dentistry, New Orleans, Louisiana, USA

Denture stomatitis (DS) is a condition characterized by inflammation of the oral mucosa in direct contact with dentures and affects a significant number of otherwise healthy denture wearers. associated DS is predominantly caused by , a dimorphic fungus that readily colonizes and forms biofilms on denture materials. Previous studies showed a requirement for biofilm formation on both palate and dentures in infection and identified fungal morphogenic transcription factors, Efg1 and Bcr1, as key players in DS pathogenesis. Read More

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http://dx.doi.org/10.1128/mSphere.00191-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449607PMC
April 2019
10 Reads

Salivary Biomarkers in Denture Stomatitis: A Systematic Review.

JDR Clin Trans Res 2019 10 7;4(4):312-322. Epub 2019 Mar 7.

Faculty of Dental Medicine, Université de Montréal, Montreal, QC, Canada.

Objective: Denture stomatitis (DS) is an oral biofilm-associated inflammation of the denture-bearing mucosa. The objective of this review was to identify and evaluate the quality of evidence on the association between the levels of salivary biomarkers and DS among adults with and without palatal DS.

Materials And Methods: Following the PRISMA guidelines, Medline, PubMed, EMBASE, and the Cochrane Central Register for Controlled Trials were searched for eligible studies from the beginning of the archives until December 2018. Read More

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http://dx.doi.org/10.1177/2380084419830941DOI Listing
October 2019
17 Reads

Antifungal effect of tissue conditioners containing poly(acryloyloxyethyltrimethyl ammonium chloride)-grafted chitosan on growth .

J Dent Sci 2018 Jun 9;13(2):160-166. Epub 2018 Feb 9.

Department of Dentistry, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.

Background/purpose: Denture stomatitis is a pathological condition affecting the mucosa underneath ill-fitting dentures, and is considered its main etiologic factor. Tissue conditioners are temporary lining materials often applied to dentures to treat inflamed tissues. However, tissue conditioners do not exert antifungal activity, and the soft surface texture harbors easily. Read More

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http://dx.doi.org/10.1016/j.jds.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388835PMC
June 2018
6 Reads