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Childs Nerv Syst 2019 Feb 18. Epub 2019 Feb 18.

Division of Pediatric Neurosurgery, Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Standford, 94305, CA, USA.

Parapharyngeal infection is the most common deep neck space infection in children and, in rare instances, can result in bony destruction of the cervical spine. We report one such case that required occipital to cervical fusion and halo-vest fixation. We also review the literature and discuss the etiology, diagnosis, and treatment options for managing pediatric cervical bony destruction secondary to infection. Read More

Br J Oral Maxillofac Surg 2019 Feb 12. Epub 2019 Feb 12.

Maxillofacial surgery Trainees Research Collaborative, Queen Elizabeth University Hospital, Glasgow.

The role of corticosteroids in the management of cervicofacial infections continues to cause controversy. Systemic anti-inflammatory and immunomodulatory effects that reduce swelling and improve symptoms in the head and neck may make these agents an effective addition to the antibiotics used and to surgical management, although this same effect may dull the physiological response to infection, and allow infections to progress. We have systematically reviewed the evidence for the use of corticosteroids in common cervicofacial infections following the PRISMA guidelines. Read More

Am J Sports Med 2019 Feb 7:363546518820528. Epub 2019 Feb 7.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background:: Previous studies on periacetabular osteotomy (PAO) reported complication and reoperation rates of 5.9% and 10%, respectively. Hip arthroscopy is increasingly utilized as an adjunct procedure to PAO to precisely treat associated intra-articular pathology. Read More

Head Neck 2019 Jan 30. Epub 2019 Jan 30.

National Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.

Background: The association between diet and head and neck cancer (HNC) survival is unclear.

Methods: Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.

Results: Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Read More

J Med Ultrasound 2018 Oct-Dec;26(4):215-217. Epub 2018 Dec 14.

Department of Emergency, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

A peripherally inserted central venous catheter (PICC) has been widely applied to central venous assess. There were some known complications such as phlebitis, leakage, blockage, dislodgment, breakage, or malposition of PICC. Catheter migration was assessed by using chest radiograph or administering contrast medium. Read More

JAMA Netw Open 2018 Nov 2;1(7):e185275. Epub 2018 Nov 2.

Division of Functional Neurosurgery of Institute of Psychiatry, Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.

Importance: Deep brain stimulation (DBS) has been investigated for treatment of morbid obesity with variable results. Patients with Prader-Willi syndrome (PWS) present with obesity that is often difficult to treat.

Objective: To test the safety and study the outcome of DBS in patients with PWS. Read More

Acta Radiol 2019 Jan 12:284185118822628. Epub 2019 Jan 12.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Background: Percutaneous transesophageal gastrotubing (PTEG) is an alternative means of access into the stomach when conventional transabdominal gastric access is not possible.

Purpose: To describe the early clinical experience, technical feasibility, safety, and efficacy of the hydro-dissection assisted puncture of an esophageal balloon used for PTEG.

Material And Methods: A retrospective review was conducted of six, consecutive patients with feeding problems and who were treated with hydro-dissection assisted puncture of an esophageal balloon for PTEG. Read More

Clin Oral Investig 2019 Jan 8. Epub 2019 Jan 8.

Department of Oral & Maxillofacial Plastic Surgery, University hospital Bonn, Sigmund-Freud-Strasse 25, 53127, Bonn, Germany.

Objectives: Aim of this study was to investigate conditions and predisposing factors for head and neck infection progress regarding the length of stay (LOS) in hospital, with special emphasis on the time of removal of the odontogenic infection focus.

Material And Methods: A 3-year retrospective study reviewed hospital records of 248 subjects who were treated under inpatient conditions with severe odontogenic infections who received surgical incisions, drainage, and intravenous (IV) antibiotics. Outcomes measured included age, gender, involved fascial spaces, LOS, number of infected spaces, antibiotics administered, and comorbidities. Read More

Front Surg 2018 10;5:75. Epub 2018 Dec 10.

Department of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.

Infected "mycotic" Aneurysm (IA) of the extracranial carotid artery is a rare condition that can be fatal if mistaken for other pathology. An 83-year-old man presented with a mass on the neck initially suspected malignant. Weeks later it grew rapidly and was found to be an IA, thus requiring acute surgery. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1366-1373

East War Zone Hospital of PLA, Research Institute of General Surgery, Nanjing 210002, China.

