2,384 results match your criteria Dacryoadenitis


Nasolacrimal Obstruction Following the Placement of Maxillofacial Hardware.

Craniomaxillofac Trauma Reconstr 2020 Mar 20;13(1):32-37. Epub 2020 Feb 20.

Department of Ophthalmology, University of California, San Francisco, CA, USA.

Purpose: This article reviews cases of nasolacrimal obstruction (NLO) secondary to maxillofacial hardware placement.

Methods: A retrospective review was performed at a single institution from 2012 to 2017 of patients with NLO following maxillofacial reconstruction. The study was approved by the Institutional Review Board of the University of California, San Francisco, adhered to the tenets of the Declaration of Helsinki, and was Health Insurance Portability and Accountability Act compliant. Read More

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http://dx.doi.org/10.1177/1943387520906004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311843PMC

Lithuanian version of nasolacrimal duct obstruction symptom scoring questionnaire. Cross-cultural adaptation and validation. Short and long term results.

Clin Otolaryngol 2020 Jul 7. Epub 2020 Jul 7.

Department of Otorhinolaryngology, Hospital of Lithuanian University of Health Science Kauno Klinikos, Kaunas, Lithuania.

Background: The most common cause for epiphora is nasolacrimal duct obstruction (NLDO). Epiphora may decrease the quality of life due to recurrent lacrimal sac infections, worsening vision and distress in public environments. Patency of nasolacrimal duct can be verified by various clinical tests. Read More

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http://dx.doi.org/10.1111/coa.13606DOI Listing

Ultrasonographic features of lacrimal sac in normal, PANDO and acute dacryocystitis.

Orbit 2020 Jul 7:1-2. Epub 2020 Jul 7.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute , Hyderabad, India.

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http://dx.doi.org/10.1080/01676830.2020.1789181DOI Listing

Inflammatory choroidal neovascularization associated with immunoglobulin G4-related disease: a case report.

J Med Case Rep 2020 Jul 5;14(1):89. Epub 2020 Jul 5.

Transitional Year Residency Program, The University of Texas at Austin Dell Medical School, Austin, TX, USA.

Background: Immunoglobulin G4-related disease is a recently recognized condition with pathologic features that are consistent across a wide range of organ systems. Orbital manifestations of this disease entity typically involve the lacrimal gland and lacrimal duct, extraocular muscles, orbital soft tissue, and sclera. Here, the authors report the first known case of inflammatory choroidal neovascular membrane associated with immunoglobulin G4-related disease and offer suggestions for clinical management of this enigmatic condition. Read More

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http://dx.doi.org/10.1186/s13256-020-02431-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335434PMC

Congenital lacrimal sac diverticulum.

J AAPOS 2020 Jul 1. Epub 2020 Jul 1.

Ophthalmology Department, Ramon y Cajal University Hospital.

We report the case of a 6-month-old boy with recurrent episodes of acute dacryocystitis from age 3 months to 1 year of age. The cause was determined to be congenital nasolacrimal sac diverticulum, a rare and commonly asymptomatic entity. An isolated diverticulectomy without dacryocystorhinostomy was performed because of lacrimal drainage system patency. Read More

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http://dx.doi.org/10.1016/j.jaapos.2020.03.009DOI Listing

[Clinical and laboratory characteristics of IgG4-realated disease and its diagnostic algorithm].

Ter Arkh 2019 May 15;91(5):40-48. Epub 2019 May 15.

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University).

Aim: to propose diagnostic algorithm of IgG4-related disease (IgG4-RD).

Materials And Methods: One center retrospective research. 52 pts with IgG4-RD were included. Read More

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http://dx.doi.org/10.26442/00403660.2019.05.000236DOI Listing

Diagnosis of lacrimal punctum lesions using optical coherence tomography: a preliminary study.

Int J Ophthalmol 2020 18;13(6):902-906. Epub 2020 Jun 18.

Lacrimal Center of Ophthalmology, the Third Medical Center, Chinese PLA General Hospital, Beijing 100039, China.

Aim: To study the imaging characteristics of lacrimal punctum lesion with optical coherence tomography (OCT), and provide imaging basis for the diagnosis and treatment of lacrimal punctum diseases.

