18,680 results match your criteria Decubitus Ulcers


A novel debridement device for the treatment of hard-to-heal wounds: a prospective trial.

J Wound Care 2021 May;30(Sup5):S32-S36

The SerenaGroup Research Foundation, Cambridge, MA, US.

Objective: Debridement, the removal of nonviable tissue, forms the foundation of wound care practice. Clinicians have a variety of debridement methods at their disposal: sharp, biologic, enzymatic, autolytic and mechanical. The choice of debridement technique depends on the patient care setting, ulcer type and the clinician's experience, training, comfort level and licensure. Read More

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A Comparison of the Braden Q and the Braden QD Scale to Assess Pediatric Risk for Pressure Injuries During Noninvasive Ventilation.

Respir Care 2021 May 11. Epub 2021 May 11.

Rady Children's Hospital and Health Center-San Diego, San Diego, CA.

Background: Noninvasive ventilation (NIV) masks are implicated in 59% of respiratory device-related pressure injuries in hospitalized children. Historically, the Braden Q scale was not adequate in identifying risk for pressure injury associated with devices and, therefore, was modified to the Braden QD scale. The purpose of this study was to evaluate whether the Braden QD scoring tool is better able to identify pediatric patients receiving NIV who are at risk for the development of pressure injury as compared to the previously used Braden Q scale. Read More

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Alternating pressure (active) air surfaces for preventing pressure ulcers.

Cochrane Database Syst Rev 2021 May 10;5:CD013620. Epub 2021 May 10.

Nursing Research Institute, St Vincent's Health Australia Sydney, St Vincent's Hospital Melbourne & Australian Catholic University, Fitzroy, Melbourne, Australia.

Background: Pressure ulcers (also known as pressure injuries, pressure sores, decubitus ulcers and bed sores) are localised injuries to the skin or underlying soft tissue, or both, caused by unrelieved pressure, shear or friction. Alternating pressure (active) air surfaces are widely used with the aim of preventing pressure ulcers.

Objectives: To assess the effects of alternating pressure (active) air surfaces (beds, mattresses or overlays) compared with any support surface on the incidence of pressure ulcers in any population in any setting. Read More

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Beds, overlays and mattresses for treating pressure ulcers.

Cochrane Database Syst Rev 2021 May 10;5:CD013624. Epub 2021 May 10.

Nursing Research Institute, St Vincent's Health Australia Sydney, St Vincent's Hospital Melbourne & Australian Catholic University, Fitzroy, Melbourne, Australia.

Background: Pressure ulcers (also known as pressure injuries, pressure sores, decubitus ulcers and bed sores) are localised injuries to the skin or underlying soft tissue, or both, caused by unrelieved pressure, shear or friction. Beds, overlays or mattresses are widely used with the aim of treating pressure ulcers.

Objectives: To assess the effects of beds, overlays and mattresses on pressure ulcer healing in people with pressure ulcers of any stage, in any setting. Read More

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Trophic ulcer over lateral malleolus successfully treated using a bangle for off-loading pressure.

Indian J Dermatol Venereol Leprol 2021 Apr 23:1-2. Epub 2021 Apr 23.

Department of Dermatology and Venereology, AIIMS, Bhubaneswar, Odisha, India.

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The combined impact of ankle-brachial index and transcutaneous oxygen pressure on mortality in patients with type 2 diabetes and foot ulcers.

Acta Diabetol 2021 May 8. Epub 2021 May 8.

Clinical Sciences in Lund, Lund University, Lund, Sweden.

Aims: A diabetic foot ulcer (DFU) is associated with increased cardiovascular risk and mortality, independently of ulcer etiology (ischemic, neuro-ischemic or neuropathic). Ankle-brachial index (ABI) is the most commonly used test when diagnosing peripheral macrovascular disease and is a well-known marker for increased cardiovascular risk. Transcutaneous oxygen pressure (TcPO) is considered to better evaluate microvascular function and has in previous studies shown correlations with both wound healing and survival. Read More

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Surgical debridement, maggot therapy, negative pressure wound therapy, and silver foam dressing revive hope for patients with diabetic foot ulcer: A case report.

