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Phytomedicine 2022 Jun 14;104:154254. Epub 2022 Jun 14.

School of Chinese Medicine, The University of Hong Kong, Hong Kong, China. Electronic address:

Background: Acupuncture has been an alternative approach for de Quervain's tenosynovitis (DQt), but trial evidence is still lacking.

Purpose: This study aimed to assess the efficacy of acupuncture in patients with DQt.

Study Design: A randomized controlled trial. Read More

Rofo 2022 Jun 15. Epub 2022 Jun 15.

Department of Radiology, University Hospital Wuerzburg, Germany.

Background:  The tendons of the hand run in close proximity to each other and within retinacular tunnels adjacent to articular joints, while forming intersections in characteristic locations. The enclosing tendon sheaths are often sites of systemic or infectious inflammation.

Method:  This review article outlines the different entities of tendon and tendon sheath pathology and their manifestation in the hands. Read More

J Hand Surg Asian Pac Vol 2022 May 27:1-11. Epub 2022 May 27.

Department of Orthopedic Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.

The involvement of digits in patients with multiple trigger digits often displays specific patterns. We aimed to determine the patterns of involvement of digits in multiple trigger digits and their association with patient-related factors and compare them to those of patients with a single trigger digit. All patients with trigger digits treated over a 2-year period were retrospectively examined in June 2020. Read More

Ann Med Surg (Lond) 2022 May 13;77:103620. Epub 2022 Apr 13.

Department of Orthopedics, Faculty of Medicine, Prince of Songkla University, 15 Karnjanavanich Road, Hat Yai, Songkhla, 90110, Thailand.

Introduction: This systematic review of randomized controlled trials was undertaken to assess whether any of the various currently used surgical interventions have better functional outcomes and less impairment or fewer surgical complications compared to the other common surgical interventions in de Quervain's disease.

Material And Methods: Relevant studies related to surgical interventions in de Quervain's disease based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines were identified from PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials for randomized controlled trials comparing surgical interventions in de Quervain's disease published from January 2000 to December 2020. Functional outcome and impairment were the primary outcomes assessed. Read More

J Hand Surg Am 2022 May 6. Epub 2022 May 6.

Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA.

Purpose: We sought to determine the effectiveness of corticosteroid injections (CSIs) for de Quervain tenosynovitis in patients with diabetes mellitus.

Methods: We retrospectively identified all patients with diabetes receiving a CSI for de Quervain tenosynovitis by 16 surgeons over a 2-year period. Data collected included demographic information, medical comorbidities, number and timing of CSIs, and first dorsal compartment release. Read More

Front Neurosci 2022 14;16:819010. Epub 2022 Apr 14.

Department of Neurology, Multiple Sclerosis Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.

Objective: Serum neurofilament light chain (sNfL) is increasingly used as a neuroaxonal injury biomarker in the elderly. Besides age, little is known about how other physiological factors like renal function and body mass index (BMI) alter its levels. Here, we investigated the association of estimated glomerular filtration rate (eGFR) and BMI with sNfL in a large sample of elderly patients with atrial fibrillation (AF). Read More

Hand Clin 2022 May;38(2):149-160

Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

In patients with radial-sided wrist pain, a myriad of possible etiologies exists and as such, a detailed history, examination, and, where indicated, imaging is obtained to try and aid with its diagnosis. The purpose of this article is to provide an overview of radial-sided wrist pain, diagnostic modalities and discuss current treatment options. More detailed information is out-of-scope for this article and if needed, we would guide the reader to seek out other selected texts, as indicated. Read More

Indian J Orthop 2022 Apr 29;56(4):628-633. Epub 2021 Nov 29.

Department of Radiology, University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Street, Ankara, Turkey.

Objectives: This study aimed to determine the radial styloid osseous changes observed on posteroanterior wrist radiographs of patients with de Quervain's tenosynovitis who required surgery or conservative treatment.

Materials And Methods: The surgically treated group included 24 patients with de Quervain's tenosynovitis. The conservative treatment group and the healthy control group each comprised 24 age- and sex-matched subjects. Read More

Infect Dis Rep 2022 Feb 21;14(1):142-154. Epub 2022 Feb 21.

Clinical and Research Department on Infectious Diseases, National Institute for Infectious Diseases "L. Spallanzani", Via Portuense 292, 00147 Rome, Italy.

De Quervain's thyroiditis, sometimes referred to as subacute thyroiditis (SAT), is the most common granulomatous disease of the thyroid, typically found after a viral infection in middle-aged women. The mRNA encoding for the angiotensin-converting enzyme-2 (ACE-2) receptor is expressed in follicular thyroid cells, making them a potential target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Besides infection, SARS-CoV-2 vaccines have also been implicated in SAT pathogenesis. Read More

Plast Reconstr Surg 2022 Feb;149(2):420-434

From the Departments of Medicine and Diagnostic Radiology and Divisions of Plastic and Reconstructive Surgery and Experimental Surgery, McGill University.

