8,562 results match your criteria Delusional Disorder


Schizophrenia Related Hospitalizations - a Big Data Analysis of a National Hospitalization Database.

Psychiatr Q 2020 Jul 1. Epub 2020 Jul 1.

Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Rua Dr. Plácido da Costa, 4200 - 450, Porto, Portugal.

Schizophrenia is a mental disorder characterized by long hospitalizations and frequent need for chronic/acute psychiatric care. Hospitalizations represent a valuable quality of care indicator in schizophrenia patients. The aim of this study was to describe a nationwide perspective of schizophrenia related hospitalizations. Read More

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http://dx.doi.org/10.1007/s11126-020-09793-8DOI Listing

The role of dopamine dysregulation and evidence for the transdiagnostic nature of elevated dopamine synthesis in psychosis: a positron emission tomography (PET) study comparing schizophrenia, delusional disorder, and other psychotic disorders.

Neuropsychopharmacology 2020 Jul 1. Epub 2020 Jul 1.

Psychosis Studies Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

There have been few studies performed to examine the pathophysiological differences between different types of psychosis, such as between delusional disorder (DD) and schizophrenia (SZ). Notably, despite the different clinical characteristics of DD and schizophrenia (SZ), antipsychotics are deemed equally effective pharmaceutical treatments for both conditions. In this context, dopamine dysregulation may be transdiagnostic of the pathophysiology of psychotic disorders such as DD and SZ. Read More

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http://dx.doi.org/10.1038/s41386-020-0740-xDOI Listing

Successful penile replantation after complete amputation and 23 hours ischaemia time: the first in reported literature.

BMJ Case Rep 2020 Jun 29;13(6). Epub 2020 Jun 29.

Plastic Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Complete penile amputation is a rare and poorly documented injury with severe physical and psychosocial implications. Our institution presents a case of successful penile replantation following 23 hours of ischaemia time in a 34-year-old man with a history of paranoid schizophrenia who sustained a complete penile amputation during an act of deliberate self-harm. To the best of our knowledge, this is the longest documented ischaemia time for a successful penile replant in literature. Read More

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http://dx.doi.org/10.1136/bcr-2020-234964DOI Listing

Impact of attachment imagery on paranoia and mood: evidence from two single case studies.

Behav Cogn Psychother 2020 Jun 29:1-12. Epub 2020 Jun 29.

Psychology Department, University of Southampton, Shackleton Building, Highfield Campus, Southampton, SO17 1BJ, UK.

Background: Cognitive behavioural therapy (CBT) for psychosis currently yields modest outcomes and must be improved. Attachment imagery may be an effective means of reducing severity of paranoid beliefs and associated affect. Experimental studies have demonstrated these effects in non-clinical groups. Read More

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http://dx.doi.org/10.1017/S1352465820000351DOI Listing

Parkinsonian Syndrome with Frontal Lobe Involvement and Anti-Glycine Receptor Antibodies.

Brain Sci 2020 Jun 23;10(6). Epub 2020 Jun 23.

Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Atypical Parkinsonian syndromes with prominent frontal lobe involvement can occur in the 4R-taupathies progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Secondary forms of movement disorders may occur in the context of autoimmune encephalitis with antineuronal antibodies, such as anti-glycine receptor (anti-GlyR) antibodies, which are typically associated with Stiff-Person spectrum syndrome, or progressive encephalomyelitis with rigidity and myoclonus. Overlaps between neurodegenerative and immunological mechanisms have been recently suggested in anti-IgLON5 disease. Read More

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http://dx.doi.org/10.3390/brainsci10060399DOI Listing

Color Trails Test: A New Set of Data on Cognitive Flexibility and Processing Speed in Schizophrenia.

Front Psychiatry 2020 9;11:521. Epub 2020 Jun 9.

Department of Psychiatry, Pomeranian Medical University, Szczecin, Poland.

Background: Although schizophrenia patients have been reported to manifest deficits in cognitive flexibility and lower processing speed (measured with i.a., the Color Trails Test, CTT), there still remain a few matters that require further investigation. Read More

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http://dx.doi.org/10.3389/fpsyt.2020.00521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296107PMC

Association of With Schizophrenia: Findings From Two Independent Samples of Han Chinese Population.

Front Psychiatry 2020 25;11:446. Epub 2020 May 25.

The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.

