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Ear Nose Throat J 2022 Jun 21:1455613221104438. Epub 2022 Jun 21.

Department of Ophthalmology, 58934Korea University College of Medicine, Guro Hospital, Seoul, South Korea.

The purpose of this study was to investigate whether the use of hyaluronic acid/collagen resorbable gel (Regenwel) has an inhibitory effect on rhinostomy obstruction during endoscopic dacryocystorhinostomy (Endo DCR). A total of 298 patients diagnosed with unilateral primary acquired nasolacrimal duct obstruction from May 2017 to June 2021 who underwent Endo DCR were enrolled. The patients were divided into the Regenwel group (152 patients) and the Control group (146 patients) that did not use Regenwel during surgery, and the medical records were compared and analyzed retrospectively. Read More

Ear Nose Throat J 2022 Jun 14:1455613221108366. Epub 2022 Jun 14.

Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University.

Objective: To investigate the clinical effect of dexmedetomidine combined with dezocine in local anesthesia for endoscopic dacryocystorhinostomy (DCR).

Methods: Ninety patients undergoing elective endoscopic DCR were randomly divided into two groups, local anesthesia group (LA group n = 45) and general anesthesia group (GA group, n = 45). These subjects were all American Society of Anesthesiologists (ASA)-Physical Status I-II patients. Read More

Orbit 2022 May 31. Epub 2022 May 31.

Department of Ophthalmology, Jozef Strus City Hospital, Poznan, Poland.

Eye (Lond) 2022 May 19. Epub 2022 May 19.

Department of Ophthalmology, Guru Nanak Eye Centre (Associated with Maulana Azad Medical College), New Delhi, India.

Objective: To study the outcomes of transcanalicular laser dacryocystorhinostomy (TCL-DCR) with endonasal augmentation in acute versus post-acute dacryocystitis and compare it with external DCR in post-acute settings.

Methods: A prospective, randomised study was conducted in 90 adult cases of Acute dacryocystitis. All the patients were started on systemic antibiotics and a 4 mm × 4 mm osteotomy was created using TCL-DCR. Read More

Comb Chem High Throughput Screen 2022 May 9. Epub 2022 May 9.

Faculty of Medicine, Cairo University.

Introduction TLRs are fundamental elements in the orchestration of innate immune system. These receptors seem to be responsible for the inflammation and fibrosis in chronic dacryocystitis. The aim of the present study was to investigate the role of toll-Like receptors (TLR2 and TLR4) signaling pathway and its downstream effector chemokine genes in the pathogenesis of chronic dacryocystitis. Read More

Rom J Ophthalmol 2022 Jan-Mar;66(1):41-48

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

To study the long-term outcomes of lacrimal canalicular trephination (LCT) with viscoelastic-assisted monocanalicular stenting (VAMS) for the treatment of epiphora secondary to lacrimal canalicular obstructions (LCO). Our study was a retrospective interventional work. All patients diagnosed with LCO, having morbid epiphora (Munk's scale ≥ 2), were included. Read More

Orbit 2022 Apr 30:1-5. Epub 2022 Apr 30.

Department of Anesthesiology, Albany Medical College, Albany, New York, USA.

Purpose: An emerging body of evidence indicates that intravenous ketorolac (IVK) reduces pain scores and the requirement for opioid analgesics in a variety of oculofacial procedures. This study was performed to assess the impact of timing of IVK administration on these benefits after external dacryocystorhinostomy (DCR).

Methods: Patients were randomized to receive IVK before (n = 50), during (n = 50), or after DCR (n = 50). Read More

Vestn Oftalmol 2022 ;138(2):100-107

Research Institute of Eye Diseases, Moscow, Russia.

This article reviews etiological factors in the development of lacrimal punctal stenosis, modern diagnostic techniques, as well as both conservative and surgical treatment methods. The presented analysis is based on data from 67 literary sources, which provide information on conventional and high-tech examination and treatment methods of patients with lacrimal punctal stenosis. Particular attention is paid to various aspects of punctoplasty - the most common surgical intervention used to treat this pathology. Read More

Ophthalmic Plast Reconstr Surg 2022 Apr 25. Epub 2022 Apr 25.

Govindram Seksaria Institute of Dacryology, LV Prasad Eye Institute, Hyderabad, India.

