994,863 results match your criteria Day Surgery Australia [Journal]


[It can not be healthy not to be ill].

Dtsch Med Wochenschr 2018 Dec 18;143(25):1826-1831. Epub 2018 Dec 18.

This article is written in remembrance of Karl Valentin's 70th anniversary of his death. He was a comedian and song writer suffering from vegetative dystonia and depression lifelong. This hypochondriac developed extreme self observation and had anxiety to get ill permanently. Read More

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http://dx.doi.org/10.1055/a-0649-0274DOI Listing
December 2018

[Posterior reversible encephalopathy syndrome in systemic lupus erythematosus: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Dec;50(6):1102-1107

Department of Rheumatology and Immunology, Peking University First Hospital, Beijing 100034, China.

This case report concerns a 22-year-old woman who had been diagnosed with systemic lupus erythematosus (SLE). She had intermittent fever, butterfly erythema, photosensitivity, oral ulcers, and multiple arthralgia in the past seven years, but she did not adhere to regular treatments. The edema of the lower extremities and face aggravated in the recent two weeks, so she was admitted to our Department of Rheumatology and Clinical Immunology. Read More

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December 2018

[Efficacy and safety of applying ultrasonic osteotome in cervical expansive open-door laminoplasty].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Dec;50(6):1092-1097

Research Center of Clinical Epidemicology, Peking University Third Hospital, Beijing 100191, China.

Objective: To investigate the safety and efficacy of applying ultrasonic osteotome in patients undergoning cervical expansive open-door laminoplasty (CEOL).

Methods: In the study, 94 consecutive patients who were administrated in the spine group of Orthopedic Department of Peking University Third Hospital from March 2015 to March 2016 were reviewed retrospectively. All the patients were diagnosed as multilevel cervical spondylosis myelopathy and underwent CEOL. Read More

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December 2018

[Staining effect of bovine incisors in vitro by tea solutions].

Authors:
M M Zhu Y L Li J Pan

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Dec;50(6):1083-1087

Department of General, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To determine the optimum staining condition of tea solutions on bovine incisors in vitro, by comparing the color stability of tooth surface of different concentrations of tea solutions and methods on bovine incisors in vitro.

Methods: Twenty bovine incisors with color surface A1 were chosen, then randomly divided into 4 groups (n=10). Group 1: soaked with 2% tea solution continuously for 6 days; group 2: soaked with 2% tea solution for 6 days, but changed fresh tea solution everyday; group 3: soaked with 1% tea solution continuously for 6 days; group 4: soaked with 1% tea solution for 6 days but fresh tea solution changed every day. Read More

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December 2018

A case of ileus caused by ileal endometriosis with lymph node involvement.

Int J Surg Case Rep 2018 Dec 12;54:90-94. Epub 2018 Dec 12.

Department of Gastroenterological Surgery, Hiroshima Prefectural Hospital, Japan; Department of Gastroenterological and Transplant Surgery Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Japan.

Introduction: Endometriosis is characterized by the presence of endometrial tissue outside the uterus. However, the presence of endometriotic lesions in extrauterine locations at the terminal ileum is unusual and a preoperative diagnosis of intestinal endometriosis has proved challenging.

Presentation Of Case: A 49-year-old woman visited a local hospital complaining chiefly of vomiting. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.066DOI Listing
December 2018

Post-learning stress reduces the misinformation effect: effects of psychosocial stress on memory updating.

Psychoneuroendocrinology 2018 Dec 10;102:164-171. Epub 2018 Dec 10.

Department of Psychology, McGill University, Avenue McGill College 2001, H3A 1G1 Montreal, Canada.

Episodic memories can be modified when exposed to new and related information. This phenomenon, known as memory updating, is generally thought to be adaptive but can also lead to incorporating false information into a memory trace. Given the well-known effects of stress on episodic memory, we used a false information paradigm to investigate if acute stress during memory updating (i. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2018.12.008DOI Listing
December 2018

Combined effects of aging and low temperature, long time heating on pork toughness.

Meat Sci 2018 Dec 5;150:33-39. Epub 2018 Dec 5.

National Engineering Research Center of Seafood, Ganjingzi #1, 116304 Dalian, Liaoning, China; Department of Agricultural and Biosystems Engineering, Iowa State University, Ames, IA 50011, USA.

The combined effects of aging and low temperature, long time heating (LTLT) on meat toughness were investigated. Pork loins were heated at 53 or 58 °C for up to 20 h, and shear force values, cooking loss, moisture content, collagen solubility, electrophoresis of myofibrillar proteins were determined. Structural changes in perimysium were also observed by light microscopy and scanning electron microscopy (SEM). Read More

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http://dx.doi.org/10.1016/j.meatsci.2018.12.001DOI Listing
December 2018

Training and transfer effects of prospective memory training in 13- to 15-year-old children.

J Exp Child Psychol 2018 Dec 15;179:227-247. Epub 2018 Dec 15.

