8,353 results match your criteria Delusional Disorder


[The « syndrome de glissement »].

Authors:
Thomas Desmidt

Rev Prat 2019 Jan;69(1):80-82

CHRU de Tours, Tours, France ; Inserm U1253 (iBrain) Imagerie et Cerveau, Tours, France.

The "syndrome de glissement" The "syndrome de glissement » is a controversial notion that is still used by some French geriatricians, although it does not belong to any international disease classification and has very few evidence-based data. Some authors found clinical relevance to this notion, whereas others believe its use is potentially associated with certain risks. The clinical practice and the few available evidence related to syndrome de glissement" tend to suggest that this syndrome usually belong to other disorders including apathy, depression and delusional disorder. Read More

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January 2019
2 Reads

Reduplicative paramnesia for places: A comprehensive review of the literature and a new case report.

Clin Neurol Neurosurg 2019 Apr 2;181:7-20. Epub 2019 Apr 2.

Center for Mind/Brain Sciences, University of Trento, 38068, Rovereto, Italy; Centro Interdisciplinare Linceo 'Beniamino Segre', Accademia dei Lincei, Rome, Italy. Electronic address:

Reduplicative paramnesia for places (i.e., the delusional belief that a place has been duplicated or exists in two different locations) is a rare disorder observed in neurological patients. Read More

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http://dx.doi.org/10.1016/j.clineuro.2019.03.022DOI Listing
April 2019
1 Read

'Something wasn't quite right': a novel phenomenological analysis of internet discussion posts detailing initial awareness of psychosis.

Clin Schizophr Relat Psychoses 2019 Apr 2. Epub 2019 Apr 2.

School of Psychology, Ulster University, Northern Ireland.

Introduction: A significant number of psychosis studies have focussed on and have attempted to model and frame the earliest psychosis experiences. Using a wide array of methodologies and targeting a variety of 'at risk' groups, researchers have offered much to inform our treatment responses, and understanding of psychosis onset and development.

Objectives: Due to the nature of scientific investigation however and investigator led exploration, those who experience psychosis are rarely afforded ultimate free rein to dictate and direct the exchange of information or to impose their unique narrative on that which is being explored. Read More

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http://dx.doi.org/10.3371/CSRP.SPJM.032819DOI Listing
April 2019
4 Reads

Can typical and atypical antipsychotics show differential effectiveness in treating paranoia and hallucinations in schizophrenia?

BMJ Case Rep 2019 Mar 31;12(3). Epub 2019 Mar 31.

Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.

A dopamine excess is thought to be involved in positive psychotic symptoms in schizophrenia. All current antipsychotics show a degree of dopamine receptor antagonism. Little is known about the differential effectiveness of different antipsychotics in treating specific sets of symptoms. Read More

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http://dx.doi.org/10.1136/bcr-2018-228573DOI Listing
March 2019
3 Reads

Antisocial Personality Traits as a Risk Factor of Violence between Individuals with Mental Disorders.

Authors:
Izabela Filov

Open Access Maced J Med Sci 2019 Feb 25;7(4):657-662. Epub 2019 Feb 25.

Higher Medical School, University "St Kliment Ohridski", Bitola, Republic of Macedonia.

Background: Mental disorder can increase the likelihood of taking violent acts of some individuals, but only a small percentage of violence in societies could be attributed to patients with mental health problems. For the past several years numerous studies related to forensic psychiatry has confirmed a close causal relationship between violent offenders and psychiatric comorbidity. Several studies have provided strong evidence that antisocial personality disorders (APD) represent a significant clinical risk for violence. Read More

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http://dx.doi.org/10.3889/oamjms.2019.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420958PMC
February 2019
1 Read

Psychopathological Influence of Middle Fossa Arachnoid Cysts in Young Men: Analysis of Korean Conscription Data.

World Neurosurg 2019 Feb 25;122:e530-e539. Epub 2018 Oct 25.

Department of Neurosurgery, College of Medicine, Chung-Ang University, Seoul, Korea.

Background: A few reported studies have documented psychotic syndromes secondary to a middle fossa arachnoid cyst (AC). However, the association between middle fossa ACs and psychopathological symptoms remains to be determined. The present study investigated the psychopathological effects of middle fossa ACs in young men. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.095DOI Listing
February 2019
3 Reads

[Persistent delusional disorder].

Rev Prat 2018 Dec;68(10):e411-e414

Service de psychiatrie et d'addictologie, hôpital universitaire Paul-Brousse, AP-HP, université Paris Sud-11, France.

