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    1425 results match your criteria Denture Stomatitis

    1 OF 29

    Photodvnamic Therapy in Endodontics.
    J Contemp Dent Pract 2017 Jun 1;18(6):534-538. Epub 2017 Jun 1.
    Department of Conservative Dentistry, Showa University Dental Hospital, Tokyo, Japan.
    Commonly used irrigants do not always eradicate the entire microbial flora in infected root canals. Therefore, several other strategies, such as photodynamic therapy (PDT) have been developed. Photoactivated disinfection is based on the interaction of a photosensitive antibacterial agent and a light source. Read More

    Nicotine Upregulates Coaggregation of Candida albicans and Streptococcus mutans.
    J Prosthodont 2017 Jun 9. Epub 2017 Jun 9.
    Department of Biomedical and Applied Sciences, Indiana University School of Dentistry, Indianapolis, IN.
    Purpose: Denture stomatitis is a condition of painless inflammation of denture-bearing mucosa. Reports indicate that nicotine, the major psychoactive ingredient in tobacco, increases growth of Streptococcus mutans and Candida albicans in denture biofilm. The purpose of this study was to determine the in vitro effects of nicotine on coaggregation of C. Read More

    The essential oil of Allium sativum as an alternative agent against Candida isolated from dental prostheses.
    Rev Iberoam Micol 2017 Jun 1. Epub 2017 Jun 1.
    Facultad de Estomatología Universidad Autónoma de San Luis Potosí, Mexico. Electronic address:
    Background: The colonization of the surfaces of dental prostheses by Candida albicans is associated with the development of denture stomatitis. In this context, the use of fluconazole has been proposed, but its disadvantage is microbial resistance. Meanwhile, the oil of Allium sativum has shown an effect in controlling biofilm formation by C. Read More

    Fabrication of denture base materials with antimicrobial properties.
    J Prosthet Dent 2017 May 26. Epub 2017 May 26.
    Associate Professor, Faculty of Chemical Engineering, Biotechnology Research Center, Sahand University of Technology, Tabriz, Iran.
    Statement Of Problem: Acrylic resin denture base resins are colonized by oral and nonoral bacteria and Candida species. This reservoir of microorganism causes denture stomatitis, which can be implicated in some life-threating infections in older denture wearers.

    Purpose: The purpose of this in vitro study was to incorporate quaternized N,N-dimethylaminoethyl methacrylate (DMAEMA) monomer into a denture base resin and investigate its antimicrobial and mechanical properties. Read More

    Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on Candida albicans isolates from denture stomatitis patients.
    PLoS One 2017 11;12(5):e0176755. Epub 2017 May 11.
    Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago, Chile.
    Candida albicans biofilms play a key role in denture stomatitis, one of the most common oral pathologies in elderly people. Because biofilms are highly resistant to antifungals, new pharmacological strategies are needed. Aspirin and nitric oxide-donor molecules have both shown antibiofilm effects on C. Read More

    Prevalence of Chronic Erythematous Candidiasis in Lebanese Denture Wearers: a Clinico-microbiological Study.
    Mater Sociomed 2017 Mar;29(1):26-29
    Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
    Objective: Chronic erythematous candidiasis also known as denture-related stomatitis refers to inflammatory changes of the denture-bearing mucosa. The aim of this study was to evaluate the prevalence of chronic erythematous candidiasis in a Lebanese population using clinical and microbiological examinations.