Donders Institute for Brain, Cognition and Behaviour, Centre for Cognition, Radboud University, 6500 HE Nijmegen, the Netherlands. Electronic address:

Prospective memory (PM) plays a crucial role in children's academic achievement and interpersonal relationships. However, there is a lack of studies exploring training and transfer effects of process-based PM training in healthy young adolescents. In the current study, 13- to 15-year-old children participated in an 8-day PM training program using the Virtual Week computer game. Read More

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http://dx.doi.org/10.1016/j.jecp.2018.11.014DOI Listing
December 2018

Rapid Acquisition of Cytomegalovirus-Specific T Cells with a Differentiated Phenotype, in Non-Viremic Hematopoietic Stem Transplant Recipients Vaccinated with CMVPepVax.

Biol Blood Marrow Transplant 2018 Dec 15. Epub 2018 Dec 15.

Department of Experimental Therapeutics, and. Electronic address:

Early cytomegalovirus (CMV) reactivation remains a significant cause of morbidity and mortality in allogeneic hematopoietic cell transplant (HCT) recipients. CMVPepVax is an investigational peptide vaccine designed to control CMV infection in HCT patients seropositive for CMV by stimulating the expansion of T cell subsets that target the CMV tegument protein pp65. In a randomized Phase 1b pilot trial (NCT01588015), two injections of CMVPepVax (at days 28 and 56 post-HCT) demonstrated safety, immunogenicity, increased relapse-free survival, and reduced CMV reactivation and usage of antivirals. Read More

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http://dx.doi.org/10.1016/j.bbmt.2018.12.070DOI Listing
December 2018

Declines in motor transfer following upper extremity task-specific training in older adults.

Exp Gerontol 2018 Dec 15. Epub 2018 Dec 15.

University of Utah, 50 N. Medical Dr., Salt Lake City, UT 84112, USA; School of Biological and Health Systems Engineering, 501 E. Tyler Mall, ECG 334A, Arizona State University, Tempe, AZ 85287, USA. Electronic address:

Background: Age-related declines in function can limit older adults' independence with activities of daily living (ADLs). While task-specific training maybe a viable approach to improve function, limited clinical resources prevent extensive training on wide ranges of skills and contexts. Thus, training on one task for the benefit of another (i. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S05315565183060
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http://dx.doi.org/10.1016/j.exger.2018.12.012DOI Listing
December 2018
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Differential replication efficiencies between Japanese encephalitis virus genotype I and III in avian cultured cells and young domestic ducklings.

PLoS Negl Trop Dis 2018 Dec 18;12(12):e0007046. Epub 2018 Dec 18.

Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, PR China.

Japanese encephalitis virus (JEV) genotype dominance has shifted to genotype I (GI) from genotype III (GIII) in China as demonstrated by molecular epidemiological surveillance. In this study, we performed a serological survey in JEV-non-vaccinated pigs to confirm JEV genotype shift at the sero-epidemiological level. The average ratio of GI/GIII infection was 1. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007046DOI Listing
December 2018

Effectiveness of a text-messaging-based smoking cessation intervention ("Happy Quit") for smoking cessation in China: A randomized controlled trial.

PLoS Med 2018 Dec 18;15(12):e1002713. Epub 2018 Dec 18.

Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, China.

Background: China has the highest global prevalence of cigarette smokers, accounting for more than 40% of the total cigarette consumption in the world. Considering the shortage of smoking cessation services in China, and the acceptability, feasibility, and efficacy of mobile-phone-based text messaging interventions for quitting smoking in other countries, we conducted a mobile-phone-based smoking cessation study in China.

Methods And Findings: We conducted a randomized controlled trial in China across 30 cities and provinces from August 17, 2016, to May 27, 2017. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002713DOI Listing
December 2018

Prepare for More Antibiotics: Commentary on an article by Avinash Inabathula, MD, et al.: "Extended Oral Antibiotic Prophylaxis in High-Risk Patients Substantially Reduces Primary Total Hip and Knee Arthroplasty 90-Day Infection Rate".

Authors:
Monti Khatod

J Bone Joint Surg Am 2018 Dec;100(24):e155

Department of Orthopaedic Surgery, Kaiser Permanente West Los Angeles Medical Center, Los Angeles, California.

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http://dx.doi.org/10.2106/JBJS.18.00932DOI Listing
December 2018

The Association of Body Mass Index with Risk of Long-Term Revision and 90-Day Mortality Following Primary Total Hip Replacement: Findings from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

J Bone Joint Surg Am 2018 Dec;100(24):2140-2152

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Background: The influence of obesity on outcomes following total hip replacement is unclear. Restriction of total hip replacement on the basis of body mass index (BMI) has been suggested. The purpose of this study was to assess the influence of BMI on the risk of revision and 90-day mortality. Read More

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http://dx.doi.org/10.2106/JBJS.18.00120DOI Listing
December 2018

Extended Oral Antibiotic Prophylaxis in High-Risk Patients Substantially Reduces Primary Total Hip and Knee Arthroplasty 90-Day Infection Rate.

J Bone Joint Surg Am 2018 Dec;100(24):2103-2109

Indiana University Health Orthopedics, Indianapolis, Indiana.