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December 2018
1 Read

65 A Retrospective Study of Aripiprazole Long-acting Once-Monthly Introduction Patterns in Galicia.

CNS Spectr 2019 Feb;24(1):210

2Psychiatrist,Department of adult psychiatry,Ferrol Hospital,Spain Águeda Fernández Quintana,MD: Psychiatrist,Department of adult psychiatry,Västmanl and Hospital,Sweden.

Background: Antipsychotic drug treatment is a key component of multiple psychiatric treatment algorithms. Second-generation long-acting injectable antipsychotics (LAIs) have been shown to improve adherence in numerous clinical trials. Patients who can benefit from LAIs therapy can be treated with aripiprazole long acting once-monthly (AOM). Read More

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http://dx.doi.org/10.1017/S1092852919000518DOI Listing
February 2019
5 Reads

57 Pareidolia as a Manifestation of Folie á Deux.

CNS Spectr 2019 Feb;24(1):205

2Smell and Taste Treatment and Research,Chicago,IL,USA.

IntroductionThe spreading of pareidolia, the visualization of one image inside another image, from one member of a couple to another one is seen in a subtype of folie á deux called folie imposée.Case studyA 27 year old right handed male started having delusions two years prior to presentation. He experienced marked hallucinations in which he saw faces imbedded in clothing and demon-like faces that would appear in curtain shades. Read More

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http://dx.doi.org/10.1017/S1092852919000440DOI Listing
February 2019
5 Reads

Resting-State Functional Connectivity and Psychotic-like Experiences in Childhood: Results From the Adolescent Brain Cognitive Development Study.

Biol Psychiatry 2019 Jan 26. Epub 2019 Jan 26.

Department of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri; Department of Radiology, Washington University School of Medicine in St Louis, St. Louis, Missouri; Department of Psychology, Washington University in St. Louis, St. Louis, Missouri.

Background: Psychotic-like experiences (PLEs) during childhood are associated with greater risk of developing a psychotic disorder (and other mental disorders), highlighting the importance of identifying neural correlates of childhood PLEs. Three major cortical networks-the cingulo-opercular network (CON), default mode network (DMN), and frontoparietal network-are consistently implicated in psychosis and PLEs in adults. However, it is unclear whether variation in functional connectivity is associated with PLEs in school-aged children. Read More

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http://dx.doi.org/10.1016/j.biopsych.2019.01.013DOI Listing
January 2019
1 Read

Commentary: Aripiprazole: The Second Wave of the Second-generation Antipsychotics.

Authors:
David A Kahn

J Psychiatr Pract 2019 Mar;25(2):146-147

KAHN: Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY.

Three cases are presented describing unique clinical responses to aripiprazole in comparison with other second-generation antipsychotics taken by each patient. One case involved an adverse reaction of problem gambling behavior, the second an enhanced antipsychotic response in delusional disorder, and the third a reversal of weight gain that occurred while the patient continued taking olanzapine. Aripiprazole was the first of a subgroup of atypical antipsychotics that are mixed agonists and antagonists of dopamine, likely contributing to unusual responses in some patients. Read More

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http://dx.doi.org/10.1097/PRA.0000000000000373DOI Listing

Aripiprazole and Delusional Disorder.

J Psychiatr Pract 2019 Mar;25(2):132-134

IANNUZZI, PATEL, and STEWART: Department of Psychiatry, James A Haley VA Hospital, University of South Florida College of Medicine, Tampa, FL.

Delusional disorder is a relatively rare psychotic illness characterized by delusions with contents that are theoretically possible but highly unlikely, and an absence of the disorganized thought and negative symptoms characteristic of schizophrenia. The illness is rarely studied systematically and most guidance with regard to the treatment derives from case reports and small case series. Antipsychotic medications are the mainstay of treatment, but it is not clear whether any particular agent is more effective than others. Read More

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http://dx.doi.org/10.1097/PRA.0000000000000368DOI Listing
March 2019
1 Read

Borderline Personality Disorder: Clinical Guidelines for Treatment.

Authors:
Michael H Stone

Psychodyn Psychiatry 2019 ;47(1):5-26

Professor of Clinical Psychiatry, Columbia College of Physicians & Surgeons.

Borderline personality disorder (BPD) is fundamentally a syndrome composed of symptoms (primarily of emotional dysregulation) and a number of true personality traits (such as inordinate anger, impulsivity, and a tendency to stress-related paranoid ideation). Whereas schizotypal personality disorder, with its cognitive peculiarities (ideas of reference, odd beliefs, eccentric speech), is closely linked as a genetic condition-"borderline" to the major condition schizophrenia-BPD is less closely linked to bipolar disorder. Some cases of BPD are linked genetically to and are in the "border" of bipolar disorder. Read More

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http://dx.doi.org/10.1521/pdps.2019.47.1.5DOI Listing
April 2019
2 Reads

Paranoid schizophrenia and methamphetamine-induced paranoia are both characterized by a similar LINE-1 partial methylation profile, which is more pronounced in paranoid schizophrenia.

