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    342 results match your criteria Demodicosis

    1 OF 7

    Successful treatment of refractory demodicosis and transient papules with a single dose of fluralaner in a dog with uncontrolled severe endocrine disease.
    J Vet Med Sci 2018 Mar 8. Epub 2018 Mar 8.
    Department of Veterinary Nursing, School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University.
    A 12-year-old female Shih-Tzu with hyperadrenocorticism and hypothyroidism developed concurrent refractory generalized demodicosis that did not respond to doramectin treatment. Although amitraz treatment was effective, the dog developed severe diabetes, which resulted in the cessation of amitraz and trilostane. Attempts to control the diabetes were unsuccessful, and its hyperadrenocorticism was left untreated, leading to the recurrence of demodicosis. Read More

    Papulopustular rosacea and rosacea-like demodicosis: two phenotypes of the same disease?
    J Eur Acad Dermatol Venereol 2018 Feb 25. Epub 2018 Feb 25.
    Université libre de Bruxelles (ULB) Institut de Recherche Interdisciplinaire en Biologie humaine et moléculaire (IRIBHM) & Service de Biostatistique et Informatique médicale (SBIM), Brussels, Belgium.
    Background: Papulopustular rosacea and rosacea-like demodicosis have numerous similarities but they are generally considered as two distinct entities, mainly because the causal role of the Demodex mite in the development of rosacea is not yet widely accepted. Several clinical characteristics are traditionally considered to differentiate the two conditions; for example, papulopustular rosacea is typically characterised by central facial papulopustules and persistent erythema, whereas small superficial papulopustules and follicular scales rather suggest rosacea-like demodicosis. However, none of these characteristics is exclusive to either entity. Read More

    [Demodex genus: colonizing parasites of healthy people or mites associated with ocular pathology?]
    Rev Argent Microbiol 2018 Feb 6. Epub 2018 Feb 6.
    Laboratorio de Parasitología, Hospital Nacional de Clínicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
    Demodex folliculorum and Demodex brevis are mites that are responsible for human demodicosis affecting skin and frequently linked to ocular diseasess. The aim of this work was to determine the association between Demodex sp. and eyelid and eyelash diseases and to establish the predisposing factors for acquiring this parasitic disease. Read More

    A field trial in Thailand of the efficacy of oral fluralaner for the treatment of dogs with generalized demodicosis.
    Vet Dermatol 2018 Feb 8. Epub 2018 Feb 8.
    Asian Veterinary Specialist Referral Center, 1F No.109 Section 4 Xin Yi road, Taipei, Taiwan.
    Background: Generalized demodicosis in dogs can be challenging to manage, especially in adult-onset cases.

    Hypothesis/objectives: This study evaluated the efficacy of oral fluralaner at the dose of 25-50 mg/kg for the treatment of canine generalized demodicosis.

    Animals: Client-owned dogs from Bangkok, Thailand, diagnosed with generalized demodicosis according to published criteria. Read More

    Efficacy and safety of sarolaner against generalized demodicosis in dogs in European countries: a non-inferiority study.
    Vet Dermatol 2018 Feb 8. Epub 2018 Feb 8.
    Zoetis, Veterinary Medicine Research and Development, 333 Portage St., Kalamazoo, MI, 49007, USA.
    Background: Treatment of canine demodicosis can be challenging; new treatments are always being sought.

    Objective: The efficacy of sarolaner was evaluated in comparison with a moxidectin/imidacloprid topical product against generalized demodicosis in dogs in a randomized, single-masked, multi-centre field study.

