2,587 results match your criteria Dacryoadenitis


Lacrimal Duct Obstruction and Infection Associated with Non-Traumatic Corneal Perforation: A Case Series.

Int Med Case Rep J 2022 23;15:313-322. Epub 2022 Jun 23.

Department of Ophthalmology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.

Purpose: To report a case series of lacrimal duct obstruction and infection associated with non-traumatic corneal perforation.

Case Series: This study included 6 eyes in 6 patients with non-traumatic corneal perforation treated between April 2019 and March 2021. All 6 cases were associated with lacrimal duct obstruction and infection. Read More

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Dacryoadenitis in giant cell arteritis.

J Fr Ophtalmol 2022 Jun 24. Epub 2022 Jun 24.

CHU du Kremlin-Bicêtre, 78, avenue du Général Leclerc, 94270 Le Kremlin-Bicêtre, France.

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Bilateral Dacryocystitis Resulting from Granulomatosis with Polyangiitis.

Am J Ophthalmol 2022 Jun 22. Epub 2022 Jun 22.

Vanderbilt Eye Institute, Nashville, TN.

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A novel case of - associated acute dacryocystitis.

Orbit 2022 Jun 22:1-3. Epub 2022 Jun 22.

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

This study aims to report an acute dacryocystitis associated with infection. The patient's medical records and laboratory were thoroughly assessed. A thorough literature search was performed in PubMed database. Read More

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Early Dry Eye Disease Onset in a NOD.H-2h4 Mouse Model of Sjögren's Syndrome.

Invest Ophthalmol Vis Sci 2022 Jun;63(6):18

Department of Ophthalmology, University of Missouri, Columbia, Missouri, United States.

Purpose: To develop a mouse model of human dry eye disease (DED) for investigation of sex differences in autoimmune-associated dry eye pathology.

Methods: Ocular surface disease was assessed by quantifying corneal epithelial damage with lissamine green stain in the NOD.H-2h4,IFNγ-/-,CD28-/- (NOD. Read More

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PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome-Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice.

Invest Ophthalmol Vis Sci 2022 Jun;63(6):12

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

Purpose: To investigate the effects and mechanisms of fenofibrate, a synthetic ligand of peroxisome proliferator-activated receptor α (PPAR-α), on autoimmune dacryoadenitis in a mouse model of Sjögren syndrome (SS) dry eye.

Methods: Male nonobese diabetic (NOD) mice were fed chow with or without 0.03% fenofibrate for 8 weeks, and clinical scores were determined by assessing tear secretion, fluorescein, and hematoxylin and eosin staining. Read More

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Detection & analysis of inflammatory cytokines in tears of patients with lacrimal duct obstruction.

Indian J Med Res 2021 06;154(6):888-894

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, P.R. China.

Background & Objectives: Tear proteomic changes can be a candidate etiopathogenesis of lacrimal duct obstruction diseases (LDODs). Studies on proteomics have focused primarily on nasolacrimal duct obstruction, and some specific inflammatory cytokines such as interferon (IFN)-α2a, interleukin (IL)-8 and IL-10, have not been investigated. In addition, differences in inflammatory cytokines in tears according to the LDOD subtype have not been reported. Read More

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Acute suppurative bacterial dacryoadenitis with abscess formation in a child.

Can J Ophthalmol 2022 May 24. Epub 2022 May 24.

Royal Victoria Hospital, Belfast, United Kingdom.

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The association of cosmetic-related lacrimal sac black deposits with primary-acquired nasolacrimal duct obstruction and dry eye disease.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):220-224. Epub 2022 Apr 18.

Division of Oculoplastic and Orbit, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To determine the incidence of cosmetic-related lacrimal sac black deposits (LSBDs) in primary-acquired nasolacrimal duct obstruction (PANDO) biopsies and the role of LSBD in the pathogenesis of PANDO, in addition to their association with dry eye disease (DED).

Methods: A clinicopathological study included all patients who underwent surgical management of PANDO. We excluded patients in whom lacrimal sac biopsy was not taken during the surgery. Read More

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Orbital involvement in lacrimal drainage disorders.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):204-208. Epub 2021 Nov 17.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, Telangana, India.