Schizophr Res 2019 Feb 27. Epub 2019 Feb 27.

Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; IMPACT Strategic Research Center, Barwon Health, Geelong, Australia; Department of Psychiatry, Medical University of Plovdiv, Plovdiv, Bulgaria. Electronic address:

Background: There is evidence that schizophrenia is a neuro-immune disorder. Genes linked to intragenic LINE-1 methylation show a strong association with immune-associated disorders including psychosis. The aim of this study was to examine LINE-1 methylation patterns in paranoid schizophrenia and methamphetamine-induced paranoia, a model for schizophrenia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09209964193007
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http://dx.doi.org/10.1016/j.schres.2019.02.015DOI Listing
February 2019
7 Reads

Positive and general psychopathology associated with specific gray matter reductions in inferior temporal regions in patients with schizophrenia.

Schizophr Res 2019 Feb 25. Epub 2019 Feb 25.

Department of Psychology, Georgia State University, Atlanta, GA, USA.

Schizophrenia is a complex disorder that affects perception, cognition, and emotion causing symptoms such as delusions, hallucinations, and suspiciousness. Schizophrenia is also associated with structural cortical abnormalities including lower gray matter (GM) concentration, GM volume, and cortical thickness relative to healthy control individuals. However, the association between GM measures and symptom dimensions in schizophrenia is still not well understood. Read More

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http://dx.doi.org/10.1016/j.schres.2019.02.010DOI Listing
February 2019
1 Read

Olanzapine-Induced Fever.

Prim Care Companion CNS Disord 2019 02 28;21(1). Epub 2019 Feb 28.

Serviço de Psiquiatria, Hospital Prof Doutor Fernando da Fonseca, Amadora, Portugal.

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http://dx.doi.org/10.4088/PCC.18l02332DOI Listing
February 2019
2 Reads

Twenty years of misdiagnosis of schizophrenia in a patient with Dandy-Walker variant syndrome.

Gen Psychiatr 2019 29;32(1):e100031. Epub 2019 Jan 29.

Hospital Júlio de Matos, Centro Hospitalar Psiquiátrico de Lisboa; Clínica Universitária de Psiquiatria e Psicologia Médica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Various case reports of patients with Dandy-Walker variant syndrome mimicking schizophrenia have been published in the last 20 years, suggesting that this neurodevelopment disorder should be part of the differential diagnosis for every patient with a first episode of psychosis. In this report, it is presented that a patient who was diagnosed and treated as a paranoid schizophrenic for 20 years and had four bone fractures secondary to ataxic gait impairment, before performing a neuroimaging examination that revealed Dandy-Walker variant syndrome. Read More

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http://dx.doi.org/10.1136/gpsych-2018-100031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362872PMC
January 2019
3 Reads

Psychotic-Like Experiences in Offspring of Parents With Bipolar Disorder and Community Controls: A Longitudinal Study.

J Am Acad Child Adolesc Psychiatry 2018 Nov 3. Epub 2018 Nov 3.

University of Pittsburgh, PA.

Objective: To compare the prevalence and risk factors associated with psychotic-like experiences (PLE) in offspring of parents with bipolar disorder (BP) and offspring of community control parents.

Method: Delusional and hallucinatory subclinical psychotic experiences were evaluated at intake and longitudinally in a cohort study of 390 offspring of BP parents and 247 offspring of control parents; all offspring were between 6 and 18 years of age. The sample was followed up every 2. Read More

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http://dx.doi.org/10.1016/j.jaac.2018.09.440DOI Listing
November 2018
1 Read

Postinjection Delirium/Sedation Syndrome After 31st Long-Acting Olanzapine Depot Injection.

Clin Neuropharmacol 2019 Mar/Apr;42(2):64-65

Department of Psychiatry, Central Institute of Psychiatry, Ranchi, India.

Objective: Long-acting depot preparations of antipsychotics are the mainstay of treatment for patients with schizophrenia who show nonadherence to their medications. Olanzapine pamoate is one of the recently approved long-acting depot psychotropic preparations that have shown its efficacy both in clinical trials and in clinical uses against the illness. However, emerging literature indicates toward a cluster of adverse effects known as postinjection delirium/sedation syndrome (PDSS). Read More

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http://dx.doi.org/10.1097/WNF.0000000000000329DOI Listing
February 2019
9 Reads
1.836 Impact Factor

Leukocytoclastic vasculitis secondary to clozapine.