Purpose: To study the metagenome of the microbes present on the extubated lacrimal stents following a dacryocystorhinostomy.

Methods: A prospective study was performed on 10 consecutive extubated lacrimal stents obtained for the metagenomic analysis from the patients following an endoscopic dacryocystorhinostomy. The stents were extubated at 4 weeks postoperatively under endoscopic guidance and immediately transported on ice to the laboratory. Read More

Diagnostics (Basel) 2022 Apr 8;12(4). Epub 2022 Apr 8.

Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.

Background: Removal of the surrounding bone during dacryocystorhinostomy may present a higher risk of skull base injury in patients with frontal sinus aplasia. We used sinus plain films to predict cases with a greater risk of a reduced skull base distance in dacryocystorhinostomy.

Methods: Sinus plain films and computed tomography data from patients were retrospectively evaluated. Read More

Ocul Immunol Inflamm 2022 Apr 20:1-3. Epub 2022 Apr 20.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, India.

Purpose: To report an unusual case of an ectopic lacrimal fistula in a setting of a naso-orbito-ethmoid fracture.

Case Report: The present case demonstrates a right-sided ectopic lacrimal fistula just below the glabella on the contralateral side on the outer edge of the midline. CT-Dacryocystography demonstrated a large dilated right lacrimal sac with a partly sequestered fundus traversing through the frontal process of the maxilla and frontal bone, close to the skull base and communicating with the fistula. Read More

Acta Otolaryngol 2022 Mar-Apr;142(3-4):316-322. Epub 2022 Apr 5.

Department of Ophthalmology, University of Toyama, Toyama, Japan.

Background: In the external dacryocystorhinostomy (DCR), a sutured anastomosis technique performed between the nasal mucosal and lacrimal sac flaps reported by Dupuy-Dutemps and Bourguet was the gold standard and was believed to lead to the success of the surgery. However, because of the small working space, a flap suturing technique has not been completely established in endonasal DCR (END-DCR).

Objectives: The effect of the modified flap suture anastomosis technique using a Sonopet ultrasonic bone aspirator was retrospectively compared to that using a diamond burr in patients with nasolacrimal duct obstruction. Read More

Eye (Lond) 2022 Apr 4. Epub 2022 Apr 4.

Division of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA and the Edwin and Fannie Gray Hall Center for Human Appearance, The University of Pennsylvania, Perelman School of Medicine, Pennsylvania, USA.

Background: Congenital nasolacrimal duct obstruction (CNLDO) is common in Down Syndrome (DS), and more difficult to treat. Our purpose was to describe the management of CNLDO in paediatric patients with DS.

Methods: Retrospective cohort study. Read More

Cureus 2022 Feb 21;14(2):e22442. Epub 2022 Feb 21.

Otolaryngology - Head and Neck Surgery, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, MAR.

Sinonasal malignant melanoma is a rare but aggressive tumor of the head and neck area. It has a poor prognosis. Common symptoms are nasal obstruction, epistaxis, or purulent rhinorrhea. Read More

J Ophthalmol 2022 23;2022:3996854. Epub 2022 Mar 23.

Department of Ophthalmic Plastic and Reconstructive Surgery, Istanbul Beyoglu Eye Research and Training Hospital, Bereketzade Cami Sk. No. 2, Beyoglu, Istanbul 34421, Turkey.

Purpose: To compare the outcomes of transcanalicular diode laser-assisted dacryocystorhinostomy (TCL-DCR), nonendoscopic endonasal dacryocystorhinostomy (NEN-DCR), and external dacryocystorhinostomy (EXT-DCR) as first-line treatments for functional epiphora.

Methods: This multicenter, retrospective, case-control study included 135 eyes of 135 patients with functional epiphora (86 females and 49 males). Functional epiphora was diagnosed based on a patent lacrimal system with a delay in the fluorescein dye disappearance test (FDDT) or dacryoscintigraphy (DSG) and no ocular surface or eyelid abnormalities. Read More

Int Ophthalmol 2022 Mar 31. Epub 2022 Mar 31.

Department of Otorhinolaryngology, Faculty of Medicine, Ordu University, 52200, Ordu, Turkey.

