444 results match your criteria Demodicosis

Dermoscopy of papulopustular rosacea and comparison of dermoscopic features in patients with or without concomitant Demodex folliculorum.

Clin Exp Dermatol 2021 May 13. Epub 2021 May 13.

Section of Dermatology, Department of Health Sciences, Ospedale Policlinico San Martino, Genova, Italy.

Background: Dermoscopic findings of papulopustular rosacea include follicular plugs, white scales and follicle dilatation. Demodex tails and Demodex follicular openings are dermoscopic indicators mainly found in primary demodicosis and, less frequently, in rosacea.

Aim: The aim of this study was to describe the dermoscopic features of papulopustular rosacea and investigate the differential dermoscopic features between patients with and without concomitant Demodex infestation. Read More

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Which factors influence Demodex proliferation? A retrospective pilot study highlighting a possible role of subtle immune variations and sebaceous gland status.

J Dermatol 2021 May 9. Epub 2021 May 9.

Institut de Recherche Interdisciplinaire en Biologie humaine et moléculaire (IRIBHM), Université libre de Bruxelles (ULB), Brussels, Belgium.

Demodex folliculorum and brevis are commensal mites that live in low densities in human pilosebaceous follicles as part of the normal adult microbiota, but that give rise to demodicosis and, possibly, rosacea, when they proliferate excessively. This proliferation is favored by various factors, including age, marked immunosuppression, sebaceous gland hyperplasia, and hypervascularization-related factors. To study possible factors influencing mite proliferation, we explored the effects of different variables on Demodex densities (Dd) in a retrospective study of two groups of subjects selected on the basis of their clinical diagnosis: Demodex+, consisting of subjects with demodicosis or with centro-facial papulopustules suggesting rosacea (n = 844, mean Dd 263. Read More

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A Novel Lid Hygiene Detergent Successfully Eliminated Demodex Mites, a Common PRefractory Obstructive Meibomian Gland Dysfunction.

J Oleo Sci 2021 May 7. Epub 2021 May 7.

Department of Ophthalmology, Keio University School of Medicine.

Introduction: Demodex mites are microscopic arthropods that have been shown to be responsible for chronic blepharitis. Although many reports have demonstrated positive effects of lid hygiene on demodicosis, some have produced conflicting results. We retrospectively evaluated the effect of lid margin cleansing with a novel lid hygiene detergent, Eye Shampoo, in patients with ocular demodicosis. Read More

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Estimation of the prevalence and determination of risk factors associated with demodicosis in dogs.

J Adv Vet Anim Res 2021 Mar 6;8(1):116-122. Epub 2021 Mar 6.

Department of Medicine and Surgery, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.

Objectives: Demodicosis is a vital skin problem in dogs. The present study has determined the prevalence and associated risk factors of demodicosis in dogs and the response to treatment.

Materials And Methods: A total of 100 skin scrapings were collected from dogs having dermatological lesions brought to the Teaching and Training Pet Hospital and Research Center of Chattogram Veterinary and Animal Sciences University for treatment purpose. Read More

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Long-term follow-up of a single dose of fluralaner in nine dogs with demodicosis.

Vet Dermatol 2021 Apr 8. Epub 2021 Apr 8.

Dermatology, Veterinary Specialists Emergency Centre, 815 Ishigami Kawaguchi, Saitama, 333-0823, Japan.

Background: Long-term follow-up of oral fluralaner for canine demodicosis has not been demonstrated.

Objectives: A multicentre prospective open trial for the efficacy of oral fluralaner for the long-term (>12 month) management of canine demodicosis.

Animals: Client-owned dogs diagnosed with demodicosis at nine veterinary clinics. Read More

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Demodectic mange in threatened southern sea otters (Enhydra lutris nereis).

Vet Dermatol 2021 Mar 19. Epub 2021 Mar 19.

Marine Wildlife Veterinary Care and Research Center, California Department of Fish and Wildlife, 151 McAllister Way, Santa Cruz, CA, 95060, USA.

Background: Southern sea otters (Enhydra lutris nereis) rely on intact pelage for thermoregulation, and thus clinically significant demodicosis and associated alopecia can cause morbidity and death.

Hypothesis/objectives: This study aimed to describe lesions associated with follicular Demodex sp. infestation, estimate the prevalence and intensity of infestation, describe mite distribution across key anatomical regions, and assess mite presence or absence in relation to lesions and host risk factors. Read More

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First case of Phthirus pubis and Demodex co-infestation of the eyelids: a case report.

BMC Ophthalmol 2021 Mar 6;21(1):122. Epub 2021 Mar 6.