Indian J Psychiatry 2019 Jan-Feb;61(1):94-96

Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India.

Leukocytoclastic vasculitis (LCV) may be secondary to drugs, underlying infection, collagen vascular disorders, or malignancy. Drug-induced vasculitis contributes to 10% of vasculitic skin lesions cases usually developing within 7-21 days of treatment initiation. The present case highlights a report of LCV in a 59-year-old male with a history of paranoid schizophrenia on clozapine therapy. Read More

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http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_384_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341920PMC
February 2019
2 Reads

Psychoeducational therapy with families of paranoid schizophrenia patients.

Enferm Clin 2019 Feb 8. Epub 2019 Feb 8.

Department of Mental Health Nursing, Poltekkes Kemenkes Semarang, Prodi Keperawatan Magelang, Kota Magelang, Indonesia. Electronic address:

Aim: The study aimed to measure the effectiveness of psychoeducational therapy on the burden of families of paranoid schizophrenia patients.

Methods: An experimental research design was used in this study with an equivalent control group using 84 random allocation samples at a mental hospital in Semarang. The study instrument was the Indonesian version of the care burden scale (CBS). Read More

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http://dx.doi.org/10.1016/j.enfcli.2018.12.006DOI Listing
February 2019
2 Reads

Schizotypal traits, neurocognition, and paternal age in unaffected first degree relatives of patients with familial or sporadic schizophrenia.

Psychiatry Res 2019 Jan 2;273:422-429. Epub 2019 Jan 2.

Department of Psychology, Faculty of Social Sciences, University of Crete, Rethymno 74100, Crete, Greece.

Studies comparing cognitive processes between familial and sporadic schizophrenia have yielded inconsistent findings. In this study we examined differences in neurocognition and schizotypal traits in unaffected relatives of schizophrenia-spectrum patients with either the familial (multiplex) or the sporadic (simplex) subtype of the disorder, taking paternal age at birth into consideration. Simplex (n = 65; SR), multiplex (n = 35; MR) relatives and controls (n = 114) were compared on several cognitive functions and schizotypal traits; between-group differences were evaluated with and without including paternal age in the analyses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183151
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http://dx.doi.org/10.1016/j.psychres.2018.12.142DOI Listing
January 2019
10 Reads

A case report of the successful administration of clozapine in the face of myocardial infarction, pulmonary embolism and hyperlipidaemia resulting in the termination of long-term seclusion.

Authors:
Alex Till Ed Silva

BMC Psychiatry 2019 Jan 23;19(1):37. Epub 2019 Jan 23.

Ashworth Hospital, Mersey Care NHS Trust, Parkbourn, Maghull, Liverpool, Merseyside, L31 1HW, UK.

Background: Cardiometabolic health significantly impacts on the mortality of people with severe mental illness. Clozapine has the greatest efficacy for Treatment Resistant Schizophrenia (TRS) but the greatest negative impact on cardiometabolic health. Balancing the risks and benefits of treatment, dignity, autonomy, liberty, mental and physical health can be challenging, particularly when imposing interventions with potentially life threatening adverse events, such as clozapine. Read More

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http://dx.doi.org/10.1186/s12888-018-2001-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343332PMC
January 2019
5 Reads

Compulsory Psychiatric Admissions in an Italian Urban Setting: Are They Actually Compliant to the Need for Treatment Criteria or Arranged for Dangerous Not Clinical Condition?

Front Psychiatry 2018 8;9:740. Epub 2019 Jan 8.

Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.

Italy was one of the first European countries adopting the need for treatment criteria for compulsory admission (CA). The aim of the present study was to confirm whether CA in an urban setting in Italy was compliant with the requested clinical criteria. In this retrospective observational study, we retrieved all collected information regarding CA in Turin (Italy) from January 2006 to December 2013. Read More

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http://dx.doi.org/10.3389/fpsyt.2018.00740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331583PMC
January 2019
4 Reads

Gender dysphoria symptoms in schizophrenia.

Psychiatr Pol 2018 Dec 29;52(6):1053-1062. Epub 2018 Dec 29.

Instytut Psychiatrii i Neurologii w Warszawie, III Klinika Psychiatryczna.