    Animals: Client-owned dogs were treated monthly with oral sarolaner (n = 53) or with weekly/monthly topical moxidectin/imidacloprid (n = 28). Read More

    Recurrent pyoderma and its underlying primary diseases: a retrospective evaluation of 157 dogs.
    Vet Rec 2018 Feb 1. Epub 2018 Feb 1.
    Small Animal Medicine Clinic, Centre of Clinical Veterinary Medicine, LMU Munich, Munich, Germany.
    Bacterial pyoderma is common in small animal practice. Usually there is an associated underlying disease, but little is known about the prevalence of underlying diseases in dogs with recurrent pyoderma. The aim of this study was to analyse the frequency of the different underlying diseases in dogs with recurrent pyoderma. Read More

    Doramectin in the treatment of generalized demodicosis.
    Vet Dermatol 2018 Apr 29;29(2):104-e41. Epub 2017 Dec 29.
    Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München, Veterinärstrasse 13, D-80539, München, Germany.
    Background: Generalized demodicosis is a common disease in dogs and doramectin has been reported as a successful treatment. Different treatment protocols using doramectin have not been previously evaluated.

    Objective: To evaluate whether oral administration of doramectin twice a week is more effective than administration by subcutaneous injection once a week. Read More

    Demodex canis targets TLRs to evade host immunity and induce canine demodicosis.
    Parasite Immunol 2018 Mar 7;40(3). Epub 2018 Jan 7.
    Department of Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan (DUVASU), Mathura, India.
    Widespread incidence of Demodex mites throughout the mammalian class and occasional serious and fatal outcomes in dogs warrant an insight into the host-parasite interface especially. Therefore, this study was aimed to unravel the interplay between innate immune response and canine demodicosis. The dogs diagnosed to have natural clinical demodicosis were allocated into two groups; dogs with localized demodicosis (LD) and with generalized demodicosis (GD). Read More

    Pityriasis Folliculorum: Response to Topical Ivermectin
    J Drugs Dermatol 2017 12;16(12):1290-1292
    Pityriasis folliculorum has been described as a dry type of rosacea with extensive proliferation of Demodex folliculorum in pilosebaceous follicles of the skin. This skin condition is frequently difficult to manage, with various treatment options showing mixed efficacy. Oral ivermectin, a macrocyclic lactone parasiticide with anti-inflammatory and anti-parasitic effects, is one of the leading treatment modalities for demodicosis. Read More

    A Clinical Scoring System for Diagnosis of Ocular Demodicosis.
    Med Sci Monit 2017 Dec 10;23:5862-5869. Epub 2017 Dec 10.
    Department of Ophthalmology, Uludag University School of Medicine, Bursa, Turkey.
    BACKGROUND Demodex may cause chronic and refractory blepharitis with associated ocular surface problems, and its diagnosis and treatment can be quite challenging. In this study, our aim was to assess the efficacy of tea tree oil in Demodex treatment on caucasian patients in an industrialized region of Turkey, and to develop a systematic scoring system for extremely accurate diagnosis in the absence of advanced facilities. MATERIAL AND METHODS Charts of 412 patients with blepharitis were reviewed. Read More

    Endosymbiosis and its significance in dermatology.
    J Eur Acad Dermatol Venereol 2018 Mar 28;32(3):347-354. Epub 2017 Dec 28.
    Department of Medical Biology, Faculty of Health Sciences, Warmia and Mazury University, Olsztyn, Poland.
    Proposed at the beginning of the twentieth century to explain the origin of eukaryotic organelles from prokaryotes, endosymbiosis is now medically defined by various interaction patterns between microorganisms and their residing hosts, best exemplified by the bacterial endosymbiont Wolbachia identified in arthropods and filarial nematodes, which can influence normal development, reproduction, survival and transmission of the hosts. Based on the transmission modes, vertical or horizontal, and the function of the endosymbionts, the host-symbiont dependence can be divided into primary or secondary. In dermatology, the role of endosymbionts in skin ectoparasitosis has aroused great interests in the past years. Read More

    Efficacy of lotilaner (Credelio™), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
    Parasit Vectors 2017 Nov 1;10(1):532. Epub 2017 Nov 1.
    ClinVet International (pty) Ltd, Uitsigweg, Bainsvlei, 9338, Bloemfontein, Republic of South Africa.
    Background: The oral systemic efficacy of lotilaner (Credelio™, Elanco) was evaluated against Demodex spp. in naturally infested dogs with generalized demodicosis.