Objective: To determine the incidence of surgical site infection (SSI) after abdominal surgery and to further evaluate the related risk factors of SSI in China.

Methods: The multicenter cross-sectional study collected clinical data of all adult patients who underwent abdominal surgery from May 1, 2018 to May 31, 2018 in 30 domestic hospitals, including basic information, perioperative parameters, and incisional microbial culture results. The primary outcome was the incidence of SSI within postoperative 30 days. Read More

Zhongguo Gu Shang 2018 Dec;31(12):1100-1103

Department of Joint Surgery, Ningbo No.6 Hospital, Ningbo 351000, Zhejiang, China.

Objective: To analyze and evaluate the clinical outcomes of enhanced recovery after surgery(ERAS) for hemiarthroplasty for the treatment of femoral neck fractures in elderly patients.

Methods: From January 2015 to December 2016, 466 patients with femoral neck fractures were admitted in our department. Among them, 154 patients were more than 80 years old, with an average age of (83. Read More

BMC Musculoskelet Disord 2018 Dec 21;19(1):448. Epub 2018 Dec 21.

BG University Hospital Bergmannsheil, Bochum, Germany.

Background: Nonunions of the subtrochanteric region of the femur after previous intramedullary nailing can be difficult to address. Implant failure and bone defects around the implant significantly complicate the therapy, and complex surgical procedures with implant removal, extensive debridement of the nonunion site, bone grafting and reosteosynthesis usually become necessary. The purpose of this study was to evaluate the records of a series of patients with subtrochanteric femoral nonunions who were treated with dynamic condylar screws (DCS) regarding their healing rate, subsequent revision surgeries and implant-related complications. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Dec;32(12):1567-1571

Department of Head and Neck Surgery, Cancer Hospital of Shantou University Medical College, Shantou Guangdong, 515031, P.R.China.

Objective: To evaluate the reliability and effectiveness of a deep circumflex iliac artery based iliac-internal oblique musculofascial chimeric flap (DCIA-IIOF) in reconstruction of complex oromandibular defect.

Methods: Between January 2010 and December 2015, DCIA-IIOFs were used to repair complex oromandibular defects in 11 patients. There were 8 males and 3 females, with an age of 27-75 years (median, 56 years). Read More

BMC Neurol 2018 Dec 17;18(1):208. Epub 2018 Dec 17.

Department of Neurology, the Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian City, 116027, Liaoning Province, China.

Background: We reported a case of an adult that presented Guillain-Barré syndrome (GBS) after bacterial meningitis which was secondary to chronic suppurative otitis media (CSOM). To our knowledge, this is the first case involving an adult presenting with GBS following bacterial meningitis.

Case Presentation: A 46-year man with type 2 diabetes and otitis media (OM) suffered with fever, headache, and vomiting for 6 days. Read More

FASEB J 2018 Dec 14:fj201800695RR. Epub 2018 Dec 14.

Department of Otolaryngology, School of Medicine, Ajou University, Suwon, South Korea.

The use of nonthermal atmospheric plasma (NTP) in the biomedical field has recently expanded into cell death induction in cancer, infection prevention, inflammation treatment, and wound-healing enhancement. NTP has been demonstrated to enhance skin and muscle regeneration, but its effects on tissue regeneration, following deep tissue or muscle damage, remains underinvestigated. In this study, we determined the effects of NTP on muscle differentiation and the mechanisms of NTP's contribution to differentiation and regeneration. Read More

Arab J Urol 2018 Dec 5;16(4):411-416. Epub 2018 Jul 5.

Department of Urology and Men's Health, Al Garhoud Private Hospital, Dubai, United Arab Emirates.

Objectives: To report our experience with the emerging technique of thulium laser enucleation of the prostate (ThuLEP) for the treatment for prostate hyperplasia.

Patients And Methods: Our inclusion criteria were an International Prostate Symptom Score (IPSS) of >15 and a quality-of-life (QoL) score of >3 in patients with confirmed bladder outflow obstruction, no longer responsive to medical therapy, with a significant post-void residual urine volume (PVR; >100 mL), with or without recurrent urinary tract infection and/or acute urinary retention. Patients with neurogenic bladder, urethral strictures, bladder stones, and previously failed transurethral prostate surgery were excluded. Read More

Oral Radiol 2018 Jan 20;34(1):83-87. Epub 2017 Mar 20.

