19,544 results match your criteria Defibrillation & Cardioversion


Defibrillation threshold of internal cardioversion prior to ablation predicts atrial fibrillation recurrence.

Clin Cardiol 2021 Jun 23. Epub 2021 Jun 23.

Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background: Many studies have reported the predictors of atrial fibrillation (AF) recurrence after persistent AF (peAF) ablation. However, the correlation between the atrial defibrillation threshold (DFT) for internal cardioversion (IC) and AF recurrence rate is unknown. Here we investigated the relationship between the DFT prior to catheter ablation for peAF and AF recurrence. Read More

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Protocol for a cohort study of the impact of the COVID-19 pandemic on the rate and incidence of bystander cardiopulmonary resuscitation (CPR) after out-of-hospital cardiac arrest.

Scand J Trauma Resusc Emerg Med 2021 Jun 21;29(1):82. Epub 2021 Jun 21.

Institute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany.

Background: Survival after out-of-hospital cardiac arrest (OHCA) is dependent on early recognition, early cardiopulmonary resuscitation (CPR) and early defibrillation. The purpose of CPR is to maintain some blood flow until the arrival of the emergency medical services (EMS). Our concern is that the COVID-19 pandemic has had a negative effect on the number of patients who get CPR before EMS arrival. Read More

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Can primary palliative care education change life-sustaining treatment intensity of older adults at the end of life? A retrospective study.

BMC Palliat Care 2021 Jun 21;20(1):84. Epub 2021 Jun 21.

Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Dongjiaominxiang No.1, Dongcheng District, Beijing, 100730, China.

Background: Palliative care education has been carried out in some hospitals and palliative care has gradually developed in mainland China. However, the clinical research is sparse and whether primary palliative care education influence treatment intensity of dying older adults is still unknown. This study aims to explore the changes to the intensity of end-of-life care in hospitalized older adults before and after the implementation of primary palliative care education. Read More

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Cardiac arrests in general practice clinics or witnessed by emergency medical services: a 20-year retrospective study.

Med J Aust 2021 Jun 14. Epub 2021 Jun 14.

NHMRC Centre of Research Excellence in Pre-hospital Emergency Care Australia and New Zealand (PEC-ANZ), Monash University, Melbourne, VIC.

Objective: To compare the frequency and outcomes of cardiac arrests in general practice clinics with those of paramedic-witnessed cardiac arrests.

Design, Setting: Retrospective study; analysis of Victorian Ambulance Cardiac Arrest Registry data, 1 January 2000 - 30 December 2019.

Participants: Patients with non-traumatic cardiac arrests whom emergency medical services staff attempted to resuscitate. Read More

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Microfibrillated cellulose films containing chitosan and tannic acid for wound healing applications.

J Mater Sci Mater Med 2021 Jun 12;32(6):67. Epub 2021 Jun 12.

Department of Paper sciences and engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.

The effectiveness of tannic acid as antimicrobial and wound healing for burns have been shown for a century; however, uncontrolled target dosage may result in undesirable side-effects. Remarkably, tannic acid polyphenols compounds crosslinked with polymeric materials produce a strong composite containing the beneficial properties of this tannin. However, investigation of the crosslink structure and its antibacterial and regenerative properties are still unknown when using nanocellulose by mechanical defibrillation; additionally, due to the potential crosslink structure with chitosan, its structure can be complex. Read More

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Ineffective implantable cardioverter-defibrillator shocks among patients on continuous left ventricular assist device support: Clinical characteristics and management.

Heart Rhythm O2 2020 Dec 6;1(5):336-340. Epub 2020 Nov 6.

Medstar Washington Hospital Center, Washington, DC.

Background: Placement of a left ventricular assist device (LVAD) has been described to compromise implantable cardioverter-defibrillator (ICD) defibrillation threshold (DFT). Elevated DFT will have negative consequences and increases the risk of ineffective ICD shocks, morbidity, and mortality. DFT testing is not routinely performed in clinical practice, despite this fact. Read More

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December 2020

Decline in physical activity in the weeks preceding sustained ventricular arrhythmia in women.

Heart Rhythm O2 2020 Oct 25;1(4):283-287. Epub 2020 Jun 25.

Department of Medicine, Cooper Medical School of Rowan University, Camden, New Jersey.

Background: Heightened risk of cardiac arrest following physical exertion has been reported. Among patients with an implantable defibrillator, an appropriate shock for sustained ventricular arrhythmia was preceded by a retrospective self-report of engaging in mild-to-moderate physical activity. Previous studies evaluating the relationship between activity and sudden cardiac arrest lacked an objective measure of physical activity and women were often underrepresented. Read More

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October 2020

Surgical Cardiac Sympathetic Denervation for Ventricular Arrhythmias: A Systematic Review.

