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J Tissue Viability 2022 May 16. Epub 2022 May 16.

Department of Nursing, Ankara Yildirim Beyazit University Faculty of Health Sciences, Ankara, Turkey.

Aim: This study investigated the effect of care under the guidance of a pressure ulcer prevention care bundle on pressure ulcer incidence rates and on nursing workload costs.

Design, Setting, And Participants: This prospective pre-post interventional study was conducted in an anesthesia and reanimation intensive care unit. The sample consisted of 16 nurses and 84 patients. Read More

Cir Esp (Engl Ed) 2022 May 15. Epub 2022 May 15.

Unidad de Cirugía de Pared Abdominal, Hospital Universitari i Politècnic La Fe, Universidad de Valencia, Valencia, Spain.

Negative pressure wound therapy (NPWT) is widely known in surgical practice. The initial indications for NPWT were chronic wounds, especially diabetic foot, vascular and decubitus ulcers, and infected traumatic wounds. Nowadays, the use has been widely increased. Read More

Int Wound J 2022 May 18. Epub 2022 May 18.

Gynecology of Integrated Traditional Chinese and Western Medicine, Beijing Xicheng Guangwai Hospital, Beijing, China.

We performed a meta-analysis to evaluate the influence of Chinese herbal medicines on cancer-related pressure ulcer wounds, fatigue, constipation, and anorexia. A systematic literature search up to March 2022 was done and 25 studies included 1777 subjects with cancer-related symptoms at the start of the study; 953 of them were provided with Chinese herbal medicines and 824 were control. They were reporting relationships about the influence of Chinese herbal medicines on cancer-related pressure ulcer wounds, fatigue, constipation, and anorexia. Read More

Nutrition 2022 Feb 24;99-100:111638. Epub 2022 Feb 24.

Department of Critical Care Medicine, Seoul National University Hospital, Seoul, South Korea; Departments of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea.

Objectives: Because most patients who develop pressure ulcer (PU) are malnourished, additional nutritional support is important for PU improvement. The aim of this study was to investigate the potential benefit of a simple nutritional support protocol in PU improvement.

Methods: This study was a comparative before-and-after study, prospectively performed from May to December 2020. Read More

J Wound Care 2022 May;31(Sup5):S3-S4

University of Pittsburgh Medical Center; Director of Blair Medical Associates, UPMC Wound Clinic, Altoona, PA, US.

J Wound Care 2022 May;31(Sup5):S6-S12

Division of Plastic and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, US.

Objective: Pressure ulcers (PUs) are hard-to-heal, open wounds that affect millions of adults worldwide. Patients experience physical, mental, social and financial impairment. On average, <50% of stage 3 and 4 PUs heal by the sixth month. Read More

Int J Environ Res Public Health 2022 Apr 26;19(9). Epub 2022 Apr 26.

Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, 701 03 Ostrava, Czech Republic.

Background: Adverse events are indicators of patient safety and quality of care. Adverse events clearly have negative impacts on healthcare system costs. Organizational and unit characteristics are not very often studied in relation to adverse events. Read More

Hautarzt 2022 May 12. Epub 2022 May 12.

Klinik für Gefäßmedizin, HELIOS Klinikum Krefeld, Krefeld, Deutschland.

Venous ulcus cruris is usually a chronic disease and an extreme burden for patients and their families. An analysis based on a random statutory health insurance sample of the AOK Hessen/KV Hessen estimated the number of affected people to be 400,000 in Germany. A venous ulcus cruris is always caused by an underlying chronic venous insufficiency (CVI). Read More

Int Wound J 2022 May 11. Epub 2022 May 11.

Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.

People with spinal cord injury (SCI) are at high risk of developing a pressure injury. It is unclear why some people with SCI develop pressure injury while others with similar predisposing risk factors do not during acute hospitalisation. This may hinder healthcare utilisation to prevent pressure injuries. Read More

Health Sci Rep 2022 May 5;5(3):e620. Epub 2022 May 5.

School of Nursing The Hashemite University Zarqa Jordan.

Background: Medical device-related pressure ulcers are increasingly common in critical care units. These ulcers can be complicated due to the necessity of the device for diagnosis or treatment.

Purpose: To determine the prevalence of and risk for medical device-related pressure ulcers in critical care units in Jordan in addition to identifying the preventive measures for those ulcers as well as identifying the most frequently used medical devices that cause ulcers and to assess the relationships between prevention measures and developing ulcers. Read More

JAMA Netw Open 2022 May 2;5(5):e2211321. Epub 2022 May 2.

Division of Infectious Diseases, Department of Medicine and Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Importance: Traditional approaches to practice guidelines frequently result in dissociation between strength of recommendation and quality of evidence.

Objective: To construct a clinical guideline for pyogenic osteomyelitis management, with a new standard of evidence to resolve the gap between strength of recommendation and quality of evidence, through the use of a novel open access approach utilizing social media tools.