Objectives: Schizophrenia (SZ) is a complex psychiatric disorder that has a strong genetic basis. Dystrobrevin-binding protein 1 () is one of the genes thought to be pivotal in regulating the glutamatergic system. Studies have suggested that variations in confer susceptibility to SZ and clinical symptoms. Read More

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http://dx.doi.org/10.3389/fpsyt.2020.00446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286384PMC

Factors Affecting the Help-Seeking Behaviours of Patients with Schizophrenia in Rural Cambodia.

Case Rep Psychiatry 2020 5;2020:8065058. Epub 2020 Jun 5.

Transcultural Psychosocial Organization Cambodia, Phnom Penh, Cambodia.

In low- and middle-income countries in Asia, the use of supernatural, religious, and magical approaches to mental illness is widespread. We aimed to document the help-seeking behaviours and barriers to effective mental healthcare in the case of a psychiatric patient in rural Cambodia. The present case report describes the pathway that a patient with schizophrenia utilised to receive effective treatment in a rural area. Read More

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http://dx.doi.org/10.1155/2020/8065058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293719PMC

Platelet glutamate dehydrogenase activity and efficacy of antipsychotic therapy in patients with schizophrenia.

J Med Biochem 2020 Jan;39(1):54-59

Federal State Budgetary Scientific Institution, Mental Health Research Centre, Laboratory of Neurochemistry, Moscow, Russia.

Background: Evaluation of possible relationship between platelet glutamate dehydrogenase (GDH) activity and mental state of schizophrenia patients after antipsychotic pharmacotherapy.

Methods: Patients (n = 50) with chronic paranoid schizophrenia (F20.0) initially in acute psychotic state were examined before and after a treatment course with antipsychotics. Read More

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http://dx.doi.org/10.2478/jomb-2019-0018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282235PMC
January 2020

The association of schizotypal traits with Prepulse Inhibition: a double approach exploration.

Cogn Neuropsychiatry 2020 Jun 15:1-13. Epub 2020 Jun 15.

Department of Psychiatry and Behavioural Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.

According to the , schizotypy is a personality trait present in the population in a continuous manner while the emphasises its extreme presentations. In this study we examined the relationship between sensorimotor gating, a core risk-index of the schizophrenia-spectrum, and four schizotypal factors in a dimensional-wise and a dichotomising-wise approach. Two-hundred and eighty-three participants were assessed with the Schizotypal Personality Questionnaire and were tested for Prepulse Inhibition (PPI). Read More

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http://dx.doi.org/10.1080/13546805.2020.1779679DOI Listing

Folie a deux in monozygotic twins with childhood trauma: A case report.

Asian J Psychiatr 2020 Jun 4;53:102192. Epub 2020 Jun 4.

Department of Psychiatry, Yenepoya Medical College, Mangaluru, 575018, India.

Folie a deux is a rare syndrome characterized by induction of a delusion in a susceptible person in close proximity with an individual with known delusional disorder. We report a rare case of monozygotic twins with induced delusional disorder in one of the twins. The twins had experienced childhood trauma in the form of emotional neglect and physical abuse by the father. Read More

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http://dx.doi.org/10.1016/j.ajp.2020.102192DOI Listing

The role of nicotinic cholinergic neurotransmission in delusional thinking.

NPJ Schizophr 2020 Jun 12;6(1):16. Epub 2020 Jun 12.

Laboratory of Molecular Neurobiology, Institute for Biomedical Research (BIOMED), Faculty of Medical Sciences, UCA-CONICET, Av. Alicia Moreau de Justo 1600, C1107AFF, Buenos Aires, Argentina.

Delusions are a difficult-to-treat and intellectually fascinating aspect of many psychiatric illnesses. Although scientific progress on this complex topic has been challenging, some recent advances focus on dysfunction in neural circuits, specifically in those involving dopaminergic and glutamatergic neurotransmission. Here we review the role of cholinergic neurotransmission in delusions, with a focus on nicotinic receptors, which are known to play a part in some illnesses where these symptoms appear, including delirium, schizophrenia spectrum disorders, bipolar disorder, Parkinson, Huntington, and Alzheimer diseases. Read More

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http://dx.doi.org/10.1038/s41537-020-0105-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293341PMC

Virtual reality based cognitive behavioral therapy for paranoia: Effects on mental states and the dynamics among them.

Schizophr Res 2020 Jun 8. Epub 2020 Jun 8.

