1,498 results match your criteria Denture Stomatitis


Modulation of Candida albicans virulence in in vitro biofilms by oral bacteria.

Lett Appl Microbiol 2019 Mar 2. Epub 2019 Mar 2.

School of Dentistry, Cardiff University, Cardiff, UK.

Candida-associated denture stomatitis presents as erythema of the palatal mucosa and is caused by biofilms containing the fungus Candida albicans that co-reside with oral bacteria on the denture-fitting surface. This study aimed to assess the effect of several frequently encountered oral bacteria on the expression of Candida albicans virulence factors in in vitro polymicrobial biofilms. Biofilms containing C. Read More

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http://dx.doi.org/10.1111/lam.13145DOI Listing

In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material.

J Clin Exp Dent 2019 Feb 1;11(2):e170-e178. Epub 2019 Feb 1.

BDS, MSc, Lecturer, Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31411, Saudi Arabia.

Background: Denture with antimicrobial activities is desirable to prevent adhesion subsequently decreasing the susceptibility of denture stomatitis incidence. , commonly known as Neem powder has antimicrobial effect but the effect of its addition to acrylic denture base on adhesion has not been investigated. The aim of this study was determine whether adding neem powder to acrylic denture base materials could reduce adhesion. Read More

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http://dx.doi.org/10.4317/jced.55458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383901PMC
February 2019
1 Read

Effectiveness of 405-nm blue LED light for degradation of Candida biofilms formed on PMMA denture base resin.

Lasers Med Sci 2019 Feb 23. Epub 2019 Feb 23.

Department of Oral Medicine and Stomatology, Tsurumi University School of Dental Medicine, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama, Kanagawa, 230-8501, Japan.

This study investigated (i) the degradation effect of 405-nm blue light-emitting diode (LED) light irradiation on Candida albicans and C. glabrata biofilms formed on denture base resin and (ii) the effects of 405-nm blue LED light irradiation on the mechanical and surface characteristics of the resin. Polymethyl methacrylate denture base resin discs were prepared, and C. Read More

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http://dx.doi.org/10.1007/s10103-019-02751-2DOI Listing
February 2019
1 Read

Effectiveness of an Alcohol-Free Chitosan-Curcuminoid Mouthwash Compared with Chlorhexidine Mouthwash in Denture Stomatitis Treatment: A Randomized Trial.

J Altern Complement Med 2019 Feb 13. Epub 2019 Feb 13.

1 Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Thailand.

Objective: An alcohol-free mouthwash of curcuminoids purified from the turmeric (Curcuma longa Linn.) rhizome was formulated using a cosolvent system, comprising chitosan and polyethylene glycol (PEG) 400, and determined for its efficacy and safety in management of denture stomatitis (DS) in comparison with a chlorhexidine (CHX) mouthwash.

Design: A single-center, randomized, controlled parallel-arm trial was conducted. Read More

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http://dx.doi.org/10.1089/acm.2018.0459DOI Listing
February 2019
2 Reads

Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities.

Head Neck Pathol 2019 Mar 29;13(1):4-15. Epub 2019 Jan 29.

The Ohio State University, 305 W. 12 Ave, Columbus, OH, 43210, USA.

Erythematous lesions of the oral mucosa are common and can reflect a variety of conditions, ranging from benign reactive or immunologically-mediated disorders to malignant disease. Together with vascular abnormalities, which can vary from reddish to bluish-purple in color, the differential diagnosis for erythematous oral mucosal change is quite diverse. This review focuses on salient clinical features and histopathologic findings of selected conditions which clinically present as red or vascular-like oral mucosal alterations, including oral vascular malformations and neoplasms, pyogenic granuloma, localized juvenile spongiotic gingival hyperplasia, denture stomatitis, benign migratory glossitis (geographic tongue), orofacial granulomatosis, granulomatosis with polyangiitis (Wegener granulomatosis), megaloblastic anemia, and erythroplakia. Read More

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http://dx.doi.org/10.1007/s12105-019-01002-8DOI Listing
March 2019
2 Reads

Prevalence of oral mucosal lesions in young seniors in the Wrocław region.

Dent Med Probl 2018 Oct-Dec;55(4):405-410

Department of Periodontology, Faculty of Dentistry, Wroclaw Medical University, Poland.

Background: The morbidity of certain oral pathologies, for example denture-related stomatitis, burning mouth syndrome (BMS) and benign neoplasms is higher in the elderly. It is necessary to periodically assess the changes in the profile of the occurrence of these diseases and determine the dominant risk factors associated with their incidence.

