1,008,963 results match your criteria Day Surgery Australia [Journal]


Dopaminergic Effects of Major Bath Salt Constituents 3,4-Methylenedioxypyrovalerone (MDPV), Mephedrone, and Methylone Are Enhanced Following Co-exposure.

Neurotox Res 2019 Mar 16. Epub 2019 Mar 16.

Department of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, Box 70594, Johnson City, TN, USA.

Designer drug mixtures popularized as "bath salts" often contain the synthetic cathinones 3,4 methylenedioxypyrovalerone (MDPV), mephedrone, and methylone in various combinations. However, most preclinical investigations have only assessed the effects of individual bath salt constituents, and little is known about whether co-exposure to MDPV, mephedrone, and methylone produces significant neuropharmacological interactions. This study evaluated and compared how MDPV, mephedrone, and methylone influence discrete brain tissue dopamine (DA) levels and motor stimulant responses in mice when administered alone and as a ternary mixture. Read More

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http://dx.doi.org/10.1007/s12640-019-00020-2DOI Listing
March 2019
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Pre- and post-transplant ponatinib for a patient with acute megakaryoblastic blast phase chronic myeloid leukemia with T315I mutation who underwent allogeneic hematopoietic stem cell transplantation.

Int J Hematol 2019 Mar 16. Epub 2019 Mar 16.

Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.

A 42-year-old female complaining of fever and night sweats was diagnosed with acute megakaryoblastic blast phase chronic myeloid leukemia (CML-BP). She had massive splenomegaly, left pleural effusion with leukemia infiltration, and moderate myelofibrosis. She received dasatinib monotherapy (140 mg/day) as for induction, after which her pleural effusion rapidly resolved and hematological remission was achieved. Read More

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http://dx.doi.org/10.1007/s12185-019-02628-8DOI Listing

Effect of biotin supplementation on milk yield of Girolando cows reared in a tropical climate.

Trop Anim Health Prod 2019 Mar 16. Epub 2019 Mar 16.

Escola de Veterinária e Zootecnia, Universidade Federal de Goiás, Goiânia, GO, 74001-970, Brazil.

The objective of this study was to evaluate the effect of biotin supplementation on milk yield and the reproductive efficiency in Girolando cows. The study was conducted on a dairy farm located in central Brazil, between April 2012 and December 2016. Thirty-six Girolando cows in their first lactation were used. Read More

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http://dx.doi.org/10.1007/s11250-019-01862-wDOI Listing

Human Endothelial Colony Forming Cells Express Intracellular CD133 that Modulates their Vasculogenic Properties.

Stem Cell Rev 2019 Mar 16. Epub 2019 Mar 16.

Sorbonne Paris Cité, Université Paris Descartes, Paris, France.

Stem cells at the origin of endothelial progenitor cells and in particular endothelial colony forming cells (ECFCs) subtype have been largely supposed to be positive for the CD133 antigen, even though no clear correlation has been established between its expression and function in ECFCs. We postulated that CD133 in ECFCs might be expressed intracellularly, and could participate to vasculogenic properties. ECFCs extracted from cord blood were used either fresh (n = 4) or frozen (n = 4), at culture days <30, to investigate the intracellular presence of CD133 by flow cytometry and confocal analysis. Read More

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http://dx.doi.org/10.1007/s12015-019-09881-8DOI Listing

Therapeutic Prospective of a Spore-Forming Probiotic-Bacillus clausii UBBC07 Against Acetaminophen-Induced Uremia in Rats.

Probiotics Antimicrob Proteins 2019 Mar 16. Epub 2019 Mar 16.

Department of Pharmacology, SSR College of Pharmacy, Silvassa, U. T. of Dadra Nagar & Haveli, 396230, India.

To screen Bacillus clausii UBBC07 as a putative probiotic strain and to examine the protective effect of probiotic-B. clausii UBBC07 spore on uremia on rats induced by acetaminophen. In vitro tests performed to screen potential probiotic strains were gastric and bile acid resistance and ability to reduce pathogen adhesion to surfaces. Read More

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http://dx.doi.org/10.1007/s12602-019-09540-xDOI Listing

Negative impact of proteinuria on circulating myeloid dendritic cells.

Clin Exp Nephrol 2019 Mar 16. Epub 2019 Mar 16.

Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.

Background: A decrease in absolute numbers (abs.) of circulating dendritic cells (DCs) and recruitment into target organs has been reported, but whether the level of proteinuria associates with circulating DC abs. has not been clarified. Read More

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http://dx.doi.org/10.1007/s10157-019-01724-7DOI Listing

Maternal L-proline supplementation during gestation alters amino acid and polyamine metabolism in the first generation female offspring of C57BL/6J mice.

Amino Acids 2019 Mar 16. Epub 2019 Mar 16.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, 100193, China.