    Materials And Methods: Ninety-eight patients wearing full acrylic maxillary denture (50 women and 48 men) were included in this study. Read More

    The antifungal effects and mechanical properties of silver bromide/cationic polymer nano-composite-modified Poly-methyl methacrylate-based dental resin.
    Sci Rep 2017 May 8;7(1):1547. Epub 2017 May 8.
    Department of Stomatology, Kunming General Hospital of Chengdu Military Command, Teaching Hospital of Kunming Medical University, Kunming, Yunnan, China.
    Poly-methyl methacrylate (PMMA)-based dental resins with strong and long-lasting antifungal properties are critical for the prevention of denture stomatitis. This study evaluated the antifungal effects on Candida albicans ATCC90028, the cytotoxicity toward human dental pulp cells (HDPCs), and the mechanical properties of a silver bromide/cationic polymer nano-composite (AgBr/NPVP)-modified PMMA-based dental resin. AgBr/NPVP was added to the PMMA resin at 0. Read More

    Improving practice guidelines for the treatment of denture-related erythematous stomatitis: a study protocol for a randomized controlled trial.
    Trials 2017 May 5;18(1):211. Epub 2017 May 5.
    Faculty of Dental Medicine, Université de Montréal, Montreal, QC, Canada.
    Background: Denture-related erythematous stomatitis (DES) is a chronic biofilm-mediated disease, affecting one in every three complete denture wearers. Antifungals are the treatment most commonly prescribed by oral health professionals, based on the belief that colonization by Candida spp. is the main cause of DES. Read More

    Early Adhesion of Candida albicans onto Dental Acrylic Surfaces.
    J Dent Res 2017 Apr 1:22034517706354. Epub 2017 Apr 1.
    1 Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, University College London, London, UK.
    Denture-associated stomatitis is a common candidal infection that may give rise to painful oral symptoms, as well as be a reservoir for infection at other sites of the body. As poly (methyl methacrylate) (PMMA) remains the main material employed in the fabrication of dentures, the aim of this research was to evaluate the adhesion of Candida albicans cells onto PMMA surfaces by employing an atomic force microscopy (AFM) single-cell force spectroscopy (SCFS) technique. For experiments, tipless AFM cantilevers were functionalized with PMMA microspheres and probed against C. Read More

    Equisetum giganteum influences the ability of Candida albicans in forming biofilms over the denture acrylic resin surface.
    Pharm Biol 2017 Dec;55(1):1698-1702
    c Department of Prosthodontics , Bauru School of Dentistry, University of São Paulo (USP) , Bauru , SP , Brazil.
    Context: Equisetum giganteum L. (Equisetaceae) is an endemic plant of Central and South America used in traditional medicine. Natural drugs have been frequently used in the treatment of a myriad of diseases, proving to be an alternative to synthetic chemicals, and have been intensively studied in the prevention of sicknesses, including oral diseases. Read More

    Effects of trimethylsilane plasma coating on the hydrophobicity of denture base resin and adhesion of Candida albicans on resin surfaces.
    J Prosthet Dent 2017 Apr 20. Epub 2017 Apr 20.
    Professor, Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, Mo.
    Statement Of Problem: Candida-associated denture stomatitis is the most common oral mucosal lesion among denture wearers. Trimethylsilane (TMS) plasma coating may inhibit the growth of Candida albicans on denture surfaces.

    Purpose: The purpose of this in vitro study was to investigate whether TMS plasma coatings can effectively reduce C albicans adhesion on denture base acrylic resin surfaces. Read More

    Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial.
    Evid Based Complement Alternat Med 2017 15;2017:8971746. Epub 2017 Mar 15.
    University of Brasilia (UnB), Brasilia, DF, Brazil.
    Our hypothesis tested the efficacy and safety of a mucoadhesive oral gel formulation of Brazilian propolis extract compared to miconazole oral gel for the treatment of denture stomatitis due to Candida spp. infection in older adults. Forty patients were randomly allocated in a noninferiority clinical trial into two groups. Read More

    Comparison of Candida Albicans Adherence to Conventional Acrylic Denture Base Materials and Injection Molding Acrylic Materials.
    J Dent (Shiraz) 2017 Mar;18(1):61-64
    Dept. of Prosthodontics, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
    Statement Of The Problem: Candida species are believed to play an important role in initiation and progression of denture stomatitis. The type of the denture material also influences the adhesion of candida and development of stomatitis.