Objectives: The aim of the study was to evaluate the prevalence of oral mucosal pathologies (in particular, potentially malignant and cancerous disorders) in a randomly selected population of 65-74-year-old residents of Wrocław and Oława, Poland. Read More

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http://www.dmp.umed.wroc.pl/en/article/2018/55/4/405/
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http://dx.doi.org/10.17219/dmp/97310DOI Listing
January 2019
18 Reads

In vivo biocompatibility of an interim denture resilient liner containing antifungal drugs.

J Prosthet Dent 2019 Jan 29;121(1):135-142. Epub 2018 Jun 29.

Associate Professor, Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil. Electronic address:

Statement Of Problem: Antifungal agents incorporated into interim denture resilient liners have been suggested as an adjunct treatment for denture stomatitis (DS). However, before applying this protocol to humans, biocompatibility analysis of such drugs in animal models is required.

Purpose: The purpose of this animal study was to evaluate the in vivo biocompatibility of an interim resilient liner modified with minimum inhibitory concentrations (MICs) of antifungal drugs for Candida albicans biofilm. Read More

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http://dx.doi.org/10.1016/j.prosdent.2018.02.005DOI Listing
January 2019
1 Read

Efficacy of extract against species in patients with denture stomatitis.

Curr Med Mycol 2018 Sep;4(3):15-18

Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.

Background And Purpose: Denture stomatitis is a chronic inflammation disease of the oral mucosa, which is specified by erythematous lesions mainly in the upper palate. Nystatin as a polyene, a class of antifungal agents, is one of the effective drugs to treat denture stomatitis. Considering the expansion of utilizing herbal drugs to cure many kinds of diseases, the present study was conducted to investigate the effects of (green tea), which has the most chemical and influence similarity with nystatin, against denture stomatitis. Read More

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http://publish.kne-publishing.com/index.php/CMM/article/view
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http://dx.doi.org/10.18502/cmm.4.3.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315200PMC
September 2018
9 Reads

Do the oral strains from denture wearers have a greater pathogenicity potential?

J Oral Microbiol 2019 23;11(1):1536193. Epub 2018 Oct 23.

Department of Pathophysiology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.

We used flow cytometry to compare the phagocytic activity of monocytes against strains (both biofilm and planktonic cells) isolated from denture wearers and non-wearers. Staphylococcal strains were cultured in Brain Heart Infusion broth in both planktonic and biofilm form and were stained with a fluorescent reporter (propidium iodide) and incubated with monocytes. The fluorescence of the monocytes containing phagocytized bacteria was determined by flow cytometry and normalized to that of the bacterial strains used in the experiment. Read More

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http://dx.doi.org/10.1080/20002297.2018.1536193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225501PMC
October 2018

In-vitro antifungal efficacy of tissue conditioner-chitosan composites as potential treatment therapy for denture stomatitis.

Int J Biol Macromol 2019 Mar 10;125:761-766. Epub 2018 Dec 10.

Department of Dental Materials, Army Medical College, NUMS, Pakistan. Electronic address:

Tissue conditioners are commonly used to improve the adaptation of ill-fitting dentures. These materials are easily colonized by Candida albicans (C. albicans), resulting in "denture stomatitis". Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2018.12.091DOI Listing

Differential Mucosal Gene Expression Patterns in Candida-Associated, Chronic Oral Denture Stomatitis.

J Prosthodont 2019 Feb 6;28(2):202-208. Epub 2019 Jan 6.

Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy, New York, NY.

Purpose: Denture stomatitis is a common condition manifested by inflammation of the oral mucous membrane beneath a denture. The objective of this study was to compare the transcriptome of human palatal mucosa with chronic oral stomatitis-associated Candida albicans infection to that of healthy oral mucosa.

Materials And Methods: Oral palatal biopsies were obtained from 17 healthy and 15 C. Read More

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http://dx.doi.org/10.1111/jopr.13007DOI Listing
February 2019
2 Reads
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Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species.

Arch Oral Biol 2019 Feb 1;98:258-264. Epub 2018 Dec 1.

National Reference Medical Mycology Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, dr Subotića 1, 11000, Belgrade, Serbia.

Objective: The upward trend in using plant materials introduced essential oils (EOs) as a valuable, novel, bioactive antifungal agent and as an alternative to standard treatment protocol of denture stomatitis caused by Candida species. Therefore, the aim was to evaluate the antifungal activity of different EOs and to present the response surface methodology (RSM) and artificial neural network (ANN) as possible tools for optimizing and predicting EOs antifungal activity.

Methods: Minimum inhibitory concentration (MIC) and Minimum fungicidal concentration (MFC) of the EOs against 3 species Candida spp. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2018.11.029DOI Listing
February 2019
1 Read

Sodium bicarbonate: A review and its uses in dentistry.

