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J Hand Surg Am 2021 May;46(5):409-415

Curtis National Hand Center, MedStar Union Memorial Hospital, Baltimore, MD. Electronic address:

Orthobiologic agents are used as innovative adjuvant therapy to treat common upper-extremity pathology, including carpal tunnel syndrome, de Quervain tenosynovitis, and distal radius fractures. In this article, we perform a narrative review and evaluate current literature on orthobiologics in the upper extremity. Orthobiologics evaluated include bone morphogenetic proteins, platelet-rich plasma, bone marrow aspirate concentrate, mesenchymal stem cells, and amniotic membrane. Read More

Medicine (Baltimore) 2021 Apr;100(14):e24877

Jiangxi University of Traditional Chinese Medicine.

Background: De Quervain's disease is a kind of aseptic inflammation caused by repeated frictions of tendons in the tendon sheath of the styloid process of the radius. The main symptoms are protuberance and pain of the styloid process of the radius, accompanied by aggravation of pain during the movement of the wrist and thumb. The advantages of needle-knife are simple operation, obvious therapeutic effect and high safety. Read More

Musculoskelet Sci Pract 2021 06 27;53:102356. Epub 2021 Feb 27.

Universidad Peruana de Ciencias Aplicadas, School of Medicine, Lima, Peru.

Background: Previous research has reported an association between texting messages sent and De Quervain's tenosynovitis (DQT) symptomatology. However, these studies do not report smartphone dependence and DQT symptomatology.

Objective: We aimed to evaluate the association between problematic smartphone use (PSU) and DQT symptomatology among young adults. Read More

J Wrist Surg 2021 Feb 16;10(1):48-52. Epub 2020 Oct 16.

Division of Hand and Wrist Surgery, Rothman Orthopaedic Institute, Philadelphia, Pennsylvania.

 The routine use of plain radiography represents a significant expenditure and has been proven unnecessary in several orthopedic conditions. The utility of plain radiographs in the diagnosis of De Quervain's tenosynovitis (DeQ) is not clear.  This study evaluates whether plain radiographic findings routinely predict the need for surgery or alter treatment courses in the initial diagnosis of DeQ. Read More

Hand (N Y) 2021 Jan 19:1558944720988102. Epub 2021 Jan 19.

Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.

Background: Carpal tunnel syndrome (CTS), trigger finger (TF), and De Quervain tenosynovitis (DQ) are 3 common pathologies of the hand often treated with relatively simple surgical procedures. However, outcomes from these procedures can be compromised by postoperative complications. The aim of this study was to evaluate the association between diabetes, tobacco use, and obesity and the incidence of postoperative complications. Read More

Am J Phys Med Rehabil 2021 06;100(6):599-609

From the Department of Rehabilitation Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic (KM, YA); Physical and Rehabilitation Medicine Unit, "Luigi Sacco" University Hospital, A.S.S.T. Fatebenefratelli-Sacco, Milan, Italy (VR); Department of Rehabilitation and Sports Medicine, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic (JJ, KS); Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic (ON); and Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey (LÖ).

Abstract: Wrist/hand pain is a prevalent musculoskeletal condition with a great spectrum of etiologies (varying from overuse injuries to soft tissue tumors). Although most of the anatomical structures are quite superficial and easily evaluated during physical examination, for several reasons, the use of ultrasound imaging and guidance has gained an intriguing and paramount concern in the prompt management of relevant patients. In this aspect, the present review aims to illustrate detailed cadaveric wrist/hand anatomy to shed light into better understanding the corresponding ultrasonographic examinations/interventions in carpal tunnel syndrome, trigger finger, de Quervain tenosynovitis, rhizarthrosis, and the radiocarpal joint arthritis. Read More

FP Essent 2021 Jan;500:33-41

West Virginia University Department of Human Performance, 1 Medical Center Dr, Morgantown, WV 26506.