Purpose: To evaluate the effect of postoperative nasal triamcinolone spray use in primary endoscopic dacryocystorhinostomy using The Lacrimal Symptom Questionnaire.

Methods: This study included a series of 50 consecutive retrospective cases with primary endoscopic dacryocystorhinostomy and with silicone stent implantation who were followed up for 6 months postoperatively. Patients using nasal triamcinolone spray for 3 months postoperatively were included in the triamcinolone group. Read More

PLoS One 2022 28;17(3):e0266040. Epub 2022 Mar 28.

Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Purpose: To investigate the association between the bony nasolacrimal duct (NLD) size and outcomes of nasolacrimal silicone intubation for incomplete primary acquired nasolacrimal duct obstruction (PANDO).

Methods: Patients who underwent silicone intubation for incomplete PANDO and had undergone facial computed tomography (CT) were included. Surgical success was judged by both epiphora improvement and normalized tear meniscus height (TMH; < 300 μm) on anterior segment optical coherence tomography at 3 months after tube removal. Read More

Braz J Otorhinolaryngol 2022 Feb 28. Epub 2022 Feb 28.

Hospital Edmundo Vasconcelos, Centro de Otorrinolaringologia e Fonoaudiologia, São Paulo, SP, Brazil.

Objective: To analyze the anatomical relationship between the lacrimal sac and the agger nasi cell on Computed Tomography (CT); to correlate the right and left sides on each scan.

Methods: CT scans of adult patients were reviewed for pneumatization of the agger nasi and its relationship to the lacrimal sac. The degree of agreement between the right and left sides was also evaluated. Read More

Ophthalmic Plast Reconstr Surg 2022 Mar 23. Epub 2022 Mar 23.

Department of Otolaryngology, Head and Neck Surgery, Shaare Zedek Medical Center, The Hebrew University, Jerusalem, Israel Department of Ophthalmology, Shaare Zedek Medical Center, The Hebrew University, Jerusalem, Israel.

Background: Endoscopic Dacryocystorhinostomy (DCR) has become an acceptable alternative to the open approach, with considerable data demonstrating comparable success rates and advantages such as avoiding skin incisions. Drug-eluting bio-absorbable materials are relatively new innovation in sinus surgery, the usefulness of such materials in Endoscopic DCR is yet to be described.

Methods: A retrospective analysis of 253 endoscopic DCR procedures performed by a single surgical team from September 2011 to June 2020 was performed. Read More

Eur Arch Otorhinolaryngol 2022 Mar 23. Epub 2022 Mar 23.

Department of Otorhinolaryngology, Head and Neck Surgery, Peking University People's Hospital, Beijing, 100044, China.

Background: Although endoscopic dacryocystorhinostomy (DCR) is a standard procedure for nasolacrimal duct obstruction (NLDO), the failure rate remains approximately 10%. A small lacrimal sac is considered the main reason for surgical failure. We explored the efficacy of endoscopic DCR for the treatment of NLDO with a small lacrimal sac. Read More

Int J Ophthalmol 2022 18;15(3):413-419. Epub 2022 Mar 18.

Department of Orbital and Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.

Aim: To demonstrate the outcomes of endoscopic endonasal dacryocystorhinostomy (En-DCR) with an novel lacrimal ostium stent (LOS) which was performed in patients with recurrent epiphora after failed external dacryocystorhinostomy (Ex-DCR) and analyze the causes of failed Ex-DCR.

Methods: From September 2015 and December 2017, the clinic data of 29 cases suffered from recurrent epiphora after failed Ex-DCR was reviewed. The LOS were implanted into the ostium at the end of the revisional surgery. Read More

J Fr Ophtalmol 2022 06 8;45(6):e249-e251. Epub 2022 Mar 8.

Service d'oto-rhino-laryngologie, centre hospitalier Poissy Saint-Germain-en-Laye, 10, rue du Champ-Gaillard, 78303 Poissy, France.

Vestn Otorinolaringol 2022 ;87(1):75-80

Research Institute of Eye Diseases, Moscow, Russia.

In connection with the pandemic of coronavirus infection, it is urgent to develop measures to prevent the intraoperative spread of coronavirus particles and infection of the operating room staff.

Objective: Generalization and analysis of available data concerning local antiseptic therapy for the prevention of coronavirus infection during endonasal interventions on the lacrimal tract.