University of Groningen, University Medical Center Groningen, Department of Psychiatry, the Netherlands; Parnassia Psychiatric Institute, The Hague, the Netherlands; Maastricht University, Department of Psychiatry and Neuropsychology, Maastricht, the Netherlands.

Background: Negative affective processes may contribute to maintenance of paranoia in patients with psychosis, and vice versa. Successful treatment may break these pathological symptom networks. This study examined whether treatment with virtual reality based cognitive behavioral therapy (VR-CBT) for paranoia influences momentary affective states, and whether VR-CBT changes the adverse interplay between affective states and paranoia. Read More

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http://dx.doi.org/10.1016/j.schres.2020.05.047DOI Listing

Tracing the Roots of Dementia Praecox: The Emergence of Verrücktheit as a Primary Delusional-Hallucinatory Psychosis in German Psychiatry From 1860 to 1880.

Schizophr Bull 2020 Jun 9. Epub 2020 Jun 9.

Virginia Institute of Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia/Virginia Commonwealth University, Richmond, VA.

While the roots of mania and melancholia can be traced to the 18th century and earlier, we have no such long historical narrative for dementia praecox (DP). I, here, provide part of that history, beginning with Kraepelin's chapter on Verrücktheit for his 1883 first edition textbook, which, over the ensuing 5 editions, evolved into Kraepelin's mature concepts of paranoia and paranoid DP. That chapter had 5 references published from 1865 to 1879 when delusional-hallucinatory syndromes in Germany were largely understood as secondary syndromes arising from prior episodes of melancholia and mania in the course of a unitary psychosis. Read More

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http://dx.doi.org/10.1093/schbul/sbaa039DOI Listing

An attachment perspective on the risk for psychosis: Clinical correlates and the predictive value of attachment patterns and mentalization.

Schizophr Res 2020 Jun 5. Epub 2020 Jun 5.

Department of Dynamic and Clinical Psychology, Sapienza University of Rome, Via degli Apuli, 1, 00185 Rome, Italy. Electronic address:

Background: In a longitudinal design, the present study examined: (a) the nature of attachment patterns and reflective functioning (RF) in individuals at ultra-high risk for psychosis (UHR); (b) the association between RF and subclinical psychotic symtoms; and (c) the psychosis-predictive value of attachment patterns, RF, and the interaction between these factors.

Method: The sample comprised 57 UHR subjects and 53 clinical controls (non-UHR). UHR subjects were followed over a mean period of 14 months (SD = 2. Read More

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http://dx.doi.org/10.1016/j.schres.2020.05.052DOI Listing

Do neurobiological differences exist between paranoid and non-paranoid schizophrenia? Findings from the bipolar schizophrenia network on intermediate phenotypes study.

Schizophr Res 2020 Jun 2. Epub 2020 Jun 2.

Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, United States of America; Department of Psychiatry, Harvard Medical School, Boston, MA, United States of America. Electronic address:

Subtypes of schizophrenia, constructed using clinical phenomenology to resolve illness heterogeneity, have faced criticism due to overlapping symptomatology and longitudinal instability; they were therefore dropped from the Diagnostic Statistical Manual-5. Cognitive and imaging findings comparing paranoid (P-SZ) and non-paranoid (disorganized, residual and undifferentiated; NP-SZ) schizophrenia have been limited due to small sample sizes. We assessed P-SZ and NP-SZ using symptomatology, cognition and brain structure and predicted that there would be few neurobiological differences. Read More

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http://dx.doi.org/10.1016/j.schres.2020.02.011DOI Listing
June 2020
3.923 Impact Factor

Psychotic-like experiences in Chinese children and adolescents: The effect of earthquake exposure, maltreatment and negative life events.

Early Interv Psychiatry 2020 Jun 4. Epub 2020 Jun 4.

Institute of Emergency Management and Post-Disaster Reconstruction, Sichuan University, Chengdu, China.

Aim: Psychotic-like experiences (PLEs) are common in adolescents who have experienced or are experiencing trauma. However, the potential relationships between exposure to a major earthquake, negative life events or maltreatment and PLEs in Chinese adolescents are poorly understood. Therefore, this study explored the prevalence of PLEs and the psychosocial correlates in adolescent earthquake survivors. Read More

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http://dx.doi.org/10.1111/eip.12976DOI Listing

Care-seeking as a proxy indicator of the mental health of elderly Brazilians.