Common chronic hand pathologies seen by family physicians include carpal tunnel syndrome, trigger finger, and de Quervain tenosynovitis. Carpal tunnel syndrome is the most common compressive neuropathy of the upper extremity and is caused by compression of the median nerve at the wrist. Trigger finger, also known as stenosing tenosynovitis, is caused by a metaplasia of the A1 flexor tendon pulley and the flexor tendon causing increased friction and decreased space for tendon gliding in the flexor tendon sheath. Read More

BMJ Case Rep 2020 Dec 10;13(12). Epub 2020 Dec 10.

General Medicine, Chiba University Hospital, Chiba, Japan.

Medicine (Baltimore) 2020 Dec;99(49):e23483

The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.

Background: De Quervain disease (DQD) is a common clinical disease. As a strainingdisease, DQD is more common in women who frequently engage in manual operations. The main clinical symptoms are local pain and dysfunction. Read More

Semin Arthritis Rheum 2020 12 29;50(6):1280-1290. Epub 2020 Aug 29.

University Polyclinic Foundation A. Gemelli IRCCS, Rome, Italy.

Objectives: The management of wrist and hand's tenosynovitis remains challenging and needs to be individualized. Physical modalities are accepted among conservative treatments, but there is currently no systematic assessment of their role and efficacy. The aim of this review is to analyze the literature including studies dealing with the use of physical modalities in De Quervain disease, Dupuytren disease and trigger finger, in order to obtain indications for everyday clinical practice. Read More

J Clin Ultrasound 2021 May 6;49(4):398-400. Epub 2020 Oct 6.

Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.

Triggering due to de Quervain's disease is exceedingly rare. This is the first successfully diagnosed case of the snapping phenomenon of the extensor pollicis brevis (EPB) tendon in de Quervain's disease evaluated with preoperative dynamic ultrasonography, clearly demonstrated in an intraoperative video, and treated with decompression of EPB subcompartment only under a wide-awake surgery. Dynamic ultrasonographic images identified snapping caused by unsmooth excursion of an enlarged EPB tendon in a separate subcompartment. Read More

J Pak Med Assoc 2020 Aug;70(8):1314-1318

Department of Orthopedic Surgery, King Edward Medical University / Mayo Hospital, Lahore, Pakistan.

Objective: To compare the success of treatment between thumb spica cast with "methylprednisolone acetate injection" versus thumb spica cast alone for the treatment of de Quervain's disease as functional outcomes, complications and patient compliance.

Methods: A single blinded randomized controlled trial using a probability sampling technique was conducted from January 2014 to h February 2017at the Orthopaedic Unit II, King Edward Medical University / Mayo Hospital, Lahore. A total of 134 patients of both genders, between 30-60 years of age presented with wrist pain and diagnosed de Quervain's disease, were included in the study. Read More

Cureus 2020 Jul 29;12(7):e9461. Epub 2020 Jul 29.

Psychiatry, Lewisgale Medical Center, Salem, USA.

Thyroid storm is a rare, life-threatening condition characterized by severe or exaggerated clinical manifestations of thyrotoxicosis, commonly occurring in patients with longstanding, untreated hyperthyroidism such as Graves' disease and toxic nodular goiter. Subacute painful thyroiditis, also known as de Quervain thyroiditis, is a self-limited inflammatory disease of the thyroid gland that is characterized by neck pain, a tender diffuse thyroid goiter, elevated inflammatory markers, and a predictable course of thyroid function evolution. Rarely, it can cause thyroid storm. Read More

Plast Reconstr Surg 2020 07;146(1):105-126

From the Faculty of Medicine, McGill University; and the Division of Plastic and Reconstructive Surgery, McGill University Health Center.

Background: Nonsurgical management of de Quervain disease relies mainly on the use of oral nonsteroidal antiinflammatory drug administration, splint therapy, and corticosteroid injections. Although the latter is most effective, with documented success rates of 61 to 83 percent, there exists no clear consensus pertaining to conservative treatment protocols conferring the best outcomes. This article reports on all present conservative treatment modalities in use for the management of de Quervain disease and highlights specific treatment- and patient-related factors associated with the best outcomes. Read More

JAAPA 2020 Jul;33(7):49-50

Lindsey Brown Caruthers is an assistant professor in the PA program at Philadelphia College of Osteopathic Medicine Georgia in Suwanee, Ga., and practices emergency medicine at Emory University Hospital in Decatur, Ga.