Methods: A total of 25 patients (28 eyes) with epiphora and lacrimal puncta lesions were enrolled. Lacrimal puncta lesions included: punctum membrane obstruction in 7 cases (9 eyes), punctum agenesis in 1 case (1 eye), a mass protruded from the punctum in 1 case (1 eye), slit puncta in 1 case (1 eye), peri-puncta mass in 2 cases (2 eyes), chronic dacryocystitis in 4 cases (4 eyes), and primary puncta stenosis in 9 cases (10 eyes; 3 eyes mild, 4 eyes moderate and 3 eyes severe). Read More

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http://dx.doi.org/10.18240/ijo.2020.06.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270249PMC

Transcanalicular diode laser assisted dacryocystorhinostomy: A breakthrough in the treatment of acquired nasolacrimal duct obstruction.

Pak J Med Sci 2020 May-Jun;36(4):804-807

Dr. Muhammad Shahid. FCPS (Ophth), Armed Forces Institute of Ophthalmology (AFIO) Rawalpindi, Pakistan.

Objective: To evaluate the success rate of Transcanalicular Diode laser assisted Dacryocystorhinostomy (TC-DCR) in cases of acquired nasolacrimal duct obstruction (NLDO).

Methods: This Quasi-Experimental study was conducted in Armed Forces Institute of Ophthalmology (AFIO) Rawalpindi, from July 2018 to April 2019. In this study, 73 patients of chronic dacryocystitis secondary to acquired NLDO were treated by TC-DCR under general anaesthesia. Read More

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http://dx.doi.org/10.12669/pjms.36.4.1906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260931PMC

Perineuritis or infiltration of optic nerve sheath? A presentation of diffuse large B cell Gastric lymphoma.

Indian J Ophthalmol 2020 Jun;68(6):1212-1214

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, India.

Optic perineuritis is an inflammatory disorder involving the optic nerve sheath. It is currently considered as a part of idiopathic orbital inflammatory disease which also includes dacryoadenitis, orbital myositis, superior orbital fissure, and cavernous sinus syndrome (Tolosa hunt syndrome). As it is idiopathic, it is considered a diagnosis of exclusion. Read More

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http://dx.doi.org/10.4103/ijo.IJO_711_19DOI Listing
June 2020
0.927 Impact Factor

Behavior and outcomes of 70 adult lacrimal sac mucoceles.

Orbit 2020 May 21:1-5. Epub 2020 May 21.

Department of Ophthalmic Plastic and Reconstructive Surgery Service, L. V. Prasad Eye Institute , Bhubaneswar, India.

Purpose: To study the clinical profile and outcomes in adults with lacrimal sac mucoceles.

Methods: A retrospective, interventional study on consecutive adult patients with lacrimal sac mucoceles who underwent dacryocystorhinostomy (DCR)/dacryocystectomy surgery. Primary outcome measure was subsidence of lacrimal sac swelling after intervention. Read More

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http://dx.doi.org/10.1080/01676830.2020.1767155DOI Listing

Necrotizing Granulomatous Dacryoadenitis With Non-Necrotizing Granulomatous Scar Hypertrophy: Two Histological Variants of Sarcoidosis in the Same Patient.

Ophthalmic Plast Reconstr Surg 2020 May 19. Epub 2020 May 19.

Division of Ophthalmology, Albany Medical Center.

Orbital involvement with histologic necrosis is a rare manifestation of systemic sarcoidosis. The authors present a case of necrotizing dacryoadenitis in addition to non-necrotizing granulomas in a hypertrophic scar that is consistent with a diagnosis of sarcoidosis. A 60-year-old female presented with 2 months of painless right upper eyelid fullness and ptosis. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001720DOI Listing

Orbital Microscopic Polyangiitis With Secondary Angle Closure Due to Uveal Effusion.

Ophthalmic Plast Reconstr Surg 2020 May 19. Epub 2020 May 19.

Division of Oculofacial Plastic & Orbital Surgery, Gavin Herbert Eye Institute, University of California Irvine, Irvine, California, U.S.A.

