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Endocr Pract 2020 Jun 23. Epub 2020 Jun 23.

Department of Endocrinology, The Second Affiliated Hospital of Third Military Medical University, Chongqing, China.

: Moderate-to-severe subacute thyroiditis is clinically managed with 6-8 weeks of glucocorticoid therapy. However, no studies have evaluated short-term prednisone treatment for subacute thyroiditis. : This 24-week, prospective, single-blind, randomized controlled study enrolled patients (aged 18-70) with subacute thyroiditis who were hospitalized between August 2013 and December 2014. Read More

Arch Endocrinol Metab 2020 May-Jun;64(3):306-311

Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Objective: Ultrasound assessment plays an important role in the diagnosis, and monitoring of subacute thyroiditis (SAT). However, the relationship between ultrasonographic findings and severity or prognosis of the disease is not known. The aim of the present study was to evaluate the relationship between bilateral and unilateral disease involvement and severity and prognosis of the disease. Read More

J Endocrinol Invest 2020 Jun 5. Epub 2020 Jun 5.

Department of Internal Medicine, Ankara City Hospital, Ankara, Turkey.

J Endocrinol Invest 2020 Jun 2. Epub 2020 Jun 2.

Endocrine Unit, Department of Medicine and Surgery, University of Insubria-Ospedale Di Circolo Di Varese, ASST Dei Sette Laghi, Viale Borri, 57, 21100, Varese, Italy.

BMC Endocr Disord 2020 May 27;20(1):74. Epub 2020 May 27.

Department of Endocrinology, Yuebei People's Hospital, NO. 133 Huimin South Road, Shaoguan, Guangdong Province, China.

Background: Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning.

Methods: The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selected and divided into study group and control group according to whether they were diagnosed as SAT. Read More

Front Endocrinol (Lausanne) 2020 8;11:264. Epub 2020 May 8.

Department of Endocrinology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Thyrotoxicosis is commonly classified into several entities according to different etiologies. Identifying the causes of thyroid dysfunction is critical for the subsequent selection of treatment. The free triiodothyronine to free thyroxine ratio (fT/fT) is widely used but is still a controversial diagnostic measurement. Read More

Trials 2020 May 24;21(1):418. Epub 2020 May 24.

Department of Health Statistics, Shaanxi Key Laboratory of Free Radical Biology and Medicine and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Changle West Road No. 169, Xi'an, Shaanxi, 710032, China.

Background: Subacute thyroiditis (SAT) is the most common cause of thyroid pain. Several clinical guidelines recommend that patients who fail to respond to full doses of non-steroidal anti-inflammatory drugs (NSAIDs) should be treated instead with oral corticosteroid therapy. However, albeit strong recommendations, the treatment protocol is based on low-quality evidence and high-quality clinical trials are lacking with respect to the optimal initiation dosage and usage of corticosteroid. Read More

J Clin Endocrinol Metab 2020 07;105(7)

Endocrinology Unit I, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy.

Context: Subacute thyroiditis (SAT) is a thyroid disease of viral or postviral origin. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China, has spread rapidly worldwide and Italy has been severely affected by this outbreak.

Objectives: The objective of this work is to report the first case of SAT related to SARS-CoV-2 infection. Read More

Horm Metab Res 2020 May 19. Epub 2020 May 19.

Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

Endocr Pract 2020 May 14. Epub 2020 May 14.

From: Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Subacute thyroiditis (SAT) is an inflammatory thyroid disease that manifests with severe pain. The presence of the vitamin D receptor in immune system cells shows that vitamin D deficiency can trigger inflammatory diseases. The aim of the present study was to determine the prevalence of vitamin D deficiency in SAT patients, and the relationship between vitamin D level and permanent hypothyroidism and recurrence rate. Read More

Endocr Pract 2020 May 14. Epub 2020 May 14.

From: Department of Endocrinology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.

