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Acta Clin Croat 2021 Dec;60(4):773-776

1Department of Anesthesiology and Intensive Therapy, Slovenj Gradec General Hospital, Slovenj Gradec, Slovenia; 2Department of Gynecology and Obstetrics, Slovenj Gradec General Hospital, Slovenj Gradec, Slovenia.

Deep septic pelvic thrombophlebitis is a rare but potentially devastating complication in the puerperium. Early diagnosis and aggressive treatment of this postpartum complication is essential. We report a case of a 23-year-old multipara, who presented with persistent high fever and abdominal pain two days after delivery. Read More

Exp Ther Med 2022 Jul 17;24(1):449. Epub 2022 May 17.

Clinic of Dermatology, County Emergency Hospital of Sibiu, 550245 Sibiu, Romania.

The role of hyperhomocysteinemia (HH) in the etiopathogenetics of systemic thrombotic events has been confirmed by numerous studies. However, it has been insufficiently studied as an etiopathogenic factor in chronic venous insufficiency (CVI). The present prospective study included 166 patients with CVI at stages C3-C6. Read More

Cir Cir 2022 ;90(3):427-428

CB-Xpert Laboratorio de Patología Clínica, Miahuatlán de Porfirio Díaz, Oaxaca. México.

Breast Dis 2022 ;41(1):273-278

Division of Hospital Medicine, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, Japan.

Background: Mondor disease is superficial thrombophlebitis of the thoracoabdominal wall, mid-upper arm, and penis. Although it is usually a benign disease requiring no specific treatment, little is known about this disease owing to its rarity.

Objective: The aim of this retrospective observational study was to investigate the epidemiology and prognosis of Mondor disease. Read More

J Vasc Access 2022 May 24:11297298221095778. Epub 2022 May 24.

Department of Infective Diseases, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Introduction: Although several guidelines recommend that prolonged administration of vancomycin should be preferably carried out by a central venous access, vancomycin is often given peripherally. Whether such risk may be affected by different modalities of administration in terms of dilution and time of infusion, it is a matter of controversy.

Methods: This single-center prospective study enrolled all consecutive patients requiring prolonged intravenous infusion of vancomycin (1 g/day) using long peripheral cannula "mini-midline. Read More

J Belg Soc Radiol 2022 27;106(1):24. Epub 2022 Apr 27.

Presbyterian Medical Center, KR.

Radiologists need to be familiar with that ovarian vein thrombosis can occur as a complication of urinary tract infection. Ovarian vein thrombosis is a rare disease in which a majority of cases occur during the postpartum period. There are few case reports for ovarian vein thrombosis associated with urinary tract infection in non-postpartum women. Read More

J Radiol Case Rep 2022 Mar 1;16(3):1-14. Epub 2022 Mar 1.

Department of Radiology, National Hospital Organization/Osaka National Hospital, Osaka, Japan.

Septic thrombi, such as those observed in pylephlebitis and Lemierre's syndrome, are characterized by portal vein thrombosis and venous thrombosis with bacterial infection. Although radiographic findings of septic thrombus on contrast-enhanced computed tomography have been well described, no report has described the characteristics of non-contrast-enhanced computed tomography. We describe a case series of septic thrombophlebitis exhibiting intravascular hypo- and hyper-attenuation on non-contrast-enhanced computed tomography. Read More

West Afr J Med 2022 Apr;39(4):425-428

Department of Surgery, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria.

Background: Mondor's disease (MD) is a rare cause of chest pain, characterized by thrombophlebitis of the subcutaneous veins of the anterolateral thoracoabdominal wall. It is a benign, self-limiting condition that is often underdiagnosed due to lack of knowledge of the condition. Although the exact aetiology is unclear, several predisposing factors, including excessive physical activity have been postulated. Read More

Pediatr Emerg Care 2022 Apr 27. Epub 2022 Apr 27.

Pediatric Emergency Medicine, Medical University of South Carolina, Charleston, SC.

Septic thrombophlebitis represents a rare but serious collection of diseases, which carry a high risk of morbidity and mortality requiring prompt and aggressive treatment. Diagnosis centers on identification of thrombus along with clinical and microbiologic data. We present a case where point-of-care ultrasound was used to diagnose septic thrombophlebitis of the internal jugular vein and expedite appropriate therapy. Read More

J Dermatol 2022 Apr 17. Epub 2022 Apr 17.

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan.