Background: Total joint arthroplasty (TJA) episodic payment models shift risk and cost of periprosthetic joint infection (PJI) to surgeons and hospitals, causing some to avoid treating high-risk patients. Furthermore, there are little data to support optimization of host factors preoperatively to decrease PJI, and recent literature supports using extended antibiotic prophylaxis following reimplantation TJA. The purpose of this study was to evaluate whether extended oral antibiotic prophylaxis minimized PJI after primary TJA in high-risk patients. Read More

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http://dx.doi.org/10.2106/JBJS.17.01485DOI Listing
December 2018

Malignant and Benign Phenotypes of Multimorbidity in Heart Failure: Implications for Clinical Practice.

J Cardiovasc Nurs 2018 Dec 17. Epub 2018 Dec 17.

Lei Chen, PhD Research Fellow, Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne. Yih-Kai Chan, PhD Research Fellow, Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne. Lucy Busija, PhD Senior Research Fellow, Institute for Health and Ageing, Australian Catholic University, Melbourne. Tone M. Norekval, PhD Professor, Department of Heart Disease, Haukeland University Hospital; and Department of Clinical Science, University of Bergen, Bergen, Norway. Barbara Riegel, PhD Professor, Biobehavioral Health Sciences Department, School of Nursing, University of Pennsylvania, Philadelphia. Simon Stewart, PhD Professor, Cardiology Unit, The Queen Elizabeth Hospital, Adelaide, Australia.

Background: The impact of different patterns of multimorbidity in heart failure (HF) on health outcomes is unknown.

Objectives: The aim of this study was to test the hypothesis that, independent of the extent of comorbidity, there are distinctive phenotypes of multimorbidity that convey an increased risk for premature mortality in patients hospitalized with HF.

Methods: We analyzed the clinical profile and health outcomes of 787 patients hospitalized with HF participating in a multidisciplinary HF management program with a minimum 12-month follow-up. Read More

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http://dx.doi.org/10.1097/JCN.0000000000000557DOI Listing
December 2018

A Randomized Trial to Evaluate the Effect of Toric Versus Spherical Contact Lenses on Vision and Eyestrain.

Eye Contact Lens 2019 Jan;45(1):28-33

The Ocular Surface Institute (D.A.B., D.R.P.), University of Houston College of Optometry, Houston, TX; University of Alabama at Birmingham School of Optometry (S.M.C., J.J.N.), Birmingham, AL; The Ohio State University College of Optometry (K.M.B.), Columbus, OH; Alcon Laboratories (J.H.M.), Fort Worth, TX; Department of Biomedical Engineering (S.H.S.), University of Rochester, Rochester, NY; and Johnson & Johnson Vision Care, Inc (B.K.L., K.O.L.), Jacksonville, FL.

Objectives: To compare the effect of toric versus spherical soft contact lenses on objective measures of visual performance using visual acuity and electromyography of the orbicularis oculi muscle.

Methods: Current soft contact lens wearers with -0.75 to -1. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000528DOI Listing
January 2019

The Bundled Payment Initiative for Hip Fracture Arthroplasty Patients: One Institution's Experience.

J Orthop Trauma 2018 Dec 11. Epub 2018 Dec 11.

NYU Langone Orthopedic Hospital, NYU Langone Medical Center, New York, New York, USA Investigation performed at NYU Langone Medical Center, New York, NY, USA This manuscript was presented as a poster presentation at Orthopaedic Trauma Association Annual Meeting 2017 in Vancouver, BC, Canada and at the American Academy of Orthopedic Surgeons Annual Meeting 2018 in New Orleans, LA.

Objectives: Analyze the effectiveness of a BPCI (Bundle Payments for Care Improvement) initiative at a large urban medical center for hip fracture patients included in the bundle payment program with respect to improving patient outcomes and reducing cost DESIGN:: Retrospective cohort SETTING:: Single Academic Institution PATIENTS/PARTICIPANTS:: Patients discharged with the DRG codes 469-470 performed for hip fractures between July 2011 and September 2014 were evaluated. A BPCI initiative focused on optimizing care coordination, patient education, expectations, and minimizing post-acute facility and resource utilization was initiated in October 2013. Patient outcomes prior to the introduction of the BPCI initiative were compared to those who participated in the initiative. Read More

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http://dx.doi.org/10.1097/BOT.0000000000001378DOI Listing
December 2018

Changes in Cognitive Function Scores After Cerebrospinal Fluid Tap Testing in Patients with Suspected Idiopathic Normal-Pressure Hydrocephalus.

Cogn Behav Neurol 2018 Dec;31(4):201-206

Neurosurgery.

Background: In patients suspected of having idiopathic normal-pressure hydrocephalus (iNPH), improvement in impaired cognition is common after a diagnostic cerebrospinal fluid tap test (CSFTT). Measures used to evaluate cognitive function before and after a CSFTT include the Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), and Trail Making Test (TMT). However, the time point at which cognitive function should be reevaluated after a CSFTT remains controversial. Read More

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http://dx.doi.org/10.1097/WNN.0000000000000176DOI Listing
December 2018

Fast-track Radioiodine Ablation Therapy After Thyroidectomy Reduces Sick Leave in Patients With Differentiated Thyroid Cancer (FASTHYNA Trial).

Clin Nucl Med 2018 Dec 17. Epub 2018 Dec 17.

From the Department of Surgery and.