    Purpose: The aim of this study was comparing the adherence of candida albicans to the conventional and injection molding acrylic denture base materials. Read More

    The antifungal activity and cytotoxicity of silver containing denture base material.
    Niger J Clin Pract 2017 Mar;20(3):290-295
    Department of Prosthodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
    Objective: Denture base materials are susceptible to fungal adhesion, which is an important etiological issue in the pathogenesis of denture stomatitis. The purpose of this in vitro study was to evaluate the antifungal activity and cytotoxicity of denture base material containing silver microparticles.

    Materials And Methods: The polymethyl methacrylate (PMMA) denture base material was used, and silver microparticles were added to the polymer powder in different concentrations by volume (0%, 0. Read More

    Oral mucosal lesions in a Chilean elderly population: A retrospective study with a systematic review from thirteen countries.
    J Clin Exp Dent 2017 Feb 1;9(2):e276-e283. Epub 2017 Feb 1.
    Gerontology Program, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
    Background: The oral examination is an essential part of the multidisciplinary medical care in elderly people. Oral mucosal lesions and normal variations of oral anatomy (OMLs) are very common in this people, but few studies have examined the frequency and prevalence of these conditions worldwide and less in Chile. The aim of this research was to evaluate the frequency of OMLs in a Chilean elderly population. Read More

    Diminished Antimicrobial Peptide and Antifungal Antibiotic Activities against Candida albicans in Denture Adhesive.
    Antibiotics (Basel) 2017 Feb 6;6(1). Epub 2017 Feb 6.
    Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA.
    The underlying causes of denture stomatitis may be related to the long-term use of adhesives, which may predispose individuals to oral candidiasis. In this study, we hypothesize that antimicrobial peptides and antifungal antibiotics have diminished anti-Candida activities in denture adhesive. To show this, nine antimicrobial peptides and five antifungal antibiotics with and without 1. Read More

    Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation.
    Arch Med Sci 2017 Feb 18;13(1):66-74. Epub 2016 Dec 18.
    Department of Dental Prophylaxis and Experimental Dentistry, Dental School, Jagiellonian University, Krakow, Poland; Oral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
    Introduction: The presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. While numerous studies have described links between periodontitis and endothelial dysfunction, little is known about the influence of denture-related stomatitis (DRS) on cardiovascular risk. Therefore, the aim of this study was to determine whether the treatment of DRS can lead to improvement of the clinical measures of vascular dysfunction. Read More

    Efficacy of photodynamic therapy in the inactivation of oral fungal colonization among cigarette smokers and non-smokers with denture stomatitis.
    Photodiagnosis Photodyn Ther 2017 Jun 24;18:50-53. Epub 2017 Jan 24.
    Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
    Objective: The aim was to assess the efficacy of antimicrobial photodynamic therapy (aPDT) in the inactivation of oral fungal colonization among cigarette smokers and non-smokers with denture stomatitis (DS).

    Methods: A questionnaire was used to gather demographic information. Clinical oral examination was performed to determine location of denture in the jaws and oral erythematous lesions. Read More

    Synthesis, Antifungal Activity, and Biocompatibility of Novel 1,4-Diazabicyclo[2.2.2]Octane (DABCO) Compounds and DABCO-Containing Denture Base Resins.
    Antimicrob Agents Chemother 2017 Apr 24;61(4). Epub 2017 Mar 24.
    Department of Prosthodontics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    The fungal pathogen Candida albicans causes a variety of oral infections, including denture stomatitis, which is characterized by inflammation of the oral mucosa in direct contact with dentures and affects a significant number of otherwise healthy denture wearers. While antifungal treatment reduces symptoms, infections are often recurrent. One strategy to address this problem is to incorporate compounds with fungicidal activities into denture materials to prevent colonization. Read More