    Methods: In this study, 10 dogs with clinical signs of generalized demodicosis and positive for Demodex spp. Read More

    Significant correlation between meibomian gland dysfunction and keratitis in young patients withinfestation.
    Br J Ophthalmol 2017 Oct 21. Epub 2017 Oct 21.
    Ocular Surface Clinic, Ocular Surface Center, Miami, Florida, USA.
    Aims: To report the clinical characteristics and correlation between meibomian gland dysfunction (MGD) and keratitis in young patients with ocular demodicosis.

    Methods: Observational case series of 60 patients younger than 35 years with ocular demodicosis, of which the diagnosis was based on microscopic counting ofandof epilated lashes. Severity of keratitis and MGD was graded by photography and meibography, respectively, in a masked fashion. Read More

    Demodicosis in two patients with a previous history of Langerhans cell histiocytosis.
    Pediatr Dermatol 2017 Nov 21;34(6):e299-e301. Epub 2017 Sep 21.
    Department of Dermatology, Hospital Sant Joan de Déu, Barcelona, Spain.
    Demodex mites are commensal organisms rarely found in healthy children. Human demodicosis can be classified as a primary or a secondary form. The secondary form in children usually affects severely immunodepressed children. Read More

    [Diagnostic criteria of demodex blepharitis].
    Zhonghua Yan Ke Za Zhi 2017 Sep;53(9):648-652
    Zhongshan Ophthalmic Centre, Sun Yat-sen University, State Key Laboratory of Ophthalmology, Guangzhou 510060, China.
    Demodex infestation is a common cause of blepharitis and now is drawing more and more attention from clinicians. Demodex mite is the most common age-related ectoparasite of human being and may be detected from asymptomatic normal population. Furthermore, the pathogenesis of demodicosis remains unclear. Read More

    Ocular Demodicosis as a Potential Cause of Ocular Surface Inflammation.
    Cornea 2017 Nov;36 Suppl 1:S9-S14
    *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Ocular Surface Center, Sun Yat-sen University, Guangzhou, China;†Ocular Surface Center, Miami, FL; and‡Tissue Tech Inc, Miami, FL.
    Among different species of mites, Demodex folliculorum and Demodex brevis are the only 2 that affect the human eye. Because demodicosis is highly age-dependent and can be found in asymptomatic adults, the pathogenicity of these mites has long been debated. In this study, we summarize our research experience including our most recent study regarding Demodex infestation as a potential cause of ocular inflammatory diseases. Read More

    Canine demodicosis: a retrospective study of a veterinary hospital population in California, USA (2000-2016).
    Vet Dermatol 2018 Feb 3;29(1):19-e10. Epub 2017 Sep 3.
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, 1 Garrod Drive, Davis, CA, 95616, USA.
    Background: Demodex spp. are cutaneous mites that cause clinical disease when present in increased numbers. There is an association in some dogs with underlying systemic disease or immunosuppressive medications. Read More

    Demodicosis Treatment with Systemic Ivermectin.
    Skinmed 2017 1;15(4):293-295. Epub 2017 Aug 1.
    Clínica Universitária de Dermatologia, Faculdade de Medicina de Lisboa, Clínica Universitária de Dermatologia, Faculdade de Medicina de Lisboa, Lisboa, Portugal.
    A 23-year-old white man presented to our dermatology department complaining of pruriginous and erythematous papulopustules on the right cheek that had developed 6 months previously. He had a history of chronic blepharitis, complicated by a recurrent hordeolum that had been treated with warm compresses and topical antibiotic ointment (chloramphenicol) for approximately 2 years. The patient had oily skin and atopy (allergic rhinitis) and did not experience photosensitivity or flushing or have previous exposure to immunosuppressants or topical/systemic corticosteroids. Read More

    Molecular Characterization and Analysis of 16S Ribosomal DNA in Some Isolates of.
    Iran J Parasitol 2017 Apr-Jun;12(2):224-229
    Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Demodicosis is one of the most prevalent skin diseases resulting from infestation bymites. This parasite usually inhabits in follicular infundibulum or sebaceous duct and transmits through close contact with an infested host.