Background: Recombinant human thyroid stimulating hormone (RhTSH) aided radioiodine ablative therapy (RIT) is current-day practice in the treatment of differentiated thyroid cancer (DTC). It is often planned 4 to 6 weeks after surgery or sometimes even longer (standard protocol). The RhTSH-aided RIT, however, has the advantage that it can be planned shortly after thyroidectomy. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002420DOI Listing
December 2018

Neonatal Death Caused by Interrupted Aortic Arch Associated With 22q11.2 Deletion Syndrome: An Autopsy Case Report.

Am J Forensic Med Pathol 2018 Dec 17. Epub 2018 Dec 17.

Division of Genomic Medicine, Kanazawa Medical University, Ishikawa, Japan.

A case of clinically unsuspected fatal interrupted aortic arch (IAA) is described. A 17-day-old Japanese girl unexpectedly entered respiratory arrest at home. On autopsy, the heart was hypertrophic, with no apparent connection between the ascending and descending aortas. Read More

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http://dx.doi.org/10.1097/PAF.0000000000000454DOI Listing
December 2018

In Vivo Effectiveness of Injectable Antibiotics on the Recovery of Acute Actinobacillus pleuropneumoniae-Infected Pigs.

Microb Drug Resist 2018 Dec 18. Epub 2018 Dec 18.

1 Clinic of Medicine, Faculty of Veterinary Medicine, School of Health Sciences, University of Thessaly, Karditsa, Greece.

The aim of this trial was to evaluate the in vivo effectiveness of injectable antibiotics of one- or two-dose administration on recovery of acute App (Actinobacillus pleuropneumoniae)-infected pigs. Ninety pigs with moderate general clinical score (GCS) of a commercial farm, suffering from acute App infection, were divided in two groups: (a) T1: one administration of gamithromycin injectable solution and (b) T2: two administrations of florfenicol injectable solution. Morbidity/mortality, clinical scores (clinical appearance score index-CAS, clinical respiratory score-CRS, clinical cough score index [CCS], general respiratory clinical score-GCRS, and general clinical score-GCS), body temperature score (BTS), and posttreatment interval were recorded. Read More

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http://dx.doi.org/10.1089/mdr.2018.0277DOI Listing
December 2018

Association of High Mobility Group Box Protein B1 Gene Polymorphisms with Pneumonia Susceptibility and Severity.

Genet Test Mol Biomarkers 2018 Dec 18. Epub 2018 Dec 18.

2 Department of Intensive Care Unit, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Objective: To investigate the relationship between the high mobility group box protein B1 (HMGB1) single nucleotide polymorphisms (SNPs) rs1412125, rs2249825, and rs1045411 with pneumonia in terms of susceptibility, severity, and inflammatory response.

Methods: The genotypes of HMGB1 rs1412125 (-1615T > C), rs2249825 (3814C > G), and rs1045411 (2262C > T) loci in 328 patients with community-acquired pneumonia (CAP) and 317 healthy subjects were analyzed by Sanger sequencing. The expression and secretion of the inflammatory cytokines HMGB1, interleukin (IL)-10, tumor necrosis factor-alpha (TNF-α), and IL-6 were determined after lipopolysaccharide (LPS) stimulation of peripheral whole blood cells. Read More

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http://dx.doi.org/10.1089/gtmb.2018.0174DOI Listing
December 2018

Effect of Extremely Low Frequency Electromagnetic Fields on Expression of T-bet and GATA-3 Genes and Serum Interferon-γ and Interleukin-4.

J Interferon Cytokine Res 2018 Dec 18. Epub 2018 Dec 18.

1 Department of Immunology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran .

This study investigated the effect of various magnetic flux densities of extremely low frequency electromagnetic fields (ELF-EMF) on expression of T-box transcription factor (T-bet) and GATA binding protein-3 (GATA-3) genes in the spleen and thymus of rats injected with human serum albumin (HSA). Moreover, serum levels of interferon (IFN)-γ and interleukin (IL)-4 were evaluated at two phases, that is, prestimulation and poststimulation with HSA. Eighty rats were separated into five groups, and four groups were exposed daily to 50 Hz EMF of 1, 100, 500, and 2000 μT magnetic flux densities for 60 days. Read More

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http://dx.doi.org/10.1089/jir.2018.0105DOI Listing
December 2018

Profiling Hospital Performance Based on Mortality After Transcatheter Aortic Valve Replacement in Ontario, Canada.

Circ Cardiovasc Qual Outcomes 2018 Dec;11(12):e004947

Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada (G.E.-G., D.T.K., H.C.W.).

Background: Public reporting of hospital-level outcomes is increasingly common as a means to target quality improvement strategies to ensure the delivery of optimal care. Despite the rapid dissemination of transcatheter aortic valve replacement (TAVR), there is a paucity of reliable case-mix adjustment models for hospital profiling in TAVR. Our objective was to develop and evaluate different models for calculating risk-standardized all-cause mortality rates (RSMRs) post-TAVR. Read More

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004947DOI Listing
December 2018

The response of colonic mucosa-associated microbiota composition, mucosal immune homeostasis, and barrier function to early-life galactooligosaccharides intervention in suckling piglets.

