8,743 results match your criteria Delusional Disorder

Tailored intervention to prevent relapses and hospitalization in a migrant suffering from paranoid schizophrenia.

Oxf Med Case Reports 2021 Jun 18;2021(6):omab049. Epub 2021 Jun 18.

Medecins Sans Frontieres, Public Health, Brussels, Belgium.

Adherence issues combined with inequitable access to healthcare may increase the risk of discontinuation of care for undocumented migrants with severe mental health illness. An Ethiopian man with paranoid schizophrenia who relapsed several times after hospitalization was identified by a humanitarian outreach team in Brussels. The team built a relationship with him by offering him access to services including accommodation and mental health care. Read More

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Delusion of pregnancy for 21 years in an elderly woman: A case report and review of literature.

Ind Psychiatry J 2020 Jul-Dec;29(2):342-344. Epub 2021 Mar 15.

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Delusion of pregnancy (DOP) is a rare phenomenon especially in the elderly, with only 22 cases being reported. In this report, we present a case of a 74-year-old female with DOP and depressive disorder. In this case, a diagnosis of persistent delusional disorder was considered as the DOP persisted even after resolution of depressive symptoms with the use of antidepressants, antipsychotics, and electroconvulsive therapy. Read More

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Psychiatric and legal considerations in cases of Fetal Abduction by Maternal Evisceration.

J Forensic Sci 2021 Jun 22. Epub 2021 Jun 22.

The Forensic Panel, New York, NY, USA.

Fifteen cases of Fetal Abduction by Maternal Evisceration (FAMAE) reported to the National Center for Missing and Exploited Children during 1987-2011 outline the findings from a review of the forensic psychiatric considerations and legal course of each of the cases. Most offenders confessed to law enforcement within a short time of being placed under arrest in statements reflecting a continued effort to manage impressions and minimize culpability. Psychiatric assessment is invariably central to the legal disposition of FAMAE cases, as the defendant's goal is to diminish the perception of culpability/criminal responsibility and mitigate sentencing. Read More

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Impact of the COVID-19 Pandemic on Psychiatric Hospitalization in a Tertiary Care Hospital of Northern India.

Prim Care Companion CNS Disord 2021 Jun 17;23(3). Epub 2021 Jun 17.

Department of Psychiatry, Government Medical College and Hospital, Chandigarh, India.

To study the pattern of admissions in a psychiatry ward during the coronavirus disease 2019 (COVID-19) pandemic and compare the sociodemographic and clinical profiles of patients admitted in 2020 with admissions in 2019.

The case record files of an inpatient psychiatric unit from March 23 to September 22, 2019, and March 23 to September 22, 2020 were retrieved. Sociodemographic data, admission criteria of the patients, clinical diagnosis (as per criteria), duration of stay in the ward, and details of capacity assessment were assessed. Read More

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Analysis of Mental Health Disease Trends Using BeGraph Software in Spanish Health Care Centers: Case Study.

JMIR Med Inform 2021 Jun 16;9(6):e15527. Epub 2021 Jun 16.

Department of Signal Theory and Communications, and Telematics Engineering, University of Valladolid, Valladolid, Spain.

Background: In the era of big data, networks are becoming a popular factor in the field of data analysis. Networks are part of the main structure of BeGraph software, which is a 3D visualization application dedicated to the analysis of complex networks.

Objective: The main objective of this research was to visually analyze tendencies of mental health diseases in a region of Spain, using the BeGraph software, in order to make the most appropriate health-related decisions in each case. Read More

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Othello Syndrome: Delusional Disorder - Jealous Type ≠ Violence.

CNS Spectr 2021 Apr;26(2):160-161

University of Florida College of Medicine, Department of Psychiatry, Gainesville, FL, USA.

Background: Othello syndrome, also known as morbid jealousy, pathological jealousy, and conjugal paranoia, is a rare delusional disorder related to partner's infidelity. There are no large scale or comprehensive studies on delusional jealousy, and only few case reports and cases series leave delusional disorder jealous type (DDJT) largely unknown. Herein, we report a case of DDJT, its possible etiology and describe its characteristics, comorbidities, and interventions. Read More

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Domestic Mass Shooters: The Association With Unmedicated and Untreated Psychiatric Illness.

