8,907 results match your criteria Delusional Disorder

Relationships among subclinical psychotic symptoms in young adults over time.

Psychiatry Res 2022 May 10;314:114617. Epub 2022 May 10.

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Background: Subclinical psychotic symptoms are common in the general population and are often benign. However, those that become distressing or persistent may increase risk for the development of a psychotic disorder. Cognitive models have proposed that certain appraisals of hallucinatory experiences can lead to delusional beliefs, particularly if an individual is experiencing negative mood. Read More

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Psychiatric reaction of an intensive care unit survivor in the context of coronavirus disease 2019: a case report.

J Med Case Rep 2022 Jun 23;16(1):263. Epub 2022 Jun 23.

Department of Neurosciences, Service of Neurology, University Hospital of Geneva, 4, Rue Gabrielle Perret-Gentil, 1205, Geneva, Switzerland.

Background: The coronavirus disease 2019 pandemic has had a serious impact on global mental health, particularly in intensive care unit survivors. Given the lethal potential and unpredictability of coronavirus disease 2019, a high risk of posttraumatic stress disorder was identified in the beginning of the crisis. There are insufficient details in current literature and no official guidelines available for the treatment and follow-up of acute stress disorder and the prevention of posttraumatic stress disorder for intensive care unit survivors in the context of coronavirus disease 2019. Read More

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Distinguishing delusional beliefs from overvalued ideas in Anorexia Nervosa: An exploratory pilot study.

J Eat Disord 2022 Jun 23;10(1):85. Epub 2022 Jun 23.

School of Psychology, Faculty of Science, University of Sydney, Sydney, NSW, Australia.

Background: Characterised by the belief that more weight needs to be lost-despite emaciation, failing organs, medical instability and prospect of death-Anorexia Nervosa (AN) is a condition in which irrational, and highly-skewed, beliefs can be of delusional intensity. However, the nexus between delusion and rational awareness and how this is related to body image acceptance and perception has yet to be examined in AN. The current study aims to investigate the relationship between body dissatisfaction and beliefs of delusional intensity in an adult AN inpatient sample. Read More

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One-year mortality of emergency department patients with substance-induced psychosis.

PLoS One 2022 21;17(6):e0270307. Epub 2022 Jun 21.

Department of Emergency Medicine, University of British Columbia, Vancouver, Canada.

Objectives: Psychosis is a well established complication of non-prescription drug use. We sought to measure the 1-year mortality of emergency department patients with substance-induced psychosis (SIP).

Methods: This study was a multi-centre, retrospective electronic medical records review of patients presenting to the ED with substance-induced psychosis (SIP). Read More

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The network structure of paranoia dimensions and its mental health correlates in the general population: The core role of loneliness.

Schizophr Res 2022 Jun 16;246:65-73. Epub 2022 Jun 16.

University of Sheffield, Clinical Psychology Unit, Department of Psychology, United Kingdom.

Paranoid ideas are the most common abnormal beliefs in the schizophrenia spectrum, are also prevalent in non-clinical populations, and are highly correlated with other mental health problems such as anxiety, depression and low levels of well-being. Two previous studies with the same British population sample used confirmatory factor analysis and network analysis to show that the spectrum of paranoid beliefs is made up of four factors or dimensions (i.e. Read More

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A Case Report of Leukocytosis During Modified Electroconvulsive Therapy of Paranoid Personality Disorder.

Front Psychiatry 2022 26;13:899847. Epub 2022 May 26.

Department of General Practice, West China Hospital, Sichuan University, Chengdu, China.

Introduction: Modified electroconvulsive therapy (MECT) is a viable therapeutic option for patients with mood disorders and schizophrenia. We found that there is a relationship between MECT and leukocytosis. To the best of our knowledge, this is the first case of this problem. Read More

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Diagnostic and Therapeutic Implications of Organic Delusional Disorder due to Tuberculous Adrenalitis.

Case Rep Psychiatry 2022 1;2022:5056976. Epub 2022 Jun 1.

Department of Psychiatry, Mahatma Gandhi Medical College & Research Institute (MGMC&RI), Sri Balaji Vidyapeeth (Deemed to be University), Pondicherry, India.