    Repeated applications of photodynamic therapy on Candida glabrata biofilms formed in acrylic resin polymerized.
    Lasers Med Sci 2017 Apr 14;32(3):549-555. Epub 2017 Jan 14.
    Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP - Univ. Estadual Paulista, Avenida Francisco José Longo 777, São José dos Campos, 12245-000, São Paulo, Brazil.
    Previous studies have been suggested that photodynamic therapy (PDT) can be used as an adjuvant treatment for denture stomatitis. In this study, we evaluated the effects of multiple sessions of PDT on Candida glabrata biofilms in specimens of polymerized acrylic resin formed after 5 days. Subsequently, four applications of PDT were performed on biofilms in 24-h intervals (days 6-9). Read More

    The Denture-Associated Oral Microbiome in Health and Stomatitis.
    mSphere 2016 Nov-Dec;1(6). Epub 2016 Dec 28.
    School of Dentistry, University of Los Angeles at Los Angeles, Los Angeles, California, USA.
    While investigation of the microbiome on natural oral surfaces has generated a wealth of information, few studies have examined the microbial communities colonizing dentures and their relationship to oral health. To address this knowledge gap, we characterized the bacterial community associated with dentures and remaining teeth in healthy individuals and patients with denture stomatitis. The microbiome compositions of matched denture and tooth plaque samples of 10 healthy individuals and 9 stomatitis patients were determined by 16S rRNA gene pyrosequencing. Read More

    Inhibitory effects of Lactobacillus rhamnosus and Lactobacillus casei on Candida biofilm of denture surface.
    Arch Oral Biol 2017 Apr 31;76:1-6. Epub 2016 Dec 31.
    Department of Oral Microbiology and Immunology, College of Dentistry, Republic of Korea. Electronic address:
    Objective: Candida albicans biofilm is associated with denture-related stomatitis and oral candidiasis of elderly. Probiotics are beneficial bacteria and have antibacterial activity against pathogenic bacteria. The purpose of this study was to investigate the antifungal activity of various probiotics against C. Read More

    Candida albicans biofilm heterogeneity does not influence denture stomatitis but strongly influences denture cleansing capacity.
    J Med Microbiol 2017 Jan 6;66(1):54-60. Epub 2017 Feb 6.
    1​Oral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK 2​Institute of Healthcare Policy and Practice, School of Health, Nursing and Midwifery, University of the West of Scotland, UK.
    Approximately 20  % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability. Recently, there has been increasing evidence of C. Read More

    Cationic porphyrin-mediated photodynamic inactivation of Candida biofilms and the effect of miconazole.
    J Physiol Pharmacol 2016 Oct;67(5):777-783
    Department of Oral Pathology, University of Medical Sciences, Poznan, Poland.
    The formation of biofilms by Candida and the increasing resistance of Candida species to antifungals contribute to the high recurrence rates of denture stomatitis. This increase has stimulated an interest in antimicrobial photodynamic therapy (aPDT) as an alternative treatment. We examined the photoactivity of the porphyrin-based photosensitizer, TMP-1363, against biofilms of C. Read More

    EVALUATION OF DENTURE-RELATED FACTORS PREDISPOSING TO DENTURE STOMATITIS IN A LEBANESE POPULATION.
    Mater Sociomed 2016 Oct 17;28(5):392-396. Epub 2016 Oct 17.
    Department of Oral Pathology and Diagnosis, Faculty of Dentistry, Lebanese University, Beirut, Lebanon.
    Background: Denture stomatitis is a common fungal oral infection of multifactorial etiology. Denture-related factors such as denture's age, hygiene, night wearing and colonization by Candida albicans are known to predispose to denture stomatitis. The aim of this study was to evaluate these factors and their relationship with the occurrence of denture stomatitis in a Lebanese population. Read More

    Effect of sodium hypochlorite and Ricinus communis solutions on control of denture biofilm: A randomized crossover clinical trial.
    J Prosthet Dent 2017 Jun 4;117(6):729-734. Epub 2016 Dec 4.
    Professor, Department of Dental Materials and Prosthodontics, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. Electronic address:
    Statement Of Problem: The prevalence of complete edentulism remains high in the elderly, and previous data have shown that poor denture hygiene is common among patients with edentulism.