Lacrimal sac is situated anterior to the orbital septum, which acts as a barrier, thus limiting the posterior migration of the pathologies affecting the lacrimal drainage system. Certain pathologies can breach this barrier and secondarily involve the orbit causing significant clinical manifestations. This posterior migration of pathology also has a significant influence on the management and outcomes. Read More

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November 2021

Presumed acute suppurative bacterial dacryoadenitis with concurrent severe acute respiratory syndrome coronavirus-2 infection.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):266-268. Epub 2022 Apr 18.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Acute suppurative bacterial dacryoadenitis (ASBD) was not reported to occur following severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We are presenting a unique case of concurrent presumed ASBD with SARS-CoV-2 infection. A 23-year-old previously healthy male presented with right upper eyelid swelling and pain over the lacrimal gland area for 3 days. Read More

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Clinical Characteristics of Idiopathic Orbital Inflammation Syndrome in Relation to Intraocular Pressure.

Clin Ophthalmol 2022 11;16:1467-1473. Epub 2022 May 11.

Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.

Purpose: To investigate the clinical characteristics of idiopathic orbital inflammation and changes in intraocular pressure (IOP) before and after its treatment.

Patients And Methods: We retrospectively studied 20 eyes from the medical records of 19 patients who were diagnosed with idiopathic orbital inflammation between April 1, 2004, and April 30, 2019, at Toyama University Hospital. The inflammation site (type of disease), treatment provided, IOP before and after treatment, and the symptoms (proptosis, decreased ocular movements or diplopia, periorbital edema, and ocular pain) were analyzed. Read More

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Outcome of transcanalicular laser dacryocystorhinostomy with endonasal augmentation in acute versus post-acute dacryocystitis.

Eye (Lond) 2022 May 19. Epub 2022 May 19.

Department of Ophthalmology, Guru Nanak Eye Centre (Associated with Maulana Azad Medical College), New Delhi, India.

Objective: To study the outcomes of transcanalicular laser dacryocystorhinostomy (TCL-DCR) with endonasal augmentation in acute versus post-acute dacryocystitis and compare it with external DCR in post-acute settings.

Methods: A prospective, randomised study was conducted in 90 adult cases of Acute dacryocystitis. All the patients were started on systemic antibiotics and a 4 mm × 4 mm osteotomy was created using TCL-DCR. Read More

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Solitary fibrous tumour of lacrimal sac masquerading as lacrimal sac mucocele: a diagnostic and surgical dilemma.

BMJ Case Rep 2022 May 17;15(5). Epub 2022 May 17.

Department of Pathology, Prolife Diagnostics, Bhubaneswar, Odisha, India.

Swellings in medial canthal area in eye most often involve the lacrimal sac, the commonest aetiology being chronic dacryocystitis. Very rarely, there is a deviation in the routine diagnosis when the pathology comes out to be a lacrimal sac tumour. We report the case of a young man who presented with a medial canthal mass not extending above the medial canthal ligament. Read More

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Toll-Like Receptor signaling in the pathogenesis of chronic dacryocystitis: Implication of c-FOS transcription factor and its downstream effector chemokine genes CCL2, CCL4, CXCL3, CXCR4 with shift of the M1/M2 macrophage phenotype.

Comb Chem High Throughput Screen 2022 May 9. Epub 2022 May 9.

Faculty of Medicine, Cairo University.

Introduction TLRs are fundamental elements in the orchestration of innate immune system. These receptors seem to be responsible for the inflammation and fibrosis in chronic dacryocystitis. The aim of the present study was to investigate the role of toll-Like receptors (TLR2 and TLR4) signaling pathway and its downstream effector chemokine genes in the pathogenesis of chronic dacryocystitis. Read More

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Epstein-Barr Virus Dacryoadenitis in a Young Woman.

Intern Med 2022 15;61(10):1629. Epub 2022 May 15.

Division of General Medicine, Department of Comprehensive Medicine 1, Saitama Medical Center, Jichi Medical University, Japan.

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The importance of considering the possibility of ocular sporotrichosis in areas with high incidence rates of sporotrichosis.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Ophthalmology Service, Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, Brazil.

