2,237 results match your criteria Dacryoadenitis
Vestn Oftalmol 2018 ;134(5. Vyp. 2):270-275
Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, Chair of Ophthalmology, 8-2 Malaya Trubetskaya St., Moscow, Russian Federation, 119991.
The article reviews the literature devoted to modern intraoperative methods of preventing cicatricial process at the site of dacryostoma after endonasal endoscopic dacryocystorhinostomy. Despite the constant improvement of the surgery technique, complications in the postoperative period still occur. They include the formation of granulation tissue at the sites of dacryostoma, synechiae in the nasal cavity, or narrowing of the dacryostoma, which ultimately leads to a relapse of the disease. Read More
Vestn Oftalmol 2018 ;134(5. Vyp. 2):178-185
Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.
One of the most common and potentially threatening manifestations of granulomatosis with polyangiitis (GPA) is orbital lesion.
Purpose: To study the clinical course and prognosis of orbital lesions of various localization in GPA patients. Material and me-thods. Read More
Graefes Arch Clin Exp Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.
Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital, 1-1 Yazako-Karimata, Nagakute, Aichi, 480-1195, Japan.
Purpose: To examine the clinicopathological characteristics of patients with thyroid eye disease (TED) who showed asymmetric lacrimal gland enlargement.
Methods: Sixteen patients were included in this retrospective, observational case series. The following data were collected: sex, age, laterality, past medical history, laboratory results for thyroid function and other autoimmune disorders, pathological results, other systemic lesions related to lacrimal gland pathology, and the clinical course after treatment. Read More
Mymensingh Med J 2018 Oct;27(4):673-678
Dr Muhammad Rafiqul Islam, Junior Consultant, Department of Ophthalmology, Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh.
Nasolacrimal duct obstruction due to chronic dacryocystitis is the most common cause of epiphora. Dacryocystorhinostomy (DCR) is the treatment of choice for chronic dacryocystitis. This can be carried out by external, endoscopic and endolaser surgical approach. Read More
Am J Rhinol Allergy 2018 Nov 28:1945892418815044. Epub 2018 Nov 28.
4 Department of Otolaryngology-Head & Neck Surgery, Albaha University, Al Bahah, Saudi Arabia.
Background: Although several studies have commented on causes of dacryocystorhinostomy (DCR) failure, detailed description of anatomical findings in such cases remains insufficient.
Objective: Our objective was primarily to analyze radiologic, endoscopic, and intraoperative findings in patients presenting with failed DCR and secondarily to assess the outcome of revision endoscopic DCR (endo-DCR) carried out at our institution.
Methods: Twenty-four failed DCRs presenting to our tertiary care center were retrospectively analyzed. Read More
Indian J Otolaryngol Head Neck Surg 2018 Dec 19;70(4):477-481. Epub 2018 Sep 19.
Department of ENT, Gandhi Medical College, Bhopal, MP 462001 India.
Many surgical advancement paved to surgical success in endonasal endoscopic dacryocystorhinostomy. Mitomycin C is a systemic chemotherapeutic agent derived from that inhibits the synthesis of DNA, cellular RNA, and protein by inhibiting the synthesis of collagen by fibroblasts. The objective of the study was to evaluate the advantage of mitomycin C in primary endoscopic endonasal dacryocystorhinostomy without stenting. Read More
Vet Clin North Am Exot Anim Pract 2019 Jan;22(1):1-14
Comparative Ophthalmology, University of Georgia, 2200 College Station Road, Athens, GA 30202, USA. Electronic address:
Rabbits have become a popular house pet that is encountered with increasing frequency in small animal veterinary practice. The unique anatomy of the rabbit predisposes them to developing surface ocular problems including the development of dacryocystitis, as well as conjunctivitis and keratitis. This article endeavors to give an updated outline of the various conditions affecting the rabbit ocular surface, with emphasis on diagnosis and treatment. Read More
Otolaryngol Head Neck Surg 2018 Nov 20:194599818813123. Epub 2018 Nov 20.
1 Department of Otorhinolaryngology-Head and Neck Surgery, Army College of Medical Sciences and Associated Base Hospital, Delhi Cantt, New Delhi, India.
Objective: To compare the outcomes of various techniques of endoscopic dacryocystorhinostomy (DCR).