Primary adrenal insufficiency rarely occurs due to infections, which consequently involves destruction or dysfunction of both adrenal cortices. Tuberculous adrenalitis is still a frequent cause of adrenal insufficiency in developing countries. We present the case of origin of multiple delusions along with recurrent spells of vomiting and giddiness in a patient with pulmonary tuberculosis (TB). Read More

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Differences between delusional disorder and schizophrenia: A mini narrative review.

World J Psychiatry 2022 May 19;12(5):683-692. Epub 2022 May 19.

Department of Psychiatry, University of Toronto, Toronto M5P 3L6, Ontario, Canada.

Psychotic syndromes are divided into affective and non-affective forms. Even among the non-affective forms, substantial differences exist. The aim of this relatively brief review is to synthesize what is known about the differences between two non-affective psychoses, schizophrenia and delusional disorder (DD), with respect to clinical, epidemiological, sociodemographic, and treatment response characteristics. Read More

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Serial killing in schizophrenia.

Clin Case Rep 2022 Jun 2;10(6):e05922. Epub 2022 Jun 2.

Faculty of Medicine of Tunis Tunis El Manar University Manouba Tunisia.

Serial criminality, although rare, has always aroused the interest of researchers in criminology, psychiatry, psychology, and sociology. We report the case of a patient, suffering from a chronic psychotic disorder, having committed several murders over a period of 9 years, underpinned by a delirium of misidentification of Frigoli syndrome. Read More

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Quality of Life in Patients with Chronic Psychotic Disorders: A Practical Model for Interventions in Romanian Mental Health Centers.

Medicina (Kaunas) 2022 Apr 28;58(5). Epub 2022 Apr 28.

Discipline of Psychiatry, Department of Clinical Sciences, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Str. G. Marinescu, 540139 Targu Mures, Romania.

: Current psychiatric care is increasingly focusing on patients' quality of life (QoL). Research is still trying to determine the main factors which influence QoL. The present study aims to assess the QoL of patients with chronic psychotic-spectrum disorders, as well as its relation to symptomatology, functionality, adaptive behavior, and perceived level of recovery. Read More

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[Detecting and Treating Comorbid Disorders in First-Episode Psychosis: A Lever for Recovery].

Sante Ment Que 2021 ;46(2):307-330

Faculté de médecine, Université Laval ; Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale (Institut universitaire en santé mentale de Québec) ; Centre de recherche CERVO, Québec.

Objectives Comorbidities that are less well known than substance use disorders may occur in individuals experiencing a first-episode psychosis (FEP). This article reviews the importance of these comorbidities through a synthesis of the literature, informed by the authors' clinical experience. Methods Five main groups of comorbidities are discussed: anxiety and obsessive-compulsive disorders, depression, borderline personality disorder, gambling disorder and attention deficit disorder. Read More

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Woman diagnosed with obsessive-compulsive disorder became delusional after childbirth: A case report.

World J Clin Cases 2022 Apr;10(10):3261-3267

Department of Psychiatry and Psychology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province,

Background: Obsessive-compulsive disorder (OCD) is a common mental disorder that varies greatly in manifestation and causes much distress to individuals. We describe a case in which a Chinese woman with OCD became delusional after childbirth, and discuss the possible phenomenological and psychological alterations.

Case Summary: A 27-year-old woman presented to the Psychiatry Department of our hospital with obsessions and compulsions. Read More

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[Hospital epidemiology of psychiatric disorders in Mali].

Pan Afr Med J 2022 23;41:160. Epub 2022 Feb 23.

Faculté de Médecine et d´Odontostomatologie de Bamako, Bamako, Mali.

Introduction: in Mali, there are no data on the prevalence of mental disorders. The purpose of this study was to describe the clinical and epidemiological features of patients hospitalised in the Department of Psychiatry.

Methods: we conducted a cross-sectional study in the Department of Psychiatry at the University Hospital of Point G between January 2014 and December 2018. Read More

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Between self-stigma and the will of recovery... Difficulties in accepting a psychiatric diagnosis - case study.

Psychiatr Pol 2022 Feb 27;56(1):183-193. Epub 2022 Feb 27.

Uniwersytet Medyczny w Lublinie, II Klinika Psychiatrii i Rehabilitacji Psychiatrycznej.

The consequence of social exclusion of the mentally ill patients is often a worsening of the course of the disease and prognosis. The psychiatric diagnosis is very important for the so-called labeling, which is one of the stages of the stigma process, and it also has a lot of social implications. The purpose of this work is to take look at the issue of psychiatric diagnosis, especially the diagnosis of paranoid schizophrenia and its consequences for the patient's social functioning. Read More

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February 2022

Lexical indicators of anxiety in schizophrenia.