    Methods: This study was carried from September 2014 to January 2016 at Tehran University of Medical Sciences, Tehran, Iran. Read More

    Human Permanent Ectoparasites; Recent Advances on Biology and Clinical Significance ofMites: Narrative Review Article.
    Iran J Parasitol 2017 Jan-Mar;12(1):12-21
    Dept. of Medical Biology, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland.
    Background: is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation betweenmites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Read More

    Demodex canis regulates cholinergic system mediated immunosuppressive pathways in canine demodicosis.
    Parasitology 2017 Sep 6;144(10):1412-1416. Epub 2017 Jun 6.
    Department of Veterinary Medicine,College of Veterinary Science and Animal Husbandry, DUVASU,Mathura - 281 001, U.P.,India.
    Demodex canis infestation in dogs remains one of the main challenges in veterinary dermatology. The exact pathogenesis of canine demodicosis is unknown but an aberration in immune status is considered very significant. No studies have underpinned the nexus between induction of demodicosis and neural immunosuppressive pathways so far. Read More

    Pneumocystis carinii infection with severe pneumomediastinum and lymph node involvement in a Whippet mixed-breed dog.
    J Vet Diagn Invest 2017 Sep 26;29(5):757-762. Epub 2017 May 26.
    Institute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
    A 3.5-y-old Whippet mixed-breed dog was presented with a history of respiratory distress, exercise intolerance, and generalized demodicosis. Hematologic alterations included marked leukocytosis and neutrophilia. Read More

    Afoxolaner and fluralaner treatment do not impact on cutaneous Demodex populations of healthy dogs.
    Vet Dermatol 2017 Oct 23;28(5):468-e107. Epub 2017 May 23.
    Cummings Veterinary Medical Center, Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA.
    Background: Fluralaner and afoxolaner are isoxazolines licensed for the treatment of flea and tick infestations. Isoxazolines have also shown efficacy for treatment of demodicosis. Nothing is known about the impact of these compounds on the populations of Demodex in healthy dogs. Read More

    Demodicosis in Pediatric Cancer.
    J Pediatr Hematol Oncol 2017 Jul;39(5):402-406
    *Princess Máxima Center for Pediatric Oncology †Department of Dermatology, University Medical Center-Wilhelmina Children's Hospital, Utrecht, The Netherlands.
    Demodicosis is a rare condition that most often occurs in immunocompromised patients. We here describe a boy with T-cell non-Hodgkin lymphoma who developed a facial papulopustular eruption just before finalizing T-cell non-Hodgkin lymphoma treatment. He was treated for several infectious diseases without improvement. Read More

    The use of oral fluralaner for the treatment of feline generalised demodicosis: a case report.
    J Small Anim Pract 2017 Aug 3;58(8):476-479. Epub 2017 May 3.
    Servizi Dermatologici Veterinari, Lovere, 24065, Italy.
    There is little agreement on the most effective and safest treatment for feline demodicosis. Protocols generally consist of long-lasting therapy courses based on rinses, subcutaneous injections, oral drug administration or repeated spot-on formulation and the efficacy of most of these is poorly documented. Many of these products have also been associated with adverse effects and may be difficult to administer in cats, leading to poor owner compliance and treatment failure. Read More

    Mite Density Determinations by Standardized Skin Surface Biopsy and Direct Microscopic Examination and Their Relations with Clinical Types and Distribution Patterns.
    Ann Dermatol 2017 Apr 24;29(2):137-142. Epub 2017 Mar 24.
    Department of Dermatology, Gachon University School of Medicine, Incheon, Korea.
    Background: Demodicosis is a parasitic skin disease caused bymites, and the determination of mite density per square centimeter is important to diagnose demodicosis. Standardized skin surface biopsy (SSSB) and direct microscopic examination (DME) are commonly used to determinemites density (Dd). However, no study has previously compared these two methods with respect to clinical types and distribution patterns of demodicosis. Read More