Gender dysphoria in individuals with schizophrenia may result from the delusionally changed gender identity or appear regardless of psychotic process. Distinguishing between these situations is not only a diagnostic challenge, but also affects the therapeutic decisionmaking. The review of the literature shows that different delusional beliefs regarding belonging to another gender, anatomy or changes within the genitals affect about one-fourth of patients with schizophrenia. Read More

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http://dx.doi.org/10.12740/PP/80013DOI Listing
December 2018
3 Reads

Long non-coding RNA MIAT competitively binds miR-150-5p to regulate ZEB1 expression in osteosarcoma.

Oncol Lett 2019 Jan 7;17(1):1229-1236. Epub 2018 Nov 7.

Department of Orthopaedics, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150006, P.R. China.

Long non-coding RNAs (LncRNAs), are significant in a number of biological stages and illnesses. The myocardial infarction associated transcript (MIAT) serves a function in numerous types of illness and physiological and pathological processes, including paranoid schizophrenia, diabetic retinopathy, myocardial infarction and neuroendocrine prostate cancer. However, the function of the lncRNA MIAT in the development of osteosarcoma is unknown. Read More

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http://www.spandidos-publications.com/10.3892/ol.2018.9671
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http://dx.doi.org/10.3892/ol.2018.9671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312950PMC
January 2019
9 Reads
0.987 Impact Factor

Guanfacine Augmentation of a Combined Intervention of Computerized Cognitive Remediation Therapy and Social Skills Training for Schizotypal Personality Disorder.

Am J Psychiatry 2019 Apr 18;176(4):307-314. Epub 2019 Jan 18.

Department of Psychiatry, Mt. Sinai School of Medicine, New York (McClure, Perez-Rodriguez, Rosell, Koenigsberg, Hazlett, Siever, New); Department of Psychology, Fairfield University, Fairfield, Conn. (McClure); War Related Illness and Injury Study Center, VA New Jersey Health Care System, East Orange (Graff); Department of Veterans Affairs, VISN2 Mental Illness Research, Education, and Clinical Center, Bronx, N.Y. (Triebwasser, Koenigsberg, Hazlett, Siever); Department of Psychiatry, University of Miami Miller School of Medicine, Miami (Harvey).

Objective:: Impaired cognition is a hallmark of schizophrenia spectrum disorders, including schizotypal personality disorder, and it is the best predictor of functional outcome. Cognitive remediation therapy has demonstrated efficacy for improving cognition, augmenting other rehabilitation efforts in schizophrenia, and effecting gains in real-world functioning. Pharmacological augmentation of cognitive remediation has been attempted, but the effects of augmentation on combined therapies, such as cognitive remediation and social skills training, have not been studied. Read More

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.18
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http://dx.doi.org/10.1176/appi.ajp.2018.18030349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443471PMC
April 2019
11 Reads

Modelling and forecasting Positive and Negative Syndrome Scale scores to achieve remission using time series analysis.

Int J Methods Psychiatr Res 2019 Mar 16;28(1):e1763. Epub 2019 Jan 16.

Department of Psychiatry & Drug Deaddiction Centre, Lady Hardinge Medical College & Smt. S.K. Hospital, New Delhi, India.

Objectives: Schizophrenia is a chronic mental condition. The objective of this study is to apply time series modelling to Positive and Negative Syndrome Scale scores of outpatients with schizophrenia, observed at regular intervals of time, and hence forecast the number of visits required to reach remission.

Methods: A retrospective data of outpatients diagnosed with chronic paranoid-type schizophrenia were extracted from the records of outpatient department of a tertiary hospital in New Delhi, India. Read More

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http://doi.wiley.com/10.1002/mpr.1763
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http://dx.doi.org/10.1002/mpr.1763DOI Listing
March 2019
9 Reads

Therapeutic Particularities with Depot Medications in Schizophrenia.

Curr Health Sci J 2018 Jul-Sep;44(3):322-325. Epub 2018 Jul 15.

Department of Psychiatry, Clinical Hospital of Neuropsychiatry Craiova.

Schizophrenia is a neurodegenerative disease with personality degradation, changes in behavior, cognition, affective disorder and reduced socio-professional insertion. Early diagnosis is necessary and maintenance is ensured by antipsychotic treatment and for non-compliant patients there is an alternative to depot medication that greatly improves therapeutic adherence. The study presents the case of a 43-year-old patient diagnosed with paranoid schizophrenia using the Diagnostic and Statistical Manual of Mental Disorders V-TR criteria that showed a favorable evolution under depot treatment. Read More

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http://dx.doi.org/10.12865/CHSJ.44.03.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311213PMC
July 2018
3 Reads

The contribution of optimism and hallucinations to grandiose delusions in individuals with schizophrenia.