J Clin Psychopharmacol 2021 Jun 7. Epub 2021 Jun 7.

From the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA Department of Psychiatry, The Icahn School of Medicine at Mount Sinai Hospital, New York, NY Adjunct Clinical Faculty, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine Law Office of Michael Laurence, San Francisco, CA.

Background: Given the relative lack of psychiatric information and data on the perpetrators of US mass shootings, the aim of our study was to understand who these "mass shooters" were and whether they had a psychiatric illness. If so, were they competently diagnosed, and if so, were they treated with appropriate medication for their diagnoses before the violence?

Methods: Because a prospective study of diagnosis and treatment could not, for obvious reasons, be carried out, we designed a retrospective, observational study of mass shooters, defined as those who killed 4 or more people with firearms between 1982 and 2012 or who killed 3 or more people with firearms between 2013 and 2019 in the United States. We used the Mother Jones database-a database of 115 persons identified as committing a mass shooting in the United States between January 1982 and September 2019. Read More

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Burns in the Context of a Shared Psychotic Disorder in a Colombian Referral Centre: a Case Report.

Rev Colomb Psiquiatr 2021 May 31. Epub 2021 May 31.

Clínica Foscal Internacional, Santander, Colombia; Semillero de Innovación e Investigación Quirúrgica (SIIQ), Santander, Colombia.

Introduction: Shared paranoid disorder is characterised by the development of psychotic symptoms in people who have a close affective bond with a subject suffering from a mental disorder. This case is the first case of burn injuries reported in the context of this disorder.

Case: We describe a young couple, with a similar pattern of burns caused by contact with a griddle. Read More

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Increased risk for developing gambling disorder under the treatment with pramipexole, ropinirole, and aripiprazole: A nationwide register study in Sweden.

PLoS One 2021 1;16(6):e0252516. Epub 2021 Jun 1.

Department of Clinical Sciences Lund, Psychiatry, Faculty of Medicine, Lund University, Lund, Sweden.

Gambling Disorder (GD) has recently been reclassified from an impulse-control disorder to a behavioural addiction and, as in other addictive disorders, the dopaminergic reward system is involved. According to neuroimaging studies, alterations within the striatal dopaminergic signalling can occur in GD. However, the findings to date are controversial and there has been no agreement yet on how the reward system is affected on a molecular basis. Read More

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NGS-based mtDNA profiling could reveal genetic alterations in Schizophrenia.

Curr Top Med Chem 2021 May 21. Epub 2021 May 21.

Department of Psychiatry, University Hospital "Alexandrovska" - Sofia, address: 1 G. Sofisky Str. 1431, Bulgaria.

Background: Schizophrenia is a complex disease with a putative genetic background. It was hypothesized that impaired mitochondrial function due to genetic alterations in mitochondrial DNA (mtDNA) could contribute to neurological conditions, including mental disorders. The aim of the study was to find out possible pathogenic mutations and/or variants in mtDNA potentially related to schizophrenia development. Read More

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[Clinical presentations and therapy of polysubstance dependence in patients with schizophrenia].

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(4):63-69

Moscow Research and Practical Center on Addictions, Moscow, Russia.

Background: The article presents the results of a clinical therapeutic and follow-up study of patients with a 'dual diagnosis' (polysubstance dependence comorbid with schizophrenia: paranoid schizophrenia or schizotypal disorder).

Objective: To study clinical/dynamic changes of polysubstance dependence in patients with schizophrenia (paranoid schizophrenia, schizotypal disorder) and to evaluate the duration and quality of therapeutic remissions.

Material And Methods: Two hundred and sixty-six male patients, including 176 patients with dependence syndrome and 90 patients with both dependence syndrome and schizophrenia, were studied. Read More

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Persistent psychotic symptoms and neurocognitive deficits in borderline personality disorder.

Schizophr Res 2021 Jun 23;232:109-111. Epub 2021 May 23.