Indian J Dent Res 2018 Sep-Oct;29(5):672-677

Department of Prosthetic Dentistry, Birmingham Dental Hospital, Birmingham B57EG, UK.

Denture stomatitis, periodontitis, and peri-implantitis are the growing problems in restorative dentistry. Chemicals play an important role as an adjuvant to mechanical cleaning of teeth, implants, surrounding tissues, and prostheses. Current mouth rinses are reported to affect the tissues and prostheses if used on a long-term basis. Read More

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http://www.ijdr.in/text.asp?2018/29/5/672/244935
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http://dx.doi.org/10.4103/ijdr.IJDR_30_17DOI Listing
November 2018
14 Reads

Evaluation of the effect of denture cleansers on the surface roughness of hard denture base material: An study.

Indian J Dent Res 2018 Sep-Oct;29(5):657-662

Department of Prosthodontics, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

Background: Maintaining the oral hygiene of denture wearers is a challenge faced in modern dentistry. Biofilm formed on dentures has been associated with denture stomatitis, malodor, aspiration pneumonia, infectious endocarditis, gastrointestinal infection, and chronic obstructive pulmonary disease.

Objective: The purpose of this study was to evaluate the effect of denture cleansers on the surface roughness of hard denture base material. Read More

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http://www.ijdr.in/text.asp?2018/29/5/657/244954
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http://dx.doi.org/10.4103/ijdr.IJDR_810_16DOI Listing
November 2018
7 Reads

A critical review of protocols for conventional microwave oven use for denture disinfection.

Community Dent Health 2018 Oct 16. Epub 2018 Oct 16.

Private Practice, Cavalhada Avenue, Porto Alegre, Brazil.

Introduction: The lack of proper denture hygiene may cause denture stomatitis and be detrimental to older adults' health. The cleaning of complete dentures should be quick, efficient, and easy to perform, although it might not guarantee disinfection. The use of a microwave oven has been suggested for aiding in the disinfection of complete dentures, but lacks a gold standard protocol. Read More

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http://dx.doi.org/10.1922/CDH_4372Brondani07DOI Listing
October 2018

Kinetics of antifungal activity of home-generated ozonated water on .

Curr Med Mycol 2018 Jun;4(2):27-31

Department of Prosthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Background And Purpose: -associated denture stomatitis is one of the most common forms of oral candidiasis among denture wearers. Regarding this, the aim of the present study was to evaluate the antifungal effects of home-generated ozonated water on the adhesion of the C. attached to the surface of the denture base acrylic resins. Read More

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http://dx.doi.org/10.18502/cmm.4.2.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181063PMC
June 2018
8 Reads

Protein-repellent and antibacterial effects of a novel polymethyl methacrylate resin.

J Dent 2018 Dec 21;79:39-45. Epub 2018 Sep 21.

Department of Orthodontics, School of Stomatology, Capital Medical University, Beijing, 100050, China. Electronic address:

Objectives: Heat-cured resins are commonly used in orthodontics; however, there is a high incidence of caries, periodontal diseases and denture-induced stomatitis. The objectives of this study were to: (1) develop a new bioactive polymethyl methacrylate (PMMA) resin containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and quaternary ammonium dimethylaminohexadecyl methacrylate (DMAHDM), and (2) investigate the effects on mechanical properties, protein-repellency and antibacterial properties.

Methods: MPC and DMAHDM were mixed into a commercial acrylic resin (Nature Cryl™ MC). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03005712183048
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http://dx.doi.org/10.1016/j.jdent.2018.09.007DOI Listing
December 2018
8 Reads

Epidemiology of oral mucosal lesions in Slovenia.

Radiol Oncol 2018 Sep 11;52(3):263-266. Epub 2018 Sep 11.

Private Dental Practice, Ljubljana, Slovenia.

Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not the most common lesions that might appear in the oral cavity. Since most of the studies are focused on the detection of cancer in the oral cavity, we were interested in detecting the frequency of benign changes of the oral mucosa in Slovene population. Oral mucosal lesions are important pointer of oral health and quality of life, especially in elderly. Read More

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http://dx.doi.org/10.2478/raon-2018-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137360PMC
September 2018
1 Read

Viability of Candida albicans in Denture Base Resin After Disinfection: A Preliminary Study.

Int J Prosthodont 2018 Sep/Oct;31(5):436-439

Purpose: To quantify the depth of penetration of Candida albicans (C albicans) into a denture base resin and to investigate its viability after disinfection.

Materials And Methods: Heat-polymerizing polymethyl methacrylate plates were contaminated with C albicans, then washed, dried, and prepared for scanning electron microscopy (SEM). Vertical surfaces were cut, and the depth of any penetration was measured. Read More

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http://dx.doi.org/10.11607/ijp.5653DOI Listing
December 2018

Do raspberry extracts and fractions have antifungal or anti-adherent potential against Candida spp.?