Department of Medical Oncology, Tongde hospital of Zhejiang Province, NO, 234, Gucui Road, Hangzhou, 310012, Zhejiang, China.

Background: Phthirus pubis is an obligate parasite of human beings. Demodex spp. is a much more common parasite of human beings. Read More

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Multiple Eyelid Signs are Suggestive of Infestation.

Clin Ophthalmol 2021 17;15:671-678. Epub 2021 Feb 17.

School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.

Purpose: To determine the signs associated with infestation in blepharitis patients and the rates of eyelash colonization among blepharitic patients and healthy individuals in Thailand.

Patients And Methods: This was a prospective, case-control clinical study. Eighty-three controls and 43 blepharitic patients were consecutively enrolled from Walailak University Hospital. Read More

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February 2021

Scale and Pustule on Dermoscopy of Rosacea: A Diagnostic Clue for Demodex Species.

Dermatol Pract Concept 2021 Jan 29;11(1):e2021139. Epub 2021 Jan 29.

Department of Biostatistics, Mustafa Kemal University Hatay, Turkey.

Background: mites are highly found in the skin of patients with rosacea. The diagnosis of can be made by standardized skin surface biopsy. Dermoscopy is a tool used in the noninvasive diagnosis of various dermatological diseases. Read More

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January 2021

The prevalence and risk factors of canine demodicosis: A retrospective long-term study of 409 cases.

Trop Biomed 2020 Sep;37(3):778-782

Far Eastern Federal University, Sukhanova, 8, Vladivostok, Primorsky Krai, 690091 Russia.

Canine demodicosis is a common skin disorder with multiple risk factors, including age and breed predisposition. There is relatively limited information about the risk factors for canine demodicosis in large canine populations. This retrospective case-control study was conducted by searching the electronic records of dogs with skin lesions for the presence of Demodex mites in skin scrapings. Read More

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September 2020

Successful treatment of otodemodicosis due to with sarolaner/selamectin topical solution in a cat.

Andrew C Simpson

JFMS Open Rep 2021 Jan-Jun;7(1):2055116920984386. Epub 2021 Jan 28.

Dermatology Department, VCA Aurora Animal Hospital, Aurora, IL, USA.

Case Summary: A 10-year-old spayed female Russian Blue cat was presented with a 3-month history of excessive otic discharge and scratching, only involving the right ear. Other than a moderate amount of ceruminous exudate present within the right ear on video-otoscopic examination, there were no other cutaneous abnormalities. The cat was deemed to be otherwise in good health based on physical examination and several laboratory profiles. Read More

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January 2021

Shared Makeup Cosmetics as a Route of Demodex folliculorum Infections.

Acta Parasitol 2021 Jan 19. Epub 2021 Jan 19.

Department of General Biology and Parasitology, Medical University of Warsaw, Chałubińskiego 5, 02-004, Warszawa, Poland.

Purpose: The aim of the study was to examine Demodex survival in makeup cosmetics, i.e., powder cream, mascara, and lipstick, and to determine whether cosmetics shared with others can be a source of D. Read More

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January 2021


Wiad Lek 2020 ;73(11):2482-2488


Objective: The aim: To conduct a marketing audit of the pharmaceutical market of Ukraine for acne and demodicosis medications.

Patients And Methods: Materials and methods: The study used marketing methods of analysis, survey, observation methods and reference literature - State Register of Medicines of Ukraine of the State Expert Center of the Ministry of Health of Ukraine.

Results: Results: As a result of marketing audit of retail audit data of pharmacy sales revealed that the leading sales in packaging is MNL benzylbenzoate, the share of which reached in different years from 45% to 32%, which was 1380902 and 647576 packages per year, respectively, in second place - metronidazole , benzoyl peroxide, zinc ointment and sulfur ointment respectively. Read More

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January 2021

Symptomatic vulvar demodicosis: A case report and review of the literature.

J Cutan Pathol 2020 Nov 26;47(11):1063-1066. Epub 2020 Aug 26.

Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Demodex folliculorum is a mite that commonly inhabits the pilosebaceous units of facial skin, particularly in a perioral and periorbital distribution. While typically an incidental and asymptomatic parasite, Demodex spp. are proposed to contribute to the pathogenesis of facial folliculitis, chronic blepharitis and papulopustular rosacea. Read More

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November 2020

Pediatric Demodicosis Associated with Gain-of-Function Variant in STAT1 Presenting as Rosacea-Type Rash.

J Clin Immunol 2021 Apr 6;41(3):698-700. Epub 2021 Jan 6.

Laboratory of Clinical Immunology, Inflammation and Allergy, Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca, Morocco.