Ocular sporotrichosis involving adnexa can present in 4 types: granulomatous conjunctivitis, dacryocystitis, Parinaud oculoglandular syndrome, and bulbar conjunctivitis. The incidence of ocular sporotrichosis has increased in regions with high incidence rates of sporotrichosis. We present a series of three cases of ocular involvement by the fungus Sporothrix species, including its manifestations, approaches, and relevance in areas where sporotrichosis has considerable incidence rates. Read More

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Misdiagnosis of fungal infections of the orbit.

Can J Ophthalmol 2022 May 4. Epub 2022 May 4.

From the Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address:

Objective: To evaluate the accuracy of the initial diagnosis in the case of fungal infections of the orbit and identify factors that may influence patient outcomes.

Methods: An institutional review board-approved retrospective chart review was conducted across 2 large academic centres to identify cases of fungal infections involving the orbit from January 1, 1998, to November 15, 2019. Data collected included patient demographics, past medical history, examination findings, diagnosis, treatment, imaging, and outcomes. Read More

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Primary Monocanalicular Stent Intubation for Children With Congenital Nasolacrimal Duct Obstruction: Surgical Outcome and Risk Factors.

Ophthalmic Plast Reconstr Surg 2022 May 3. Epub 2022 May 3.

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

Purpose: To determine the risk factors impacting the surgical success of primary monocanalicular stent intubation for congenital nasolacrimal duct obstruction (CNLDO).

Methods: This is a retrospective interventional case series of patients 18 years and younger treated more than a 12-year period with monocanalicular stent intubation with inferior turbinate fracture for CNLDO by a single surgeon. Patients with dacryocystoceles, dacryocystitis, Down syndrome and previous tear duct surgery were excluded. Read More

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Emerging antimicrobial resistance and need for antimicrobial stewardship for ocular infections in India: A narrative review.

Indian J Ophthalmol 2022 05;70(5):1513-1521

Department of Medical Affairs, Novartis Healthcare Private Limited, Mumbai, Maharashtra, India.

Patients with ocular infections are at increased risk of vision impairment and may require immediate medical care to preserve their vision. Management of ocular bacterial infections has evolved in recent years and includes a pragmatic selection of broad-spectrum antibiotics based on the causative bacteria. Nevertheless, the treatment of bacterial ocular infections is increasingly becoming a challenge, as the causative bacterium acquires resistance to antibiotics through intrinsic and acquired methods. Read More

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Erdheim-Chester disease: look it in the eye. An orbital MRI study.

Haematologica 2022 04 28. Epub 2022 Apr 28.

Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Service de Neuroradiologie, Paris, France; Service de neuroimagerie, C.H.N.O. des Quinze-Vingts, Paris.

Erdheim-Chester disease (ECD) is a rare L-group histiocytosis. Orbital involvement is found in a third of cases, but few data are available concerning the radiological features of ECD-related orbital disease (ECD-ROD). Our aim was to characterize the initial radiological phenotype and outcome of patients with ECD-ROD. Read More

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Improvement in Dacryoendoscopic Visibility after Image Processing Using Comb-Removal and Image-Sharpening Algorithms.

J Clin Med 2022 Apr 7;11(8). Epub 2022 Apr 7.

Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba 305-8575, Japan.

Recently, a minimally invasive treatment for lacrimal passage diseases was developed using dacryoendoscopy. Good visibility of the lacrimal passage is important for examination and treatment. This study aimed to investigate whether image processing can improve the dacryoendoscopic visibility using comb-removal and image-sharpening algorithms. Read More

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Ocular adnexal marginal zone lymphoma arising in a patient with immunoglobulin-G4-related ophthalmic disease: A 4-year delay in diagnosis.

Saudi J Ophthalmol 2021 Apr-Jun;35(2):164-166. Epub 2022 Feb 18.

Department of Ophthalmology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.

Ocular adnexal marginal zone B cell lymphomas (MZBLs) make up the majority of lymphomas arising from the ocular adnexa. Immunoglobulin-G4 (IgG4)-related disease is a recently proposed entity with several unique clinicopathological features, such as enlargement of affected organs, elevated serum IgG4 level, and infiltration with IgG4-positive plasma cells. Ocular adnexal MZBLs are reported to arise in IgG4-related sclerosing dacryoadenitis, indicating a possible link between the two conditions. Read More

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February 2022

Orbital Inflammation Caused by Aminobisphosphonates.