Braz J Psychiatry 2020 Jun 1. Epub 2020 Jun 1.

Centro de Integração de Dados e Conhecimentos para Saúde (CIDACS), Salvador, BA, Brazil.

Objective: To assess a large set of metadata made public by the Brazilian Ministry of Health on older subjects who visited outpatient mental health services in Brazil from 2008 to 2012.

Methods: We extracted data from the Brazilian Unified Health System Information Technology Department (Departamento de Informática do Sistema Único de Saúde, DATASUS), then calculated rates of visits per population in each of the five regions of Brazil, using census data for each year. Finally, logistic regressions were performed with depressive disorders or dementias as dependent variables, controlled by age and year of visit, stratified by region. Read More

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http://dx.doi.org/10.1590/1516-4446-2019-0721DOI Listing

[The functional activity of neutrophils in paranoid schizophrenia and Alzheimer's disease].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(4):97-101

Gilyarovsky Psychiatric Hospita - the branch of Moscow Psychiatric Clinical Hospital No.4, Moscow, Russia.

Objective: To evaluate the radical-producing function of neutrophils in paranoid schizophrenia and Alzheimer's disease.

Material And Methods: The study included 40 patients with paranoid schizophrenia and 22 with Alzheimer's disease. To assess the functional activity of neutrophils, whole blood samples were analyzed using the chemiluminescent method with two-step cell stimulation. Read More

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http://dx.doi.org/10.17116/jnevro202012004197DOI Listing
January 2020

[A study of alexithymia in schizophrenia and some somatic diseases].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(4):36-40

Azerbaijan Medical University Baku, Azerbaijan Republi, Azerbaijan Medical University Baku, Azerbaijan Republic.

Objective: To study alexithymia in schizophrenia and some somatic diseases.

Material And Methods: The study included 60 patients with paranoid schizophrenia (ICD-10 F20.0), 55 hypertensive patients with primary heart disease (I11), 53 patients with chronic ischemic heart disease (I25) and 51 patients with insulin-dependent diabetes mellitus (E10). Read More

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http://dx.doi.org/10.17116/jnevro202012004136DOI Listing
January 2020

Don't worry, be happy: Protective factors to buffer against distress associated with psychotic experiences.

Schizophr Res 2020 May 27. Epub 2020 May 27.

University of Groningen, University Medical Center Groningen, University Center Psychiatry (UCP) Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, the Netherlands; Department of Research and Education, Friesland Mental Health Care Services, Leeuwarden, the Netherlands.

Background: Around 6-7% of the general population report psychotic experiences (PEs). Positive PEs (e.g. Read More

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http://dx.doi.org/10.1016/j.schres.2020.05.019DOI Listing

Cowden syndrome complicated by schizophrenia: A first clinical report.

Eur J Med Genet 2020 Aug 24;63(8):103959. Epub 2020 May 24.

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Patients with Cowden syndrome exhibit mucocutaneous lesions, hamartomatous polyposis of the gastrointestinal tract, and macrocephaly, often complicated by malignant tumors, such as breast, thyroid, and uterine cancers. Autism spectrum and epilepsy have been known as neuropsychiatric symptoms associated with Cowden syndrome; however, to the best of our knowledge, there is no report on cases complicated by schizophrenia. Here, we report a first case of Cowden syndrome complicated by schizophrenia. Read More

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http://dx.doi.org/10.1016/j.ejmg.2020.103959DOI Listing

Auditory Verbal Hallucinations in Schizophrenia: Mode of Onset and Disclosure.

J Nerv Ment Dis 2020 May 22. Epub 2020 May 22.

Mental Health Center Glostrup, University Hospital Copenhagen, Broendby.

Recent reviews on auditory verbal hallucinations (AVHs) advocate a qualitative and interdisciplinary research that not only is limited to single descriptive features, but also involves contextual issues and co-occurring psychopathology. In this study of mainly readmitted patients with the International Classification of Diseases, Tenth Revision, diagnosis of paranoid schizophrenia and experiencing AVH, we performed a qualitative, phenomenologically oriented interview study. The focus was on the beginning of hallucinatory experiences, time to disclosure of the symptom, and the context surrounding the disclosure. Read More

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http://dx.doi.org/10.1097/NMD.0000000000001179DOI Listing

Paranoia as a deficit in non-social belief updating.

Elife 2020 May 26;9. Epub 2020 May 26.