We recently reported that dietary supplementation with L-proline (proline) during gestation improved embryonic survival in C57BL/6J mice. The objective of the present study was to test the hypothesis that the effect of maternal proline supplementation on embryonic survival can be carried forward to the first generation female offspring. In the F0 generation, pregnant dams were fed a purified diet supplemented with 0 (control) or 5 g proline/kg diet. Read More

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http://dx.doi.org/10.1007/s00726-019-02717-2DOI Listing

Moderate consumption of fermented alcoholic beverages diminishes diet-induced non-alcoholic fatty liver disease through mechanisms involving hepatic adiponectin signaling in mice.

Eur J Nutr 2019 Mar 16. Epub 2019 Mar 16.

Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Althanstraße 14 (UZA II), 1090, Vienna, Austria.

Purpose: Results of some epidemiological studies suggest that moderate alcohol consumption may be associated with a decreased risk to develop NAFLD. Here, the effect of the consumption of moderate beer and diluted ethanol, respectively, on the development of NAFLD were assessed.

Methods: Female C57BL/6J mice were fed a control diet (C-D) or a diet rich in fructose, fat and cholesterol (FFC) enriched isocalorically and isoalcoholically with beer (FFC + B) or plain ethanol (FFC + E) (2. Read More

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http://dx.doi.org/10.1007/s00394-019-01945-2DOI Listing

Assessment of left ventricular outflow tract and aortic root: comparison of 2D and 3D transthoracic echocardiography with multidetector computed tomography.

Eur Heart J Cardiovasc Imaging 2019 Mar 16. Epub 2019 Mar 16.

The Heart Center, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark.

Aims: Accurate echocardiographic assessment of left ventricular outflow tract (LVOT) and the aortic root is necessary for risk stratification and choice of appropriate treatment in patients with pathologies of the aortic valve and aortic root. Conventional 2D transthoracic echocardiographic (TTE) assessment is based on the assumption of a circular shaped LVOT and aortic root, although previous studies have indicated a more ellipsoid shape. 3D TTE and multidetector computed tomography (MDCT) applies planimetry and are not dependent on geometrical assumptions. Read More

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http://dx.doi.org/10.1093/ehjci/jez045DOI Listing

Misclassification of Myocardial Injury as Myocardial Infarction: Implications for Assessing Outcomes in Value-Based Programs.

JAMA Cardiol 2019 Mar 17. Epub 2019 Mar 17.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

Importance: Similar to other patients with acute myocardial infarction, patients with type 2 myocardial infarction (T2MI) are included in several value-based programs, including the Hospital Readmissions Reduction Program and the Hospital Value-Based Purchasing Program. To our knowledge, whether nonischemic myocardial injury is being misclassified as T2MI is unknown and may have implications for these programs.

Objective: To determine whether patients with nonischemic myocardial injury are being miscoded as having T2MI and if this has implications for 30-day readmission and mortality rates. Read More

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http://dx.doi.org/10.1001/jamacardio.2019.0716DOI Listing

Comparison between Operative and Non-Operative Treatment of the Medial Collateral Ligament: Histological and Ultrastructural Findings during Early Healing in the Epiligament Tissue in a Rat Knee Model.

Cells Tissues Organs 2019 Mar 15:1-17. Epub 2019 Mar 15.

Department of Anatomy, Histology and Embryology, Medical University of Sofia, Sofia, Bulgaria.

The medial collateral ligament of the knee joint is one of the most commonly injured ligaments of the knee. Recent data have shown that the thin layer of connective tissue covering the ligament, known as the epiligament, is essential for its nutrition and normal function, as well as its healing after injury. The aim of the present study was to investigate and compare the changes in the epiligament of the medial collateral ligament which occurred during operative and non-operative treatment throughout the first month after injury. Read More

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http://dx.doi.org/10.1159/000496985DOI Listing

Triamcinolone Acetonide versus Fluticasone Propionate in the Treatment of Perennial Allergic Rhinitis: A Randomized, Parallel-Group Trial.

Int Arch Allergy Immunol 2019 Mar 15:1-10. Epub 2019 Mar 15.

Department of Clinical Allergology of Russian Medical Academy of Postdiploma Education, Moscow, Russian Federation.

Background: Intranasal sprays are recommended as targeted therapy for allergic rhinitis (AR). Triamcinolone acetonide is a nasal corticosteroid preparation indicated for the treatment of seasonal and perennial AR (PAR) in different countries worldwide.

Objectives: In order to determine the efficacy of triamcinolone acetonide in the treatment of PAR, the non-inferiority of triamcinolone acetonide to fluticasone propionate was assessed in Russian adults. Read More

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http://dx.doi.org/10.1159/000497160DOI Listing

Variations in the phytoplankton community due to dust additions in eutrophication, LNLC and HNLC oceanic zones.

Sci Total Environ 2019 Feb 28;669:282-293. Epub 2019 Feb 28.