Int J Antimicrob Agents 2018 Dec 1;52(6):947-953. Epub 2018 Sep 1.

Université de Poitiers, UMR CNRS 7267, Laboratoire Ecologie et Biologie des Interactions, Equipe Microbiologie de l'Eau, F-86073 Poitiers, France. Electronic address:

Candida spp., especially Candida albicans, is one of the main colonisers of the oral cavity. Due to its ability to form biofilms, it can be implicated in dental caries, periodontal disease and denture stomatitis. Read More

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http://dx.doi.org/10.1016/j.ijantimicag.2018.08.020DOI Listing
December 2018
4 Reads

Properties of an acrylic resin after immersion in antiseptic soaps: Low-cost, easy-access procedure for the prevention of denture stomatitis.

PLoS One 2018 30;13(8):e0203187. Epub 2018 Aug 30.

Department of Dental Materials and Prosthodontics, São Paulo State University (UNESP), Dental School, Araraquara, São Paulo, Brazil.

Denture stomatitis triggered by Candida species requires better preventive measures. This study evaluated the physical and biological properties of a denture base acrylic resin after immersion in antiseptic soaps. Acrylic resin specimens were prepared and stored in distinct solutions for 0, 7, 14, 21, and 28 days. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203187PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117035PMC
February 2019
2 Reads

Effects of Linn. Extract on biofilms developed on denture acrylic resin discs.

J Clin Exp Dent 2018 Jul 1;10(7):e642-e647. Epub 2018 Jul 1.

Post-Graduate Program in Dentistry, CEUMA University, São Luis, Maranhao, Brazil.

Background: Considering the prevalence of denture stomatitis and the challenge of controlling this pathology using conventional therapies, natural products have been suggested as important therapeutic alternatives due to their antifungal and anti-biofilm properties. Thus, this study investigated if immersion in Linn. extract (TCE) affects biofilms developed on denture acrylic resin discs. Read More

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http://dx.doi.org/10.4317/jced.54776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057082PMC

A Proposal of Remedies for Oral Diseases Caused by Candida: A Mini Review.

Front Microbiol 2018 9;9:1522. Epub 2018 Jul 9.

School of Dental Medicine, Tsurumi University, Yokohama, Japan.

An opportunistic pathogen, Candida is not only related to oral problems such as oral candidiasis and denture stomatitis, but also to systemic diseases such as aspiration pneumonia and fungemia. The carriage rate of Candida species in the oral cavity of individuals wearing dentures and with removable orthodontic appliances, has increased. Moreover, it is one of the causal pathogens in refractory infected root canals because of its resistance to antifungal drugs in root canal therapy and poses a great challenge during the treatment of patients. Read More

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http://dx.doi.org/10.3389/fmicb.2018.01522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046406PMC

The Impact of Nicotine and Cigarette Smoke Condensate on Metabolic Activity and Biofilm Formation of Candida albicans on Acrylic Denture Material.

J Prosthodont 2018 Jul 20. Epub 2018 Jul 20.

Department of Biomedical and Applied Sciences, Indiana University School of Dentistry, Indianapolis, IN.

Purpose: Smokers have increased denture stomatitis caused primarily by Candida albicans. The primary aim of this study was to demonstrate the impact of a wide range of nicotine and cigarette smoke condensate (CSC) concentrations on biofilm formation and metabolic activity of C. albicans on acrylic denture material. Read More

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http://dx.doi.org/10.1111/jopr.12945DOI Listing
July 2018
4 Reads

Examination of 2-methacryloyloxyethyl phosphorylcholine polymer coated acrylic resin denture base material: surface characteristics and Candida albicans adhesion.

J Mater Sci Mater Med 2018 Jul 3;29(7):107. Epub 2018 Jul 3.

Faculty of Dentistry, Department of Microbiology, Gazi University, Ankara, Turkey.

The aim of this study is to evaluate the effects of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coating with various concentrations onto acrylic resin denture base material on surface characteristics such as contact angle and surface roughness and on Candida albicans adhesion which is the major factor of denture stomatitis. Specimens, prepared from heat-polymerized acrylic denture base material, were divided into control and three test groups, randomly. Surfaces of the specimens in test groups were coated with poly(MPC) (PMPC) by graft polymerization of MPC in different concentrations (0. Read More

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http://link.springer.com/10.1007/s10856-018-6116-7
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http://dx.doi.org/10.1007/s10856-018-6116-7DOI Listing
July 2018
5 Reads

Characterization of Herbal Antifungal Agent, against Oral spp. Isolated from Patients with -Associated Denture Stomatitis: An Study.