Study Design: Retrospective case record analysis.
Settings: Tertiary care referral center. Read More
J Craniofac Surg 2018 Nov 15. Epub 2018 Nov 15.
Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital.
Sarcoidosis rarely develops in the lacrimal sac. Lacrimal sac sarcoidosis may be associated with sarcoidosis-related rhinosinusitis. The anatomical and histological relationship between the lacrimal drainage system and nasal mucosa has been indicated as a predisposing factor for this concomitance. Read More
Orbit 2018 Nov 13:1-5. Epub 2018 Nov 13.
a Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute , Hyderabad , India.
Purpose: The aim of this study was to perform a histopathological assessment of the efficacy of sclerosing agents in dacryocystosclerotherapy (DCST) and to evaluate its role as an alternative to dacryocystectomy (DCT) in a specific group of patients.
Methods: Thirteen lacrimal drainage systems of 10 patients with primary acquired nasolacrimal duct obstruction (PANDO) were studied. All patients were awaiting a DCT, indications being repeated attacks of dacryocystitis with severe systemic or ocular co-morbidities and/or refusal for a dacryocystorhinostomy. Read More
BMC Ophthalmol 2018 Oct 30;18(1):283. Epub 2018 Oct 30.
Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, 1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Background: Universal ocular screening of infants is not a standard procedure in children's health care system in China. This pilot study investigated prevalence of ocular abnormalities of 6 weeks-age infants using wide-field digital imaging system.
Methods: Infants aged 6 weeks around were consecutively enrolled in a public hospital between April 2015 and August 2016. Read More
Int J Pediatr Otorhinolaryngol 2018 Dec 19;115:54-57. Epub 2018 Sep 19.
Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital, Aichi, Japan.
Objective: To examine the surgical outcome of dacryoendoscopy-assisted nasal endoscopic marsupialization for congenital dacryocystocele.
Methods: This is a retrospective, observational study that included 7 sides of 6 patients with congenital dacryocystocele. The surgical indication in 5 of the patients was acute dacryocystitis while one of the patients had no spontaneous resolution after long-term observation. Read More
J Control Release 2018 Oct 23;292:183-195. Epub 2018 Oct 23.
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, United States; Department of Ophthalmology, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States. Electronic address:
As a potent macrolide immunosuppressant, cyclosporine A (CsA) is used to treat multiple autoimmune diseases, including non-autoimmune and autoimmune-mediated dry eye disease, rheumatoid arthritis and psoriasis. Despite its potency, CsA has poor solubility, poor bioavailability, and can cause serious adverse reactions such as nephrotoxicity and neurotoxicity. To overcome these limitations, we invented a new strategy to carry CsA by fusing its cognate human receptor, cyclophilin A (CypA), to a 73 kDa elastin-like polypeptide (ELP) termed A192 using recombinant protein expression. Read More
Mod Rheumatol 2018 Oct 25:1-5. Epub 2018 Oct 25.
a Department of Rheumatology and Clinical Immunology , School of Medicine, Sapporo Medical University , Hokkaido , Japan.
Objectives: Immunoglobulin (Ig) G4-related disease (IgG4-RD) is often complicated by allergic disorders. This study was conducted to investigate the mechanism of type 2 helper T-inflammation (Th2-inflammation) in IgG4-related dacryoadenitis and sialadenitis (IgG4-DS).
Methods: We separated and analyzed the proportion of growth stimulation expressed gene 2 (ST2) memory Th2 cells among the peripheral blood mononuclear cells by flow cytometry in cases with IgG4-DS and healthy individuals. Read More
Int J Mol Sci 2018 Oct 20;19(10). Epub 2018 Oct 20.
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Nonobese diabetic (NOD) mice spontaneously develop lacrimal and salivary gland autoimmunity similar to human Sjögren syndrome. In both humans and NOD mice, the early immune response that drives T-cell infiltration into lacrimal and salivary glands is poorly understood. In NOD mice, lacrimal gland autoimmunity spontaneously occurs only in males with testosterone playing a role in promoting lacrimal gland inflammation, while female lacrimal glands are protected by regulatory T cells (Tregs). Read More
Clin Ophthalmol 2018 25;12:1859-1864. Epub 2018 Sep 25.