    Purpose: The purpose of this randomized crossover trial was to evaluate the efficacy of denture cleansers in terms of biofilm removal, antimicrobial action, and the remission of denture stomatitis.

    Material And Methods: Fifty denture wearers with denture stomatitis were instructed to brush their dentures (brush and soap) and to soak them (20 minutes/14 days) in 4 solutions, as follows: C (control), 0. Read More

    Correlation between age and gender in Candida species infections of complete denture wearers: a retrospective analysis.
    Clin Interv Aging 2016 21;11:1707-1714. Epub 2016 Nov 21.
    Department of Orthodontics, Institute of Dentistry, Jagiellonian University Medical College, Kraków, Poland.
    Aim: Denture-related stomatitis is a disorder that often affects denture wearers. The purpose of this study was to evaluate the intensity, genera, and frequency of yeasts in the oral cavity of complete denture wearers in terms of subject gender and age.

    Materials And Methods: Nine hundred twenty patients (307 males and 613 females) with complete upper dentures were selected for the study and divided into four age groups: ≤50 years, 51-60, 61-70, and >70 years. Read More

    Inflammatory papillary hyperplasia: A systematic review.
    Med Oral Patol Oral Cir Bucal 2017 Jan 1;22(1):e36-e42. Epub 2017 Jan 1.
    University Campus of Bellvitge, Pabellón de Gobierno, 2nd floor, office 2:29, Feixa Llarga, s/n 08907, L'Hospitalet de Llobregat, Barcelona, España,
    Introduction: Inflammatory papillary hyperplasia (IPH) is a benign lesion of the palatal mucosa. It is usually found in denture-wearers but also has been reported in patients without a history of use of a maxillary prosthesis use.

    Objectives: The aim of this study is to review the literature to assess the prevalence of denture stomatitis and inflammatory papillary hyperplasia and the etiological factors associated. Read More

    Multilocus sequence typing (MLST) analysis of Candida albicans isolates colonizing acrylic dentures before and after denture replacement.
    Med Mycol 2016 Dec 2. Epub 2016 Dec 2.
    Sir John Walsh Research Institute, University of Otago Faculty of Dentistry, Dunedin, New Zealand
    Yeast, in particular Candida albicans, are the principal fungal cause of denture stomatitis, and can also be present as a commensal in many individuals. Few studies, however, have examined oral retention of yeast strains over time. We analyzed the yeast present in saliva samples and from the dentures of 10 individuals colonized with yeast but with no signs of stomatitis, before new complete maxillary dentures were fitted and also at 1, 3, and 6 months after denture replacement. Read More

    An In-vitro Evaluation of Retention, Colonization and Penetration of Commonly Used Denture Lining Materials By Candida albicans.
    J Clin Diagn Res 2016 Oct 1;10(10):ZC84-ZC88. Epub 2016 Oct 1.
    Professor and Head, Deparment of Prosthodontics and Crown and Bridge, Maratha Mandal's NGH Institute of Dental Sciences and Research Centre , Belgaum, Karnataka, India .
    Introduction: Colonization of the surface by Candida albicans and related Candida species is one of the major concerns of denture lining materials.

    Aim: We evaluated retention, colonization and penetration of the four denture lining materials namely Molloplast B, Permaflex, GC Soft Liner and Ufi Gel Hard C by Candida albicans.

    Material And Methods: a) Evaluation of retention: Five test discs of each material with smooth surface on one side and rough on the other were prepared and surface roughness (Ra) was measured with profilometer. Read More

    Interventions for the Management of Denture Stomatitis: A Systematic Review and Meta-Analysis.
    J Am Geriatr Soc 2016 Dec 27;64(12):2539-2545. Epub 2016 Nov 27.
    Postgraduate Program in Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
    Objectives: To assess the effectiveness of different interventions for treating or preventing denture stomatitis (DS).