Behçet's disease (BD) has a heterogeneous spectrum of disease manifestations featuring the involvement of different organs and can be characterized with different symptoms depending on the clinical department in charge. We retrospectively reviewed BD patients seen at our hospital and investigated the presence of neutrophils producing neutrophil extracellular traps (NET) in those patients. Immunolabeling of myeloperoxidase and histone citrullination proteins was performed on skin biopsies from three BD patients who had skin biopsy-proven superficial vein thrombophlebitis in their erythema nodosum-like lesions. Read More

Vasa 2022 May 13;51(3):182-189. Epub 2022 Apr 13.

Department of Angiology, University Hospital Zurich, Switzerland.

Treatment of pelvic venous disorders (PVD) including pelvic congestion syndrome (PCS) are often delayed due to its varying clinical manifestations. Patient referral was based on a literature- and personal experience-derived clinical "PCS screening score" (higher score points indicate greater likelihood with a maximum score of 10 points). We studied consecutive women who were (i) referred for vascular assessment and treatment to the University Hospital Zurich (2017-2021), (ii) had a PCS score ≥3 points, (iii) had evidence of obstructive or non-obstructive PVD by duplex sonography or cross-sectional imaging, and (iv) underwent endovascular therapy. Read More

JAMA Surg 2022 May;157(5):395-404

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

Importance: Endovenous thermal ablations (ETAs) are recommended as first-line treatment for truncal vein reflux, have a short recovery time, and are cost-effective. However, ETAs are associated with discomfort during tumescent anesthesia infiltration. To minimize discomfort, nonthermal, nontumescent ablation techniques had emerged in the form of mechanochemical ablation (MOCA) and cyanoacrylate adhesive injection (CAE). Read More

Wilderness Environ Med 2022 06 31;33(2):169-178. Epub 2022 Mar 31.

Division of Hematology-Medical Oncology, Oregon Health & Science University, Portland, Oregon. Electronic address:

Introduction: Long-distance travel is assumed to be a risk factor for venous thromboembolism (VTE). However, the available data have not clearly demonstrated the strength of this relationship, nor have they shown evidence for the role of thromboprophylaxis.

Methods: We performed a systematic review of the literature. Read More

Intern Med 2022 05 19;61(10):1631. Epub 2022 Mar 19.

Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Japan.

Intractable Rare Dis Res 2022 Feb;11(1):37-39

Operative Unit of Otorhinolaryngology, "Dimiccoli" General Hospital, Barletta, Italy.

Lemierre's syndrome (LS) is a "forgotten" condition characterized by septic thrombophlebitis of the jugular vein that follows an otolaryngological infection. Fusobacterium necrophorum is the aetiological agent responsible for the syndrome in adolescents and young adults whereas in older people even common bacteria are involved. Complications arise from spreading of septic emboli distally, to the brain, lungs, bones and internal organs everywhere in the body. Read More

Ann Med Surg (Lond) 2022 Mar 9;75:103276. Epub 2022 Feb 9.

Faculty of Medicine and Pharmacy, Mohammed I University, Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, Morocco.

Introduction: Hyperchylomicronemia is a disorder of lipid's metabolism that can present fatal complications such us such venous or arterial thrombosis, pancreatitis, and cardiovascular incidents.

Case Presentation: In this report case we report a 4months old patient who was admitted in the emergency room for hypotonia and during the blood sampling we were surprised by the macroscopic latescent aspect of the blood. During the investigations we found that the patient had a fatty cerebral venous thrombosis that revealed hyperchylomicronemia. Read More

Cureus 2022 Jan 16;14(1):e21297. Epub 2022 Jan 16.

Infectious Disease, Howard University Hospital, Washington DC, USA.

Pylephlebitis is defined as suppurative thrombophlebitis of the portal venous system. It is a rare condition that can be fatal if left untreated. It is usually caused by polymicrobial bacteria, most commonly and genus. Read More

Nanoscale 2022 Mar 7;14(9):3545-3553. Epub 2022 Mar 7.

GBA National Institute for Nanotechnology Innovation, Guangzhou, Guangdong 510700, P.R. China.

Superficial thrombophlebitis is one of the most significant complications of superficial vein thrombosis. Rapid imaging and mapping with high resolution is particularly important for accurate diagnosis so as to carry out treatment as soon as possible. Ultrasound imaging technology has been used extensively because of the low-cost, minimal invasiveness, and convenient application in clinical practice. Read More

Br J Hosp Med (Lond) 2022 Jan 11;83(1):1-4. Epub 2022 Jan 11.

Department of Surgery, York Teaching Hospital NHS Foundation Trust, York, UK.

Anaerobe 2022 Jun 2;75:102532. Epub 2022 Feb 2.

Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

F. necrophorum, a gram-negative obligate anaerobe, causes pharyngotonsillitis, peritonsillar abscess and the Lemierre Syndrome as well as other significant infections. Clinical information on this bacterium has increased dramatically over the past 20 years, yet no standard guidance exists for treating these infections. Read More

Cureus 2021 Dec 25;13(12):e20690. Epub 2021 Dec 25.

Medicine, King Fahad Medical City, Riyadh, SAU.

Deep venous thrombosis (DVT) is the most common cause of unilateral lower limb swelling. Common differential diagnosis includes superficial thrombophlebitis and ruptured Baker's cyst. DVT is one of the most common complications diagnosed following lower extremity orthopedic surgery. Read More

Yakugaku Zasshi 2022 ;142(2):189-193

Department of Infectious Diseases, St. Marianna University School of Medicine Hospital.

We report a rare case of suppurative thrombophlebitis of the posterior neck caused by Streptococcus constellatus. A 69-year-old female patient was admitted to the hospital with neck pain and fever, which had persisted for 16 days prior to hospitalization. On day 1 (day of admission), blood cultures (later identifying S. Read More

Thorax 2022 03 7;77(3):314-316. Epub 2022 Jan 7.

Respiratory Medicine, Frimley Health NHS Foundation Trust, Frimley, UK.

Neurologia (Engl Ed) 2022 Mar 29;37(2):154-156. Epub 2021 Dec 29.

Servicio de Neurología, Hospital Universitario de La Princesa, Madrid, Spain.

J Vasc Interv Radiol 2022 04 24;33(4):445-450. Epub 2021 Dec 24.

Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China. Electronic address:

Purpose: To evaluate the effectiveness and safety of fluoroscopy-guided percutaneous high ligation (FPHL) combined with fluoroscopy-guided foam sclerotherapy (FGFS) to treat varicose veins of the great saphenous veins (GSVs).

Materials And Methods: This was a retrospective study of 113 patients (mean age, 62.1 ± 10. Read More

BMC Cardiovasc Disord 2021 12 9;21(1):592. Epub 2021 Dec 9.

Department of Internal Medicine/Division of Cardiology, UCLA, 757 Westwood Ave, Ste 2125, Los Angeles, CA, 90095, USA.

Background: COVID-19 and Fontan physiology have each been associated with an elevated risk of venous thromboembolism (VTE), however little is known about the risks and potential consequences of having both.

Case Presentation: A 51 year old male with tricuspid atresia status post Fontan and extracardiac Glenn shunt, atrial flutter, and sinus sick syndrome presented with phlegmasia cerulea dolens (PCD) of the left lower extremity in spite of supratherapeutic INR in the context of symptomatic COVID-10 pneumonia. He was treated with single session, catheter directed mechanical thrombectomy that was well-tolerated. Read More

Mayo Clin Proc 2021 12;96(12):3178-3179

Department of Vascular and Endovascular Surgery, Hôpital Louis Pradel, Hospices Civils de Lyon, Lyon, France.

Clin Med (Lond) 2021 11;21(6):e664-e666

Glan Clwyd Hospital, Bodelwyddan, UK.

A 65-year-old man, who was previously fit and well with no known medical comorbidities, was admitted with symptoms of dysuria, urinary frequency, pyrexia, chills and lethargy. His vitals showed that he was hypotensive, tachycardic and pyrexial. Urine dip was heavily positive for leukocytes and nitrites and had markedly elevated inflammatory markers and mild acute kidney injury. Read More

Orbit 2021 Nov 30:1-4. Epub 2021 Nov 30.

Elson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.

Patients with COVID-19 have been reported to have elevated coagulation factors, which is a well-documented cause of venous thromboembolism events such as deep vein thrombosis and pulmonary embolism. Other venous thrombotic events, however, such as cavernous sinus thrombosis (CST) have been less commonly observed, specifically in combination with primary orbital cellulitis. Due to its unique anatomic location, the cavernous sinus is susceptible to thrombophlebitis processes including septic thrombosis and thrombosis most commonly from sinusitis. Read More

J Clin Med 2021 Nov 19;10(22). Epub 2021 Nov 19.

Department of Cardiology, Cardiology I, University Medical Center Mainz (Johannes Gutenberg-University Mainz), 55131 Mainz, Germany.

Background: Venous thromboembolism is a frequent complication and an important cause of death in patients with paralysis. We aimed to investigate predictors of pulmonary embolism (PE) and the impact of PE on the survival of patients with paralysis in comparison to those with deep venous thrombosis or thrombophlebitis (DVT).

Methods: Patients were selected by screening the German nationwide inpatient sample (2005-2017) for paralysis, and were stratified for venous thromboembolism (VTE) and the VTE-sub-entity PE (ICD-code I26). Read More