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Potential Role and Significance of Ocular Demodicosis in Patients with Concomitant Refractory Herpetic Keratitis.

Clin Ophthalmol 2020 23;14:4469-4482. Epub 2020 Dec 23.

Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.

Purpose: To evaluate the role of Demodex infestation of the eyelids in patients with recurrent herpetic keratitis.

Patients And Methods: This is a retrospective and noncomparative case series. Twenty-seven patients with ocular demodicosis and recurrent herpetic keratitis under conventional treatments were enrolled. Read More

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December 2020

Massive Demodicosis of the Eyes in a Patient with Sjögren Syndrome: A Case Report.

Acta Parasitol 2020 Oct 31. Epub 2020 Oct 31.

Chair and Department of Biology with Genetics, Medical University of Lublin, Witolda Chodźki 4 Street 4, 20-093, Lublin, Poland.

Purpose: Demodex mites infestation, typically asymptomatic, is a problem for patients with weakened immune systems because it often takes the form of symptomatic, massive infection. The Demodex mites play an important role in the occurrence of a range of eye surface diseases such as Demodex blepharitis, Meibomian gland dysfunctions, conjunctivitis and corneal changes. The ocular infection is closely related to the systemic invasion. Read More

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October 2020

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

Dermatol Ther (Heidelb) 2020 Dec 23;10(6):1229-1253. Epub 2020 Oct 23.

, Rue Frans Binjé 8, 1030, Brussels, Belgium.

Rosacea is a common facial dermatosis but its definition and classification are still unclear, especially in terms of its links with demodicosis. Triggers of rosacea (ultraviolet light, heat, spicy foods, alcohol, stress, microbes) are currently considered to induce a cascading innate and then adaptive immune response that gets out of control. Recent histological and biochemical studies support the concept that this inflammatory response is a continuum, already present from the onset of the disease, even when no clinical signs of inflammation are visible. Read More

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December 2020

Dermoscopy in Monitoring and Predicting Therapeutic Response in General Dermatology (Non-Tumoral Dermatoses): An Up-To-Date Overview.

Enzo Errichetti

Dermatol Ther (Heidelb) 2020 Dec 8;10(6):1199-1214. Epub 2020 Oct 8.

Institute of Dermatology, "Santa Maria Della Misericordia" University Hospital, Udine, Italy.

Besides the well-known use in supporting the non-invasive diagnosis of non-tumoral dermatoses (general dermatology), dermoscopy has been shown to be a promising tool also in predicting and monitoring therapeutic outcomes of such conditions, with the consequent improvement/optimization of their treatment. In the present paper, we sought to provide an up-to-date overview on the use of dermoscopy in highlighting response predictor factors and evaluating therapeutic results in the field of general dermatology according to the current literature data. Several dermatoses may somehow benefit from such applications, including inflammatory conditions (psoriasis, lichen planus, dermatitis, granulomatous conditions, erythro-telangiectatic rosacea, Zoon balanitis and vulvitis, cutaneous mastocytosis, morphea and extra-genital lichen sclerosus), pigmentary disorders (vitiligo and melasma) and infectious dermatoses (scabies, pediculosis, demodicosis and viral warts). Read More

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December 2020

Prevalence of Ocular Demodicosis and Ocular Surface Conditions in Patients Selected for Cataract Surgery.

J Clin Med 2020 Sep 23;9(10). Epub 2020 Sep 23.

Department of General Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland.

The aim of the study was to analyze the prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery. Eyelashes from 73 patients selected for cataract surgery were evaluated at × 40 and × 100 magnification using light microscopy. The anterior segment was assessed with the slit lamp. Read More

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September 2020

Prevalence of Ocular Demodicosis in an Older Population and Its Association With Symptoms and Signs of Dry Eye.

Cornea 2020 Sep 21. Epub 2020 Sep 21.

Department of Ophthalmology, Miami Veterans Administration Medical Center, Miami, FL.

Purpose: To evaluate associations between Demodex and its symptoms and ocular surface parameters in individuals with dry eye (DE).

Methods: A cross-sectional study of 119 individuals with DE symptoms or signs, grouped by the presence of ocular demodicosis, was performed. All individuals filled out questionnaires and underwent an ocular surface examination. Read More

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September 2020

Demodex and eye disease: a review.

Clin Exp Optom 2021 Apr 1;104(3):285-294. Epub 2021 Apr 1.

École d'optométrie, Université de Montréal, Montreal, Québec, Canada.