Graves' disease (GD) and the toxic phase of subacute thyroiditis (SAT), have similar clinical and biochemical presentations, and differentiating them requires sophisticated investigations. Since thyroid hormones have been noted to affect all hematologic cell lines, we have used the platelet lymphocyte ratio (PLR) - an index usually utilized in inflammatory or malignant disorders, to compare patients with and without thyrotoxicosis and to analyse it's use in distinguishing between patients with GD and SAT prior to therapy. This was a cross-sectional study conducted in the Department of Endocrinology, CMC Vellore, India. Read More

Horm Metab Res 2020 May 4. Epub 2020 May 4.

Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

Although subacute thyroiditis (SAT) is thought to be a self-limited inflammatory thyroid disease, the recurrence rate of SAT is approximately 10-20%. It is difficult for these patients to stop glucocorticoid treatment, and they are usually bothered with recurrent pain and the side effects of glucocorticoids for more than several months. We describe three cases who were diagnosed with recurrent subacute thyroiditis after a reduction in prednisolone (PSL) dose, either immediately upon the cessation of PSL or shortly thereafter. Read More

Front Endocrinol (Lausanne) 2020 28;11:47. Epub 2020 Feb 28.

Liaoning Provincial Key Laboratory of Endocrine Diseases, Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China.

The aim of the present prospective follow-up study was to explore the early indicators of hypothyroidism and the final changes in thyroid volume in subacute thyroiditis (SAT) patients. We enrolled 61 SAT patients and followed them up for 2 years to assess the incidence of hypothyroidism and changes in thyroid volume. Binary logistic regression and receiver operating characteristic (ROC) curves were used for data analysis. Read More

J Clin Transl Endocrinol 2020 Jun 19;20:100221. Epub 2020 Feb 19.

Division of Endocrinology, Georgetown University, Washington, DC, USA.

Background: Non-thyroid malignancies that metastasize to the thyroid gland are relatively rare. At one end of the spectrum they may only be identified at the time of autopsy. At the other extreme, they may be identified during the evaluation of a progressive malignancy. Read More

Indian J Med Res 2020 01;151(1):42-46

Department of Endocrinology, Command Hospital, Lucknow, Uttar Pradesh, India.

Background & Objectives: Thyrotoxic periodic paralysis (TPP) is an endocrine emergency presenting with acute-onset flaccid paralysis in a patient having thyrotoxicosis accompanied by hypokalaemia. This study was conducted to evaluate the clinical profile of patients with TPP presenting to three centres in India.

Methods: This retrospective, observational study was conducted at three tertiary care Armed Forces medical centres, located at Lucknow, Kolkata and Delhi. Read More

Am J Case Rep 2020 Mar 4;21:e920515. Epub 2020 Mar 4.

Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

BACKGROUND Fever of unknown origin (FUO) is a diagnosis that requires a demanding workup from physicians before confirming a diagnosis. Thyroid diseases are a rare cause of FUO. Subacute thyroiditis is an inflammatory disease that can lead to a wide spectrum of presentations. Read More

Rev Med Interne 2020 Jun 24;41(6):390-395. Epub 2020 Feb 24.

Service d'endocrinologie, diabétologie, maladies métaboliques, CHU de Dijon, 2, boulevard Maréchal-de-Lattre-de-Tassigny, 21000 Dijon, France; Unité Inserm LNC-UMR 1231, université de Bourgogne-Franche-Comté, Dijon, France. Electronic address:

Thyroiditis is a frequent and mostly benign disease that can sometimes disrupt the thyroid balance. Their diagnosis, as well as their aetiology, is a necessary step in the management of the patients. Painful thyroiditis includes acute thyroiditis of infectious origin and subacute thyroiditis. Read More

J Clin Med 2020 Feb 16;9(2). Epub 2020 Feb 16.

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital Research Institute, 281/289 Rzgowska St., 93-338 Lodz, Poland.