J Agric Food Chem 2018 Dec 18. Epub 2018 Dec 18.

Suckling piglets were used to investigate the response of colonic mucosa-associated microbiota composition, mucosal immune homeostasis, and barrier function to early-life galactooligosaccharides (GOS) intervention. 10 mL 1 g/kg body weight GOS solutions and physiological saline solutions were fed the newborn piglets in GOS group and in the control (CON) group a week time, respectively. Six piglets from each group were euthanized on the day 8 and day 21. Read More

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http://dx.doi.org/10.1021/acs.jafc.8b05679DOI Listing
December 2018

Improved isotopic model based on N tracing and Rayleigh-type isotope fractionation for simulating differential sources of N O emissions in a clay grassland soil.

Rapid Commun Mass Spectrom 2018 Dec 18. Epub 2018 Dec 18.

Rothamsted Research, North Wyke, Okehampton, Devon, EX20 2SB, UK.

Rationale: Isotopic signatures of N O can help distinguish between two sources (fertiliser N, or endogenous soil N) of N O emissions. The contribution of each source to N O emissions after N-application is difficult to determine. Here, isotopologue signatures of emitted N O are used in an improved isotopic model based on Rayleigh type equations. Read More

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http://dx.doi.org/10.1002/rcm.8374DOI Listing
December 2018

Entrainment memories: What does stable mean?

Authors:
Manfred Gödel

Psych J 2018 Dec;7(4):209-224

Institute of Medical Psychology, Ludwig Maximilian University, Munich, Germany.

Diurnal environmental factors (zeitgebers) set the circadian clock in an antagonistic way: The body clock is tuned forward in the morning, while the same factor late in the day puts the body clock back to a later time-point: Morning light, for example, reduces the clock-effective light-reception (zeitnehmer ) by shifting the expression of the circadian, light-processing, molecular machinery more into the late, light-less night. Evening light does the same by a backward-shift, respectively. The balance between these daily back and forth adaptations results in a synchronization of the organismic timing with its environment. Read More

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http://dx.doi.org/10.1002/pchj.264DOI Listing
December 2018

Role of Virtual Touch Tissue Imaging Quantification in the Assessment of Hepatic Sinusoidal Obstruction Syndrome in a Rat Model.

J Ultrasound Med 2018 Dec 17. Epub 2018 Dec 17.

Departments of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Objectives: To investigate the value of liver stiffness in rats with various degrees of hepatic sinusoidal obstruction syndrome (HSOS) induced by monocrotaline by comparing liver histopathologic findings.

Methods: Seventy rats were randomly divided into a control group (n = 10), a low-dose monocrotaline group (n = 30), and a high-dose monocrotaline group (n = 30). After successful modeling, the liver shear wave velocity (SWV) by Virtual Touch tissue imaging quantification (Siemens Medical Solutions, Mountain View, CA) and the alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin levels of the groups were obtained on days 3 and 5, and the intergroup differences were compared. Read More

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http://dx.doi.org/10.1002/jum.14893DOI Listing
December 2018

Predicting Low-Risk for Sustained Alcohol Use After Early Liver Transplant for Acute Alcoholic Hepatitis: The SALT Score.

Hepatology 2018 Dec 18. Epub 2018 Dec 18.

Department of Gastroenterology, University of California, San Francisco, San Francisco, CA, USA.

Early liver transplant (LT) for alcohol-associated disease (i.e. without a specific sobriety period) is controversial, but increasingly used. Read More

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http://dx.doi.org/10.1002/hep.30478DOI Listing
December 2018

A phase 2 trial of regorafenib as a single agent in patients with chemotherapy-refractory, advanced, and metastatic biliary tract adenocarcinoma.

Cancer 2018 Dec 18. Epub 2018 Dec 18.

National Institute for Occupational Safety and Health (NIOSH) Research Branch, Centers for Disease Control and Prevention, Pittsburgh, Pennsylvania.

Background: Biliary tract cancers are rare, aggressive neoplasms. Most patients present with advanced/unresectable or metastatic disease at diagnosis, and no second-line regimen has demonstrated clinical benefit. This was a phase 2 study evaluating the efficacy and safety of regorafenib in patients who had advanced/unresectable or metastatic disease after receiving standard therapy. Read More

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http://dx.doi.org/10.1002/cncr.31872DOI Listing
December 2018

Reduction of PGRN increased fibrosis during skin wound healing in mice.

Histol Histopathol 2018 Dec 18:18076. Epub 2018 Dec 18.

Department of Forensic Medicine, Xuzhou Medical University; Xuzhou, Jiangsu, P.R. China.

Progranulin (PGRN) is a multi-functional growth factor known to be involved in regulating of development, cell cycle progression, cell motility, tumorigenesis and angiogenesis. Research has revealed that PGRN is a crucial mediator of skin wound healing. Nonetheless, the role of PGRN in the fibrosis process of cutaneous wound healing has not been identified. Read More

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http://dx.doi.org/10.14670/HH-18-076DOI Listing
December 2018

Slow wave activity surrounding stage N2 K-complexes and daytime function measured by psychomotor vigilance test in obstructive sleep apnea.

