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J Multidiscip Healthc 2021 14;14:1413-1422. Epub 2021 Jun 14.

Department of Pediatric Dentistry, University Clinic of Dentistry, Medical University Vienna, Vienna, Austria.

Introduction: Universities with dental schools are faced with complex problems during the COVID-19 pandemic. Dentistry students are at a higher risk of contracting infections, specifically COVID-19, due to direct contact with patients. The aim of this study was to assess the knowledge, perception and attitude regarding COVID-19 among dentistry students in Austria. Read More

BMJ Case Rep 2021 Jun 23;14(6). Epub 2021 Jun 23.

Oral and Maxillofacial Surgery, Townsville Hospital and Health Service, Townsville, Queensland, Australia.

Facial subcutaneous emphysema (SE) is an uncommon sequelae of dental procedures and often attributed to the use of high-speed air-driven handpieces during surgical extractions, forcing air through fascial spaces. Rarely have there been documented cases of patient-induced SE. In this case report, we present an 18-year-old woman who was referred to the emergency department with a 5-day history of progressive swelling and pain to her right cheek, following a prolonged, but simple extraction of tooth 18. Read More

Case Rep Med 2021 1;2021:9967555. Epub 2021 Jun 1.

Department of Otorhinolaryngology and Head and Neck Surgery, Zagreb School of Medicine, University Hospital Center "Sestre Milosrdnice", Zagreb, Croatia.

Background: COVID-19 is a disease caused by a new strain of coronavirus (SARS-COVID-19). The WHO first learned about this new virus on December 31, 2019, following a report on a group of cases of "viral pneumonia" in Wuhan, People's Republic of China, and declared a pandemic in March 2020. The disease was an almost complete unknown at the outset, but knowledge of its pathophysiology, clinical picture, and treatment options grew and developed rapidly. Read More

Kathmandu Univ Med J (KUMJ) 2020 Jul-Sept.;18(71):243-248

Department of Prosthodontist, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Background The fixed dental prosthesis are one of the most commonly used prosthesis which are difficult for cleansing in dental clinical practice especially the interproximal areas. As a result, periodontal disease most commonly develops in interproximal areas. The efficacy of using dental floss and interdental brushing in addition to tooth brushing reduce plaque and gingival inflammation. Read More

J Food Biochem 2021 Jun 21:e13830. Epub 2021 Jun 21.

Department of Pharmacology, The Blue Lab, Molecular Medicine and Toxicology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India.

Herbal tea of Lagerstroemia speciosa Pers., commonly known as banaba, has been traditionally used to treat various ailments including diabetes and obesity due to its antioxidant and anti-inflammatory efficacies. Drug-induced liver injury is a common cause of acute liver failure. Read More

J Oral Maxillofac Surg 2021 May 15. Epub 2021 May 15.

Assistant professor, Department of Oral Medicine and Radiology, Government Dental College and Hospital, Mumbai.

Purpose: Infiltration techniques are used as an adjuvant to regional anesthesia. In this study, we evaluated the efficacy of the superficial cervical plexus nerve block; as an alternative to local infiltration techniques; in the management of mandibular fractures and peri-mandibular space infections.

Methods: A prospective randomized controlled trial was conducted on 24 patients having either mandibular fractures or peri-mandibular space infections; and were scheduled for surgery under regional anesthesia (eg, inferior alveolar nerve block, long buccal nerve block). Read More

Allergy 2021 06 9;76(6):1813-1824. Epub 2021 Mar 9.

Dermatology Unit, Department of MedicalSpecialties, Arcispedale Santa Maria Nuova-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Background: Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID-19) pandemic.

Methods: A national registry, named DA-COVID-19 and involving 35 Italian dermatology units, was established in order to evaluate the impact of COVID-19 pandemic on the management of adult AD patients treated with systemic immunomodulant/immunosuppressive medications or phototherapy. Demographic and clinical data were obtained at different timepoints by teledermatology during COVID-19 pandemic, when regular visits were not allowed due to sanitary restrictions. Read More

Front Immunol 2021 2;12:617925. Epub 2021 Jun 2.