School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Background: The prevalence of bacterial pathogens isolated from patients with acute and chronic dacryocystitis and the pattern of antibiotic susceptibility tests are varied in each region. Moreover, the management of dacryocystitis is only based on clinical observations without microbiological evaluation. The present study aimed to identify epidemiologic and etiologic factors of dacryocystitis in our geographical area. Read More
Wideochir Inne Tech Maloinwazyjne 2018 Sep 10;13(3):401-406. Epub 2018 Jul 10.
Department of Ophthalmology, University of Health Sciences, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Introduction: Transcanalicular laser DCR (TL-DCR) approaches have been developed for the formation of a fistula between the nasal cavity and the lacrimal sac to ensure the continuity of the lacrimal drainage system over the years. However, the success rate of TL-DCR has varied widely.
Aim: To evaluate and compare the success rates of conventional transcanalicular multidiode laser dacryocystorhinostomy and modified transcanalicular multidiode laser dacryocystorhinostomy. Read More
Eur J Ophthalmol 2018 Oct 1:1120672118803510. Epub 2018 Oct 1.
Department of Oculoplastic, Orbital & Lacrimal Surgery, Aichi Medical University Hospital, Nagakute, Japan.
Purpose: To present cases of primary lacrimal sac lymphoma in a Japanese population.
Methods: In this retrospective case series, five cases (two males and three females; mean age: 49.8 years; age range: 38-62 years) were included. Read More
Saudi J Ophthalmol 2018 Jul-Sep;32(3):253-256. Epub 2017 Dec 24.
HIMSR, New Delhi, India.
We report a case of young adult female with swelling in the superolateral aspect of left orbit for two weeks which was diagnosed as tubercular dacryoadenitis with intracranial extension without any neurological features. Tubercular dacryoadenitis is very rare but still makes an important differential diagnosis of lacrimal gland swellings especially in endemic areas like India. Few cases of tubercular dacryoadenitis have been reported in the past; but not a single case with intracranial extension in young adults with short history and without neurological symptoms. Read More
Exp Eye Res 2018 Nov 8;176:243-251. Epub 2018 Sep 8.
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, United States; Department of Ophthalmology, Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address:
The male Non-Obese Diabetic (NOD) mouse is an established model of autoimmune dacryoadenitis characteristic of Sjögren's Syndrome (SS), but development of diabetes may complicate studies. The Non-Obese Diabetes Resistant (NOR) mouse is a MHC-II matched diabetes-resistant alternative, but development of autoimmune dacryoadenitis is not well-characterized. We compare features of SS in male NOD and NOR mice at 12 and 20 weeks. Read More
PLoS One 2018 7;13(9):e0203705. Epub 2018 Sep 7.
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Objective: To retrospectively identify epidemiological trends of infection on the ocular surface and investigate trends of resistance to bacterial antibiotics compared with 10-years previous for Staphylococcus aureus, coagulase-negative staphylococci (CNS), and Corynebacterium in Japan.
Materials And Methods: Bacterial isolate samples were collected from the conjunctival sacs of eyes afflicted with conjunctivitis, keratitis, dacryocystitis, and hordeolum from September 2004 through November 2005 (n = 145 isolates) and September 2014 through November 2015 (n = 195 isolates) at the Baptist Eye Institute, Kyoto, Japan. The prevalence of methicillin-resistant S. Read More
Graefes Arch Clin Exp Ophthalmol 2018 Nov 5;256(11):2103-2112. Epub 2018 Sep 5.
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan, 430030, China.
Purpose: The aim of this study was to explore the pathological changes of the nasolacrimal duct in rabbits with experimentally induced obstructive dacryocystitis in correlation with lacrimal endoscopic findings.
Methods: The rabbit model of obstructive dacryocystitis was created by injecting 0.15 ml of self-curing resin into the lacrimal duct. Read More
J Rheumatol 2018 Aug;45(9):1339-1340
Department of Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan. This work was supported by the Research on Measures for Intractable Diseases Project matching fund subsidy from the Ministry of Health, Labor, and Welfare, Japan, and the Japan Agency for Medical Research and Development.
Orbit 2018 Aug 24:1-4. Epub 2018 Aug 24.
c Department of Pathology , Maulana Azad Medical College & Associated Lok Nayak Hospital , Delhi , India.