Department of Psychiatry and Medical Psychology, Faculty of Medicine, Universidad Complutense de Madrid, Spain; Biomedical Research Networking Consortium for Mental Health (CIBERSAM), Madrid, Spain. Electronic address:

Background: Persistent psychotic symptomatology might be present in a group of patients with borderline personality disorder (BPD) according to recent research findings.

Aims: Investigate whether psychotic symptoms could be associated to greater cognitive and functional impairment in BPD patients.

Method: In this observational, cross-sectional study (PI14/01449 and PI17/01023), we investigated the incidence of persistent psychotic symptoms in BPD patients and its association with specific neurocognitive impairments. Read More

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Transsexualism or psychotic disorder? A case study.

Psychiatr Pol 2021 Feb 28;55(1):71-83. Epub 2021 Feb 28.

Instytut Psychologii, Uniwersytet Śląski w Katowicach.

The aim of the paper is to analyze the case of a man suffering from paranoid schizophrenia who experiences delusions and hallucinations concerning gender change, and to present ashort overview of the literature. The data presented in the case study were collected during a clinical interview, in the six-month diagnostic process. The interview was partly structured; the battery of tests were also used: MMPI-2, SCID-I, SCID-II, IPP, MoCA, and WAIS-R. Read More

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February 2021

Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial.

Front Pharmacol 2021 29;12:614811. Epub 2021 Apr 29.

Youth Mental Health Team, Brain and Mind Centre, Faculty of Medicine and Health, Central Clinical School, The University of Sydney, Sydney, NSW, Australia.

Cannabidiol (CBD), a principal phytocannabinoid constituent, has demonstrated antipsychotic properties in recent clinical trials. While it has also been suggested a promising candidate for the treatment of neurodegenerative disorders, it failed to demonstrate efficacy in cognitive impairments associated with schizophrenia as an add-on treatment (600 mg/day for 6 weeks) in 18 chronically ill patients co-treated with a variety of psychopharmacologic drugs. Here, we report on the results of parallel-group, active-controlled, mono-therapeutic, double-blind, randomized clinical trial (CBD-CT1; ClinicalTrials. Read More

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Psychopathology and Dissociation among Boarding School Students in Eastern Turkey.

J Child Adolesc Trauma 2021 Jun 16;14(2):201-207. Epub 2021 Apr 16.

Department of Psychiatry, Koc University Hospital, Topkapi, Davutpasa Cd. No:4, 34010 Zeytinburnu, Istanbul, Turkey.

A subset of boarding schools for adolescents was established in 1993 in the rural sections of Eastern Turkey to provide equity in terms of availability of education. Even though these schools were beneficial in many respects, implementation of this institutional model gave rise to many challenges such as weaker relationships with parents and defiance of authority figures. Failure to develop a mature response to these challenges could lead to the development of psychopathologies such as depression, psychosis, and dissociation. Read More

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Othello syndrome in Parkinson's disease: a systematic review and report of a case series.

Neurol Sci 2021 May 12. Epub 2021 May 12.

Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.

Introduction: Psychosis in Parkinson's disease (PD) is common and consists of hallucinations, illusions, and delusions. Among the latter, delusional jealousy, also named Othello syndrome (OS), might impair the quality of life of both patients and their partners. We aimed to perform a systematic review and report a series of PD patients presenting with OS. Read More

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Psychotic-like experiences? Trajectories and typologies of hallucinations and delusions from early adolescence to early adulthood in a population-based sample of Irish youth.

Ir J Psychol Med 2021 May 10:1-16. Epub 2021 May 10.

Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.

Objectives: Hallucinations and delusions that occur in the absence of a psychotic disorder are common in children and adolescents. Longitudinal phenomenological studies exploring these experiences are notably lacking. The objective of the current paper was to explore the phenomenology and characteristics of hallucinations and delusions from early adolescence to early adulthood. Read More

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Neural and Molecular Contributions to Pathological Jealousy and a Potential Therapeutic Role for Intranasal Oxytocin.

Front Pharmacol 2021 20;12:652473. Epub 2021 Apr 20.