Schizophr Res 2019 Jan 10. Epub 2019 Jan 10.

University Department of Adult Psychiatry, Hospital La Colombière, CHU Montpellier, France; Univ. Paul Valéry Montpellier 3, Univ. Montpellier, EPSYLON EA 4556, F34000, Montpellier, France.

Grandiose delusions (GDs) are defined as false beliefs about having an inflated worth, power, or a special identity which are firmly sustained despite undeniable evidence to the contrary. Although it is the second most commonly encountered delusional beliefs, GDs have received little attention. Thus, in this study, we explored the role of future expectations and sensitivity to reward in GDs in schizophrenia (SZ) disorder. Read More

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http://dx.doi.org/10.1016/j.schres.2018.12.037DOI Listing
January 2019
4 Reads

[Child Protection in Families with Parental Mental Illness].

Prax Kinderpsychol Kinderpsychiatr 2019 Jan;68(1):6-26

Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters der Charité Deutschland Klinik für Psychiatrie, Psychosomatik und Psychotherapie.

Child Protection in Families with Parental Mental Illness Children and adolescents from families with parental mental illness face an increased risk to experience abuse, neglect and maltreatment. The effects of imminent, intermittent or chronic distress on the development of the child and to differentiate these from neglect or maltreatment are not easily assignable in such families. Questionnaires and diagnostic instruments can be supportive tools for professionals in hospitals and private practices to identify and differentiate between burdens of children and families and potential endangerment. Read More

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https://www.vr-elibrary.de/doi/10.13109/prkk.2019.68.1.6
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http://dx.doi.org/10.13109/prkk.2019.68.1.6DOI Listing
January 2019
18 Reads

Haplotypes of TNF/ Genes Associated with Sex-Specific Paranoid Schizophrenic Risk in Tunisian Population.

Dis Markers 2018 5;2018:3502564. Epub 2018 Dec 5.

Laboratory of Genetics, Biodiversity and Bioresource Valorization, Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.

Several medical research findings have announced a strong association between the biology of cytokines and various brain activities. Since growing evidences suggest the crucial and complex role of the tumor necrosis factor in the CNS, we have hypothesized that functional genetic variants of the LTA and TNFA genes (LTA +252A/G (rs909253) and TNFA -857C/T (rs1799724) and TNFA -238G/A (rs361525)) may be involved in the predisposition to schizophrenia. This research is based on a case-control study. Read More

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http://dx.doi.org/10.1155/2018/3502564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304811PMC
December 2018
2 Reads

The expression of toll-like receptors in peripheral blood mononuclear cells is altered in schizophrenia.

Psychiatry Res 2019 02 28;272:540-550. Epub 2018 Dec 28.

Department of Experimental Immunology, Medical University of Lodz, Pomorska 251, 92-213, Lodz, Poland. Electronic address:

Increasing evidence suggests that in addition to neurochemical abnormalities, various immunological alterations are related to the pathogenesis of schizophrenia. Toll-like receptors (TLRs) actively mediate immune/inflammatory processes and play a pivotal role in damage/danger recognizing. Therefore, the aim of this study was to compare the expression of TLRs in peripheral blood mononuclear cells (PBMCs) in schizophrenic patients with those of healthy subjects. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.138DOI Listing
February 2019
2 Reads

[A brief historical approach about the concept of paranoia].

Vertex 2018 Jan;29(137):72-77

Departamento de Psiquiatría, Harvard Medical School, Boston. Centros Lucio Bini para los Trastornos del Ánimo, Cagliari y Roma, Italia. International Consortium for Bipolar & Psychotic Disorders Research, Boston, EE.UU.

From the ancient Greeks (V to III centuries BC), through Hippocrates to the Roman physician Aulo Cornelius Celso (I century), the term paranoia has been used as a manifestation of mental illness. After many centuries, Robert Burton in 1621 introduces the concept with a more modern meaning. Only with Heinroth (1818) the syndrome enters into the psychiatric nosology as a disorder of thought with unaltered perceptions. Read More

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January 2018
2 Reads

Choline Compounds of the Frontal Lobe and Temporal Glutamatergic System in Bipolar and Schizophrenia Proton Magnetic Resonance Spectroscopy Study.

Dis Markers 2018 25;2018:3654894. Epub 2018 Nov 25.

Department of Psychiatry, Medical University of Białystok, Plac Brodowicza 1, 16-070 Choroszcz, Poland.

Purpose: Modern neuroimaging techniques allow investigating brain structures and substances involved in the pathophysiology of mental disorders, trying to find new markers of these disorders. To better understanding of the pathophysiology and differential diagnosis of schizophrenia and bipolar disorder, this study was conducted to assess the neurochemical alterations in the frontal and temporal lobes in hospitalized patients with schizophrenia and bipolar disorder.