Department of Psychiatry, Connecticut Mental Health Center, Yale University, New Have, United States.

Paranoia is the belief that harm is intended by others. It may arise from selective pressures to infer and avoid social threats, particularly in ambiguous or changing circumstances. We propose that uncertainty may be sufficient to elicit learning differences in paranoid individuals, without social threat. Read More

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http://dx.doi.org/10.7554/eLife.56345DOI Listing

Othello Syndrome Secondary to Cerebral Tuberculoma: A Case Report.

Rev Colomb Psiquiatr 2020 Apr - Jun;49(2):116-120. Epub 2018 Oct 8.

Instituto Nacional de Salud Mental Honorio Delgado-Hideyo Noguchi, Lima, Perú; Universidad Peruana Cayetano Heredia, Lima, Perú. Electronic address:

Introduction: Othello syndrome, an eponym of Shakespeare's character, is a transnosological diagnostic term that designates a clinical picture characterised by the presence of delusions of infidelity with respect to a partner and that, consequently, can lead to typical jealousy attitudes and violent behaviour towards the partner. In its pure form, it corresponds to delusional disorder of infidelity, but it may also be secondary to brain organicity and drug use.

Methods: Case report and non-systematic review of the relevant literature. Read More

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http://dx.doi.org/10.1016/j.rcp.2018.09.001DOI Listing
October 2018

Recurrent Episodes of Paraphilic Behavior Possibly Associated With Olanzapine and Aripiprazole Treatment in a Patient With Schizophrenia.

Front Psychiatry 2020 20;11:318. Epub 2020 Apr 20.

Department of Psychiatry and Psychotherapy, Eberhard-Karls University of Tübingen, Tübingen, Germany.

Background: Hypersexual and paraphilic disorders have been frequently associated with concomitant psychiatric disorders, including schizophrenia. A growing number of published cases has recently indicated that hypersexual behavior may also arise in conjunction with treatment with second-generation antipsychotics. Although hypersexuality has been acknowledged as a possible side effect of antipsychotic treatment with partial dopamine agonists, including aripiprazole, only very few cases of olanzapine-associated hypersexuality have been reported in the literature. Read More

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http://dx.doi.org/10.3389/fpsyt.2020.00318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212450PMC

Theta-Burst Stimulation for Auditory-Verbal Hallucination in Very-Late-Onset Schizophrenia-Like Psychosis-A Functional Magnetic Resonance Imaging Case Study.

Front Psychiatry 2020 20;11:294. Epub 2020 Apr 20.

Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.

Background: Treating very-late-onset (>60 years) schizophrenia-like psychosis (VLOSLP) is challenging. Age-related factors in elderly individuals (e.g. Read More

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http://dx.doi.org/10.3389/fpsyt.2020.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212466PMC

Unravelling potential severe psychiatric repercussions on healthcare professionals during the COVID-19 crisis.

J Affect Disord 2020 08 16;273:422-424. Epub 2020 May 16.

Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, 170 Villarroel st, 12-0, 08036, Barcelona, Catalonia, Spain.. Electronic address:

The coronavirus disease 2019 (COVID-19) outbreak is putting healthcare professionals, especially those in the frontline, under extreme pressures, with a high risk of experiencing physical exhaustion, psychological disturbances, stigmatization, insomnia, depression and anxiety. We report the case of a general practitioner, without relevant somatic or psychiatric history that experienced a "brief reactive psychosis (298.8)" under stressful circumstances derived from COVID-19. Read More

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http://dx.doi.org/10.1016/j.jad.2020.05.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228876PMC

[Psychosis Associated with Herbal Products: Iatrogenic Delusional Disorder].

Acta Med Port 2019 Dec 23. Epub 2019 Dec 23.

Serviço de Psiquiatria. Clínica de Psiquiatria e Saúde Mental. Centro Hospitalar e Universitário de São João. Porto. Portugal.

Metabolic, toxic or structural brain changes may present as psychotic symptoms. Organic delusional disorders are characterized by the presence of delusional ideas with evidence of brain dysfunction. Iatrogenesis may be a cause of this dysfunction. Read More

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http://dx.doi.org/10.20344/amp.13135DOI Listing
December 2019

A network analysis of post-traumatic stress and psychosis symptoms.

Psychol Med 2020 May 18:1-8. Epub 2020 May 18.