The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.

Romantic jealousy, especially in its pathological form, is a significant contributor to both domestic abuse, including partner sexual coercion and even murder, although relatively little research has been conducted on it. Both obsessive and delusional forms have been identified although only the latter is currently recognized as a pathological disorder. Studies in both clinical and healthy populations have identified altered fronto-striatal responsivity as being associated primarily with romantic jealousy and to date drug based treatments have targeted both dopaminergic and serotonergic systems. Read More

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The Mental Status in Patients with Diabetes Mellitus Admitted to a Diabetes Clinic After Presenting in the Emergency Room: The Application of the SCL-90 Scale.

Diabetes Metab Syndr Obes 2021 28;14:1833-1840. Epub 2021 Apr 28.

Department of Internal Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

Background: Diabetes mellitus (DM) is one of the most serious public health problems, involving increasing costs worldwide. The mental state of a person with DM is varied and ever-changing, such as stress, the pressure to always do everything by the book, sadness, anger, and even denial of the disease, all these are feelings patients with DM will experience throughout their life.

Aim: The aim of our study was to assess the presence of mental and psychiatric disorders (anxiety, depressive states, paranoid ideation, phobia, obsessive-compulsive disorder) in a group of patients with DM after hospitalization in the Clinic for Diabetes, Nutrition, and Metabolic Diseases, for various exacerbations of the underlying condition, looking for possible correlations with other cardiovascular risk factors. Read More

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[Hiperfrequency in mental health hospital emergencies: case-control study.]

Rev Esp Salud Publica 2021 May 4;95. Epub 2021 May 4.

Hospital Universitario Central de Asturias. Servicio de Salud del Principado de Asturias. Oviedo. España.

Objective: To ensure the efficiency of the operation of the Emergency Department, specific mental health studies are needed. The purpose of the study was to identify and quantify the sociodemographic, clinical and organizational factors associated with the hyperfrequency of hospital Mental Health emergency departments in the three central areas of Asturias.

Methods: A retrospective case-control study was carried out. Read More

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Pseudocyesis Leading to Folie-à-Deux.

J Neurosci Rural Pract 2021 Apr 24;12(2):419-423. Epub 2021 Mar 24.

Department of Psychiatry, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.

Pseudocyesis or false belief of pregnancy is the emergence of classical manifestations of pregnancy-nausea, breast enlargement and pigmentation, abdominal distention, amenorrhea, and labor pains-in a nonpregnant woman. It is a multifactorial disease and its development is influenced by many different elements such as neuroendocrine, social, psychodynamic, and cultural issues. "Folie-à-deux," is shared psychotic disorder, describes a syndrome in which delusion is transferred to another person who is more susceptible. Read More

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Delusion progression process from the perspective of patients with psychoses: A descriptive study based on the primary delusion concept of Karl Jaspers.

PLoS One 2021 27;16(4):e0250766. Epub 2021 Apr 27.

Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan.

Background: Delusion occupies an important position in the diagnosis and treatment of patients with psychoses. Although Karl Jaspers' concept of the primary delusion (PD) is a key hypothesis in descriptive phenomenology concerning the primordial experience of delusion, to our knowledge it has not been verified in empirical studies of patients with psychosis, and the relationship between PDs and fully developed delusions remains unclear.

Methods: The subjects were 108 psychiatric patients diagnosed with DSM-IV schizophrenia or schizoaffective disorder who had persisting delusions. Read More

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Evaluation of the Executive Functioning and Psychological Adjustment of Child-to-Parent Offenders: Epidemiology and Quantification of Harm.

Front Psychol 2021 9;12:616855. Epub 2021 Apr 9.

Departamento Análisis e Intervención Psicosocioeducativa (AIPSE), Universidad de Vigo, Vigo, Spain.

With the aim of ascertaining if child-to-parent offenders have impairments in the executive functions and psychological maladjustment, and to quantify the potential harm and epidemiology, a field study was designed. As for this, 76 juvenile offenders sentenced for child-to-parent violence were assessed in executive functions (Stroop tasks) and psychological adjustment (Minnesota Multiphasic Personality Inventory-Adolescent, MMPI-A). The results showed valid responses for 75 juveniles and that data were not generally biased in line with defensiveness or malingering (differential diagnosis in justice juvenile evaluations). Read More

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Relationship between cannabis use and psychotic experiences in college students.