Department of Oral Radiology, Osaka Dental University, 1-5-17, Otemae, Chuo-ku, Osaka, 540-0008, Japan.

Cellulitis accompanied by gas gangrene is a rapidly-spreading and potentially fatal infection. Here, we present a case of gas gangrene in the deep spaces of the head and neck in an elderly woman, diagnosed by computed tomography (CT). An 86-year-old woman with Alzheimer's disease, hypertension, hyperlipidemia, and osteoporosis was referred to our institute by her local dentist. Read More

Scand J Surg 2018 Nov 25:1457496918812226. Epub 2018 Nov 25.

2 Department of Orthopedics and Traumatology, Central Finland Hospital, Jyväskylä, Finland.

Background And Aims:: Hemiarthroplasty is a common method of treating displaced femoral neck fractures, especially among elderly non-active patients with frailty syndrome. Complications arising from the use of a modern, modular hemiendoprosthesis via a posterior approach have been poorly reported in this population. The aim of this study was to evaluate complications and mortality associated with the use of Lubinus sp II cemented, unipolar hemiarthroplasty prosthesis and posterior approach during a 9-year follow-up. Read More

Br J Oral Maxillofac Surg 2018 Dec 22;56(10):962-967. Epub 2018 Nov 22.

Department of Otolaryngology, Chiang Mai University Hospital, Chiang Mai, 50200, Thailand. Electronic address:

We retrospectively studied the clinical features, complications, and outcomes of deep neck infections in 31 adult patients with the human immunodeficiency virus (HIV) (HIV group) and 192 patients without (non-HIV group). In the HIV group, the cause was more likely to be odontogenic (21 (68%) compared with 90 (47%); odds ratio (OR) 2.38; 95% CI 1. Read More

Biomed Opt Express 2018 Nov 23;9(11):5667-5677. Epub 2018 Oct 23.

Arkansas Nanomedicine Center, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.

Blood clotting is a serious clinical complication of many medical procedures and disorders including surgery, catheterization, transplantation, extracorporeal circuits, infections, and cancer. This complication leads to high patient morbidity and mortality due to clot-induced pulmonary embolism, stroke, and in some cases heart attack. Despite the clear medical significance, little progress has been made in developing the methods for detection of circulating blood clots (CBCs), also called emboli. Read More

Emerg Med Clin North Am 2019 Feb;37(1):95-107

Department of Emergency Medicine, Loma Linda University School of Medicine, 11234 Anderson Street MC A-108, Loma Linda, CA 92354, USA. Electronic address:

Infection of the neck is a relatively common emergency department complaint. If not diagnosed and managed promptly, it may quickly progress to a life-threatening infection. These infections can result in true airway emergencies that may require fiberoptic or surgical airways. Read More

Korean J Neurotrauma 2018 Oct 31;14(2):155-158. Epub 2018 Oct 31.

Department of Neurosurgery, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.

Deep neck infections (DNIs) are mainly caused by dental caries, tonsillitis, and pharyngitis; however, DNIs can also occur after head and neck trauma. A 79-year-old male patient underwent a craniectomy due to an acute subdural hematoma. The patient was unconscious and continued to have a fever, but no clear cause was found. Read More

J Emerg Med 2019 Jan 1;56(1):70-73. Epub 2018 Nov 1.

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.

Background: Parapharyngeal space abscesses (PPSA) are deep-space neck infections that are associated with significant morbidity and, rarely, mortality if not promptly diagnosed and treated. The diagnosis is often difficult, as the clinical presentation can mimic peritonsillar abscesses (PTA). Transoral point-of-care ultrasound (POCUS) may be a useful tool to help distinguish PTAs from other deep-space infections such as PPSAs. Read More

J Clin Exp Dent 2018 Oct 1;10(10):e1049-e1053. Epub 2018 Oct 1.

DDS, DMSc, Professor and Chair, Department of Oral and Maxillofacial Surgery, Nara Medical University, Nara, Japan.

Hyperimmunoglobulin E syndrome is a primary immunodeficiency state that is characterized by eczema, recurrent skin and lung infections, and markedly increased levels of IgE. Odontogenic infection can spread to vital and deep structures in such immunocompromised patients. We report a case of a 19-year-old man with hyperimmunoglobulin E syndrome presenting deep neck space infection that had spread from periapical periodontitis of the lower molars. Read More

J Clin Med 2018 Oct 25;7(11). Epub 2018 Oct 25.