Background: The role of ultrasound in plastic surgery practice has grown significantly over the past decade, with notable applications for conditions of the upper extremity. Its utility for the management of de Quervain disease, however, remains to be established, and the prevalence of first dorsal compartment anatomical variations needs to be adequately assessed.

Methods: A systematic review was performed to evaluate the role of ultrasound in the diagnosis, anatomical characterization, and clinical management of de Quervain disease. Read More

BMJ Open 2021 12 23;11(12):e046891. Epub 2021 Dec 23.

Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan

Objective: Both physical diseases such as infection and chronic pain and psychological disorders such as depression have been associated with herpes zoster (HZ) reactivation. However, the relationship between de Quervain syndrome (DQS), a painful tenosynovitis and HZ remains unclear. We investigated whether DQS increases the risk of HZ reactivation. Read More

Clin Orthop Relat Res 2022 04;480(4):771-772

Department of Orthopaedic Surgery and Rehabilitation Services, The University of Chicago, Chicago, IL, USA.

Clin Case Rep 2021 Nov 22;9(11):e05109. Epub 2021 Nov 22.

Department of Faculty Surgery N 2 I.M.Sechenov First Moscow State Medical University Moscow Russia.

Viral infections are considered as etiologic factors of subacute thyroiditis. The true incidence of subacute thyroiditis, caused by SARS-CoV-2 infection, is probably considerable since it is often masked by more dramatic affection of the respiratory system. This report presents two female patients who developed de Quervain's thyroiditis after COVID-19 disease. Read More

J Hand Surg Asian Pac Vol 2021 Dec;26(4):555-562

Department of Orthopedic Surgery, Ilsan Paik Hospital, Inje University, Goyang, Korea.

: The intracompartmental septum isolating the extensor pollicis brevis (EPB) has been reported to affect the patient's response to nonsurgical treatment in de Quervain's disease. A simple physical test called the modified staged Finkelstein test was developed to evaluate the septum; the result of this test was compared with those of the pre-existing physical test (EPB entrapment test) and ultrasonographic (US) examination of the septum. : We retrospectively analyzed 52 patients who underwent two clinical tests, including the modified staged Finkelstein test and the EPB entrapment test, and US examination for de Quervain's disease. Read More

Clin Orthop Relat Res 2022 04;480(4):762-770

Department of Orthopedic Surgery, Medical Center of Chung-Ang University School of Medicine, Seoul, Republic of Korea.

Background: Ultrasonography (US)-guided steroid injections can improve the accuracy of injection in patients with de Quervain disease, especially in those with an intracompartmental septum. Although the main lesion of de Quervain disease in patients with a septum is a stenosing tenosynovitis of the extensor pollicis brevis (EPB), no report we know of has compared injection into the EPB subcompartment with an injection into both the abductor pollicis longus (APL) and EPB subcompartments. In this randomized trial, we compared the results of US-guided steroid injections targeting both subcompartments and the EPB subcompartment alone in patients with de Quervain disease. Read More

Front Endocrinol (Lausanne) 2021 29;12:707726. Epub 2021 Sep 29.

Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri Istituto di Ricovero e Cura a Carattere Scientifico, (IRCCS), Pavia, Italy.

Subacute thyroiditis (SAT) is a thyroid disease of viral or post-viral origin. Whether SAT represents a complication of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still unclear. Our aim was to systematically review the literature to 1) explore the size of the literature about SAT in COVID-19 and 2) evaluate the clinical characteristics of SAT. Read More

Curr Rev Clin Exp Pharmacol 2022 ;17(2):135-143

Health Information Science, in Medical Information Department, School of Management and Medical Information, Tehran University of Medical Science, Tehran, Iran.

Background: Subacute granulomatous thyroiditis (SAGT) is an inflammatory disease due to viral infections. Glucocorticoids, especially prednisolone (PSL), are one of the first approaches in the treatment of patients with SAGT. To date, no study has determined the lowest effective dose of prednisolone with the lowest recurrence rate in the treatment of SAGT. Read More

Somatosens Mot Res 2021 12 10;38(4):353-356. Epub 2021 Oct 10.

Department of Physical Medicine and Rehabilitation, Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.

Aim: In this study, we aimed to investigate frequency of de Quervain's tenosynovitis (DQT) in patient with idiopathic carpal tunnel syndrome (ICTS).

Material And Methods: We evaluated 356 hands of 310 patients who applied with the pre-diagnosis of ICTS. Patients who have pain over the radial styloid, pain on movement, tenderness over the first dorsal extensor compartment and also positive Finkelstein's test were accepted clinically DQT. Read More

J Wrist Surg 2021 Oct 15;10(5):377-384. Epub 2021 Mar 15.

Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

 The aim of this study was to compare the results of surgeries of the De Quervain's disease (DQD) through a randomized control trial.  We treated 40 cases of De Quervain's tenosynovitis in 2 groups: 20 patients by pulley release method and another 20 patients by pulley reconstruction method. The patients were selected as per the random table number. Read More

Acta Chir Orthop Traumatol Cech 2021 ;88(4 Suppl):21-26

NZZ MUDr. Luboš Hrazdira s.r.o., Brno.