Evidence Review: This consensus statement and systematic review study used a novel approach from the WikiGuidelines Group, an open access collaborative research project, to construct clinical guidelines for pyogenic osteomyelitis. Read More

J Eur Acad Dermatol Venereol 2022 May 10. Epub 2022 May 10.

Dermatology, National Skin Centre, Singapore.

Background: Populations around the world are rapidly ageing. The profile of skin diseases in the elderly is likely to present unique demands on the healthcare system.

Objectives: To provide current data on the burden of skin diseases in Singaporean patients and identify differences in the pattern of skin diseases between elderly patients and the rest of the population. Read More

Diabetes Metab Syndr Obes 2022 3;15:1347-1355. Epub 2022 May 3.

Department of Endocrinology, Air Force Medical Center, Beijing, 100142, People's Republic of China.

Background: The fat-soluble molecule vitamin D has attracted much attention since its pleiotropism was discovered. Its effectiveness can be attributed to the presence of vitamin D receptors in most of the body's tissues. Based on the classical role of vitamin D in regulating calcium and phosphorus metabolism and maintaining bone health, the role of vitamin D in immunity, type 2 diabetes mellitus (T2DM), tumor and cardiovascular diseases has been further discovered. Read More

Cureus 2022 Apr 6;14(4):e23870. Epub 2022 Apr 6.

Biochemistry, All India Institute of Medical Sciences, Bibinagar, Hyderabad, IND.

Introduction Isn't it a boon that all living organisms possess the ability to heal their injuries? The wound healing is faster when the normal physiology of the wound healing is maintained. Our understanding of wound healing has undergone dramatic changes in the recent past. Almost all materials and methods available on earth have been used and tested to facilitate the process of wound healing. Read More

Case Rep Gastroenterol 2022 Jan-Apr;16(1):223-228. Epub 2022 Mar 31.

Department of Gastroenterology, Clinic for Visceral Surgery and Medicine, Bern University Hospital, Bern, Switzerland.

Duodenal perforation is rare and associated with a high mortality. Therapeutic strategies to address duodenal perforation include conservative, surgical, and endoscopic measures. Surgery remains the gold standard. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2022 Apr;42(4):604-609

Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Objective: To investigate the clinical characteristics of lower extremity arterial disease (LEAD) and its risk factors in patients with diabetic foot ulcer (DFU).

Methods: We retrospectively collected the clinical and follow-up data of 650 patients with DFU treated in the Department of Endocrinology and Metabolism of Nanfang Hospital between January, 2017 and December, 2019. We compared the data between patients who had LEAD and those without LEAD and used a multivariate logistic regression model to analyze the risk factors of LEAD in DFU patients. Read More

J Formos Med Assoc 2022 May 4. Epub 2022 May 4.

Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan. Electronic address:

Background/purpose: Pressure ulcers are a common problem in hospital care and long-term care. Pressure ulcers are caused by prolonged compression of soft tissues, which can cause local tissue damage and even lead to serious infections. This study uses a deep learning algorithm to construct a system that diagnoses pressure ulcers and assists in making treatment decisions, thus providing additional reference for first-line caregivers. Read More

J Wound Ostomy Continence Nurs 2022 May-Jun 01;49(3):211-219

Laura E. Edsberg, PhD, Center for Wound Healing Research and Natural & Health Sciences Research Center, Daemen University, Amherst, New York.

Purpose: The purpose of this study was to evaluate the implementation of pressure injury (PI) prevention strategies in adult acute care settings in the United States using the data from the 2018/2019 International Pressure Ulcer Prevalence (IPUP) Survey.

Design: Observational, cohort study with cross-sectional data collection and retrospective data analysis.

Subjects And Setting: The sample comprised 296,014 patients hospitalized in 1801 acute care facilities in the United States that participated in the 2018 and/or 2019 IPUP Survey. Read More

J Wound Ostomy Continence Nurs 2022 May-Jun 01;49(3):207-209

J Foot Ankle Res 2022 May 5;15(1):31. Epub 2022 May 5.

School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.

Background: Pressure offloading treatment is critical for healing diabetes-related foot ulcers (DFU). Yet the 2011 Australian DFU guidelines regarding offloading treatment are outdated. A national expert panel aimed to develop a new Australian guideline on offloading treatment for people with DFU by adapting international guidelines that have been assessed as suitable to adapt to the Australian context. Read More

Int J Nurs Sci 2022 Apr 18;9(2):169-178. Epub 2022 Mar 18.

Critical Care Department, San Cecilio University Hospital, Granada, Spain.

Objective: To translate an intensive care-specific pressure injury risk assessment tool (the COMHON Index) from English into Chinese Mandarin.

Methods: A four-step approach to instrument translation was utilised: 1) English-Mandarin forward-translation by three independent bilinguists; 2) Mandarin-English back-translation by two other independent bilinguists; 3) comparison of forward and back-translations, identification of discrepancies, with required amendments returned to step one; and 4) piloting of the translated instrument. The pilot study was undertaken in a Chinese surgical intensive care unit with a convenience sample of 20 nurses. Read More

Phlebology 2022 May 3:2683555221088101. Epub 2022 May 3.