Methods: Twenty-one subjects with schizophrenia (paranoid and differentiated types), 16 subjects with bipolar I disorder (manic, depressive, and mixed episode), and 20 healthy subjects were studied. Read More

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http://dx.doi.org/10.1155/2018/3654894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286772PMC
April 2019
2 Reads

[The activity of erythrocyte and platelet glutathione reductase and glutathione-S-transferase in paranoid schizophrenia].

Zh Nevrol Psikhiatr Im S S Korsakova 2018;118(11):77-81

Mental Health Research Centre, Moscow, Russia.

Aim: A comparative evaluation of glutathione reductase (GR) and glutathione-S-transferase (GST) activities in erythrocytes and platelets of patients with schizophrenia.

Material And Methods: Fifty patients, 47 men and 3 women, aged 25-56 years (medium 34) with acute paranoid schizophrenia (F20.0 ICD-10) with hallucinatory-paranoid or paranoid syndrome were studied. Read More

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http://dx.doi.org/10.17116/jnevro201811811177DOI Listing
January 2018
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Exploring the relationship between fantasy proneness and delusional beliefs in psychosis and non-clinical individuals.

Psychiatry Res 2019 02 17;272:80-85. Epub 2018 Dec 17.

Centre for Mental Health, Swinburne University of Technology, Hawthorn, VIC, Australia; St Vincent's Mental Health Service, St Vincent's Hospital, Melbourne, VIC, Australia.

Delusions are a core feature of psychopathology while fantasy proneness (FP) is a trait that describes a predisposition towards fantastical thinking, vivid mental imagery and an overactive imagination. The relationship between FP and delusional experiences has not yet been examined in the literature. The current study hypothesised that FP would be significantly associated with and predict delusion severity as well as the associated delusional distress, preoccupation and conviction. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.081DOI Listing
February 2019
2 Reads

Mental and behavioral disorders in workers: a study on work leave.

Rev Esc Enferm USP 2018 Dec 13;52:e03396. Epub 2018 Dec 13.

Universidade Federal do Piauí, Departamento de Enfermagem, Teresina, PI, Brasil.

Objective: To analyze workers' cases of work leave caused by mental and behavioral disorders.

Method: A cross-sectional census study conducted between June and July 2017 in which data were used from the National Social Security Institute database, with all workers' records. Data were analyzed by using descriptive statistics and inferential tests. Read More

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http://dx.doi.org/10.1590/S1980-220X2017036403396DOI Listing
December 2018
3 Reads

Maternal Infanticide and Filicide in a Psychiatric Custodial Institution in Hong Kong.

Authors:
D Tang B Siu

East Asian Arch Psychiatry 2018 Dec;28(4):139-143

Department of Forensic Psychiatry, Castle Peak Hospital, Hong Kong.

Objective: The aim of this study was to review the history, legislation, and psychiatric perspective of filicide, to compare the characteristics of mothers who committed neonaticide versus infanticide, and to discuss the infanticide law in Hong Kong.

Methods: Data of mothers remanded to the Siu Lam Psychiatric Centre from 2008 to 2016 for filicide were reviewed, as were data of filicide from the Child Fatality Review Reports published by the Social Welfare Department.

Results: From 2008 to 2016, eight mothers were remanded to Siu Lam Psychiatric Centre for filicide. Read More

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December 2018
2 Reads

Improvement in renal prognosis with prompt hemodialysis in hyperosmolar hyperglycemic state-related rhabdomyolysis: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13647

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan City, Taiwan.

Rationale: Acute kidney injury is common and correctable in patients with a hyperosmolar hyperglycemic state (HHS). Nevertheless, hyperglycemic crisis may also contribute to the development of rhabdomyolysis, which can worsen renal function and lead to high mortality in such patients.

Patient Concerns: Herein, we report a case of hyperosmolar hyperglycemic state-related rhabdomyolysis and acute renal failure with an excellent outcome. Read More

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http://dx.doi.org/10.1097/MD.0000000000013647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319979PMC
December 2018
3 Reads

Disturbances of intentionality in schizophrenia and in depression.

Actas Esp Psiquiatr 2018 Nov 1;46(6):234-41. Epub 2018 Nov 1.

Ph. D., Director of the Department of Psychiatry East of the Faculty of Medicine of the University of Chile.