Tuberculosis is an airborne communicable disease primarily affecting lungs. Primary tuberculosis of the lacrimal sac is very rare. A 15-year-old girl presented with bilateral epiphora for 8 months. Read More
Ophthalmic Plast Reconstr Surg 2018 Aug 21. Epub 2018 Aug 21.
Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Bronx, New York, U.S.A.
Purpose: To review and summarize the clinical features, presentations, diagnostic modalities, and management of ophthalmic manifestations of eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss Syndrome).
Methods: A systematic PubMed search of all English articles on EGPA with ophthalmic involvement was performed. Emphasis was placed on English-language articles, but any article with an abstract translated into English was also included. Read More
Biomarkers 2018 Sep 12:1-12. Epub 2018 Sep 12.
a Department of Ophthalmology, USC Keck School of Medicine , Roski Eye Institute , Los Angeles , CA , USA.
Context: Cathepsin S (CTSS) activity is elevated in Sjögren's Syndrome (SS) patient tears.
Objective: To evaluate longitudinal expression of tear and tissue CTSS activity relative to other disease indicators in Non-Obese Diabetic (NOD) mice.
Methods: CTSS activity was measured in tears and lacrimal glands (LG) from male 1-6 month (M) NOD and 1 and 6 M BALB/c mice. Read More
Middle East Afr J Ophthalmol 2018 Apr-Jun;25(2):71-80
Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.
Idiopathic orbital inflammation (IOI) is a benign inflammatory condition usually confined to the orbit but extraorbital extension can also occur. IOI has been classified into categories including anterior, diffuse, posterior or apical, myositis, and dacryoadenitis. Other rare types of IOI include periscleritis, perineuritis, and focal mass. Read More
Can J Ophthalmol 2018 Aug 11;53(4):e132-e134. Epub 2017 Dec 11.
Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. Electronic address:
BMC Res Notes 2018 Aug 17;11(1):597. Epub 2018 Aug 17.
Department of Ophthalmology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Objectives: Empirical selections of antimicrobial therapy based on clinical observations are common clinical practices in Ethiopia. This study identified common external ocular infections and determined antibiotic susceptibility testing in northwest Ethiopia.
Results: Among 210 patients studied, conjunctivitis 32. Read More
Int J Surg Case Rep 2018 9;50:130-134. Epub 2018 Aug 9.
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Introduction: Acute dacryocystitis usually presents as a pre-septal cellulitis since the lacrimal sac lies anterior to the orbital septum. Orbital cellulitis secondary to acute dacryocystitis is very rare due to a variety of anatomic barriers to the orbit but can occur and result in abscess formation with risk of visual compromise.
Presentation Of Case: We describe a case of otherwise healthy adult who presented with complete visual loss following orbital cellulitis and abscess formation secondary to acute dacryocystitis. Read More
JAMA Ophthalmol 2018 Oct;136(10):1207-1208
Department of Ophthalmology, University of California, San Francisco.
N Engl J Med 2018 Aug;379(5):474
Boston Children's Hospital, Boston, MA
Can J Cardiol 2018 Aug 2;34(8):1088.e7-1088.e10. Epub 2018 May 2.
Department of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.
We report the case of a 65-year-old man referred to our department because of a complex coronary aneurysmal disease presenting as subacute ST-segment elevation myocardial infarction due to intraluminal thromboembolism. The patient's past medical history (recurrent episodes of lymphadenopathies, parotid swelling, prostatitis, and dacryoadenitis) raised the suspicion of a unifying systemic disorder with coronary involvement. An extensive infectious and autoimmune screening was performed, leading to the final diagnosis of IgG4-related disease. Read More
Rev Med Interne 2018 Jul 24. Epub 2018 Jul 24.
Service de médecine interne, hôpital Purpan, place du Docteur-Baylac, TSA 40031, 31059 Toulouse cedex 9, France.
Ned Tijdschr Geneeskd 2018 Jul 13;162. Epub 2018 Jul 13.
Franciscus Gasthuis en Vlietland, afd. Kindergeneeskunde, Rotterdam.