Methodist Debakey Cardiovasc J 2021 Apr 25;17(1):24-35. Epub 2021 Mar 25.

Houston Methodist Hospital, Houston, Texas.

Ventricular arrhythmias are potentially life-threatening disorders that are commonly treated with medications, catheter ablation and implantable cardioverter defibrillator (ICD). Adult patients who continue to be symptomatic, with frequent ventricular arrhythmia cardiac events or defibrillation from ICD despite medical treatment, are a challenging subgroup to manage. Surgical cardiac sympathetic denervation has emerged as a possible treatment option for people refractory to less invasive medical options. Read More

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Asymptomatic ventricular fibrillation in continuous flow left-ventricular assist device.

Am J Emerg Med 2021 May 29;49:130-132. Epub 2021 May 29.

University of Virginia Health System, Department of Emergency Medicine, 1215 Lee Street, Charlottesville, VA 22901, United States. Electronic address:

Left ventricular assist devices (LVADs) have increased survival for heart failure patients. Individuals with LVADs are a growing patient population with frequent complications and Emergency Department (ED) visits. A 50-year-old female presented to the ED due to a low flow alarm on her LVAD. Read More

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Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes.

JCI Insight 2021 Jun 8;6(11). Epub 2021 Jun 8.

Sohnis Research Laboratory for Cardiac Electrophysiology and Regenerative Medicine, the Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa, Israel, Haifa, Israel.

Abnormal action potential (AP) properties, as occurs in long or short QT syndromes (LQTS and SQTS, respectively), can cause life-threatening arrhythmias. Optogenetics strategies, utilizing light-sensitive proteins, have emerged as experimental platforms for cardiac pacing, resynchronization, and defibrillation. We tested the hypothesis that similar optogenetic tools can modulate the cardiomyocyte's AP properties, as a potentially novel antiarrhythmic strategy. Read More

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How to get the optimal defibrillation lead parameters using myocardial perfusion scintigraphy in patients with coronary artery disease.

Int J Cardiovasc Imaging 2021 Jun 7. Epub 2021 Jun 7.

Department of Surgical Arrhythmology and Cardiac Pacing, Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Kievskaya st., 111a, Tomsk, Russian Federation, 634012.

The conventional criteria for a defibrillation lead (DL) implantation don't take into account presence of scar or deep ischemia in the myocardium. This may impair a proper functioning of the DL. We sought to optimize the DL implantation placement using rest myocardial perfusion scintigraphy (MPS), which allow detecting areas of myocardial hypoperfusion (MH). Read More

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Effect of Amplitude Spectral Area on Termination of Fibrillation and Outcomes in Pediatric Cardiac Arrest.

J Am Heart Assoc 2021 Jun 5;10(12):e020353. Epub 2021 Jun 5.

Department of Anesthesiology and Critical Care, and The Center for Simulation, Advanced Education, and Innovation The Children's Hospital of Philadelphia Philadelphia PA.

Background Amplitude spectral area (AMSA) predicts termination of fibrillation (TOF) with return of spontaneous circulation (ROSC) and survival in adults but has not been studied in pediatric cardiac arrest. We characterized AMSA during pediatric cardiac arrest from a Pediatric Resuscitation Quality Collaborative and hypothesized that AMSA would be associated with TOF and ROSC. Methods and Results Children aged <18 years with cardiac arrest and ventricular fibrillation were studied. Read More

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[Paediatric Life Support].

Notf Rett Med 2021 Jun 2:1-70. Epub 2021 Jun 2.

Paediatric Emergency Medicine, Faculty of Medicine Imperial College, Imperial College Healthcare Trust NHS, London, Großbritannien.

The European Resuscitation Council (ERC) Paediatric Life Support (PLS) guidelines are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations of the International Liaison Committee on Resuscitation (ILCOR). This section provides guidelines on the management of critically ill or injured infants, children and adolescents before, during and after respiratory/cardiac arrest. Read More

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[Basic life support].

Notf Rett Med 2021 Jun 2:1-20. Epub 2021 Jun 2.

Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, CV4 7AL Coventry, Großbritannien.

The European Resuscitation Council has produced these basic life support guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include cardiac arrest recognition, alerting emergency services, chest compressions, rescue breaths, automated external defibrillation (AED), cardiopulmonary resuscitation (CPR) quality measurement, new technologies, safety, and foreign body airway obstruction. Read More

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Flecainide-Induced Atrial Flutter With 1:1 Conduction Complicated by Ventricular Fibrillation After Electrical Cardioversion.

Tex Heart Inst J 2021 06;48(2)

Department of Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania.