Key Laboratory of Marine Environment and Ecology, Ministry of Education of China, Ocean University of China, Qingdao 266100, China; Laboratory for Marine Ecology and Environmental Sciences, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China. Electronic address:

Dust deposition can bring nutrients and trace elements to the upper ocean and affect phytoplankton growth and community structure. We conducted a comparative study using on-board microcosm experiments amended with varying amounts of dust (0.2, 1, and 2 mg L) in the East China Sea (eutrophic zone), the subtropical gyre (low-nutrient and low-chlorophyll zone, LNLC), and the Kuroshio-Oyashio transition region (high-nutrient and low-chlorophyll zone, HNLC) of the Northwest Pacific Ocean. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.068DOI Listing
February 2019

The association between cold spells and admissions of ischemic stroke in Hefei, China: Modified by gender and age.

Sci Total Environ 2019 Mar 1;669:140-147. Epub 2019 Mar 1.

Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China; Anhui Province Key Laboratory of Major Autoimmune Disease, China. Electronic address:

Background: Some studies have discovered that low ambient temperatures were associated with increased risk of the incidence of ischemic stroke. Although the frequency of extreme weather events is increasing, few studies have studied the effects of cold wave on ischemic stroke.

Objective: The purpose of this study was to explore the association between cold waves and ischemic stroke onset and further to explore how this association was modified by cold spell characteristics and individual-level factors. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.452DOI Listing

Simultaneous determination of three saponins in human plasma after oral administration of compound danshen dripping pills by LC-MS/MS and its application in a pharmacokinetic study.

J Pharm Biomed Anal 2019 Mar 5;169:254-259. Epub 2019 Mar 5.

Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin 300410, China; State Key Laboratory of Core Technology in Innovation Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin 300410, China; Tasly Pharmaceuticals Inc, Rockville, MD 20850, USA.

As one of the main constituents of Compound Danshen Dripping Pills (CDDP), Panax notoginseng (PN) plays a pivotal role in the treatment of cardiovascular diseases. Numerous researches have proved that the dammarane type saponins including notoginsenoside R1 (NR1), ginsenoside Rg1 (GRg1) and ginsenoside Rb1 (GRb1) are the main bioactive components of PN in CDDP. An efficient, realiable and sensitive liquid chromatography tandem-mass spectrometry (LC-MS/MS) analysis method for simultaneously detecting NR1, GRg1 and GRb1 in human plasma was established and applied to the pharmacokinetics study of the three PN saponins after oral administration of CDDP. Read More

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http://dx.doi.org/10.1016/j.jpba.2019.03.008DOI Listing

Improved sample treatment for the determination of flavonoids and polyphenols in sweet potato leaves by ultra performance convergence chromatography-tandem mass spectrometry.

J Pharm Biomed Anal 2019 Mar 4;169:245-253. Epub 2019 Mar 4.

Department of Pharmaceutics, School of Pharmacy, Peking University, Beijing, China.

This work reports the development and application of a multi-compound analysis method for the determination of 17 flavonoids and polyphenols in sweet potato leaves. Samples were processed by microwave-enhanced accelerated solvent extraction under low pressure at 120 °C for 10 min. Salting-out homogeneous liquid-liquid extraction was used to remove water and water-soluble impurities from the extract before ultra performance convergence chromatography-tandem mass spectrometry analysis. Read More

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http://dx.doi.org/10.1016/j.jpba.2019.03.003DOI Listing
March 2019
2.979 Impact Factor

Prospective feasability study of ambulatory surgery for pelvic organ prolapse.

Eur J Obstet Gynecol Reprod Biol 2019 Mar 5;236:36-40. Epub 2019 Mar 5.

Gynecologic Surgery Department, CMC Beau Soleil, Montpellier, France.

Study Objective: The aim of this study was the evaluation of ambulatory surgery (AS) rate for pelvic organ prolapse (POP).

Design: It was a prospective observational study.

Design Classification: Level II-2. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03012115193004
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http://dx.doi.org/10.1016/j.ejogrb.2019.01.019DOI Listing
March 2019
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Combined Partial Denitrification (PD)-Anammox: A method for high nitrate wastewater treatment.

Environ Int 2019 Mar 14;126:707-716. Epub 2019 Mar 14.

National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology, Engineering and Technology Research Center of Beijing, Beijing University of Technology, Beijing 100124, China.

Elimination of nitrogen pollution from wastewater containing high-strength nitrate (NO-N) is a significant issue to prevent deterioration of water quality and eutrophication of receiving water body. Traditional denitrification process faces several challenges including the huge organic carbon demand, intermediate products accumulation, and long acclimatization period. In this study, an efficient solution was given by a novel two-stage Partial Denitrification (PD)-Anammox process. Read More

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http://dx.doi.org/10.1016/j.envint.2019.03.007DOI Listing

Environmental predictors of objectively measured out-of-home time among older adults with cognitive decline.

Arch Gerontol Geriatr 2019 Jan 28;82:259-265. Epub 2019 Jan 28.

Department of Preventive Gerontology, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi 474-8511, Japan.