J Ophthalmic Vis Res 2022 Jan-Mar;17(1):118-122. Epub 2022 Jan 21.

Division of Orbital and Ophthalmic Plastic Surgery, Hospital Italiano de Buenos Aires, Argentina.

The aim of this review was to describe orbital inflammation secondary to aminobisphosphonates by analyzing demographic data, clinical presentation, and treatment of the disease. This is a narrative literature review. The search was performed using databases such as Ovid/MEDLINE and COCHRANE. Read More

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January 2022

Lacrimal Sac Tumors: A Case Series.

Ocul Oncol Pathol 2022 Feb 18;8(1):42-51. Epub 2021 Oct 18.

Medical Education, Bangladesh Eye Hospital and Institute, Dhaka, Bangladesh.

Objective: The aim of the study was to describe the clinical presentation, management strategies, and outcomes in a case series of primary lacrimal sac tumors.

Methods: This retrospective study was conducted in Sheikh Fajilatunnessa Mujib Eye Hospital and Training Institute, Bangladesh, from July 1 to December 31, 2020, and included all patients who were evaluated, treated, and followed up for at least 6 months from January 2013 to October 2020. One patient developed a recurrence of the adenocarcinoma of the lacrimal sac after 1 year of primary treatment. Read More

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February 2022

Acute Dacryoadenitis due to Primary Epstein-Barr Virus Infection.

Open Forum Infect Dis 2022 Apr 22;9(4):ofac086. Epub 2022 Feb 22.

Department of Internal Medicine, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.

We herein present the case of a 28-year-old male patient who presented with fever and bilateral upper eyelid edema without other upper airway symptoms and was diagnosed with acute dacryoadenitis due to Epstein-Barr virus (EBV) infection. The patient's medical history was unremarkable. Laboratory tests revealed lymphocytosis with atypical lymphocytes and abnormal liver function tests. Read More

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Endoscopic dacryocystorhinostomy for refractory nasolacrimal duct obstruction with a small lacrimal sac (≤ 5 mm in diameter).

Eur Arch Otorhinolaryngol 2022 Mar 23. Epub 2022 Mar 23.

Department of Otorhinolaryngology, Head and Neck Surgery, Peking University People's Hospital, Beijing, 100044, China.

Background: Although endoscopic dacryocystorhinostomy (DCR) is a standard procedure for nasolacrimal duct obstruction (NLDO), the failure rate remains approximately 10%. A small lacrimal sac is considered the main reason for surgical failure. We explored the efficacy of endoscopic DCR for the treatment of NLDO with a small lacrimal sac. Read More

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Management of chronic dacryocystitis cases after failed external dacryocystorhinostomy using endoscopic technique with a novel lacrimal ostium stent.

Int J Ophthalmol 2022 18;15(3):413-419. Epub 2022 Mar 18.

Department of Orbital and Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.

Aim: To demonstrate the outcomes of endoscopic endonasal dacryocystorhinostomy (En-DCR) with an novel lacrimal ostium stent (LOS) which was performed in patients with recurrent epiphora after failed external dacryocystorhinostomy (Ex-DCR) and analyze the causes of failed Ex-DCR.

Methods: From September 2015 and December 2017, the clinic data of 29 cases suffered from recurrent epiphora after failed Ex-DCR was reviewed. The LOS were implanted into the ostium at the end of the revisional surgery. Read More

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Tear miRNAs Identified in a Murine Model of Sjögren's Syndrome as Potential Diagnostic Biomarkers and Indicators of Disease Mechanism.

Front Immunol 2022 4;13:833254. Epub 2022 Mar 4.

Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, United States.

Objective: The tear miRNAome of the male NOD mouse, a model of ocular symptoms of Sjögren's syndrome (SS), was analyzed to identify unique miRNAs.

Methods: Male NOD mice, aged 12-14 weeks, were used to identify tear miRNAs associated with development of autoimmune dacryoadenitis. Age- and sex-matched male BALB/c mice served as healthy controls while age-matched female NOD mice that do not develop the autoimmune dacryoadenitis characteristic of SS were used as additional controls. Read More

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