This guide to ultrasound examination of the wrist and hand describes the basic scanning planes and contains corresponding high-resolution ultrasound images. The patient and probe positionings are explained in a simplified step-by-step manner using schematic drawings. This standard and simple examination technique seems to be an appropriate way to improve the learning curve of novice musculoskeletal sonographers. Read More

JBJS Rev 2021 09 10;9(9). Epub 2021 Sep 10.

Department of Orthopaedic Surgery, Northwell Health at North Shore University Hospital and Long Island Jewish Medical Center, New Hyde Park, New York.

»: Most cases of de Quervain tenosynovitis can be managed with nonoperative measures, and the mainstay of treatment is corticosteroid injection (CSI). The use of ultrasound may improve the accuracy of injections and can help to identify and localize injections to separate subcompartments.

»: For patients who are in the third trimester of pregnancy or breastfeeding, there is no contraindication to CSI as studies have shown that it can provide optimal symptomatic relief to the mother without impacting the baby. Read More

Medicine (Baltimore) 2021 Sep;100(35):e27067

Department of Orthopaedics and Traumatology, Gaziosmanpaşa Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Background: There is no clear information on the efficacy of corticosteroids, and splints in the treatment of patients with diabetes mellitus (DM). The aim of this study was to compare the outcomes of isolated corticosteroid injection therapy with splint treatment with corticosteroid injection in patients with and without DM.

Methods: 84 diabetics, and 84 healthy patients with a diagnosis of de Quervain's tenosynovitis were included in our study. Read More

Hand Surg Rehabil 2021 Dec 19;40(6):760-764. Epub 2021 Aug 19.

Department of Orthopedic Surgery, Clinique Saint-Luc Bouge, rue Saint-Luc 8, 5004 Bouge, Belgium.

Trapeziometacarpal prostheses have been used in the treatment of first carpometacarpal joint osteoarthritis for many years. No studies have demonstrated statistical superiority over gold-standard trapeziectomy, but they have been proved to enable shorter convalescence, better pain relief and faster functional recovery. The aims of the present study were to report functional results in a large cohort treated with the Touch® new-generation dual mobility trapeziometacarpal prosthesis, with comparison to results in the literature. Read More

Crit Care Med 2021 12;49(12):e1241-e1251

Department of Intensive Care Medicine, University Hospital Basel, Basel, Switzerland.

Objectives: To identify early predictors of postictal delirium in adult patients after termination of status epilepticus.

Design: Retrospective study.

Setting: ICUs at a Swiss tertiary academic medical center. Read More

Arch Bone Jt Surg 2021 May;9(3):345-349

Department of Orthopedics, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.

Hand and wrist disorders are common during pregnancy. Most of these problems develop during the third trimester when hormonal changes, fluid retention, and weight gain are maximum. This review study aimed to discuss pregnancy-related hand and wrist problems, and provide an overview of their pathology, clinical presentations, clinical examinations, and treatment options. Read More

Ochsner J 2021 ;21(2):120-122

Department of Orthopedics, Sports Medicine Institute, Ochsner Clinic Foundation, New Orleans, LA.

Inquiry 2021 Jan-Dec;58:469580211029607

Fuchinobe General Hospital, Sagamihara City, Kanagawa, Japan.

This study examined the association between hand disorders and time spent using information and communication devices. The participants in this study, conducted between January 2017 and 2020, were 150 healthy university students. They were tested for carpal tunnel syndrome and De Quervain's tenosynovitis. Read More

Int J Clin Pract 2021 Oct 6;75(10):e14581. Epub 2021 Jul 6.

International Federation of Medical Associations of Neural therapy, Ankara, Turkey.

Objective: De Quervain tenosynovitis is the most common cause of lateral wrist pain. The diagnosis can be made with the Finkelstein test when pain is provoked with wrist ulnar deviation. Conservative treatment including rest, non-steroidal anti-inflammatory medication and physical therapy is applied first, then there may be a need for corticosteroid injections, and in resistant cases, surgery. Read More

BMJ Case Rep 2021 Jun 21;14(6). Epub 2021 Jun 21.

Serviço de Imagiologia Geral, Centro Hospitalar Universitário Lisboa Norte EPE, Lisboa, Portugal.

J Hand Surg Am 2022 03 17;47(3):284.e1-284.e6. Epub 2021 Jun 17.

Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medicine, Chicago, IL. Electronic address:

Purpose: We hypothesized that repeat injections are associated with a decreased rate of success and that the success rate of injections correlates with patient comorbidities.

Methods: Using a commercially available insurance database, patients diagnosed with De Quervain tenosynovitis were identified using International Classification of Diseases, Ninth Revision and Tenth Revision codes and stratified by therapeutic interventions, including therapy, injections, and surgery, as well as comorbidities. Injection failure was defined as a patient receiving a repeat injection or subsequent surgical management. Read More