Department of Otolaryngology, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.

Objective: To investigate the risk of deep neck infection (DNI) in patients with type 1 diabetes mellitus (T1DM).

Methods: The database of the Registry for Catastrophic Illness Patients, affiliated to the Taiwan National Health Insurance Research Database, was used to conduct a retrospective cohort study. In total, 5741 patients with T1DM and 22,964 matched patients without diabetes mellitus (DM) were enrolled between 2000 and 2010. Read More

Case Rep Otolaryngol 2018 27;2018:7307290. Epub 2018 Sep 27.

Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Deep neck abscess is a life-threatening infection that causes laryngeal edema and upper airway occlusion. The predominant bacterial species involved in this disorder is group A streptococcus. Group G streptococcus (GGS) constitutes the normal commensal flora of the human upper airway. Read More

J Emerg Med 2018 Dec 17;55(6):841-844. Epub 2018 Oct 17.

University of California San Diego, San Diego, California.

Background: In the winter months, one often sees a large increase in the volume of patients presenting to emergency departments with acute pharyngitis. While most cases of acute pharyngitis are benign, a rare minority can be life threatening.

Case Report: We report a case of epiglottis with a concomitant peritonsillar abscess (PTA) in an adult who presented to the emergency department with a sore throat. Read More

Med Clin North Am 2018 Nov 20;102(6):1109-1120. Epub 2018 Sep 20.

Otolaryngology-Head and Neck Surgery, University of California, San Francisco, 2233 Post Street, 3rd floor, San Francisco, CA 94115, USA.

Infections of the head and neck are common and appropriately managed by primary care providers in most cases. However, some infections are associated with significant morbidity and require urgent recognition and management by specialty services. These include deep neck space infections originating in the oral cavity, pharynx, and salivary glands, as well as complicated otologic and sinonasal infection. Read More

Acta Biomed 2018 Oct 8;89(3):406-407. Epub 2018 Oct 8.

Kars Harakani State Hospital.

Deep neck infection is life-threatening and mortal condition that requires immediate treatment. This infection is generally polymicrobial and frequently seen after upper respiratory infections, poor dental hygiene, trauma and surgery to the head and neck region. The symptoms of deep neck infections are swelling, dysphagia, pain, trismus, dysphonia and otalgia. Read More

J Arthroplasty 2019 Jan 21;34(1):88-92. Epub 2018 Sep 21.

Duke University Hospital, NC.

Background: Conversion total hip arthroplasties (THAs) from prior free vascularized fibular grafting (FVFG) are infrequently reported in the literature. We characterized the perioperative outcomes of patients undergoing conversion THA and compared them with those of a matched cohort of patients undergoing primary THA for osteonecrosis of the femoral head and neck (ONFHN).

Methods: The institutional database was queried for patients with FVFG requiring conversion to THA. Read More

J Clin Neurosci 2019 Jan 9;59:218-223. Epub 2018 Oct 9.

Department of Neurological Surgery, Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, NJ, USA; Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA. Electronic address:

Surgical resection of meningiomas has been associated with high rates of venous thromboembolic events (VTE) as compared with all other intracranial tumors. There is a paucity of data regarding the clinical complications and comorbidities associated with this cohort yet the underlying pathophysiological mechanism for this tumor-specific finding remains unclear. Our goal was to determine the various impacts of VTE on meningioma surgery in a large cohort of inpatient admissions. Read More

Liver Int 2018 Oct 9. Epub 2018 Oct 9.

Transplantation and Liver Surgery Clinic, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background & Aims: Chronic liver disease is a major health concern worldwide and the identification of novel modifiable risk factors may benefit subjects at risk. Few studies have analyzed periodontitis as a risk factor for liver complications. We studied whether periodontitis is associated with incident severe liver disease. Read More

Laryngoscope 2018 Oct 3. Epub 2018 Oct 3.

Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, U.S.A.

Objectives/hypothesis: New advances in osseous microvascular mandibular rigid fixation are being employed at many institutions. These include standardized prebent/preformed reconstruction plates as well as computer-aided design/computer-aided manufacturing (CAD/CAM) custom plates that are patient specific. Our goal was to assess and compare the outcomes of both of these new technologies when utilized for mandibular microvascular reconstruction. Read More

JSLS 2018 Jul-Sep;22(3)

Department of Anatomy, Faculty of Medicine and Surgery, Biomedical Sciences, University of Malta, Msida, Malta.