Subacute thyroiditis (SAT) is a thyroid inflammatory disease whose pathogenesis is still not completely defined. Previous viral infection is considered to be a triggering factor in genetically predisposed individuals. In about 70% of patients, susceptibility to SAT is associated with the allele. Read More

Asia Ocean J Nucl Med Biol 2020 ;8(1):54-57

Department of Nuclear Medicine, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey.

Objectives: The aim of this study was to determine whether technetium (Tc) uptake is a relevant method for the differential diagnosis of Graves disease and subacute thyroiditis and calculate its cutoff value in case of its relevancy.

Methods: A total of 69 patients, who were followed up (>3 months) in our hospital for thyrotoxicosis within 2015-2019 were enrolled in the study. Out of these 69 subjects, 39 patients had been diagnosed with Graves disease, and 30 of them had subacute thyroiditis. Read More

Pak J Med Sci 2020 Jan-Feb;36(2):240-245

Sedat Cetin, Medical Doctor, Department of Endocrinology, Sakarya University Medicine Faculty, Sakarya, Turkey.

Background &objective: Subacute Granulomatous Thyroiditis (De Quervain's Thyroiditis) is an acute painful inflammatory disease of the thyroid. We aimed to investigate easily accessible and cheap hemogram based parameters of Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte Ratio (PLR), and Mean Platelet Volume (MPV) in the follow up of inflammatory thyroid disease.

Methods: Patients admitted to Sakarya University Education and Research Hospital Endocrinology and Metabolism Outpatient Clinic and diagnosed as Subacute Granulomatous Thyroiditis between May 2017 and November 2018 were included in the study. Read More

Endocr J 2020 May 15;67(5):569-574. Epub 2020 Feb 15.

Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.

Subacute thyroiditis is a self-limited inflammatory disease and very few patients undergo ultrasonographic re-examination if no nodules are found at the initial examination. The objective of the study was to assess the diagnostic accuracy of ultrasonography in detecting nodular lesions in patients with subacute thyroiditis. We conducted a longitudinal study involving 710 patients with subacute thyroiditis who underwent ultrasonographic examinations in a single center between 2008 and 2018. Read More

J Endocr Soc 2020 Feb 16;4(2):bvz008. Epub 2019 Nov 16.

Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, USA.

Painful Hashimoto thyroiditis (pHT) is a rare diagnosis, and optimal treatment remains unclear. To better characterize pHT, PubMed, Embase, Scopus, and Web of Science indexes were searched for case reports or case series reporting pHT, published between 1951 and February 2019. Seventy cases reported in 24 publications were identified. Read More

J Clin Endocrinol Metab 2020 Jun;105(6)

Endocrinology Unit I, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Italy.

Context: The role of serum immunoglobulin (Ig)Ms in autoimmune thyroid diseases is uncertain.

Objective: We looked for IgMs to thyroglobulin (Tg) in patients with subacute thyroiditis (SAT), which is characterized by high serum Tg levels, the possible de novo appearance of IgGs to Tg (TgAb-IgGs), and no autoimmune sequelae.

Main Outcome Measures: TgAb-IgMs and TgAb-IgGs were detected by binding to Tg using the enzyme-linked immunosorbent assay (ELISA). Read More

Clin Chim Acta 2020 Apr 21;503:99-106. Epub 2020 Jan 21.

Department of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan; Department of Clinical Laboratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. Electronic address:

Objectives: Although a single nucleotide polymorphism in a specific receptor for lysophosphatidylserine, a lysophospholipid mediator involved in the immune system, is reportedly associated with Graves' disease, the association between lysophosphatidylserine and thyroid disorders remains to be elucidated. Therefore, we aimed to investigate the association between the level of phosphatidylserine-specific phospholipase A1 (PS-PLA1), which produces lysophosphatidylserine, and thyroid disorders.

Methods: We measured serum PS-PLA1 levels in the patients with various thyroid disorders (n = 120) and normal subjects (n = 58). Read More

AACE Clin Case Rep 2019 May-Jun;5(3):e184-e186. Epub 2019 Apr 25.