Newborn twins both had a blue, smooth tumour in the inner angle of the orbit; one of them had two such tumours. They were diagnosed with congenital dacryocystoceles. If decompression into the nose is not effective, patients should undergo probing early in life to reduce the incidence of dacryocystitis and orbital cellulitis. Read More
Curr Opin Ophthalmol 2018 Sep;29(5):458-468
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Purpose Of Review: The goal of this article is to review the key clinical and radiological features, treatment strategies, and prognosis of lacrimal gland tumors.
Recent Findings: Debulking of the orbital lobe of the lacrimal gland may offer improved control rates in dacryoadenitis without compromise of tear film function. Contrary to previous belief, careful biopsy of the lacrimal gland prior to excision does not appear to increase the risk of recurrence in cases with suspected pleomorphic adenoma. Read More
HNO 2018 Oct;66(10):751-759
Universitätsklinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsklinikum Halle (Saale), Halle, Deutschland.
Background: The cardinal symptom of lacrimal stenosis is epiphora and a subjective high level of discomfort due to continuous dacryorrhea.
Objective: The aim of the current paper is to present a structured review of common diagnostic and therapeutic strategies for lacrimal stenosis.
Materials And Methods: The most important diagnostic and therapeutic approaches are analysed using the existing literature and by reporting the authors' own experiences. Read More
J Laryngol Otol 2018 Aug 12;132(8):718-723. Epub 2018 Jul 12.
Department of Otolaryngology, Head and Neck Surgery,Okmeydanı Research and Training Hospital,Istanbul,Turkey.
Objective: This prospective, controlled study assessed how placing a stent into a newly formed ostium affects ostial patency, success and complication rates in endoscopic dacryocystorhinostomy patients.
Methods: In group 1 (40 eyes of 36 patients), both silicone tube intubation and tube stenting were performed. In group 2 (36 eyes of 34 patients), only silicone tube intubation was performed. Read More
Arq Bras Oftalmol 2018 Jul-Aug;81(4):341-343
Central Lisbon Hospital Center, Lisbon - Portugal.
Chronic lacrimal canaliculitis is a rare infection of the lacrimal system, and can lead to misdiagnosis due to its overlapping presentation to other common entities. The authors report a case of lacrimal canaliculitis with a three-year history of recurrent unilateral red eye and mucopurulent discharge. Here, we describe the clinical course, surgical details, and microbial analysis of canaliculitis infection. Read More
Am J Ophthalmol Case Rep 2018 Sep 22;11:41-44. Epub 2018 May 22.
Department of Ophthalmology, Osaka Medical College, Takatsuki City, Osaka, Japan.
Purpose: To report a case of prolonged placement of a lacrimal silicone tube for 20 years, with evaluation of the lacrimal duct using lacrimal micro-endoscopy and inspection of deformation of the lacrimal tube.
Observations: This study involved a case of dacryocystitis in which a silicone tube had been placed in the patient 20-years previous and that was treated conservatively. Although granulation tissue formation due to dacryocystitis in the lacrimal duct was observed under lacrimal micro-endoscopy, subjective and objective resolution of symptoms, including granulated tissue formation, was achieved after removal of the silicone tube and conservative medical treatment. Read More
Indian J Otolaryngol Head Neck Surg 2018 Jun 17;70(2):299-305. Epub 2018 Feb 17.
Department of ENT, Gandhi Medical College, Bhopal, MP 462001 India.
To study the outcome and complications of endoscopic endonasal dacryocystrhinostomy without stenting. Randomised prospective observational design. Tertiary academic centre. Read More
Indian J Otolaryngol Head Neck Surg 2018 Jun 7;70(2):295-298. Epub 2018 Feb 7.
Nehru Nagar, Bhopal, Madhya Pradesh India.
Dacryocystitis is defined as inflammation of lacrimal sac. This can be congenital or acquired. Congenital dacryocystitis is commonly chronic while acquired dacryocystitis is acute and chronic both. Read More
Ocul Immunol Inflamm 2018 Jun 29:1-7. Epub 2018 Jun 29.
a Department of Ophthalmology, Advanced Eye Centre , Post Graduate Institute of Medical Education and Research , Chandigarh , India.