Anxiety Stress Coping 2022 May 13:1-16. Epub 2022 May 13.

Faculty of Psychology and Cognitive Science, Adam Mickiewicz University, Poznań, Poland.

Background And Objectives: Anxiety is a dominant emotion in schizophrenia. It is most often diagnosed by questionnaire-based methods. In this study, it was decided to analyse the utterances of patients with schizophrenia for the occurrence of lexical indicators of anxiety, which are a good predictor of experienced anxiety and lie beyond the subject's control. Read More

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Shared Psychotic Disorder in Old Age: Syndrome of Folie à Deux.

Case Rep Psychiatry 2022 2;2022:8811140. Epub 2022 May 2.

Department of Geriatric Psychiatry, Geneva University Hospitals, Switzerland.

Background: Shared psychotic disorder is a relatively rare condition first described by Lasegue and Falret in 1877, who named the syndrome "folie à deux" (FAD). This disorder is characterized by the transference of delusional ideas from one individual to another.

Methods: We report the case of a mother and daughter who exhibited shared delusions of persecution after living in near-total isolation for 10 years. Read More

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A Clinical and Psychopathological Approach to Radicalization Among Adolescents.

Front Psychiatry 2022 25;13:788154. Epub 2022 Apr 25.

Service de Psychiatrie de l'Enfant et de l'Adolescent, Hôpital Pitié-Salpêtrière, APHP.SU, Paris, France.

Recent studies have shown higher rates of radicalization of adolescents than in the 2000s. Since 2015, radicalization prevention units have been implemented in child and adolescent psychiatry departments in France. We aimed to report on the psychopathology of adolescents who were followed up in a university department due to their "radical conduct. Read More

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Association of Variants in and with the Risk of Paranoid Schizophrenia Patients in Prof HB Saanin Psychiatric Hospital, West Sumatra, Indonesia.

Malays J Med Sci 2022 Apr 21;29(2):31-42. Epub 2022 Apr 21.

Master's Programme in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Background: Schizophrenia is a multifactorial disease in which genetic factors play a greater role than other factors. The genes of importance in schizophrenia patients are the genes that encode for neurotransmitters associated with low minor allele frequency (MAF) scores. This study was aimed to determine the association of genetic variations in , and with the risk of paranoid schizophrenia (PS) in patients admitted to Prof HB Saanin Psychiatric Hospital, West Sumatra, Indonesia. Read More

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Subjective experience and meaning of delusions in psychosis: a systematic review and qualitative evidence synthesis.

Lancet Psychiatry 2022 06 4;9(6):458-476. Epub 2022 May 4.

Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, UK; Early Intervention in Psychosis Service, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.

Background: Delusions are a common transdiagnostic feature of psychotic disorders, and their treatment remains suboptimal. Despite the pressing need to better understand the nature, meaning, and course of these symptoms, research into the lived experience of delusional phenomena in psychosis is scarce. Thus, we aimed to explore the lived experience and subjective apprehension of delusions in help-seeking individuals with psychosis, regardless of diagnosis and thematic content of the delusion. Read More

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Shared Psychotic Disorder Associated With Bipolar Disorder in the Primary Case in the Context of Opioid Misuse.

J Psychiatr Pract 2022 05 1;28(3):259-264. Epub 2022 May 1.

Bipolar disorder (BD) is a serious chronic mood disorder associated with high rates of co-occurring substance use disorders. Shared psychotic disorder (SPD) is a rare clinical phenomenon and has been reported in only a few cases of individuals diagnosed with BD. Furthermore, reports concerning SPD being induced by substance use or withdrawal are lacking. Read More

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Communication and Handoff Errors Within Treatment-Resistant Bipolar I Disorder.

Cureus 2022 Mar 31;14(3):e23703. Epub 2022 Mar 31.

Department of Behavioral Medicine and Psychiatry, Farhat Medical Clinic, Beckley, USA.

Bipolar I disorder includes periods of acute mania, e.g., symptoms of risk-taking behavior and impulsivity, which may result in interpersonal conflict with long-term implications. Read More

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DMS: Delusional Misidentification Syndrome or Dead Moneyman and Sex Offender? A Case Report of Reverse Capgras Syndrome.