    The "red face": Not always rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):201-206. Epub 2016 Oct 27.
    Department of Dermatology, Andreas Syggros Hospital, University of Athens, 5, Dragoumi str, Athens, 16121, Greece. Electronic address:
    Facial erythema (the "red face") is a straightforward clinical finding, and it is evident even to the untrained eye; however, a red face does not represent a single cutaneous entity. It may be due to a plethora of distinct underlying conditions of varying severity, including rosacea, demodicosis, dermatomyositis, lupus erythematosus, allergic contact dermatitis, drug-induced erythema, and emotional blushing. In clinical practice, dermatologists do not encounter only one type of facial erythema but rather a number of different shades of red. Read More

    Prevalence of ocular demodicosis among patients at Tertiary Care Center, Bangkok, Thailand.
    Int J Ophthalmol 2017 18;10(1):122-127. Epub 2017 Jan 18.
    Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand; Excellence Center for Emerging Infectious Disease, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok 10330, Thailand.
    Aim: To determine the prevalence of ocular demodicosis by both microscopic examination and molecular detection among patients at King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok.

    Methods: One hundred individuals were enrolled in the study and were divided into five age groups. The meibomian gland dysfunction (MGD) score and qualities of cylindrical dandruff (CD) were also determined. Read More

    Do Demodex mites play a role in pterygium development?
    Med Hypotheses 2017 Jan 15;98:6-10. Epub 2016 Sep 15.
    Department of General Biology and Parasitology, Medical University of Warsaw, ul. Chałubińskiego 5, 02-004 Warsaw, Poland; W. Stefański Institute of Parasitology, Polish Academy of Sciences, ul. Twarda 51/55, 00-818 Warsaw, Poland. Electronic address:
    Numerous reports point to Demodex mites as the aetiology of certain eye and skin conditions, hence it is highly probable that infestation with these mites may also play a role in the aetiology and pathogenesis of pterygium. Therefore here we present a hypothesis: whether the presence of Demodex mites in eyelash hair follicles significantly correlates with the presence of pterygia, which could point to a potential role of these mites in the development of such lesions. We present preliminary data for supporting this hypothesis. Read More

    The effects of sebum configuration on Demodex spp. density.
    Turk J Med Sci 2016 Nov 17;46(5):1415-1421. Epub 2016 Nov 17.
    Department of Organic Agriculture, Tunceli Vocational School, Tunceli University, Tunceli, Turkey.
    Background/aim: Demodex spp. are ectoparasites living in the pilosebaceous units, which feed on the host's sebum and cellular proteins. The protective barrier of the skin consists of sebum secretion, moisture, and the acid mantle. Read More

    Clinical management of demodicosis in Ongole cattle.
    J Parasit Dis 2016 Dec 21;40(4):1311-1312. Epub 2015 Mar 21.
    Department of Veterinary Parasitology, College of Veterinary Science, Sri Venkateswara Veterinary University, Proddatur, 516360 Andhra Pradesh India.
    Demodicosis was diagnosed in a cattle based on dermatological lesions and examination of skin scrapings. The cattle had anaemia, leucocytosis, eosinophilia and neutrophilia. Cattle was treated with strepto penicillin, ivermectin, amitraz along with supportive therapy. Read More