    Design: Systematic review.

    Setting: Randomized controlled trials (RCTs) comparing any agent or procedure prescribed to treat or prevent DS in adults. Read More

    Clinical characteristics of an allergic reaction to a polyether dental impression material.
    J Prosthet Dent 2017 Apr 27;117(4):470-472. Epub 2016 Oct 27.
    Assistant Professor, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany. Electronic address:
    Allergic and hypersensitivity reactions to dental impression materials may occur throughout dental treatment, with diverse manifestations from slight redness to severe pain and a burning mouth with total stomatitis. Patients are often unaware of these allergic reactions, which makes early identification of the cause almost impossible. In addition, symptoms usually begin after 24 hours and mostly in patients with a preexisting history of allergic responses. Read More

    Promise of Combining Antifungal Agents in Denture Adhesives to Fight Candida Species Infections.
    J Prosthodont 2016 Nov 21. Epub 2016 Nov 21.
    Department of Periodontics, College of Dentistry, The University of Iowa, Iowa City, IA.
    Purpose: Several complications may arise in patients wearing complete prosthetic appliances, including denture-associated infections and mucosal stomatitis due to Candida species. This study evaluated the activity of anti-Candida agents in denture adhesive and the cytotoxicities of these preparations for primary human gingival epithelial (GE) keratinocytes.

    Materials And Methods: The anti-Candida activities of antimicrobial peptides, antimicrobial lipids, and antifungal agents against C. Read More

    Prevalence of Oral Mucosal Disorders in Diabetes Mellitus Patients Compared with a Control Group.
    J Diabetes Res 2016 25;2016:5048967. Epub 2016 Oct 25.
    Department of Oral Medicine and Surgery, School of Dentistry, Complutense University, Madrid, Spain.
    Chronic hyperglycemia is associated with impaired wound healing and higher susceptibility to infections. It is unclear whether patients with diabetes mellitus (DM) present more oral mucosal disorders compared to control groups. The objectives were to compare (a) the prevalence rates of oral mucosal disorders in the DM and non-DM population and (b) the prevalence rates of specific disorders in the DM and non-DM population. Read More

    Denture Stomatitis and Candida Albicans in Iranian Population: A Systematic Review and Meta-Analysis.
    J Dent (Shiraz) 2016 Sep;17(3 Suppl):283-292
    School of Dentistry, Shiraz University of medical sciences, Shiraz, Iran.
    Statement Of The Problem: Denture stomatitis is the common form of oral candidiasis, which is seen in the form of diffused inflammation in the areas covered by dentures. Many primary studies report the prevalence of denture stomatitis and candida albicans among patients in the Iranian population; therefore, using meta-analysis is valuable for health policy makers.

    Purpose: The purpose of the present study is to determine the prevalence of denture stomatitis and candida albicans in Iran. Read More

    Role of antifungal medicaments added to tissue conditioners: A systematic review.
    J Prosthodont Res 2016 Oct 13;60(4):231-239. Epub 2016 Apr 13.
    Department of Restorative Dentistry, College of Dentistry, Taibah University, Madinah Al Munawwarah, Saudi Arabia. Electronic address:
    Purpose: The aim of this review is to investigate the current state of knowledge on the incorporation of antifungal agents into the tissue conditioners for the treatment of denture induced stomatitis.