Background And Objectives: Thyroid disease largely affects young females, but the incidence is also increasing among males. In an effort to avoid the scarring of the neck that is synonymous with conventional thyroidectomy, endoscopic techniques have been developed over the years. The transoral endoscopic approach is the latest of these innovations that promises a scarless surgical outcome. Read More

Case Rep Infect Dis 2018 9;2018:7638639. Epub 2018 Sep 9.

Division of Infectious Diseases, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L457, Portland, Oregon 97239, USA.

Gram-negative vertebral osteomyelitis infections are increasing due to rising intravenous drug use but overall remain uncommon. Here, we present a case of cervical osteomyelitis in an intravenous drug user. vertebral osteomyelitis has been infrequently described in the literature thus far with varied antibiotic treatment regimens. Read More

JAMA Otolaryngol Head Neck Surg 2018 Nov;144(11):1044-1051

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark.

Importance: Understanding the preoperative, intraoperative, and postoperative risk factors of reoperation is the optimal way to approach decreasing its incidence.

Objective: To identify risk factors of unplanned reoperation following major operations of the head and neck.

Design, Setting, And Participants: This retrospective cohort study queried the American College of Surgeons National Surgical Quality Improvement Program database and identified 2475 cases of major operations of the head and neck performed between 2005 and 2014. Read More

Int J Pediatr Otorhinolaryngol 2018 Nov 5;114:143-146. Epub 2018 Sep 5.

Michigan Medicine, Department of Otolaryngology, Head & Neck Surgery, Ann Arbor, MI, United States.

Objective: To determine the incidence of intratonsillar abscess (ITA) patients within the population of patients diagnosed with peritonsillar abscess (PTA) and to further characterize the differences in symptomatology and successful treatment strategies between the two groups.

Methods: This study is a retrospective chart review of patients diagnosed with PTA or ITA at our institution from 2000 to 2017. Descriptive and inferential statistics are reported, including univariate and multivariate analyses. Read More

Clin Otolaryngol 2019 Jan 25;44(1):7-13. Epub 2018 Oct 25.

Department of Otolaryngology - Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, UK.

Aim: (a) To report national trends for tonsillectomy, tonsillitis, peritonsillar abscess and deep neck space infection in secondary care. (b) To report national trends in sore throat consultations in primary care. (c) To report national trends in antibiotic prescribing in both primary and secondary care between 2011 and 2015. Read More

Int J Pediatr Otorhinolaryngol 2018 Oct 26;113:134-139. Epub 2018 Jul 26.

Caruso Department of Otolaryngology, Head and Neck Surgery Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Division of Otolaryngology, Head and Neck Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA. Electronic address:

Objective: To assess geographical sociodemographic differences in neck abscesses that require surgical drainage in Los Angeles.

Study Design: retrospective review.

Methods: We reviewed the medical records of 119 consecutive pediatric patients at Children's Hospital Los Angeles (CHLA) from 2014 to 2017 with a diagnosis of a neck abscess requiring incision and drainage. Read More

J Laryngol Otol 2018 Sep 28;132(9):775-779. Epub 2018 Aug 28.

Department of Otolaryngology - Head and Neck Surgery,Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University in the Negev,Beer-Sheva,Israel.

Objective: Necrotising otitis externa is a severe inflammatory process affecting soft tissue and bone, mostly in diabetic patients. Diabetic patients are also at risk of diabetic foot osteomyelitis, another inflammatory condition involving soft tissue and bone. This review aimed to describe the similarities and differences of these entities in an attempt to further advance the management of necrotising otitis externa. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Aug;53(8):610-614

Department of General Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.

To explore the diagnosis and treatment of head and neck Castleman's disease (CD), and to improve the understanding of the disease. The clinical data of 41 patients with head and neck CD treated from January 2007 to July 2017 in the First Affiliated Hospital of Zhengzhou University were analyzed retrospectively. The patients were divided into two groups: localized CD (LCD, =27) and multicentric CD (MCD, =14). Read More

Am J Emerg Med 2018 Nov 8;36(11):2132.e5-2132.e7. Epub 2018 Aug 8.