Cureus 2020 Apr 16;12(4):e7692. Epub 2020 Apr 16.

Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Objectives  To assess the clinical and radiological features of repetitive stress injuries (RSIs), specifically de Quervain's (DQ) disease, tennis elbow (TE), and plantar fasciitis (PF). Methods This was an observational study conducted for eight months (March 2019 to September 2019) at the Orthopedic Department in collaboration with the Radiology Department. Clinically diagnosed RSI patients from both genders, aged between 30 and 50 years, were included in the study. Read More

J Hand Surg Asian Pac Vol 2020 Jun;25(2):133-136

Gold Coast University Hospital, Gold Coast, Australia.

De Quervain tenosynovitis (DQT) has been associated with repetitive movements of the radial first dorsal compartment. Since 2007, smartphones have become ingrained in society. Their functionality is primarily performed by dexterity of the user's thumb(s). Read More

Medicine (Baltimore) 2020 Mar;99(10):e19124

Department of Orthopedic Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Many smartphone users experience pain in the thumb/wrist. This pain can be due to certain types of hand injuries as well as inflammation of the extensor pollicis brevis and the abductor pollicis longus tendon sheaths, known as De Quervain tenosynovitis. The objective of this study was to evaluate the association between smartphone addiction and wrist/thumb pain and to determine the severity of the pain, as well as to calculate the prevalence of De Quervain tenosynovitis among medical students at King Abdulaziz University (KAU) in Jeddah. Read More

Orv Hetil 2020 Mar;161(11):419-424

Egészségtudományi Kar, Alapozó Egészségtudományi Intézet, Morfológiai és Fiziológiai Tanszék,Semmelweis EgyetemBudapest, Vas u. 17., 1088.

De Quervain's tendinopathy affects the region of the wrist and the hand. Thumb motion becomes painful. This illness is caused by a degenerative process rather than inflammation. Read More

Pain Ther 2020 Jun 25;9(1):129-142. Epub 2020 Feb 25.

Department of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.

Introduction: This compilation presents a comprehensive review of the literature on common chronic pain conditions of the hand. It briefly presents these common conditions with their biological background, diagnosis, and common management options. It then presents and compares the latest literature available for injection techniques to treat these diagnoses and compares the available evidence. Read More

J Ultrasound Med 2020 Aug 11;39(8):1553-1560. Epub 2020 Feb 11.

Department of Orthopedic Surgery, Hanyang University Hospital, Seoul, Korea.

Objectives: We performed preoperative ultrasonography (US) to detect the anatomic course of the superficial radial nerve (SRN) and dominant pathologic tendon of the first extensor compartment in de Quervain tenosynovitis.

Methods: We prospectively studied 27 patients (29 wrists) with de Quervain tenosynovitis who underwent surgical release of the first extensor compartment. Preoperatively, US was performed to evaluate the presence of the dominant pathologic tendon and the septum in the subcompartment, number of SRNs in the area of the surgical incision, and anatomic running course of the SRN. Read More

Acta Biomed 2019 12 23;90(4):451-456. Epub 2019 Dec 23.

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Introduction: Trapeziometacarpal (TMC) osteoarthritis is a common disease. Patients with advanced disease who have failed conservative treatment have different surgical options, including total joint prosthesis. The aim of this study was to investigate the long-term outcome and complications of trapeziometacarpal (TMC) total arthroplasty. Read More

Eur Radiol 2020 Apr 16;30(4):2220-2230. Epub 2019 Dec 16.

Radiology, Medical University of Vienna, Vienna, Austria.

Background: Although image-guided interventional procedures of the elbow and wrist are routinely performed, there is poor evidence in the literature concerning such treatments. Our aim was to perform a Delphi-based consensus on published evidence on image-guided interventional procedures around the elbow and wrist and provide clinical indications on this topic.

Methods: A board of 45 experts in image-guided interventional musculoskeletal procedures from the European Society of Musculoskeletal Radiology were involved in this Delphi-based consensus study. Read More

J Wrist Surg 2019 Dec 3;8(6):513-519. Epub 2019 Sep 3.