Sleep 2018 Dec 17. Epub 2018 Dec 17.

Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Study Objective: To better understand the inter-individual differences in neurobehavioral impairment in obstructive sleep apnea (OSA) and its treatment with continuous positive airway pressure (CPAP), we examined how changes in sleep electroencephalography (EEG) slow waves were associated with next-day psychomotor vigilance test (PVT) lapses.

Methods: Data from 28 OSA subjects (AHI3A>15/hr.; AHI3A=sum of all apneas and hypopneas with 3% O2 desaturation and/or an EEG arousal, divided by total sleep time [TST]) who underwent three full in-lab nocturnal polysomnographies (NPSGs: chronic OSA, CPAP-treated OSA, and acute OSA), and 19 healthy-sleepers were assessed. Read More

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http://dx.doi.org/10.1093/sleep/zsy256DOI Listing
December 2018

Combat exposure, post-traumatic stress symptoms, and health-related behaviors: The role of sleep continuity and duration.

Sleep 2018 Dec 17. Epub 2018 Dec 17.

Walter Reed Army Institute of Research.

Study Objectives: Aggression, substance misuse, and other health risk behaviors are common among combat veterans. We examined whether sleep quality and quantity predict the association between combat exposure, post-traumatic stress symptoms, and adverse health-related behaviors.

Methods: Soldiers (N= 2420) from a brigade combat team completed surveys assessing combat experiences, and psychological and behavioral health factors, approximately three months following deployment to Afghanistan in 2011. Read More

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http://dx.doi.org/10.1093/sleep/zsy257DOI Listing
December 2018

Comparative efficacy of commercial inactivated Newcastle disease virus vaccines against Newcastle disease virus genotype VII in broiler chickens.

Poult Sci 2018 Dec 15. Epub 2018 Dec 15.

Department of Animal Production, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.

Newcastle disease is still causing huge economic losses and devastating outbreaks in poultry flocks despite implementation of extensive vaccination programs. Five commercial broiler chicken groups were established as G1 (non-vaccinated, non-challenged group) and G2 (non-vaccinated, challenged group), and 3 vaccinated challenged groups as G3 (vaccinated with heterologous inactivated Newcastle disease virus (NDV) genotype II (NDV II) vaccine), G4 (vaccinated with homologous inactivated NDV genotype VII (NDV VII) vaccine), and G5 (vaccinated with bivalent (heterologous inactivated NDV II plus H5) vaccine) were used. Challenge test was done using a velogenic NDV genotype VII (vNDV VII) at 28-d olds. Read More

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http://dx.doi.org/10.3382/ps/pey559DOI Listing
December 2018

Effects of organophosphate ester flame retardants on endochondral ossification in ex vivo murine limb bud cultures.

Toxicol Sci 2018 Dec 18. Epub 2018 Dec 18.

McGill University, Department of Pharmacology & Therapeutics, Montreal, Quebec, Canada.

Phasing out the usage of polybrominated diphenyl ether (PBDE) flame retardants (FRs) in consumer products led to their widespread replacement with organophosphate ester (OPE) FRs, despite scarce safety data. PBDE exposures were associated with the suppression of endochondral ossification but little is known about the effects of OPEs on bones. Here, we used a novel ex vivo murine limb bud culture system to compare the effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) with those of several OPEs. Read More

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http://dx.doi.org/10.1093/toxsci/kfy301DOI Listing
December 2018
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The Feasibility and Efficacy of Ultrasound-Guided C2 Nerve Root Coblation for Cervicogenic Headache.

Pain Med 2018 Dec 17. Epub 2018 Dec 17.

Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Objective: The cervicogenic headache is a syndrome caused by dysfunction of the upper cervical spine and its component bony, disc, and/or soft tissue elements. The C2 nerve root may play a pivotal role in cervicogenic headache. In this retrospective study, we evaluated the feasibility and efficacy of ultrasound-guided C2 nerve root coblation in managing 26 patients with cervicogenic headache. Read More

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http://dx.doi.org/10.1093/pm/pny227DOI Listing
December 2018

Epidural analgesia after minimally invasive esophagectomy: efficacy and complication profile.

Dis Esophagus 2018 Dec 17. Epub 2018 Dec 17.

Department of Surgery, University Medical Center Utrecht, The Netherlands.

Adequate postoperative pain management is essential to facilitate uneventful recovery after esophagectomy. Although epidural analgesia is the gold standard, it is not satisfactory in all patients. The aim of this study is to describe the efficacy and complication profile of epidural analgesia after minimally invasive esophagectomy (MIE). Read More

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http://dx.doi.org/10.1093/dote/doy116DOI Listing
December 2018

Spirituality among People with Disabilities: A Nationally Representative Study of Spiritual and Religious Profiles.

Health Soc Work 2018 Dec 15. Epub 2018 Dec 15.

David R. Hodge, PhD, is professor, School of Social Work, Arizona State University, Phoenix, and senior nonresident fellow, Program for Research on Religion and Urban Civil Society, University of Pennsylvania, Philadelphia. Conroy Reynolds, PhD, BCC, MFT Associate, is senior clinical professor, Department of Counseling and Human Development, School of Education, University of Redlands, Redlands, CA.