Int J Surg Case Rep 2021 Apr 29;82:105931. Epub 2021 Apr 29.

Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Urmia University of Medical Sciences, Urmia, Iran. Electronic address:

Introduction And Importance: Diabetic foot ulcers (DFUs), as one of the most debilitating complications of diabetes, can lead to amputation. Treatment and management of d DFUs are among the most critical challenges for the patients and their families.

Case Presentation: The present case report is of a 63-year-old man with a 5-year history of uncontrolled type 2 diabetes who has had DFU for the past three years on three sites of the left external ankle in the form of two deep circular ulcers with sizes of 6 × 4 cm and 6 × 8 cm, the sole as a superficial ulcer with a size of 6 × 3 cm, and the left heel as a deep skin groove. Read More

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Derivation and validation of actionable quality indicators targeting reductions in complications for injury admissions.

Eur J Trauma Emerg Surg 2021 May 7. Epub 2021 May 7.

Axe Santé des Populations et Pratiques Optimales en Santé (Population Health and Optimal Health Practices Research Unit), Traumatologie-Urgence-Soins Intensifs (Trauma-Emergency-Critical Care Medicine), Centre de Recherche du CHU de Québec (Hôpital de l'Enfant-Jésus), Université Laval, Québec, QC, Canada.

Purpose: Approximately, one out of five patients hospitalized following injury will develop at least one hospital complication, more than three times that observed for general admissions. We currently lack actionable Quality Indicators (QI) targeting specific complications in this population. We aimed to derive and validate QI targeting hospital complications for injury admissions and develop algorithms to identify patient charts to review. Read More

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Using Manchester Scale classification of Hallux Valgus as a valuable tool in determining appropriate risk categorization during initial diabetic foot screening in primary health care settings.

Foot (Edinb) 2021 Apr 19;47:101810. Epub 2021 Apr 19.

Dufferin Area Family Health Team (DAFHT), 140 Rolling Hills Dr., Upper Level, Orangeville Ontario, L9W 4X8, Canada. Electronic address:

Limitations have been identified in the current state of primary care practises with regards to identifying and correctly categorizing foot deformity and its associated risk of developing foot ulcers in patients with diabetes. This study aims to bridge these gaps through the implementation of additional categorization tools to be made available for primary care professionals. This study thus analysed the relationship between foot pressure distribution and amount in patients with diabetes with Hallux Valgus foot deformity, and its different stages, in order to better understand the clinical applications of the Manchester Scale. Read More

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Combination treatment of dendrosomal nanocurcumin and low-level laser therapy develops proliferation and migration of mouse embryonic fibroblasts and alter TGF-β, VEGF, TNF-α and IL-6 expressions involved in wound healing process.

PLoS One 2021 6;16(5):e0247098. Epub 2021 May 6.

Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.

Introduction: Pressure ulcer (PU) is known as the third most costly disorder usually caused by prolonged pressure and stagnation in various parts of the body. Although several therapeutic approaches are employing, obstacles in appropriate healing for skin lesions still exist which necessitates new practical alternative or adjunctive treatments. Low level laser therapy (LLLT) as one of the mentioned new strategies have gained attention. Read More

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Learning During Crisis: The Impact of COVID-19 on Hospital-Acquired Pressure Injury Incidence.

J Healthc Qual 2021 May-Jun 01;43(3):137-144

Abstract: The impact of COVID-19, on the health and safety of patients, staff, and healthcare organizations, has yet to be fully uncovered. Patient adverse events, such as hospital-acquired pressure injuries (HAPIs), have been problematic for decades. The introduction of a pandemic to an environment that is potentially at-risk for adverse events may result in unintended patient safety and quality concerns. Read More

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Conceptual Framework for Incontinence-Associated Dermatitis Based on Scoping Review and Expert Consensus Process.

J Wound Ostomy Continence Nurs 2021 May-Jun 01;48(3):239-250

Manuel Rodríguez-Palma, PhD, MSN, RN, Nursing Home "José Matía Calvo," Cádiz, Spain; and Executive Member of Spanish Pressure Ulcer Advisory Panel.