A 63 year-old man presented with 3 weeks of worsening, painless left-sided proptosis, ptosis, and diplopia. Examination of the affected eye revealed normal visual acuity, normal intraocular pressure in the presence of a shallow anterior chamber, grade 1 relative afferent pupillary defect, restricted motility in all directions of gaze, and 6 mm of proptosis. Ultrasound biomicroscopy revealed uveal effusions with anterior rotation of the ciliary body causing appositional angle closure. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001725DOI Listing

[Painful orbital swelling in a 61-year-old female patient].

Internist (Berl) 2020 Jul;61(7):741-745

Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie, HELIOS Klinikum Krefeld, Lutherplatz 40, 47805, Krefeld, Deutschland.

Adenocarcinoma of the esophagus is the oncologic entity with the most progressive incidence in western countries over the last 30 years. This is caused by, among other factors, a growing rate of obesity and the associated gastroesophageal reflux disease. Typical sites of metastasis include the liver, lymph nodes and peritoneum. Read More

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http://dx.doi.org/10.1007/s00108-020-00802-3DOI Listing

CT and MRI findings in relapsing primary malignant melanoma of the lacrimal sac: a case report and brief literature review.

BMC Ophthalmol 2020 May 14;20(1):191. Epub 2020 May 14.

Department of Radiology, the Fourth Affiliated Hospital of Kunming Medical University, 176 Qing Nian Street, Kunming, People's Republic of China.

Background: Primary lacrimal sac melanoma is an extremely rare condition with fewer than 50 cases reported so far. Clinically, its symptoms resemble those of dacryocystitis, leading to frequent misdiagnosis. During diagnosis, imaging examination is often performed to differentiate tumors from inflammation. Read More

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http://dx.doi.org/10.1186/s12886-020-01356-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222429PMC

Panophthalmitis and Visual Loss as a Complication of Acute Dacryocystitis.

Ophthalmic Plast Reconstr Surg 2020 Apr 23. Epub 2020 Apr 23.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, Telangana, India.

Acute dacryocystitis causing visual loss due to development of orbital complications like central retinal artery or ophthalmic artery occlusion, retinal vein occlusions, and optic neuritis is rare but a known entity. However, development of scleral abscess and panophthalmitis as a complication of acute dacryocystitis, leading to loss of vision, has not been described earlier. To the best of the authors' knowledge, this is the first report describing this mode of visual loss in acute dacryocystitis. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001686DOI Listing

Sarcoid-like granulomatous orbitopathy-presentation, systemic involvement and clinical outcome.

Eye (Lond) 2020 Apr 21. Epub 2020 Apr 21.

Adnexal Service, Moorfields Eye Hospital, London, EC1V 2PD, UK.

Aim: To describe patients with sarcoid-like granulomatous orbitopathy (SLGO), the rate of known and subsequent systemic sarcoidosis, and the treatment and outcome for the condition.

Patients And Methods: Retrospective review of patients with SLGO presenting between 1990 and 2018, excluding solely lid or lacrimal drainage disease.

Results: Sixty-one patients (45 female; 74%) were identified, 54 having biopsy-proven sarcoidosis (47 orbital, 24 prior extra-orbital), and half were Afro-Caribbean. Read More

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http://dx.doi.org/10.1038/s41433-020-0874-4DOI Listing

Modified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.

J Craniofac Surg 2020 Jul-Aug;31(5):1464-1466

Department of Otolaryngology Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang City, China.

Purpose: Endoscopic dacryocystorhinostomy (EDCR) is advantageous in that it avoids facial scar formation, does not damage the medial canthus ligament, and recovers quickly. The main purpose of EDCR is to establish a fistula large enough to completely expose the lacrimal sac and avoid complications. Accurate location of lacrimal sac and complete opening of lacrimal sac are the keys to successful operation. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006493DOI Listing
April 2020
0.676 Impact Factor

Endoscopic Endonasal Dacryocystorhinostomy With a Novel Lacrimal Ostium Stent in Chronic Dacryocystitis Cases With Small Lacrimal Sac.

J Craniofac Surg 2020 Jul-Aug;31(5):1348-1352

Department of Orbital & Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou.

Purpose: To investigate feasibility of endoscopic endonasal dacryocystorhinostomy (EE-DCR) with an novel lacrimal ostium stent (LOS) intubation for patients with chronic dacryocystitis with small lacrimal sac.