Objective: The objective of this report is to describe the presentation, disease course, and management of subacute thyroiditis (SAT) in children. SAT is a rare cause of thyroiditis in children and can be mistaken for acute suppurative thyroiditis, which may be more common in pediatrics.

Methods: We present a 7-year-old female, who had painful thyroid enlargement, fever, and thyrotoxicosis. Read More

Medicine (Baltimore) 2019 Dec;98(52):e18564

Department of Endocrinology, Inner Mongolia Baogang Hospital (The Third Affiliated Hospital of Inner Mongolia Medical University), Baotou, Inner Mongolia Autonomous Region, China.

Background: This study was designed to systematically evaluate the clinical efficacy and safety of ultrasound-guided intrathyroidal injection of glucocorticoids (GCs) versus routine oral administration of GCs for subacute thyroiditis (SAT) and to help seek evidence of evidence-based medicine (EBM) for ultrasound-guided intrathyroidal injection of GCs in the treatment of SAT.

Methods: Seven Chinese and English databases, including Chinese National Knowledge Infrastructure, Wanfang Data, VIP Information China Science and Technology Journal Database, SinoMed, PubMed, Cochrane Library, and Embase, were searched to collect randomized control trials on ultrasound-guided intrathyroidal injection of GCs in the treatment of SAT, which were published up to July 1, 2019. According to the method as described in Cochrane Reviewers' Handbook 5. Read More

Endocrine 2020 Apr 21;68(1):138-143. Epub 2019 Dec 21.

Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Background: Subacute thyroiditis (SAT) is an acute inflammatory disease of the thyroid. Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) values determined from peripheral blood, are accepted as available and practical indicators of systemic inflammation. The purpose of this study was to evaluate the value of hematological parameters in the diagnosis and prognosis of subacute thyroiditis patients. Read More

Am J Med 2020 Jun 17;133(6):e296-e297. Epub 2019 Dec 17.

Department of Internal Medicine and Clinical Immunology, Hôpital de La Conception, Assistance-Publique-Hôpitaux de Marseille, France. Electronic address:

Front Endocrinol (Lausanne) 2019 20;10:804. Epub 2019 Nov 20.

Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.

Lupus 2020 Jan 2;29(1):45-51. Epub 2019 Dec 2.

Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, PR China.

Background: We established a multi-centre online registry for primary Sjögren's syndrome (pSS) in China, and compared Chinese patients with those from other countries.

Methods: Data were from 87 rheumatology centres in 27 provinces. All 2986 patients had pSS according to the 2002 American-European Consensus Group or the 2016 American College of Rheumatology/European League Against Rheumatism. Read More

Horm Metab Res 2020 Jan 26;52(1):32-38. Epub 2019 Nov 26.

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.

Clinical symptoms of subacute thyroiditis (SAT) may be misleading and the proper diagnosis is significantly delayed, and many unnecessary therapeutic methods are used, including application of antibiotics. The purpose of the study is to analyze the reasons and frequency of delayed SAT diagnosis and unnecessary antibiotic treatment and to propose a simple algorithm to facilitate the diagnosis and prevent antibiotic abuse. Sixty-four SAT patients were divided into groups depending on the period of time from the first symptoms of SAT to diagnosis and on the unnecessary use of antibiotics. Read More

Eur Thyroid J 2019 Oct 15;8(5):268-272. Epub 2019 Jul 15.

Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.

Background: Subacute thyroiditis is generally believed to be induced by viral infection, and little attention has been paid to anti-thyroid antibodies.

Objectives: Our study aimed to assess the prevalence of anti-thyroid antibodies in patients with subacute thyroiditis.

Methods: Anti-thyroglobulin (TgAb) and anti-thyroid peroxidase antibodies (TPOAb) were measured with 4 different immunoassay kits currently used in 40 patients in the early phase of subacute thyroiditis. Read More

Sci Rep 2019 11 15;9(1):16899. Epub 2019 Nov 15.