Flecainide, a widely prescribed class IC agent used to treat atrial arrhythmias, can in rare cases cause 1:1 atrial flutter with rapid conduction. We describe the case of a 59-year-old man who was on a maintenance regimen of flecainide for refractory atrial fibrillation. When 1:1 atrial flutter with rapid conduction developed, emergency medical technicians attempted synchronized cardioversion, which caused ventricular fibrillation necessitating defibrillation. Read More

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Are Three Weeks of Oral Anticoagulation Sufficient for Safe Cardioversion in Atrial Fibrillation?

Medicina (Kaunas) 2021 May 31;57(6). Epub 2021 May 31.

Department of Internal Diseases "Prof. St. Kirkovich", Medical University of Sofia, 1431 Sofia, Bulgaria.

Patients with atrial fibrillation (AF), lasting >48 h, considered for cardioversion, are recommended ≥3 weeks of oral anticoagulation before sinus rhythm restoration because of high risk of development of left atrial thrombosis (LAT) and stroke. However, the optimal duration of anticoagulation in the presence of overt LAT is unknown. An open-label study aimed to investigate the prevalence of spontaneous echo contrast (SEC) and LAT before and after 3 weeks of direct oral anticoagulant (DOAC) treatment. Read More

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Detection of Ventricular Fibrillation Based on Ballistocardiography by Constructing an Effective Feature Set.

Sensors (Basel) 2021 May 19;21(10). Epub 2021 May 19.

Center for Biomedical Engineering, School of Information Science and Technology, Fudan University, Shanghai 200433, China.

Ventricular fibrillation (VF) is a type of fatal arrhythmia that can cause sudden death within minutes. The study of a VF detection algorithm has important clinical significance. This study aimed to develop an algorithm for the automatic detection of VF based on the acquisition of cardiac mechanical activity-related signals, namely ballistocardiography (BCG), by non-contact sensors. Read More

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The Defibrillation Conundrum: New Insights into the Mechanisms of Shock-Related Myocardial Injury Sustained from a Life-Saving Therapy.

Int J Mol Sci 2021 May 8;22(9). Epub 2021 May 8.

Service de Cardiologie, Hôpital Trousseau, Université de Tours, 37044 Tours, France.

Implantable cardiac defibrillators (ICDs) are recommended to prevent the risk of sudden cardiac death. However, shocks are associated with an increased mortality with a dose response effect, and a strategy of reducing electrical therapy burden improves the prognosis of implanted patients. We review the mechanisms of defibrillation and its consequences, including cell damage, metabolic remodeling, calcium metabolism anomalies, and inflammatory and pro-fibrotic remodeling. Read More

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Successful Postnatal Cardiopulmonary Resuscitation Due to Defibrillation.

Children (Basel) 2021 May 20;8(5). Epub 2021 May 20.

Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, 8036 Graz, Austria.

An asphyxiated term neonate required postnatal resuscitation. After six minutes of cardio-pulmonary resuscitation (CPR) and two doses of epinephrine, spontaneous circulation returned, but was shortly followed by ventricular fibrillation. CPR and administration of magnesium, calcium gluconate, and sodium bicarbonate did not improve the neonate's condition. Read More

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Magnetic Resonance Imaging-Guided Cardiac Catheterization Evacuation Drills.

Crit Care Nurse 2021 Jun;41(3):e19-e26

Russell R. Cross is an associate professor of pediatrics, George Washington University School of Medicine, and Medical Director of inpatient cardiology and an advanced imaging cardiologist, Division of Cardiology, Children's National Hospital.

Background: The interventional cardiac magnetic resonance imaging suite combines a cardiac catheterization x-ray laboratory with a magnetic resonance imaging suite. At the study institution, interventional cardiac magnetic resonance imaging procedures (ie, magnetic resonance imaging-guided cardiac catheterizations) have been performed under institutional review board-approved research protocols since 2015. Because the workplace incorporates x-ray and magnetic resonance imaging in a highly technical environment, education about the importance of magnet safety is crucial to ensure the safety of patients and staff. Read More

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Atrial Fibrillation.

JAMA 2021 06;325(21):2218

Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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Emergency Medical Services Responses to Out-of-Hospital Cardiac Arrest and Suspected ST-Segment-Elevation Myocardial Infarction During the COVID-19 Pandemic in Los Angeles County.

J Am Heart Assoc 2021 06 1;10(12):e019635. Epub 2021 Jun 1.

Division of Cardiology Department of Medicine University of California Los Angeles CA.

Background Public health emergencies may significantly impact emergency medical services responses to cardiovascular emergencies. We compared emergency medical services responses to out-of-hospital cardiac arrest (OHCA) and ST-segment‒elevation myocardial infarction (STEMI) during the 2020 COVID-19 pandemic to 2018 to 2019 and evaluated the impact of California's March 19, 2020 stay-at-home order. Methods and Results We conducted a population-based cross-sectional study using Los Angeles County emergency medical services registry data for adult patients with paramedic provider impression (PI) of OHCA or STEMI from February through May in 2018 to 2020. Read More

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Implantable Cardioverter-Defibrillator Shocks During COVID-19 Outbreak.