This study examined the relationship between eight dimensions of spirituality (and religion) and people with four different types of disability status: hearing, vision, physical mobility, and emotional or mental disabilities. The overarching aim was to identify specific spiritual-religious profiles within each disability population relative to the general population. To conduct this cross-sectional examination, the authors used nationally representative data from the General Social Survey in the United States. Read More

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http://dx.doi.org/10.1093/hsw/hly035DOI Listing
December 2018

Transcriptome alterations in myotonic dystrophy skeletal muscle and heart.

Hum Mol Genet 2018 Dec 17. Epub 2018 Dec 17.

Dept. of Biology, Massachusetts Institute of Technology.

Myotonic dystrophy (dystrophia myotonica, DM) is a multi-systemic disease caused by expanded CTG or CCTG microsatellite repeats. Characterized by symptoms in muscle, heart, and central nervous system, among others, it is one of the most variable diseases known. A major pathogenic event in DM is the sequestration of Muscleblind-like proteins by CUG or CCUG repeat-containing RNAs transcribed from expanded repeats, and differences in the extent of MBNL sequestration dependent on repeat length and expression level may account for some portion of the variability. Read More

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http://dx.doi.org/10.1093/hmg/ddy432DOI Listing
December 2018

The establishment of a mouse model of deep endometriosis.

Hum Reprod 2018 Dec 15. Epub 2018 Dec 15.

Shanghai OB/GYN Hospital, Fudan University, Shanghai, China.

Study Question: Is it possible to establish a mouse model of deep endometriosis (DE)?

Summary Answer: A mouse DE model that is macroscopically and microscopically similar to nodular lesions in humans can be constructed in as short as 3 weeks by intraperitoneal injection of uterine fragments along with the infusion of substance P (SP) and/or calcitonin gene-related peptide (CGRP).

What Is Known Already: Although a baboon DE model was reported 5 years ago, its prohibitive cost and demand for facilities and expertise associated with the use of non-human primates put its use out of reach for most laboratories.

Study Design, Size, Duration: A total of 48 female Balb/C mice were used for this study. Read More

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http://dx.doi.org/10.1093/humrep/dey361DOI Listing
December 2018

Noma-knowledge and practice competence among primary healthcare workers: a cross-sectional study in Burkina Faso.

Int Health 2018 Dec 18. Epub 2018 Dec 18.

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

Background: Noma is a quickly progressing, neglected opportunistic infection. It starts in the mouth as an oral lesion but can relatively quickly develop into extensive facial destruction and lead to death if not treated in time. This study aims to shed light on primary healthcare workers' practice competences in working with and knowledge of noma. Read More

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http://dx.doi.org/10.1093/inthealth/ihy088DOI Listing
December 2018

Improved oral hygiene care attenuates the cardiovascular risk of oral health disease: a population-based study from Korea.

Eur Heart J 2018 Dec 18. Epub 2018 Dec 18.

Cardiovascular Center, Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 13620, Korea.

Aims: Oral health problems such as periodontal disease, dental caries, and tooth loss have been suggested to have associations with cardiovascular disease. This study aimed to evaluate whether oral hygiene behaviour can alleviate cardiovascular risk associated with oral health status using a nationwide population-based cohort.

Methods And Results: The data of 247 696 healthy adults aged 40 years or older who underwent an oral health screening programme and had no history of major cardiovascular events were extracted from the National Health Insurance System-National Health Screening Cohort. Read More

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http://dx.doi.org/10.1093/eurheartj/ehy836DOI Listing
December 2018

Household food unavailability due to financial constraints affects the nutrient intake of children.

Authors:
Hitomi Suga

Eur J Public Health 2018 Dec 15. Epub 2018 Dec 15.

Department of Social and Preventive Epidemiology, School of Public Health, The University of Tokyo, Tokyo, Japan.

Background: A household's food unavailability due to financial constraints may act as a barrier to a healthy diet for children. This cross-sectional study aimed to examine the association between food unavailability due to financial constraints and the nutrient intake of children aged 1-15 years using data of a nationwide survey among the Japanese population.

Methods: Datasets from the National Health and Nutrition Survey and the Comprehensive Survey of Living Conditions in Japan, 2014 were used for this study. Read More

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http://dx.doi.org/10.1093/eurpub/cky263DOI Listing
December 2018

Intraoperative pyloric botulinum toxin injection during Ivor-Lewis gastroesophagectomy to prevent delayed gastric emptying.

Dis Esophagus 2018 Dec 17. Epub 2018 Dec 17.

Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom.

Delayed gastric emptying (DGE) is a common morbidity that affects 10%-50% of Ivor-Lewis gastroesophagectomy (ILGO) patients. DGE management is variable with no gold standard prevention or treatment. We conducted a study to assess the effectiveness of intraoperative pyloric botulinum toxin injection in preventing DGE. Read More

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http://dx.doi.org/10.1093/dote/doy112DOI Listing
December 2018

Propensity score-matched analysis of coronary artery bypass grafting versus second-generation drug-eluting stents for triple-vessel disease.

Eur J Cardiothorac Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.