    Study Selection: Studies reporting the incorporation of antifungal/antimicrobial agents in to tissue conditioners were included in the review. In order to search the studies on the topic "incorporation of antifungal agents in tissue conditioners for the treatment of denture induced stomatitis" ISI web of science, PubMed/MEDLINE, and Google-Scholar databases were searched from 1970 up to and including July 2015 using various keywords such as antifungal agents, tissue conditioners, Candida albicans, denture stomatitis, etc. Read More

    New denture adhesive containing miconazole nitrate polymeric microparticles: Antifungal, adhesive force and toxicity properties.
    Dent Mater 2017 Feb 10;33(2):e53-e61. Epub 2016 Oct 10.
    Department of Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil.
    Objective: The purpose of this study was to develop a new oral drug delivery system by incorporating polymeric miconazole nitrate (MN) microparticles on an experimental antifungal denture adhesive (DA).

    Methods: Spray drying Eudragit L-100 (E) and Gantrez MS-955 (G) MN-microparticles were incorporated in DA. DAE1, DAG1, DAEG1, DAE2, DAG2, DAEG2 groups were obtained from the combination of polymers used in MN-microparticles (E, G and EG) and concentration of MN into DA (1, for 1% and 2, for 2%). Read More

    Intraoral Device for Optimal Antifungal Delivery in a Rat Model.
    Curr Drug Deliv 2016 Oct 13. Epub 2016 Oct 13.
    Bauru School of Dentistry, University of São Paulo - Department of Prosthodontics Bauru, São Paulo, Brazil.
    Background: Antifungal agents incorporated into temporary denture resilient liners as drug carries and delivery have been suggested as an alternative treatment for denture stomatitis. However, to test the in vivo biocompatibility of this protocol, standardization of an intraoral device for optimal drug delivery is required.

    Objective: Standardized criteria were produced to adjust an acrylic intraoral device (IOD) for rats feasible for denture stomatitis treatment by sustained drug-delivery based on minimal inhibitory drug concentrations (MICs) of antifungals for Candida albicans biofilm. Read More

    A 10-year report from a multicentre randomised controlled trial: Immediate non-occlusal versus early loading of dental implants in partially edentulous patients.
    Eur J Oral Implantol 2016;9(3):219-230
    Purpose: To compare peri-implant bone and soft-tissue levels of immediate non-occlusally loaded versus non-submerged early loaded implants in partially edentulous patients 10 years after loading.

    Materials And Methods: Fifty-two patients were randomised in five Italian private practices: 25 in the immediately loaded group and 27 in the early loaded group. To be immediately loaded, single implants had to be inserted with a torque of at least 30 Ncm, and splinted implants with a torque of at least 20 Ncm. Read More

    Clinical Effectiveness of Aloe Vera in the Management of Oral Mucosal Diseases- A Systematic Review.
    J Clin Diagn Res 2016 Aug 1;10(8):ZE01-7. Epub 2016 Aug 1.
    Senior Lecturer, Department of Preventive and community Dentistry, New Horizon Dental College and Research Institute , Sakri, Bilaspur, India .
    Introduction: Aloe vera is well known for its medicinal properties which lead to its application in treating various diseases. Its use in treating oral lesions has not been much documented in literature.

    Aim: Although, systematic reviews on aloe vera and its extracts have been done earlier, but in relation to oral diseases this is the first systematic review. Read More

    Comparative assessment of the effectiveness of different cleaning methods on the growth of Candida albicans over acrylic surface.
    Contemp Clin Dent 2016 Jul-Sep;7(3):336-42
    Department of Prosthodontics and Crown & Bridge, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.
    Context: This study evaluated the efficacy of denture adhesive, cleanser, chlorhexidine, and brushing against Candida albicans biofilm developed on an acrylic surface and predicted the most effective, simple, and inexpensive way to maintain denture health, thereby preventing denture stomatitis.

    Aims: To find the best possible method for maintaining denture hygiene.