Methods: Patients diagnosed as chronic dacryocystitis with small lacrimal sac who preferred to surgery treatment between March 1st, 2012 and May 1st, 2015. All included subjects were randomly divided into 2 groups (Group A and Group B). Read More

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http://dx.doi.org/10.1097/SCS.0000000000006359DOI Listing

Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction.

Cochrane Database Syst Rev 2020 04 7;4:CD012309. Epub 2020 Apr 7.

University of Hong Kong, Department of Ophthalmology, Rm 301, Blk B, Cyberport 4, 100 Cyberport Road, Cyberport, Hong Kong, 00000.

Background: Nasolacrimal duct obstruction (NLDO) is a condition that results in the overflow of tears (epiphora) or infection of the nasolacrimal sac (dacryocystitis). The etiology of acquired NLDO is multifactorial and is not fully understood. Dacryocystorhinostomy (DCR) is the surgical correction of NLDO, which aims to establish a new drainage pathway between the lacrimal sac and the nose. Read More

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http://dx.doi.org/10.1002/14651858.CD012309.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138426PMC

Characterization and Management of Inflammatory Eye Disease in Patients with Hidradenitis Suppurativa.

Ocul Immunol Inflamm 2020 Apr 7:1-6. Epub 2020 Apr 7.

Department of Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

: To assess the spectrum and treatment outcomes of inflammatory eye disease (IED) in subjects with hidradenitis suppurativa (HS).: We conducted a single center retrospective chart review of 236 patients with HS seen for ophthalmic examination between 2013 and 2018.: Of 236 subjects with HS, 22 subjects (9. Read More

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http://dx.doi.org/10.1080/09273948.2020.1739718DOI Listing

Toward a chimeric vaccine against multiple isolates of Mycobacteroides - An integrative approach.

Life Sci 2020 Jun 10;250:117541. Epub 2020 Mar 10.

Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Greater Noida, India.

Aim: Nontuberculous mycobacterial (NTM) infection such as endophthalmitis, dacryocystitis, and canaliculitis are pervasive across the globe and are currently managed by antibiotics. However, the recent cases of Mycobacteroides developing drug resistance reported along with the improper practice of medicine intrigued us to explore its genomic and proteomic canvas at a global scale and develop a chimeric vaccine against Mycobacteroides.

Main Methods: We carried out a vivid genomic study on five recently sequenced strains of Mycobacteroides and explored their Pan-core genome/proteome in three different phases. Read More

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http://dx.doi.org/10.1016/j.lfs.2020.117541DOI Listing
June 2020
2.702 Impact Factor

Review of a novel disease entity, immunoglobulin G4-related disease.

J Korean Assoc Oral Maxillofac Surg 2020 Feb 26;46(1):3-11. Epub 2020 Feb 26.

Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.

Immunoglobulin G4 (IgG4)-related dacryoadenitis and sialoadenitis (IgG4-DS) are part of a multiorgan fibroinflammatory condition of unknown etiology termed IgG4-related disease (IgG4-RD), which has been recognized as a single diagnostic entity for less than 15 years. Histopathologic examination is critical for diagnosis of IgG4-RD. CD4+ T and B cells, including IgG4-expressing plasma cells, constitute the major inflammatory cell populations in IgG4-RD and are thought to cause organ damage and tissue fibrosis. Read More

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http://dx.doi.org/10.5125/jkaoms.2020.46.1.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049757PMC
February 2020

A Retrospective Study of Establishment of Association Between Deviated Nasal Septum, Sinusitis and Chronic Dacryocystitis.

Indian J Otolaryngol Head Neck Surg 2020 Mar 2;72(1):70-73. Epub 2019 Nov 2.

Department of ENT, Navodaya Medical College, Raichur, Karnataka India.

The purpose of this study was to determine whether there is any correlation between dacryocystitis with deviated nasal septum and sinusitis. A retrospective study of 50 patients who were diagnosed with dacryocystitis were included in the study. The patients included were operated between July 2018 and February 2017. Read More

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http://dx.doi.org/10.1007/s12070-019-01745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040112PMC

Bilateral interstitial keratitis, erythema nodosum and atrial fibrillation as presenting signs of polyarteritis nodosa.

Am J Ophthalmol Case Rep 2020 Jun 21;18:100619. Epub 2020 Feb 21.