Background: Older adults with cognitive decline are vulnerable to various health problems. Going out of home for longer time could be beneficial for their health. Identifying modifiable predictors is essential for developing effective strategies that would increase time spent out-of-home by older adults. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01674943193002
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http://dx.doi.org/10.1016/j.archger.2019.01.021DOI Listing
January 2019
1 Read

Early hMSC morphology and proliferation on model polyelectrolyte multilayers.

Colloids Surf B Biointerfaces 2019 Feb 28;178:276-284. Epub 2019 Feb 28.

Department of Plastics Engineering, University of Massachusetts Lowell, One University Ave, Lowell, MA, 01854, United States. Electronic address:

Polyelectrolyte multilayers (PEMs) are a category of materials commonly used as coatings on surfaces that interact with cells. The properties of PEMs have been established to be controlled by not only polyelectrolyte choice, but by the identity of the initially applied (bottom) layer. In this work, 5-bilayer PEMs consisting of poly(diallyldimethylammonium chloride) (PDADMAC) and poly(sodium 4-styrenesulfonate) (PSS) were coated on gold-sputtered quartz substrates with different first layer materials. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.02.055DOI Listing
February 2019

Adjunctive ondansetron for schizophrenia: A systematic review and meta-analysis of randomized controlled trials.

J Psychiatr Res 2019 Mar 5;113:27-33. Epub 2019 Mar 5.

Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China. Electronic address:

The serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor has been implicated in the pathogenesis of schizophrenia. This meta-analysis of randomized controlled trials (RCTs) examined the efficacy and safety of adjunctive ondansetron, a potent 5-HT3 receptor antagonist, in the treatment of schizophrenia. Only RCTs examining adjunctive ondansetron for schizophrenia were included. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2019.02.024DOI Listing

Everyday discrimination indirectly influences smoking cessation through post-quit self-efficacy.

Drug Alcohol Depend 2019 Feb 28;198:63-69. Epub 2019 Feb 28.

Oklahoma Tobacco Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Department of Family and Preventive Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Background: Although studies have shown an association between discrimination and current smoking, the influence of discrimination on smoking cessation is an understudied area in tobacco research. The current study evaluated the influence of everyday discrimination on smoking cessation and examined self-efficacy as a potential mediator of this association.

Methods: Participants (N = 146), who were recruited from a safety-net hospital in Dallas County, Texas, from 2011 to 2013, completed a self-report measure of perceived discrimination one week before the scheduled quit attempt and self-efficacy for quitting was assessed one day after the scheduled quit date. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03768716193006
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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.033DOI Listing
February 2019
1 Read

Cured from a Cardiac Myxoma? Brain Intraparenchymal Hemorrhage in a Patient with a 10-year Successfully Resected Cardiac Myxoma.

World Neurosurg 2019 Mar 13. Epub 2019 Mar 13.

Lyerly Neurosurgery / Baptist Neurological Institute, Jacksonville, FL. Electronic address:

Background: A cardiac myxoma (CM) is the most common primary tumor of the heart. This case report highlights that for metastatic cardiac myxomas, even after a successful total resection, there is a small but real risk of recurrence that can manifest as late as 10 years after initial tumor resection.

Case Description: We present the case of a 53-year-old woman who visited the emergency room after a 4-day worsening right-sided weakness. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.295DOI Listing

Reduced facial swelling and incision numbness after Q-modified eversion carotid endarterectomy in patients with severe carotid stenosis.

World Neurosurg 2019 Mar 13. Epub 2019 Mar 13.

Department of Vascular and Endovascular Surgery, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. Electronic address:

Background: Carotid endarterectomy (CEA), especially the eversion carotid endarterectomy (ECEA), is a standard treatment for carotid artery stenosis, but it still has deficiencies. We describe a modified ECEA technique which focuses on the quality of life (QoL), called Q-modified eversion carotid endarterectomy (QCEA). It mainly modifies the skin incision, surgical approach, and arterial anastomosis. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.205DOI Listing

Effects of citrate ester plasticizers and bis (2-ethylhexyl) phthalate in the OECD 28-day repeated-dose toxicity test (OECD TG 407).

Environ Res 2019 Mar 8;172:675-683. Epub 2019 Mar 8.

Department of Life Science and Institute for Natural Sciences, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea. Electronic address:

Citrate esters are considered functional alternatives to phthalate plasticizers, but their toxicity remains poorly understood. The toxicity of citrate esters, including triethyl 2-acetylcitrate (ATEC) and trihexyl O-acetylcitrate (ATHC), were examined together with that of bis (2-ethylhexyl) phthalate (DEHP) using the Organization for Economic Co-operation and Development Test Guideline 407 (OECD TG407). Following 28-day oral administration, no significant differences in body weight or the weight of the brain, pituitary, heart, epididymis, seminal vesicles, or coagulating gland were found between the vehicle control and DEHP, ATEC or ATHC groups. Read More

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http://dx.doi.org/10.1016/j.envres.2019.03.004DOI Listing

Profiles, variability and predictors of concentrations of blood trihalomethanes and urinary haloacetic acids along pregnancy among 1760 Chinese women.