Demodex is the most common parasite living on humans and yet little is understood about its pathogenicity with respect to the ocular surface. An increasing interest in Demodex over the past 20-years has increased our understanding of this mite and its pathogenetic role. This article begins with a review of the anatomy, life cycle, mode of transmission and advances in genetics that can distinguish between Demodex folliculorum and Demodex brevis, the only two Demodex species in humans. Read More

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Mites, caterpillars and moths.

J Dtsch Dermatol Ges 2020 08 9;18(8):867-880. Epub 2020 Aug 9.

Department of Dermatology and Venereology, University Medical Center, Rostock, Germany.

Besides conditions such as scabies and hypersensitivity to house dust mites, other diseases caused by mites and caterpillars tend to be more uncommon in everyday practice. Nevertheless, there is a broad spectrum of medically relevant disorders associated with these arthropods. Mites may act as parasites that infect or colonize the skin (e. Read More

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Comparison of the efficacy of tea tree () oil with other current pharmacological management in human demodicosis: A Systematic Review.

Parasitology 2020 12 10;147(14):1587-1613. Epub 2020 Aug 10.

Department of Medicine, Monash University, Clayton, Victoria, Australia.

Various treatments are found to be moderately effective in managing Demodex-related diseases except tea tree oil (TTO) and terpinen-4-ol (T4O), which showed superior miticidal and anti-inflammatory effects in numerous clinical studies. Their possible effects include lowering mite counts, relieving Demodex-related symptoms, and modulating the immune system. This review summarizes the current clinical topical and oral treatments in human demodicosis, their possible mechanisms of action, side-effects and resistance in treating this condition. Read More

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December 2020

Acute inflammatory Demodex-induced pustulosis in an immunocompetent patient related to topical steroid use.

Pediatr Dermatol 2020 Sep 29;37(5):985-986. Epub 2020 Jul 29.

Division of Dermatology, Department of Internal Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

Demodex spp. mites are a common colonizer of sebaceous adult skin. Though usually clinically insignificant, demodicosis may be associated with a wide spectrum of skin diseases in immunocompetent hosts, such as erythematotelangiectatic and papulopustular rosacea, Demodex folliculorum, and blepharitis. Read More

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September 2020

Ocular Demodex: a systematic review of the clinical literature.

Ophthalmic Physiol Opt 2020 07 21;40(4):389-432. Epub 2020 Jul 21.

Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne, Australia.

Purpose: There is increasing clinical and research interest in the potential contribution of Demodex to ocular surface disease. The aim of this systematic review was to summarise and synthesise current clinical evidence relating to the aetiology, diagnosis and treatment of ocular Demodex.

Recent Findings: A comprehensive literature search was performed in OVID Medline, OVID Embase, and clinical trial registries, for studies published between 1990 and August 2019, examining Demodex on the ocular surface. Read More

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Primary facial demodicosis as a health problem and aesthetic challenge: A case report.

J Cosmet Dermatol 2021 Feb 23;20(2):420-424. Epub 2020 Jun 23.

Chair and Department of Biology and Parasitology, Medical University of Lublin, Lublin, Poland.

Colonization of skin by Demodex mites developing as a single facial lesion with a limited range is diagnosed relatively rarely. The presence of this type of skin lesions may hinder and thus delay the diagnostic process and application of appropriate treatment. The persistent cosmetic defect on the face is extremely onerous/embarrassing to the patient and impedes normal functioning. Read More

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February 2021

A European field assessment of the efficacy of fluralaner (Bravecto) chewable and spot-on formulations for treatment of dogs with generalized demodicosis.

Parasit Vectors 2020 Jun 11;13(1):304. Epub 2020 Jun 11.

MSD Animal Health Innovation GmbH, Zur Propstei, 55270, Schwabenheim, Germany.

Background: Recent reports indicate that the isoxazoline compounds have the potential to provide safe and effective treatment of canine generalized demodicosis, a condition that has been traditionally difficult to cure. Controlled field studies are needed to confirm this potential. A study was therefore initiated to investigate the efficacy of a single oral or spot-on treatment with fluralaner, an isoxazoline, compared with multiple topical treatments with imidacloprid-moxidectin, in dogs naturally affected by generalized demodicosis. Read More

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Review of extralabel use of isoxazolines for treatment of demodicosis in dogs and cats.

J Am Vet Med Assoc 2020 Jun;256(12):1342-1346

Amitraz is presently the only FDA-approved treatment for demodicosis in dogs in the United States. Amitraz treatment involves a protracted course of administration and risks of severe adverse effects such as sedation, bradycardia, and respiratory depression, which are caused by activation of α-adrenergic receptors. Other treatment options include macrocyclic lactones and lime sulfur, but these products have varied efficacy and high risks of adverse effects. Read More

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