Athens Vision Eye Institute, Athens, Greece.

Purpose: To report a case of Polyarteritis Nodosa (PAN) presenting as bilateral episcleritis and interstitial keratitis along with erythema nodosum and atrial fibrillation and to review the ophthalmic literature on PAN with anterior segment findings.

Observations: A 35-year old man presented with a two-month history of bilateral episcleritis, skin lesions consistent with erythema nodosum, joint effusions and episodes of prolonged diarrhea and atrial fibrillation. Ophthalmic examination was significant for bilateral diffuse episcleral injection and nummular corneal stromal infiltrates. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044707PMC

Infantile Endoscopic Dacryocystorhinostomy: Indications, Anatomical considerations, and Outcomes.

Ophthalmic Plast Reconstr Surg 2020 Feb 24. Epub 2020 Feb 24.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, India.

The purpose of this case series is to report the demographic profile, indications, anatomical considerations, and outcomes of Endonasal endoscopic DCR in the infants. Five eyes of 3 infants underwent IEnDCR with a mean age of 4.26 months (range: 23 days-8 months). Read More

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http://dx.doi.org/10.1097/IOP.0000000000001615DOI Listing
February 2020

Surgical Treatment of Dacryocystitis by Using a Venous Catheter.

J Craniofac Surg 2020 Jun;31(4):1120-1121

Department of Biomedical Sciences, Eye Clinic.

Purpose: Aim of this work is to highlight the advantages of a new surgical technique performed over 15 patients affected dacryocystitis and treated by using a venous catheter.The arrangement of a 30 mm venous catheter used at the end of a dacryocystectomy (DCT) was performed in 15 patients with dacryocystitis. The venous catheter was removed at 30 days after the surgery. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006237DOI Listing

Orbital Sarcoidosis in a High TB Endemic Country - A Case Series from South India.

Ocul Immunol Inflamm 2020 Feb 19:1-6. Epub 2020 Feb 19.

Department of Orbit & Oculoplasty, Vittala International Institute of Ophthalmology & Prabha Eye clinic and Research center, Bangalore, India.

: We report a series of orbital sarcoid in a south Indian patient population and their outcome.: Retrospective interventional case series.: Eleven out of 144cases of biopsy-proven sarcoidosis had orbital involvement. Read More

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http://dx.doi.org/10.1080/09273948.2019.1707235DOI Listing
February 2020

Bacteriological pattern and their correlation with complications in culture positive cases of acute bacterial conjunctivitis in a tertiary care hospital of upper Assam: A cross sectional study.

Medicine (Baltimore) 2020 Feb;99(7):e18570

Department of Pharmacology, PGIMER, Chandigarh.

Acute conjunctivitis is inflammation of conjunctiva of less than 3 to 4 weeks duration, characterized by cellular infiltration and exudation. It may also result into corneal, lid or orbital involvement which may lead to various complications.A hospital based prospective study was conducted in Assam Medical College and Hospital with 110 culture proven acute bacterial conjunctivitis cases. Read More

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http://dx.doi.org/10.1097/MD.0000000000018570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035090PMC
February 2020
5.723 Impact Factor

The Use of Stents in Children with Nasolacrimal Duct Obstruction Requiring Surgical Intervention: A Systematic Review.

Int J Environ Res Public Health 2020 02 7;17(3). Epub 2020 Feb 7.

Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.

Nasolacrimal duct obstruction (NLDO) is the most common cause of childhood epiphora. It is managed conservatively in the first year of life, after which surgical treatment is classically based on a stepwise paradigm of probing, intubation, and dacryocystorhinostomy. This systematic review aims to present the current role of intubation in the management of children with NLDO requiring surgical intervention. Read More

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http://dx.doi.org/10.3390/ijerph17031067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037191PMC
February 2020

[Diseases of the Lacrimal Gland].

Klin Monbl Augenheilkd 2020 May 3;237(5):703-723. Epub 2020 Feb 3.