J Am Heart Assoc 2021 06 28;10(11):e019708. Epub 2021 May 28.

Cardiac Rhythm Heart FailureMedtronic, Inc Minneapolis MN.

Background COVID-19 was temporally associated with an increase in out-of-hospital cardiac arrests, but the underlying mechanisms are unclear. We sought to determine if patients with implantable defibrillators residing in areas with high COVID-19 activity experienced an increase in defibrillator shocks during the COVID-19 outbreak. Methods and Results Using the Medtronic (Mounds View, MN) Carelink database from 2019 and 2020, we retrospectively determined the incidence of implantable defibrillator shock episodes among patients residing in New York City, New Orleans, LA, and Boston, MA. Read More

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Assessment of Canadian Public Automated External Defibrillator Registries.

CJC Open 2021 Apr 26;3(4):504-509. Epub 2020 Dec 26.

Department of Emergency Medicine, McGill University, Montréal, Québec, Canada.

Background: Public automated external defibrillator (AED) registries aim to increase layperson defibrillation for victims of out-of-hospital cardiac arrest. This study aims to characterize Canadian AED registries and the process by which these databases are updated and used.

Methods: A survey was administered to representatives from each eligible AED registry. Read More

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A case report of an elderly male with isolated coronary sinus atrial septal defect.

Eur Heart J Case Rep 2021 May 17;5(5):ytab152. Epub 2021 May 17.

Department of Thoracic and Cardiovascular Surgery, Osaka Medical College, 2-7 Daigaku-Machi, Takatsuki, Osaka 569-0801, Japan.

Background: Isolated coronary sinus atrial septal defect (CSASD) is a rare congenital cardiac anomaly, comprising <1% of atrial septal defects. Elderly patients with this anomaly are even more uncommon and sometimes overlooked.

Case Summary: A 73-year-old man with a history of electrical defibrillation therapy for atrial flutter presented with worsening exertional dyspnoea. Read More

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Cerebral and myocardial mitochondrial injury differ in a rat model of cardiac arrest and cardiopulmonary resuscitation.

Biomed Pharmacother 2021 Aug 18;140:111743. Epub 2021 May 18.

Weil Institute of Emergency and Critical Care Research, Virginia Commonwealth University, Richmond, VA, USA; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA, USA; Department of Emergency Medicine, Virginia Commonwealth University Health System, Richmond, VA, USA. Electronic address:

Brain mitochondria are more sensitive to global ischemia compared to heart mitochondria. Complex I in the electron transport chain (ETC) is sensitive to ischemic injury and is a major control point of the rate of ADP stimulated oxygen consumption. The purpose of this study was to explore whether changes in cerebral and myocardial mitochondria differ after cardiac arrest. Read More

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How to improve automated external defibrillator placement for out-of-hospital cardiac arrests: A case study.

PLoS One 2021 20;16(5):e0250591. Epub 2021 May 20.

Emergency Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

Introduction: In out-of-hospital cardiac arrests (OHCAs), the use of an automatic external defibrillator (AED) by a bystander remains low, as AEDs may be misplaced with respect to the locations of OHCAs. As the distribution of historical OHCAs is potentially predictive of future OHCA locations, the purpose of this study is to assess AED positioning with regard to past locations of OHCAs, in order to improve the efficiency of public access defibrillation programs.

Methods: This is a retrospective observational study from 2014 to 2018. Read More

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Rapid Cycle Deliberate Practice Improves Retention of Pediatric Resuscitation Skills Compared With Postsimulation Debriefing.

Simul Healthc 2021 Mar 13. Epub 2021 Mar 13.

From the Section of Emergency Medicine, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX.

Introduction: Rapid cycle deliberate practice (RCDP) for teaching team-based resuscitation is associated with similar improvements in immediate performance as compared with postsimulation debriefing (PSD). Limited studies compare skill retention between these 2 modalities. Our objective was to compare retention of team leader performance in residents trained with RCDP versus PSD. Read More

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Resuscitative endovascular balloon occlusion of the aorta vs epinephrine in the treatment of non-traumatic cardiac arrest in swine.

Ann Intensive Care 2021 May 17;11(1):81. Epub 2021 May 17.

Univ Paris Est Créteil, INSERM, IMRB, 94010, Créteil, France.

Background: The administration of epinephrine in the management of non-traumatic cardiac arrest remains recommended despite controversial effects on neurologic outcome. The use of resuscitative endovascular balloon occlusion of the aorta (REBOA) could be an interesting alternative. The aim of this study was to compare the effects of these 2 strategies on return of spontaneous circulation (ROSC) and cerebral hemodynamics during cardiopulmonary resuscitation (CPR) in a swine model of non-traumatic cardiac arrest. Read More

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