Department of Clinical Psychology and Amsterdam Public Health Research, VU University, van der Boehorsttraat 7, 1081 BTAmsterdam, The Netherlands.

Background: Understanding the interplay between trauma-related psychological mechanisms and psychotic symptoms may improve the effectiveness of interventions for post-traumatic stress reactions in psychosis. Network theory assumes that mental health problems persist not because of a common latent variable, but from dynamic feedback loops between symptoms, thereby addressing the heterogeneous and overlapping nature of traumagenic and psychotic diagnoses. This is a proof-of-concept study examining interactions between post-traumatic stress symptoms, which were hypothesized to reflect trauma-related psychological mechanisms, and auditory hallucinations and delusions. Read More

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http://dx.doi.org/10.1017/S0033291720001300DOI Listing

Subclinical paranoid beliefs and enhanced neural response during processing of unattractive faces.

Neuroimage Clin 2020 Apr 25;27:102269. Epub 2020 Apr 25.

Translational Research Center, University Hospital of Psychiatry, University of Bern, Switzerland. Electronic address:

The perception of faces and consequent social inferences are fundamental for interpersonal communication. While facial expression is important for interindividual communication, constitutional and acquired features are crucial for basic emotions of attraction or repulsion. An emotional bias in face processing has been shown in schizophrenia, but the neurobiological mechanisms are unclear. Read More

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http://dx.doi.org/10.1016/j.nicl.2020.102269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226880PMC

Coronovirus infection as a novel delusional topic.

Schizophr Res 2020 May 8. Epub 2020 May 8.

Department of Psychiatry, Jimenez Diaz Foundation Hospital, Madrid, Spain; Department of Psychiatry, Madrid Autonomous University, Madrid, Spain. Electronic address:

Delusional topics tend to rapidly incorporate popular hot topical issues. Thus, the current coronavirus COVID-19 pandemic has rapidly reached delusional themes in patients with psychiatric disorders. Here we present the clinical case of a Spanish woman with bipolar disorder that included coronavirus infection in her delusional themes even faster than the real infection reached mainland Spain. Read More

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http://dx.doi.org/10.1016/j.schres.2020.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205660PMC

Moderators and mediators of antipsychotic response in delusional disorder: Further steps are needed.

World J Psychiatry 2020 Apr 19;10(4):34-45. Epub 2020 Apr 19.

Department of Psychiatry, University of Toronto, Toronto, ON M5P 3L6, Canada.

Delusional disorder (DD) has been traditionally considered a relatively rare and treatment-resistant psychotic disorder. In the last decade, increasing attention has focused on therapeutic outcomes of individuals affected by this disorder. The aim of this paper is to provide a synthesis of the literature addressing two very important questions arising from DD research: (1) For which patients with DD do antipsychotic medications work best (the moderators of response); and (2) What variables best explain the relationship between such treatments and their effectiveness (the mediators of response). Read More

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http://dx.doi.org/10.5498/wjp.v10.i4.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203082PMC

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum.

World Psychiatry 2020 Jun;19(2):151-172

Department of Psychology, University of Notre Dame, South Bend, IN, USA.

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary boundaries between psychopathology and normality, frequent disorder co-occurrence, heterogeneity within disorders, and diagnostic instability. This paper synthesizes evidence on the validity and utility of the thought disorder and detachment spectra of HiTOP. These spectra are composed of symptoms and maladaptive traits currently subsumed within schizophrenia, other psychotic disorders, and schizotypal, paranoid and schizoid personality disorders. Read More

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http://dx.doi.org/10.1002/wps.20730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214958PMC

A case of delusional parasitosis presented as shared psychotic disorder treated successfully with aripiprazole.

Authors:
Derya Canlı

Indian J Psychiatry 2020 Mar-Apr;62(2):219-220. Epub 2020 Mar 17.

Department of Psychiatry, Amasya University Sabuncuoglu Serefeddin Education and Research Hospital, Amasya, Turkey. E-mail:

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http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_285_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197836PMC

Capgras and Fregoli syndromes: delusion and misidentification.

Int Rev Psychiatry 2020 May 7:1-5. Epub 2020 May 7.

Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.