Tear gland diseases are comparatively rare in daily ophthalmological practice. The aim of this article is on the one hand to present the necessary basic knowledge and on the other hand to draw a bow to important current publications on the subject in order to provide the reader with sufficient knowledge for daily practice after reading it.Inflammatory (acute and chronic specific dacryoadenitis, idiopathic dacryoadenitis), neoplastic (epithelial and nonepithelial) and structural (cysts etc. Read More

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http://dx.doi.org/10.1055/a-1068-7699DOI Listing

[The role of infection foci in the onset and sustenance of inflammatory diseases of the eye].

Vestn Oftalmol 2019 ;135(6):124-133

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Numerous clinical observations indicate the importance of the role of 'focal sepsis' in the development and facilitation of inflammation in the anterior eye segment. The article describes possible routes of infection spread from various local foci to the eye. Studying the connection between local infection foci and inflammatory eye diseases will give ophthalmologists more opportunities for effective treatment and prevention of disease recurrences. Read More

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http://dx.doi.org/10.17116/oftalma2019135061124DOI Listing
February 2020

Acute dacryocystitis with giant lacrimal abscess: a case report.

Ital J Pediatr 2020 Feb 3;46(1):15. Epub 2020 Feb 3.

Pediatrics Unit, Pisa University Hospital, Via Roma n. 67, 56126, Pisa, Italy.

Background: We report a case of a 4-year-old girl with acute dacryocystitis complicated with giant lacrimal abscess who underwent open dacryocystectomy as resolutive surgery.

Case Presentation: A 4-year-old previously healthy girl presented to the emergency department with a voluminous and erythematous, fluctuant warm mass localized inferiorly to the medial canthus of the right eye. She had a 2-week history of right inferior eyelid oedema and hyperemia, treated firstly with dexamethasone and netilmicin by eye drops, and then with per oral amoxicillin clavulanate. Read More

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http://dx.doi.org/10.1186/s13052-020-0779-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998065PMC
February 2020

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model.

Sci Rep 2020 01 29;10(1):1455. Epub 2020 Jan 29.

Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.

Autoimmune dacryoadenitis and altered lacrimal gland (LG) secretion are features of Sjögren's syndrome (SS). Activity of cathepsin S (CTSS), a cysteine protease, is significantly and specifically increased in SS patient tears. The soluble chemokine, CX3CL1 (fractalkine), is cleaved from membrane-bound CX3CL1 by proteases including CTSS. Read More

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http://dx.doi.org/10.1038/s41598-020-58337-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989636PMC
January 2020

HIF1α-mediated TRAIL Expression Regulates Lacrimal Gland Inflammation in Dry Eye Disease.

Invest Ophthalmol Vis Sci 2020 Jan;61(1)

,.

Purpose: The purpose of this study was to investigate the expression of death ligands in the lacrimal glands (LGs), identify upstream factors that regulate their expression, and determine the functional roles of these factors in the pathogenesis of dry eye disease (DED).

Methods: For DED experiment, ex vivo coculture system with LG and in vivo murine model using a controlled environment chamber were utilized. C57BL/6 mice and hypoxia-inducible factor (HIF)-1α conditional knockout (CKO) mice were used. Read More

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http://dx.doi.org/10.1167/iovs.61.1.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205192PMC
January 2020

Acute dacryocystitis in pediatric patients and frequency of nasolacrimal duct patency.

Orbit 2020 Jan 29:1-6. Epub 2020 Jan 29.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

: To study acute dacryocystitis in a pediatric age group, focusing on patients' demographic profiles, clinical presentation, and management outcome.: A retrospective case series of all acute dacryocystitis in pediatric patients (0-17 years) from two tertiary-care eye centres in Riyadh, Saudi Arabia was conducted. Demographic profile, risk factors, initial clinical presentation, management regimens, and final outcome were analysed. Read More

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http://dx.doi.org/10.1080/01676830.2020.1717548DOI Listing
January 2020

Pediatric acute dacryocystitis due to Eikenella corrodens: A case report.

J Infect Chemother 2020 May 23;26(5):510-512. Epub 2020 Jan 23.

Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

Eikenella corrodens is a facultatively anaerobic gram-negative rod bacterium in the oropharynx and respiratory tract. It is a member of HACEK (Haemophilus spp., Aggregatibacter spp. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.12.014DOI Listing

Orbital Lymphoma mimicking non-resolving dacryocystitis.

J Fr Ophtalmol 2020 Feb 14;43(2):175-176. Epub 2020 Jan 14.