Environ Res 2019 Mar 8;172:665-674. Epub 2019 Mar 8.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental health (incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China. Electronic address:

Blood trihalomethanes (THMs) and urinary haloacetic acids (HAAs) are the leading candidate biomarkers for disinfection byproduct (DBP) exposure. However, no studies have assessed the exposure profiles, temporal variability, and potential predictors of these biomarkers during pregnancy. Here we collected blood (n = 4304) and urine samples (n = 4165) from 1760 Chinese pregnant women during early, mid-, and late pregnancy, which were separately analyzed for 4 THMs and 2 HAAs. Read More

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http://dx.doi.org/10.1016/j.envres.2019.03.017DOI Listing

A view of the maternal inheritance of Espírito Santo populations: The contrast between the admixed and Pomeranian descent groups.

Forensic Sci Int Genet 2019 Mar 6;40:175-181. Epub 2019 Mar 6.

Núcleo de Genética Humana e Molecular (NGHM), Universidade Federal do Espírito Santo (UFES), Fernando Ferrari Avenue, 514 - Goiabeiras, Vitória, Espírito Santo, 29075-910, Brazil; Programa de Pós-Graduacão em Biotecnologia, Universidade Federal do Espírito Santo (UFES), Marechal Campos Avenue, 1468 - Bonfim, Vitória, Espírito Santo, 29047-105, Brazil.

In addition to its valuable utility in forensic investigations, mitochondrial DNA (mtDNA) analysis is a reliable tool to uncover the origins of admixed populations, such as Brazilians. The state of Espírito Santo (ES), similar to other coastal Brazilian states, has a population shaped by 3 main ancestral roots: Amerindian, African and European. Among the latter, the Pomeranian descendants stand out due to the preservation of the traditional aspects of their culture, especially the Pomeranian language. Read More

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http://dx.doi.org/10.1016/j.fsigen.2019.03.007DOI Listing

MiRNA profiling of plasma-derived exosomes from dairy cows during gestation.

Theriogenology 2019 Mar 7;130:89-98. Epub 2019 Mar 7.

Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China. Electronic address:

Exosomes, one kind of extracellular vesicles, are released under abnormal and normal physiological conditions. An understanding of plasma-derived exosomal microRNA (miRNA) profiles during pregnancy will significantly contribute to knowledge of maternal-fetal communication in ruminants. In this study, we isolated plasma-derived exosomes from dairy cows during early (∼60 days, gestational day (G_D) 60), mid (∼150 days, G_D 150) and late (∼240 days, G_D 240) pregnancy. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2019.03.001DOI Listing

Oocyte quality and heat shock proteins in oocytes from bovine breeds adapted to the tropics under different conditions of environmental thermal stress.

Theriogenology 2019 Mar 7;130:103-110. Epub 2019 Mar 7.

State University of Mato Grosso do Sul, Animal Science, Aquidauana, Mato Grosso do Sul, Brazil; Federal University of Mato Grosso do Sul, Veterinary Science, Campo Grande, Mato Grosso do Sul, Brazil. Electronic address:

In order to evaluate the influence of thermal stress on physiological parameters, and the oocyte quality of Girolando (n = 12) and adapted Pantaneira (n = 12) cattle, twelve sessions of ultrasound guided follicular aspiration (OPU) were performed, between January and November 2014 (during dry (May-September) and rainy season (October-April) in Brazil). The recovered cumulus-oocyte complexes (COCs) were selected and classified, according to quality, immediately after OPU. The oocytes were then stored in 3% paraformaldehyd before conducting immunofluorescence analysis under confocal microscopy to identify HSP70 and 90 proteins. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2019.02.039DOI Listing

Comorbid sensorimotor and emotional profiles in the forced swim test immobility and predictive value of a single assay in very old female mice.

Exp Gerontol 2019 Mar 13. Epub 2019 Mar 13.

Institute of Neuroscience, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Barcelona, Spain; Medical Psychology Unit, Department of Psychiatry and Forensic Medicine, School of Medicine, Campus Bellaterra, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Barcelona, Spain. Electronic address:

The increase of prevalence of mental health problems in the elderly due to the aging of the population becomes an outstanding issue since in most individuals it happens in an already complex multimorbid scenario that may include frailty and age-related medical conditions. Depression, soon the major cause of global disease burden, can be found as an age-related comorbidity and frailty, or as part of neurodegenerative diseases and where females are more vulnerable to it. Thought the multifactorial aetiology and heterogeneous nature of depression render it difficult to be modelled in animals, active behaviours elicited in the Forced Swimming Test (FST) are used to screen antidepressant treatments. Read More

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http://dx.doi.org/10.1016/j.exger.2019.03.004DOI Listing

The phase of the estrous cycle modifies the endocrine, metabolic and behavior rhythms in ewes.