Capgras and Fregoli syndromes are two psychotic and complex conditions also known as Delusional Misidentification Syndromes (DMSs). Their description dates back to the beginning of XX century, and many explanatory models have been formulated through myths, psychoanalytical and psychological hypotheses, as well as neurobiological proposals. Even if DMSs are not fully considered in the modern diagnostic manuals, they still remain intriguing phenomena to be clinically observed and explained. Read More

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http://dx.doi.org/10.1080/09540261.2020.1756625DOI Listing

Cortisol and DHEAS Related to Metabolic Syndrome in Patients with Schizophrenia.

Neuropsychiatr Dis Treat 2020 22;16:1051-1058. Epub 2020 Apr 22.

Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russian Federation.

Background: Both dehydroepiandrosterone (DHEAS) and cortisol are secreted by the adrenal glands and may modulate metabolic syndrome (MetS), which often affects the health of patients with schizophrenia. The relationship between the serum levels of these hormones and MetS has not been established.

Purpose: In this pilot study, we investigated the serum levels in schizophrenia patients with and without MetS and compared them with those in healthy volunteers. Read More

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http://dx.doi.org/10.2147/NDT.S247161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184116PMC

Olfactory Reference Syndrome: A Case Report and Screening Tool.

J Clin Psychol Med Settings 2020 Apr 29. Epub 2020 Apr 29.

Department of Psychiatry, Indiana University School of Medicine, 355 W. 16th St., Suite 2800, Indianapolis, IN, 46202, USA.

Olfactory reference syndrome (ORS) is a lesser known disorder that is related to obsessive-compulsive disorder. ORS is the obsessional and inaccurate belief that one is emitting a foul odor leading to embarrassment or concern about offending others, excessive hygiene behaviors, and social avoidance that significantly interferes with daily functioning. Although ORS is rare, it is challenging to diagnose. Read More

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http://dx.doi.org/10.1007/s10880-020-09721-9DOI Listing

Reduction of family stress level through therapy of psychoeducation of skizofrenia paranoid family.

Enferm Clin 2020 Mar;30 Suppl 3:155-159

Nursing Science Program, Kendal College of Health Sciences, Indonesia.

Objective: This study aims to determine the effect of paranoid schizophrenia family psychoeducation therapy on family stress levels in treating paranoid schizophrenia patients.

Method: It was a quantitative research with quasi experimental methods with Pre-post test with control group. The stress questionnaire was taken from the Depression Anxiety Stress Scale 42 was used in data collection after it was tested for validity (r-count between 0. Read More

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http://dx.doi.org/10.1016/j.enfcli.2019.12.048DOI Listing

141 Moderating Perspectives of Long Acting Injectable Use of Antipsychotics: A Literature Review.

Authors:
Kathy Riedford

CNS Spectr 2020 Apr;25(2):289-290

Associate Professor, Director of Psychiatric Mental Health Nurse Practitioner Specialty.

Long acting injectable (LAI) antipsychotics are indicated for individuals suffering from schizophrenia, delusional disorder, schizoaffective disorder and bipolar disorder. Even though LAIs have traditionally been used for a subgroup of patients who were not compliant with oral treatments or who were a high risk to others, current trends are changing with increased options and availability of these treatments. A number of factors are implicated in the reversal of this trend including perspectives of patients and perspectives of providers. Read More

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http://dx.doi.org/10.1017/S1092852920000577DOI Listing

173 It Smells Fishy: A Case Report and Discussion of Olfactory Reference Syndrome.

Authors:
Shafi Lodhi

CNS Spectr 2020 Apr;25(2):310

Resident, Department of Psychiatry, University of Cincinnati, Cincinnati, OH.

Abstract: Background: Olfactory reference syndrome (ORS) is a psychiatric condition characterized by the belief that one is emitting a foul body odor. The earliest cases of this disorder were often labeled as variants of schizophrenia. There remains significant controversy over whether this condition represents a manifestation of other psychiatric conditions or if it is a unique disorder in its own right. Read More

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http://dx.doi.org/10.1017/S1092852920000899DOI Listing

Evidence for an interrelated cluster of Hallucinatory experiences in the general population: an incidence study.

Psychol Med 2020 Apr 22:1-10. Epub 2020 Apr 22.

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.

Background: Although hallucinations have been studied in terms of prevalence and its associations with psychopathology and functional impairment, very little is known about sensory modalities other than auditory (i.e. haptic, visual and olfactory), as well the incidence of hallucinations, factors predicting incidence and subsequent course. Read More

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http://dx.doi.org/10.1017/S0033291720000793DOI Listing

Why do people call crisis helplines? Identifying taxonomies of presenting reasons and discovering associations between these reasons.