Department of ophthalmology, hospital Clinico San Carlos, Calle del Prof Martín Lagos, s/n, 28040 Madrid, Spain.

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http://dx.doi.org/10.1016/j.jfo.2019.07.022DOI Listing
February 2020

Masquerading dacryocystitis.

Oxf Med Case Reports 2019 Dec 31;2019(12):504-506. Epub 2019 Dec 31.

Director of Oculofacial Plastic and Orbital Surgery, University of Kentucky, Lexington, KY 40506, USA.

Intravascular papillary endothelial hyperplasia (IPEH), otherwise known as Masson's tumor, is a benign lesion of the skin with no known malignant transformations reported. It is considered a non-neoplastic lesion, as it is reactive to some vascular insult, usually a thrombus in a vein leading to vascular endothelial cell proliferation. Masson's tumor typically presents as a slow-growing, indolent lesion commonly affecting the head, neck and arms with a female predominance. Read More

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http://dx.doi.org/10.1093/omcr/omz120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937449PMC
December 2019

Steroid Therapy and Steroid Response in Autoimmune Pancreatitis.

Int J Mol Sci 2019 Dec 30;21(1). Epub 2019 Dec 30.

Division of Endoscopy, Shizuoka Cancer Center 1007, Shimonagakubo, Nagaizumi, Suntogun, Shizuoka 411-8777, Japan.

Autoimmune pancreatitis (AIP), a unique subtype of pancreatitis, is often accompanied by systemic inflammatory disorders. AIP is classified into two distinct subtypes on the basis of the histological subtype: immunoglobulin G4 (IgG4)-related lymphoplasmacytic sclerosing pancreatitis (type 1) and idiopathic duct-centric pancreatitis (type 2). Type 1 AIP is often accompanied by systemic lesions, biliary strictures, hepatic inflammatory pseudotumors, interstitial pneumonia and nephritis, dacryoadenitis, and sialadenitis. Read More

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http://dx.doi.org/10.3390/ijms21010257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981453PMC
December 2019

Fibrous Dysplasia-like Lacrimal Sac Tumor Associated With Dacryocystitis.

Ophthalmic Plast Reconstr Surg 2020 Jan/Feb;36(1):e23-e24

From the Departments of Ophthalmology.

A 72-year-old woman who presented with right-sided epiphora and conjunctivitis underwent a probing and irrigation procedure with normal results. She improved with antibiotic-steroid drops. A swelling in the medial canthal region completely resolved. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001526DOI Listing
January 2020

Human umbilical cord mesenchymal stem cells alleviate ongoing autoimmune dacryoadenitis in rabbits via polarizing macrophages into an anti-inflammatory phenotype.

Exp Eye Res 2020 02 28;191:107905. Epub 2019 Dec 28.

Tianjin Key Laboratory of Retinal Functions and Diseases, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China. Electronic address:

Mesenchymal stem cells (MSCs) exhibit beneficial effects on autoimmune dacryoadenitis. However, the underlying mechanisms are not fully understood. In this study, we investigated the therapeutic effect of human umbilical cord mesenchymal stem cells (hUC-MSCs) on rabbit autoimmune dacryoadenitis, an animal model of Sjögren's syndrome (SS) dry eye, and explored whether the effects of MSCs were related to their modulation on macrophage polarization. Read More

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http://dx.doi.org/10.1016/j.exer.2019.107905DOI Listing
February 2020

An Unusual Presentation of Large B-cell Lymphoma.

Cureus 2019 Nov 18;11(11):e6180. Epub 2019 Nov 18.

Otolaryngology, Greenbrier Valley Medical Center, Fairlea, USA.

Primary Non-Hodgkin's lymphoma of the lacrimal sac is extremely rare. Symptoms are usually atypical and nonspecific, which often leads to the original misdiagnosis of dacryocystitis. The most common presenting features are epiphora, swelling, and acute dacryocystitis. Read More

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http://dx.doi.org/10.7759/cureus.6180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919955PMC
November 2019

Dacryoadenitis Associated With Juvenile Idiopathic Arthritis.

Ophthalmic Plast Reconstr Surg 2020 May/Jun;36(3):e63-e65

Department of Ophthalmology, University of California San Francisco, San Francisco, California, U.S.A.