    Non-dermatophyte Dermatoses Mimicking Dermatophytoses in Animals.
    Mycopathologia 2017 Feb 16;182(1-2):113-126. Epub 2016 Nov 16.
    UP Interactions Cellules Environnement, VetAgro Sup, Univ Lyon, 69280, Marcy l'Etoile, France.
    Dermatophytoses in animals are fungal diseases of the skin caused by dermatophyte fungi of the genus Microsporum or Trichophyton. Because the infection is generally follicular, the most common clinical sign is one or many circular areas of alopecia with variable erythema, scaling and crusting, and the primary differential diagnoses are follicular infections, such as bacterial folliculitis and demodicosis. Although dermatophyte folliculitis or ringworm is the most commonly observed lesion of dermatophytoses in animals, other presentations may be observed according to the host species and the dermatophyte involved: dermatophyte folliculitis or ringworm, scaling and crusting in dermatophytosis due to Microsporum persicolor, nodule in case of kerion or mycetoma, matted hairs, seborrheic dermatosis or miliary dermatitis in cats, generalized exfoliative dermatoses in dogs, cats and horses, superficial non-follicular pustules, papules and macules in the Devon Rex cat, pruritic dermatophytoses in dogs, cats and horses, and onychomycosis in dogs, cats and horses. Read More

    [Treatment options for chronic blepharitis considering current evidence].
    Ophthalmologe 2016 Dec;113(12):1082-1085
    Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.
    The goal of the treatment of chronic blepharitis lies in the reduction of inflammation, which can be achieved by warming, mechanical, and immunomodulatory measures as well as acaricide medication in cases with pathogenetically relevant demodicosis. Read More

    Ocular symptoms reported by patients infested with Demodex mites.
    Acta Parasitol 2016 Dec;61(4):808-814
    The purpose of this study was to determine subjective ocular symptoms occurring in patients infested with Demodex. The number of Demodex mites in the obtained material that correlated with the appearance of ocular symptoms was estimated. The study material were eyelashes collected from 1499 patients. Read More

    Loco-regional immune default: The immunocompromised district in human and comparative dermatology.
    Clin Dermatol 2016 Sep-Oct;34(5):654-7. Epub 2016 Apr 30.
    Department of Dermatology, Second University of Naples, Via Sergio Pansini 5, 80131 Naples, Italy.
    Lately, the innovative concept of an immunocompromised cutaneous district (ICD) has been introduced to explain why a previously injured cutaneous site may become in time a privileged location for the onset of opportunistic infections, tumors, and immune reactions. The injuring events capable of rendering a skin region a potential ICD are various, numerous, and most of the time identifiable by means of a careful clinical history. The reason that only a small minority of injured skin areas actually becomes ICDs, with subsequent opportunistic localization of a second and unrelated skin disorder, is presently unknown. Read More

    Two Consecutive Standardized Skin Surface Biopsies: An Improved Sampling Method to Evaluate Demodex Density as a Diagnostic Tool for Rosacea and Demodicosis.
    Acta Derm Venereol 2017 Feb;97(2):242-248
    Rue Franz Binjé no 8, BE-1030 Brussels, Belgium.
    Diagnosing papulopustular rosacea is not always straightforward; no specific diagnostic test is currently available. A high density of Demodex mites is consistently observed in this condition. This retrospective study assesses an improved method for evaluating Demodex density among 1,044 patients presenting to our dermatology practice. Read More

    Demodex phylloides infection in swine reared in a peri-urban family farm located on the outskirts of the Metropolitan Region of São Paulo, Brazil.
    Vet Parasitol 2016 Oct 8;230:67-73. Epub 2016 Jun 8.
    Biological Institute, Animal Health Research and Development Center, Av. Conselheiro Rodrigues Alves, 1252, Vila Mariana, CEP: 04014-002 São Paulo, SP, Brazil.
    This paper reports the occurrence of porcine demodicosis caused by the mite Demodex phylloides in hogs reared in a peri-urban family farm located in Francisco Morato, a municipality of the Metropolitan Region of São Paulo, capital city of the state of São Paulo, Brazil. In a parcel of forty Landrace - Large White cross hogs, approximately four months old, four animals presented severe skin lesions in the form of small nodules over their entire body, especially in the periocular region, snout, lower abdomen and flanks. Two hogs had to be euthanized for animal welfare reasons, which enabled post-mortem examination. Read More