Objectives: This study aimed to compare the mid-term results of coronary artery bypass grafting (CABG) with those of percutaneous coronary intervention (PCI) with second-generation drug-eluting stents (DESs) for triple-vessel disease.

Methods: Between February 2010 and December 2015, 607 patients underwent primary isolated CABG and 264 patients underwent PCI with second-generation DESs (everolimus-eluting stent, biolimus-eluting stent or zotarolimus-eluting stent) for triple-vessel disease with or without left main disease. We compared the CABG group with the second-generation DES group using propensity score matching analysis. Read More

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http://dx.doi.org/10.1093/ejcts/ezy415DOI Listing
December 2018

What is the role for metronidazole in the treatment of Clostridium difficile infection? Results from a national cohort study of Veterans with initial mild disease.

Clin Infect Dis 2018 Dec 18. Epub 2018 Dec 18.

Infectious Diseases Research Program, Providence Veterans Affairs Medical Center, Providence, RI, United States.

Background: Metronidazole may still be an appropriate therapeutic option for mild Clostridium difficile infection (CDI) in select patients, but data is limited to guide clinicians in identifying these patients.

Methods: Our two-stage study included a national cohort of Veterans with a first episode of mild CDI (2010-2014). First, among those treated with metronidazole, we identified predictors of success, defined as absence of all-cause mortality or recurrence 30-days post-treatment, using multivariable unconditional logistic regression. Read More

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http://dx.doi.org/10.1093/cid/ciy1077DOI Listing
December 2018

Left Ventricular Strain Is Abnormal in Preclinical and Overt Hypertrophic Cardiomyopathy: Cardiac MR Feature Tracking.

Radiology 2018 Dec 18:180339. Epub 2018 Dec 18.

From the Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Md (D.M.V., M.W.T.); Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, England (D.M.V., M.W.T., J.A.N.); Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Mass (D.M.V.); Division of Cardiology (E.Y.) and Russell H. Morgan Department of Radiology and Radiological Science (L.C.), Johns Hopkins Hospital, Baltimore, Md; University of Chicago, The College, Chicago, Ill (P.J.J.); Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio (M.W.T.); Cardiovascular Division, Brigham and Women's Hospital, Boston, Mass (H.F., C.Y.H.); Departments of Internal Medicine and Pediatrics, University of Michigan, Ann Arbor, Mich (S.M.D., M.W.R.); Department of Cardiology, Boston Children's Hospital, Boston, Mass (S.D.C.); The Heart Institute and Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.T.);New York University Langone Medical Center, New York, NY (M.V.S.); Department of Pediatrics, Washington University School of Medicine, St Louis, Mo (C.E.C.); Department of Nursing, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, Mass (L.S.); and School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Ave, Madison, WI 53792 (D.A.B.).

Purpose To evaluate myocardial strain and circumferential transmural strain difference (cTSD; the difference between epicardial and endocardial circumferential strain) in a genotyped cohort with hypertrophic cardiomyopathy (HCM) and to explore correlations between cTSD and other anatomic and functional markers of disease status. Left ventricular (LV) dysfunction may indicate early disease in preclinical HCM (sarcomere mutation carriers without LV hypertrophy). Cardiac MRI feature tracking may be used to evaluate myocardial strain in carriers of HCM sarcomere mutation. Read More

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http://dx.doi.org/10.1148/radiol.2018180339DOI Listing
December 2018

High-Sensitivity Troponin I in Hospitalized and Ambulatory Patients With Heart Failure With Preserved Ejection Fraction: Insights From the Heart Failure Clinical Research Network.

J Am Heart Assoc 2018 Dec;7(24):e010364

1 Duke Clinical Research Institute and Division of Cardiology Duke University Medical Center Durham NC.

Background We sought to study the prevalence of high-sensitivity troponin and its association with cardiac structure and outcomes in ambulatory and hospitalized patients with heart failure with a preserved ejection fraction ( HF p EF ). Methods and Results A post hoc analysis utilized data from HF p EF patients: DOSE (Diuretic Optimization Strategies Evaluation) and CARRESS - HF (Cardiorenal Rescue Study in Acute Decompensated Heart Failure) enrolled patients hospitalized with acute HF p EF , and RELAX (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Heart Failure With Preserved Ejection Fraction) enrolled ambulatory patients with HF p EF . High-sensitivity troponin I (hs-TnI) was measured in hospitalized patients at baseline, at 72 to 96 hours, on day 7, and on day 60. Read More

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http://dx.doi.org/10.1161/JAHA.118.010364DOI Listing
December 2018

Trevo 2000: Results of a Large Real-World Registry for Stent Retriever for Acute Ischemic Stroke.

J Am Heart Assoc 2018 Dec;7(24):e010867

1 Department of Neurosciences Drexel Neurosciences Institute Philadelphia PA.

Background Recent randomized controlled trials show benefit of thrombectomy for large vessel occlusion in stroke. Real-world data aid in assessing reproducibility of outcomes outside of clinical trials. The Trevo Retriever Registry is a multicenter, international, prospective study designed to assess outcomes in a large cohort of patients. Read More

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http://dx.doi.org/10.1161/JAHA.118.010867DOI Listing
December 2018
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