Dermatology, Phlebology and Fluid Mechanics Research Laboratory, St Vincent's Centre for Applied Medical Research, Darlinghurst NSW Australia.

Tissue necrosis is a significant but uncommon complication of sclerotherapy. The pathogenic mechanisms of this often-debilitating complication have been poorly described in the literature. To elucidate the pathological mechanisms, we propose a morphological approach to classify sclerotherapy-induced skin necrosis into two categories of round and stellate (star-like) necrosis. Read More

Eur Rev Med Pharmacol Sci 2022 Apr;26(8):2960-2969

Spinal Surgery Department, Viet Duc University Hospital, Hanoi, Vietnam.

Objective: This report aimed to characterize clinical and imaging characteristics and outcomes of the patients with lower cervical spine injury combined with spinal cord paralysis who underwent posterior cervical spine surgery.

Patients And Methods: Between January 2019 and December 2020, a retrospective evaluation of prospectively collected data at one institution was conducted. We included all patients who were diagnosed with subaxial cervical spine injuries (C3-7), had spinal cord paralysis, and underwent posterior cervical spine surgery. Read More

J Tissue Viability 2022 Apr 28. Epub 2022 Apr 28.

University Hospital Centre Zagreb, Kišpatićeva St 12, 10 000, Zagreb, Croatia. Electronic address:

Aim: The aim of the study was to determine the knowledge of nurses and nursing students about pressure injury (PI) prevention.

Materials And Methods: A cross-sectional study was used, and the sample consisted of 312 participants, of whom 198 were nursing students and 114 were nurses from the clinical hospital. The response rate for the total population was 78%. Read More

Front Surg 2022 13;9:739250. Epub 2022 Apr 13.

Department of Plastic and Burn Surgery, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China.

Background: Decubitus ulcers are common skin injuries in plastic and burn surgery departments, usually occur in patients with a long disease course and poor underlying health. Designing a reconstruction procedure with safety blood supply to a large volume soft tissue and resulting in minimal trauma is a priority for surgeons.

Methods: The free-style perforators on the potential donor sites surrounding the ulcers were detected by Doppler, and the area of the ulcer was divided into several sections based on the location of pre-design perforator flaps. Read More

J Tissue Viability 2022 Apr 18. Epub 2022 Apr 18.

Department of Dermatology and Advanced Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, 474-8511, Japan. Electronic address:

We report the case of a pressure ulcer that developed consequent to the discontinuation of levodopa (L-3,4-dihydroxyphenylalanine) administration. The 86-year-old female patient had a 5-year history of Parkinson's disease treated with levodopa. She developed a sacral pressure ulcer due to unanticipated immobilization induced by the discontinuation of levodopa. Read More

JMIR Med Inform 2022 May 12;10(5):e38308. Epub 2022 May 12.

Research Group of Humanities and Qualitative Research in Health Science, Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, Alcorcón, Spain.

Background: The COVID-19 pandemic has changed the usual working of many hospitalization units (or wards). Few studies have used electronic nursing clinical notes (ENCN) and their unstructured text to identify alterations in patients' feelings and therapeutic procedures of interest.

Objective: This study aimed to analyze positive or negative sentiments through inspection of the free text of the ENCN, compare sentiments of ENCN with or without hospitalized patients with COVID-19, carry out temporal analysis of the sentiments of the patients during the start of the first wave of the COVID-19 pandemic, and identify the topics in ENCN. Read More

J Spinal Cord Med 2022 Apr 29:1-10. Epub 2022 Apr 29.

Department of Clinical Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Objective: This study aimed to investigate the improvements of functional independence following inpatient rehabilitation and compare those improvements between different levels and severities of Spinal Cord Injury (SCI). Prognostic factors affecting the patient's outcomes were also studied.

Settings: Rofeideh Rehabilitation Hospital. Read More

Aust Crit Care 2022 Apr 25. Epub 2022 Apr 25.

Chonnam National University College of Nursing, 160 Baekseoro, Donggu, Gwangju, 61469, Republic of Korea. Electronic address:

Background: Pressure injuries (PIs) are a well-known complication of critically ill patients admitted to the intensive care unit with targeted temperature management (TTM) after cardiac arrest (CA). However, little is known about the factors that impact the occurrence of PIs among these patients.

Objectives: This study aimed to examine factors related to the occurrence of PIs among patients after CA treated with TTM. Read More

J Am Podiatr Med Assoc 2022 Apr 27;112(2). Epub 2022 Apr 27.

†Haycock Foot and Ankle Center, Lima, OH.

Heel decubitus ulcerations are relatively common occurrences that can be limb threatening. There are many options to treat these ulcerations, ranging from conservative wound care to serial debridement with flap reconstruction. However, not all patients are good candidates for major reconstructive surgery. Read More