Physiol Behav 2019 Mar 13. Epub 2019 Mar 13.

Departamento de Fisiología, Facultad de Veterinaria, Universidad de la Republica, Lasplaces 1550, Montevideo 11600, Uruguay. Electronic address:

The aim of this study was to compare circadian rhythms of serum cortisol and insulin concentrations, glycemia, glycemia:insulin ratio (GLY:INS), rectal, vaginal and surface (ST) temperatures as well behavioral patterns during the follicular (FOL) and luteal (LUT) phases in ewes. All the variables were measured during both phases of the estrous cycle in 8 West African ewes during a 24 h period. Cortisol concentrations were greater during FOL than LUT (30. Read More

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http://dx.doi.org/10.1016/j.physbeh.2019.03.011DOI Listing

Comparison of graft-acquisition and early direct charges of haploidentical related donor transplantation versus umbilical cord blood transplantation.

Biol Blood Marrow Transplant 2019 Mar 13. Epub 2019 Mar 13.

Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.

Alternative donor allogeneic hematopoietic cell transplants (allo-HCT), such as double UCB transplants (dUCBT) and haploidentical related donor transplants (haplo-HCT) have been shown to be safe and effective in adult patients who do not have an HLA-identical sibling or unrelated donor available. Most transplant centers have committed to one of the two alternative donor sources, even though there is a lack of published randomized data directly comparing outcomes and comparative data on cost effectiveness of dUCBT versus haplo-HCT. We conducted a retrospective study to evaluate and compare the early costs and charges of haplo-HCT and dUCBT in the first 100 days at two US transplant centers. Read More

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http://dx.doi.org/10.1016/j.bbmt.2019.03.013DOI Listing

Changes in Discharge to Rehabilitation: Potential Unintended Consequences of Medicare Total Hip Arthroplasty/Total Knee Arthroplasty Bundled Payments Should They Be Implemented on a Nationwide Scale.

J Arthroplasty 2019 Feb 18. Epub 2019 Feb 18.

Department of Orthopaedics & Rehabilitation, Yale School of Medicine, New Haven, CT.

Background: As a part of the 2010 Affordable Care Act, Medicare was committed to changing 50% of its reimbursement to alternative payment models by 2018. One strategy included introduction of "bundled payments" or a fixed price for an episode of care. Early studies of the first operative bundles for elective total hip and knee arthroplasty (THA/TKA) suggest changes in discharge to rehabilitation. Read More

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http://dx.doi.org/10.1016/j.arth.2019.01.068DOI Listing
February 2019

The protective role of spermine against male reproductive aberrations induced by exposure to electromagnetic field - An experimental investigation in the rat.

Toxicol Appl Pharmacol 2019 Mar 13. Epub 2019 Mar 13.

INSERM UMRS-1144, Paris-Diderot University, Paris, France; Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France.

The exponentially increasing use of electromagnetic field (EMF)-emitting devices imposes substantial health burden on modern societies with particular concerns of male infertility. Limited studies have addressed the modulation of this risk by protective agents. We investigated the hazardous effects of rat exposure to EMF (900 MHz, 2 h/day for 8 weeks) on male fertility and evaluated the possible protective effect of the polyamine, spermine, against EMF-induced alterations. Read More

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http://dx.doi.org/10.1016/j.taap.2019.03.009DOI Listing

Robotic assisted Shoulder Rehabilitation Therapy Effectively Improved Post-stroke Hemiplegic Shoulder Pain: A Randomized Controlled Trial.

Arch Phys Med Rehabil 2019 Mar 13. Epub 2019 Mar 13.

Department of Rehabilitation Medicine, Chungbuk National University College of Medicine, Cheongju, Republic of Korea. Electronic address:

Objective: The purpose of this study was to investigate the therapeutic effects of a newly developed shoulder robot on post-stroke hemiplegic shoulder pain DESIGN: Prospective, single-blind randomized controlled trial.

Setting: Inpatient department of a tertiary university hospital.

Participants: Hemiplegic shoulder pain patients (n=38) were consecutively recruited and randomly assigned to an intervention or control group. Read More

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http://dx.doi.org/10.1016/j.apmr.2019.02.003DOI Listing

Prehospital quick sequential organ failure assessment score to predict in-hospital mortality among patients with trauma.

Am J Emerg Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Emergency and Critical Care Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama-City, Wakayama 641-8509, Japan. Electronic address:

Objective: The quick sequential organ failure assessment (qSOFA) score is calculated from three variables measured at the scene of trauma-systolic blood pressure, respiratory rate and consciousness. This study aimed to evaluate the discriminative ability of the prehospital qSOFA score for in-hospital mortality in patients with trauma.

Methods: This retrospective multicenter study used data from 42,722 patients with trauma included in a Japanese nationwide trauma registry. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.03.007DOI Listing

Hypoxia/hypercapnia prevents iron-dependent cold injuries in cord blood stem and progenitor cells.