Contemp Clin Dent 2018 Jun;9(Suppl 1):S3-S10

Department of Prosthodontics, Sri Ramakrishna Dental College and Hospitals, Coimbatore, Tamil Nadu, India.

Background: Candida Associated Denture Stomatitis is the prevalent fungal pathosis in denture wearers, especially in immunocompromized patients. Existing antifungal agents are ineffective since the Candida species become resistant and also, they become toxic. Origanum vulgare is a herbal plant with high anti-fungal activity against Candida of blood and urine origin. Read More

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http://dx.doi.org/10.4103/ccd.ccd_537_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006875PMC
June 2018
5 Reads

In Vitro Evaluation of Adhesion of Candida albicans on CAD/CAM PMMA-Based Polymers.

J Prosthodont 2019 Feb 1;28(2):e873-e879. Epub 2018 Jul 1.

Department of Medical Microbiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To compare the amount of adherent Candida albicans to different CAD/CAM poly(methyl methacrylate) (PMMA)-based polymers and conventional heat-polymerized PMMA after long-term thermal cycling.

Materials And Methods: The specimens were subjected to 10,000 thermal cycles (5-55°C) and divided into two groups, uncoated and pellicle-coated. Surface roughness and contact angles of the specimens were measured. Read More

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http://dx.doi.org/10.1111/jopr.12942DOI Listing
February 2019
17 Reads

Denture-Associated Oral Microbiome and Periodontal Disease Causing an Anaerobic Pyogenic Liver Abscess in an Immunocompetent Patient: A Case report and Review of the Literature.

Gastroenterology Res 2018 Jun 31;11(3):241-246. Epub 2018 May 31.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St Louis, MO, USA.

Pyogenic liver abscesses (PLA) develop from the spread of infection through the portal circulation, biliary infections or arterial hematogenous seeding in the setting of systemic infections. PLA are often poly-microbial and are uncommonly reported to be due to anaerobic species. We report the case of a previously healthy, immunocompetent 63-year-old man with hepatic abscesses as a result of periodontal disease. Read More

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http://dx.doi.org/10.14740/gr1006wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997471PMC
June 2018
21 Reads

In Vitro Antifungal Susceptibility of Species Isolated from Iranian Patients with Denture Stomatitis.

Biomed Res Int 2018 16;2018:3086586. Epub 2018 May 16.

Department of Medical Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Background: -associated denture stomatitis (CADS) is a common fungal infection in people who wear dentures. The main objective of this study was to make molecular identification of causative agents of CADS and in vitro antifungal susceptibility testing (AFST) in the Iranian patients with denture stomatitis.

Methods: A total of 134 spp. Read More

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https://www.hindawi.com/journals/bmri/2018/3086586/
Publisher Site
http://dx.doi.org/10.1155/2018/3086586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977002PMC
October 2018
2 Reads

Chair-Side Direct Microscopy Procedure for Diagnosis of Oral Candidiasis in an Adolescent.

Case Rep Dent 2018 29;2018:6561735. Epub 2018 Apr 29.

Department of Pediatric Dentistry, Toulouse Dental School, University of Toulouse III, Toulouse University Hospital, Toulouse, France.

Oral candidiasis is caused by fungi of the genus and one of the most common opportunistic fungal infections of the human oral cavity. Given the clinical variability of this disease, microbiological techniques are often required for clinical confirmation, as well as establishing a differential diagnosis with other diseases. The aim of this brief technical report is to illustrate a simple chair-side method, which can provide immediate microscopic diagnosis of this disease. Read More

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http://dx.doi.org/10.1155/2018/6561735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949180PMC

Role of laser or photodynamic therapy in treatment of denture stomatitis: A systematic review.

J Prosthet Dent 2018 Oct 25;120(4):498-505. Epub 2018 May 25.

Associate Professor, Dental Implants Research Center and Department of Prosthodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Statement Of Problem: Denture stomatitis (DS) is an inflammatory oral lesion that occurs mostly in elderly denture wearers and that can negatively affect their quality of life. The conventional treatment plan for DS is topical or systemic fungicidal drug therapy, which are not without side effects.

Purpose: The purpose of this systematic review was to evaluate the clinical outcomes of using low-level laser therapy (LLLT) or photodynamic therapy (PDT) in the treatment of DS by reviewing high-quality published articles. Read More

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http://dx.doi.org/10.1016/j.prosdent.2018.01.003DOI Listing
October 2018
3 Reads

The severity of denture stomatitis as related to risk factors and different Candida spp.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Mar 22. Epub 2018 Mar 22.