Department of Neonatology, Vest Children's Hospital Datteln, University Witten-Herdecke, Witten-Herdecke, Germany.

Group B Streptococcus (GBS) is a common intestinal colonizer during the neonatal period, but also may cause late-onset sepsis or meningitis in up to 0.5% of otherwise healthy colonized infants after day 3 of life. Transmission routes and risk factors of this late-onset form of invasive GBS disease (iGBS) are not fully understood. Read More

Front Microbiol 2021 2;12:676108. Epub 2021 Jun 2.

Robert Koch Institute, Unit 37: Nosocomial Infections, Surveillance of Antimicrobial Resistance and Consumption, Berlin, Germany.

Data on microbiological profiles in odontogenic infections are scarce. This study aimed to analyze the spectrum of pathogens and antimicrobial resistance in clinical isolates from dental and oral-maxillofacial clinical settings in Germany. We analyzed 20,645 clinical isolates (dental practices: = 5,733; hospitals: = 14,912) from patients with odontogenic infections using data (2012-2019) from the German (ARS) system. Read More

Int J Paediatr Dent 2021 Jul;31(4):528-538

Department of Pediatric Dentistry, Government Dental College and Hospital, Mumbai, India.

The COVID-19 pandemic has posed an extraordinary challenge to the world. Dental healthcare personnel are considered to be at high risk as they work in close proximity to the oral cavity of patients. New procedures of approach and management should be incorporated in different aspects of routine dental practice. Read More

Support Care Cancer 2021 Jun 18. Epub 2021 Jun 18.

Department of Surgery, Stomatology, Pathology and Radiology, University of Sao Paulo, Bauru School of Dentistry, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.

Objectives: To investigate the association of oral health condition with the occurrence of medication-related osteonecrosis of the jaw (MRONJ) in a cancer population.

Methods: A multicenter cross-sectional study was conducted with cancer patients exposed to bisphosphonates for at least 7 months. Dental and periodontal conditions were assessed by epidemiological indices. Read More

Int Dent J 2021 May 21. Epub 2021 May 21.

Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil.

Background: We evaluated and compared the cumulative incidence of confirmed COVID-19 cases between oral health professionals and the general population in Brazil.

Methods: Secondary data from notification of laboratory unconfirmed and confirmed cases of COVID-19 in the National data system for 41 epidemiological weeks were analysed and compared between oral health professionals (dentist + oral health technicians/assistants) and the general population. The cumulative incidences of COVID-19 were obtained by the ratio of the total number of confirmed cases to the total Brazilian population or the population of oral health professionals registered with the Federal Council of Dentistry and adjusted by age. Read More

BMC Oral Health 2021 06 18;21(1):313. Epub 2021 Jun 18.

Department of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

Background: Peri-implant mucositis and peri-implantitis are highly prevalent biofilm-associated diseases affecting the tissues surrounding dental implants. As antibiotic treatment is ineffective to fully cure biofilm mediated infections, antimicrobial modifications of implants to reduce or prevent bacterial colonization are called for. Preclinical in vivo evaluation of the functionality of new or modified implant materials concerning bacterial colonization and peri-implant health is needed to allow progress in this research field. Read More

Am J Dent 2021 Jun;34(3):127-131

Molecular Pathology Area, School of Dentistry, University of the Republic, Montevideo, Uruguay.

Purpose: To review diverse tests that could serve as a screening tool for the dental community to identify patients with potential COVID-19.

Methods: Detailed automated searches of Medline, PubMed and EBM Review, including ACP Journal Club, the Cochrane Controlled Trials Register, and the Cochrane Database of Systematic Reviews of Effectiveness from 2019 to 2020 were conducted. Real-time polymerase chain reaction (RT-PCR) or quantitative (q) RT-PCR and Western blot assays were excluded. Read More

Am J Dent 2021 Jun;34(3):123-126

Yankell Research Consultants, Inc., Moorestown, NJ, USA.