Incontinence-associated dermatitis (IAD) has been studied over the last decades, but gaps in the knowledge related to its identification, etiological agents, and risk factors remain. We carried out a scoping review about IAD that included systematic reviews, experimental, and observational studies about IAD and its potential risk factors. We retrieved 24 articles that described 100 potential risk factors and which were synthesized by the authors and proposed to a panel of experts. Read More

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Development of a model to predict closure of chronic wounds in Germany: Claims data analysis.

Int Wound J 2021 May 5. Epub 2021 May 5.

German Center for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

Patients with chronic leg ulcer, pressure ulcer, or diabetic foot ulcer suffer from significant disease burden. With a view to improving healthcare provision sustainably, a predictive model of time to closure (time-to-event analysis) based on claims data was developed. To identify potential predictors of wound closure, clinical information absent from statutory health insurance (SHI) data was modelled. Read More

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Knowledge and Attitude of Community Nurses on Pressure Injury Prevention: A Cross-sectional Study in an Indonesian City.

Int Wound J 2021 May 4. Epub 2021 May 4.

Department of Health Services Research, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.

The objectives of this study were to examine the knowledge and attitude of Indonesian community nurses regarding Pressure Injury (PI) prevention. A cross-sectional design was used and included the community nurses permanently working in the Public Health Center (Puskemas) in Bandung, West Java Indonesia. Knowledge was measured using the Pressure Ulcer Knowledge Assessment Tool (PUKAT 2. Read More

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Effects of loading and prophylactic dressings on the sacral and heel skin: An exploratory cross-over trial.

Int Wound J 2021 May 3. Epub 2021 May 3.

Charite Center for Health and Human Sciences, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Pressure ulcers/injuries are caused by sustained loading and deformation of skin and underlying soft tissues. Prophylactic dressings are recommended as an adjunct to other preventive measures such as repositioning and offloading. The aim of this study was to investigate the effects of prophylactic soft silicone multi-layered foam dressings on the skin structure and function of the two most common pressure areas, sacrum and heel, with and without loading. Read More

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Pressure Ulcer Injury in Unstructured Clinical Notes: Detection and Interpretation.

AMIA Annu Symp Proc 2020 25;2020:1160-1169. Epub 2021 Jan 25.

Department of Computer Science, Emory University, Atlanta, GA, US.

Hospital-acquired pressure ulcer injury (PUI) is a primary nursing quality metric, reflecting the caliber of nursing care within a hospital. Prior studies have used the Braden scale and structured data from the electronic health records to detect/predict PUI while the informative unstructured clinical notes have not been used. We propose automated PUI detection using a novel negation-detection algorithm applied to unstructured clinical notes. Read More

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January 2021

The relationships between paediatric nurses' social support, job satisfaction and patient adverse events.

Nurs Open 2021 May 2. Epub 2021 May 2.

Institute of Nursing Sciences, Basic Health Sciences and Health Visiting, Faculty of Health Sciences, University of Pécs, Pécs, Hungary.

Aims: To explore the relationships of family, co-worker and manager support with paediatric nurses' satisfaction and their perception of adverse events. Furthermore, this study aimed to assess the job satisfaction, social support and the perceived patient adverse events.

Design: This study used a cross-sectional correlational design. Read More

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Intestinal Dysbiosis Disguised as a Rectal Fistula Treated With Autologous Fecal Microbiota Transplantation.

Cureus 2021 Mar 25;13(3):e14115. Epub 2021 Mar 25.

Gastroenterology, Grand Strand Medical Center, Myrtle Beach, USA.

Fecal microbiota transplantation (FMT) has been efficacious in the treatment of intestinal dysbiosis, derangement of the native intestinal microflora, and the indications for autologous FMT are growing. A 69-year-old Caucasian man with a past medical history of paraplegia secondary to motor vehicle accident and sigmoid-end colostomy presented to his gastroenterologist with the complaint of rectal discharge. A complicated medical course pre-dated his presentation and included multiple decubitus ulcers requiring debridement and several courses of broad-spectrum antibiotics. Read More

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Successful Management of a Severe Sacral Pressure Injury Penetrating to the Retroperitoneum.