European Hand Ultrasound Surgery Society, Toulouse, France.

 de Quervain's syndrome is one of the main tendonitis of the wrist. The hypothesis of authors was that de Quervain's syndrome could be successfully treated with a specific ultrasound-guided percutaneous procedure, as it is for trigger finger.  Identification of the subcompartmentalization of the first extensor compartment was performed first, using the Hiranuma's classification, prior to the surgery. Read More

Clin Orthop Relat Res 2019 12;477(12):2759-2760

D. Ring, Associate Dean for Comprehensive Care, Professor of Surgery and Psychiatry, Dell Medical School-The University of Texas at Austin, Austin, TX, USA.

Clin Orthop Relat Res 2019 Dec;477(12):2750-2758

J. Blackburn, N. C. Chen, Hand and Arm Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA J. Blackburn, M. J. W. van der Oest, A-M. Vranceanu, J. T. Porsius, Integrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA M. J. W. van der Oest, R. W. Selles, J. T. Porsius, Department of Plastic, Reconstructive and Hand Surgery, Erasmus MC, Rotterdam, the Netherlands M. J. W. van der Oest, R. W. Selles, J. T. Porsius, Department of Rehabilitation Medicine, Erasmus MC, Rotterdam, the Netherlands M. J. W. van der Oest, R. Feitz, Hand and Wrist Center, Xpert Clinic, the Netherlands.

Background: Depression, anxiety, and pain catastrophizing have been associated with worse pain and function in studies of patients with de Quervain's tenosynovitis. Illness perceptions are the patient's thoughts and feelings about their illness. More negative perceptions of the illness such as the illness having a long duration or serious consequences are associated with worse physical function in patients with hand osteoarthritis. Read More

J Hand Surg Am 2020 Apr 19;45(4):289-297.e1. Epub 2019 Nov 19.

VOICES Health Policy Research Center, Department of Orthopaedic Surgery, Stanford University, Redwood City, CA. Electronic address:

Purpose: The use of routine physical therapy (PT) and occupational therapy (OT) after certain hand procedures, such as carpal tunnel release, remains controversial. The objective of this study was to evaluate baseline use, the change in use, variation in prescribing patterns by region, and costs for PT/OT after common hand procedures.

Methods: Outpatient administrative claims data from patients who underwent procedures for carpal tunnel syndrome, trigger finger, carpometacarpal arthritis, de Quervain tenosynovitis, wrist ganglion cyst, and distal radius fracture were abstracted from the Truven Health MarketScan database from 2007 to 2015. Read More

Medicine (Baltimore) 2019 Nov;98(46):e17765

Department of Acupuncture-Moxibustion, China-Japan Friendship Hospital.

Background: De Quervain disease (dQD) is a painful condition of the wrist that affects patients' quality of life and work ability. Acupotomy has been widely used in the treatment of dQD. It has been reported in many articles that acupotomy can improve the clinical symptoms of dQD. Read More

Aust J Gen Pract 2019 11;48(11):753-756

BSc (Occupational Therapy), Accredited Hand Therapist, Manager, Hand @ Upper Limb Centre, WA.

Background: Radial-sided wrist pain is a common patient complaint that can have a dramatic effect on the patient's productivity at work, sporting or artistic pursuits and activities of daily living.

Objective: The aim of this article is to outline key principles in the assessment and treatment of De Quervain's tenosynovitis.

Discussion: The correct diagnosis of this debilitating tendon condition and the seeking of early treatment yields excellent outcomes for patients. Read More

J Orthop Surg Res 2019 Nov 12;14(1):357. Epub 2019 Nov 12.

Department of Orthopaedic Surgery, Zhejiang Provincial People's Hospital and People's Hospital of Hangzhou Medical College, No. 158 Shangtang Road, Hangzhou, 310014, Zhejiang, China.

Purpose: To compare the time return to work and long-term results of tendoscopic versus open technique for de Quervain's disease.

Methods: From 2005 to 2013, either tendoscopic or open decompression was performed on 56 consecutive patients (56 wrists) with symptomatic de Quervain's disease despite a minimum of 3 months non-operative treatment. Of the 50 patients who met the inclusion criteria, 41 patients were followed-up for a mean of 7. Read More