Department of Endocrinology and Metabolism, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Subacute thyroiditis (SAT) is an inflammatory thyroid disease. The main purpose of the treatment is to relieve pain and control the inflammatory process. The aim of the present study was to evaluate the therapeutic effects of steroid and non-steroidal anti-inflammatory drugs (NSAIDs) in SAT. Read More

Turk J Med Sci 2019 12 16;49(6):1687-1692. Epub 2019 Dec 16.

Background/aim: The most common causes of thyrotoxicosis include Graves’ disease (GD), toxic multinodular goiter (TMNG), toxic adenoma (TA), and subacute granulomatous thyroiditis (SAT). In our study, we aimed to see whether neutrophil‐to‐lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet‐to‐lymphocyte ratio (PLR), and mean platelet volume (MPV) may be helpful in the differential diagnosis of these diseases.

Materials And Methods: We retrospectively analyzed the hospital records of the Endocrinology Clinic of our hospital between 2016 and 2019. Read More

Eur Thyroid J 2019 Jul 15;8(4):215-220. Epub 2019 Jul 15.

Division of Endocrinology - Department of Internal Medicine, University of Patras Medical School, Patras, Greece.

Background: Amiodarone-induced thyrotoxicosis (AIT) is a common and deleterious side effect of amiodarone use. There are two types of AIT, characterized by distinct pathogenic mechanisms and, hence, different treatments. Discriminating between type 1 (AIT1) and type 2 (AIT2) AIT is often very challenging. Read More

Exp Clin Endocrinol Diabetes 2019 Sep 23. Epub 2019 Sep 23.

Center for Endocrine and Metabolic Disorders, Reproductive and Prenatal Medicine, Endokrinologikum Hamburg Betriebsgesellschaft mbH, Hamburg, Germany.

Background: Subacute thyroiditis (SAT) is a rare inflammatory disease that presents diagnostic challenges. The underlying pathophysiology and prediction of outcomes are elusive. We investigated the long-term follow-up of SAT for up to 30 years and determined predictors for later hypothyroidism. Read More

Nuklearmedizin 2019 Sep 14;58(5):401-402. Epub 2019 Aug 14.

A 57-year-old female patient presented at the emergency department with fatigue, increased sweating, flushing symptoms, loss of appetite, drowsiness and severe diarrhea. Besides she also mentioned painful left-sided sore throat radiating to the temples, beginning two weeks after a flu and subfebrile temperatures. Read More

Genet Test Mol Biomarkers 2019 Sep 14;23(9):681-687. Epub 2019 Aug 14.

Department of Ultrasonography, Suzhou Wuzhong People's Hospital, Suzhou, China.

To compare fine-needle aspiration cytology (FNAC) with imprinted gene detection in the differential diagnosis of benign and malignant thyroid nodules. A total of 34 patients (35 cases of thyroid nodules) were examined using fine-needle puncture biopsy under ultrasound guidance, and the biopsy tissues were examined by cytologic examination and imprinted gene detection. Combined with postoperative pathology and follow-up results, the diagnostic value and consistency of the two methods were analyzed and compared. Read More

Clin Endocrinol (Oxf) 2019 11 10;91(5):652-659. Epub 2019 Sep 10.

Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark.

Objective: To investigate the impact of mandatory iodine fortification (IF) on the incidence of nosological subtypes of overt thyrotoxicosis and hypothyroidism.

Design: We identified and scrutinized all possible new cases of overt thyrotoxicosis and hypothyroidism in an open cohort in Northern Jutland (n = 309 434; 1 January 1997) during the years 2014-2016. Individual medical history was evaluated to verify and detail the incidence of overt thyroid dysfunction and for classification into nosological subtypes. Read More

BMC Endocr Disord 2019 Aug 6;19(1):86. Epub 2019 Aug 6.