Wounds 2021 Mar;33(3):E24-E27

Division of Pressure Ulcer Prevention, Graduate School of Medical Sciences, Kyushu University, Japan.

Introduction: Reports of retroperitoneal infection related to a sacral pressure injury (PI) are rare, and none of the reports described the direct spread of infection through the sacrum to the retroperitoneum. The authors present, to their knowledge, the first report of a severely infected PI that showed full-thickness sacral destruction and direct retroperitoneal penetration.

Case Report: A 63-year-old female was referred for management of a stage 4 sacral PI complicated by a retroperitoneal abscess. Read More

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Atypical Pyoderma Gangrenosum in the Setting of Venous and Arterial Insufficiency.

Int J Low Extrem Wounds 2021 Apr 29:15347346211002334. Epub 2021 Apr 29.

6684Oregon Health & Science University, Portland, OR, USA.

Ulcers of mixed etiology are diagnostically elusive and challenging to treat, especially when rare conditions are superimposed. Pyoderma gangrenosum (PG) is an autoinflammatory, ulcerative skin disease that is difficult to diagnose. Diagnostic criteria exist but there are no specific clinical tests to identify it. Read More

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Pressure Relieving Support Surfaces: a Randomised Evaluation 2 (PRESSURE 2): using photography for blinded central endpoint review.

Trials 2021 Apr 28;22(1):308. Epub 2021 Apr 28.

Clinical Trials Research Unit, University of Leeds, Leeds, UK.

Background: PRESSURE 2 is a randomised evaluation of the clinical and cost-effectiveness of two types of mattress for the prevention of pressure ulcers (PUs). The primary clinical endpoint was time to development of a category ≥2 PU. The current 'gold standard' for PU identification is expert clinical assessment. Read More

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Effectiveness and safety of Chinese medicine combined with omeprazole in the treatment of gastric ulcer: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Apr;100(17):e25744

Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, China.

Background: Gastric ulcer (GU) is a common digestive system disease, and the main clinical manifestations are nausea and epigastric pain. In recent years, due to increased life pressure, unhealthy eating habits and environment, the incidence of gastric ulcer has increased year by year. Because the disease has a long treatment cycle and is prone to relapse, if it cannot be controlled in time, it can cause the disease to prolong, affect the daily life and health of the patient, and even cause complications such as upper gastrointestinal bleeding, ulcer perforation, and pyloric obstruction. Read More

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Stem cell and tissue engineering approaches in pressure ulcer treatment.

J Spinal Cord Med 2021 Apr 27:1-10. Epub 2021 Apr 27.

Unidad de Terapia Celular y Medicina Regenerativa, Servicio de Hematología y Hemoterapia, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.

Context: Pressure ulcers or injuries, arise from ischemic damage to soft tissues induced by unrelieved pressure over a bony prominence. They are usually difficult to treat with standard medical therapy and often they recur. In the search for better treatment options, promising alternative forms of treatment are today emerging. Read More

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[Curative claw trimming for mechanical relief of sole ulcers - an ex-vivo study].

Tierarztl Prax Ausg G Grosstiere Nutztiere 2021 Apr 26;49(2):92-100. Epub 2021 Apr 26.

Veterinär-Anatomisches Institut, Veterinärmedizinische Fakultät, Universität Leipzig.

Objective: Overloading or excessive mechanical stress to the claws may damage the sensitive claw tissues and subsequently lead to sole ulcers. Corrective treatment can prevent complications of these sole ulcers. The aim of this study was to investigate the effects of a wedge-shaped relief incision from the bulb to the tip of the outer claw of the pelvic limb on the pressure distribution beneath the pertaining claw. Read More

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Association of Nursing Practice Environment on reported adverse events in private management hospitals: A cross-sectional study.

J Clin Nurs 2021 Apr 23. Epub 2021 Apr 23.