After defining that fundamental element of psychic life which is intentionality, based on original descriptions by Franz Brentano and Edmund Husserl, the authors try to show the way in which this phenomenon is respectively altered in schizophrenia and in depression. For understanding what occurs with respect to this in schizophrenia it is first necessary to focus on what Husserl calls “the consciousness of the interior or immanent time”. The current of consciousness is not a mere succession of “nows”, but of a process of dynamic self-organization, which begins to be developed as, for example, a lecture or a melody is heard. Read More

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November 2018
4 Reads

Capgras syndrome in substance-induced psychosis.

Ment Illn 2018 Nov 6;10(2):7807. Epub 2018 Nov 6.

University of California Irvine, Orange, CA, USA.

Capgras Syndrome is a subcategory of delusional disorder. People affected by this syndrome believe that a close associate such as a friend or family member has been replaced by an identical imposter. This case report describes a 23-year-old woman with no prior psychiatric history, whom developed Capgras syndrome, via , in the setting of poly-substance use. Read More

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http://dx.doi.org/10.4081/mi.2018.7807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240921PMC
November 2018
1 Read

Latent Psychotic Symptom Profiles Amongst People Who Use Methamphetamine: What Do They Tell Us About Existing Diagnostic Categories?

Front Psychiatry 2018 19;9:578. Epub 2018 Nov 19.

St Vincent's Hospital, Fitzroy, VIC, Australia.

The inability to distinguish clearly between methamphetamine-related psychosis and schizophrenia has led to the suggestion that "methamphetamine psychosis" does not represent a distinct diagnostic entity but rather that the drug has triggered a vulnerability to schizophrenia. We tested this possibility by exploring the latent class structure of psychotic symptoms amongst people who use the drug and examining how these latent symptom profiles correspond to a diagnosis of schizophrenia. Latent class analysis was carried out on the lifetime psychotic symptoms of 554 current methamphetamine users, of whom 40 met the DSM-IV criteria for schizophrenia. Read More

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http://dx.doi.org/10.3389/fpsyt.2018.00578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262399PMC
November 2018
2 Reads

[Psychotic symptoms as a side-effect of omeprazole].

Tijdschr Psychiatr 2018;60(12):834-837

A 12-year-old girl with no psychiatric history developed psychotic symptoms, including formal thought disorder and delusional ideas after omeprazole was initiated. Given the co-occurrence of omeprazole initiation and the start of these symptoms, omeprazole was discontinued and replaced by ranitidine which led to immediate symptom reduction followed by complete remission. Although the proton pump inhibitor (ppi) omeprazole is considered safe and is commonly prescribed, it can cause rare major psychiatric side-effects. Read More

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March 2019
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A psychometric investigation of the Chinese version of the Internal, Personal and Situational Attributions Questionnaire (C-IPSAQ).

Transl Psychiatry 2018 11 28;8(1):256. Epub 2018 Nov 28.

Center for Psychiatric Rehabilitation of Boston University, Boston, MA, USA.

The IPSAQ is a self-administered instrument designed to evaluate individuals' attributional style (AS). The purpose of this study is to examine the psychometric properties of the Chinese version of the Internal, Personal and Situational Attributions Questionnaire (C-IPSAQ). We also investigate if patients with depression and patients with delusions exhibit attributional biases. Read More

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http://dx.doi.org/10.1038/s41398-018-0314-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261968PMC
November 2018
2 Reads

Exploratory comparison of auditory verbal hallucinations and other psychotic symptoms among youth with borderline personality disorder or schizophrenia spectrum disorder.

Early Interv Psychiatry 2018 Nov 28. Epub 2018 Nov 28.

Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia.

Objective: This study explored phenomenological aspects of auditory verbal hallucinations (AVH) and other psychotic symptoms among youth with borderline personality disorder (BPD).

Methods: Sixty-eight outpatients, aged 15 to 25 years, were categorized into three groups according to their primary Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnosis and AVH symptom profile; BPD + AVH (n = 23), schizophrenia spectrum disorder (SZ) + AVH (n = 22) and BPD with no AVH (n = 23).

Results: No differences in AVH were found between BPD + AVH and SZ + AVH. Read More

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http://dx.doi.org/10.1111/eip.12763DOI Listing
November 2018
4 Reads

From Evolutive Paranoia, by August Wimmer (1902): Part 2.

Authors:
Johan Schioldann

Hist Psychiatry 2019 Mar 26;30(1):116-124. Epub 2018 Nov 26.

University of Adelaide, Australia.

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http://journals.sagepub.com/doi/10.1177/0957154X18807632
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http://dx.doi.org/10.1177/0957154X18807632DOI Listing
March 2019
11 Reads