Health Informatics J 2020 Apr 18:1460458220913429. Epub 2020 Apr 18.

Public Health Agency, UK.

The objective of this study is to identify the most common reasons for contacting a crisis helpline through analysing a large call log data set. Two taxonomies were identified within the call log data from a Northern Ireland telephone crisis helpline (Lifeline), categorising the cited reason for each call. One taxonomy categorised the reasons at a fine granular level; the other taxonomy used the relatively coarser International Classification of Diseases-10. Read More

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http://dx.doi.org/10.1177/1460458220913429DOI Listing

A case report on clozapine-induced ventricular ectopics: a fatal adverse drug reaction.

J Basic Clin Physiol Pharmacol 2020 Apr 17;31(3). Epub 2020 Apr 17.

Indo Soviet Friendship College of Pharmacy - Pharmacy Practice, Moga, Punjab, India.

Background Clozapine is one of the most efficacious antipsychotic drug used for the treatment-resistant schizophrenia; it is sometimes associated with serious adverse reactions like agranulocytosis, myocarditis, cardiac rhythm disturbances, etc. Case presentation A 30-year-old patient with a primary diagnosis of paranoid schizophrenia (ICD code - F20.05) was on regular prescription for 6 years. Read More

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http://dx.doi.org/10.1515/jbcpp-2019-0339DOI Listing

Challenging our beliefs about delusional disorder in late life.

Int Psychogeriatr 2020 Apr;32(4):423-425

Mayo Clinic, Department of Psychiatry and Psychology, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1017/S1041610219001352DOI Listing
April 2020
1.934 Impact Factor

The de Clérambault syndrome: more than just a delusional disorder?

Int Rev Psychiatry 2020 Apr 14:1-7. Epub 2020 Apr 14.

Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.

The de Clérambault syndrome, commonly known as erotomania, is a delusional disorder in which the patient is convinced that another person has fallen in love with him or her. The syndrome is more frequent in female patients, who usually believe that their lover is a man belonging to a higher social and economic class, or is married, unknown, or even imaginary or deceased person. The course of the syndrome is usually chronic, with serious problematic behavioural consequences, including stalking behaviours, such as repetitive calling, unexpected visits or continuous attempts to send gifts or letters. Read More

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http://dx.doi.org/10.1080/09540261.2020.1744536DOI Listing

Wanting to Forget: Intrusive and Delusional Memories from Critical Illness.

Case Rep Crit Care 2020 24;2020:7324185. Epub 2020 Mar 24.

Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

. Delusional and fearful memories after critical illness are observed in up to 70% of patients post critical illness. However, they often go unrecognized after patients leave the intensive care unit (ICU). Read More

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http://dx.doi.org/10.1155/2020/7324185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128039PMC

[Paranoia Querulans in the First Half of the 20th Century: The Case of Elsa Asenijeff (1867-1941) and the German Psychiatric Literature of that Time].

Psychiatr Prax 2020 Apr 8. Epub 2020 Apr 8.

Forschungsstelle für die Geschichte der Psychiatrie, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Medizinische Fakultät der Universität Leipzig, Leipzig, Deutschland.

Objective: The writer Elsa Asenijeff was placed under guardianship based on the diagnosis paranoia querulans in 1921. The aim of this study was to commemorate her case and to question how this clinical picture was understood at the time in order to contribute to the history of this little researched disorder.

Methods: We illustrate the essence of Asenijeffs forensic examinations and of the descriptions of paranoia querulans in selected German psychiatric literature of the beginning of the 20 century. Read More

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http://dx.doi.org/10.1055/a-1125-3183DOI Listing

Lunar cycle and psychiatric hospital admissions for schizophrenia: new findings from Henan province, China.

Chronobiol Int 2020 Mar 7;37(3):438-449. Epub 2020 Apr 7.

Psychiatry research center, Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing, China.

: Findings on the effect of the lunar cycle on mental illness are conflicting. We investigated the association between the lunar cycle and a number of psychiatric presentations of schizophrenia and determined which subtypes were susceptible to lunar phases.: We evaluated 13,067 patients admitted to Zhumadian Psychiatric Hospital between January 1, 2012, and December 31, 2017 (73 lunar cycles). Read More

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http://dx.doi.org/10.1080/07420528.2019.1625054DOI Listing