Doctorate Programme coordinator Nursing and Health, Research Group Advanced Nursing, Universitat Rovira i Virgili, Tarragona, Spain.

Aims And Objectives: To examine the relationships between nurses' perceptions of their practice environment, other working conditions and reported adverse events in two private management hospitals.

Background: Patient safety is influenced by knowledge, available resources and the context in which nursing care is provided. In this sense, it has been found that certain work environments (e. Read More

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Brief intermittent pressure off-loading on skin microclimate in healthy adults - A descriptive-correlational pilot study.

J Tissue Viability 2021 Mar 6. Epub 2021 Mar 6.

School of Nursing & Midwifery, College of Science, Health and Engineering, La Trobe University, Melbourne, Victoria, Australia.

Aim: This study examined microclimate changes to the skin as a result of pressure over a 1 h period. The results were compared to skin parameter results following brief consecutive off-loading of pressure-prone areas.

Design: A descriptive-correlational pilot study was undertaken. Read More

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Multisystem outcomes and predictors of mortality in critically ill patients with COVID-19: Demographics and disease acuity matter more than comorbidities or treatment modalities.

J Trauma Acute Care Surg 2021 05;90(5):880-890

From the Division of Trauma, Emergency Surgery and Surgical Critical Care (O.A., A.M., L.N., K.L., K.A.B., M.E.M., C.K., A.G., M.A.C., L.R.M., H.M., B.B.-K., J.P., J.F., N.S., A.M., C.P., P.F., D.K., J.L., G.C.V., H.M.A.K.), and Division of Pulmonary Critical Care (M.R.F.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Background: We sought to describe characteristics, multisystem outcomes, and predictors of mortality of the critically ill COVID-19 patients in the largest hospital in Massachusetts.

Methods: This is a prospective cohort study. All patients admitted to the intensive care unit (ICU) with reverse-transcriptase-polymerase chain reaction-confirmed severe acute respiratory syndrome coronavirus 2 infection between March 14, 2020, and April 28, 2020, were included; hospital and multisystem outcomes were evaluated. Read More

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Edible and highly biocompatible nanodots from natural plants for the treatment of stress gastric ulcers.

Nanoscale 2021 Apr 7;13(14):6809-6818. Epub 2021 Apr 7.

School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China.

The incidence rate of stress ulcers has increased in recent years, with an increase in life pressure, unavoidable trauma and other factors. The therapy of acute stress ulcers has always been an important challenge. Carbon dots (CDs) have been reported to show excellent biological activities, but research on the stress ulcer curative effect of CDs is unprecedented. Read More

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Prevalence of risk for pressure ulcers, malnutrition, poor oral health and falls - a register study among older persons receiving municipal health care in southern Sweden.

BMC Geriatr 2021 04 21;21(1):265. Epub 2021 Apr 21.

Department of Care Science, Faculty of Health and Society, Malmö University, Jan Waldenströms Gata 25, SE-20506, Malmö, Sweden.

Background: Although pressure ulcers, malnutrition, poor oral health and falls are common among older persons, causing deteriorated health status, they have not been studied altogether among older persons receiving different types of municipal health care. The aim of this study was to determine the prevalence of risk for pressure ulcers, malnutrition, poor oral health and falls among older persons aged ≥65 years receiving municipal health care in southern Sweden.

Methods: A retrospective cross-sectional study (n = 12,518 persons aged ≥65 years) using data from the national quality registry Senior Alert was conducted. Read More

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Eliminating non-healing wounds: a review.

Authors:
Damien P Kuffler

Regen Med 2021 04 20;16(4):391-404. Epub 2021 Apr 20.

Institute of Neurobiology, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico 00901, USA.

Non-healing cutaneous wounds, including pressure, diabetic and venous ulcers, are wounds where the skin and underlying tissues die due to ischemia, infection, metabolic conditions, immunosuppression or radiation. Some can be eliminated with relatively straightforward techniques, although they may continue to grow in diameter and depth, becoming increasingly painful and never heal. Others respond more slowly or poorly to treatment, while others are recalcitrant to treatments. Read More

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