Cytotherapy 2019 Mar 13. Epub 2019 Mar 13.

Etablissement Français du Sang Nouvelle-Aquitaine, Bordeaux, France; Institut national de la santé et de la recherche médicale, University of Bordeaux, France. Electronic address:

Background: Cold-induced cell injuries are associated with an increase in the cellular labile iron pool (LIP) followed by lipid peroxidation and alteration of mitochondrial function, which lead to cell death. Recently, we showed that incubation in a hypoxic/hypercapnic (HH) gas mixture improved the survival of a population of cord blood hematopoietic progenitors and CD34 hematopoietic progenitor and stem cells in severe hypothermia. To explain the underlying mechanism, here we test if this HH-induced cytoprotection in cold conditions is associated with the level of LIP and lysosome stability. Read More

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http://dx.doi.org/10.1016/j.jcyt.2019.02.006DOI Listing

Eye care professionals' perceptions of the benefits of daily disposable silicone hydrogel contact lenses.

Cont Lens Anterior Eye 2019 Mar 13. Epub 2019 Mar 13.

Clinical Research Scientist and Consultant, Berkeley, CA, USA; School of Optometry, University of California, Berkeley. CA, USA. Electronic address:

Purpose: To gain a better understanding of eye care professionals' (ECPs) perceptions regarding the benefits of silicone hydrogel (SiH) daily disposable contact lenses (DDCL), particularly with respect to health, comfort and patient satisfaction.

Methods: A survey was conducted with 300 ECPs in the United States, United Kingdom and Japan during November 2017. The survey comprised 34 statements relating to SiH DDCLs, to which the ECPs provided their level of agreement using a 6 point Likert scale. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.012DOI Listing

Platelet Aggregation and Interleukins Indicators Impacting the Outcomes of Ischemic Stroke.

J Stroke Cerebrovasc Dis 2019 Mar 14. Epub 2019 Mar 14.

Department of Neurology, MedicalCenter 'St. Gregory the Illuminator', Yerevan, Republic of Armenia.

Aim: Relative assessment and relationship between of platelet aggregation and the level of interleukins IL-1β, IL-4, IL-6, and IL-18 among ischemic stroke (IS) patients.

Methods: A prospective clinical cohort study involved 108 IS patients, classified into group 1-surviving (93; 86.1%) and group 2-lethal outcomes (15; 13. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.02.023DOI Listing

Plasma Levels of miR-125b-5p and miR-206 in Acute Ischemic Stroke Patients After Recanalization Treatment: A Prospective Observational Study.

J Stroke Cerebrovasc Dis 2019 Mar 14. Epub 2019 Mar 14.

Department of Neurology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Clinical Research Centre, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Introduction: Multiple microRNAs (miRNAs) participate in the response to hypoxic/ischemic and ischemia-reperfusion events. However, the expression of these miRNAs in circulation from patients with acute ischemic stroke (AIS) receiving recanalization treatment has not been examined, and whether they are associated with the severity and outcome of stroke is still unknown.

Materials And Methods: In this prospective cohort study, plasma levels of miR-125b-5p, miR-15a-3p, miR-15a-5p, and miR-206 were measured at 24hours after thrombolysis with or without endovascular treatment in 94 patients with AIS, as determined by qRT-PCR. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.02.026DOI Listing

Effect of increased dose of total body irradiation on graft failure associated with HLA-haploidentical transplantation in patients with severe haemoglobinopathies: a prospective clinical trial.

Lancet Haematol 2019 Mar 13. Epub 2019 Mar 13.

Hematologic Malignancies and Bone Marrow Transplantation Program, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background: Although severe haemoglobinopathies can be cured with allogeneic blood or bone marrow transplantation, availability of matched donors and toxic effects can be problematic. We previously found that non-myeloablative haploidentical related bone marrow transplantation with post-transplantation cyclophosphamide expanded the donor pool while limiting graft-versus-host disease (GVHD). However, graft failure-albeit with full host haemopoietic recovery-occurred in 50% of patients. Read More

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http://dx.doi.org/10.1016/S2352-3026(19)30031-6DOI Listing

Modified frailty index is an effective risk-stratification tool for patients undergoing total shoulder arthroplasty.

J Shoulder Elbow Surg 2019 Mar 13. Epub 2019 Mar 13.

Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, GA, USA.

Background: Frailty, as quantified by the modified frailty index (mFI), has emerged as a promising method to identify patients at high risk of complications after surgery. Several studies have shown that frailty, as opposed to age, is more predictive of adverse surgical outcomes. We hypothesized that a 5-item mFI could be used to identify patients at elevated risk of complications after total shoulder arthroplasty (TSA). Read More

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http://dx.doi.org/10.1016/j.jse.2018.12.004DOI Listing

Increased perioperative C-reactive protein and decreased postoperative albumin is associated with acute posttraumatic osteomyelitis in patients with high-energy tibial fractures.