    Settings And Design: This retrospective analysis was conducted in the Guru Nanak Institute of Dental Sciences and Research, Kolkata, and this in vitro study was designed to minimize denture stomatitis among denture wearing population. Read More

    Effect of incorporating seed oils on the antifungal property, surface roughness, wettability, weight change, and glucose sorption of a soft liner.
    J Prosthet Dent 2017 Jan 1;117(1):178-185. Epub 2016 Aug 1.
    Professor, Department of Prosthodontics and Crown and Bridge and Implantology, Coorg Institute of Dental Sciences, Virajpet, Coorg, and Rajiv Gandhi University of Health Sciences, Bangalore, India.
    Statement Of Problem: The colonization of Candida albicans on soft liners causes the deterioration of material surface properties and denture stomatitis.

    Purpose: The purpose of this in vitro study was to investigate the effect of incorporating seed oil on the antifungal properties, surface roughness, wettability, weight changes, and glucose adsorption/absorption of a soft liner.

    Material And Methods: Centratherum anthelminticum, Ocimum sanctum Linn, and Linum usitatissimum seed oils were incorporated into a soft liner, and the diameter of the inhibition zone (DIZ) was calculated relative to the growth of C albicans at 24, 48, and 72 hours and 7 days. Read More

    Transcription Factors Efg1 and Bcr1 Regulate Biofilm Formation and Virulence during Candida albicans-Associated Denture Stomatitis.
    PLoS One 2016 25;11(7):e0159692. Epub 2016 Jul 25.
    Department of Oral and Craniofacial Biology, Dental School, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America.
    Denture stomatitis (DS) is characterized by inflammation of the oral mucosa in direct contact with dentures and affects a significant number of otherwise healthy denture wearers. The disease is caused by Candida albicans, which readily colonizes and form biofilms on denture materials. While evidence for biofilms on abiotic and biotic surfaces initiating Candida infections is accumulating, a role for biofilms in DS remains unclear. Read More

    [PHYSICAL AND MATHEMATICAL GROUNDS LANDFORMS BASIS PLATE DENTURES WHEN APPLYING THE COMPLEX METHOD OF PREVENTION OF PROSTHETIC STOMATITIS].
    Georgian Med News 2016 Jun(255):27-32
    Odessa National Medical University, Ukraine.
    Objective - to develop the form of the drug reservoir to hold the vegetable oils under the basis of the prosthesis. The research was conducted on the Bench PMMA samples. The comparison group consisted of smooth plate PMMA. Read More

    Effect of Antimicrobial Denture Base Resin on Multi-Species Biofilm Formation.
    Int J Mol Sci 2016 Jun 29;17(7). Epub 2016 Jun 29.
    State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China.
    Our aims of the research were to study the antimicrobial effect of dimethylaminododecyl methacrylate (DMADDM) modified denture base resin on multi-species biofilms and the biocompatibility of this modified dental material. Candida albicans (C. albicans), Streptococcus mutans (S. Read More

    Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation.
    Int J Pharm 2016 Aug 21;510(1):323-35. Epub 2016 Jun 21.
    Department of Prosthodontics, Medical University of Warsaw, Poland.
    The objective of this study was to obtain a material composite with antifungal properties for dentures to be used as an alternative protocol in denture stomatitis treatment and prevention. Denture stomatitis is still a clinical problem in patients particularly vulnerable to this disease. Composites of PMMA and doped ZnO-NPs (weight concentrations, 2. Read More

    In Vitro and In Vivo Antifungal Activity of Lichochalcone-A against Candida albicans Biofilms.
    PLoS One 2016 10;11(6):e0157188. Epub 2016 Jun 10.
    Herman Ostrow School of Dentistry, Division of Periodontology Diagnostic Sciences, Dental Hygiene and Biomedical Sciences, University of Southern California, Los Angeles, CA, United States of America.
    Oral candidiasis (OC) is an opportunistic fungal infection with high prevalence among immunocompromised patients. Candida albicans is the most common fungal pathogen responsible for OC, often manifested in denture stomatitis and oral thrush. Virulence factors, such as biofilms formation and secretion of proteolytic enzymes, are key components in the pathogenicity of C. Read More

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