Material And Methods: The search for literature sources was carried out using MEDLINE search engines and the Russian Science Citation Index for queries with the keywords "COVID-19", "coronavirus infection", "antiseptics", "protocol for otorhinolaryngological operations", "dacryosurgical operations" and similar in various combinations. Read More

Beyoglu Eye J 2022 18;7(1):25-29. Epub 2022 Feb 18.

Department of Ophthalmology, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.

Objectives: In our clinic, although we prefer to perform dacryocystorhinostomy (DCR) under general anesthetics, we also perform it under local anesthetics for patients with a high risk of general anesthesia. Herein this study, we aimed to present our experiences in external DCR under both general and local anesthetics in a tertiary clinic.

Methods: Medical records of the patients who had epiphora, were followed up in the oculoplastic section between January 2014 and December 2020 were collected. Read More

Am J Ophthalmol Case Rep 2022 Mar 3;25:101344. Epub 2022 Feb 3.

Department of Ophthalmology, Clinical Hospital, School of Medicine, University of São Paulo (Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo - HCFMUSP), Av. Dr. Arnaldo, 455, São Paulo, Brazil.

Purpose: Radioiodine therapy, a standard treatment for differentiated thyroid carcinomas, is associated with several adverse events including lacrimal drainage system obstruction. Herein, we describe the first case of duct lumen recanalization using dacryoendoscopy for lacrimal passage obstruction and stenosis after radioiodine therapy.

Observations: A 48-year-old female treated with radioiodine therapy for differentiated thyroid carcinoma 5 years prior presented with epiphora in both eyes. Read More

Indian J Ophthalmol 2022 Mar;70(3):962-964

Institute of Ophthalmology, Jawaharlal Nehru Medical, College, AMU, Aligarh, UP; Orbit Oculoplasty, Reconstructive and Aesthetic Service, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.

Purpose: Fibrin glue was used for anastomosis of lacrimal sac and nasal mucosal flaps and was compared with the conventional suture technique in external dacryocystorhinostomy.

Methods: A prospective interventional randomized control study in which 50 consecutive patients of primary acquired nasolacrimal duct obstruction (PANDO) were equally allocated into two groups. The case group underwent glued technique of external dacryocystorhinostomy (Ext DCR) in which fibrin glue was used for the apposition of the anterior lacrimal sac and nasal mucosal flaps. Read More

Indian J Ophthalmol 2022 Mar;70(3):717-718

Department of Ophthalmology, Sakra World Hospital, Bangalore, Karnataka, India.

Acta Otorrinolaringol Esp (Engl Ed) 2022 Jan-Feb;73(1):11-18

Servicio de Otorrinolaringología, Hospital General de Requena, Valencia, Spain.

Introduction: Chronic dacryocystitis is the condition secondary to permanent lacrimonasal duct stenosis (LNDS) that generates epiphora and recurrent conjunctivitis. Endoscopic dacryocystorhinostomy (EDCR) is a more natural route than the external route and offers higher success rates than the laser technique. We value this centre's experience in this procedure. Read More

Klin Monbl Augenheilkd 2022 Feb 18. Epub 2022 Feb 18.

Otorhinolaryngology, Medova Hospital, Konya, Turkey.

Background: In the present study, we aimed to evaluate the surgical outcomes of the fusiform anastomosis technique in external dacryocystorhinostomy (ex-DCR) that we designed in the form of a physiological tube, which sufficiently covered the bone ostium with the mucosa.

Material And Methods: This was a retrospective observational study that included 145 eyes of 131 patients who underwent ex-DCR due to nasolacrimal duct obstruction. The patients were divided into two groups. Read More

Klin Monbl Augenheilkd 2022 Jun 18;239(6):799-803. Epub 2022 Feb 18.

Department of Ophthalmology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.

Purpose: This study aimed to compare anatomical and functional outcomes of external dacryocystorhinostomy (EX-DCR) and transcanalicular multidiode laser dacryocystorhinostomy (TDL-DCR) in patients with primary acquired nasolacrimal duct obstruction (PANDO).

Methods: This study was conducted on 60 eyes of 60 patients with PANDO. The study subjects were randomly divided into two groups. Read More