Case Rep Psychiatry 2022 20;2022:9703482. Epub 2022 Apr 20.

Lehigh Valley Health Network, Bethlehem, PA, USA.

Delusional misidentification syndromes (DMSs) are delusional phenomena where individuals believe that one has been altered or replaced. Here, we present the case of Ms. JS, who exemplifies one such DMS, Reverse Capgras Syndrome, which refers to the delusion that one has been replaced by an imposter. Read More

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Activity of selected metalloproteinases in neurodegenerative diseases of the central nervous system as exemplified by dementia and schizophrenia.

Psychiatr Pol 2021 Dec 31;55(6):1221-1233. Epub 2021 Dec 31.

Uniwersytet Medyczny w Lublinie, Katedra i Zakład Chemii Medycznej.

Objectives: The aim of the study was to determine and analyze the correlation between the concentrations of selected metalloproteinases and their inhibitors (TIMP-1 and TIMP-2) in patients with dementia and schizophrenia.

Methods: The concentration of two collagenases and metalloendopeptidase was determined in the study. The study included 29 patients with lateonset dementia, 25 patients with paranoid schizophrenia and 25 healthy controls who were age-matched with the study groups. Read More

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December 2021

Belief Updating and Paranoia in Individuals with Schizophrenia.

Biol Psychiatry Cogn Neurosci Neuroimaging 2022 Apr 14. Epub 2022 Apr 14.

Department of Psychiatry, Connecticut Mental Health Center, Yale University, New Haven, United States.

Background: Persecutory delusions are among the most common delusions in schizophrenia and represent the extreme end of the paranoia continuum. Paranoia is accompanied by significant worry and distress. Identifying cognitive mechanisms underlying paranoia is critical for advancing treatment. Read More

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Association of VEGF-A and KDR polymorphisms with the development of schizophrenia.

Hum Immunol 2022 Jun 12;83(6):528-537. Epub 2022 Apr 12.

Laboratory of Genetics, Biodiversity and Bioresource Valorization (LR11ES41), Higher Institute of Biotechnology of Monastir, University of Monastir, Tunisia.

Aim: Several approaches indicate different blood flow disturbances in schizophrenia. VEGF-A is widely recognized as one of the key molecules involved in the angiogenesis process through mainly its receptor KDR. The current work was designed to investigate the potential association between three polymorphisms (rs699947; rs833061 and rs3025039) in VEGF-A gene and two SNPs (rs2305948 and rs1870377) within KDR gene and predisposition to schizophrenia among the Tunisian cohort. Read More

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Thinking biases and their role in persecutory delusions: A systematic review.

Early Interv Psychiatry 2022 Apr 9. Epub 2022 Apr 9.

King's College London, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), London, England.

Aim: Thinking biases are posited to be involved in the genesis and maintenance of delusions. Persecutory delusions are one of the most commonly occurring delusional subtypes and cause substantial distress and disability to the individuals experiencing them. Their clinical relevance confers a rationale for investigating them. Read More

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A firearm double homicide committed by a paranoid neigh- bor: a psychopathological study.

Clin Ter 2022 Apr;173(2):99-103

S.C. Forensic Medicine U, A.O.U. City of Health and Science of Turin, Turin, Italy.

Abstract: Serious mental illness is associated with a higher risk of violent interpersonal behavior. Characteristic traits denoting a psychopatho-logical picture such as schizophrenia, depression, a borderline, or narcissistic, antisocial, or paranoid personality disorder, are frequently observed in the personality of those who have committed one or more murders. For example, mass murderers are affected by a delusional syndrome with a persecution fixation, that develops in a subject with a paranoid, anacastic personality disorder. Read More

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Psychiatric Morbidity in Irritable Bowel Syndrome.

Mymensingh Med J 2022 Apr;31(2):458-465

Dr Md Enamul Hoque Khan, Associate Professor, Department of Psychiatry, Sheikh Hasina Medical College, Tangail, Bangladesh; E-mail:

Psychiatric morbidity is frequent among outpatients with Irritable Bowel Syndrome (IBS) attending gastroenterology clinics. The lifetime prevalence of major depressive and anxiety disorders in IBS patients are up to 76% and 54% respectively. The point prevalence of Major depressive disorder and Anxiety disorders in IBS patients are ranged 9. Read More

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