National Reference Medical Mycology Laboratory, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Serbia. Electronic address:

Objectives: 1) To select patients with Candida-related denture stomatitis (DS) and to study possible risk factors associated with DS, 2) to evaluate the severity of DS according to Newton's classification, and 3) to investigate the association between the presence of non-albicans Candida spp. (NAC) or mixed Candida spp. and the severity of DS. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.03.003DOI Listing
March 2018
2 Reads

Mechanical and Physicochemical Properties of Newly Formed ZnO-PMMA Nanocomposites for Denture Bases.

Nanomaterials (Basel) 2018 May 6;8(5). Epub 2018 May 6.

Department of Prosthodontics, Medical University of Warsaw, 02-006 Warsaw, Poland.

Aim: The aim of this study was to investigate the selected properties of zinc oxide- polymethyl methacrylate (ZnO-PMMA) nanocomposites that can influence the microorganism deposition on their surface.

Materials And Methods: Non-commercial ZnO-NPs were prepared, characterized and used for the preparation of PMMA nanocomposite. Roughness, absorbability, contact angle and hardness of this new nanomaterial were evaluated. Read More

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http://www.mdpi.com/2079-4991/8/5/305
Publisher Site
http://dx.doi.org/10.3390/nano8050305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977319PMC
May 2018
9 Reads

Photodynamic inactivation of Candida ssp. on denture stomatitis. A clinical trial involving palatal mucosa and prosthesis disinfection.

Photodiagnosis Photodyn Ther 2018 Jun 17;22:212-216. Epub 2018 Apr 17.

Centro de Lasers e Aplicações, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, São Paulo, Brazil. Electronic address:

Denture stomatitis (DS) is the most common oral fungal infection in denture wearers. Photodynamic inactivation (PDI) has been showing to be an effective technique in vivo against fungi, including fungal infections in the oral cavity. The disinfection of both oral mucosa and denture may represent a real advantage in terms of fungus control. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2018.04.008DOI Listing
June 2018
4 Reads

Photodynamic inactivation in the expression of the Candida albicans genes ALS3, HWP1, BCR1, TEC1, CPH1, and EFG1 in biofilms.

Lasers Med Sci 2018 Sep 27;33(7):1447-1454. Epub 2018 Mar 27.

Department of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, Campus of São José dos Campos, Engenheiro Francisco José Longo Avenue, 777, Jardim São Dimas, São José dos Campos, São Paulo, CEP 12245-000, Brazil.

The objective of this study was to evaluate the effects of photodynamic inactivation (PDI) on Candida albicans biofilms, evaluating its effects on gene expression of ALS3, HWP1, BCR1, TEC1, CPH1, and EFG1 by yeast. Three samples of C. albicans were used in this study: a clinical sample from a patient with HIV (39S), a clinical sample from a patient with denture stomatitis lesion (Ca30), and a standard strain ATCC 18804. Read More

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http://dx.doi.org/10.1007/s10103-018-2487-8DOI Listing
September 2018
7 Reads

New paste for severe stomatitis in patients undergoing head-and-neck cancer radiotherapy and/or chemotherapy with oral appliance.

BMC Cancer 2018 03 2;18(1):245. Epub 2018 Mar 2.

Department of Dentistry and Oral Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.

Background: The aim of the present study was to evaluate the physical properties of "admixture paste", which is a commercially available gel containing hinokitiol for use against severe stomatitis, and its characteristics as a moisturizing gel and denture adhesive.

Methods: The admixture paste, which contained dexamethasone (Dexaltin®), gel for oral care (Refrecare H®) and petrolatum, and its 3 components, either alone or in different combinations, were subjected to viscosity, adhesiveness and elution testing to compare their physical properties. Viscosity was measured with a stress-controlled rheometer. Read More

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http://dx.doi.org/10.1186/s12885-018-4017-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834906PMC
March 2018
12 Reads

Management of denture stomatitis: a narrative review.

J Biol Regul Homeost Agents 2018 Jan-Feb;32(2 Suppl. 1):113-116

Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.

Candida albicans is a typical commensal microorganism of the oral cavity that can become virulent in certain conditions and cause denture stomatitis (DS). Many conditions can predispose for DS, including local and systemic alterations. The therapeutical approach to DS is various and both topical and systemic alternatives can be considered. Read More

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February 2019
13 Reads

Denture-associated biofilm infection in three-dimensional oral mucosal tissue models.

J Med Microbiol 2018 Mar 11;67(3):364-375. Epub 2018 Jan 11.

1​Oral and Biomedical Sciences, School of Dentistry, Cardiff University, Cardiff, UK.