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital - Research Institute, 281/289 Rzgowska St., 93-338, Lodz, Poland.

Background: The diagnosis of subacute thyroiditis (SAT) is based mainly on the presence of painful thyroid goitre and a significant increase in erythrocyte sedimentation rate (ESR). Proceeding according to these diagnostic criteria may lead to an incorrect diagnosis and treatment. Extremely dangerous is the situation when the diagnosis of SAT is erroneously made based on criteria other than ultrasound (US) image and fine needle aspiration biopsy (FNAB), which leads to delayed diagnosis of malignant tumour with poor prognosis. Read More

Diagn Cytopathol 2019 Dec 31;47(12):1251-1258. Epub 2019 Jul 31.

Department of Pathology, Acibadem University, Medical Faculty, Istanbul, Turkey.

Background: The aims of the study are to identify the diagnostic cytological features of subacute granulomatous thyroiditis (SGT), to compare our results with previous literature studies, and to investigate the cytological changes in SGT that mimic other thyroid lesions.

Methods: This retrospective study was conducted with 69 cases. The cytology slides were re-evaluated. Read More

Med Clin (Barc) 2019 Jul 24. Epub 2019 Jul 24.

Servicio de Endocrinología y Nutrición, Complejo Hospitalario Universitario de Ferrol, Xerencia de Xestión Integrada de Ferrol, Sergas, La Coruña, España.

J Assoc Physicians India 2018 Jun;66(6):112

Senior Consultant Physician, PARAS, HMRI, Patna, Bihar.

Rev Med Interne 2019 Nov 28;40(11):764-766. Epub 2019 Jun 28.

Service de médecine interne, Hôtel-Dieu, CHU Nantes, 1, place Alexis Ricordeau, Nantes 44000, France.

P R Health Sci J 2019 06;38(2):120-121

Medicine Department, University of Puerto Rico, Medical Sciences Campus, San Juan, PR.

Myasthenia gravis (MG) is an autoimmune disease that can mimic a variety of symptoms leading to a delay in diagnosis and treatment. We report the case of 48 year-old woman, in whom initial presentation of MG with predominance of bulbar symptoms was mistaken for thyroid disease complications. Subsequently, correct diagnosis and optimal management resulted on significant improvement of her functional state. Read More

J Coll Physicians Surg Pak 2019 Jun;29(6):S5-S7

Department of Endocrinology, Yangzhou University Affiliated Jiangdu People's Hospital of Yangzhou City, China.

A 55-year female patient presented with subacute thyroiditis (SAT) with a unique dynamic evolution, along with changes in the level of antithyroglobulin antibody, which has been rarely reported. Her thyrotoxicosis gradually worsened over the next three months. Severe hypothyroidism then rapidly developed and did not resolve. Read More

Clin Lab 2019 05;65(5)

J Cell Biochem 2019 Apr 8. Epub 2019 Apr 8.

Department of Endocrinology and Metabolism, Suqian First Hospital, Suqian, China.

Background: To explore the role of lidocaine on subacute thyroiditis (SAT) and the molecular mechanism.

Methods: SAT models were constructed by infecting adenovirus to thyroid follicular epithelial cells. Cells were randomly divided into five groups: model group, low lidocaine, middle lidocaine, high lidocaine, and a control group. Read More

Mediators Inflamm 2019 27;2019:5764061. Epub 2019 Feb 27.

Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.

Purpose: Hepcidin is an acute-phase protein involved also in regulation of iron homeostasis. The aim of the study was to prospectively assess for the first time the hepcidin concentration in patients with subacute thyroiditis (SAT), to identify biochemical determinants of hepcidin concentration and evaluate the potential role of hepcidin in SAT diagnosis and monitoring.

Methods: Out of 40 patients with SAT initially recruited, restrictive inclusion criteria fulfilled 21 subjects aged 45 ± 10 years and 21 healthy control subjects (CS). Read More