Schizophr Res 2021 May 19;231:198-204. Epub 2021 Apr 19.

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA.

Background: Emerging data suggest cannabis use is a component cause of psychotic disorders; however, the sequence of processes accounting for this association is poorly understood. Some clues have come from studies in laboratory settings showing that acute cannabis intoxication is associated with subclinical hallucinations and delusional thinking, i.e. Read More

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Excited Catatonia - A Delayed Neuropsychiatric Complication of COVID-19 Infection.

Cureus 2021 Mar 15;13(3):e13891. Epub 2021 Mar 15.

Department of Psychiatry, Burrell College of Osteopathic Medicine, Las Cruces, USA.

An increasing number of patients have been presenting with neuropsychiatric signs and symptoms associated with coronavirus disease (COVID-19). We present a case of a 69-year-old female with no prior psychiatric history who was brought to the emergency department due to bizarre behavior and paranoid thoughts for four to six weeks, worsening over the last two weeks. Psychiatric evaluation found that the patient had extreme restlessness and agitation, poor eye contact, paranoid delusions, visual hallucinations, and a flat affect with stereotypic repetition of speech and loose associations. Read More

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An active inference perspective on the negative symptoms of schizophrenia.

Lancet Psychiatry 2021 Apr 15. Epub 2021 Apr 15.

School of Psychology, College of Engineering, Science, and the Environment, The University of Newcastle, Newcastle, NSW, Australia; School of Medicine and Public Health, College of Health and Medicine, The University of Newcastle, Newcastle, NSW, Australia; Hunter Medical Research Institute, Newcastle, NSW, Australia.

Predictive coding has played a transformative role in the study of psychosis, casting delusions and hallucinations as statistical inference in a system with abnormal precision. However, the negative symptoms of schizophrenia, such as affective blunting, avolition, and asociality, remain poorly understood. We propose a computational framework for emotional expression based on active inference-namely that affective behaviours such as smiling are driven by predictions about the social consequences of smiling. Read More

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Psychopathological Syndromes Across Affective and Psychotic Disorders Correlate With Gray Matter Volumes.

Schizophr Bull 2021 Apr 16. Epub 2021 Apr 16.

Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.

Introduction: More than a century of research on the neurobiological underpinnings of major psychiatric disorders (major depressive disorder [MDD], bipolar disorder [BD], schizophrenia [SZ], and schizoaffective disorder [SZA]) has been unable to identify diagnostic markers. An alternative approach is to study dimensional psychopathological syndromes that cut across categorical diagnoses. The aim of the current study was to identify gray matter volume (GMV) correlates of transdiagnostic symptom dimensions. Read More

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Magnitude and variability of structural brain abnormalities in neuropsychiatric disease: protocol for a network meta-analysis of MRI studies.

Evid Based Ment Health 2021 Apr 13. Epub 2021 Apr 13.

Department of Psychosis Studies, Institute of Psychiatry Psychology and Neuroscience, London, UK.

Introduction: Structural MRI is the most frequently used method to investigate brain volume alterations in neuropsychiatric disease. Previous meta-analyses have typically focused on a single diagnosis, thereby precluding transdiagnostic comparisons.

Methods And Analysis: We will include all structural MRI studies of adults that report brain volumes for participants from at least two of the following diagnostic groups: healthy controls, schizophrenia, schizoaffective disorder, delusional disorder, psychotic depression, clinical high risk for psychosis, schizotypal personality disorder, psychosis unspecified, bipolar disorder, autism spectrum disorder, major depressive disorder, attention deficit hyperactivity disorder, obsessive compulsive disorder, post-traumatic stress disorder, emotionally unstable personality disorder, 22q11 deletion syndrome, generalised anxiety disorder, social anxiety disorder, panic disorder, mixed anxiety and depression. Read More

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