Purpose: In vitro analyses of virulence, pathogenicity and associated host cell responses are important components in the study of biofilm infections. The Candida-related infection, denture-associated oral candidosis, affects up to 60 % of denture wearers and manifests as inflammation of palatal tissues contacting the denture-fitting surface. Commercially available three-dimensional tissue models can be used to study infection, but their use is limited for many academic research institutions, primarily because of the substantial purchase costs. Read More

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http://dx.doi.org/10.1099/jmm.0.000677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882079PMC
March 2018
3 Reads

Cytokine gene polymorphism in denture stomatitis patients: A clinical study.

Oral Dis 2018 Sep 11;24(6):983-992. Epub 2018 Jun 11.

Department of Prosthodontics, Faculty of Health, School of Dentistry, Witten/Herdecke University, Witten, Germany.

Objective: This clinical study investigated the association between cytokine gene polymorphism and Candida growth in denture stomatitis (DS) patients.

Subjects And Methods: Saliva and blood samples of 160 complete denture wearers (80 healthy controls and 80 with DS) were collected for mycological and gene polymorphism testing, respectively. Salivary Candida growth and TNF-α, TGF-β, IL-6, and IL-10 genotypes were investigated. Read More

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http://doi.wiley.com/10.1111/odi.12844
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http://dx.doi.org/10.1111/odi.12844DOI Listing
September 2018
2 Reads

Effect of incorporation of surface pre-reacted glass ionomer filler in tissue conditioner on the inhibition of Candida albicans adhesion.

Dent Mater J 2018 Jun 8;37(3):453-459. Epub 2018 Feb 8.

Removable Partial Prosthodontics, Tokyo Medical and Dental University (TMDU).

We investigated the effects of incorporation of surface pre-reacted glass ionomer (S-PRG) filler in tissue conditioner (TC) on Candida albicans adhesion. We prepared specimens containing 0, 5, 10, or 20 wt% of S-PRG filler, and measured the amount of C. albicans on the surface using a colony forming unit (CFU) assay and scanning electron microscopic images. Read More

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http://dx.doi.org/10.4012/dmj.2017-171DOI Listing
June 2018
3 Reads

Evaluation of biofilm formation on various parts of implant material surfaces.

Niger J Clin Pract 2018 Jan;21(1):33-37

Department of Periodontology, Faculty of Dentistry, Ordu University, Ordu, Turkey.

Aims: Candida albicans adhesion to any oral substrata is the first and essential stage in forming a pathogenic fungal biofilm. In general, yeast cells have remarkable potential to adhere to host surfaces, such as teeth or mucosa, and to artificial, non-biological surfaces, such as dental materials. C. Read More

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http://dx.doi.org/10.4103/1119-3077.224793DOI Listing
January 2018

Evaluation of anti-enzyme properties of Origanum vulgare essential oil against oral Candida albicans.

J Mycol Med 2018 Mar;28(1):94-100

Department of restorative dentistry, school of dentistry, Federal university of Pelotas, 457, street Gonçalves Chaves, Downtown, 96015-560 Pelotas - RS, Brazil. Electronic address:

This study aimed to evaluate the anti-enzymatic activity of Origanum vulgare (oregano) essential oil against 15 strains of Candida albicans. Candida albicans samples were isolated from the oral mucosa of patients with denture stomatitis treated in a Dentistry school on a public university. Preparation of the inoculum was performed with a suspension of C. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11565233173034
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http://dx.doi.org/10.1016/j.mycmed.2017.12.001DOI Listing
March 2018
15 Reads

Superhydrophilic co-polymer coatings on denture surfaces reduce Candida albicans adhesion-An in vitro study.

Arch Oral Biol 2018 Mar 27;87:143-150. Epub 2017 Dec 27.

Department of Removable Partial Prosthodontics, Graduate School, Tokyo Medical and Dental University (TMDU), 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan. Electronic address:

Objective: In this study, we aimed to investigate denture-base-resin coatings prepared with a crosslinkable co-polymer containing sulfobetaine methacrylamide (SBMAm) and the relationship between their surface characteristics and the initial adhesion of Candida albicans (C. albicans).

Methods: Acrylic resin discs were coated with co-polymers containing various concentrations of SBMAm and N,N'-(4,7,10-trioxa-1,13-tridecadiamine) diacrylamide (JDA) as crosslinking agent. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2017.12.024DOI Listing
March 2018
14 Reads

Denture Stomatitis: Causes, Cures and Prevention.

Prim Dent J 2017 Dec;6(4):46-51

Removable dentures are worn by 20% of the UK population and two thirds of these individuals have denture stomatitis. Poor oral hygiene is commonplace among this group, as is smoking and xerostomia, which also contribute to the development of denture stomatitis. A complex polymicrobial biofilm is able to proliferate on the surface of denture materials and matures to form visible denture plaque. Read More

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http://dx.doi.org/10.1308/205016817822230175DOI Listing
December 2017
5 Reads

Antimicrobial activity of denture adhesive associated with Equisetum giganteum- and Punica granatum-enriched fractions against Candida albicans biofilms on acrylic resin surfaces.