    Clinical and histopathological evaluation of 16 dogs with T-zone lymphoma.
    J Vet Med Sci 2016 Sep 21;78(8):1237-44. Epub 2016 Apr 21.
    Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
    Clinical and histopathological characteristics of 16 dogs with nodal paracortical (T-zone) lymphoma (TZL) were evaluated. At initial examination, generalized lymphadenopathy was found in all dogs, and peripheral lymphocytosis was found in 10 of the 16 dogs. At initial diagnosis or during the disease course, 8 dogs (50%) were affected with demodicosis. Read More

    Efficacy of oral afoxolaner for the treatment of canine generalised demodicosis.
    Parasite 2016 24;23:14. Epub 2016 Mar 24.
    Clinvet International (Pty) Ltd, PO Box 11186, 9321 Universitas, South Africa.
    The efficacy of oral treatment with a chewable tablet containing afoxolaner 2.27% w/w (NexGard(®), Merial) administered orally was assessed in eight dogs diagnosed with generalised demodicosis and compared with efficacy in eight dogs under treatment with a topical combination of imidacloprid/moxidectin (Advocate(®), Bayer). Afoxolaner was administered at the recommended dose (at least 2. Read More

    Demodicosis in Chamois ( Rupicapra rupicapra subsp. rupicapra) in the Italian Alps, 2013-14.
    J Wildl Dis 2016 04 16;52(2):433-5. Epub 2016 Mar 16.
    1 Department of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2 - 56124 Pisa, Italy;
    We report demodicosis in five alpine chamois ( Rupicapra rupicapra subsp. rupicapra) from the Italian Alps that showed moderate crusts on the head and dorsal aspect of the trunk. We detected intramural folliculitis, moderate dermatitis, and T-lymphocytes and macrophages associated with Demodex spp. Read More

    Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis.
    Vet Parasitol 2016 May 4;222:62-6. Epub 2016 Mar 4.
    Zoetis, Veterinary Medicine Research and Development, Mercuriusstraat 20, Zaventem B-1930, Belgium.
    The efficacy of sarolaner (Simparica™, Zoetis) was evaluated against Demodex spp. in dogs with generalized demodicosis and against Otodectes cynotis (otodectic mange) in dogs with induced infestations. In the first study, 16 dogs with clinical signs of generalized demodicosis and positive for Demodex spp. Read More

    Demodex treatment in external ocular disease: the outcomes of a Tasmanian case series.
    Int Ophthalmol 2016 Oct 2;36(5):691-6. Epub 2016 Feb 2.
    Tasmanian Eye Institute, 36 Thistle St West, South Launceston, TAS, 7249, Australia.
    Demodex species (spp.) have previously been implicated in the pathogenesis of blepharitis. This study aims to correlate improvement in symptoms of external ocular disease with treatment of underlying Demodex spp. Read More

    Comparison of the efficacy of prednisone and cyclosporine for treatment of dogs with primary immune-mediated polyarthritis.
    J Am Vet Med Assoc 2016 Feb;248(4):395-404
    Objective: To compare efficacy between cyclosporine and prednisone for treatment of primary immune-mediated polyarthritis (IMPA) in dogs.

    Design: Randomized controlled clinical trial.

    Animals: 20 client-owned dogs with primary IMPA. Read More

    A rare clinical manifestation of spinulate demodicosis.
    Dermatol Online J 2016 Nov 15;22(11). Epub 2016 Nov 15.
    Department of Dermatology, Turgut Ozal University, Ankara, Turkey.
    Demodicosis is a chronic skin disease caused by Demodex mites such as Demodex folliculorum and Demodex brevis. Demodex mites live in pilosebaceous units and they are regarded as a part of the normal skin flora. Nevertheless, it has been suggested that the presence of five or more mites per cm² by the standardized skin surface biopsy technique could be considered as pathogenic. Read More

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