Nevsehir State Hospital, Emergency Department, Nevsehir, Turkey. Electronic address:

Laryngopyocele is a rare diagnosis that can cause life-threating conditions such as airway obstruction and even death. Emergency ultrasound (POCUS) can be very helpful during the diagnosis and monitoring of the illness because it is both easy to apply and repeatable. A deep neck infection was diagnosed as laryngopyocele by POCUS in the emergency department; this is the first case in the literature. Read More

Int J Pediatr Otorhinolaryngol 2018 Sep 19;112:80-81. Epub 2018 Jun 19.

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, United States.

The disease of parapharyngeal abscess is well known to the otolaryngologist and is commonly managed via transoral, transcervical, or combined incision and drainage. We report a novel approach to an abscess that was drained through the external auditory canal (EAC). An otherwise healthy 2-year-old female presented with a 4-day history of fevers, decreased oral intake, neck stiffness, and voice changes. Read More

Ann Otol Rhinol Laryngol 2018 Oct 21;127(10):698-702. Epub 2018 Jul 21.

2 Department of Otolaryngology, SUNY Downstate Medical Center, Brooklyn, NY.

Objectives: The authors report a small case series of an unusual ingested foreign body, wire brush bristles, whose small size can present a challenge for endoscopic removal. The authors describe transnasal endoscopic removal and provide a literature review.

Methods: From 2011 to 2017, 8 patients presented to an academic tertiary medical center with ingestion of wire brush bristles. Read More

Clin Exp Otorhinolaryngol 2018 Dec 20;11(4):293-300. Epub 2018 Jul 20.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objectives: The current study aims to determine the correlation between nutritional status upon presentation and disease severity, as well as treatment and survival outcomes.

Methods: Patients who were diagnosed with deep neck infection, underwent at least one surgical drainage/debridement, and had more than 1 week of hospitalization at a tertiary medical center from 2007 to 2015 were retrospectively included. Thereafter, initial serum albumin, C-reactive protein (CRP), and body mass index (BMI) were reviewed. Read More

J Bone Jt Infect 2018 11;3(3):123-129. Epub 2018 Jun 11.

Consultant Trauma and Orthopaedic Surgeon, Northumbria Specialist Emergency Healthcare Centre, Northumbrian Road, Cramlington, NE23 6NZ, United Kingdom.

The incidence of fractured neck of femur (FNOF) is increasing yearly. Many of these patients undergo hip hemiarthroplasty. High dose dual-antibiotic cement (HDDAC) has been shown to reduce rates of deep surgical site infection (SSI) when compared to the current standard low dose single-antibiotic cement (LDSAC) in a quasi-randomised controlled trial. Read More

J Med Case Rep 2018 Jul 7;12(1):195. Epub 2018 Jul 7.

Department of Surgery, Banso Baptist Hospital, P.O Box 9, Nso-Kumbo, Northwestern Region, Cameroon.

Background: We report two cases of innocuous dentoalveolar infections which rapidly progressed to deep neck abscesses complicated by descending mediastinitis in a resource-constrained rural mission hospital in the Cameroon.

Case Presentation: The clinical presentations of a 35-year-old man and a 32-year-old woman both of Fulani origin in the Northern region of Cameroon were similar with submandibular fluctuant and tender swelling and differential warmth to palpation. The patients had tachycardia, high grade pyrexia, and normal blood pressure. Read More

Proteomics Clin Appl 2018 Nov 18;12(6):e1800007. Epub 2018 Jul 18.

Klinik und Poliklinik für Hautkrankheiten, University Medicine Greifswald, 17475, Greifswald, Germany.

Purpose: Increasing incidence of onychomycosis and tinea pedis in humans of industrialized countries together with deep tissue infections are a therapeutic challenge in clinical mycology. For a better understanding of the pathology and immunology of infection, the authors analyze the exoproteomes of three reference strains of the most common clinical dermatophyte species (Trichophyton rubrum, Trichophyton interdigitale, Arthroderma benhamiae) and of Trichophyton strains isolated from affected patients.

Experimental Design: Extracellular proteins of those in vitro grown strains are separated via 2D High Performance Electrophoresis and identified by mass spectrometry to find proteins with provoked host immune reactivity. Read More

J Cancer 2018 30;9(11):1943-1950. Epub 2018 Apr 30.

Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P.R. China.

: Little knowledge about long non-coding RNAs(lncRNAs) in nasopharyngeal carcinoma (NPC) has been acquired. : Next-generation sequencing was applied in 7 cases of NPC tissues and 7 cases of normal tissues in nasopharynx. PLEX, CNCI and CPAT soft-wares were used to predict novel lncRNAs. Read More