Biofouling 2018 01 18;34(1):62-73. Epub 2017 Dec 18.

a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry , University of São Paulo , Bauru , Brazil.

Candida biofilms adhere to the internal surface of removable dentures, which is an etiological factor in the pathogenesis of denture stomatitis (DS). Adhesive materials are used at the base of maxillary complete dentures to improve their retention and chewing qualities. This article reports the antimicrobial activity of the enriched fractions of Equisetum giganteum and Punica granatum incorporated into a denture adhesive against C. Read More

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http://dx.doi.org/10.1080/08927014.2017.1407408DOI Listing
January 2018
19 Reads

Antimicrobial Photodynamic Therapy mediated by Photodithazine in the treatment of denture stomatitis: A case report.

Photodiagnosis Photodyn Ther 2018 Mar 2;21:168-171. Epub 2017 Dec 2.

Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp), School of Dentistry, Rua Humaitá, 1680, 14801-903, Araraquara, SP, Brazil. Electronic address:

Antimicrobial Photodynamic Therapy (aPDT) mediated by Photodithazine (PDZ) has shown efficacy in the inactivation of Candida spp. in in vitro and in vivo studies. This preliminary study reports five clinical cases of patients with denture stomatitis (DS) treated with PDZ-mediated aPDT. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2017.11.018DOI Listing
March 2018
5 Reads

Adherence of to complete denture surfaces : A comparison of conventional and CAD/CAM complete dentures.

J Adv Prosthodont 2017 Oct 16;9(5):402-408. Epub 2017 Oct 16.

Department of Pathology, School of Medicine, King Saud University, Riyadh, Saudi Arabia.

Purpose: The goal of this study was to compare the adhesion of to the surfaces of CAD/CAM and conventionally fabricated complete denture bases.

Materials And Methods: Twenty discs of acrylic resin poly (methyl methacrylate) were fabricated with CAD/CAM and conventional procedures (heat-polymerized acrylic resin). The specimens were divided into two groups: 10 discs were fabricated using the CAD/CAM procedure (Wieland Digital Denture Ivoclar Vivadent), and 10 discs were fabricated using a conventional flasking and pressure-pack technique. Read More

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http://dx.doi.org/10.4047/jap.2017.9.5.402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673618PMC
October 2017
6 Reads

Effect of Incorporation of Antifungal Agents on the Ultimate Tensile Strength of Temporary Soft Denture Liners.

J Prosthodont 2018 Feb 14;27(2):177-181. Epub 2017 Nov 14.

Department of Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil.

Purpose: To investigate the ultimate tensile strength of temporary soft denture liners modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm (SC5314) determined in previous microbiological research.

Materials And Methods: Dumbbell-shaped specimens (n = 7) with a central cross-sectional area of 6 × 3 × 33 mm were produced by Softone and Trusoft, without (control) or with incorporation of drugs in powder form at MICs for C. albicans biofilm (per g of material powder): nystatin (0. Read More

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http://dx.doi.org/10.1111/jopr.12660DOI Listing
February 2018
8 Reads

Hygiene practices in removable prosthodontics: A systematic review.

Int J Dent Hyg 2018 May 9;16(2):179-201. Epub 2017 Nov 9.

Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.

Objective: To systematically review the recent scientific evidence about the hygiene practices of removable prostheses relative to the effectiveness, colour and dimensional stability. This review aimed also to identify patients' attitudes and habits towards denture hygiene.

Methods: Three electronic databases (MEDLINE/PubMed, Scopus and Cochrane Library) were screened, in English language, between January 1995 and December 2016. Read More

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http://dx.doi.org/10.1111/idh.12323DOI Listing
May 2018
3 Reads

Surface Roughness Changes in Denture Liners in Denture Stomatitis Patients.

Int J Prosthodont 2017 November/December;30(6):561–564. Epub 2017 Oct 30.

Purpose: This randomized clinical trial assessed how surface roughness (Ra) in resilient liners was affected by soft tissue health conditions and time-related aspects in patients with complete dentures.

Methods: Specimens of acrylic resin (control) and denture liners (silicone-based or acrylic resin-based) were inserted into the dentures of patients with and without denture stomatitis (n = 30). Ra was evaluated before denture insertion and after 7, 14, and 21 days of prosthesis wearing. Read More

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http://dx.doi.org/10.11607/ijp.5108DOI Listing
February 2018
2 Reads