Purpose: To compare GUM ButlerWeave Mint waxed floss, Reach Mint waxed floss and Oral-B Glide Pro-Health Original waxed floss for the tensile strength parameters, load and elongation, and for their ability to reduce artificial plaque. Also examined is the potential relationship between the tensile strength physical attributes and floss efficacy.

Methods: For artificial plaque removal, floss products were placed around interproximal surfaces of artificial plaque-covered posterior-shaped teeth extending to a 60° angle. Read More

Heliyon 2021 Jun 28;7(6):e07168. Epub 2021 May 28.

Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Objectives: The present study aims to evaluate which studies evaluated the effectiveness of incorporating silver vanadate into dental materials and to analyze the influence of this incorporation on antimicrobial activity and material properties.

Data: This review was led by the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist and the JBI Briggs Reviewers Manual to answer the following question:Does the nanostructured silver vanadate decorate with silver particles present anti-microbial activity when incorporated into dental materials without altering its mechanical properties?

Source: An electronic search without restriction on the dates or languages was performed in PubMed/MEDLINE, Web of Science, Lilacs, Scopus, and Embase up until 2020. The search was specified and limited to the use of the words "nanostructured silver vanadate" in double quotation marks. Read More

Acta Odontol Latinoam 2021 Apr;34(1):63-70

Universidade Federal de Pelotas, Faculdade de Odontologia, Programa de Pós Graduação em Odontologia, Pelotas, Brasil.

This study evaluated the impact of COVID-19 on the endodontic treatment routine. It was a cross-sectional study using an online questionnaire applied to endodontists to collect information about practical modifications during endodontic treatment to protect professionals and patients against the COVID-19 outbreak. A total 1105 participants from Brazil participated in the survey. Read More

BMC Oral Health 2021 06 16;21(1):311. Epub 2021 Jun 16.

Stomatological Hospital, Southern Medical University and Guangdong Provincial Stomatological Hospital, 366 Jiangnan Avenue South, Guangzhou, 510260, China.

Background: Gingivitis is the most prevalent form of periodontal disease in children and adolescents, being strongly associated to some socioeconomic factors and oral health behaviours. This study aimed to assess the prevalence of gingivitis and its association with socio-demographic factors and oral health-related behaviours in children aged 12-15 years in Guangdong, Southern China.

Methods: A total of 7680 children were sampled using an equal-sized, stratified, multistage, random sampling method and clinically examined between December 2015 and April 2016. Read More

BMC Oral Health 2021 06 16;21(1):308. Epub 2021 Jun 16.

Voluntary Counseling and Testing Center, Shiraz University of Medical Science, Shiraz, Iran.

Background: The life expectancy of patients with Human Immunodeficiency Virus (HIV) has increased, but its oral manifestations can affect the Oral Health-Related Quality of Life (OHRQoL) of these patients. This study aimed to evaluate OHRQoL in HIV-infected patients and determine its related factors.

Methods: In this cross-sectional study, 250 HIV-infected patients were randomly selected from Shiraz Voluntary Counseling and Testing center in 2019. Read More

BMC Microbiol 2021 Jun 17;21(1):183. Epub 2021 Jun 17.

Department of Clinical Laboratory, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250021, Shandong, China.

Background: Lactobacilli are often recognized as beneficial partners in human microbial environments. However, lactobacilli also cause diseases in human, e.g. Read More

J R Coll Physicians Edinb 2021 06;51(2):199-207

Institute for Education in Medical and Dental Sciences, University of Aberdeen,

J R Coll Physicians Edinb 2021 06;51(2):168-172

Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK, Email:

Background: Simulation via Instant Messaging - Birmingham Advance (SIMBA) aimed to improve clinicians' confidence in managing various clinical scenarios during the COVID-19 pandemic.

Methods: Five SIMBA sessions were conducted between May and August 2020. Each session included simulation of scenarios and interactive discussion. Read More

Biosens Bioelectron 2021 Jun 5;190:113414. Epub 2021 Jun 5.

Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo, 060-8628, Japan; Innovative Research Centre for Preventive Medical Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan; Institute of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. Electronic address:

Antibody detection methods for viral infections have received broad attention due to the COVID-19 pandemic. In addition, there remains an ever-increasing need to quantitatively evaluate the immune response to develop vaccines and treatments for COVID-19. Here, we report an analytical method for the rapid and quantitative detection of SARS-CoV-2 antibody in human serum by fluorescence polarization immunoassay (FPIA). Read More

Minerva Dent Oral Sci 2021 06;70(3):128-130

College of Dentistry, Taibah University, Al Madinah, Saudi Arabia.

New Microbes New Infect 2021 Jul 23;42:100887. Epub 2021 Apr 23.

Department of Bacteriology and Virology, Semnan University of Medical Sciences, Semnan, Iran.

Regarding the relation of halitosis with oral infections and its effects on social relations between humans, the present study investigated the positive effects of probiotics on prevention or treatment of halitosis. The causative agents of halitosis are volatile sulphur compounds (VSCs), and halitosis is divided into oral and non-oral types according to the source of the VSCs. HS and CHSH are two main halitosis metabolites-produced following the degradation of proteins by bacteria in the mouth-however, CHSCH has a non-oral origin, and is a blood neutral molecule. Read More

Br Dent J 2021 06 11;230(11):760-764. Epub 2021 Jun 11.

Consultant Orthodontist, Orthodontic Clinic, Public Dental Health, Växjö, Sweden.

Orthodontic retention remains one of the great challenges in orthodontics. In this article, we discuss what is on the horizon to help address this challenge, including biological approaches to reduce relapse, treating patients without using retainers, technological developments, personalised medicine and the impact of COVID-19 on approaches to orthodontic retention. Read More

BMJ Case Rep 2021 Jun 11;14(6). Epub 2021 Jun 11.

Department of Medicine, East Sussex Healthcare NHS Trust, Eastbourne, East Sussex, UK.

Brainstem abscess is an uncommon occurrence in itself and an abscess in the medulla oblongata is even rarer. Although these abscesses have established association with head and neck infections, we report the first known case of medullary abscess that was found to be strongly associated with dental procedure. Important point to note is that a simple procedure like tooth extraction can predispose spread of infective seeding to distant sites. Read More

BMC Fam Pract 2021 Jun 11;22(1):112. Epub 2021 Jun 11.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, UK.

Background: Six percent of patients are allergic to penicillin according to their medical records. While this designation protects a small number of truly allergic patients from serious reactions, those who are incorrectly labelled may be denied access to recommended first line treatment for many infections. Removal of incorrect penicillin allergy may have positive health consequences for the individual and the general population. Read More

Rocz Panstw Zakl Hig 2021 ;72(2):185-191

Department of Public Health Dentistry, Rayat and Bahra Dental College and Hospital, Mohali, India.

Background: The second wave of Novel Coronavirus disease (COVID-19, SARS-CoV-2) is proving more disastrous than the first because of the new mutant stains. Under these circumstances, vaccination is the only effective solution that can save millions of lives across the globe.

Objectives: The present study was conducted to assess the attitude and acceptance/willingness of health care professionals (medical and dental) towards COVID-19 vaccine. Read More

Clin Oral Investig 2021 Jun 11. Epub 2021 Jun 11.

Department of Restorative Dentistry, Division of Endodontics, Piracicaba Dental School - State University of Campinas, UNICAMP, Av Limeira 901, Piracicaba, São Paulo, Brazil.

Objectives: This study aimed to detect the presence of specific bacteria and to evaluate the levels of lipopolysaccharides (LPS) and lipoteichoic acid (LTA) in symptomatic necrotic root canals associated with acute apical abscess (symptomatic group - GI). It also aimed to compare the findings with those presented by asymptomatic necrotic root canals (asymptomatic group - GII) in the different stages of the endodontic treatment.

Materials And Methods: Microbiological samples were collected from 20 root canals, including purulent collection from acute apical abscesses, before and after chemo-mechanical preparation (CMP) preparation (CMP) with chlorhexidine gel 2% and after 30 days of intracanal medication (ICM) with (Ca[OH]) + chlorhexidine. Read More