Injury 2019 Mar 5. Epub 2019 Mar 5.

Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. Electronic address:

Background: Early diagnosis of acute posttraumatic osteomyelitis (POM) is of vital importance for avoiding devastating complications. Diagnosing POM is difficult due to the lack of a highly specific and sensitive test, such as in myocardial infarct, stroke and intracranial bleeding. Serum inflammatory markers, C-reactive protein (CRP), procalcitonin (PCT), white blood cells (WBC) can support clinical findings but they are not able to differentiate between inflammatory response to infection and the host response to non-infection insult with high specificity and sensitivity. Read More

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http://dx.doi.org/10.1016/j.injury.2019.02.019DOI Listing

Feline herpesvirus vectored-rabies vaccine in cats: A dual protection.

Vaccine 2019 Mar 13. Epub 2019 Mar 13.

Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun, PR China. Electronic address:

In China, cats cause about 5% of human rabies cases. Rabies control in cats plays a role in achieving the ultimate goal of elimination of dog rabies-mediated human deaths. However, there is no cat-specific rabies vaccine in China yet. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.03.008DOI Listing

Leaching and transport of PFAS from aqueous film-forming foam (AFFF) in the unsaturated soil at a firefighting training facility under cold climatic conditions.

J Contam Hydrol 2019 Mar 1. Epub 2019 Mar 1.

Norwegian Geotechnical Institute, Oslo, Norway; Department of Geosciences, University of Oslo, Norway.

The contaminant situation at a Norwegian firefighting training facility (FTF) was investigated 15 years after the use of perfluorooctanesulfonic acid (PFOS) based aqueous film forming foams (AFFF) products had ceased. Detailed mapping of the soil and groundwater at the FTF field site in 2016, revealed high concentrations of per- and polyfluoroalkyl substances (PFAS). PFOS accounted for 96% of the total PFAS concentration in the soil with concentrations ranging from <0. Read More

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http://dx.doi.org/10.1016/j.jconhyd.2019.02.010DOI Listing

Flavored tobacco use is associated with dual and poly tobacco use among adolescents.

Addict Behav 2019 Mar 4. Epub 2019 Mar 4.

University of Cincinnati College of Medicine, Addiction Sciences Division, Department of Psychiatry & Behavioral Neuroscience, Cincinnati, OH, USA.

Objectives: This study examines the relationships between flavored tobacco use and single, dual, and poly tobacco product use, among adolescents. Given the increased use of flavored tobacco products, it is vital to understand if flavored products are associated with dual and poly tobacco product use.

Methods: Data were obtained from the 2017 National Youth Tobacco Survey. Read More

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http://dx.doi.org/10.1016/j.addbeh.2019.02.022DOI Listing

Immune response against subclinical haemonchosis in Himalayan hill goats.

Vet Parasitol 2019 Mar 29;267:47-53. Epub 2019 Jan 29.

Division of Temperate Animal Husbandry, Indian Veterinary Research Institute, Mukteswar Campus, India. Electronic address:

Haemonchosis commonly occurs as chronic and subclinical infection in small ruminants, and understanding of immunological response against subclinical haemonchosis is of paramount importance for designing and implementing effective control strategies. The present study was designed to evaluate immunological response during subclinical haemonchosis, experimentally established in goats. Sixteen 5-6 month-old helminth naive kids were randomly allocated into one of two groups, infected and uninfected; the infected group being infected per os with 250 Haemonchus contortus larvae per kg body weight. Read More

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http://dx.doi.org/10.1016/j.vetpar.2019.01.005DOI Listing

Patent infections with Fasciola hepatica and paramphistomes (Calicophoron daubneyi) in dairy cows and association of fasciolosis with individual milk production and fertility parameters.

Vet Parasitol 2019 Mar 13;267:32-41. Epub 2019 Feb 13.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559 Hannover, Germany. Electronic address:

Infections with the liver fluke Fasciola hepatica may result in considerable economic losses in the dairy livestock industry worldwide. Infections have been associated with detrimental impacts on milk production and milk quality as well as reduced fertility. However, most related data rely on examinations on herd level and the rather few studies on individual cow level are based solely on antibodies as measure for F. Read More

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http://dx.doi.org/10.1016/j.vetpar.2019.01.012DOI Listing

Fulminant Tritrichomonas foetus 'feline genotype' infection in a 3-month old kitten associated with viral co-infection.

Vet Parasitol 2019 Mar 21;267:17-20. Epub 2018 Dec 21.

Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, New South Wales 2006, Australia. Electronic address:

Tritrichomonas foetus is a flagellate protist which commonly causes a waxing and waning large bowel diarrhoea in young cats. We report severe T. foetus infection of the colon, cecum and ileum with concurrent feline enteric coronavirus (FCoV) and feline panleukopenia virus (FPV) in a 3-month-old Bengal kitten with an 8-day history of vomiting, diarrhoea, failure to thrive and coughing. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.12.007DOI Listing
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