A 14-year-old female with juvenile idiopathic arthritis presented with left-sided recurrent painful periorbital swelling of 5 months duration. MRI revealed enlargement of the left lacrimal gland with extensive inflammatory change involving the orbital and periorbital soft tissues. Lacrimal gland biopsy showed evidence of chronic inflammation, and she had intralesional steroid injection at the time of biopsy. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001573DOI Listing
December 2019

Loss of Pacer Spikes as electrocardiographic (EKG) Artifact Due to Microdebrider Use During Endoscopic Dacryocystorhinostomy.

Ophthalmic Plast Reconstr Surg 2020 Mar/Apr;36(2):e50-e51

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, U.S.A.

As intraoperative use of electronic equipment becomes more common, familiarity with the potential for electrocardiographic artifact generated by these instruments is increasingly important. The authors' patient underwent endoscopic dacryocystorhinostomy under general anesthesia for treatment of acute on chronic dacryocystitis secondary to acquired nasolacrimal duct obstruction. She had previously had pacemaker placement for treatment of sick sinus syndrome and low ejection fraction heart failure, and use of a microdebrider intraoperatively resulted in loss of pacer spikes and interference signal on electrocardiographic leading to placement of a magnet. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001562DOI Listing
December 2019

Predictive Value of Serum Angiotensin-Converting Enzyme Titers in Sarcoid-Like Dacryoadenitis.

Ophthalmic Plast Reconstr Surg 2020 Mar/Apr;36(2):144-147

Adnexal Service, Moorfields Eye Hospital, City Road, London, United Kingdom.

Purpose: To compare serum angiotensin-converting enzyme (sACE) titers in patients with newly diagnosed sarcoid-like dacryoadenitis and nongranulomatous dacryoadenitis.

Study Design: Retrospective comparative case series.

Patients And Methods: Clinical details and presenting sACE titers were reviewed for patients with newly diagnosed sarcoid-like dacryoadenitis (SLD) and nongranulomatous dacryoadenitis (NGD). Read More

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http://dx.doi.org/10.1097/IOP.0000000000001493DOI Listing
December 2019

Are systemic antibiotics required during and after dacryocystitis-related dacryocystorhinostomy?

Orbit 2019 Dec 20:1-2. Epub 2019 Dec 20.

Ophthalmic Plastic Surgery, Lions Eye Institute, Department of Ophthalmology, Albany Medical College, Albany, New York, USA.

: To compare the outcomes of patients with and without a history of dacryocystitis that undergo dacryocystorhinostomy without systemic intra- and post-operative antibiotics.: A retrospective review was performed to identify all cases of patients that received surgery under this paradigm and had at least three months of follow up care. Key demographic and outcome data were captured, and a statistical analysis was performed via a dedicated software package (Microsoft Excel, Redmond, WA). Read More

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http://dx.doi.org/10.1080/01676830.2019.1704798DOI Listing
December 2019

Two cases of epidemic keratoconjunctivitis-associated dacryocystitis.

Orbit 2019 Dec 18:1-4. Epub 2019 Dec 18.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

This report presents two cases of epidemic keratoconjunctivitis (EKC)-associated dacryocystitis. Both patients presented with preseptal edema. Orbital computed tomography (CT) scans were performed out of concern for orbital cellulitis and revealed soft tissue edema involving the preseptal aspect of the eyelids and also the lacrimal sac. Read More

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http://dx.doi.org/10.1080/01676830.2019.1705499DOI Listing
December 2019

Long-term Outcome of Incision and Curettage Treatment in Patients with Lacrimal Gland Ductulitis.

Korean J Ophthalmol 2019 Dec;33(6):487-492

Department of Ophthalmology, Saevit Eye Hospital, Goyang, Korea.

Purpose: To describe the effects and long-term outcomes of incision and curettage treatment in patients with lacrimal gland ductulitis.

Methods: Twenty-four patients (24 eyes) with lacrimal gland ductulitis who were treated at Saevit Eye Hospital from June 2010 to November 2016. All patients underwent incision and curettage through the lacrimal ductule, and granules or concretions were removed. Read More

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http://dx.doi.org/10.3341/kjo.2019.0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911786PMC
December 2019