Purpose: To describe the clinico-radiological features and long-term outcomes in patients with tubercular dacryoadenitis (TbD) Methods: Retrospective, observational study of TbD patients who underwent a thorough clinical examination, orbital imaging study, and tailored ancillary investigations. Polymerase chain reaction (PCR) and microscopy were done in specific cases. A 4-drug anti-tubercular therapy (ATT) was started and clinical response was monitored in all. Read More
Vestn Otorinolaringol 2018;83(3):88-93
Federal budgetary institution of science 'G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology Clinical Otorhinolaryngology, Federal Service on Surveillance for Consumer Rights Protection and Human Well-Being', Moscow, Russia, 125212.
The primary objective of the present study was to highlight the current state of research on the pathology of the lacrimal organs based on the results of the analysis of the relevant publications in the domestic and foreign scientific literature. Special attention in this review is given to the problems of diagnostics, indications for the probing, the treatment and stenting strategies. The authors report their original observations contributing to the better understanding of the anatomical features of the nasolacrimal passages. Read More
Medicine (Baltimore) 2018 Jun;97(26):e11318
Department of Ophthalmology, The Affiliated Hospital of Guizhou Medical University, Guiyang.
The aim of the study was to review the distribution, current trends, and microbiological characteristics of bacterial pathogens isolated from dacryocystitis patients in China during the last 15 years.This is a retrospective multiple-center noncomparative case series. The medical records of 15,452 consecutive patients from 7 cities diagnosed as having dacryocystitis between 2002 and 2016 were reviewed. Read More
Ophthalmic Plast Reconstr Surg 2018 Jun 21. Epub 2018 Jun 21.
Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria.
Purpose: To describe the demographics, presentation, treatment, and outcome in 10 cases of lacrimal sac diverticulum and to review the literature on this topic, and to determine the incidence of diverticula from a series of dacryocystograms.
Methods: Data were collected for all consecutive patients with lacrimal sac diverticulum seen between 2003 and 2015, including patient demographics, clinical presentation, imaging findings, treatment, and follow-up. A systematic literature review was performed for cases of lacrimal sac diverticulum. Read More
J Autoimmun 2018 Sep 20;93:45-56. Epub 2018 Jun 20.
Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA. Electronic address:
CD25 knock-out (CD25KO) mice spontaneously develop Sjögren Syndrome (SS)-like inflammation. We investigated the role of commensal bacteria by comparing CD25KO mice housed in conventional or germ-free conditions. Germ-free CD25KO mice have greater corneal barrier dysfunction, lower goblet cell density, increased total lymphocytic infiltration score, increased expression of IFN-γ, IL-12 and higher a frequency of CD4IFN-γ cells than conventional mice. Read More
Ophthalmic Plast Reconstr Surg 2018 Jun 19. Epub 2018 Jun 19.
Stein Eye Institute, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, U.S.A.
Purpose: To compare the results of cultures of the proximal and distal segments of silicone tubes after dacryocystorhinostomy.
Methods: The medical records of patients undergoing a dacryocystorhinostomy and silicone intubation were reviewed. The inclusion criteria were cultures of both distal and proximal stent segments after removal, dye testing, evaluation of the tear meniscus, and notation of the presence or absence of discharge before and after removal. Read More
APMIS 2018 Jun;126(6):459-476
The James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Boston, MA, USA.
Immunoglobulin G4-related disease (IgG4-RD) is an uncommon disorder that demonstrates characteristic clinicopathologic features including sclerosing lesions with storiform fibrosis, increased IgG4+ plasma cells with an increased IgG4+/IgG+ plasma cell ratio, obliterative phlebitis, and often an increased serum IgG4 level. This review summarizes the characteristic histopathologic and clinical features of IgG4-RD with detailed discussion of the histopathologic characteristics of the most commonly involved anatomic sites. We also present recent advances in our understanding of the pathophysiologic mechanisms of IgG4-RD and discuss updates on the treatment, prognosis, and outcomes of this rare disease, including discussion of the possible association between IgG4-RD and malignancy. Read More
Medicine (Baltimore) 2018 Jun;97(25):e11182
Department of Pathology, Second Hospital of Jilin University, Jilin University, Changchun, Jilin, P.R. China.
Rationale: Sporotrichosis is the most common subcutaneous mycosis. It is caused by the dimorphic fungus Sporothrix schenckii. Ocular sporotrichosis is uncommon and has been rarely reported. Read More